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Gene: ATP2B1 (ATPase plasma membrane Ca2+ transporting 1) Homo sapiens
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Symbol: ATP2B1
Name: ATPase plasma membrane Ca2+ transporting 1
Description: Exhibits ATPase activity and calcium-transporting ATPase activity involved in regulation of presynaptic cytosolic calcium ion concentration. Involved in calcium ion export across plasma membrane; negative regulation of cytosolic calcium ion concentration; and regulation of cellular response to insulin stimulus. Localizes to several cellular components, including the GABA-ergic synapse; glutamatergic synapse; and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATPase, Ca++ transporting, plasma membrane 1; plasma membrane calcium ATPase; plasma membrane calcium pump; plasma membrane calcium-ATPase; plasma membrane calcium-transporting ATPase 1; PMCA1; PMCA1kb
Orthologs:
Mus musculus (house mouse) : Atp2b1 (ATPase, Ca++ transporting, plasma membrane 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Atp2b1 (ATPase plasma membrane Ca2+ transporting 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Atp2b1 (ATPase plasma membrane Ca2+ transporting 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ATP2B1 (ATPase plasma membrane Ca2+ transporting 1)
Canis lupus familiaris (dog) : ATP2B1 (ATPase plasma membrane Ca2+ transporting 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Atp2b1 (ATPase plasma membrane Ca2+ transporting 1)
Sus scrofa (pig) : ATP2B1 (ATPase plasma membrane Ca2+ transporting 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38 Ensembl1289,588,049 - 89,709,300 (-)Ensembl
GRCh381289,588,049 - 89,709,366 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371289,981,826 - 90,103,130 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361288,505,957 - 88,573,975 (-)NCBINCBI36hg18NCBI36
Build 341288,484,295 - 88,552,312NCBI
Celera1289,653,490 - 89,721,509 (-)NCBI
Cytogenetic Map12q21.33NCBI
HuRef1287,047,680 - 87,115,698 (-)NCBIHuRef
CHM1_11289,946,885 - 90,014,891 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression

RNA-SEQ Expression

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ATP2B1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 732984
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2020-01-07
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.