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Gene: NKRF (NFKB repressing factor) Homo sapiens
Symbol: NKRF
Name: NFKB repressing factor
Description: Exhibits DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II proximal promoter sequence-specific DNA binding activity. Involved in negative regulation of transcription, DNA-templated and positive regulation of transcription by RNA polymerase II. Localizes to the nucleolus and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ITBA4; NF-kappa-B-repressing factor; nf-kappab repressing factor; NRF; transcription factor NRF
Mus musculus (house mouse) : Nkrf (NF-kappaB repressing factor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Nkrf (NFKB repressing factor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Nkrf (NFKB repressing factor)
Pan paniscus (bonobo/pygmy chimpanzee) : NKRF (NFKB repressing factor)
Canis lupus familiaris (dog) : NKRF (NFKB repressing factor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Nkrf (NFKB repressing factor)
Sus scrofa (pig) : NKRF (NFKB repressing factor)
Chlorocebus sabaeus (African green monkey) : NKRF (NFKB repressing factor)
Heterocephalus glaber (naked mole-rat) : Nkrf (NFKB repressing factor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 EnsemblX119,588,337 - 119,606,443 (-)Ensembl
GRCh38X119,588,337 - 119,606,464 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X118,722,300 - 118,739,846 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36X118,606,334 - 118,623,841 (-)NCBINCBI36hg18NCBI36
Build 34X118,504,181 - 118,508,995NCBI
CeleraX119,177,007 - 119,194,549 (-)NCBI
Cytogenetic MapXq24NCBI
HuRefX108,215,568 - 108,232,838 (-)NCBIHuRef
CHM1_1X118,633,590 - 118,651,487 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on NKRF
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1343355
Created: 2005-03-08
Species: Homo sapiens
Last Modified: 2020-02-11
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.