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Gene: CAV1 (caveolin 1) Homo sapiens
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Symbol: CAV1
Name: caveolin 1
Description: Exhibits several functions, including enzyme binding activity; inward rectifier potassium channel inhibitor activity; and ion channel binding activity. Involved in several processes, including endocytosis; regulation of cellular protein metabolic process; and regulation of signal transduction. Localizes to several cellular components, including the Golgi membrane; basolateral plasma membrane; and caveola. Colocalizes with the focal adhesion. Implicated in several diseases, including breast cancer (multiple); lipodystrophy (multiple); primary open angle glaucoma; primary pulmonary hypertension; and systemic scleroderma (multiple). Biomarker of several diseases, including acoustic neuroma; breast cancer (multiple); carcinoma (multiple); pulmonary hypertension; and systemic scleroderma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BSCL3; CAV; caveolin 1, caveolae protein, 22kDa; caveolin-1; cell growth-inhibiting protein 32; CGL3; LCCNS; MSTP085; PPH3; VIP21
Orthologs:
Mus musculus (house mouse) : Cav1 (caveolin 1, caveolae protein)  MGI  Alliance
Rattus norvegicus (Norway rat) : Cav1 (caveolin 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Cav1 (caveolin 1)
Pan paniscus (bonobo/pygmy chimpanzee) : CAV1 (caveolin 1)
Canis lupus familiaris (dog) : CAV1 (caveolin 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Cav1 (caveolin 1)
Sus scrofa (pig) : CAV1 (caveolin 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh387116,525,009 - 116,561,185 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh377116,164,839 - 116,201,239 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 367115,952,075 - 115,988,466 (+)NCBINCBI36hg18NCBI36
Build 347115,758,789 - 115,795,181NCBI
Celera7110,972,249 - 111,008,654 (+)NCBI
Cytogenetic Map7q31.2NCBI
HuRef7110,530,835 - 110,566,784 (+)NCBIHuRef
CHM1_17116,098,482 - 116,134,827 (+)NCBICHM1_1
CRA_TCAGchr7v27115,560,275 - 115,596,679 (+)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
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References - uncurated

Genomics

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Expression


Sequence

Nucleotide Sequences
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