GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | MYC | affects expression | EXP | | 6480464 | CTD | Phenobarbital affects the expression of MYC mRNA | PMID:19159669 | MYC | increases expression | EXP | | 6480464 | CTD | Phenobarbital results in increased expression of MYC mRNA | PMID:19084549 | MYC | decreases methylation | ISO | Myc (Rattus norvegicus) | 6480464 | CTD | Phenobarbital results in decreased methylation of MYC promoter | PMID:30141584 | MYC | increases expression | ISO | Myc (Mus musculus) | 6480464 | CTD | Phenobarbital results in increased expression of MYC mRNA | PMID:19482888 | MYC | increases expression | ISO | Myc (Rattus norvegicus) | 6480464 | CTD | Phenobarbital results in increased expression of MYC mRNA | PMID:19162173 PMID:30141584 | MYC | increases response to substance | ISO | Myc (Mus musculus) | 6480464 | CTD | MYC gene results in increased susceptibility to Phenobarbital | PMID:8807143 | MYC | multiple interactions | ISO | Myc (Mus musculus) | 6480464 | CTD | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of MYC mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of MYC protein; [MYC gene co-treated with HGF gene] results in decreased susceptibility to Phenobarbital; [Phenobarbital co-treated with MYC protein] results in increased expression of BAX protein; NR1I3 protein affects the reaction [Phenobarbital results in increased expression of MYC mRNA]; NR1I3 protein promotes the reaction [Phenobarbital results in increased expression of MYC mRNA]; Phenobarbital inhibits the reaction [MYC protein results in decreased expression of BCL2 protein]; Phenobarbital inhibits the reaction [MYC protein results in increased expression of BAX protein]; Phenobarbital inhibits the reaction [MYC protein results in increased expression of TRP53 protein] | PMID:10425313 PMID:10449034 PMID:19482888 PMID:24535843 PMID:8807143 PMID:9230198 | MYC | multiple interactions | ISO | Myc (Rattus norvegicus) | 6480464 | CTD | [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of MYC mRNA; [Diethylnitrosamine co-treated with Phenobarbital] results in increased expression of MYC protein | PMID:20935162 PMID:7576107 | |
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