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Gene: KCNJ11 (potassium inwardly rectifying channel subfamily J member 11) Homo sapiens
Symbol: KCNJ11
Name: potassium inwardly rectifying channel subfamily J member 11
Description: Exhibits ankyrin binding activity; ion channel binding activity; and voltage-gated potassium channel activity. Involved in several processes, including glucose metabolic process; negative regulation of insulin secretion; and response to ATP. Localizes to inward rectifying potassium channel. Implicated in familial hyperinsulinemic hypoglycemia 2 and glucose metabolism disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATP-sensitive inward rectifier potassium channel 11; beta-cell inward rectifier subunit; BIR; HHF2; IKATP; inward rectifier K(+) channel Kir6.2; inwardly rectifing potassium channel subfamily J member 11; inwardly rectifying potassium channel KIR6.2; inwardly-rectifying potassium channel subfamily J member 11; KIR6.2; MGC133230; MODY13; PHHI; PNDM2; potassium channel inwardly rectifing subfamily J member 11; potassium channel, inwardly rectifying subfamily J member 11; potassium channel, inwardly rectifying subfamily J, member 11; potassium inwardly-rectifying channel, subfamily J, member 11; potassium voltage-gated channel subfamily J member 11; TNDM3
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl1117,385,859 - 17,389,331 (-)EnsemblGRCh38hg38GRCh38
GRCh381117,385,246 - 17,389,346 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371117,406,795 - 17,410,878 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361117,363,371 - 17,366,782 (-)NCBINCBI36hg18NCBI36
Build 341117,364,788 - 17,366,737NCBI
Celera1117,536,622 - 17,540,705 (-)NCBI
Cytogenetic Map11p15.1NCBI
HuRef1117,090,617 - 17,094,700 (-)NCBIHuRef
CHM1_11117,406,598 - 17,410,681 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KCNJ11
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 69098
Created: 2001-11-08
Species: Homo sapiens
Last Modified: 2020-08-04
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.