Symbol:
MIR301A
Name:
microRNA 301a
RGD ID:
1345841
HGNC Page
HGNC:31622
Description:
Enables mRNA base-pairing translational repressor activity. Involved in miRNA-mediated post-transcriptional gene silencing and positive regulation of vascular associated smooth muscle cell proliferation. Located in extracellular space. Biomarker of Parkinson's disease.
Type:
ncrna (Ensembl: miRNA)
RefSeq Status:
PROVISIONAL
Previously known as:
mir-301a; MIR301; MIRN301; MIRN301A
RGD Orthologs
Alliance Orthologs
More Info
more info ...
More Info
Allele / Splice:
See ClinVar data
Latest Assembly:
GRCh38 - Human Genome Assembly GRCh38
Position:
Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 17 59,151,136 - 59,151,221 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 17 59,151,136 - 59,151,221 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 17 57,228,497 - 57,228,582 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 17 54,583,278 - 54,583,363 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Celera 17 53,691,496 - 53,691,581 (-) NCBI Celera Cytogenetic Map 17 q22 NCBI HuRef 17 52,589,503 - 52,589,588 (-) NCBI HuRef CHM1_1 17 57,293,992 - 57,294,077 (-) NCBI CHM1_1 T2T-CHM13v2.0 17 60,019,234 - 60,019,319 (-) NCBI T2T-CHM13v2.0
JBrowse:
View Region in Genome Browser (JBrowse)
Model
MIR301A Human Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCh38 17 59,151,136 - 59,151,221 (-) NCBI GRCh38 GRCh38 hg38 GRCh38 GRCh38.p14 Ensembl 17 59,151,136 - 59,151,221 (-) Ensembl GRCh38 hg38 GRCh38 GRCh37 17 57,228,497 - 57,228,582 (-) NCBI GRCh37 GRCh37 hg19 GRCh37 Build 36 17 54,583,278 - 54,583,363 (-) NCBI NCBI36 Build 36 hg18 NCBI36 Celera 17 53,691,496 - 53,691,581 (-) NCBI Celera Cytogenetic Map 17 q22 NCBI HuRef 17 52,589,503 - 52,589,588 (-) NCBI HuRef CHM1_1 17 57,293,992 - 57,294,077 (-) NCBI CHM1_1 T2T-CHM13v2.0 17 60,019,234 - 60,019,319 (-) NCBI T2T-CHM13v2.0
Mir301 Mouse Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCm39 11 87,003,830 - 87,003,915 (+) NCBI GRCm39 GRCm39 mm39 GRCm39 Ensembl 11 87,003,830 - 87,003,915 (+) Ensembl GRCm39 Ensembl GRCm38 11 87,113,004 - 87,113,089 (+) NCBI GRCm38 GRCm38 mm10 GRCm38 GRCm38.p6 Ensembl 11 87,113,004 - 87,113,089 (+) Ensembl GRCm38 mm10 GRCm38 MGSCv37 11 86,926,506 - 86,926,591 (+) NCBI GRCm37 MGSCv37 mm9 NCBIm37 Celera 11 96,715,019 - 96,715,104 (+) NCBI Celera Cytogenetic Map 11 C NCBI cM Map 11 51.92 NCBI
Mir301a Rat Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl GRCr8 10 72,422,599 - 72,422,698 (+) NCBI GRCr8 mRatBN7.2 10 71,925,336 - 71,925,435 (+) NCBI mRatBN7.2 mRatBN7.2 mRatBN7.2 Ensembl 10 71,925,336 - 71,925,435 (+) Ensembl mRatBN7.2 Ensembl UTH_Rnor_SHR_Utx 10 76,535,839 - 76,535,938 (+) NCBI Rnor_SHR UTH_Rnor_SHR_Utx UTH_Rnor_SHRSP_BbbUtx_1.0 10 76,040,743 - 76,040,842 (+) NCBI Rnor_SHRSP UTH_Rnor_SHRSP_BbbUtx_1.0 UTH_Rnor_WKY_Bbb_1.0 10 71,505,267 - 71,505,366 (+) NCBI Rnor_WKY UTH_Rnor_WKY_Bbb_1.0 Rnor_6.0 10 74,417,746 - 74,417,845 (+) NCBI Rnor6.0 Rnor_6.0 rn6 Rnor6.0 Rnor_6.0 Ensembl 10 74,417,746 - 74,417,845 (+) Ensembl Rnor6.0 rn6 Rnor6.0 Rnor_5.0 10 75,682,818 - 75,682,917 (-) NCBI Rnor5.0 Rnor_5.0 rn5 Rnor5.0 Celera 10 70,841,530 - 70,841,629 (+) NCBI Celera Cytogenetic Map 10 q26 NCBI
MIR301A Dog Assembly Chr Position (strand) Source Genome Browsers JBrowse NCBI UCSC Ensembl CanFam3.1 9 33,724,572 - 33,724,655 (-) NCBI CanFam3.1 CanFam3.1 canFam3 CanFam3.1 CanFam3.1 Ensembl 9 33,724,571 - 33,724,655 (-) Ensembl CanFam3.1 canFam3 CanFam3.1 Dog10K_Boxer_Tasha 9 32,958,210 - 32,958,293 (-) NCBI Dog10K_Boxer_Tasha ROS_Cfam_1.0 9 34,529,984 - 34,530,067 (-) NCBI ROS_Cfam_1.0 UMICH_Zoey_3.1 9 33,315,731 - 33,315,814 (-) NCBI UMICH_Zoey_3.1 UNSW_CanFamBas_1.0 9 33,604,754 - 33,604,837 (-) NCBI UNSW_CanFamBas_1.0 UU_Cfam_GSD_1.0 9 33,691,434 - 33,691,517 (-) NCBI UU_Cfam_GSD_1.0
.
Confirmed Targets
MEOX2 hsa-miR-301a-3p Mirtarbase external_info Luciferase reporter assay Functional MTI 20470754 MEOX2 hsa-miR-301a-3p Mirtarbase external_info Luciferase reporter assay//qRT-PCR//Western blot Functional MTI 22373864 NKRF hsa-miR-301a-3p Mirtarbase external_info Luciferase reporter assay//Microarray//qRT-PCR//We Functional MTI 21113131 SERPINE1 hsa-miR-301a-3p Mirtarbase external_info Luciferase reporter assay Functional MTI 21175428 SMAD4 hsa-miR-301a-3p Mirtarbase external_info Luciferase reporter assay Functional MTI 23393589 RUNX3 hsa-miR-301a-3p Mirtarbase external_info Luciferase reporter assay//qRT-PCR//Western blot Functional MTI 23338485 CEP192 hsa-miR-301a-3p Mirtarbase external_info CLASH Functional MTI (Weak) 23622248 SMAD4 hsa-miR-301a-3p OncomiRDB external_info NA NA 23393589 RUNX3 hsa-miR-301a-3p OncomiRDB external_info NA NA 23338485 BMI1 hsa-miR-301a-3p OncomiRDB external_info NA NA 22628193 MEOX2 hsa-miR-301a-3p OncomiRDB external_info NA NA 22373864 FOXF2 hsa-miR-301a-3p OncomiRDB external_info NA NA 21393507 NKRF hsa-miR-301a-3p OncomiRDB external_info NA NA 21113131 MEOX2 hsa-miR-301a-3p OncomiRDB external_info NA NA 20470754
Predicted Targets
Count of predictions: 28309 Count of gene targets: 10303 Count of transcripts: 20474 Interacting mature miRNAs: hsa-miR-301a-3p, hsa-miR-301a-5p Prediction methods: Microtar, Miranda, Pita, Rnahybrid, Targetscan Result types: miRGate_prediction
Click on a value in the shaded box below the category label to view a detailed expression data table for that system.
alimentary part of gastrointestinal system
entire extraembryonic component
13
55
46
23
185
48
110
2
11
132
13
63
258
198
25
164
47
106
88
3
Too many to show, limit is 500. Download them if you would like to view them all.
Ensembl Acc Id:
ENST00000385261
Type:
CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38.p14 Ensembl 17 59,151,136 - 59,151,221 (-) Ensembl
RefSeq Acc Id:
NR_029842
RefSeq Status:
PROVISIONAL
Type:
NON-CODING
Position:
Human Assembly Chr Position (strand) Source GRCh38 17 59,151,136 - 59,151,221 (-) NCBI GRCh37 17 57,228,497 - 57,228,582 (-) RGD Celera 17 53,691,496 - 53,691,581 (-) RGD HuRef 17 52,589,503 - 52,589,588 (-) RGD CHM1_1 17 57,293,992 - 57,294,077 (-) NCBI T2T-CHM13v2.0 17 60,019,234 - 60,019,319 (-) NCBI
Sequence:
ACTGCTAACGAATGCTCTGACTTTATTGCACTACTGTACTTTACAGCTAGCAGTGCAATAGTATTGTCAAAGCATCTGAAAGCAGG
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