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Gene: DRD3 (dopamine receptor D3) Homo sapiens
Symbol: DRD3
Name: dopamine receptor D3
Description: Exhibits dopamine neurotransmitter receptor activity, coupled via Gi/Go and drug binding activity. Involved in several processes, including arachidonic acid secretion; behavioral response to cocaine; and dopamine receptor signaling pathway. Localizes to integral component of plasma membrane. Implicated in essential tremor; essential tremor 1; and schizophrenia. Biomarker of Alzheimer's disease and Parkinson's disease.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: D(3) dopamine receptor; D3DR; dopamine D3 receptor; essential tremor 1; ETM1; FET1; MGC149204; MGC149205
Mus musculus (house mouse) : Drd3 (dopamine receptor D3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Drd3 (dopamine receptor D3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Drd3 (dopamine receptor D3)
Pan paniscus (bonobo/pygmy chimpanzee) : DRD3 (dopamine receptor D3)
Canis lupus familiaris (dog) : DRD3 (dopamine receptor D3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Drd3 (dopamine receptor D3)
Sus scrofa (pig) : DRD3 (dopamine receptor D3)
Chlorocebus sabaeus (African green monkey) : DRD3 (dopamine receptor D3)
Heterocephalus glaber (naked mole-rat) : Drd3 (dopamine receptor D3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl3114,127,580 - 114,199,407 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl3114,128,652 - 114,199,407 (-)EnsemblGRCh38hg38GRCh38
GRCh383114,127,580 - 114,199,407 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh373113,847,499 - 113,918,254 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 363115,330,247 - 115,380,589 (-)NCBINCBI36hg18NCBI36
Celera3112,255,976 - 112,306,017 (-)NCBI
Cytogenetic Map3q13.31NCBI
HuRef3111,221,547 - 111,271,509 (-)NCBIHuRef
CHM1_13113,810,844 - 113,881,272 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DRD3
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 1605735
Created: 2007-04-28
Species: Homo sapiens
Last Modified: 2020-09-08
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.