Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: PLEKHA7 (pleckstrin homology domain containing A7) Homo sapiens
Analyze
Symbol: PLEKHA7
Name: pleckstrin homology domain containing A7
Description: Exhibits delta-catenin binding activity. Involved in epithelial cell-cell adhesion; pore complex assembly; and zonula adherens maintenance. Localizes to several cellular components, including centrosome; pore complex; and zonula adherens; PARTICIPATES IN E-cadherin signaling pathway; INTERACTS WITH (-)-epigallocatechin 3-gallate; 17beta-estradiol; 2,3,7,8-tetrachlorodibenzodioxine.
Type: protein-coding
RefSeq Status: VALIDATED
Also known as: DKFZp686M22243; PH domain-containing family A member 7; pleckstrin homology domain containing, family A member 2; pleckstrin homology domain containing, family A member 7; pleckstrin homology domain-containing family A member 6; pleckstrin homology domain-containing family A member 7
Orthologs:
Mus musculus (house mouse) : Plekha7 (pleckstrin homology domain containing, family A member 7)  MGI  Alliance
Rattus norvegicus (Norway rat) : Plekha7 (pleckstrin homology domain containing A7)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Plekha7 (pleckstrin homology domain containing A7)
Pan paniscus (bonobo/pygmy chimpanzee) : PLEKHA7 (pleckstrin homology domain containing A7)
Canis lupus familiaris (dog) : PLEKHA7 (pleckstrin homology domain containing A7)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Plekha7 (pleckstrin homology domain containing A7)
Sus scrofa (pig) : PLEKHA7 (pleckstrin homology domain containing A7)
Chlorocebus sabaeus (African green monkey) : PLEKHA7 (pleckstrin homology domain containing A7)
Heterocephalus glaber (naked mole-rat) : Plekha7 (pleckstrin homology domain containing A7)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1116,777,297 - 17,014,414 (-)EnsemblGRCh38hg38GRCh38
GRCh381116,777,297 - 17,014,423 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371116,809,207 - 17,035,963 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361116,765,786 - 16,992,535 (-)NCBINCBI36hg18NCBI36
Build 341116,765,787 - 16,992,535NCBI
Celera1116,936,331 - 17,162,547 (-)NCBI
Cytogenetic Map11p15.2-p15.1NCBI
HuRef1116,493,736 - 16,718,829 (-)NCBIHuRef
CHM1_11116,808,365 - 17,035,019 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on PLEKHA7
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1350975
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.