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Gene: ROBO1 (roundabout guidance receptor 1) Homo sapiens
Symbol: ROBO1
Name: roundabout guidance receptor 1
Description: Exhibits LRR domain binding activity and identical protein binding activity. Involved in several processes, including cell migration involved in sprouting angiogenesis; generation of neurons; and regulation of signal transduction. Localizes to cell surface; cytoplasm; and plasma membrane.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: deleted in U twenty twenty; DUTT1; FLJ21882; MGC131599; MGC133277; roundabout homolog 1; roundabout homolog 1 (drosophila); roundabout, axon guidance receptor, homolog 1; SAX3
Mus musculus (house mouse) : Robo1 (roundabout guidance receptor 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Robo1 (roundabout guidance receptor 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Robo1 (roundabout guidance receptor 1)
Pan paniscus (bonobo/pygmy chimpanzee) : ROBO1 (roundabout guidance receptor 1)
Canis lupus familiaris (dog) : ROBO1 (roundabout guidance receptor 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Robo1 (roundabout guidance receptor 1)
Sus scrofa (pig) : ROBO1 (roundabout guidance receptor 1)
Chlorocebus sabaeus (African green monkey) : ROBO1 (roundabout guidance receptor 1)
Heterocephalus glaber (naked mole-rat) : Robo1 (roundabout guidance receptor 1)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl378,597,239 - 79,767,998 (-)EnsemblGRCh38hg38GRCh38
GRCh38378,597,238 - 79,767,998 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37378,646,388 - 79,817,059 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36378,729,080 - 79,721,751 (-)NCBINCBI36hg18NCBI36
Build 34378,729,079 - 79,721,751NCBI
Celera379,390,331 - 80,561,510 (-)NCBI
Cytogenetic Map3p12.3NCBI
HuRef378,666,127 - 79,837,569 (-)NCBIHuRef
CHM1_1378,599,244 - 79,770,223 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on ROBO1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735617
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.