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Gene: BCHE (butyrylcholinesterase) Homo sapiens
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Symbol: BCHE
Name: butyrylcholinesterase
RGD ID: 732174
Description: Exhibits cholinesterase activity and identical protein binding activity. Predicted to be involved in cocaine metabolic process. Localizes to blood microparticle. Implicated in Alzheimer's disease; coronary artery disease (multiple); diabetes mellitus (multiple); epilepsy; and inherited metabolic disorder. Biomarker of several diseases, including bacterial meningitis; dementia; familial hyperlipidemia; hypertension; and neurodegenerative disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: acylcholine acylhydrolase; BCHED; butyrylcholine esterase; CHE1; CHE2; choline esterase II; cholinesterase; cholinesterase (serum) 2; cholinesterase 1; E1; pseudocholinesterase
Orthologs:
Mus musculus (house mouse) : Bche (butyrylcholinesterase)  MGI  Alliance
Rattus norvegicus (Norway rat) : Bche (butyrylcholinesterase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Bche (butyrylcholinesterase)
Pan paniscus (bonobo/pygmy chimpanzee) : BCHE (butyrylcholinesterase)
Canis lupus familiaris (dog) : BCHE (butyrylcholinesterase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Bche (butyrylcholinesterase)
Sus scrofa (pig) : BCHE (butyrylcholinesterase)
Chlorocebus sabaeus (African green monkey) : BCHE (butyrylcholinesterase)
Heterocephalus glaber (naked mole-rat) : Bche (butyrylcholinesterase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl3165,772,904 - 165,837,462 (-)EnsemblGRCh38hg38GRCh38
GRCh383165,772,904 - 165,837,423 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373165,490,692 - 165,555,260 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363166,973,386 - 167,037,947 (-)NCBINCBI36hg18NCBI36
Build 343166,973,394 - 167,037,952NCBI
Celera3163,889,280 - 163,954,027 (-)NCBI
Cytogenetic Map3q26.1NCBI
HuRef3162,859,251 - 162,924,002 (-)NCBIHuRef
CHM1_13165,453,437 - 165,518,145 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on BCHE
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732174
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.