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Gene: NPNT (nephronectin) Homo sapiens
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Symbol: NPNT
Name: nephronectin
Description: Predicted to have integrin binding activity. Predicted to be involved in several processes, including cell-cell adhesion mediated by integrin; positive regulation of ERK1 and ERK2 cascade; and positive regulation of osteoblast differentiation. Localizes to collagen-containing extracellular matrix and extracellular exosome. Predicted to colocalize with integrin alpha8-beta1 complex; INTERACTS WITH 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine; aflatoxin B1.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: EGFL6L; POEM; preosteoblast EGF-like repeat protein with MAM domain; protein EGFL6-like
Orthologs:
Mus musculus (house mouse) : Npnt (nephronectin)  MGI  Alliance
Rattus norvegicus (Norway rat) : Npnt (nephronectin)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Npnt (nephronectin)
Pan paniscus (bonobo/pygmy chimpanzee) : NPNT (nephronectin)
Canis lupus familiaris (dog) : NPNT (nephronectin)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Npnt (nephronectin)
Sus scrofa (pig) : NPNT (nephronectin)
Chlorocebus sabaeus (African green monkey) : NPNT (nephronectin)
Heterocephalus glaber (naked mole-rat) : Npnt (nephronectin)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl4105,894,775 - 106,004,027 (+)EnsemblGRCh38hg38GRCh38
GRCh384105,895,453 - 105,971,671 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh374106,816,588 - 106,892,828 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 364107,036,054 - 107,112,277 (+)NCBINCBI36hg18NCBI36
Celera4104,115,729 - 104,192,091 (+)NCBI
Cytogenetic Map4q24NCBI
HuRef4102,551,277 - 102,627,657 (+)NCBIHuRef
CHM1_14106,793,392 - 106,869,624 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on NPNT
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1604498
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.