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Gene: CHI3L1 (chitinase 3 like 1) Homo sapiens
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Symbol: CHI3L1
Name: chitinase 3 like 1
Description: Exhibits chitin binding activity. Involved in several processes, including positive regulation of intracellular signal transduction; response to interleukin-1; and response to interleukin-6. Localizes to the extracellular space. Implicated in asthma and schizophrenia. Biomarker of several diseases, including artery disease (multiple); diabetes mellitus (multiple); hematologic cancer (multiple); lung disease (multiple); and reproductive organ cancer (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 39 kDa synovial protein; ASRT7; cartilage glycoprotein 39; CGP-39; chitinase 3-like 1 (cartilage glycoprotein-39); chitinase-3-like protein 1; DKFZp686N19119; FLJ38139; GP-39; GP39; HC-gp39; hCGP-39; HCGP-3P; YK-40; YKL-40; YKL40; YYL-40
Orthologs:
Mus musculus (house mouse) : Chil1 (chitinase-like 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Chi3l1 (chitinase 3 like 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Chi3l1 (chitinase 3 like 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CHI3L1 (chitinase 3 like 1)
Canis lupus familiaris (dog) : CHI3L1 (chitinase 3 like 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Chi3l1 (chitinase 3 like 1)
Sus scrofa (pig) : CHI3L1 (chitinase 3 like 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381203,178,931 - 203,186,704 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371203,148,059 - 203,155,978 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361201,414,682 - 201,422,545 (-)NCBINCBI36hg18NCBI36
Build 341199,879,586 - 199,887,534NCBI
Celera1176,277,300 - 176,285,163 (-)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1174,313,188 - 174,321,051 (-)NCBIHuRef
CHM1_11204,570,380 - 204,578,243 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on CHI3L1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732419
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.