SERPINE1 Human (+)-catechin multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [Catechin results in decreased expression of SERPINE1 mRNA] and U 0126 inhibits the reaction [Catechin results in decreased expression of SERPINE1 mRNA] CTD PMID:17379280 SERPINE1 Human (+)-catechin decreases expression EXP 6480464 Catechin results in decreased expression of SERPINE1 mRNA CTD PMID:17379280 SERPINE1 Human (R)-adrenaline increases expression ISO Serpine1 (Mus musculus) 6480464 Epinephrine results in increased expression of SERPINE1 mRNA CTD PMID:15850565 SERPINE1 Human (R)-lipoic acid multiple interactions ISO Serpine1 (Mus musculus) 6480464 Thioctic Acid inhibits the reaction [Silicon results in increased expression of SERPINE1 protein] CTD PMID:34252510 SERPINE1 Human (R)-noradrenaline increases expression ISO Serpine1 (Mus musculus) 6480464 Norepinephrine results in increased expression of SERPINE1 mRNA CTD PMID:17429342 SERPINE1 Human (S)-colchicine increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Colchicine results in increased expression of SERPINE1 mRNA CTD PMID:20624997 SERPINE1 Human (S)-naringenin multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 naringenin inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA] CTD PMID:22709785 SERPINE1 Human (S)-nicotine increases secretion ISO Serpine1 (Rattus norvegicus) 6480464 Nicotine results in increased secretion of SERPINE1 protein CTD PMID:21596853 SERPINE1 Human (S)-nicotine increases expression EXP 6480464 Nicotine results in increased expression of SERPINE1 mRNA CTD PMID:11166759 SERPINE1 Human 1,1-dichloroethene increases expression ISO Serpine1 (Mus musculus) 6480464 vinylidene chloride results in increased expression of SERPINE1 mRNA CTD PMID:26682919 SERPINE1 Human 1,10-phenanthroline increases expression EXP 6480464 1 and 10-phenanthroline results in increased expression of SERPINE1 mRNA CTD PMID:19502547 SERPINE1 Human 1,2,4-trimethylbenzene increases expression ISO Serpine1 (Rattus norvegicus) 6480464 pseudocumene results in increased expression of SERPINE1 protein CTD PMID:17337753 SERPINE1 Human 1,2-dimethylhydrazine increases expression ISO Serpine1 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of SERPINE1 mRNA CTD PMID:22206623 SERPINE1 Human 1-chloro-2,4-dinitrobenzene affects expression EXP 6480464 Dinitrochlorobenzene affects the expression of SERPINE1 mRNA CTD PMID:33774146 SERPINE1 Human 1-naphthyl isothiocyanate increases response to substance ISO Serpine1 (Mus musculus) 6480464 SERPINE1 gene mutant form results in increased susceptibility to 1-Naphthylisothiocyanate CTD PMID:24633426 SERPINE1 Human 1-naphthyl isothiocyanate multiple interactions EXP 6480464 [1-Naphthylisothiocyanate co-treated with Cholic Acids] affects the expression of SERPINE1 mRNA CTD PMID:27344345 SERPINE1 Human 1-naphthyl isothiocyanate increases expression ISO Serpine1 (Rattus norvegicus) 6480464 1-Naphthylisothiocyanate results in increased expression of SERPINE1 mRNA CTD PMID:23558518 and PMID:30723492 SERPINE1 Human 1-nitropyrene increases expression EXP 6480464 1-nitropyrene results in increased expression of SERPINE1 mRNA CTD PMID:19041380 SERPINE1 Human 15-deoxy-Delta(12,14)-prostaglandin J2 multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 15-deoxy-delta(12 more ... CTD PMID:18278065 SERPINE1 Human 17alpha-ethynylestradiol multiple interactions EXP 6480464 [Ethinyl Estradiol binds to Norethindrone] which results in decreased expression of SERPINE1 protein more ... CTD PMID:14561536 more ... SERPINE1 Human 17beta-estradiol multiple interactions EXP 6480464 [Estradiol co-treated with Norethindrone Acetate] results in decreased expression of SERPINE1 protein more ... CTD PMID:17393018 more ... SERPINE1 Human 17beta-estradiol affects expression ISO Serpine1 (Rattus norvegicus) 6480464 Estradiol affects the expression of SERPINE1 mRNA CTD PMID:32145629 SERPINE1 Human 17beta-estradiol increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Estradiol results in increased expression of SERPINE1 mRNA CTD PMID:20838740 SERPINE1 Human 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of SERPINE1 mRNA CTD PMID:19619570 more ... SERPINE1 Human 17beta-hydroxy-17-methylestra-4,9,11-trien-3-one increases secretion EXP 6480464 Metribolone results in increased secretion of SERPINE1 protein CTD PMID:20711410 SERPINE1 Human 17beta-hydroxy-5alpha-androstan-3-one multiple interactions EXP 6480464 bicalutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA]] more ... CTD PMID:16317058 SERPINE1 Human 2,2',4,4'-Tetrabromodiphenyl ether decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 2 more ... CTD PMID:20566336 SERPINE1 Human 2,2',4,4'-Tetrabromodiphenyl ether increases expression EXP 6480464 2 more ... CTD PMID:31173147 SERPINE1 Human 2,2,2-tetramine multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Trientine inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA] CTD PMID:16973718 SERPINE1 Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions EXP 6480464 [Estradiol co-treated with Tetrachlorodibenzodioxin] results in decreased expression of SERPINE1 mRNA and Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNA] CTD PMID:11007951 and PMID:19619570 SERPINE1 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Serpine1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of SERPINE1 mRNA CTD PMID:32109520 and PMID:34747641 SERPINE1 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression EXP 6480464 Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNA CTD PMID:11007951 more ... SERPINE1 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Serpine1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of SERPINE1 mRNA CTD PMID:21570461 and PMID:26377647 SERPINE1 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Serpine1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNA and Tetrachlorodibenzodioxin results in increased expression of SERPINE1 protein CTD PMID:12111005 more ... SERPINE1 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of SERPINE1 mRNA CTD PMID:22298810 and PMID:22574217 SERPINE1 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNA and Tetrachlorodibenzodioxin results in increased expression of SERPINE1 protein CTD PMID:12128104 more ... SERPINE1 Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 CGA protein inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 protein] CTD PMID:12128104 SERPINE1 Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin binds to AHR protein] which results in increased expression of SERPINE1 mRNA more ... CTD PMID:12111005 more ... SERPINE1 Human 2,4-diaminotoluene increases expression ISO Serpine1 (Mus musculus) 6480464 2 and 4-diaminotoluene results in increased expression of SERPINE1 mRNA CTD PMID:22016648 SERPINE1 Human 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Serpine1 (Mus musculus) 6480464 2 more ... CTD PMID:38648751 SERPINE1 Human 2,4-dichlorophenol affects binding EXP 6480464 2 and 4-dichlorophenol binds to SERPINE1 protein CTD PMID:32278787 SERPINE1 Human 2,5-dichlorophenol increases expression EXP 6480464 2 and 5-dichlorophenol results in increased expression of SERPINE1 mRNA CTD PMID:38568856 SERPINE1 Human 2,6-di-tert-butyl-4-methylphenol multiple interactions EXP 6480464 Butylated Hydroxytoluene inhibits the reaction [LPA protein results in decreased expression of SERPINE1 protein] and Butylated Hydroxytoluene inhibits the reaction [LPA protein results in increased expression of SERPINE1 protein] CTD PMID:10856522 SERPINE1 Human 2-amino-2-deoxy-D-galactopyranose increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Galactosamine results in increased expression of SERPINE1 mRNA CTD PMID:11779202 SERPINE1 Human 2-butoxyethanol increases expression ISO Serpine1 (Mus musculus) 6480464 n-butoxyethanol results in increased expression of SERPINE1 mRNA CTD PMID:19812364 SERPINE1 Human 2-chloroethanol multiple interactions ISO Serpine1 (Mus musculus) 6480464 Ethylene Chlorohydrin promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA] and Sirolimus inhibits the reaction [Ethylene Chlorohydrin promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA]] CTD PMID:31499194 SERPINE1 Human 2-hydroxypropanoic acid affects expression EXP 6480464 Lactic Acid affects the expression of SERPINE1 mRNA CTD PMID:30851411 SERPINE1 Human 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 pioglitazone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of SERPINE1 mRNA] CTD PMID:16598202 SERPINE1 Human 3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Puromycin Aminonucleoside results in increased expression of SERPINE1 mRNA CTD PMID:16598202 SERPINE1 Human 3,3',4,4',5-pentachlorobiphenyl increases expression ISO Serpine1 (Rattus norvegicus) 6480464 3 more ... CTD PMID:19692669 SERPINE1 Human 3,3',4,4',5-pentachlorobiphenyl increases secretion ISO Serpine1 (Mus musculus) 6480464 3 more ... CTD PMID:29216392 SERPINE1 Human 3,3',4,4',5-pentachlorobiphenyl multiple interactions ISO Serpine1 (Mus musculus) 6480464 3 more ... CTD PMID:28163111 more ... SERPINE1 Human 3,3',4,4',5-pentachlorobiphenyl increases expression ISO Serpine1 (Mus musculus) 6480464 3 more ... CTD PMID:28163111 and PMID:28973532 SERPINE1 Human 3,3',4,4',5-pentachlorobiphenyl affects expression EXP 6480464 3 more ... CTD PMID:21703328 SERPINE1 Human 3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylic acid affects binding EXP 6480464 3-(2 more ... CTD PMID:32278787 SERPINE1 Human 3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 bisindolylmaleimide I inhibits the reaction [AGT protein modified form results in increased expression of SERPINE1 mRNA] more ... CTD PMID:12409145 SERPINE1 Human 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of SERPINE1 mRNA and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SERPINE1 mRNA CTD PMID:16997883 and PMID:28628672 SERPINE1 Human 3-isobutyl-1-methyl-7H-xanthine multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SERPINE1 mRNA and Tetrachlorodibenzodioxin inhibits the reaction [[Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SERPINE1 mRNA] CTD PMID:16054899 SERPINE1 Human 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of SERPINE1 mRNA CTD PMID:16619036 SERPINE1 Human 3-phenylprop-2-enal increases expression EXP 6480464 cinnamaldehyde results in increased expression of SERPINE1 mRNA CTD PMID:19000754 SERPINE1 Human 4'-Methoxychalcone multiple interactions ISO Serpine1 (Mus musculus) 6480464 4'-methoxychalcone analog inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA] CTD PMID:28528971 SERPINE1 Human 4,4'-sulfonyldiphenol decreases expression EXP 6480464 bisphenol S results in decreased expression of SERPINE1 mRNA CTD PMID:27685785 SERPINE1 Human 4,4'-sulfonyldiphenol increases methylation ISO Serpine1 (Mus musculus) 6480464 bisphenol S results in increased methylation of SERPINE1 exon CTD PMID:33297965 SERPINE1 Human 4,4'-sulfonyldiphenol increases expression EXP 6480464 bisphenol S results in increased expression of SERPINE1 mRNA CTD PMID:38568856 SERPINE1 Human 4,4'-sulfonyldiphenol increases expression ISO Serpine1 (Mus musculus) 6480464 bisphenol S results in increased expression of SERPINE1 mRNA CTD PMID:30951980 and PMID:37611474 SERPINE1 Human 4-aminophenol increases expression ISO Serpine1 (Rattus norvegicus) 6480464 4-aminophenol results in increased expression of SERPINE1 mRNA CTD PMID:23558518 SERPINE1 Human 4-hydroxy-TEMPO multiple interactions ISO Serpine1 (Mus musculus) 6480464 tempol inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA] and tempol inhibits the reaction [Hydrogen Peroxide results in increased expression of SERPINE1 mRNA] CTD PMID:17620961 SERPINE1 Human 4-nitrophenol increases expression ISO Serpine1 (Mus musculus) 6480464 4-nitrophenol results in increased expression of SERPINE1 mRNA CTD PMID:34673133 SERPINE1 Human 5-aza-2'-deoxycytidine increases expression EXP 6480464 Decitabine results in increased expression of SERPINE1 mRNA CTD PMID:16367923 SERPINE1 Human 6-propyl-2-thiouracil increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Propylthiouracil results in increased expression of SERPINE1 mRNA CTD PMID:22504374 SERPINE1 Human 8-Br-cAMP multiple interactions EXP 6480464 [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of SERPINE1 mRNA CTD PMID:16997883 SERPINE1 Human 9-cis-retinoic acid multiple interactions EXP 6480464 Alitretinoin inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 protein] CTD PMID:16192631 SERPINE1 Human acetamide increases expression ISO Serpine1 (Rattus norvegicus) 6480464 acetamide results in increased expression of SERPINE1 mRNA CTD PMID:31881176 SERPINE1 Human acrolein increases expression ISO Serpine1 (Mus musculus) 6480464 Acrolein results in increased expression of SERPINE1 mRNA CTD PMID:18515264 SERPINE1 Human acrolein increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Acrolein results in increased expression of SERPINE1 mRNA CTD PMID:38090360 SERPINE1 Human adenine increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Adenine results in increased expression of SERPINE1 mRNA CTD PMID:25766432 SERPINE1 Human adenine multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 camostat inhibits the reaction [Adenine results in increased expression of SERPINE1 mRNA] CTD PMID:25766432 SERPINE1 Human aflatoxin B1 affects expression EXP 6480464 Aflatoxin B1 affects the expression of SERPINE1 protein CTD PMID:20106945 SERPINE1 Human aflatoxin B1 multiple interactions EXP 6480464 [Zearalenone co-treated with Aflatoxin B1] results in increased expression of SERPINE1 mRNA CTD PMID:28965971 SERPINE1 Human aflatoxin B1 increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Aflatoxin B1 results in increased expression of SERPINE1 mRNA CTD PMID:25378103 and PMID:33354967 SERPINE1 Human aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of SERPINE1 mRNA CTD PMID:21632981 more ... SERPINE1 Human aldehydo-D-glucose multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of SERPINE1 mRNA] more ... CTD PMID:11050244 more ... SERPINE1 Human aldehydo-D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of SERPINE1 mRNA CTD PMID:31655124 SERPINE1 Human aldehydo-D-glucose increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Glucose results in increased expression of SERPINE1 mRNA CTD PMID:12409145 SERPINE1 Human aldehydo-D-glucose multiple interactions EXP 6480464 Indomethacin inhibits the reaction [Glucose results in increased secretion of SERPINE1 protein] and SOD2 protein inhibits the reaction [Glucose results in increased expression of SERPINE1 mRNA] CTD PMID:11050244 and PMID:16320596 SERPINE1 Human aldehydo-D-glucose increases secretion EXP 6480464 Glucose results in increased secretion of SERPINE1 protein CTD PMID:16320596 SERPINE1 Human aldosterone multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [Aldosterone co-treated with Glucose] results in increased expression of SERPINE1 mRNA more ... CTD PMID:18682491 and PMID:27773435 SERPINE1 Human aldosterone increases expression EXP 6480464 Aldosterone results in increased expression of SERPINE1 mRNA CTD PMID:30809271 SERPINE1 Human all-trans-retinoic acid multiple interactions ISO Serpine1 (Mus musculus) 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of SERPINE1 mRNA CTD PMID:30951980 SERPINE1 Human Allylamine increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Allylamine results in increased expression of SERPINE1 mRNA CTD PMID:23558518 SERPINE1 Human aminoguanidine multiple interactions EXP 6480464 pimagedine inhibits the reaction [LPA protein modified form results in increased expression of SERPINE1 protein] CTD PMID:10856522 SERPINE1 Human aminoguanidine increases expression ISO Serpine1 (Rattus norvegicus) 6480464 pimagedine results in increased expression of SERPINE1 mRNA CTD PMID:18380797 SERPINE1 Human ammonium chloride affects expression ISO Serpine1 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of SERPINE1 mRNA CTD PMID:16483693 SERPINE1 Human amphibole asbestos decreases expression EXP 6480464 Asbestos and Amphibole results in decreased expression of SERPINE1 protein CTD PMID:20855422 SERPINE1 Human anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [Catechin results in decreased expression of SERPINE1 mRNA] and pyrazolanthrone inhibits the reaction [Quercetin results in decreased expression of SERPINE1 mRNA] CTD PMID:17379280 SERPINE1 Human anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 pyrazolanthrone inhibits the reaction [Valproic Acid results in decreased activity of and results in decreased secretion of SERPINE1 protein] CTD PMID:23378038 SERPINE1 Human antimonite multiple interactions EXP 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of SERPINE1 mRNA CTD PMID:32076005 SERPINE1 Human apocynin multiple interactions EXP 6480464 acetovanillone inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA] CTD PMID:22414048 SERPINE1 Human arecoline increases expression ISO Serpine1 (Mus musculus) 6480464 Arecoline results in increased expression of SERPINE1 protein CTD PMID:26908192 SERPINE1 Human aristolochic acid A decreases expression EXP 6480464 aristolochic acid I results in decreased expression of SERPINE1 mRNA and aristolochic acid I results in decreased expression of SERPINE1 protein CTD PMID:33212167 SERPINE1 Human aristolochic acids increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Aristolochic Acids results in increased expression of SERPINE1 mRNA CTD PMID:19717638 SERPINE1 Human arsane decreases expression EXP 6480464 Arsenic results in decreased expression of SERPINE1 mRNA CTD PMID:11134558 SERPINE1 Human arsane multiple interactions EXP 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of SERPINE1 mRNA CTD PMID:32525701 SERPINE1 Human arsane increases expression EXP 6480464 Arsenic results in increased expression of SERPINE1 mRNA CTD PMID:19945496 SERPINE1 Human arsenic atom decreases expression EXP 6480464 Arsenic results in decreased expression of SERPINE1 mRNA CTD PMID:11134558 SERPINE1 Human arsenic atom multiple interactions EXP 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of SERPINE1 mRNA CTD PMID:32525701 SERPINE1 Human arsenic atom increases expression EXP 6480464 Arsenic results in increased expression of SERPINE1 mRNA CTD PMID:19945496 SERPINE1 Human arsenite(3-) multiple interactions ISO Serpine1 (Mus musculus) 6480464 [arsenite co-treated with Benzo(a)pyrene] results in decreased expression of SERPINE1 mRNA CTD PMID:15894712 SERPINE1 Human arsenite(3-) multiple interactions EXP 6480464 [sodium arsenite results in increased abundance of arsenite] which results in increased expression of SERPINE1 mRNA CTD PMID:32076005 SERPINE1 Human arsenite(3-) increases expression EXP 6480464 arsenite results in increased expression of SERPINE1 mRNA CTD PMID:11864708 and PMID:33451022 SERPINE1 Human arsenite(3-) increases activity EXP 6480464 arsenite results in increased activity of SERPINE1 protein CTD PMID:11864708 SERPINE1 Human arsenite(3-) decreases expression ISO Serpine1 (Mus musculus) 6480464 arsenite results in decreased expression of SERPINE1 mRNA CTD PMID:15894712 SERPINE1 Human arsenite(3-) affects expression ISO Serpine1 (Mus musculus) 6480464 arsenite affects the expression of SERPINE1 mRNA CTD PMID:15738583 SERPINE1 Human arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of SERPINE1 mRNA CTD PMID:26705709 and PMID:31734849 SERPINE1 Human arsenous acid increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Arsenic Trioxide results in increased expression of SERPINE1 mRNA CTD PMID:31734849 SERPINE1 Human arsenous acid multiple interactions EXP 6480464 Arsenic Trioxide inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA] CTD PMID:24762191 SERPINE1 Human arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of SERPINE1 mRNA CTD PMID:17530438 SERPINE1 Human aspalathin multiple interactions EXP 6480464 aspalathin inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein] CTD PMID:25325928 SERPINE1 Human atazanavir sulfate multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SERPINE1 mRNA CTD PMID:32152650 SERPINE1 Human atazanavir sulfate increases expression EXP 6480464 Atazanavir Sulfate results in increased expression of SERPINE1 mRNA CTD PMID:32152650 SERPINE1 Human atorvastatin calcium multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Atorvastatin inhibits the reaction [Fructose results in increased expression of SERPINE1 mRNA] CTD PMID:21122807 SERPINE1 Human atrazine multiple interactions EXP 6480464 [Atrazine co-treated with Arsenates] results in increased expression of SERPINE1 mRNA CTD PMID:18585445 SERPINE1 Human atrazine decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 Atrazine results in decreased expression of SERPINE1 mRNA CTD PMID:36841081 SERPINE1 Human atrazine affects binding EXP 6480464 Atrazine binds to SERPINE1 protein CTD PMID:32278787 SERPINE1 Human atrazine increases expression EXP 6480464 Atrazine results in increased expression of SERPINE1 mRNA CTD PMID:18585445 SERPINE1 Human Aurin increases expression EXP 6480464 aurin results in increased expression of SERPINE1 mRNA CTD PMID:25477506 SERPINE1 Human azathioprine increases expression EXP 6480464 Azathioprine results in increased expression of SERPINE1 mRNA CTD PMID:22623647 SERPINE1 Human barium chloride increases secretion ISO Serpine1 (Rattus norvegicus) 6480464 barium chloride results in increased secretion of SERPINE1 protein CTD PMID:21596853 SERPINE1 Human benazepril decreases expression ISO Serpine1 (Mus musculus) 6480464 benazepril results in decreased expression of SERPINE1 mRNA and benazepril results in decreased expression of SERPINE1 protein CTD PMID:15339989 SERPINE1 Human benazepril multiple interactions ISO Serpine1 (Mus musculus) 6480464 FR 173657 inhibits the reaction [benazepril results in decreased expression of SERPINE1 mRNA] CTD PMID:15339989 SERPINE1 Human benazepril multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 benazepril inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA] CTD PMID:15322501 SERPINE1 Human benzalkonium chloride increases expression ISO Serpine1 (Mus musculus) 6480464 Benzalkonium Compounds results in increased expression of SERPINE1 mRNA CTD PMID:30171875 SERPINE1 Human benzo[a]pyrene decreases expression ISO Serpine1 (Mus musculus) 6480464 Benzo(a)pyrene results in decreased expression of SERPINE1 mRNA CTD PMID:15894712 SERPINE1 Human benzo[a]pyrene affects methylation EXP 6480464 Benzo(a)pyrene affects the methylation of SERPINE1 intron CTD PMID:30157460 SERPINE1 Human benzo[a]pyrene multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with Calcitriol] results in increased expression of SERPINE1 mRNA and [Benzo(a)pyrene co-treated with Calcitriol] results in increased expression of SERPINE1 protein CTD PMID:29524502 SERPINE1 Human benzo[a]pyrene increases methylation EXP 6480464 Benzo(a)pyrene results in increased methylation of SERPINE1 3' UTR CTD PMID:27901495 SERPINE1 Human benzo[a]pyrene decreases methylation EXP 6480464 Benzo(a)pyrene results in decreased methylation of SERPINE1 5' UTR and Benzo(a)pyrene results in decreased methylation of SERPINE1 promoter CTD PMID:27901495 SERPINE1 Human benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of SERPINE1 mRNA CTD PMID:20106945 more ... SERPINE1 Human benzo[a]pyrene increases expression ISO Serpine1 (Mus musculus) 6480464 Benzo(a)pyrene results in increased expression of SERPINE1 mRNA CTD PMID:15034205 more ... SERPINE1 Human benzo[a]pyrene multiple interactions ISO Serpine1 (Mus musculus) 6480464 [arsenite co-treated with Benzo(a)pyrene] results in decreased expression of SERPINE1 mRNA more ... CTD PMID:15034205 more ... SERPINE1 Human benzo[b]fluoranthene increases expression ISO Serpine1 (Mus musculus) 6480464 benzo(b)fluoranthene results in increased expression of SERPINE1 mRNA CTD PMID:26377693 SERPINE1 Human benzo[b]fluoranthene multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of SERPINE1 mRNA CTD PMID:27858113 SERPINE1 Human Benzo[k]fluoranthene increases expression ISO Serpine1 (Mus musculus) 6480464 benzo(k)fluoranthene results in increased expression of SERPINE1 mRNA CTD PMID:26377693 SERPINE1 Human beta-lapachone increases expression EXP 6480464 beta-lapachone results in increased expression of SERPINE1 mRNA CTD PMID:38218311 SERPINE1 Human beta-naphthoflavone increases expression EXP 6480464 beta-Naphthoflavone results in increased expression of SERPINE1 mRNA CTD PMID:19737606 SERPINE1 Human beta-naphthoflavone multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA and isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA] CTD PMID:18164116 more ... SERPINE1 Human beta-naphthoflavone increases expression ISO Serpine1 (Rattus norvegicus) 6480464 beta-Naphthoflavone results in increased expression of SERPINE1 mRNA CTD PMID:22687991 SERPINE1 Human bezafibrate multiple interactions ISO Serpine1 (Mus musculus) 6480464 [CLOCK protein binds to BMAL1 protein] promotes the reaction [Bezafibrate results in increased expression of SERPINE1 mRNA] more ... CTD PMID:20400680 and PMID:20854792 SERPINE1 Human bezafibrate increases expression ISO Serpine1 (Mus musculus) 6480464 Bezafibrate results in increased expression of SERPINE1 mRNA CTD PMID:17118139 more ... SERPINE1 Human bezafibrate increases secretion EXP 6480464 Bezafibrate results in increased secretion of SERPINE1 protein CTD PMID:10364093 SERPINE1 Human bezafibrate increases activity EXP 6480464 Bezafibrate results in increased activity of SERPINE1 protein CTD PMID:9678787 SERPINE1 Human bezafibrate increases expression EXP 6480464 Bezafibrate results in increased expression of SERPINE1 mRNA CTD PMID:10364093 SERPINE1 Human bezafibrate multiple interactions EXP 6480464 Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA] and Bezafibrate inhibits the reaction [[Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 protein] CTD PMID:11292061 SERPINE1 Human bicalutamide multiple interactions EXP 6480464 bicalutamide inhibits the reaction [Dihydrotestosterone inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA]] CTD PMID:16317058 SERPINE1 Human bilirubin IXalpha increases expression EXP 6480464 Bilirubin results in increased expression of SERPINE1 mRNA CTD PMID:20196124 SERPINE1 Human bis(2-ethylhexyl) phthalate increases expression EXP 6480464 Diethylhexyl Phthalate results in increased expression of SERPINE1 mRNA CTD PMID:31163220 SERPINE1 Human bis(2-ethylhexyl) phthalate multiple interactions ISO Serpine1 (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of SERPINE1 mRNA] CTD PMID:33316053 SERPINE1 Human bisphenol A increases expression ISO Serpine1 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of SERPINE1 mRNA CTD PMID:25181051 and PMID:32145629 SERPINE1 Human bisphenol A decreases expression ISO Serpine1 (Mus musculus) 6480464 bisphenol A results in decreased expression of SERPINE1 mRNA CTD PMID:33221593 and PMID:37105096 SERPINE1 Human bisphenol A increases secretion EXP 6480464 bisphenol A results in increased secretion of SERPINE1 protein CTD PMID:31230753 SERPINE1 Human bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of SERPINE1 mRNA CTD PMID:31230753 SERPINE1 Human bisphenol A increases expression ISO Serpine1 (Mus musculus) 6480464 bisphenol A results in increased expression of SERPINE1 mRNA CTD PMID:30951980 SERPINE1 Human bisphenol A decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of SERPINE1 mRNA CTD PMID:30816183 SERPINE1 Human bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of SERPINE1 mRNA CTD PMID:30903817 SERPINE1 Human bisphenol A multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [bisphenol A results in increased secretion of SERPINE1 protein] CTD PMID:31230753 SERPINE1 Human bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of SERPINE1 mRNA and bisphenol A results in decreased expression of SERPINE1 protein CTD PMID:27685785 more ... SERPINE1 Human Bisphenol A diglycidyl ether multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 2 more ... CTD PMID:18278065 SERPINE1 Human Bisphenol B increases expression EXP 6480464 bisphenol B results in increased expression of SERPINE1 protein CTD PMID:34186270 SERPINE1 Human bisphenol F multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SERPINE1 mRNA CTD PMID:28628672 SERPINE1 Human bisphenol F increases expression ISO Serpine1 (Mus musculus) 6480464 bisphenol F results in increased expression of SERPINE1 mRNA CTD PMID:30951980 and PMID:38685157 SERPINE1 Human bisphenol F multiple interactions ISO Serpine1 (Mus musculus) 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of SERPINE1 mRNA CTD PMID:30951980 SERPINE1 Human bleomycin A2 increases expression ISO Serpine1 (Mus musculus) 6480464 Bleomycin results in increased expression of SERPINE1 mRNA and Bleomycin results in increased expression of SERPINE1 protein CTD PMID:29175452 and PMID:35716765 SERPINE1 Human bleomycin A2 multiple interactions ISO Serpine1 (Mus musculus) 6480464 Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SERPINE1 protein] more ... CTD PMID:30825431 and PMID:35716765 SERPINE1 Human bleomycin A2 decreases expression ISO Serpine1 (Mus musculus) 6480464 Bleomycin results in decreased expression of SERPINE1 protein CTD PMID:30825431 SERPINE1 Human bortezomib increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Bortezomib results in increased expression of SERPINE1 mRNA CTD PMID:20830808 SERPINE1 Human busulfan increases expression EXP 6480464 Busulfan results in increased expression of SERPINE1 mRNA and Busulfan results in increased expression of SERPINE1 protein CTD PMID:22286157 SERPINE1 Human busulfan multiple interactions EXP 6480464 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide inhibits the reaction [Busulfan results in increased expression of SERPINE1 mRNA] CTD PMID:22286157 SERPINE1 Human butan-1-ol multiple interactions EXP 6480464 [[Gasoline co-treated with 1-Butanol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of SERPINE1 mRNA CTD PMID:29432896 SERPINE1 Human butanal increases expression EXP 6480464 butyraldehyde results in increased expression of SERPINE1 mRNA CTD PMID:26079696 SERPINE1 Human Butylbenzyl phthalate multiple interactions ISO Serpine1 (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of SERPINE1 mRNA] CTD PMID:33316053 SERPINE1 Human butyric acid increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Butyric Acid results in increased expression of SERPINE1 mRNA CTD PMID:12800193 SERPINE1 Human butyric acid decreases activity ISO Serpine1 (Rattus norvegicus) 6480464 Butyric Acid results in decreased activity of SERPINE1 protein CTD PMID:23378038 SERPINE1 Human C.I. Natural Red 20 multiple interactions ISO Serpine1 (Mus musculus) 6480464 shikonin inhibits the reaction [Antigen-Antibody Complex results in increased expression of SERPINE1 mRNA] CTD PMID:25451590 SERPINE1 Human cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of SERPINE1 mRNA CTD PMID:21172416 and PMID:33952801 SERPINE1 Human cadmium atom multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SERPINE1 mRNA CTD PMID:37325564 SERPINE1 Human cadmium atom increases secretion EXP 6480464 Cadmium results in increased secretion of SERPINE1 protein CTD PMID:33952801 SERPINE1 Human cadmium atom multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SERPINE1 mRNA CTD PMID:29741670 SERPINE1 Human cadmium atom increases expression ISO Serpine1 (Mus musculus) 6480464 Cadmium results in increased expression of SERPINE1 mRNA CTD PMID:22666406 SERPINE1 Human cadmium atom decreases expression EXP 6480464 Cadmium results in decreased expression of SERPINE1 mRNA CTD PMID:22562489 SERPINE1 Human cadmium dichloride multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of SERPINE1 mRNA more ... CTD PMID:23921151 and PMID:37325564 SERPINE1 Human cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of SERPINE1 mRNA CTD PMID:38568856 SERPINE1 Human cadmium dichloride multiple interactions EXP 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in decreased expression of SERPINE1 mRNA CTD PMID:29741670 SERPINE1 Human cadmium selenide multiple interactions EXP 6480464 [cadmium selenide co-treated with zinc sulfide] results in decreased expression of SERPINE1 mRNA CTD PMID:22342292 SERPINE1 Human calciol increases expression ISO Serpine1 (Mus musculus) 6480464 Cholecalciferol results in increased expression of SERPINE1 mRNA CTD PMID:17170073 SERPINE1 Human calcitriol multiple interactions EXP 6480464 [Benzo(a)pyrene co-treated with Calcitriol] results in increased expression of SERPINE1 mRNA and [Benzo(a)pyrene co-treated with Calcitriol] results in increased expression of SERPINE1 protein CTD PMID:29524502 SERPINE1 Human calcium atom increases stability EXP 6480464 Calcium results in increased stability of SERPINE1 protein CTD PMID:21280127 and PMID:21280128 SERPINE1 Human calcium(0) increases stability EXP 6480464 Calcium results in increased stability of SERPINE1 protein CTD PMID:21280127 and PMID:21280128 SERPINE1 Human camostat multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 camostat inhibits the reaction [Adenine results in increased expression of SERPINE1 mRNA] CTD PMID:25766432 SERPINE1 Human cannabidiol decreases expression EXP 6480464 Cannabidiol results in decreased expression of SERPINE1 mRNA CTD PMID:20668920 SERPINE1 Human cannabidiol increases expression ISO Serpine1 (Mus musculus) 6480464 Cannabidiol analog results in increased expression of SERPINE1 protein CTD PMID:30382123 SERPINE1 Human cannabidiol multiple interactions ISO Serpine1 (Mus musculus) 6480464 Cannabidiol analog inhibits the reaction [Bleomycin results in decreased expression of SERPINE1 protein] and Cannabidiol analog promotes the reaction [Dietary Fats results in increased expression of SERPINE1 protein] CTD PMID:30382123 and PMID:30825431 SERPINE1 Human cannabidiol increases response to substance EXP 6480464 SERPINE1 protein results in increased susceptibility to Cannabidiol CTD PMID:20668920 SERPINE1 Human cannabidiol decreases secretion EXP 6480464 Cannabidiol results in decreased secretion of SERPINE1 protein CTD PMID:20668920 SERPINE1 Human cannabidiol multiple interactions EXP 6480464 Cannabidiol inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA] more ... CTD PMID:20668920 and PMID:31250491 SERPINE1 Human cantharidin decreases expression ISO Serpine1 (Mus musculus) 6480464 Cantharidin results in decreased expression of SERPINE1 mRNA CTD PMID:36907384 SERPINE1 Human capsaicin decreases expression EXP 6480464 Capsaicin results in decreased expression of SERPINE1 mRNA CTD PMID:21310942 SERPINE1 Human captan multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SERPINE1 mRNA CTD PMID:32745781 SERPINE1 Human carbamazepine affects expression EXP 6480464 Carbamazepine affects the expression of SERPINE1 mRNA CTD PMID:24752500 and PMID:25979313 SERPINE1 Human carbofuran increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Carbofuran results in increased expression of SERPINE1 mRNA CTD PMID:20211217 SERPINE1 Human carbon nanotube affects expression EXP 6480464 Nanotubes and Carbon affects the expression of SERPINE1 mRNA CTD PMID:25790727 SERPINE1 Human carbon nanotube increases expression ISO Serpine1 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:25620056 SERPINE1 Human carbon nanotube affects expression ISO Serpine1 (Mus musculus) 6480464 Nanotubes and Carbon affects the expression of SERPINE1 mRNA CTD PMID:25620056 SERPINE1 Human carbon nanotube increases expression EXP 6480464 Nanotubes and Carbon results in increased expression of SERPINE1 protein CTD PMID:25790727 SERPINE1 Human carbon nanotube multiple interactions EXP 6480464 [Nanotubes more ... CTD PMID:25790727 SERPINE1 Human carbonyl cyanide p-trifluoromethoxyphenylhydrazone decreases expression EXP 6480464 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of SERPINE1 mRNA CTD PMID:16039398 SERPINE1 Human chenodeoxycholic acid multiple interactions ISO Serpine1 (Mus musculus) 6480464 EGR1 promotes the reaction [Chenodeoxycholic Acid results in increased expression of SERPINE1 mRNA] CTD PMID:21224055 SERPINE1 Human chenodeoxycholic acid multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SERPINE1 mRNA more ... CTD PMID:32152650 and PMID:33819548 SERPINE1 Human chenodeoxycholic acid increases expression ISO Serpine1 (Mus musculus) 6480464 Chenodeoxycholic Acid results in increased expression of SERPINE1 mRNA CTD PMID:21224055 SERPINE1 Human chloroform increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Chloroform results in increased expression of SERPINE1 mRNA CTD PMID:23558518 SERPINE1 Human chloropicrin affects expression EXP 6480464 chloropicrin affects the expression of SERPINE1 mRNA CTD PMID:26352163 SERPINE1 Human chloropicrin decreases expression EXP 6480464 chloropicrin results in decreased expression of SERPINE1 mRNA CTD PMID:28476498 SERPINE1 Human chloroquine multiple interactions EXP 6480464 Chloroquine inhibits the reaction [Poly I-C results in increased expression of SERPINE1 mRNA] and Chloroquine inhibits the reaction [Poly I-C results in increased expression of SERPINE1 protein] CTD PMID:30341573 SERPINE1 Human chlorpyrifos multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SERPINE1 mRNA CTD PMID:32745781 SERPINE1 Human chlorpyrifos increases expression ISO Serpine1 (Mus musculus) 6480464 Chlorpyrifos results in increased expression of SERPINE1 mRNA CTD PMID:37019170 SERPINE1 Human choline multiple interactions ISO Serpine1 (Mus musculus) 6480464 3 more ... CTD PMID:19593819 more ... SERPINE1 Human choline increases methylation EXP 6480464 Choline results in increased methylation of SERPINE1 gene CTD PMID:30116142 SERPINE1 Human choline multiple interactions EXP 6480464 [Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SERPINE1 mRNA and [Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased methylation of SERPINE1 gene CTD PMID:30116142 SERPINE1 Human chromium(6+) multiple interactions EXP 6480464 [zinc chromate results in increased abundance of chromium hexavalent ion] which results in decreased expression of SERPINE1 mRNA CTD PMID:38479592 SERPINE1 Human chrysene multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of SERPINE1 mRNA CTD PMID:27858113 SERPINE1 Human ciglitazone multiple interactions EXP 6480464 [ciglitazone binds to PPARG protein alternative form] which results in increased expression of SERPINE1 mRNA and [ciglitazone binds to PPARG protein] which results in increased expression of SERPINE1 mRNA CTD PMID:16197558 SERPINE1 Human cis-caffeic acid multiple interactions ISO Serpine1 (Mus musculus) 6480464 caffeic acid inhibits the reaction [Acetaminophen results in increased expression of SERPINE1 protein] CTD PMID:27720869 SERPINE1 Human cisplatin decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 Cisplatin results in decreased expression of SERPINE1 mRNA CTD PMID:22023808 SERPINE1 Human cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with jinfukang] results in decreased expression of SERPINE1 mRNA CTD PMID:27392435 SERPINE1 Human cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of SERPINE1 mRNA CTD PMID:21532991 SERPINE1 Human cisplatin affects expression ISO Serpine1 (Mus musculus) 6480464 Cisplatin affects the expression of SERPINE1 mRNA CTD PMID:21151649 SERPINE1 Human clofibrate increases expression ISO Serpine1 (Mus musculus) 6480464 Clofibrate results in increased expression of SERPINE1 mRNA CTD PMID:23811191 SERPINE1 Human clofibric acid increases expression EXP 6480464 Clofibric Acid results in increased expression of SERPINE1 mRNA CTD PMID:10364093 SERPINE1 Human clofibric acid increases secretion EXP 6480464 Clofibric Acid results in increased secretion of SERPINE1 protein CTD PMID:10364093 SERPINE1 Human Clofop multiple interactions EXP 6480464 [fenofibric acid binds to PPARA protein] which results in increased expression of SERPINE1 mRNA CTD PMID:16197558 SERPINE1 Human Clofop decreases secretion EXP 6480464 fenofibric acid results in decreased secretion of SERPINE1 protein CTD PMID:10364093 SERPINE1 Human Clofop decreases expression EXP 6480464 fenofibric acid results in decreased expression of SERPINE1 mRNA CTD PMID:10364093 SERPINE1 Human clothianidin decreases expression EXP 6480464 clothianidin results in decreased expression of SERPINE1 mRNA CTD PMID:31626844 SERPINE1 Human cobalt atom decreases stability EXP 6480464 Cobalt results in decreased stability of SERPINE1 protein CTD PMID:21280127 and PMID:21280128 SERPINE1 Human cobalt atom multiple interactions EXP 6480464 VTN protein inhibits the reaction [Cobalt results in decreased stability of SERPINE1 protein] CTD PMID:21280127 and PMID:21280128 SERPINE1 Human cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of SERPINE1 mRNA CTD PMID:18344023 more ... SERPINE1 Human cobalt dichloride multiple interactions EXP 6480464 sauchinone inhibits the reaction [cobaltous chloride results in increased expression of SERPINE1 mRNA] CTD PMID:27871897 SERPINE1 Human copper atom multiple interactions EXP 6480464 [Chelating Agents binds to Copper] which results in increased expression of SERPINE1 mRNA more ... CTD PMID:11681624 more ... SERPINE1 Human copper atom decreases stability EXP 6480464 Copper results in decreased stability of SERPINE1 protein CTD PMID:21280127 SERPINE1 Human copper(0) multiple interactions EXP 6480464 [Chelating Agents binds to Copper] which results in increased expression of SERPINE1 mRNA more ... CTD PMID:11681624 more ... SERPINE1 Human copper(0) decreases stability EXP 6480464 Copper results in decreased stability of SERPINE1 protein CTD PMID:21280127 SERPINE1 Human copper(II) chloride increases expression EXP 6480464 cupric chloride results in increased expression of SERPINE1 mRNA CTD PMID:38568856 SERPINE1 Human copper(II) sulfate increases expression EXP 6480464 Copper Sulfate results in increased expression of SERPINE1 mRNA CTD PMID:16283523 SERPINE1 Human corosolic acid increases expression EXP 6480464 corosolic acid results in increased expression of SERPINE1 mRNA CTD PMID:37939859 SERPINE1 Human crocidolite asbestos decreases expression ISO Serpine1 (Mus musculus) 6480464 Asbestos and Crocidolite results in decreased expression of SERPINE1 mRNA CTD PMID:23917077 SERPINE1 Human crocidolite asbestos increases expression EXP 6480464 Asbestos more ... CTD PMID:17975199 more ... SERPINE1 Human CU-O LINKAGE increases expression ISO Serpine1 (Mus musculus) 6480464 cupric oxide results in increased expression of SERPINE1 mRNA and cupric oxide results in increased expression of SERPINE1 protein CTD PMID:20171267 SERPINE1 Human CU-O LINKAGE multiple interactions ISO Serpine1 (Mus musculus) 6480464 SB 203580 inhibits the reaction [cupric oxide results in increased expression of SERPINE1 mRNA] CTD PMID:20171267 SERPINE1 Human curcumin increases expression EXP 6480464 Curcumin results in increased expression of SERPINE1 mRNA CTD PMID:15713895 SERPINE1 Human curcumin multiple interactions ISO Serpine1 (Mus musculus) 6480464 Curcumin inhibits the reaction [Bleomycin results in increased expression of SERPINE1 mRNA] and Curcumin inhibits the reaction [Bleomycin results in increased expression of SERPINE1 protein] CTD PMID:35716765 SERPINE1 Human cyanocob(III)alamin increases methylation EXP 6480464 Vitamin B 12 results in increased methylation of SERPINE1 gene CTD PMID:30116142 SERPINE1 Human cyanocob(III)alamin multiple interactions EXP 6480464 [Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SERPINE1 mRNA and [Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased methylation of SERPINE1 gene CTD PMID:30116142 SERPINE1 Human cycloheximide multiple interactions ISO Serpine1 (Mus musculus) 6480464 Cycloheximide promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNA] CTD PMID:12111005 SERPINE1 Human cycloheximide multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Cycloheximide inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA] and Cycloheximide promotes the reaction [FGF2 protein results in increased expression of SERPINE1 mRNA] CTD PMID:9798919 SERPINE1 Human cycloheximide multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [Tetrachlorodibenzodioxin results in increased expression of SERPINE1 mRNA] CTD PMID:11007951 SERPINE1 Human cyclophosphamide increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Cyclophosphamide results in increased expression of SERPINE1 mRNA CTD PMID:23558518 SERPINE1 Human cyclosporin A decreases expression ISO Serpine1 (Mus musculus) 6480464 Cyclosporine results in decreased expression of SERPINE1 mRNA CTD PMID:19770486 SERPINE1 Human cyclosporin A multiple interactions EXP 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SERPINE1 mRNA CTD PMID:32152650 SERPINE1 Human cyclosporin A multiple interactions ISO Serpine1 (Mus musculus) 6480464 ethyl 6-(N-(2-chloro-4-fluorophenyl)sulfamoyl)cyclohex-1-ene-1-carboxylate inhibits the reaction [Cyclosporine results in increased expression of SERPINE1 mRNA] and TLR4 gene mutant form inhibits the reaction [Cyclosporine results in increased expression of SERPINE1 mRNA] CTD PMID:27585667 SERPINE1 Human cyclosporin A increases expression ISO Serpine1 (Mus musculus) 6480464 Cyclosporine results in increased expression of SERPINE1 mRNA CTD PMID:27585667 SERPINE1 Human cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of SERPINE1 mRNA CTD PMID:20106945 more ... SERPINE1 Human cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of SERPINE1 mRNA CTD PMID:22147139 SERPINE1 Human cyclosporin A increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Cyclosporine results in increased expression of SERPINE1 mRNA CTD PMID:21865292 and PMID:27585667 SERPINE1 Human D-glucose increases secretion EXP 6480464 Glucose results in increased secretion of SERPINE1 protein CTD PMID:16320596 SERPINE1 Human D-glucose decreases expression EXP 6480464 Glucose results in decreased expression of SERPINE1 mRNA CTD PMID:31655124 SERPINE1 Human D-glucose increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Glucose results in increased expression of SERPINE1 mRNA CTD PMID:12409145 SERPINE1 Human D-glucose multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of SERPINE1 mRNA] more ... CTD PMID:11050244 more ... SERPINE1 Human D-glucose multiple interactions EXP 6480464 Indomethacin inhibits the reaction [Glucose results in increased secretion of SERPINE1 protein] and SOD2 protein inhibits the reaction [Glucose results in increased expression of SERPINE1 mRNA] CTD PMID:11050244 and PMID:16320596 SERPINE1 Human daunorubicin decreases expression EXP 6480464 Daunorubicin results in decreased expression of SERPINE1 mRNA and Daunorubicin results in decreased expression of SERPINE1 protein CTD PMID:11336794 SERPINE1 Human daunorubicin decreases secretion ISO Serpine1 (Rattus norvegicus) 6480464 Daunorubicin results in decreased secretion of SERPINE1 protein CTD PMID:11107162 SERPINE1 Human daunorubicin multiple interactions EXP 6480464 [Daunorubicin results in increased abundance of Ceramides] which results in decreased secretion of SERPINE1 protein and fumonisin B1 inhibits the reaction [Daunorubicin results in decreased expression of SERPINE1 protein] CTD PMID:11107162 and PMID:11336794 SERPINE1 Human decabromodiphenyl ether increases expression ISO Serpine1 (Rattus norvegicus) 6480464 decabromobiphenyl ether results in increased expression of SERPINE1 mRNA CTD PMID:23914054 SERPINE1 Human deoxycholic acid multiple interactions ISO Serpine1 (Mus musculus) 6480464 EGR1 promotes the reaction [Deoxycholic Acid results in increased expression of SERPINE1 mRNA] CTD PMID:21224055 SERPINE1 Human deoxycholic acid multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SERPINE1 mRNA more ... CTD PMID:32152650 and PMID:33819548 SERPINE1 Human deoxycholic acid increases expression ISO Serpine1 (Mus musculus) 6480464 Deoxycholic Acid results in increased expression of SERPINE1 mRNA CTD PMID:21224055 SERPINE1 Human dexamethasone multiple interactions EXP 6480464 [Dexamethasone co-treated with 8-Bromo Cyclic Adenosine Monophosphate co-treated with 1-Methyl-3-isobutylxanthine] results in decreased expression of SERPINE1 mRNA more ... CTD PMID:16997883 more ... SERPINE1 Human dexamethasone increases secretion EXP 6480464 Dexamethasone results in increased secretion of SERPINE1 protein CTD PMID:21524281 SERPINE1 Human dexamethasone increases expression EXP 6480464 Dexamethasone results in increased expression of SERPINE1 mRNA CTD PMID:21524281 SERPINE1 Human dexamethasone increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Dexamethasone results in increased expression of SERPINE1 protein CTD PMID:3127913 SERPINE1 Human dexamethasone multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Dexamethasone promotes the reaction [IL1B protein results in increased expression of SERPINE1 protein] CTD PMID:15963473 SERPINE1 Human dexamethasone multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Dexamethasone co-treated with rosiglitazone co-treated with 1-Methyl-3-isobutylxanthine co-treated with INS1 protein] results in increased expression of SERPINE1 mRNA more ... CTD PMID:16054899 and PMID:21731756 SERPINE1 Human dextran sulfate multiple interactions ISO Serpine1 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SERPINE1 mRNA CTD PMID:29950665 SERPINE1 Human diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of SERPINE1 mRNA CTD PMID:26705709 and PMID:31734849 SERPINE1 Human diarsenic trioxide increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Arsenic Trioxide results in increased expression of SERPINE1 mRNA CTD PMID:31734849 SERPINE1 Human diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of SERPINE1 mRNA CTD PMID:17530438 SERPINE1 Human diarsenic trioxide multiple interactions EXP 6480464 Arsenic Trioxide inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA] CTD PMID:24762191 SERPINE1 Human dibenz[a,h]anthracene increases expression ISO Serpine1 (Mus musculus) 6480464 1 more ... CTD PMID:26377693 SERPINE1 Human dibenzofuran increases expression ISO Serpine1 (Rattus norvegicus) 6480464 dibenzofuran analog results in increased expression of SERPINE1 mRNA CTD PMID:20566336 SERPINE1 Human dibutyl phthalate increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Dibutyl Phthalate results in increased expression of SERPINE1 mRNA CTD PMID:21266533 SERPINE1 Human dibutyl phthalate multiple interactions ISO Serpine1 (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of SERPINE1 mRNA] CTD PMID:33316053 SERPINE1 Human dibutyl phthalate increases expression ISO Serpine1 (Mus musculus) 6480464 Dibutyl Phthalate results in increased expression of SERPINE1 mRNA CTD PMID:21266533 SERPINE1 Human dichlorine increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Chlorine results in increased expression of SERPINE1 mRNA CTD PMID:18636392 SERPINE1 Human dichlorine multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [Ozone co-treated with Chlorine] affects the expression of SERPINE1 mRNA CTD PMID:18636392 SERPINE1 Human dichloroacetic acid increases expression ISO Serpine1 (Mus musculus) 6480464 Dichloroacetic Acid results in increased expression of SERPINE1 mRNA CTD PMID:28962523 SERPINE1 Human diclofenac multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Diclofenac promotes the reaction [lipopolysaccharide and E coli O55-B5 results in increased expression of SERPINE1 mRNA] CTD PMID:23939143 SERPINE1 Human diclofenac increases expression ISO Serpine1 (Mus musculus) 6480464 Diclofenac results in increased expression of SERPINE1 mRNA CTD PMID:26934552 and PMID:35537566 SERPINE1 Human diclofenac affects expression EXP 6480464 Diclofenac affects the expression of SERPINE1 mRNA CTD PMID:24752500 SERPINE1 Human dicrotophos increases expression EXP 6480464 dicrotophos results in increased expression of SERPINE1 mRNA CTD PMID:28302478 SERPINE1 Human Didecyldimethylammonium decreases expression EXP 6480464 didecyldimethylammonium results in decreased expression of SERPINE1 mRNA CTD PMID:32763356 SERPINE1 Human dieldrin increases expression EXP 6480464 Dieldrin results in increased expression of SERPINE1 mRNA CTD PMID:31068361 SERPINE1 Human dienogest multiple interactions EXP 6480464 [Ethinyl Estradiol co-treated with dienogest] results in decreased expression of SERPINE1 protein CTD PMID:15288212 SERPINE1 Human diethyl phthalate multiple interactions ISO Serpine1 (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of SERPINE1 mRNA] CTD PMID:33316053 SERPINE1 Human diisobutyl phthalate multiple interactions ISO Serpine1 (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of SERPINE1 mRNA] CTD PMID:33316053 SERPINE1 Human diisononyl phthalate multiple interactions ISO Serpine1 (Mus musculus) 6480464 [diethyl phthalate co-treated with Diethylhexyl Phthalate co-treated with Dibutyl Phthalate co-treated with diisononyl phthalate co-treated with diisobutyl phthalate co-treated with butylbenzyl phthalate] inhibits the reaction [CGA protein results in increased expression of SERPINE1 mRNA] CTD PMID:33316053 SERPINE1 Human dinitrogen multiple interactions EXP 6480464 [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of SERPINE1 protein CTD PMID:30711708 SERPINE1 Human dioxygen multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 4-amino-5-(4-methylphenyl)-7-(tert-butyl)pyrazolo(3 more ... CTD PMID:15913578 and PMID:33729688 SERPINE1 Human dioxygen multiple interactions ISO Serpine1 (Mus musculus) 6480464 [NFE2L2 protein affects the susceptibility to Oxygen] which affects the expression of SERPINE1 mRNA more ... CTD PMID:30096613 and PMID:30529165 SERPINE1 Human dioxygen increases expression EXP 6480464 Oxygen deficiency results in increased expression of SERPINE1 mRNA and Oxygen deficiency results in increased expression of SERPINE1 protein CTD PMID:12719791 more ... SERPINE1 Human dioxygen multiple interactions EXP 6480464 APEX1 protein inhibits the reaction [RAC1 protein inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]] more ... CTD PMID:12719791 more ... SERPINE1 Human dioxygen increases expression ISO Serpine1 (Mus musculus) 6480464 Oxygen deficiency results in increased expression of SERPINE1 mRNA and Oxygen deficiency results in increased expression of SERPINE1 protein CTD PMID:23539316 more ... SERPINE1 Human dioxygen increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Oxygen deficiency results in increased expression of SERPINE1 mRNA CTD PMID:15913578 SERPINE1 Human dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate multiple interactions EXP 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of SERPINE1 mRNA CTD PMID:32076005 SERPINE1 Human diquat increases expression EXP 6480464 Diquat results in increased expression of SERPINE1 mRNA CTD PMID:21172416 SERPINE1 Human dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 SERPINE1 Human doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of SERPINE1 mRNA CTD PMID:16705698 SERPINE1 Human doxorubicin affects expression EXP 6480464 Doxorubicin affects the expression of SERPINE1 mRNA CTD PMID:29803840 SERPINE1 Human doxorubicin increases expression ISO Serpine1 (Mus musculus) 6480464 Doxorubicin results in increased expression of SERPINE1 mRNA CTD PMID:21040762 more ... SERPINE1 Human doxorubicin increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Doxorubicin results in increased expression of SERPINE1 mRNA CTD PMID:20211217 and PMID:23558518 SERPINE1 Human doxorubicin multiple interactions ISO Serpine1 (Mus musculus) 6480464 [[MT1 protein co-treated with MT2 protein] affects the susceptibility to Doxorubicin] which affects the expression of SERPINE1 mRNA and Niclosamide inhibits the reaction [Doxorubicin results in increased expression of SERPINE1 mRNA] CTD PMID:21040762 and PMID:28318631 SERPINE1 Human doxorubicin affects response to substance EXP 6480464 SERPINE1 protein affects the susceptibility to Doxorubicin CTD PMID:16217747 SERPINE1 Human doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of SERPINE1 mRNA CTD PMID:15870702 and PMID:30031762 SERPINE1 Human efavirenz increases secretion EXP 6480464 efavirenz results in increased secretion of SERPINE1 protein CTD PMID:21619898 SERPINE1 Human emodin multiple interactions EXP 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one promotes the reaction [Emodin inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein]] more ... CTD PMID:14534369 SERPINE1 Human enalapril multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [eplerenone co-treated with Enalapril] inhibits the reaction [[Aldosterone co-treated with Glucose] results in increased expression of SERPINE1 mRNA] more ... CTD PMID:18682491 SERPINE1 Human enalapril decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 Enalapril results in decreased expression of SERPINE1 mRNA and Enalapril results in decreased expression of SERPINE1 protein CTD PMID:18682491 SERPINE1 Human enalaprilat dihydrate decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 Enalaprilat results in decreased expression of SERPINE1 mRNA CTD PMID:21795644 SERPINE1 Human endosulfan multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Ascorbic Acid promotes the reaction [Vitamin E inhibits the reaction [Endosulfan results in increased activity of SERPINE1 protein]] and Vitamin E inhibits the reaction [Endosulfan results in increased activity of SERPINE1 protein] CTD PMID:21804306 SERPINE1 Human endosulfan increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Endosulfan results in increased expression of SERPINE1 mRNA CTD PMID:29391264 SERPINE1 Human endosulfan increases activity ISO Serpine1 (Rattus norvegicus) 6480464 Endosulfan results in increased activity of SERPINE1 protein CTD PMID:21804306 SERPINE1 Human entinostat increases expression EXP 6480464 entinostat results in increased expression of SERPINE1 mRNA CTD PMID:26272509 and PMID:27188386 SERPINE1 Human entinostat multiple interactions EXP 6480464 [NOG protein co-treated with entinostat co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SERPINE1 mRNA CTD PMID:27188386 SERPINE1 Human eplerenone multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [eplerenone co-treated with Enalapril] inhibits the reaction [[Aldosterone co-treated with Glucose] results in increased expression of SERPINE1 mRNA] more ... CTD PMID:18682491 SERPINE1 Human eplerenone decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 eplerenone results in decreased expression of SERPINE1 mRNA and eplerenone results in decreased expression of SERPINE1 protein CTD PMID:18682491 SERPINE1 Human eprosartan decreases expression ISO Serpine1 (Rattus norvegicus) 28912746 eprosartan decreases expression of plasminogen activator inhibitor -1 mRNA in high fat high sodium fed SHRSP/A3N rat kidney RGD SERPINE1 Human Ethyl icosapentate decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 eicosapentaenoic acid ethyl ester results in decreased expression of SERPINE1 protein CTD PMID:14614217 SERPINE1 Human ethyl methanesulfonate increases expression EXP 6480464 Ethyl Methanesulfonate results in increased expression of SERPINE1 mRNA CTD PMID:23649840 SERPINE1 Human famotidine multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Heparin promotes the reaction [[Famotidine co-treated with Lipopolysaccharides] results in increased expression of SERPINE1 protein] CTD PMID:16401727 SERPINE1 Human fenofibrate multiple interactions ISO Serpine1 (Mus musculus) 6480464 Fenofibrate inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of SERPINE1 mRNA] more ... CTD PMID:19593819 SERPINE1 Human fenofibrate multiple interactions EXP 6480464 Fenofibrate inhibits the reaction [NR4A1 protein results in increased expression of SERPINE1 mRNA] more ... CTD PMID:19593819 SERPINE1 Human fenofibrate multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [Fenofibrate co-treated with Diethylnitrosamine] results in increased expression of SERPINE1 mRNA CTD PMID:18253720 SERPINE1 Human fenofibrate affects expression ISO Serpine1 (Rattus norvegicus) 6480464 Fenofibrate affects the expression of SERPINE1 mRNA CTD PMID:20801182 SERPINE1 Human fipronil increases expression ISO Serpine1 (Rattus norvegicus) 6480464 fipronil results in increased expression of SERPINE1 mRNA CTD PMID:34044035 SERPINE1 Human flutamide increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Flutamide results in increased expression of SERPINE1 mRNA CTD PMID:24793618 SERPINE1 Human folic acid multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in increased expression of SERPINE1 mRNA CTD PMID:20938992 SERPINE1 Human folic acid increases methylation EXP 6480464 Folic Acid results in increased methylation of SERPINE1 gene CTD PMID:30116142 SERPINE1 Human folic acid increases expression EXP 6480464 Folic Acid results in increased expression of SERPINE1 mRNA CTD PMID:30116142 SERPINE1 Human folic acid multiple interactions EXP 6480464 [Choline co-treated with Vitamin B 12 co-treated with Folic Acid] results in increased expression of SERPINE1 mRNA more ... CTD PMID:30116142 and PMID:31170432 SERPINE1 Human formaldehyde increases expression EXP 6480464 Formaldehyde results in increased expression of SERPINE1 mRNA CTD PMID:23649840 and PMID:27664576 SERPINE1 Human fosinopril multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [Valsartan co-treated with Fosinopril] results in decreased expression of SERPINE1 mRNA and [Valsartan co-treated with Fosinopril] results in decreased expression of SERPINE1 protein CTD PMID:21051829 SERPINE1 Human fosinopril decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 Fosinopril results in decreased expression of SERPINE1 mRNA and Fosinopril results in decreased expression of SERPINE1 protein CTD PMID:21051829 SERPINE1 Human fructose increases secretion ISO Serpine1 (Rattus norvegicus) 6480464 Fructose results in increased secretion of SERPINE1 protein CTD PMID:19165636 SERPINE1 Human fructose increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Fructose results in increased expression of SERPINE1 mRNA and Fructose results in increased expression of SERPINE1 protein CTD PMID:21122807 more ... SERPINE1 Human fructose multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Atorvastatin inhibits the reaction [Fructose results in increased expression of SERPINE1 mRNA] more ... CTD PMID:21122807 more ... SERPINE1 Human fulvestrant multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [bisphenol A results in increased secretion of SERPINE1 protein] CTD PMID:31230753 SERPINE1 Human fumonisin B1 multiple interactions EXP 6480464 fumonisin B1 inhibits the reaction [Daunorubicin results in decreased expression of SERPINE1 protein] CTD PMID:11336794 SERPINE1 Human geldanamycin increases expression EXP 6480464 geldanamycin results in increased expression of SERPINE1 mRNA CTD PMID:26705709 SERPINE1 Human gemfibrozil decreases secretion EXP 6480464 Gemfibrozil results in decreased secretion of SERPINE1 protein CTD PMID:10364093 SERPINE1 Human gemfibrozil decreases expression EXP 6480464 Gemfibrozil results in decreased expression of SERPINE1 mRNA CTD PMID:10364093 SERPINE1 Human gemfibrozil increases activity EXP 6480464 Gemfibrozil results in increased activity of SERPINE1 protein CTD PMID:9678787 SERPINE1 Human genistein multiple interactions EXP 6480464 Genistein inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein] and Genistein promotes the reaction [troglitazone inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein]] CTD PMID:14534369 SERPINE1 Human genistein decreases expression ISO Serpine1 (Mus musculus) 6480464 Genistein results in decreased expression of SERPINE1 mRNA CTD PMID:32186404 SERPINE1 Human genistein increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Genistein results in increased expression of SERPINE1 mRNA CTD PMID:20838740 SERPINE1 Human genistein decreases expression EXP 6480464 Genistein results in decreased expression of SERPINE1 mRNA CTD PMID:22228119 SERPINE1 Human gentamycin multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of SERPINE1 protein and CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of SERPINE1 protein] CTD PMID:23335628 SERPINE1 Human gentamycin increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Gentamicins results in increased expression of SERPINE1 mRNA CTD PMID:33387578 SERPINE1 Human gestodene multiple interactions EXP 6480464 [Ethinyl Estradiol co-treated with Gestodene] results in increased activity of SERPINE1 protein CTD PMID:15504374 SERPINE1 Human Gingerenone A increases expression EXP 6480464 gingerenone A results in increased expression of SERPINE1 mRNA CTD PMID:35326237 SERPINE1 Human glucose increases secretion EXP 6480464 Glucose results in increased secretion of SERPINE1 protein CTD PMID:16320596 SERPINE1 Human glucose increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Glucose results in increased expression of SERPINE1 mRNA CTD PMID:12409145 SERPINE1 Human glucose decreases expression EXP 6480464 Glucose results in decreased expression of SERPINE1 mRNA CTD PMID:31655124 SERPINE1 Human glucose multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of SERPINE1 mRNA] more ... CTD PMID:11050244 more ... SERPINE1 Human glucose multiple interactions EXP 6480464 Indomethacin inhibits the reaction [Glucose results in increased secretion of SERPINE1 protein] and SOD2 protein inhibits the reaction [Glucose results in increased expression of SERPINE1 mRNA] CTD PMID:11050244 and PMID:16320596 SERPINE1 Human glycochenodeoxycholic acid multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SERPINE1 mRNA more ... CTD PMID:32152650 and PMID:33819548 SERPINE1 Human glycocholic acid multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SERPINE1 mRNA more ... CTD PMID:32152650 and PMID:33819548 SERPINE1 Human glycodeoxycholic acid multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SERPINE1 mRNA more ... CTD PMID:32152650 and PMID:33819548 SERPINE1 Human Goe 6976 multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Go 6976 inhibits the reaction [NGF protein results in increased expression of SERPINE1 mRNA] and Go 6976 inhibits the reaction [NGF protein results in increased expression of SERPINE1 protein] CTD PMID:23825664 SERPINE1 Human gold atom increases expression EXP 6480464 Gold results in increased expression of SERPINE1 mRNA CTD PMID:29705079 SERPINE1 Human gold(0) increases expression EXP 6480464 Gold results in increased expression of SERPINE1 mRNA CTD PMID:29705079 SERPINE1 Human graphite increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Graphite results in increased expression of SERPINE1 mRNA CTD PMID:29933104 SERPINE1 Human guanethidine multiple interactions ISO Serpine1 (Mus musculus) 6480464 Guanethidine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA] CTD PMID:15850565 SERPINE1 Human GW 501516 multiple interactions EXP 6480464 [GW 501516 binds to PPARD protein] which results in increased expression of SERPINE1 mRNA CTD PMID:16197558 SERPINE1 Human heparin multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Heparin inhibits the reaction [Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE1 protein]] and Heparin promotes the reaction [[Famotidine co-treated with Lipopolysaccharides] results in increased expression of SERPINE1 protein] CTD PMID:16401727 SERPINE1 Human hexadecanoic acid increases expression EXP 6480464 Palmitic Acid results in increased expression of SERPINE1 mRNA CTD PMID:17658692 SERPINE1 Human hexadecanoic acid multiple interactions EXP 6480464 [Palmitic Acid co-treated with Oleic Acid co-treated with TNF protein] affects the expression of SERPINE1 mRNA CTD PMID:30547786 SERPINE1 Human Hexadimethrine bromide multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Hexadimethrine Bromide inhibits the reaction [2-chloroethyl ethyl sulfide results in increased expression of SERPINE1 mRNA] CTD PMID:32157350 SERPINE1 Human Honokiol affects expression ISO Serpine1 (Rattus norvegicus) 6480464 honokiol affects the expression of SERPINE1 mRNA CTD PMID:21265825 SERPINE1 Human Honokiol multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 honokiol inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 protein] CTD PMID:21265825 SERPINE1 Human hydralazine multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of SERPINE1 mRNA and [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of SERPINE1 protein CTD PMID:11318962 SERPINE1 Human hydralazine decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 Hydralazine results in decreased expression of SERPINE1 mRNA CTD PMID:23415681 SERPINE1 Human hydrochlorothiazide multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of SERPINE1 mRNA and [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of SERPINE1 protein CTD PMID:11318962 SERPINE1 Human hydrogen chloride affects response to substance ISO Serpine1 (Mus musculus) 6480464 SERPINE1 protein affects the susceptibility to Hydrochloric Acid CTD PMID:19060228 SERPINE1 Human hydrogen peroxide increases expression ISO Serpine1 (Mus musculus) 6480464 Hydrogen Peroxide results in increased expression of SERPINE1 mRNA CTD PMID:17620961 SERPINE1 Human hydrogen peroxide increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Hydrogen Peroxide results in increased expression of SERPINE1 mRNA CTD PMID:12409145 SERPINE1 Human hydrogen peroxide multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Hydrogen Peroxide results in increased expression of SERPINE1 mRNA] and bisindolylmaleimide I inhibits the reaction [Hydrogen Peroxide results in increased expression of SERPINE1 mRNA] CTD PMID:12409145 SERPINE1 Human hydrogen peroxide increases expression EXP 6480464 Hydrogen Peroxide results in increased expression of SERPINE1 mRNA and Hydrogen Peroxide results in increased expression of SERPINE1 protein CTD PMID:19401454 and PMID:32949572 SERPINE1 Human hydrogen peroxide multiple interactions ISO Serpine1 (Mus musculus) 6480464 telmisartan inhibits the reaction [Hydrogen Peroxide results in increased expression of SERPINE1 mRNA] and tempol inhibits the reaction [Hydrogen Peroxide results in increased expression of SERPINE1 mRNA] CTD PMID:17620961 SERPINE1 Human hydrogen sulfide increases expression ISO Serpine1 (Mus musculus) 6480464 Hydrogen Sulfide results in increased expression of SERPINE1 mRNA CTD PMID:31843631 SERPINE1 Human hydroxychloroquine multiple interactions EXP 6480464 Hydroxychloroquine inhibits the reaction [Poly I-C results in increased expression of SERPINE1 mRNA] and Hydroxychloroquine inhibits the reaction [Poly I-C results in increased expression of SERPINE1 protein] CTD PMID:30341573 SERPINE1 Human hydroxyl multiple interactions EXP 6480464 [[Superoxides co-treated with Hydroxyl Radical] results in increased oxidation of LPA protein] which results in decreased secretion of SERPINE1 protein CTD PMID:11681624 SERPINE1 Human hypochlorous acid increases expression ISO Serpine1 (Mus musculus) 6480464 Hypochlorous Acid results in increased expression of SERPINE1 mRNA CTD PMID:19376150 SERPINE1 Human indirubin-3'-monoxime multiple interactions EXP 6480464 [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 mRNA CTD PMID:18958680 SERPINE1 Human indometacin multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in decreased expression of SERPINE1 mRNA more ... CTD PMID:16320596 and PMID:28628672 SERPINE1 Human indometacin increases expression EXP 6480464 Indomethacin results in increased expression of SERPINE1 mRNA CTD PMID:16984733 SERPINE1 Human ionomycin increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Ionomycin results in increased expression of SERPINE1 mRNA CTD PMID:15961275 SERPINE1 Human iron(III) citrate decreases expression EXP 6480464 ferric citrate results in decreased expression of SERPINE1 mRNA CTD PMID:29959986 SERPINE1 Human isobutanol multiple interactions EXP 6480464 [[Gasoline co-treated with isobutyl alcohol] results in increased abundance of [Particulate Matter co-treated with Polycyclic Aromatic Hydrocarbons]] which results in increased expression of SERPINE1 mRNA CTD PMID:29432896 SERPINE1 Human isoprenaline increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Isoproterenol results in increased expression of SERPINE1 mRNA CTD PMID:20211217 and PMID:23558518 SERPINE1 Human isoprenaline decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 Isoproterenol results in decreased expression of SERPINE1 protein CTD PMID:24286936 SERPINE1 Human isorhamnetin multiple interactions EXP 6480464 3-methylquercetin inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA] more ... CTD PMID:27151496 SERPINE1 Human isorhamnetin multiple interactions ISO Serpine1 (Mus musculus) 6480464 3-methylquercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of SERPINE1 protein] more ... CTD PMID:27151496 SERPINE1 Human isotretinoin decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 Isotretinoin results in decreased expression of SERPINE1 mRNA CTD PMID:15972972 SERPINE1 Human ivermectin decreases expression ISO Serpine1 (Mus musculus) 6480464 Ivermectin results in decreased expression of SERPINE1 mRNA CTD PMID:28942281 SERPINE1 Human kainic acid increases expression ISO Serpine1 (Mus musculus) 6480464 Kainic Acid results in increased expression of SERPINE1 mRNA CTD PMID:15850565 SERPINE1 Human kainic acid multiple interactions ISO Serpine1 (Mus musculus) 6480464 Guanethidine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA] more ... CTD PMID:15850565 SERPINE1 Human L-ascorbic acid multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Ascorbic Acid promotes the reaction [Vitamin E inhibits the reaction [Endosulfan results in increased activity of SERPINE1 protein]] CTD PMID:21804306 SERPINE1 Human L-methionine multiple interactions ISO Serpine1 (Mus musculus) 6480464 3 more ... CTD PMID:19593819 more ... SERPINE1 Human lactacystin multiple interactions EXP 6480464 lactacystin inhibits the reaction [tin protoporphyrin IX inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 protein]] CTD PMID:18344023 SERPINE1 Human lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of SERPINE1 mRNA CTD PMID:27562236 and PMID:38568856 SERPINE1 Human leflunomide increases expression EXP 6480464 leflunomide results in increased expression of SERPINE1 mRNA CTD PMID:28988120 SERPINE1 Human levonorgestrel multiple interactions EXP 6480464 [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased activity of SERPINE1 protein and [Ethinyl Estradiol co-treated with Levonorgestrel] results in decreased expression of SERPINE1 protein CTD PMID:14981370 more ... SERPINE1 Human linoleic acid increases expression ISO Serpine1 (Mus musculus) 6480464 Linoleic Acid results in increased expression of SERPINE1 mRNA CTD PMID:17374693 SERPINE1 Human lipoic acid multiple interactions ISO Serpine1 (Mus musculus) 6480464 Thioctic Acid inhibits the reaction [Silicon results in increased expression of SERPINE1 protein] CTD PMID:34252510 SERPINE1 Human lipopolysaccharide affects expression EXP 6480464 Lipopolysaccharides affects the expression of SERPINE1 mRNA CTD PMID:28070326 SERPINE1 Human lipopolysaccharide increases expression ISO Serpine1 (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of SERPINE1 mRNA and Lipopolysaccharides results in increased expression of SERPINE1 protein CTD PMID:19367693 more ... SERPINE1 Human lipopolysaccharide increases secretion EXP 6480464 Lipopolysaccharides results in increased secretion of SERPINE1 protein CTD PMID:16320596 and PMID:17513194 SERPINE1 Human lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of SERPINE1 mRNA and Lipopolysaccharides results in increased expression of SERPINE1 protein CTD PMID:16317058 more ... SERPINE1 Human lipopolysaccharide multiple interactions EXP 6480464 [NAT10 protein affects the susceptibility to Lipopolysaccharides] which affects the expression of SERPINE1 mRNA more ... CTD PMID:16317058 more ... SERPINE1 Human lipopolysaccharide multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 17-(dimethylaminoethylamino)-17-demethoxygeldanamycin inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINE1 protein] more ... CTD PMID:16401727 more ... SERPINE1 Human lipopolysaccharide multiple interactions ISO Serpine1 (Mus musculus) 6480464 [procyanidin B3 co-treated with Eicosapentaenoic Acid] inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA] more ... CTD PMID:19367693 more ... SERPINE1 Human lipopolysaccharide increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Lipopolysaccharides results in increased expression of SERPINE1 mRNA and Lipopolysaccharides results in increased expression of SERPINE1 protein CTD PMID:11779202 more ... SERPINE1 Human magnesium atom increases stability EXP 6480464 Magnesium results in increased stability of SERPINE1 protein CTD PMID:21280127 and PMID:21280128 SERPINE1 Human magnesium dichloride multiple interactions EXP 6480464 Magnesium Chloride affects the reaction [Nickel binds to SERPINE1 protein] CTD PMID:21280128 SERPINE1 Human manganese atom increases stability EXP 6480464 Manganese results in increased stability of SERPINE1 protein CTD PMID:21280127 and PMID:21280128 SERPINE1 Human manganese(0) increases stability EXP 6480464 Manganese results in increased stability of SERPINE1 protein CTD PMID:21280127 and PMID:21280128 SERPINE1 Human manganese(II) chloride increases expression ISO Serpine1 (Rattus norvegicus) 6480464 manganese chloride results in increased expression of SERPINE1 mRNA CTD PMID:28801915 SERPINE1 Human manganese(II) chloride decreases methylation ISO Serpine1 (Rattus norvegicus) 6480464 manganese chloride results in decreased methylation of SERPINE1 gene CTD PMID:28801915 SERPINE1 Human mangiferin multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 mangiferin inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA] CTD PMID:19706694 SERPINE1 Human Mecamylamine multiple interactions ISO Serpine1 (Mus musculus) 6480464 Mecamylamine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA] CTD PMID:15850565 SERPINE1 Human medroxyprogesterone acetate increases expression EXP 6480464 Medroxyprogesterone Acetate results in increased expression of SERPINE1 mRNA and Medroxyprogesterone Acetate results in increased expression of SERPINE1 protein CTD PMID:16011840 and PMID:20843944 SERPINE1 Human meglumine amidotrizoate multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of SERPINE1 protein and CTF1 protein inhibits the reaction [[Diatrizoate Meglumine co-treated with Gentamicins] results in increased expression of SERPINE1 protein] CTD PMID:23335628 SERPINE1 Human mercury dibromide increases expression EXP 6480464 mercuric bromide results in increased expression of SERPINE1 mRNA CTD PMID:26272509 SERPINE1 Human mercury dibromide multiple interactions EXP 6480464 [NOG protein co-treated with mercuric bromide co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SERPINE1 mRNA CTD PMID:27188386 SERPINE1 Human mercury dichloride increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Mercuric Chloride results in increased expression of SERPINE1 mRNA and Mercuric Chloride results in increased expression of SERPINE1 protein CTD PMID:11817102 and PMID:14620542 SERPINE1 Human mercury dichloride increases expression EXP 6480464 Mercuric Chloride results in increased expression of SERPINE1 mRNA CTD PMID:38568856 SERPINE1 Human mercury dichloride multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Tacrolimus inhibits the reaction [Mercuric Chloride results in increased expression of SERPINE1 protein] CTD PMID:14620542 SERPINE1 Human metaproterenol increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Metaproterenol results in increased expression of SERPINE1 mRNA CTD PMID:23558518 SERPINE1 Human metformin multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Metformin inhibits the reaction [Fructose results in increased expression of SERPINE1 protein] CTD PMID:25108154 SERPINE1 Human methamphetamine increases expression ISO Serpine1 (Mus musculus) 6480464 Methamphetamine results in increased expression of SERPINE1 mRNA CTD PMID:12766323 SERPINE1 Human methapyrilene increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Methapyrilene results in increased expression of SERPINE1 mRNA CTD PMID:28935588 SERPINE1 Human methimazole increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Methimazole results in increased expression of SERPINE1 mRNA CTD PMID:22504374 SERPINE1 Human methotrexate increases expression EXP 6480464 Methotrexate results in increased expression of SERPINE1 mRNA CTD PMID:31170432 SERPINE1 Human methotrexate multiple interactions EXP 6480464 Folic Acid inhibits the reaction [Methotrexate results in increased expression of SERPINE1 mRNA] CTD PMID:31170432 SERPINE1 Human methyl beta-cyclodextrin multiple interactions EXP 6480464 methyl-beta-cyclodextrin inhibits the reaction [pentabromophenol inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 mRNA]] CTD PMID:28230093 SERPINE1 Human methyl methanesulfonate increases expression EXP 6480464 Methyl Methanesulfonate results in increased expression of SERPINE1 mRNA CTD PMID:23649840 SERPINE1 Human methylmercury chloride increases expression EXP 6480464 methylmercuric chloride results in increased expression of SERPINE1 mRNA CTD PMID:28001369 SERPINE1 Human methylparaben decreases expression EXP 6480464 methylparaben results in decreased expression of SERPINE1 mRNA CTD PMID:31745603 SERPINE1 Human methylparaben increases expression EXP 6480464 methylparaben results in increased expression of SERPINE1 mRNA CTD PMID:38568856 SERPINE1 Human metyrapone multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [[Air Pollutants results in increased abundance of Ozone] which co-treated with Metyrapone] results in increased expression of SERPINE1 mRNA CTD PMID:37088303 SERPINE1 Human mifepristone decreases expression EXP 6480464 Mifepristone results in decreased expression of SERPINE1 mRNA CTD PMID:17584828 SERPINE1 Human mifepristone decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 Mifepristone results in decreased expression of SERPINE1 mRNA CTD PMID:25972201 SERPINE1 Human mifepristone multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Mifepristone promotes the reaction [IL1B protein results in increased expression of SERPINE1 protein] CTD PMID:15963473 SERPINE1 Human mitomycin C affects response to substance EXP 6480464 SERPINE1 protein affects the susceptibility to Mitomycin CTD PMID:16217747 SERPINE1 Human mitomycin C increases expression EXP 6480464 Mitomycin results in increased expression of SERPINE1 protein CTD PMID:34624459 SERPINE1 Human mitoxantrone increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Mitoxantrone results in increased expression of SERPINE1 mRNA CTD PMID:23558518 SERPINE1 Human mono(2-ethylhexyl) phthalate increases expression EXP 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of SERPINE1 mRNA CTD PMID:36695872 SERPINE1 Human monocrotaline multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Monocrotaline co-treated with 15-Hydroxy-11 alpha more ... CTD PMID:21224054 and PMID:31470032 SERPINE1 Human Muraglitazar increases expression ISO Serpine1 (Rattus norvegicus) 6480464 muraglitazar results in increased expression of SERPINE1 mRNA CTD PMID:21515302 SERPINE1 Human N-acetylsphingosine multiple interactions EXP 6480464 [N-acetylsphingosine results in increased abundance of Ceramides] which results in decreased secretion of SERPINE1 protein CTD PMID:11107162 SERPINE1 Human N-methyl-N'-nitro-N-nitrosoguanidine increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Methylnitronitrosoguanidine results in increased expression of SERPINE1 mRNA CTD PMID:15120970 SERPINE1 Human N-nitrosodiethylamine multiple interactions ISO Serpine1 (Mus musculus) 6480464 AHR protein inhibits the reaction [Diethylnitrosamine results in increased expression of SERPINE1 mRNA] more ... CTD PMID:18282651 more ... SERPINE1 Human N-nitrosodiethylamine increases expression ISO Serpine1 (Mus musculus) 6480464 Diethylnitrosamine results in increased expression of SERPINE1 mRNA CTD PMID:18282651 more ... SERPINE1 Human N-nitrosodiethylamine multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA more ... CTD PMID:18164116 more ... SERPINE1 Human N-nitrosodiethylamine affects expression ISO Serpine1 (Mus musculus) 6480464 Diethylnitrosamine affects the expression of SERPINE1 protein CTD PMID:33290806 SERPINE1 Human N-Nitrosopyrrolidine increases expression EXP 6480464 N-Nitrosopyrrolidine results in increased expression of SERPINE1 mRNA CTD PMID:32234424 SERPINE1 Human N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SERPINE1 mRNA more ... CTD PMID:16401727 more ... SERPINE1 Human naphthalene increases expression ISO Serpine1 (Mus musculus) 6480464 naphthalene results in increased expression of SERPINE1 mRNA CTD PMID:18978301 SERPINE1 Human naphthalenes increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Naphthalenes results in increased expression of SERPINE1 protein CTD PMID:17337753 SERPINE1 Human nefazodone multiple interactions EXP 6480464 [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in increased expression of SERPINE1 mRNA CTD PMID:32152650 SERPINE1 Human nefazodone increases expression EXP 6480464 nefazodone results in increased expression of SERPINE1 mRNA CTD PMID:32152650 SERPINE1 Human nickel atom multiple interactions EXP 6480464 HIF1A protein promotes the reaction [Nickel results in increased expression of SERPINE1 mRNA] more ... CTD PMID:11504687 more ... SERPINE1 Human nickel atom increases expression EXP 6480464 Nickel results in increased expression of SERPINE1 mRNA CTD PMID:11504687 more ... SERPINE1 Human nickel atom decreases stability EXP 6480464 Nickel results in decreased stability of SERPINE1 protein CTD PMID:21280127 SERPINE1 Human nickel dichloride affects expression ISO Serpine1 (Rattus norvegicus) 6480464 nickel chloride affects the expression of SERPINE1 mRNA CTD PMID:22110744 SERPINE1 Human nickel dichloride affects expression EXP 6480464 nickel chloride affects the expression of SERPINE1 mRNA CTD PMID:33774146 SERPINE1 Human nickel subsulfide increases expression EXP 6480464 nickel subsulfide results in increased expression of SERPINE1 mRNA CTD PMID:11504688 SERPINE1 Human nickel sulfate increases expression ISO Serpine1 (Mus musculus) 6480464 nickel sulfate results in increased expression of SERPINE1 mRNA CTD PMID:16100012 SERPINE1 Human niclosamide multiple interactions ISO Serpine1 (Mus musculus) 6480464 Niclosamide inhibits the reaction [Doxorubicin results in increased expression of SERPINE1 mRNA] CTD PMID:28318631 SERPINE1 Human nicotine increases secretion ISO Serpine1 (Rattus norvegicus) 6480464 Nicotine results in increased secretion of SERPINE1 protein CTD PMID:21596853 SERPINE1 Human nicotine increases expression EXP 6480464 Nicotine results in increased expression of SERPINE1 mRNA CTD PMID:11166759 SERPINE1 Human nicotinic acid multiple interactions EXP 6480464 Niacin inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 protein] CTD PMID:16916501 SERPINE1 Human nicotinic acid decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 Niacin results in decreased expression of SERPINE1 protein CTD PMID:19420110 SERPINE1 Human nonanedioic acid increases expression EXP 6480464 azelaic acid results in increased expression of SERPINE1 mRNA CTD PMID:8635147 SERPINE1 Human nonanedioic acid multiple interactions EXP 6480464 azelaic acid results in increased expression of and results in increased secretion of SERPINE1 protein CTD PMID:8635147 SERPINE1 Human Nonidet P-40 decreases expression EXP 6480464 Nonidet P-40 results in decreased expression of SERPINE1 mRNA CTD PMID:26552463 SERPINE1 Human norethisterone multiple interactions EXP 6480464 [Ethinyl Estradiol binds to Norethindrone] which results in decreased expression of SERPINE1 protein CTD PMID:14561536 SERPINE1 Human notoginsenoside R1 multiple interactions EXP 6480464 notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA] more ... CTD PMID:16458614 more ... SERPINE1 Human notoginsenoside R1 decreases activity EXP 6480464 notoginsenoside R1 results in decreased activity of SERPINE1 protein CTD PMID:8018658 SERPINE1 Human notoginsenoside R1 multiple interactions ISO Serpine1 (Mus musculus) 6480464 notoginsenoside R1 inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINE1 protein] CTD PMID:9102164 SERPINE1 Human NSC 23766 decreases secretion EXP 6480464 NSC 23766 results in decreased secretion of SERPINE1 protein CTD PMID:36009428 SERPINE1 Human obeticholic acid decreases expression EXP 6480464 obeticholic acid results in decreased expression of SERPINE1 mRNA CTD PMID:27939613 SERPINE1 Human ochratoxin A increases expression ISO Serpine1 (Rattus norvegicus) 6480464 ochratoxin A results in increased expression of SERPINE1 mRNA CTD PMID:19717638 SERPINE1 Human octadecanoic acid multiple interactions ISO Serpine1 (Mus musculus) 6480464 resveratrol inhibits the reaction [stearic acid results in increased expression of SERPINE1 mRNA] CTD PMID:17374693 SERPINE1 Human octadecanoic acid increases expression ISO Serpine1 (Mus musculus) 6480464 stearic acid results in increased expression of SERPINE1 mRNA CTD PMID:17374693 SERPINE1 Human oleic acid multiple interactions EXP 6480464 [Oleic Acid co-treated with INS protein] results in increased expression of SERPINE1 mRNA more ... CTD PMID:11292061 and PMID:30547786 SERPINE1 Human Olmesartan medoxomil decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 Olmesartan Medoxomil results in decreased expression of SERPINE1 mRNA CTD PMID:18501344 SERPINE1 Human orciprenaline increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Metaproterenol results in increased expression of SERPINE1 mRNA CTD PMID:23558518 SERPINE1 Human oxaliplatin multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of SERPINE1 mRNA CTD PMID:25729387 SERPINE1 Human ozone increases expression EXP 6480464 Ozone results in increased expression of SERPINE1 mRNA CTD PMID:27206323 SERPINE1 Human ozone multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in increased expression of SERPINE1 mRNA CTD PMID:34911549 SERPINE1 Human ozone increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Ozone results in increased expression of SERPINE1 mRNA CTD PMID:20980218 and PMID:33217375 SERPINE1 Human ozone increases expression ISO Serpine1 (Mus musculus) 6480464 Ozone results in increased expression of SERPINE1 mRNA CTD PMID:19555225 SERPINE1 Human ozone multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [[Air Pollutants results in increased abundance of Ozone] which co-treated with Metyrapone] results in increased expression of SERPINE1 mRNA more ... CTD PMID:18636392 more ... SERPINE1 Human p-chloromercuribenzoic acid increases expression EXP 6480464 p-Chloromercuribenzoic Acid results in increased expression of SERPINE1 mRNA CTD PMID:26272509 SERPINE1 Human p-chloromercuribenzoic acid multiple interactions EXP 6480464 [NOG protein co-treated with p-Chloromercuribenzoic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SERPINE1 mRNA CTD PMID:27188386 SERPINE1 Human paclitaxel affects response to substance EXP 6480464 SERPINE1 protein affects the susceptibility to Paclitaxel CTD PMID:16217747 SERPINE1 Human palbociclib increases expression EXP 6480464 palbociclib results in increased expression of SERPINE1 mRNA CTD PMID:22869556 SERPINE1 Human paracetamol multiple interactions ISO Serpine1 (Mus musculus) 6480464 caffeic acid inhibits the reaction [Acetaminophen results in increased expression of SERPINE1 protein] more ... CTD PMID:18469330 more ... SERPINE1 Human paracetamol increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Acetaminophen results in increased expression of SERPINE1 mRNA CTD PMID:33387578 SERPINE1 Human paracetamol multiple interactions EXP 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Acetaminophen] results in increased expression of SERPINE1 mRNA CTD PMID:33819548 SERPINE1 Human paracetamol increases response to substance ISO Serpine1 (Mus musculus) 6480464 SERPINE1 gene mutant form results in increased susceptibility to Acetaminophen CTD PMID:22507835 SERPINE1 Human paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of SERPINE1 mRNA CTD PMID:21420995 and PMID:29067470 SERPINE1 Human paracetamol decreases response to substance ISO Serpine1 (Mus musculus) 6480464 SERPINE1 protein results in decreased susceptibility to Acetaminophen CTD PMID:18469330 SERPINE1 Human paracetamol affects expression ISO Serpine1 (Mus musculus) 6480464 Acetaminophen affects the expression of SERPINE1 mRNA CTD PMID:17562736 SERPINE1 Human paracetamol increases expression ISO Serpine1 (Mus musculus) 6480464 Acetaminophen results in increased expression of SERPINE1 mRNA and Acetaminophen results in increased expression of SERPINE1 protein CTD PMID:11264010 more ... SERPINE1 Human paraquat increases expression EXP 6480464 Paraquat results in increased expression of SERPINE1 mRNA CTD PMID:20883675 more ... SERPINE1 Human paraquat increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Paraquat results in increased expression of SERPINE1 mRNA CTD PMID:32680482 SERPINE1 Human paricalcitol multiple interactions EXP 6480464 [Phosphorus co-treated with paricalcitol] affects the expression of SERPINE1 mRNA and [Phosphorus co-treated with paricalcitol] results in decreased expression of SERPINE1 protein CTD PMID:17715259 SERPINE1 Human pazopanib increases expression EXP 6480464 pazopanib results in increased expression of SERPINE1 mRNA and pazopanib results in increased expression of SERPINE1 protein CTD PMID:38613465 SERPINE1 Human pazopanib multiple interactions EXP 6480464 NFE2L2 protein affects the reaction [pazopanib results in increased expression of SERPINE1 mRNA] and NFE2L2 protein affects the reaction [pazopanib results in increased expression of SERPINE1 protein] CTD PMID:38613465 SERPINE1 Human pentane-2,3-dione increases expression ISO Serpine1 (Rattus norvegicus) 6480464 2 and 3-pentanedione results in increased expression of SERPINE1 mRNA CTD PMID:25710175 SERPINE1 Human Pentoxifylline multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Pentoxifylline inhibits the reaction [Ranitidine promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE1 protein]] CTD PMID:17698507 SERPINE1 Human perfluorobutyric acid increases expression ISO Serpine1 (Mus musculus) 6480464 perfluorobutyric acid results in increased expression of SERPINE1 mRNA CTD PMID:34474067 SERPINE1 Human perfluorohexanesulfonic acid increases expression ISO Serpine1 (Mus musculus) 6480464 perfluorohexanesulfonic acid results in increased expression of SERPINE1 mRNA CTD PMID:38458531 SERPINE1 Human perfluorononanoic acid increases expression EXP 6480464 perfluoro-n-nonanoic acid results in increased expression of SERPINE1 mRNA CTD PMID:32588087 SERPINE1 Human perfluorooctane-1-sulfonic acid affects expression ISO Serpine1 (Mus musculus) 6480464 perfluorooctane sulfonic acid affects the expression of SERPINE1 mRNA CTD PMID:19429403 SERPINE1 Human perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of SERPINE1 mRNA CTD PMID:33772556 SERPINE1 Human perfluorooctane-1-sulfonic acid increases expression ISO Serpine1 (Mus musculus) 6480464 perfluorooctane sulfonic acid results in increased expression of SERPINE1 mRNA CTD PMID:20936131 SERPINE1 Human perfluorooctane-1-sulfonic acid multiple interactions ISO Serpine1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with 3 more ... CTD PMID:33096110 and PMID:36331819 SERPINE1 Human perfluorooctanoic acid affects expression ISO Serpine1 (Mus musculus) 6480464 perfluorooctanoic acid affects the expression of SERPINE1 mRNA CTD PMID:19429403 SERPINE1 Human perfluorooctanoic acid increases expression EXP 6480464 perfluorooctanoic acid results in increased expression of SERPINE1 mRNA CTD PMID:25868421 and PMID:33772556 SERPINE1 Human perfluorooctanoic acid multiple interactions ISO Serpine1 (Mus musculus) 6480464 PPARA protein promotes the reaction [perfluorooctanoic acid results in increased expression of SERPINE1 mRNA] CTD PMID:18467677 and PMID:20936131 SERPINE1 Human perfluorooctanoic acid increases expression ISO Serpine1 (Mus musculus) 6480464 perfluorooctanoic acid results in increased expression of SERPINE1 mRNA CTD PMID:18467677 and PMID:20936131 SERPINE1 Human perfluoropentanoic acid increases expression ISO Serpine1 (Mus musculus) 6480464 perfluoropentanoic acid results in increased expression of SERPINE1 mRNA CTD PMID:36435305 SERPINE1 Human Phenelzine decreases expression ISO Serpine1 (Mus musculus) 6480464 Phenelzine results in decreased expression of SERPINE1 mRNA CTD PMID:31249575 SERPINE1 Human phenethyl isothiocyanate increases expression EXP 6480464 phenethyl isothiocyanate results in increased expression of SERPINE1 mRNA CTD PMID:26678675 SERPINE1 Human phenformin decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 Phenformin results in decreased expression of SERPINE1 mRNA CTD PMID:31324951 SERPINE1 Human phenobarbital decreases expression ISO Serpine1 (Mus musculus) 6480464 Phenobarbital results in decreased expression of SERPINE1 mRNA CTD PMID:19270015 SERPINE1 Human phentolamine multiple interactions ISO Serpine1 (Mus musculus) 6480464 Phentolamine inhibits the reaction [Kainic Acid results in increased expression of SERPINE1 mRNA] CTD PMID:15850565 SERPINE1 Human phenylephrine increases expression ISO Serpine1 (Mus musculus) 6480464 Phenylephrine results in increased expression of SERPINE1 mRNA CTD PMID:15850565 SERPINE1 Human phenylephrine increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Phenylephrine results in increased expression of SERPINE1 mRNA CTD PMID:15808835 SERPINE1 Human phenylmercury acetate increases expression EXP 6480464 Phenylmercuric Acetate results in increased expression of SERPINE1 mRNA CTD PMID:26272509 SERPINE1 Human phenylmercury acetate multiple interactions EXP 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SERPINE1 mRNA CTD PMID:27188386 SERPINE1 Human phenytoin multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of SERPINE1 mRNA CTD PMID:21224054 SERPINE1 Human phorbol 13-acetate 12-myristate multiple interactions ISO Serpine1 (Mus musculus) 6480464 [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 mRNA and [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 protein CTD PMID:16368122 SERPINE1 Human phorbol 13-acetate 12-myristate increases secretion EXP 6480464 Tetradecanoylphorbol Acetate results in increased secretion of SERPINE1 protein CTD PMID:35001170 SERPINE1 Human phorbol 13-acetate 12-myristate increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Tetradecanoylphorbol Acetate results in increased expression of SERPINE1 mRNA CTD PMID:12409145 SERPINE1 Human phorbol 13-acetate 12-myristate multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SERPINE1 mRNA] and bisindolylmaleimide I inhibits the reaction [Tetradecanoylphorbol Acetate results in increased expression of SERPINE1 mRNA] CTD PMID:12409145 SERPINE1 Human phorbol 13-acetate 12-myristate multiple interactions EXP 6480464 [indirubin-3'-monoxime co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 mRNA and [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of SERPINE1 protein CTD PMID:18958680 and PMID:35001170 SERPINE1 Human phosgene affects expression ISO Serpine1 (Mus musculus) 6480464 Phosgene affects the expression of SERPINE1 mRNA CTD PMID:16300373 SERPINE1 Human phosphane increases expression ISO Serpine1 (Rattus norvegicus) 6480464 phosphine results in increased expression of SERPINE1 mRNA CTD PMID:34427094 SERPINE1 Human phosphorus atom multiple interactions EXP 6480464 [Phosphorus co-treated with paricalcitol] affects the expression of SERPINE1 mRNA and [Phosphorus co-treated with paricalcitol] results in decreased expression of SERPINE1 protein CTD PMID:17715259 SERPINE1 Human phosphorus(.) multiple interactions EXP 6480464 [Phosphorus co-treated with paricalcitol] affects the expression of SERPINE1 mRNA and [Phosphorus co-treated with paricalcitol] results in decreased expression of SERPINE1 protein CTD PMID:17715259 SERPINE1 Human Phytolaccoside E increases secretion EXP 6480464 esculentoside A results in increased secretion of SERPINE1 protein CTD PMID:36460195 SERPINE1 Human pioglitazone multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 pioglitazone inhibits the reaction [Puromycin Aminonucleoside results in increased expression of SERPINE1 mRNA] CTD PMID:16598202 SERPINE1 Human pioglitazone increases expression EXP 6480464 pioglitazone results in increased expression of SERPINE1 mRNA CTD PMID:21757225 SERPINE1 Human pirfenidone multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 pirfenidone inhibits the reaction [Carbon Tetrachloride results in increased expression of SERPINE1 mRNA] CTD PMID:12445421 SERPINE1 Human pirfenidone multiple interactions ISO Serpine1 (Mus musculus) 6480464 pirfenidone inhibits the reaction [Acetaminophen results in increased expression of SERPINE1 mRNA] CTD PMID:34890640 SERPINE1 Human pirinixic acid multiple interactions ISO Serpine1 (Mus musculus) 6480464 [pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of SERPINE1 mRNA more ... CTD PMID:19593819 more ... SERPINE1 Human pirinixic acid increases secretion EXP 6480464 pirinixic acid results in increased secretion of SERPINE1 protein CTD PMID:10364093 SERPINE1 Human pirinixic acid increases expression EXP 6480464 pirinixic acid results in increased expression of SERPINE1 mRNA CTD PMID:10364093 SERPINE1 Human pirinixic acid increases expression ISO Serpine1 (Mus musculus) 6480464 pirinixic acid results in increased expression of SERPINE1 mRNA CTD PMID:17118139 and PMID:20813756 SERPINE1 Human poly(I:C) increases expression EXP 6480464 Poly I-C results in increased expression of SERPINE1 mRNA and Poly I-C results in increased expression of SERPINE1 protein CTD PMID:30341573 SERPINE1 Human poly(I:C) multiple interactions EXP 6480464 Chloroquine inhibits the reaction [Poly I-C results in increased expression of SERPINE1 mRNA] more ... CTD PMID:30341573 SERPINE1 Human potassium chloride increases secretion ISO Serpine1 (Rattus norvegicus) 6480464 Potassium Chloride results in increased secretion of SERPINE1 protein CTD PMID:21596853 SERPINE1 Human potassium dichromate decreases expression EXP 6480464 Potassium Dichromate results in decreased expression of SERPINE1 protein CTD PMID:23718831 SERPINE1 Human procyanidin B3 multiple interactions ISO Serpine1 (Mus musculus) 6480464 [procyanidin B3 co-treated with Eicosapentaenoic Acid] inhibits the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA] CTD PMID:22169119 SERPINE1 Human progesterone multiple interactions EXP 6480464 [Progesterone co-treated with Estradiol] results in increased expression of SERPINE1 mRNA CTD PMID:17404688 SERPINE1 Human progesterone multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Progesterone inhibits the reaction [Fructose results in increased expression of SERPINE1 mRNA] and Progesterone inhibits the reaction [Fructose results in increased expression of SERPINE1 protein] CTD PMID:23016136 SERPINE1 Human progesterone increases expression EXP 6480464 Progesterone results in increased expression of SERPINE1 mRNA CTD PMID:17404688 more ... SERPINE1 Human propanal increases expression EXP 6480464 propionaldehyde results in increased expression of SERPINE1 mRNA CTD PMID:26079696 SERPINE1 Human pyrrolidine dithiocarbamate multiple interactions EXP 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [RAC1 protein inhibits the reaction [Oxygen deficiency results in increased expression of SERPINE1 mRNA]] more ... CTD PMID:12719791 SERPINE1 Human pyrrolidine dithiocarbamate increases expression EXP 6480464 pyrrolidine dithiocarbamic acid results in increased expression of SERPINE1 mRNA CTD PMID:12719791 SERPINE1 Human quercetin multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [Quercetin results in decreased expression of SERPINE1 mRNA] and U 0126 inhibits the reaction [Quercetin results in decreased expression of SERPINE1 mRNA] CTD PMID:17379280 SERPINE1 Human quercetin increases expression EXP 6480464 Quercetin results in increased expression of SERPINE1 mRNA CTD PMID:21632981 SERPINE1 Human quercetin decreases expression EXP 6480464 Quercetin results in decreased expression of SERPINE1 mRNA CTD PMID:17379280 SERPINE1 Human quercetin 3-O-beta-D-glucofuranoside multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA] CTD PMID:20045035 SERPINE1 Human quercetin 3-O-beta-D-glucopyranoside multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 isoquercitrin inhibits the reaction [[Diethylnitrosamine co-treated with beta-Naphthoflavone] results in increased expression of SERPINE1 mRNA] CTD PMID:20045035 SERPINE1 Human quinolin-8-ol decreases expression EXP 6480464 Oxyquinoline results in decreased expression of SERPINE1 mRNA CTD PMID:21632981 SERPINE1 Human rac-lactic acid affects expression EXP 6480464 Lactic Acid affects the expression of SERPINE1 mRNA CTD PMID:30851411 SERPINE1 Human raloxifene multiple interactions EXP 6480464 [Raloxifene Hydrochloride co-treated with ESR2 protein] results in increased expression of SERPINE1 mRNA CTD PMID:19059307 SERPINE1 Human raloxifene decreases expression EXP 6480464 Raloxifene Hydrochloride results in decreased expression of SERPINE1 protein CTD PMID:15850603 SERPINE1 Human raloxifene increases expression EXP 6480464 Raloxifene Hydrochloride results in increased expression of SERPINE1 protein CTD PMID:16277677 SERPINE1 Human ranitidine multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [Lipopolysaccharides co-treated with Ranitidine] results in increased expression of SERPINE1 mRNA more ... CTD PMID:16401727 more ... SERPINE1 Human reserpine multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of SERPINE1 mRNA and [troglitazone co-treated with [Hydrochlorothiazide co-treated with Hydralazine co-treated with Reserpine]] results in decreased expression of SERPINE1 protein CTD PMID:11318962 SERPINE1 Human resveratrol multiple interactions ISO Serpine1 (Mus musculus) 6480464 resveratrol inhibits the reaction [stearic acid results in increased expression of SERPINE1 mRNA] more ... CTD PMID:17374693 and PMID:17967414 SERPINE1 Human resveratrol multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 resveratrol inhibits the reaction [Fructose results in increased expression of SERPINE1 protein] CTD PMID:25108154 SERPINE1 Human resveratrol decreases expression EXP 6480464 resveratrol results in decreased expression of SERPINE1 mRNA and resveratrol results in decreased expression of SERPINE1 protein CTD PMID:23224687 and PMID:23819014 SERPINE1 Human resveratrol affects secretion EXP 6480464 resveratrol affects the secretion of SERPINE1 protein CTD PMID:24802182 SERPINE1 Human resveratrol multiple interactions EXP 6480464 LPIN1 affects the reaction [resveratrol inhibits the reaction [TGFB1 protein results in increased expression of SERPINE1 protein]] more ... CTD PMID:20531350 and PMID:27345520 SERPINE1 Human resveratrol increases expression EXP 6480464 resveratrol results in increased expression of SERPINE1 mRNA and resveratrol results in increased expression of SERPINE1 protein CTD PMID:15280659 and PMID:23437203 SERPINE1 Human rifampicin multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in increased expression of SERPINE1 mRNA CTD PMID:21224054 SERPINE1 Human rifampicin multiple interactions EXP 6480464 [Rifampin co-treated with NR1I2 protein] results in increased expression of SERPINE1 mRNA CTD PMID:21127053 SERPINE1 Human rimonabant decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 Rimonabant results in decreased expression of SERPINE1 protein CTD PMID:17882151 SERPINE1 Human rosmarinic acid decreases expression EXP 6480464 Rosmarinic Acid results in decreased expression of SERPINE1 mRNA CTD PMID:26804033 SERPINE1 Human rosmarinic acid decreases expression ISO Serpine1 (Mus musculus) 6480464 Rosmarinic Acid results in decreased expression of SERPINE1 mRNA CTD PMID:26804033 SERPINE1 Human rotenone increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Rotenone results in increased expression of SERPINE1 mRNA CTD PMID:27900601 SERPINE1 Human rotenone affects expression ISO Serpine1 (Rattus norvegicus) 6480464 Rotenone affects the expression of SERPINE1 mRNA CTD PMID:28374803 SERPINE1 Human S-butyl-DL-homocysteine (S,R)-sulfoximine increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Buthionine Sulfoximine results in increased expression of SERPINE1 mRNA CTD PMID:23939143 SERPINE1 Human salvianolic acid B multiple interactions ISO Serpine1 (Mus musculus) 6480464 salvianolic acid B affects the reaction [Diethylnitrosamine affects the expression of SERPINE1 protein] more ... CTD PMID:33290806 SERPINE1 Human saralasin multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Saralasin inhibits the reaction [AGT protein results in increased activity of SERPINE1 protein] CTD PMID:11244025 SERPINE1 Human SB 203580 multiple interactions ISO Serpine1 (Mus musculus) 6480464 SB 203580 inhibits the reaction [cupric oxide results in increased expression of SERPINE1 mRNA] CTD PMID:20171267 SERPINE1 Human SB 431542 multiple interactions EXP 6480464 4-(5-benzo(1 more ... CTD PMID:22286157 and PMID:27188386 SERPINE1 Human Securinine increases expression EXP 6480464 securinine results in increased expression of SERPINE1 mRNA CTD PMID:32662633 SERPINE1 Human serpentine asbestos decreases expression ISO Serpine1 (Mus musculus) 6480464 Asbestos and Serpentine results in decreased expression of SERPINE1 mRNA CTD PMID:23917077 SERPINE1 Human serpentine asbestos increases expression ISO Serpine1 (Mus musculus) 6480464 Asbestos and Serpentine results in increased expression of SERPINE1 mRNA CTD PMID:23917077 SERPINE1 Human Shikonin multiple interactions ISO Serpine1 (Mus musculus) 6480464 shikonin inhibits the reaction [Antigen-Antibody Complex results in increased expression of SERPINE1 mRNA] CTD PMID:25451590 SERPINE1 Human silicon atom increases expression ISO Serpine1 (Mus musculus) 6480464 Silicon results in increased expression of SERPINE1 protein CTD PMID:34252510 SERPINE1 Human silicon atom multiple interactions ISO Serpine1 (Mus musculus) 6480464 Thioctic Acid inhibits the reaction [Silicon results in increased expression of SERPINE1 protein] CTD PMID:34252510 SERPINE1 Human silicon dioxide affects secretion EXP 6480464 Silicon Dioxide analog affects the secretion of SERPINE1 protein CTD PMID:25895662 SERPINE1 Human silicon dioxide multiple interactions ISO Serpine1 (Mus musculus) 6480464 LIAS protein promotes the reaction [Silicon Dioxide results in increased expression of SERPINE1 protein] CTD PMID:32017981 SERPINE1 Human silicon dioxide multiple interactions EXP 6480464 [SULF1 mRNA results in increased susceptibility to Silicon Dioxide] which results in increased expression of SERPINE1 mRNA CTD PMID:29673857 SERPINE1 Human silicon dioxide increases expression ISO Serpine1 (Mus musculus) 6480464 Silicon Dioxide results in increased expression of SERPINE1 mRNA and Silicon Dioxide results in increased expression of SERPINE1 protein CTD PMID:19073995 more ... SERPINE1 Human silicon dioxide increases expression EXP 6480464 Silicon Dioxide analog results in increased expression of SERPINE1 mRNA CTD PMID:25895662 SERPINE1 Human silver atom increases expression EXP 6480464 Silver results in increased expression of SERPINE1 mRNA CTD PMID:26014281 and PMID:28959546 SERPINE1 Human silver atom decreases expression EXP 6480464 Silver results in decreased expression of SERPINE1 mRNA CTD PMID:22342292 SERPINE1 Human silver(0) decreases expression EXP 6480464 Silver results in decreased expression of SERPINE1 mRNA CTD PMID:22342292 SERPINE1 Human silver(0) increases expression EXP 6480464 Silver results in increased expression of SERPINE1 mRNA CTD PMID:26014281 and PMID:28959546 SERPINE1 Human simvastatin decreases expression EXP 6480464 Simvastatin results in decreased expression of SERPINE1 mRNA and Simvastatin results in decreased expression of SERPINE1 protein CTD PMID:16375908 more ... SERPINE1 Human simvastatin decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 Simvastatin results in decreased expression of SERPINE1 mRNA CTD PMID:16414398 SERPINE1 Human simvastatin decreases secretion EXP 6480464 Simvastatin results in decreased secretion of SERPINE1 protein CTD PMID:21524281 SERPINE1 Human simvastatin decreases activity EXP 6480464 Simvastatin results in decreased activity of SERPINE1 protein CTD PMID:17513194 SERPINE1 Human simvastatin multiple interactions EXP 6480464 [Simvastatin co-treated with Dexamethasone] results in increased secretion of SERPINE1 protein CTD PMID:21524281 SERPINE1 Human sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [TP73 protein results in decreased expression of SERPINE1 mRNA] CTD PMID:21245298 SERPINE1 Human sirolimus multiple interactions ISO Serpine1 (Mus musculus) 6480464 Sirolimus inhibits the reaction [Ethylene Chlorohydrin promotes the reaction [Lipopolysaccharides results in increased expression of SERPINE1 mRNA]] CTD PMID:31499194 SERPINE1 Human sodium arsenate multiple interactions EXP 6480464 [sodium arsenate results in increased abundance of Arsenic] which results in increased expression of SERPINE1 mRNA CTD PMID:32525701 SERPINE1 Human sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of SERPINE1 mRNA and sodium arsenite results in increased expression of SERPINE1 protein CTD PMID:26535918 more ... SERPINE1 Human sodium arsenite multiple interactions EXP 6480464 [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased secretion of SERPINE1 protein more ... CTD PMID:27286880 more ... SERPINE1 Human sodium arsenite increases expression ISO Serpine1 (Mus musculus) 6480464 sodium arsenite results in increased expression of SERPINE1 protein CTD PMID:16507464 SERPINE1 Human sodium arsenite decreases expression ISO Serpine1 (Mus musculus) 6480464 sodium arsenite results in decreased expression of SERPINE1 mRNA CTD PMID:16014739 SERPINE1 Human sodium arsenite multiple interactions ISO Serpine1 (Mus musculus) 6480464 [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 mRNA and [sodium arsenite co-treated with Tetradecanoylphorbol Acetate] results in increased expression of SERPINE1 protein CTD PMID:16368122 SERPINE1 Human sodium arsenite affects expression ISO Serpine1 (Mus musculus) 6480464 sodium arsenite affects the expression of SERPINE1 mRNA CTD PMID:16507464 SERPINE1 Human sodium dichromate increases expression ISO Serpine1 (Mus musculus) 6480464 sodium bichromate results in increased expression of SERPINE1 mRNA CTD PMID:31558096 SERPINE1 Human sodium dodecyl sulfate increases expression EXP 6480464 Sodium Dodecyl Sulfate results in increased expression of SERPINE1 mRNA CTD PMID:31734321 SERPINE1 Human Soman increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Soman results in increased expression of SERPINE1 mRNA CTD PMID:19281266 SERPINE1 Human sotorasib multiple interactions EXP 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SERPINE1 mRNA CTD PMID:36139627 SERPINE1 Human spironolactone decreases expression EXP 6480464 Spironolactone results in decreased expression of SERPINE1 protein CTD PMID:12424430 SERPINE1 Human streptozocin multiple interactions ISO Serpine1 (Mus musculus) 6480464 SIRT1 protein inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA] more ... CTD PMID:16731828 more ... SERPINE1 Human streptozocin increases expression ISO Serpine1 (Mus musculus) 6480464 Streptozocin results in increased expression of SERPINE1 more ... CTD PMID:16731828 more ... SERPINE1 Human streptozocin increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Streptozocin results in increased expression of SERPINE1 mRNA and Streptozocin results in increased expression of SERPINE1 protein CTD PMID:15322501 more ... SERPINE1 Human streptozocin multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 benazepril inhibits the reaction [Streptozocin results in increased expression of SERPINE1 mRNA] more ... CTD PMID:15322501 more ... SERPINE1 Human succimer multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Succimer binds to Magnetite Nanoparticles] which results in increased expression of SERPINE1 mRNA and [Succimer co-treated with Magnetite Nanoparticles] results in increased expression of SERPINE1 mRNA CTD PMID:21641980 and PMID:26378955 SERPINE1 Human sulforaphane multiple interactions ISO Serpine1 (Mus musculus) 6480464 [NFE2L2 protein affects the susceptibility to sulforaphane] affects the reaction [Oxygen deficiency results in increased expression of SERPINE1 protein] more ... CTD PMID:24967692 more ... SERPINE1 Human sulindac sulfide increases expression EXP 6480464 sulindac sulfide results in increased expression of SERPINE1 mRNA CTD PMID:15897233 SERPINE1 Human sunitinib decreases expression EXP 6480464 Sunitinib results in decreased expression of SERPINE1 mRNA CTD PMID:31533062 SERPINE1 Human Sunset Yellow FCF multiple interactions EXP 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with 6-hydroxy-5-((p- sulfophenyl)azo)-2-naphthalenesulfonic acid disodium salt] results in increased expression of SERPINE1 mRNA CTD PMID:33819548 SERPINE1 Human superoxide multiple interactions EXP 6480464 [[Superoxides co-treated with Hydroxyl Radical] results in increased oxidation of LPA protein] which results in decreased secretion of SERPINE1 protein CTD PMID:11681624 SERPINE1 Human tacrolimus hydrate increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Tacrolimus results in increased expression of SERPINE1 mRNA CTD PMID:21865292 and PMID:9422427 SERPINE1 Human tacrolimus hydrate multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Tacrolimus inhibits the reaction [Mercuric Chloride results in increased expression of SERPINE1 protein] more ... CTD PMID:14620542 and PMID:23825664 SERPINE1 Human tamoxifen decreases expression EXP 6480464 Tamoxifen results in decreased expression of SERPINE1 protein CTD PMID:15850603 SERPINE1 Human tamoxifen multiple interactions EXP 6480464 [Tamoxifen co-treated with ESR2 protein] results in increased expression of SERPINE1 mRNA CTD PMID:19059307 SERPINE1 Human tartrazine multiple interactions EXP 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Tartrazine] results in increased expression of SERPINE1 mRNA CTD PMID:33819548 SERPINE1 Human taurocholic acid multiple interactions ISO Serpine1 (Mus musculus) 6480464 NR1H4 gene mutant form promotes the reaction [Taurocholic Acid results in increased expression of SERPINE1 mRNA] CTD PMID:28505368 SERPINE1 Human telmisartan multiple interactions ISO Serpine1 (Mus musculus) 6480464 telmisartan inhibits the reaction [[AGT protein modified form co-treated with AGTR1A co-treated with AGTR1B] results in increased expression of SERPINE1 mRNA] and telmisartan inhibits the reaction [Hydrogen Peroxide results in increased expression of SERPINE1 mRNA] CTD PMID:17620961 SERPINE1 Human telmisartan multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 telmisartan inhibits the reaction [AGT protein results in increased expression of SERPINE1 mRNA] CTD PMID:19706694 SERPINE1 Human temozolomide decreases expression EXP 6480464 Temozolomide results in decreased expression of SERPINE1 mRNA CTD PMID:31758290 SERPINE1 Human tert-butyl hydroperoxide increases expression EXP 6480464 tert-Butylhydroperoxide results in increased expression of SERPINE1 mRNA CTD PMID:15336504 SERPINE1 Human Tesaglitazar increases expression ISO Serpine1 (Rattus norvegicus) 6480464 tesaglitazar results in increased expression of SERPINE1 mRNA CTD PMID:21515302 SERPINE1 Human testosterone decreases expression ISO Serpine1 (Mus musculus) 6480464 Testosterone results in decreased expression of SERPINE1 mRNA CTD PMID:22138414 SERPINE1 Human testosterone increases expression ISO Serpine1 (Mus musculus) 6480464 Testosterone results in increased expression of SERPINE1 mRNA CTD PMID:15788153 SERPINE1 Human tetrachloromethane multiple interactions ISO Serpine1 (Mus musculus) 6480464 3-methylquercetin inhibits the reaction [Carbon Tetrachloride results in increased expression of SERPINE1 protein] more ... CTD PMID:27151496 and PMID:28505368 SERPINE1 Human tetrachloromethane multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 pirfenidone inhibits the reaction [Carbon Tetrachloride results in increased expression of SERPINE1 mRNA] CTD PMID:12445421 SERPINE1 Human tetrachloromethane decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in decreased expression of SERPINE1 mRNA CTD PMID:16239168 SERPINE1 Human tetrachloromethane increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in increased expression of SERPINE1 mRNA CTD PMID:12445421 SERPINE1 Human tetrachloromethane increases expression ISO Serpine1 (Mus musculus) 6480464 Carbon Tetrachloride results in increased expression of SERPINE1 mRNA and Carbon Tetrachloride results in increased expression of SERPINE1 protein CTD PMID:25566828 more ... SERPINE1 Human tetraphene multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of SERPINE1 mRNA CTD PMID:27858113 SERPINE1 Human thiacloprid multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SERPINE1 mRNA CTD PMID:32745781 SERPINE1 Human thimerosal increases expression EXP 6480464 Thimerosal results in increased expression of SERPINE1 mRNA CTD PMID:16870260 SERPINE1 Human thioacetamide multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of SERPINE1 mRNA CTD PMID:23830814 SERPINE1 Human thioacetamide increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of SERPINE1 mRNA CTD PMID:23558518 and PMID:34492290 SERPINE1 Human thiophanate-methyl multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SERPINE1 mRNA CTD PMID:32745781 SERPINE1 Human thiram increases expression EXP 6480464 Thiram results in increased expression of SERPINE1 mRNA CTD PMID:38568856 SERPINE1 Human tibolone increases expression EXP 6480464 tibolone metabolite results in increased expression of SERPINE1 protein and tibolone results in increased expression of SERPINE1 protein CTD PMID:16011840 SERPINE1 Human titanium dioxide affects expression EXP 6480464 titanium dioxide affects the expression of SERPINE1 mRNA CTD PMID:19695317 SERPINE1 Human titanium dioxide multiple interactions ISO Serpine1 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in decreased expression of SERPINE1 mRNA CTD PMID:29950665 SERPINE1 Human titanium dioxide multiple interactions EXP 6480464 [Silver Compounds binds to [Nitrogen binds to titanium dioxide]] which results in increased secretion of SERPINE1 protein CTD PMID:30711708 SERPINE1 Human titanium dioxide increases expression ISO Serpine1 (Rattus norvegicus) 6480464 titanium dioxide results in increased expression of SERPINE1 mRNA CTD PMID:30012374 SERPINE1 Human titanium dioxide increases expression ISO Serpine1 (Mus musculus) 6480464 titanium dioxide results in increased expression of SERPINE1 mRNA CTD PMID:23557971 SERPINE1 Human titanium dioxide increases expression EXP 6480464 titanium dioxide results in increased expression of SERPINE1 mRNA CTD PMID:22342292 SERPINE1 Human topotecan multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of SERPINE1 mRNA CTD PMID:25729387 SERPINE1 Human topotecan affects response to substance EXP 6480464 SERPINE1 protein affects the susceptibility to Topotecan CTD PMID:16217747 SERPINE1 Human topotecan increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Topotecan results in increased expression of SERPINE1 mRNA CTD PMID:25729387 SERPINE1 Human trametinib multiple interactions EXP 6480464 [sotorasib co-treated with trametinib co-treated with NVP-BKM120] results in decreased expression of SERPINE1 mRNA CTD PMID:36139627 SERPINE1 Human trans-caffeic acid multiple interactions ISO Serpine1 (Mus musculus) 6480464 caffeic acid inhibits the reaction [Acetaminophen results in increased expression of SERPINE1 protein] CTD PMID:27720869 SERPINE1 Human triadimefon decreases expression EXP 6480464 triadimefon results in decreased expression of SERPINE1 mRNA CTD PMID:26705709 SERPINE1 Human triamterene increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Triamterene results in increased expression of SERPINE1 mRNA CTD PMID:23558518 SERPINE1 Human trichloroethene multiple interactions ISO Serpine1 (Mus musculus) 6480464 PPARA protein inhibits the reaction [Trichloroethylene results in decreased expression of SERPINE1 mRNA] CTD PMID:15363585 SERPINE1 Human trichloroethene increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of SERPINE1 mRNA CTD PMID:33387578 SERPINE1 Human trichloroethene increases expression ISO Serpine1 (Mus musculus) 6480464 Trichloroethylene results in increased expression of SERPINE1 mRNA CTD PMID:28973375 SERPINE1 Human trichloroethene affects expression ISO Serpine1 (Mus musculus) 6480464 Trichloroethylene affects the expression of SERPINE1 mRNA CTD PMID:21135412 SERPINE1 Human trichostatin A increases expression EXP 6480464 trichostatin A results in increased expression of SERPINE1 mRNA CTD PMID:26705709 SERPINE1 Human triclosan multiple interactions EXP 6480464 [Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid co-treated with Triclosan] results in increased expression of SERPINE1 mRNA CTD PMID:33819548 SERPINE1 Human triclosan decreases expression EXP 6480464 Triclosan results in decreased expression of SERPINE1 mRNA CTD PMID:34681664 SERPINE1 Human trimellitic anhydride increases expression ISO Serpine1 (Mus musculus) 6480464 trimellitic anhydride results in increased expression of SERPINE1 mRNA CTD PMID:19042947 SERPINE1 Human tris(2-butoxyethyl) phosphate affects expression EXP 6480464 tris(2-butoxyethyl) phosphate affects the expression of SERPINE1 mRNA CTD PMID:29024780 SERPINE1 Human troglitazone multiple interactions EXP 6480464 Genistein promotes the reaction [troglitazone inhibits the reaction [TNF protein results in increased secretion of SERPINE1 protein]] more ... CTD PMID:11292061 and PMID:14534369 SERPINE1 Human troglitazone increases expression ISO Serpine1 (Rattus norvegicus) 6480464 troglitazone results in increased expression of SERPINE1 mRNA CTD PMID:21515302 SERPINE1 Human troglitazone decreases expression EXP 6480464 troglitazone results in decreased expression of SERPINE1 mRNA CTD PMID:10768100 and PMID:19631733 SERPINE1 Human troglitazone increases expression EXP 6480464 troglitazone results in increased expression of SERPINE1 mRNA CTD PMID:19140230 and PMID:19631733 SERPINE1 Human troglitazone decreases secretion EXP 6480464 troglitazone results in decreased secretion of SERPINE1 protein CTD PMID:10768100 SERPINE1 Human troglitazone decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 troglitazone results in decreased expression of SERPINE1 mRNA and troglitazone results in decreased expression of SERPINE1 protein CTD PMID:11318962 SERPINE1 Human troglitazone multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [troglitazone binds to and results in increased activity of PPARG mRNA] which results in decreased expression of SERPINE1 mRNA more ... CTD PMID:11318962 SERPINE1 Human trovafloxacin multiple interactions ISO Serpine1 (Mus musculus) 6480464 [trovafloxacin co-treated with lipopolysaccharide more ... CTD PMID:18930950 and PMID:19367693 SERPINE1 Human trovafloxacin increases expression ISO Serpine1 (Mus musculus) 6480464 trovafloxacin results in increased expression of SERPINE1 mRNA CTD PMID:35537566 SERPINE1 Human undecane increases expression ISO Serpine1 (Rattus norvegicus) 6480464 undecane results in increased expression of SERPINE1 protein CTD PMID:17337753 SERPINE1 Human usnic acid multiple interactions EXP 6480464 [usnic acid co-treated with Lipopolysaccharides] results in decreased expression of SERPINE1 mRNA CTD PMID:22777745 SERPINE1 Human valproic acid decreases methylation EXP 6480464 Valproic Acid results in decreased methylation of SERPINE1 gene CTD PMID:29154799 SERPINE1 Human valproic acid decreases response to substance ISO Serpine1 (Rattus norvegicus) 6480464 SERPINE1 protein results in decreased susceptibility to Valproic Acid CTD PMID:23378038 SERPINE1 Human valproic acid multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [Valproic Acid results in decreased activity of SERPINE1 protein] which results in increased activity of PLAT protein more ... CTD PMID:23378038 SERPINE1 Human valproic acid increases response to substance ISO Serpine1 (Mus musculus) 6480464 SERPINE1 gene mutant form results in increased susceptibility to Valproic Acid CTD PMID:23378038 SERPINE1 Human valproic acid multiple interactions EXP 6480464 [NOG protein co-treated with Valproic Acid co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of SERPINE1 mRNA CTD PMID:27188386 SERPINE1 Human valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of SERPINE1 mRNA CTD PMID:23179753 more ... SERPINE1 Human valproic acid affects expression EXP 6480464 Valproic Acid affects the expression of SERPINE1 mRNA CTD PMID:25979313 SERPINE1 Human valsartan multiple interactions EXP 6480464 Valsartan inhibits the reaction [AGT protein results in increased secretion of SERPINE1 protein] CTD PMID:11244025 SERPINE1 Human valsartan decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 Valsartan results in decreased expression of SERPINE1 mRNA and Valsartan results in decreased expression of SERPINE1 protein CTD PMID:21051829 SERPINE1 Human valsartan multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 [Valsartan co-treated with Fosinopril] results in decreased expression of SERPINE1 mRNA more ... CTD PMID:11244025 and PMID:21051829 SERPINE1 Human vincaleukoblastine increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Vinblastine results in increased expression of SERPINE1 mRNA CTD PMID:20624997 SERPINE1 Human vincaleukoblastine affects response to substance EXP 6480464 SERPINE1 protein affects the susceptibility to Vinblastine CTD PMID:16217747 SERPINE1 Human vinclozolin decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 vinclozolin results in decreased expression of SERPINE1 mRNA CTD PMID:23034163 SERPINE1 Human vincristine increases expression ISO Serpine1 (Rattus norvegicus) 6480464 Vincristine results in increased expression of SERPINE1 mRNA CTD PMID:20624997 SERPINE1 Human vincristine increases response to substance EXP 6480464 SERPINE1 gene SNP results in increased susceptibility to Vincristine CTD PMID:21245421 SERPINE1 Human vitamin E multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Ascorbic Acid promotes the reaction [Vitamin E inhibits the reaction [Endosulfan results in increased activity of SERPINE1 protein]] and Vitamin E inhibits the reaction [Endosulfan results in increased activity of SERPINE1 protein] CTD PMID:21804306 SERPINE1 Human wortmannin multiple interactions EXP 6480464 wortmannin inhibits the reaction [TNF protein results in increased expression of and results in increased secretion of SERPINE1 protein] and wortmannin inhibits the reaction [TNF protein results in increased expression of SERPINE1 mRNA] CTD PMID:16458614 SERPINE1 Human zearalenone multiple interactions EXP 6480464 [Zearalenone co-treated with Aflatoxin B1] results in increased expression of SERPINE1 mRNA CTD PMID:28965971 SERPINE1 Human zinc atom multiple interactions EXP 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of SERPINE1 mRNA CTD PMID:18593933 SERPINE1 Human zinc atom multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Zinc inhibits the reaction [Streptozocin results in increased expression of SERPINE1 protein] CTD PMID:19369054 SERPINE1 Human zinc molecular entity decreases expression EXP 6480464 Zinc Compounds results in decreased expression of SERPINE1 mRNA CTD PMID:24035972 SERPINE1 Human zinc oxide decreases expression ISO Serpine1 (Rattus norvegicus) 6480464 Zinc Oxide results in decreased expression of SERPINE1 protein CTD PMID:33205376 SERPINE1 Human zinc pyrithione decreases expression EXP 6480464 pyrithione zinc results in decreased expression of SERPINE1 mRNA CTD PMID:21424779 SERPINE1 Human zinc(0) multiple interactions EXP 6480464 [PCI 5002 co-treated with Zinc] results in increased expression of SERPINE1 mRNA CTD PMID:18593933 SERPINE1 Human zinc(0) multiple interactions ISO Serpine1 (Rattus norvegicus) 6480464 Zinc inhibits the reaction [Streptozocin results in increased expression of SERPINE1 protein] CTD PMID:19369054 SERPINE1 Human ziram multiple interactions ISO Serpine1 (Mus musculus) 6480464 [Dietary Fats co-treated with 2-chloro-N-(4-chlorobiphenyl-2-yl)nicotinamide co-treated with Captan co-treated with Chlorpyrifos co-treated with thiacloprid co-treated with Thiophanate co-treated with Ziram] results in increased expression of SERPINE1 mRNA CTD PMID:32745781
