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Gene: ADORA1 (adenosine A1 receptor) Homo sapiens
Symbol: ADORA1
Name: adenosine A1 receptor
Description: Predicted to have several functions, including G-protein beta/gamma-subunit complex binding activity; heterotrimeric G-protein binding activity; and neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration. Predicted to be involved in several processes, including apoptotic signaling pathway; inflammatory response; and phagocytosis. Localizes to the plasma membrane. Implicated in asthma. Biomarker of asthma and obesity.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: adenosine A1 receptor variant 1; adenosine A1 receptor variant 2; adenosine receptor A1; RDC7
Mus musculus (house mouse) : Adora1 (adenosine A1 receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Adora1 (adenosine A1 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adora1 (adenosine A1 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : ADORA1 (adenosine A1 receptor)
Canis lupus familiaris (dog) : ADORA1 (adenosine A1 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adora1 (adenosine A1 receptor)
Sus scrofa (pig) : ADORA1 (adenosine A1 receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381203,127,705 - 203,167,405 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371203,096,833 - 203,136,533 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361201,363,459 - 201,403,156 (+)NCBINCBI36hg18NCBI36
Build 341199,791,438 - 199,868,189NCBI
Celera1176,226,082 - 176,265,774 (+)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1174,262,408 - 174,301,662 (+)NCBIHuRef
CHM1_11204,519,171 - 204,558,852 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on ADORA1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730817
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.