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Gene: CHGA (chromogranin A) Homo sapiens
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Symbol: CHGA
Name: chromogranin A
Description: Involved in several processes, including defense response to bacterium; mast cell chemotaxis; and mast cell cytokine production. Localizes to the perinuclear region of cytoplasm. Implicated in IgA glomerulonephritis; end stage renal failure; hypertension; and prostate cancer. Biomarker of end stage renal failure and pheochromocytoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: betagranin (N-terminal fragment of chromogranin A); catestatin; CGA; chromofungin; chromogranin-A; parathyroid secretory protein 1; pituitary secretory protein I; SP-I
Orthologs:
Mus musculus (house mouse) : Chga (chromogranin A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Chga (chromogranin A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chga (chromogranin A)
Pan paniscus (bonobo/pygmy chimpanzee) : CHGA (chromogranin A)
Canis lupus familiaris (dog) : CHGA (uncharacterized CHGA)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chga (chromogranin A)
Sus scrofa (pig) : CHGA (chromogranin A)
Chlorocebus sabaeus (green monkey) : CHGA (chromogranin A)
Heterocephalus glaber (naked mole-rat) : Chga (chromogranin A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1492,923,150 - 92,935,285 (+)Ensembl
GRCh381492,922,594 - 92,935,293 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371493,389,445 - 93,401,638 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361492,459,198 - 92,471,391 (+)NCBINCBI36hg18NCBI36
Build 341492,459,244 - 92,471,389NCBI
Celera1473,443,584 - 73,455,777 (+)NCBI
Cytogenetic Map14q32.12NCBI
HuRef1473,571,127 - 73,583,341 (+)NCBIHuRef
CHM1_11493,327,694 - 93,339,887 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CHGA
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730836
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.