GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | SERPINE1 | increases expression | ISO | Serpine1 (Rattus norvegicus) | 6480464 | CTD | Tacrolimus results in increased expression of SERPINE1 mRNA | PMID:21865292 PMID:9422427 | SERPINE1 | multiple interactions | ISO | Serpine1 (Rattus norvegicus) | 6480464 | CTD | Tacrolimus inhibits the reaction [Mercuric Chloride results in increased expression of SERPINE1 protein]; Tacrolimus inhibits the reaction [NGF protein results in increased expression of SERPINE1 mRNA]; Tacrolimus inhibits the reaction [NGF protein results in increased expression of SERPINE1 protein] | PMID:14620542 PMID:23825664 | | ||||||||||||||||||||||
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