BCL2L1 (BCL2 like 1) - Rat Genome Database

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Gene: BCL2L1 (BCL2 like 1) Homo sapiens
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Symbol: BCL2L1
Name: BCL2 like 1
RGD ID: 735516
HGNC Page HGNC
Description: Enables BH3 domain binding activity; identical protein binding activity; and protein kinase binding activity. Involved in several processes, including negative regulation of apoptotic process; negative regulation of protein localization to plasma membrane; and release of cytochrome c from mitochondria. Acts upstream of or within negative regulation of extrinsic apoptotic signaling pathway via death domain receptors; response to cytokine; and suppression by virus of host apoptotic process. Located in PUMA-BCL-xl complex; centrosome; and mitochondrial outer membrane. Part of Bcl-2 family protein complex. Implicated in breast cancer; carcinoma (multiple); leukemia (multiple); pancreatic cancer; and stomach cancer. Biomarker of several diseases, including chronic obstructive pulmonary disease; colorectal adenocarcinoma; hematologic cancer (multiple); urinary system cancer (multiple); and uterine disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: apoptosis regulator Bcl-X; bcl-2-like protein 1; Bcl-X; bcl-xL; BCL-XL/S; bcl-xS; bcl2-L-1; BCL2-like 1; BCL2L; BCLX; BCLXL; BCLXS; DKFZp781P2092; PPP1R52; protein phosphatase 1, regulatory subunit 52
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl2031,664,452 - 31,723,989 (-)EnsemblGRCh38hg38GRCh38
GRCh382031,664,452 - 31,723,963 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh372030,252,255 - 30,311,766 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 362029,715,922 - 29,774,317 (-)NCBINCBI36hg18NCBI36
Build 342029,715,923 - 29,774,317NCBI
Celera2027,008,611 - 27,067,007 (-)NCBI
Cytogenetic Map20q11.21NCBI
HuRef2027,040,965 - 27,099,720 (-)NCBIHuRef
CHM1_12030,156,171 - 30,214,537 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Experimental Pancreatitis  (ISO)
acute kidney failure  (ISO)
acute lymphoblastic leukemia  (IDA,IEP)
acute myeloid leukemia  (IEP)
adenoma  (EXP)
Alzheimer's disease  (IEP)
amyotrophic lateral sclerosis  (ISO)
amyotrophic lateral sclerosis type 1  (EXP)
B-lymphoblastic leukemia/lymphoma  (ISO)
brain ischemia  (ISO)
breast cancer  (IDA)
breast carcinoma  (IEP)
Breast Neoplasms  (IMP)
carcinoma  (EXP)
Cerebral Hemorrhage  (EXP)
cervical cancer  (IEP)
chronic myeloid leukemia  (IDA)
chronic obstructive pulmonary disease  (IEP)
colorectal adenocarcinoma  (IEP)
cryptorchidism  (EXP)
dilated cardiomyopathy  (ISO)
endometrial cancer  (IEP)
endometriosis  (ISO)
Experimental Diabetes Mellitus  (EXP,ISO)
Experimental Liver Neoplasms  (EXP,ISO)
gastric ulcer  (ISO)
Head and Neck Neoplasms  (EXP)
Hearing Loss  (EXP)
hematopoietic system disease  (IEP)
Hemorrhagic Shock  (ISO)
hepatocellular carcinoma  (EXP,ISO)
hereditary breast ovarian cancer syndrome  (IAGP)
Hypoxia-Ischemia, Brain  (ISO)
impotence  (EXP,ISO)
leiomyoma  (IEP)
liver disease  (EXP)
Liver Reperfusion Injury  (ISO)
Lung Neoplasms  (EXP)
lymphoid leukemia  (IMP)
Mammary Neoplasms, Experimental  (ISO)
melanoma  (IEP)
mental depression  (ISO)
multiple myeloma  (EXP,ISO)
myocardial infarction  (EXP,ISO)
Myocardial Reperfusion Injury  (ISO)
nephroblastoma  (IEP)
ocular hypertension  (ISO)
Ovarian Neoplasms  (IMP)
pancreatic cancer  (EXP,IMP)
plasma cell neoplasm  (ISO)
polycythemia vera  (IEP)
prostate carcinoma  (IMP)
pulmonary hypertension  (ISO)
renal cell carcinoma  (IEP)
Retina Reperfusion Injury  (ISO)
status epilepticus  (ISO)
stomach cancer  (IDA)
Stomach Neoplasms  (EXP)
Stroke  (ISO)
toxic encephalopathy  (EXP)
transitional cell carcinoma  (IMP)
type 2 diabetes mellitus  (EXP)
urinary bladder cancer  (IEP)
uterus interstitial leiomyoma  (IEP)
Viral Bronchiolitis  (IEP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-dexrazoxane  (ISO)
(+)-epicatechin-3-O-gallate  (EXP)
(+)-Tetrandrine  (EXP)
(-)-epigallocatechin 3-gallate  (EXP)
(20R)-protopanaxadiol  (EXP)
(R)-carnitine  (ISO)
(R)-lipoic acid  (ISO)
(R)-mevalonic acid  (ISO)
(R)-noradrenaline  (ISO)
(R)-Salsolinol  (ISO)
(R,R,R)-alpha-tocopherol  (ISO)
(S)-amphetamine  (EXP,ISO)
(S)-colchicine  (ISO)
(S)-naringenin  (EXP)
(S)-nicotine  (ISO)
1'-acetoxychavicol acetate  (EXP)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,3-dinitrobenzene  (EXP,ISO)
1,3-Dinitropyrene  (ISO)
1-bromopropane  (EXP,ISO)
1-nitropyrene  (ISO)
10-Hydroxycamptothecin  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
17beta-hydroxy-5alpha-androstan-3-one  (ISO)
1H-pyrazole  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,2-bis(hydroxymethyl)-1-azabicyclo[2.2.2]octan-3-one  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4-dinitrotoluene  (ISO)
2,6-dichloroindophenol  (EXP)
2-acetamidofluorene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (EXP)
2-deoxy-D-glucose  (ISO)
2-ethoxyethanol  (ISO)
2-Hydroxy-6-(8,11,14-pentadecatrienyl)benzoic acid  (EXP)
2-methoxyethanol  (ISO)
3'-amino-3'-deoxy-N(6),N(6)-dimethyladenosine  (ISO)
3,3',5-triiodo-L-thyronine  (EXP,ISO)
3,3'-diindolylmethane  (EXP)
3,4-Methylenedioxyamphetamine  (ISO)
3,4-methylenedioxymethamphetamine  (EXP,ISO)
3,7-dihydropurine-6-thione  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methyladenine  (EXP,ISO)
3-nitropropanoic acid  (ISO)
4,5,6,7-TETRABROMOBENZOTRIAZOLE  (EXP)
4-Aminobenzamide  (ISO)
4-hydroxynon-2-enal  (EXP,ISO)
4-hydroxyphenyl retinamide  (EXP,ISO)
4-nitro-m-cresol  (ISO)
4-nitrophenol  (ISO)
4-nonylphenol  (ISO)
4-vinylcyclohexene dioxide  (ISO)
5-aza-2'-deoxycytidine  (EXP)
5-azacytidine  (EXP)
5-fluorouracil  (EXP,ISO)
5-Hydroxycapric acid  (EXP)
6-chloro-2,3,4,9-tetrahydro-1H-carbazole-1-carboxamide  (ISO)
6-oxocampestanol  (EXP)
8-OH-DPAT  (ISO)
9,10-anthraquinone  (EXP)
[6]-Shogaol  (EXP)
ABT-737  (EXP,ISO)
acetochlor  (EXP)
acetylsalicylic acid  (EXP,ISO)
acrylamide  (ISO)
acrylonitrile  (EXP)
actinomycin D  (EXP)
adenosine  (EXP)
afimoxifene  (EXP)
aflatoxin B1  (EXP,ISO)
AH23848  (EXP)
aldehydo-D-glucosamine  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP,ISO)
allicin  (EXP)
alloxan  (ISO)
alpha-Zearalanol  (ISO)
aluminium atom  (EXP)
aluminium oxide  (EXP)
aluminium(0)  (EXP)
alvocidib  (EXP)
amino acid  (ISO)
ammonium chloride  (ISO)
amosite asbestos  (EXP)
amphibole asbestos  (EXP)
anthocyanin  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP,ISO)
ANTIMYCIN  (ISO)
antirheumatic drug  (EXP)
AP20187  (EXP)
apigenin  (ISO)
apocynin  (ISO)
arachidonic acid  (EXP)
arecoline  (ISO)
aripiprazole  (EXP)
arjunolic acid  (ISO)
arsane  (EXP,ISO)
arsenic atom  (EXP,ISO)
arsenous acid  (EXP,ISO)
atazanavir sulfate  (EXP)
Atranorin  (EXP,ISO)
atrazine  (EXP,ISO)
Auriculasin  (EXP)
azadirachtin A  (EXP)
azathioprine  (EXP)
azilsartan  (EXP)
benzene  (EXP,ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
Benzo[a]pyrene-7,8-diol  (EXP)
benzo[b]fluoranthene  (EXP)
benzophenanthridine  (EXP)
benzothiazoles  (EXP)
Berbamine  (EXP)
berberine  (EXP)
beta-D-glucosamine  (EXP)
bicalutamide  (EXP)
bilirubin IXalpha  (ISO)
biochanin A  (EXP)
bisphenol A  (EXP,ISO)
bortezomib  (EXP)
brassinin  (EXP)
brassinolide  (EXP)
Brusatol  (EXP)
buta-1,3-diene  (ISO)
butein  (ISO)
Butylparaben  (EXP)
C60 fullerene  (ISO)
cadmium atom  (EXP,ISO)
cadmium dichloride  (EXP,ISO)
cafestol  (EXP)
caffeine  (ISO)
Calcimycin  (ISO)
calciol  (EXP)
calcitriol  (EXP,ISO)
calyculin a  (EXP)
camalexin  (EXP)
camptothecin  (EXP,ISO)
Candesartan cilexetil  (ISO)
cannabidiol  (EXP,ISO)
cannabigerol  (ISO)
capsaicin  (EXP)
carbamazepine  (EXP)
carbon nanotube  (ISO)
carbonyl cyanide p-trifluoromethoxyphenylhydrazone  (EXP)
carboplatin  (ISO)
carmustine  (EXP,ISO)
carvedilol  (ISO)
casticin  (EXP,ISO)
cefaloridine  (ISO)
celecoxib  (EXP)
cetrorelix  (EXP)
chenodeoxycholic acid  (EXP)
chloroprene  (ISO)
chloroquine  (ISO)
chlorpromazine  (ISO)
chlorpyrifos  (ISO)
cholesterol  (EXP)
choline  (ISO)
chromium(6+)  (EXP)
chrysazin  (EXP)
chrysin  (ISO)
chrysin 5,7-dimethyl ether  (ISO)
ciguatoxin CTX1B  (ISO)
cisplatin  (EXP,ISO)
citric acid  (EXP)
Clivoline  (EXP)
clofarabine  (EXP)
clofibrate  (ISO)
clonidine  (ISO)
clonidine (amino form)  (ISO)
clonidine (imino form)  (ISO)
cobalt dichloride  (ISO)
cocaine  (ISO)
coenzyme Q10  (ISO)
copper atom  (ISO)
copper(0)  (ISO)
copper(II) chloride  (ISO)
cordycepin  (EXP)
corticosterone  (ISO)
crocidolite asbestos  (EXP,ISO)
CU-O LINKAGE  (EXP)
cucurbitacin E  (EXP)
curcumin  (EXP,ISO)
cycloheximide  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (EXP)
cylindrospermopsin  (EXP)
cypermethrin  (EXP,ISO)
cytarabine  (EXP)
D-glucose  (ISO)
dactolisib  (EXP)
daidzein  (EXP)
deguelin  (EXP)
dehydroepiandrosterone  (ISO)
dehydroepiandrosterone sulfate  (ISO)
delphinidin  (EXP)
demethoxycurcumin  (EXP)
demethoxyfumitremorgin C  (EXP)
deoxycholic acid  (EXP)
deoxynivalenol  (EXP)
depsipeptide  (EXP)
Destruxin B  (EXP)
dexamethasone  (EXP,ISO)
dexmedetomidine  (ISO)
dextromethorphan  (ISO)
diallyl trisulfide  (EXP)
diarsenic trioxide  (EXP,ISO)
diazinon  (ISO)
diazoxide  (EXP)
dibenz[a,h]anthracene  (EXP)
dibenzo[a,l]pyrene  (EXP)
diclofenac  (EXP)
dieldrin  (ISO)
diethylstilbestrol  (ISO)
dimethylarsinic acid  (EXP)
dioscin  (EXP)
diosgenin  (EXP)
dioxygen  (EXP,ISO)
dipyridamole  (EXP)
dizocilpine maleate  (ISO)
dorsomorphin  (EXP,ISO)
doxorubicin  (EXP,ISO)
doxycycline  (ISO)
elemental selenium  (EXP,ISO)
endosulfan  (ISO)
entinostat  (ISO)
erdosteine  (ISO)
Erionite  (ISO)
esculetin  (EXP)
etacrynic acid  (EXP)
ethanol  (ISO)
etoposide  (EXP)
eugenol  (ISO)
Evodiamine  (EXP)
fenofibrate  (EXP)
fenvalerate  (EXP)
finasteride  (ISO)
fisetin  (EXP)
flavonoids  (EXP,ISO)
flubendazole  (EXP)
flufenoxuron  (ISO)
fluoxetine  (ISO)
flutamide  (ISO)
folic acid  (EXP,ISO)
fucoxanthin  (EXP)
fulvestrant  (ISO)
furan  (ISO)
Fusarenone X  (ISO)
galangin  (EXP)
gamma-aminobutyric acid  (ISO)
gamma-hexachlorocyclohexane  (ISO)
gamma-tocopherol  (EXP)
Gastrodin  (ISO)
geldanamycin  (EXP)
gemcitabine  (EXP,ISO)
genistein  (EXP,ISO)
gentamycin  (EXP,ISO)
geraniol  (ISO)
Ginkgoic acid  (EXP)
glucose  (ISO)
glutathione  (EXP)
glycochenodeoxycholic acid  (EXP)
glycocholic acid  (EXP)
glycodeoxycholic acid  (EXP)
glyphosate  (EXP)
gold atom  (EXP)
gold(0)  (EXP)
gossypol  (EXP)
GW 6471  (ISO)
Gyrophoric acid  (EXP)
haloperidol  (ISO)
homoeriodictyol  (EXP)
hyaluronic acid  (EXP)
hydrogen peroxide  (EXP,ISO)
hydroxamic acid  (EXP)
hydroxyurea  (ISO)
ibrutinib  (EXP)
ibuprofen  (EXP)
idelalisib  (EXP)
Idoxifene  (ISO)
Ilimaquinone  (EXP)
indirubin-3'-monoxime  (EXP)
indole-3-methanol  (EXP)
indometacin  (EXP,ISO)
irinotecan  (EXP)
iron atom  (EXP)
iron dextran  (ISO)
iron(0)  (EXP)
isoflavones  (EXP)
isoflurane  (ISO)
isoliquiritigenin  (EXP,ISO)
isoprenaline  (EXP,ISO)
isorhamnetin  (EXP)
isotretinoin  (EXP)
kaempferol  (EXP)
kurarinol  (EXP,ISO)
L-ascorbic acid  (ISO)
L-methionine  (ISO)
lactacystin  (ISO)
lead diacetate  (EXP)
lead(0)  (ISO)
lead(2+)  (ISO)
leptomycin B  (EXP)
linalool  (EXP)
lipoic acid  (ISO)
lipopolysaccharide  (EXP,ISO)
lithium chloride  (EXP)
lithocholic acid  (ISO)
lonafarnib  (EXP)
lonidamine  (EXP)
lovastatin  (ISO)
lutein  (EXP)
luteolin  (EXP)
Luteolin 7-methyl ether  (ISO)
LY294002  (EXP,ISO)
maneb  (EXP)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
mangiferin  (EXP)
melamine  (EXP)
melatonin  (EXP,ISO)
mercaptopurine  (EXP)
mercury dichloride  (ISO)
metformin  (EXP)
methamphetamine  (EXP,ISO)
methotrexate  (EXP)
methoxychlor  (ISO)
methylmercury chloride  (ISO)
methylmercury(1+)  (ISO)
methylparaben  (EXP)
metoprolol  (ISO)
mifepristone  (ISO)
mitomycin C  (EXP)
mitoxantrone  (EXP)
mono(2-ethylhexyl) phthalate  (ISO)
monocrotaline  (ISO)
morin  (EXP)
morphine  (ISO)
morusin  (EXP)
Myrtucommulone A  (ISO)
N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine  (EXP)
N,N-dimethylformamide  (EXP,ISO)
N-(6-acetamidohexyl)acetamide  (EXP)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-[2-[4-(2-methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-Acetyl-S-(1,2-dichlorovinyl)-cysteine  (EXP)
N-acetylsphingosine  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (EXP,ISO)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP,ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
NAD zwitterion  (ISO)
NAD(+)  (ISO)
nefazodone  (EXP)
nickel dichloride  (EXP,ISO)
nickel subsulfide  (EXP)
nickel sulfate  (EXP)
niclosamide  (EXP)
nicotine  (ISO)
nitric oxide  (EXP,ISO)
nitrobenzenes  (ISO)
nitrofen  (EXP)
nitroprusside  (ISO)
Nodularin  (ISO)
Nor-9-carboxy-delta9-THC  (EXP)
NSC 23766  (ISO)
Nutlin-3  (EXP)
ochratoxin A  (EXP,ISO)
oleanolic acid  (EXP)
oltipraz  (ISO)
ouabain  (EXP)
oxaliplatin  (EXP)
oxybenzone  (ISO)
ozone  (EXP)
paclitaxel  (EXP)
paracetamol  (EXP,ISO)
paraquat  (EXP,ISO)
parathion  (ISO)
paricalcitol  (EXP)
parthenolide  (EXP)
PCB138  (ISO)
Pentoxifylline  (EXP)
pepstatin A  (EXP)
perfluorooctanoic acid  (EXP)
perindopril  (ISO)
pevonedistat  (EXP)
PHA-665752  (EXP)
phenethyl isothiocyanate  (EXP)
phenobarbital  (ISO)
phenol red  (EXP)
phenylephrine  (EXP,ISO)
phenylmercury acetate  (EXP)
phenytoin  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
phytoestrogen  (EXP)
picoxystrobin  (EXP)
picrotoxin  (ISO)
pirinixic acid  (ISO)
PK-11195  (EXP)
platycodin D  (EXP)
plumbagin  (EXP)
potassium dichromate  (ISO)
Pranoprofen  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
prochloraz  (ISO)
progesterone  (ISO)
promethazine  (EXP)
propiconazole  (ISO)
propofol  (ISO)
propylparaben  (EXP)
prostaglandin E2  (ISO)
protein kinase inhibitor  (EXP)
Psymberin  (EXP)
pterostilbene  (EXP,ISO)
purine-6-thiol  (EXP)
puromycin  (EXP)
pyrrolidine dithiocarbamate  (EXP,ISO)
quercetin  (EXP,ISO)
reactive oxygen species  (EXP)
Rebamipide  (EXP)
resveratrol  (EXP,ISO)
rifampicin  (EXP,ISO)
ritonavir  (EXP)
Ro 31-8220  (ISO)
romidepsin  (EXP)
rotenone  (EXP,ISO)
rottlerin  (EXP,ISO)
rubimaillin  (EXP)
rutin  (ISO)
Salvianolic acid A  (ISO)
salvianolic acid B  (ISO)
sarin  (EXP)
SB 203580  (ISO)
SB 431542  (EXP)
scutellarin  (ISO)
Se-methyl-L-selenocysteine  (EXP)
Se-methylselenocysteine  (EXP)
selenium atom  (EXP,ISO)
senecionine  (EXP)
sildenafil citrate  (EXP)
silicon dioxide  (ISO)
simazine  (ISO)
simvastatin  (EXP)
sirolimus  (EXP,ISO)
sodium arsenate  (EXP)
sodium arsenite  (EXP,ISO)
sodium chromate  (EXP)
sodium dichromate  (EXP,ISO)
sorafenib  (EXP)
spironolactone  (ISO)
stattic  (EXP)
staurosporine  (EXP,ISO)
stavudine  (ISO)
streptozocin  (ISO)
styrene  (EXP)
styrene oxide  (EXP)
succimer  (ISO)
succinic acid  (EXP)
sulforaphane  (EXP,ISO)
sulindac  (EXP)
sulindac sulfide  (EXP)
Sunset Yellow FCF  (EXP)
T-2 toxin  (ISO)
tacrolimus hydrate  (ISO)
tamoxifen  (EXP)
tanespimycin  (EXP)
tartrazine  (EXP)
taurine  (ISO)
tauroursodeoxycholic acid  (ISO)
Tautomycin  (EXP)
temozolomide  (EXP)
TEMPO  (ISO)
teriflunomide  (EXP)
tert-butyl hydroperoxide  (EXP,ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetramethylpyrazine  (EXP,ISO)
thalidomide  (EXP)
thapsigargin  (EXP,ISO)
thioacetamide  (ISO)
thiostrepton  (EXP)
Thiotepa  (EXP)
thymol  (ISO)
thymol sulfate(1-)  (ISO)
thymoquinone  (EXP)
tin(II) chloride (anhydrous)  (ISO)
titanium dioxide  (EXP,ISO)
tocopherol  (EXP)
Tomentosin  (EXP)
topotecan  (ISO)
tributylstannane  (ISO)
Tributyltin oxide  (EXP,ISO)
trichloroethene  (ISO)
trichostatin A  (EXP,ISO)
trimethyltin  (ISO)
Triptolide  (ISO)
triptonide  (ISO)
troglitazone  (EXP)
tunicamycin  (EXP)
Tylophorine  (EXP)
tyrphostin AG 1478  (ISO)
valproic acid  (EXP,ISO)
veliparib  (EXP)
vemurafenib  (EXP)
vinclozolin  (ISO)
vincristine  (EXP)
vitamin E  (EXP,ISO)
vorinostat  (EXP,ISO)
wortmannin  (EXP)
zerumbone  (EXP)
zinc atom  (EXP,ISO)
zinc dichloride  (EXP)
zinc protoporphyrin  (EXP,ISO)
zinc pyrithione  (EXP)
zinc sulfate  (EXP,ISO)
zinc(0)  (EXP,ISO)
zoledronic acid  (EXP)
zolmitriptan  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
aging  (ISO)
apoptotic mitochondrial changes  (TAS)
apoptotic process  (IEA,ISO)
apoptotic process in bone marrow cell  (IEA,ISO)
cell population proliferation  (IEA,ISO)
cellular response to alkaloid  (IEA,ISO)
cellular response to amino acid stimulus  (IEA,ISO)
cellular response to astaxanthin  (ISO)
cellular response to cAMP  (ISO)
cellular response to dexamethasone stimulus  (ISO)
cellular response to erythropoietin  (ISO)
cellular response to gamma radiation  (IEA,ISO)
cellular response to hypoxia  (ISO)
cellular response to interleukin-1  (ISO)
cellular response to prolactin  (ISO)
cellular response to thapsigargin  (ISO)
cellular response to tumor necrosis factor  (ISO)
cellular response to xenobiotic stimulus  (ISO)
cerebral cortex development  (ISO)
defense response to virus  (IDA)
endocytosis  (IEA)
extrinsic apoptotic signaling pathway in absence of ligand  (IBA,IEA,ISO)
fertilization  (IEA,ISO)
germ cell development  (IEA,ISO)
hepatocyte apoptotic process  (IEA,ISO)
in utero embryonic development  (IEA,ISO)
intrinsic apoptotic signaling pathway in response to DNA damage  (IBA,IEA,ISO)
male gonad development  (IEA,ISO)
mitochondrion morphogenesis  (IEA,ISO)
negative regulation of anoikis  (IMP)
negative regulation of apoptotic process  (IDA,IEA,IMP,ISO)
negative regulation of autophagy  (TAS)
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway  (IDA)
negative regulation of execution phase of apoptosis  (IDA)
negative regulation of extrinsic apoptotic signaling pathway in absence of ligand  (TAS)
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  (IDA)
negative regulation of intrinsic apoptotic signaling pathway  (IBA,IDA)
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage  (IDA)
negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway  (IDA)
negative regulation of neuron apoptotic process  (IEA,ISO)
negative regulation of protein localization to plasma membrane  (IDA)
negative regulation of release of cytochrome c from mitochondria  (IC,IDA)
neuron apoptotic process  (IEA,ISO)
ovarian follicle development  (IEA,ISO)
positive regulation of apoptotic process  (IEA,ISO)
positive regulation of ATP biosynthetic process  (ISO)
positive regulation of cell population proliferation  (IEA,ISO)
positive regulation of synaptic vesicle clustering  (ISO)
positive regulation of synaptic vesicle endocytosis  (ISO)
positive regulation of synaptic vesicle exocytosis  (ISO)
programmed cell death  (IEA)
regulation of apoptotic process  (IEA,ISO)
regulation of cellular response to stress  (IEA)
regulation of cytokinesis  (IMP)
regulation of growth  (IEA,ISO)
regulation of long-term synaptic depression  (ISO)
regulation of mitochondrial membrane permeability  (IDA)
regulation of mitochondrial membrane potential  (IDA)
release of cytochrome c from mitochondria  (IDA,IEA,ISO)
response to cycloheximide  (IEA,ISO)
response to cytokine  (IDA)
response to electrical stimulus  (ISO)
response to erythropoietin  (ISO)
response to hydrogen peroxide  (ISO)
response to hypoxia  (ISO)
response to inorganic substance  (ISO)
response to ischemia  (ISO)
response to lead ion  (ISO)
response to lipopolysaccharide  (ISO)
response to organic cyclic compound  (ISO)
response to organonitrogen compound  (ISO)
response to oxidative stress  (ISO)
response to peptide hormone  (ISO)
response to radiation  (IEA,ISO)
response to virus  (IEA,ISO)
response to xenobiotic stimulus  (ISO)
spermatogenesis  (IEA,ISO)
suppression by virus of host apoptotic process  (IDA)
synaptic vesicle recycling via endosome  (ISO)

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