NFKBIA (NFKB inhibitor alpha) - Rat Genome Database

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Gene: NFKBIA (NFKB inhibitor alpha) Homo sapiens
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Symbol: NFKBIA
Name: NFKB inhibitor alpha
RGD ID: 735440
HGNC Page HGNC
Description: Enables several functions, including NF-kappaB binding activity; nuclear localization sequence binding activity; and ubiquitin protein ligase binding activity. Involved in several processes, including negative regulation of macrophage derived foam cell differentiation; positive regulation of cholesterol efflux; and regulation of transcription, DNA-templated. Acts upstream of or within negative regulation of NF-kappaB transcription factor activity. Located in cytosol; nucleus; and plasma membrane. Implicated in several diseases, including childhood-onset asthma; hematologic cancer (multiple); hepatitis B; hepatitis C; and lung disease (multiple). Biomarker of nephrotic syndrome; prostate adenocarcinoma; prostate cancer; and pulmonary tuberculosis.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: EDAID2; I-kappa-B-alpha; IkappaBalpha; ikB-alpha; IKBA; MAD-3; major histocompatibility complex enhancer-binding protein MAD3; NF-kappa-B inhibitor alpha; NFKBI; nuclear factor of kappa light chain gene enhancer in B-cells; nuclear factor of kappa light chain gene enhancer in b-cells inhibitor, alpha; nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1435,401,513 - 35,404,749 (-)EnsemblGRCh38hg38GRCh38
GRCh381435,401,513 - 35,404,749 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371435,870,719 - 35,873,955 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361434,940,468 - 34,943,695 (-)NCBINCBI36hg18NCBI36
Build 341434,940,467 - 34,943,695NCBI
Celera1415,734,587 - 15,737,850 (-)NCBI
Cytogenetic Map14q13.2NCBI
HuRef1415,984,422 - 15,987,685 (-)NCBIHuRef
CHM1_11435,870,469 - 35,873,713 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model