KCNQ1 (potassium voltage-gated channel subfamily Q member 1)

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Gene: KCNQ1 (potassium voltage-gated channel subfamily Q member 1) Homo sapiens

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Symbol:

KCNQ1

Name:

potassium voltage-gated channel subfamily Q member 1

RGD ID:

1353354

HGNC Page

HGNC

Description:

Enables several functions, including calmodulin binding activity; protein kinase A binding activity; and voltage-gated potassium channel activity. Contributes to delayed rectifier potassium channel activity. Involved in several processes, including ion transmembrane transport; regulation of heart contraction; and regulation of ion transmembrane transport. Located in several cellular components, including basolateral plasma membrane; endosome; and membrane raft. Part of voltage-gated potassium channel complex. Implicated in heart conduction disease (multiple) and long QT syndrome (multiple). Biomarker of seminoma.

Type:

protein-coding

RefSeq Status:

REVIEWED

Also known as:

ATFB1; ATFB3; FLJ26167; IKs producing slow voltage-gated potassium channel subunit alpha KvLQT1; JLNS1; KCNA8; KCNA9; kidney and cardiac voltage dependend K+ channel; KQT-like 1; Kv1.9; Kv7.1; KVLQT1; LQT; LQT1; potassium channel, voltage gated KQT-like subfamily Q, member 1; potassium voltage-gated channel subfamily KQT member 1; potassium voltage-gated channel, KQT-like subfamily, member 1; RWS; slow delayed rectifier channel subunit; SQT2; voltage-gated potassium channel subunit Kv7.1; WRS

RGD Orthologs

Mouse

Rat

Chinchilla

Bonobo

Dog

Squirrel

Pig

Green Monkey

Naked Mole-Rat

Alliance Genes

More Info

more info ...

Allele / Splice:

See ClinVar data

Latest Assembly:

GRCh38 - Human Genome Assembly GRCh38

Position:

Human Assembly	Chr	Position (strand)	Source	Genome Browsers
Human Assembly	Chr	Position (strand)	Source	JBrowse	NCBI	UCSC	Ensembl
GRCh38.p13 Ensembl	11	2,444,684 - 2,849,105 (+)	Ensembl	GRCh38		hg38	GRCh38
GRCh38	11	2,445,008 - 2,849,110 (+)	NCBI	GRCh38	GRCh38	hg38	GRCh38
GRCh37	11	2,466,238 - 2,870,340 (+)	NCBI	GRCh37	GRCh37	hg19	GRCh37
Build 36	11	2,422,797 - 2,826,916 (+)	NCBI	NCBI36		hg18	NCBI36
Build 34	11	2,439,259 - 2,826,915	NCBI
Celera	11	2,501,049 - 2,905,069 (+)	NCBI
Cytogenetic Map	11	p15.5-p15.4	NCBI
HuRef	11	2,256,184 - 2,658,673 (+)	NCBI		HuRef
CHM1_1	11	2,465,155 - 2,869,215 (+)	NCBI		CHM1_1

JBrowse:

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Model

Annotation Click to see Annotation Detail View

Gene Annotator (Functional Annotation) unavailable	Gene Annotator (Annotation Distribution) unavailable	Variant Visualizer (Genomic Variants) unavailble Variant Visualizer (Genomic Variants) unavailable
Gene Annotator (Functional Annotation)	Gene Annotator (Annotation Distribution)	Variant Visualizer (Genomic Variants)

InterViewer (Protein-Protein Interactions) unavailable	Gviewer (Genome Viewer) unavailable	Variant Visualizer (Damaging Variants) unavailble Variant Visualizer (Damaging Variants) unavailable
InterViewer (Protein-Protein Interactions)	GViewer (Genome Viewer)	Variant Visualizer (Damaging Variants)

Gene Annotator (Annotation Comparison) unavailable	OLGA (Gene List Generator) unavailable
Gene Annotator (Annotation Comparison)	OLGA (Gene List Generator)	Excel (Download)

MOET (Multi-Ontology Enrichement) unavailable	GOLF (Gene-Ortholog Location Finder) unavailable
MOET (Multi-Ontology Enrichement)	GOLF (Gene-Ortholog Location Finder)

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Imported Disease Annotations - ClinVar