GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | SERPINE1 | decreases expression | EXP | | 6480464 | CTD | Glucose results in decreased expression of SERPINE1 mRNA | PMID:31655124 | SERPINE1 | increases secretion | EXP | | 6480464 | CTD | Glucose results in increased secretion of SERPINE1 protein | PMID:16320596 | SERPINE1 | multiple interactions | EXP | | 6480464 | CTD | Indomethacin inhibits the reaction [Glucose results in increased secretion of SERPINE1 protein]; SOD2 protein inhibits the reaction [Glucose results in increased expression of SERPINE1 mRNA] | PMID:11050244 PMID:16320596 | SERPINE1 | increases expression | ISO | Serpine1 (Rattus norvegicus) | 6480464 | CTD | Glucose results in increased expression of SERPINE1 mRNA | PMID:12409145 | SERPINE1 | multiple interactions | ISO | Serpine1 (Rattus norvegicus) | 6480464 | CTD | 2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one inhibits the reaction [Glucose results in increased expression of SERPINE1 mRNA]; [Aldosterone co-treated with Glucose] results in increased expression of SERPINE1 mRNA; [Aldosterone co-treated with Glucose] results in increased expression of SERPINE1 protein; [Eplerenone co-treated with Enalapril] inhibits the reaction [[Aldosterone co-treated with Glucose] results in increased expression of SERPINE1 mRNA]; [Eplerenone co-treated with Enalapril] inhibits the reaction [[Aldosterone co-treated with Glucose] results in increased expression of SERPINE1 protein]; bisindolylmaleimide I inhibits the reaction [Glucose results in increased expression of SERPINE1 mRNA]; Enalapril inhibits the reaction [[Aldosterone co-treated with Glucose] results in increased expression of SERPINE1 mRNA]; Enalapril inhibits the reaction [[Aldosterone co-treated with Glucose] results in increased expression of SERPINE1 protein]; Eplerenone inhibits the reaction [[Aldosterone co-treated with Glucose] results in increased expression of SERPINE1 mRNA]; Eplerenone inhibits the reaction [[Aldosterone co-treated with Glucose] results in increased expression of SERPINE1 protein]; UCP1 protein inhibits the reaction [Glucose results in increased expression of SERPINE1 mRNA] | PMID:11050244 PMID:12409145 PMID:18682491 | | ||||||||||||||||||||||
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