OSGIN1 (oxidative stress induced growth inhibitor 1) - Rat Genome Database

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Gene: OSGIN1 (oxidative stress induced growth inhibitor 1) Homo sapiens
Analyze
Symbol: OSGIN1
Name: oxidative stress induced growth inhibitor 1
RGD ID: 1607033
HGNC Page HGNC:30093
Description: Enables growth factor activity. Involved in negative regulation of cell growth.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: BDGI; BMSC-derived growth inhibitor; bone marrow stromal cell-derived growth inhibitor; huOKL38; OKL38; ovary, kidney and liver protein 38; oxidative stress-induced growth inhibitor 1; pregnancy induced growth inhibitor; pregnancy-induced growth inhibitor OKL38
RGD Orthologs
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Orthologs
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381683,953,240 - 83,966,332 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1683,931,311 - 83,966,332 (+)EnsemblGRCh38hg38GRCh38
GRCh371683,986,845 - 83,999,937 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361682,540,173 - 82,557,438 (+)NCBINCBI36Build 36hg18NCBI36
Celera1668,283,632 - 68,302,337 (+)NCBICelera
Cytogenetic Map16q23.3NCBI
HuRef1669,737,904 - 69,751,578 (+)NCBIHuRef
CHM1_11685,398,355 - 85,411,465 (+)NCBICHM1_1
T2T-CHM13v2.01690,019,300 - 90,032,388 (+)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(1->4)-beta-D-glucan  (ISO)
1,2-dichloroethane  (ISO)
1,2-dimethylhydrazine  (ISO)
1-naphthyl isothiocyanate  (ISO)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dibromophenyl 2,4,5-tribromophenyl ether  (ISO)
2-butoxyethanol  (ISO)
2-hydroxyethyl methacrylate  (EXP)
2-palmitoylglycerol  (EXP)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3,3',5-triiodo-L-thyronine  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4-amino-2,6-dinitrotoluene  (ISO)
acrylamide  (ISO)
aflatoxin B1  (EXP,ISO)
Aflatoxin B2 alpha  (EXP)
Aflatoxin G1  (EXP)
Aflatoxin G2  (EXP)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
aristolochic acid A  (EXP)
arsane  (EXP)
arsenic atom  (EXP)
azathioprine  (EXP)
beauvericin  (EXP)
benzo[a]pyrene  (EXP,ISO)
benzo[b]fluoranthene  (ISO)
benzo[e]pyrene  (EXP)
beta-lapachone  (EXP)
beta-naphthoflavone  (EXP,ISO)
bilirubin IXalpha  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
bortezomib  (EXP,ISO)
bromobenzene  (ISO)
buta-1,3-diene  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
calcitriol  (EXP)
captan  (ISO)
carbon nanotube  (ISO)
carbonyl sulfide  (ISO)
CGP 52608  (EXP)
chloroacetaldehyde  (EXP)
chloropicrin  (EXP)
chloroprene  (ISO)
chloroquine  (ISO)
chromium(6+)  (EXP)
cidofovir anhydrous  (EXP)
cisplatin  (EXP)
clodronic acid  (EXP)
cobalt dichloride  (EXP,ISO)
copper atom  (EXP)
copper(0)  (EXP)
copper(II) chloride  (EXP)
copper(II) sulfate  (EXP)
corn oil  (ISO)
cyclosporin A  (EXP,ISO)
decabromodiphenyl ether  (ISO)
diethyl malate  (EXP)
diethyl maleate  (EXP)
dioxygen  (EXP)
endosulfan  (ISO)
enniatin  (EXP)
epoxiconazole  (ISO)
fenofibrate  (ISO)
fenthion  (ISO)
fentin chloride  (ISO)
ferric oxide  (ISO)
fluoranthene  (ISO)
flutamide  (ISO)
folic acid  (ISO)
folpet  (ISO)
fulvestrant  (EXP)
furan  (ISO)
genistein  (EXP)
gentamycin  (ISO)
gold atom  (EXP)
gold(0)  (EXP)
GW 4064  (ISO)
hydrogen peroxide  (EXP)
ifosfamide  (EXP)
inulin  (ISO)
lead diacetate  (EXP)
leflunomide  (ISO)
Licochalcone B  (EXP)
lipopolysaccharide  (EXP)
LY294002  (EXP)
menadione  (EXP)
mercury dichloride  (ISO)
metformin  (ISO)
methamphetamine  (ISO)
methapyrilene  (EXP)
methylmercury chloride  (ISO)
mono(2-ethylhexyl) phthalate  (ISO)
N-acetyl-L-cysteine  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
naphthalene  (ISO)
nevirapine  (ISO)
nitrofen  (ISO)
ochratoxin A  (EXP)
orphenadrine  (ISO)
oxycodone  (ISO)
ozone  (ISO)
paracetamol  (EXP,ISO)
perfluorohexanesulfonic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
permethrin  (ISO)
phenformin  (ISO)
phenobarbital  (ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
propanal  (EXP)
propiconazole  (ISO)
quercetin  (ISO)
quinolin-8-ol  (EXP)
rotenone  (ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
SB 203580  (ISO)
sevoflurane  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (EXP,ISO)
silver(0)  (EXP,ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP)
sodium dichromate  (ISO)
sotorasib  (EXP)
sulforaphane  (EXP)
sunitinib  (EXP)
tamoxifen  (ISO)
temozolomide  (EXP)
tert-butyl hydroperoxide  (EXP)
testosterone  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
thiram  (EXP)
trametinib  (EXP)
trichloroethene  (ISO)
triphenyl phosphate  (EXP)
triptonide  (ISO)
troglitazone  (ISO)
urethane  (EXP)
valdecoxib  (ISO)
valproic acid  (EXP,ISO)
vinclozolin  (ISO)
zearalenone  (EXP)
zinc atom  (EXP)
zinc(0)  (EXP)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process

Molecular Function

References

References - curated
# Reference Title Reference Citation
1. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
2. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
Additional References at PubMed
PMID:8889548   PMID:11459809   PMID:12374686   PMID:12477932   PMID:14570898   PMID:15489334   PMID:16924236   PMID:17192422   PMID:18499678   PMID:18597759   PMID:19578798   PMID:19851296  
PMID:20198315   PMID:20307321   PMID:21737788   PMID:21873635   PMID:22658674   PMID:22912861   PMID:24417816   PMID:24786516   PMID:25416956   PMID:25640309   PMID:26186194   PMID:27229929  
PMID:28514442   PMID:28548877   PMID:29180628   PMID:31515488   PMID:31945190   PMID:31996062   PMID:32047918   PMID:32296183   PMID:33961781   PMID:37646890   PMID:39260748  


Genomics

Comparative Map Data
OSGIN1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381683,953,240 - 83,966,332 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1683,931,311 - 83,966,332 (+)EnsemblGRCh38hg38GRCh38
GRCh371683,986,845 - 83,999,937 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361682,540,173 - 82,557,438 (+)NCBINCBI36Build 36hg18NCBI36
Celera1668,283,632 - 68,302,337 (+)NCBICelera
Cytogenetic Map16q23.3NCBI
HuRef1669,737,904 - 69,751,578 (+)NCBIHuRef
CHM1_11685,398,355 - 85,411,465 (+)NCBICHM1_1
T2T-CHM13v2.01690,019,300 - 90,032,388 (+)NCBIT2T-CHM13v2.0
Osgin1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398120,160,874 - 120,172,996 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl8120,160,863 - 120,172,995 (+)EnsemblGRCm39 Ensembl
GRCm388119,425,882 - 119,446,257 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8119,434,124 - 119,446,256 (+)EnsemblGRCm38mm10GRCm38
MGSCv378121,961,062 - 121,970,156 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv368122,323,139 - 122,332,233 (+)NCBIMGSCv36mm8
Celera8123,654,251 - 123,663,345 (+)NCBICelera
Cytogenetic Map8E1NCBI
cM Map867.71NCBI
Osgin1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr81964,380,336 - 64,409,165 (+)NCBIGRCr8
mRatBN7.21947,471,750 - 47,500,517 (+)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl1947,492,171 - 47,500,516 (+)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx1954,279,628 - 54,294,893 (+)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.01954,960,419 - 54,975,701 (+)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.01957,173,810 - 57,189,105 (+)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.01952,056,808 - 52,085,491 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1952,077,109 - 52,085,496 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01962,818,232 - 62,834,031 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41949,675,215 - 49,690,479 (+)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.11949,680,095 - 49,695,359 (+)NCBI
Celera1946,744,527 - 46,759,791 (+)NCBICelera
Cytogenetic Map19q12NCBI
OSGIN1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21893,679,420 - 93,714,857 (+)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11699,596,537 - 99,631,845 (+)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01664,555,632 - 64,590,930 (+)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11683,942,912 - 83,978,111 (+)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1683,942,912 - 83,978,111 (+)Ensemblpanpan1.1panPan2
OSGIN1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1568,344,406 - 68,377,842 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha568,358,285 - 68,392,074 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.0568,642,665 - 68,676,414 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl568,642,008 - 68,676,232 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.1568,590,364 - 68,624,216 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.0568,426,772 - 68,460,641 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.0568,842,573 - 68,876,492 (-)NCBIUU_Cfam_GSD_1.0
Osgin1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440934928,050,244 - 28,075,053 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_0049366413,803,767 - 3,813,041 (-)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_0049366413,803,799 - 3,812,995 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OSGIN1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl64,642,764 - 4,653,487 (-)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.164,642,762 - 4,656,113 (-)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
OSGIN1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1569,365,072 - 69,378,319 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl569,365,096 - 69,378,319 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660476,409,526 - 6,422,520 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Osgin1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247463,577,184 - 3,610,079 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in OSGIN1
35 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 16q23.1-24.3(chr16:78816291-90081985)x3 copy number gain See cases [RCV000050840] Chr16:78816291..90081985 [GRCh38]
Chr16:78850188..90148393 [GRCh37]
Chr16:77407689..88675894 [NCBI36]
Chr16:16q23.1-24.3		 pathogenic
GRCh38/hg38 16q23.3-24.2(chr16:83878992-87223838)x1 copy number loss See cases [RCV000051122] Chr16:83878992..87223838 [GRCh38]
Chr16:83912597..87257444 [GRCh37]
Chr16:82470098..85814945 [NCBI36]
Chr16:16q23.3-24.2		 pathogenic
GRCh38/hg38 16q22.1-24.3(chr16:70514631-90081985)x3 copy number gain See cases [RCV000052422] Chr16:70514631..90081985 [GRCh38]
Chr16:70548534..90148393 [GRCh37]
Chr16:69106035..88675894 [NCBI36]
Chr16:16q22.1-24.3		 pathogenic
GRCh38/hg38 16q21-24.3(chr16:65313395-90081985)x3 copy number gain See cases [RCV000052421] Chr16:65313395..90081985 [GRCh38]
Chr16:65347298..90148393 [GRCh37]
Chr16:63904799..88675894 [NCBI36]
Chr16:16q21-24.3		 pathogenic
GRCh38/hg38 16q23.1-24.3(chr16:76873569-90081985)x3 copy number gain See cases [RCV000052423] Chr16:76873569..90081985 [GRCh38]
Chr16:76907466..90148393 [GRCh37]
Chr16:75464967..88675894 [NCBI36]
Chr16:16q23.1-24.3		 pathogenic
GRCh38/hg38 16q23.3-24.3(chr16:82173150-90081985)x3 copy number gain See cases [RCV000052424] Chr16:82173150..90081985 [GRCh38]
Chr16:82206755..90148393 [GRCh37]
Chr16:80764256..88675894 [NCBI36]
Chr16:16q23.3-24.3		 pathogenic
GRCh38/hg38 16q23.1-24.2(chr16:78704275-87819342)x1 copy number loss See cases [RCV000053359] Chr16:78704275..87819342 [GRCh38]
Chr16:78738172..87852948 [GRCh37]
Chr16:77295673..86410449 [NCBI36]
Chr16:16q23.1-24.2		 pathogenic
GRCh38/hg38 16q23.3-24.1(chr16:81753762-85714791)x1 copy number loss See cases [RCV000053360] Chr16:81753762..85714791 [GRCh38]
Chr16:81787367..85748397 [GRCh37]
Chr16:80344868..84305898 [NCBI36]
Chr16:16q23.3-24.1		 pathogenic
GRCh38/hg38 16q23.3(chr16:83602431-84024341)x3 copy number gain See cases [RCV000053935] Chr16:83602431..84024341 [GRCh38]
Chr16:83636036..84057946 [GRCh37]
Chr16:82193537..82615447 [NCBI36]
Chr16:16q23.3		 uncertain significance
GRCh38/hg38 16q23.3-24.1(chr16:83016872-85087809)x1 copy number loss See cases [RCV000053361] Chr16:83016872..85087809 [GRCh38]
Chr16:83050477..85121415 [GRCh37]
Chr16:81607978..83678916 [NCBI36]
Chr16:16q23.3-24.1		 pathogenic
GRCh38/hg38 16q23.3(chr16:83796168-84063463)x3 copy number gain See cases [RCV000053936] Chr16:83796168..84063463 [GRCh38]
Chr16:83829773..84097068 [GRCh37]
Chr16:82387274..82654569 [NCBI36]
Chr16:16q23.3		 uncertain significance
NM_182981.2(OSGIN1):c.657C>T (p.Leu219=) single nucleotide variant Malignant melanoma [RCV000071252] Chr16:83965230 [GRCh38]
Chr16:83998835 [GRCh37]
Chr16:82556336 [NCBI36]
Chr16:16q23.3		 not provided
GRCh38/hg38 16q22.1-24.1(chr16:70414573-84908120)x1 copy number loss See cases [RCV000133814] Chr16:70414573..84908120 [GRCh38]
Chr16:70448476..84941726 [GRCh37]
Chr16:69005977..83499227 [NCBI36]
Chr16:16q22.1-24.1		 pathogenic
GRCh38/hg38 16q23.3-24.1(chr16:83399060-84908120)x1 copy number loss See cases [RCV000133929] Chr16:83399060..84908120 [GRCh38]
Chr16:83432665..84941726 [GRCh37]
Chr16:81990166..83499227 [NCBI36]
Chr16:16q23.3-24.1		 pathogenic
GRCh38/hg38 16q23.3-24.1(chr16:83878992-84908120)x3 copy number gain See cases [RCV000135758] Chr16:83878992..84908120 [GRCh38]
Chr16:83912597..84941726 [GRCh37]
Chr16:82470098..83499227 [NCBI36]
Chr16:16q23.3-24.1		 pathogenic|uncertain significance
GRCh38/hg38 16q21-24.1(chr16:62925929-84585795)x3 copy number gain See cases [RCV000135863] Chr16:62925929..84585795 [GRCh38]
Chr16:62959833..84619401 [GRCh37]
Chr16:61517334..83176902 [NCBI36]
Chr16:16q21-24.1		 pathogenic
GRCh38/hg38 16q23.3-24.1(chr16:83687650-86073240)x1 copy number loss See cases [RCV000136504] Chr16:83687650..86073240 [GRCh38]
Chr16:83721255..86106846 [GRCh37]
Chr16:82278756..84664347 [NCBI36]
Chr16:16q23.3-24.1		 pathogenic
GRCh38/hg38 16q23.2-24.3(chr16:80946659-90081985)x3 copy number gain See cases [RCV000136898] Chr16:80946659..90081985 [GRCh38]
Chr16:80980556..90148393 [GRCh37]
Chr16:79538057..88675894 [NCBI36]
Chr16:16q23.2-24.3		 pathogenic|likely pathogenic
GRCh38/hg38 16q22.1-24.3(chr16:70749398-90096995)x3 copy number gain See cases [RCV000137495] Chr16:70749398..90096995 [GRCh38]
Chr16:70783301..90163403 [GRCh37]
Chr16:69340802..88690904 [NCBI36]
Chr16:16q22.1-24.3		 pathogenic
GRCh38/hg38 16q23.3-24.3(chr16:83478453-89932910)x3 copy number gain See cases [RCV000137980] Chr16:83478453..89932910 [GRCh38]
Chr16:83512058..89999318 [GRCh37]
Chr16:82069559..88526819 [NCBI36]
Chr16:16q23.3-24.3		 likely pathogenic
GRCh38/hg38 16q23.3(chr16:83478453-84036483)x3 copy number gain See cases [RCV000138549] Chr16:83478453..84036483 [GRCh38]
Chr16:83512058..84070088 [GRCh37]
Chr16:82069559..82627589 [NCBI36]
Chr16:16q23.3		 uncertain significance
GRCh38/hg38 16q21-24.3(chr16:65511483-90096995)x3 copy number gain See cases [RCV000139426] Chr16:65511483..90096995 [GRCh38]
Chr16:65545386..90163403 [GRCh37]
Chr16:64102887..88690904 [NCBI36]
Chr16:16q21-24.3		 pathogenic
GRCh38/hg38 16q23.3-24.1(chr16:83763804-84558035)x1 copy number loss See cases [RCV000139413] Chr16:83763804..84558035 [GRCh38]
Chr16:83797409..84591641 [GRCh37]
Chr16:82354910..83149142 [NCBI36]
Chr16:16q23.3-24.1		 likely pathogenic|uncertain significance
GRCh38/hg38 16q23.1-24.3(chr16:75377981-90081992)x3 copy number gain See cases [RCV000139302] Chr16:75377981..90081992 [GRCh38]
Chr16:75411879..90148400 [GRCh37]
Chr16:73969380..88675901 [NCBI36]
Chr16:16q23.1-24.3		 pathogenic
GRCh38/hg38 16q23.2-24.3(chr16:80717291-90096662)x3 copy number gain See cases [RCV000141128] Chr16:80717291..90096662 [GRCh38]
Chr16:80751188..90163070 [GRCh37]
Chr16:79308689..88690571 [NCBI36]
Chr16:16q23.2-24.3		 pathogenic
GRCh38/hg38 16q23.1-24.3(chr16:76336203-90088654)x3 copy number gain See cases [RCV000141700] Chr16:76336203..90088654 [GRCh38]
Chr16:76370100..90155062 [GRCh37]
Chr16:74927601..88682563 [NCBI36]
Chr16:16q23.1-24.3		 pathogenic
GRCh38/hg38 16q21-24.3(chr16:64389378-90081985)x3 copy number gain See cases [RCV000142578] Chr16:64389378..90081985 [GRCh38]
Chr16:64423281..90148393 [GRCh37]
Chr16:62980782..88675894 [NCBI36]
Chr16:16q21-24.3		 pathogenic|likely pathogenic
GRCh38/hg38 16q12.2-24.3(chr16:52899183-90088654)x3 copy number gain See cases [RCV000143425] Chr16:52899183..90088654 [GRCh38]
Chr16:52933095..90155062 [GRCh37]
Chr16:51490596..88682563 [NCBI36]
Chr16:16q12.2-24.3		 pathogenic
GRCh37/hg19 16q23.1-24.3(chr16:74872514-90274440)x3 copy number gain See cases [RCV000240108] Chr16:74872514..90274440 [GRCh37]
Chr16:16q23.1-24.3		 pathogenic
t(5;16)(p15.31;q23.1) translocation not provided [RCV000203391] Chr5:1..8180513 [GRCh37]
Chr16:76935310..90354753 [GRCh37]
Chr5:5p15.33-15.31
Chr16:16q23.1-24.3		 likely pathogenic
GRCh37/hg19 16q11.2-24.3(chr16:46615804-90142285)x1 copy number loss Breast ductal adenocarcinoma [RCV000207138] Chr16:46615804..90142285 [GRCh37]
Chr16:16q11.2-24.3		 uncertain significance
GRCh37/hg19 16q22.2-24.3(chr16:72107834-90142285)x1 copy number loss Breast ductal adenocarcinoma [RCV000207182] Chr16:72107834..90142285 [GRCh37]
Chr16:16q22.2-24.3		 uncertain significance
Single allele complex Breast ductal adenocarcinoma [RCV000207314] Chr16:56368689..90141355 [GRCh37]
Chr16:16q12.2-24.3		 uncertain significance
GRCh37/hg19 16q23.3-24.1(chr16:83496909-84695933)x1 copy number loss See cases [RCV000240561] Chr16:83496909..84695933 [GRCh37]
Chr16:16q23.3-24.1		 uncertain significance
GRCh37/hg19 16q11.2-24.3(chr16:46464488-90155062)x3 copy number gain See cases [RCV000446110] Chr16:46464488..90155062 [GRCh37]
Chr16:16q11.2-24.3		 pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:69193-90274381)x3 copy number gain See cases [RCV000446684] Chr16:69193..90274381 [GRCh37]
Chr16:16p13.3-q24.3		 pathogenic
GRCh37/hg19 16q23.3(chr16:83998698-84024074)x1 copy number loss See cases [RCV000447766] Chr16:83998698..84024074 [GRCh37]
Chr16:16q23.3		 likely benign
GRCh37/hg19 16q23.3(chr16:83986845-84014686)x3 copy number gain See cases [RCV000447928] Chr16:83986845..84014686 [GRCh37]
Chr16:16q23.3		 benign|likely benign
GRCh37/hg19 16q23.3(chr16:83903257-84174323)x1 copy number loss See cases [RCV000510687] Chr16:83903257..84174323 [GRCh37]
Chr16:16q23.3		 likely benign
GRCh37/hg19 16q23.3-24.1(chr16:83926471-84215425)x1 copy number loss See cases [RCV000510184] Chr16:83926471..84215425 [GRCh37]
Chr16:16q23.3-24.1		 uncertain significance
GRCh37/hg19 16p13.2-q24.3(chr16:9273328-89548493)x3 copy number gain See cases [RCV000511622] Chr16:9273328..89548493 [GRCh37]
Chr16:16p13.2-q24.3		 uncertain significance
GRCh37/hg19 16q11.2-24.3(chr16:46497599-90354753)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626429] Chr16:46497599..90354753 [GRCh37]
Chr16:16q11.2-24.3		 drug response
GRCh37/hg19 16p13.3-q24.3(chr16:85881-90155062)x3 copy number gain See cases [RCV000512138] Chr16:85881..90155062 [GRCh37]
Chr16:16p13.3-q24.3		 pathogenic
GRCh37/hg19 16q11.2-24.3(chr16:46455960-90354753)x1 copy number loss Poly (ADP-Ribose) polymerase inhibitor response [RCV000626435] Chr16:46455960..90354753 [GRCh37]
Chr16:16q11.2-24.3		 drug response
GRCh37/hg19 16q13-24.3(chr16:57051473-89797669)x3 copy number gain See cases [RCV000512511] Chr16:57051473..89797669 [GRCh37]
Chr16:16q13-24.3		 pathogenic
GRCh37/hg19 16q23.3-24.3(chr16:83001540-90155062)x3 copy number gain See cases [RCV000512468] Chr16:83001540..90155062 [GRCh37]
Chr16:16q23.3-24.3		 likely pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:85881-90155062) copy number gain See cases [RCV000511296] Chr16:85881..90155062 [GRCh37]
Chr16:16p13.3-q24.3		 pathogenic
GRCh37/hg19 16q23.3(chr16:83253758-84134459)x1 copy number loss not provided [RCV000683850] Chr16:83253758..84134459 [GRCh37]
Chr16:16q23.3		 uncertain significance
GRCh37/hg19 16q23.2-24.3(chr16:79400436-90155062)x3 copy number gain not provided [RCV000683845] Chr16:79400436..90155062 [GRCh37]
Chr16:16q23.2-24.3		 pathogenic
GRCh37/hg19 16q22.2-24.3(chr16:72515938-90155062)x3 copy number gain not provided [RCV000683831] Chr16:72515938..90155062 [GRCh37]
Chr16:16q22.2-24.3		 pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:88165-90163275)x3 copy number gain not provided [RCV000738917] Chr16:88165..90163275 [GRCh37]
Chr16:16p13.3-q24.3		 pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:88165-90274695)x3 copy number gain not provided [RCV000738918] Chr16:88165..90274695 [GRCh37]
Chr16:16p13.3-q24.3		 pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:61451-90294632)x3 copy number gain not provided [RCV000738915] Chr16:61451..90294632 [GRCh37]
Chr16:16p13.3-q24.3		 pathogenic
GRCh37/hg19 16q23.3-24.1(chr16:83813294-84984350)x3 copy number gain not provided [RCV000739258] Chr16:83813294..84984350 [GRCh37]
Chr16:16q23.3-24.1		 likely benign
GRCh37/hg19 16q23.3(chr16:83935523-84057571)x1 copy number loss not provided [RCV000739260] Chr16:83935523..84057571 [GRCh37]
Chr16:16q23.3		 benign
NM_182981.3(OSGIN1):c.516C>T (p.Ala172=) single nucleotide variant not provided [RCV000968332] Chr16:83965089 [GRCh38]
Chr16:83998694 [GRCh37]
Chr16:16q23.3		 benign
NM_182981.3(OSGIN1):c.540G>A (p.Arg180=) single nucleotide variant not provided [RCV000904375] Chr16:83965113 [GRCh38]
Chr16:83998718 [GRCh37]
Chr16:16q23.3		 benign
GRCh37/hg19 16q23.3(chr16:83970585-84077491)x1 copy number loss not provided [RCV000845768] Chr16:83970585..84077491 [GRCh37]
Chr16:16q23.3		 uncertain significance
GRCh37/hg19 16q23.3(chr16:83904100-84058759)x1 copy number loss not provided [RCV000845885] Chr16:83904100..84058759 [GRCh37]
Chr16:16q23.3		 uncertain significance
GRCh37/hg19 16q23.2-24.1(chr16:79254648-84827672)x1 copy number loss not provided [RCV000849998] Chr16:79254648..84827672 [GRCh37]
Chr16:16q23.2-24.1		 uncertain significance
GRCh37/hg19 16q23.3-24.1(chr16:83330709-84866927)x1 copy number loss not provided [RCV001006830] Chr16:83330709..84866927 [GRCh37]
Chr16:16q23.3-24.1		 uncertain significance
GRCh37/hg19 16q23.3(chr16:83853228-84189313)x1 copy number loss not provided [RCV001006831] Chr16:83853228..84189313 [GRCh37]
Chr16:16q23.3		 uncertain significance
GRCh37/hg19 16q23.3(chr16:83903257-84057905)x1 copy number loss not provided [RCV001006832] Chr16:83903257..84057905 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.37A>C (p.Ser13Arg) single nucleotide variant not provided [RCV000963345] Chr16:83957708 [GRCh38]
Chr16:83991313 [GRCh37]
Chr16:16q23.3		 benign|likely benign
GRCh37/hg19 16q21-24.3(chr16:61524229-90155062)x3 copy number gain not provided [RCV001249359] Chr16:61524229..90155062 [GRCh37]
Chr16:16q21-24.3		 not provided
GRCh37/hg19 16q23.2-24.3(chr16:80386595-90163348)x3 copy number gain not provided [RCV001795551] Chr16:80386595..90163348 [GRCh37]
Chr16:16q23.2-24.3		 pathogenic
GRCh37/hg19 16q23.3-24.1(chr16:83313106-84608026) copy number loss not specified [RCV002052553] Chr16:83313106..84608026 [GRCh37]
Chr16:16q23.3-24.1		 uncertain significance
NC_000016.9:g.(?_83932750)_(84056514_?)del deletion Deficiency of malonyl-CoA decarboxylase [RCV001956536] Chr16:83932750..84056514 [GRCh37]
Chr16:16q23.3		 pathogenic
GRCh37/hg19 16q11.2-24.3(chr16:46503968-90155062)x3 copy number gain not provided [RCV002221458] Chr16:46503968..90155062 [GRCh37]
Chr16:16q11.2-24.3		 pathogenic
NC_000016.9:g.(?_83932750)_(84211465_?)dup duplication Primary ciliary dyskinesia [RCV003113901] Chr16:83932750..84211465 [GRCh37]
Chr16:16q23.3-24.1		 uncertain significance
GRCh37/hg19 16q22.2-24.3(chr16:71641395-90161959)x3 copy number gain Syndromic anorectal malformation [RCV002286607] Chr16:71641395..90161959 [GRCh37]
Chr16:16q22.2-24.3		 likely pathogenic
GRCh37/hg19 16q23.3(chr16:82943629-84073053)x3 copy number gain not provided [RCV002474827] Chr16:82943629..84073053 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.523A>G (p.Ile175Val) single nucleotide variant not specified [RCV004599550] Chr16:83965096 [GRCh38]
Chr16:83998701 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.913C>T (p.Arg305Cys) single nucleotide variant not specified [RCV004188308] Chr16:83965486 [GRCh38]
Chr16:83999091 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.940G>A (p.Ala314Thr) single nucleotide variant not specified [RCV004230862] Chr16:83965513 [GRCh38]
Chr16:83999118 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.1285G>A (p.Val429Met) single nucleotide variant not specified [RCV004217925] Chr16:83965858 [GRCh38]
Chr16:83999463 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.866T>A (p.Leu289His) single nucleotide variant not specified [RCV004136276] Chr16:83965439 [GRCh38]
Chr16:83999044 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.914G>A (p.Arg305His) single nucleotide variant not specified [RCV004135821] Chr16:83965487 [GRCh38]
Chr16:83999092 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.1059C>A (p.Ser353Arg) single nucleotide variant not specified [RCV004166454] Chr16:83965632 [GRCh38]
Chr16:83999237 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.743C>A (p.Thr248Lys) single nucleotide variant not specified [RCV004120362] Chr16:83965316 [GRCh38]
Chr16:83998921 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.388G>T (p.Ala130Ser) single nucleotide variant not specified [RCV004120290] Chr16:83960752 [GRCh38]
Chr16:83994357 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.755C>T (p.Pro252Leu) single nucleotide variant not specified [RCV004073507] Chr16:83965328 [GRCh38]
Chr16:83998933 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.299G>T (p.Gly100Val) single nucleotide variant not specified [RCV004129609] Chr16:83960663 [GRCh38]
Chr16:83994268 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.583G>A (p.Gly195Ser) single nucleotide variant not specified [RCV004128429] Chr16:83965156 [GRCh38]
Chr16:83998761 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.1089G>T (p.Arg363Ser) single nucleotide variant not specified [RCV004177543] Chr16:83965662 [GRCh38]
Chr16:83999267 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.403G>A (p.Glu135Lys) single nucleotide variant not specified [RCV004238478] Chr16:83960987 [GRCh38]
Chr16:83994592 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.1331C>T (p.Ala444Val) single nucleotide variant not specified [RCV004122492] Chr16:83965904 [GRCh38]
Chr16:83999509 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.1127T>G (p.Val376Gly) single nucleotide variant not specified [RCV004269232] Chr16:83965700 [GRCh38]
Chr16:83999305 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.371G>A (p.Arg124Gln) single nucleotide variant not specified [RCV004254375] Chr16:83960735 [GRCh38]
Chr16:83994340 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.232G>A (p.Glu78Lys) single nucleotide variant not specified [RCV004251566] Chr16:83960596 [GRCh38]
Chr16:83994201 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.676C>G (p.Leu226Val) single nucleotide variant not specified [RCV004282946] Chr16:83965249 [GRCh38]
Chr16:83998854 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.997C>A (p.Leu333Met) single nucleotide variant not specified [RCV004269233] Chr16:83965570 [GRCh38]
Chr16:83999175 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.494T>G (p.Leu165Arg) single nucleotide variant not specified [RCV004269704] Chr16:83965067 [GRCh38]
Chr16:83998672 [GRCh37]
Chr16:16q23.3		 uncertain significance
GRCh37/hg19 16q23.3(chr16:83853229-84046593)x1 copy number loss not provided [RCV003483299] Chr16:83853229..84046593 [GRCh37]
Chr16:16q23.3		 uncertain significance
GRCh37/hg19 16q23.3-24.1(chr16:83307393-84530337)x3 copy number gain not specified [RCV003987204] Chr16:83307393..84530337 [GRCh37]
Chr16:16q23.3-24.1		 uncertain significance
NM_182981.3(OSGIN1):c.31G>A (p.Ala11Thr) single nucleotide variant not specified [RCV004504515] Chr16:83957702 [GRCh38]
Chr16:83991307 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.334C>T (p.Arg112Trp) single nucleotide variant not specified [RCV004504516] Chr16:83960698 [GRCh38]
Chr16:83994303 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.821C>T (p.Ala274Val) single nucleotide variant not specified [RCV004504518] Chr16:83965394 [GRCh38]
Chr16:83998999 [GRCh37]
Chr16:16q23.3		 uncertain significance
GRCh37/hg19 16q23.3-24.3(chr16:82865402-90163542)x3 copy number gain not provided [RCV004577473] Chr16:82865402..90163542 [GRCh37]
Chr16:16q23.3-24.3		 pathogenic
NM_182981.3(OSGIN1):c.550G>A (p.Val184Ile) single nucleotide variant not specified [RCV004661892] Chr16:83965123 [GRCh38]
Chr16:83998728 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.826A>G (p.Thr276Ala) single nucleotide variant not specified [RCV004661893] Chr16:83965399 [GRCh38]
Chr16:83999004 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.1009T>C (p.Tyr337His) single nucleotide variant not specified [RCV004504513] Chr16:83965582 [GRCh38]
Chr16:83999187 [GRCh37]
Chr16:16q23.3		 uncertain significance
GRCh38/hg38 16q23.3-24.1(chr16:83763804-84276472)x3 copy number gain See cases [RCV000140831] Chr16:83763804..84276472 [GRCh38]
Chr16:83797409..84310078 [GRCh37]
Chr16:82354910..82867579 [NCBI36]
Chr16:16q23.3-24.1		 uncertain significance
GRCh38/hg38 16q23.2-24.3(chr16:80067315-90057871)x3 copy number gain See cases [RCV000142698] Chr16:80067315..90057871 [GRCh38]
Chr16:80101212..90124279 [GRCh37]
Chr16:78658713..88651780 [NCBI36]
Chr16:16q23.2-24.3		 pathogenic
GRCh37/hg19 16q23.3-24.1(chr16:83553094-86098013)x1 copy number loss See cases [RCV000203439] Chr16:83553094..86098013 [GRCh37]
Chr16:16q23.3-24.1		 likely pathogenic
GRCh37/hg19 16q23.3-24.3(chr16:82761333-90055381) copy number gain not provided [RCV000767619] Chr16:82761333..90055381 [GRCh37]
Chr16:16q23.3-24.3		 pathogenic
Single allele deletion Alveolar capillary dysplasia with pulmonary venous misalignment [RCV001251455] Chr16:83931797..86285776 [GRCh37]
Chr16:16q23.3-24.1		 likely pathogenic
GRCh37/hg19 16q23.3-24.1(chr16:83866931-85276940)x3 copy number gain not provided [RCV001258657] Chr16:83866931..85276940 [GRCh37]
Chr16:16q23.3-24.1		 uncertain significance
NM_182981.3(OSGIN1):c.772C>T (p.Pro258Ser) single nucleotide variant not specified [RCV004275578] Chr16:83965345 [GRCh38]
Chr16:83998950 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.1264G>A (p.Ala422Thr) single nucleotide variant not specified [RCV004504514] Chr16:83965837 [GRCh38]
Chr16:83999442 [GRCh37]
Chr16:16q23.3		 likely benign
NM_182981.3(OSGIN1):c.722A>G (p.Asn241Ser) single nucleotide variant not specified [RCV004504517] Chr16:83965295 [GRCh38]
Chr16:83998900 [GRCh37]
Chr16:16q23.3		 uncertain significance
NM_182981.3(OSGIN1):c.848C>T (p.Pro283Leu) single nucleotide variant not specified [RCV004504519] Chr16:83965421 [GRCh38]
Chr16:83999026 [GRCh37]
Chr16:16q23.3		 uncertain significance
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2183
Count of miRNA genes:769
Interacting mature miRNAs:931
Transcripts:ENST00000343939, ENST00000361711, ENST00000393306, ENST00000561552, ENST00000563543, ENST00000565123, ENST00000567707
Prediction methods:Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407172358GWAS821334_Halkaline phosphatase measurement QTL GWAS821334 (human)5e-10alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)168396596083965961Human
407169207GWAS818183_Hcervical cancer QTL GWAS818183 (human)0.000003cervical cancer168395796783957968Human
407331873GWAS980849_HIGF-1 measurement QTL GWAS980849 (human)2e-09IGF-1 measurementblood insulin-like growth factor 1 level (CMO:0001297)168395849783958498Human
407213795GWAS862771_Halkaline phosphatase measurement QTL GWAS862771 (human)6e-14alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)168396596083965961Human
407213794GWAS862770_Halkaline phosphatase measurement QTL GWAS862770 (human)5e-14alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)168395929083959291Human
407165007GWAS813983_Halkaline phosphatase measurement QTL GWAS813983 (human)1e-11alkaline phosphatase measurementblood alkaline phosphatase activity level (CMO:0000576)168395797583957976Human

Markers in Region
WI-15020  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371683,999,650 - 83,999,799UniSTSGRCh37
Build 361682,557,151 - 82,557,300RGDNCBI36
Celera1668,302,050 - 68,302,199RGD
Cytogenetic Map16q23.3UniSTS
HuRef1669,751,291 - 69,751,440UniSTS
GeneMap99-GB4 RH Map16467.94UniSTS
Whitehead-RH Map16329.9UniSTS
SHGC-147839  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371683,998,435 - 83,998,771UniSTSGRCh37
Build 361682,555,936 - 82,556,272RGDNCBI36
Celera1668,300,835 - 68,301,171RGD
Cytogenetic Map16q23.3UniSTS
HuRef1669,750,076 - 69,750,412UniSTS
TNG Radiation Hybrid Map1637834.0UniSTS


Expression

RNA-SEQ Expression

adipose tissue
alimentary part of gastrointestinal system
appendage
circulatory system
ectoderm
endocrine system
endoderm
entire extraembryonic component
exocrine system
hemolymphoid system
hepatobiliary system
integumental system
mesenchyme
mesoderm
musculoskeletal system
nervous system
pharyngeal arch
renal system
reproductive system
respiratory system
sensory system
visual system
1204 2439 2788 2249 4968 1726 2351 6 624 1933 465 2269 7292 6458 53 3728 1 852 1744 1617 174 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_029757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_182981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AC040169 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF191740 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF334780 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK290383 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY037158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY258066 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY258067 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY258068 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC020434 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC032476 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC093687 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC113417 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM976366 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068262 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HI573984 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HI573986 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HI573988 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Ensembl Acc Id: ENST00000343939
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1683,949,067 - 83,966,332 (+)Ensembl
Ensembl Acc Id: ENST00000361711   ⟹   ENSP00000355374
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1683,949,067 - 83,966,331 (+)Ensembl
Ensembl Acc Id: ENST00000393306   ⟹   ENSP00000376983
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1683,953,240 - 83,966,332 (+)Ensembl
Ensembl Acc Id: ENST00000563248
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1683,931,346 - 83,934,180 (+)Ensembl
Ensembl Acc Id: ENST00000563543
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1683,953,240 - 83,954,548 (+)Ensembl
Ensembl Acc Id: ENST00000565123   ⟹   ENSP00000462048
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1683,953,239 - 83,961,253 (+)Ensembl
Ensembl Acc Id: ENST00000566667
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1683,931,311 - 83,957,650 (+)Ensembl
Ensembl Acc Id: ENST00000567707   ⟹   ENSP00000457157
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1683,956,988 - 83,960,732 (+)Ensembl
RefSeq Acc Id: NM_182981   ⟹   NP_892026
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381683,953,240 - 83,966,332 (+)NCBI
Build 361682,544,328 - 82,557,438 (+)NCBI Archive
HuRef1669,737,904 - 69,751,578 (+)NCBI
CHM1_11685,398,355 - 85,411,465 (+)NCBI
T2T-CHM13v2.01690,019,300 - 90,032,388 (+)NCBI
Sequence:
RefSeq Acc Id: NP_892026   ⟸   NM_182981
- UniProtKB: Q96S88 (UniProtKB/Swiss-Prot),   Q86UQ1 (UniProtKB/Swiss-Prot),   Q52M33 (UniProtKB/Swiss-Prot),   Q9BZ70 (UniProtKB/Swiss-Prot),   Q9UJX0 (UniProtKB/Swiss-Prot)
- Sequence:
Ensembl Acc Id: ENSP00000355374   ⟸   ENST00000361711
Ensembl Acc Id: ENSP00000376983   ⟸   ENST00000393306
Ensembl Acc Id: ENSP00000462048   ⟸   ENST00000565123
Ensembl Acc Id: ENSP00000457157   ⟸   ENST00000567707

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-Q9UJX0-F1-model_v2 AlphaFold Q9UJX0 1-477 view protein structure

Promoters
RGD ID:6793350
Promoter ID:HG_KWN:24361
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:NM_182981
Position:
Human AssemblyChrPosition (strand)Source
Build 361682,544,094 - 82,544,594 (+)MPROMDB
RGD ID:7232993
Promoter ID:EPDNEW_H22243
Type:initiation region
Name:OSGIN1_1
Description:oxidative stress induced growth inhibitor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381683,953,240 - 83,953,300EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:30093 AgrOrtholog
COSMIC OSGIN1 COSMIC
Ensembl Genes ENSG00000140961 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000361711.7 UniProtKB/Swiss-Prot
  ENST00000393306 ENTREZGENE
  ENST00000393306.6 UniProtKB/Swiss-Prot
  ENST00000565123.5 UniProtKB/TrEMBL
  ENST00000567707.1 UniProtKB/TrEMBL
Gene3D-CATH 3.50.50.60 UniProtKB/Swiss-Prot
GTEx ENSG00000140961 GTEx
HGNC ID HGNC:30093 ENTREZGENE
Human Proteome Map OSGIN1 Human Proteome Map
InterPro FAD/NAD-bd_sf UniProtKB/Swiss-Prot
  OKL38_fam UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:29948 UniProtKB/Swiss-Prot
NCBI Gene 29948 ENTREZGENE
OMIM 607975 OMIM
PANTHER PTHR15192 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR15192:SF15 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA162398489 PharmGKB
Superfamily-SCOP SSF51905 UniProtKB/Swiss-Prot
UniProt H3BTF9_HUMAN UniProtKB/TrEMBL
  J3KRK7_HUMAN UniProtKB/TrEMBL
  OSGI1_HUMAN UniProtKB/Swiss-Prot
  Q52M33 ENTREZGENE
  Q86UQ1 ENTREZGENE
  Q96S88 ENTREZGENE
  Q9BZ70 ENTREZGENE
  Q9UJX0 ENTREZGENE
UniProt Secondary Q52M33 UniProtKB/Swiss-Prot
  Q86UQ1 UniProtKB/Swiss-Prot
  Q96S88 UniProtKB/Swiss-Prot
  Q9BZ70 UniProtKB/Swiss-Prot