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Gene: ADORA1 (adenosine A1 receptor) Homo sapiens
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Symbol: ADORA1
Name: adenosine A1 receptor
Description: Predicted to have several functions, including G-protein beta/gamma-subunit complex binding activity; heterotrimeric G-protein binding activity; and neurotransmitter receptor activity involved in regulation of presynaptic cytosolic calcium ion concentration. Predicted to be involved in several processes, including apoptotic signaling pathway; inflammatory response; and phagocytosis. Localizes to the plasma membrane. Implicated in asthma. Biomarker of asthma and obesity.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: adenosine A1 receptor variant 1; adenosine A1 receptor variant 2; adenosine receptor A1; RDC7
Orthologs:
Mus musculus (house mouse) : Adora1 (adenosine A1 receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Adora1 (adenosine A1 receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Adora1 (adenosine A1 receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : ADORA1 (adenosine A1 receptor)
Canis lupus familiaris (dog) : ADORA1 (adenosine A1 receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Adora1 (adenosine A1 receptor)
Sus scrofa (pig) : ADORA1 (adenosine A1 receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381203,127,705 - 203,167,405 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh371203,096,833 - 203,136,533 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 361201,363,459 - 201,403,156 (+)NCBINCBI36hg18NCBI36
Build 341199,791,438 - 199,868,189NCBI
Celera1176,226,082 - 176,265,774 (+)NCBI
Cytogenetic Map1q32.1NCBI
HuRef1174,262,408 - 174,301,662 (+)NCBIHuRef
CHM1_11204,519,171 - 204,558,852 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
 
More on ADORA1
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 730817
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2019-10-16
Status: ACTIVE



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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.