HGF (hepatocyte growth factor) - Rat Genome Database

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Gene: HGF (hepatocyte growth factor) Homo sapiens
Analyze
Symbol: HGF
Name: hepatocyte growth factor
RGD ID: 70837
HGNC Page HGNC
Description: Enables chemoattractant activity and identical protein binding activity. Involved in several processes, including cellular response to hepatocyte growth factor stimulus; negative regulation of programmed cell death; and positive regulation of nitrogen compound metabolic process. Acts upstream of or within regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling. Located in membrane. Implicated in several diseases, including artery disease (multiple); autosomal recessive nonsyndromic deafness 39; eye disease (multiple); neuropathy (multiple); and scleroderma (multiple). Biomarker of several diseases, including artery disease (multiple); biliary tract disease (multiple); myositis (multiple); retinal disease (multiple); and rheumatoid arthritis (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: deafness, autosomal recessive 39; DFNB39; F-TCF; fibroblast-derived tumor cytotoxic factor; hepatocyte growth factor (hepapoietin A, scatter factor); hepatopoeitin-A; hepatopoietin-A; HGFB; HPTA; lung fibroblast-derived mitogen; SF
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl781,699,010 - 81,770,438 (-)EnsemblGRCh38hg38GRCh38
GRCh38781,699,006 - 81,770,438 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37781,328,326 - 81,399,363 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36781,169,380 - 81,237,388 (-)NCBINCBI36hg18NCBI36
Build 34781,024,867 - 81,044,103NCBI
Celera776,032,788 - 76,100,524 (-)NCBI
Cytogenetic Map7q21.11NCBI
HuRef775,935,402 - 76,003,191 (-)NCBIHuRef
CHM1_1781,261,794 - 81,329,511 (-)NCBICHM1_1
CRA_TCAGchr7v2780,663,506 - 80,731,238 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Liver Failure  (EXP)
acute myeloid leukemia  (EXP)
adult-onset Still's disease  (IEP)
angle-closure glaucoma  (IAGP)
arteriosclerosis  (IEP)
atrial fibrillation  (IEP)
autosomal recessive nonsyndromic deafness 39  (IAGP)
Barrett's esophagus  (EXP)
biliary tract benign neoplasm  (IEP)
bilirubin metabolic disorder  (IDA)
brain infarction  (ISO)
breast cancer  (ISS)
cardiomyopathy  (EXP)
carotid artery disease  (IEP)
central nervous system disease  (IEP)
cholangiocarcinoma  (IEP,ISO)
cholesteatoma  (IEP)
Choroidal Neovascularization  (ISO)
Chronic Hepatitis  (EXP)
Copper-Overload Cirrhosis  (EXP)
coronary artery disease  (IEP)
COVID-19  (HEP,IEP)
dermatomyositis  (IEP)
diabetes mellitus  (IEP)
Diabetic Nephropathies  (IMP)
diabetic neuropathy  (EXP,IMP)
diabetic retinopathy  (IEP)
epilepsy  (IAGP)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (EXP)
Experimental Liver Neoplasms  (EXP)
Experimental Melanoma  (ISO)
Experimental Neoplasms  (EXP)
Facial Nerve Injuries  (ISO)
Gallbladder Neoplasms  (IMP)
Graft vs Host Disease  (IDA)
Hearing Loss  (IAGP,IDA)
hepatocellular carcinoma  (EXP)
high grade glioma  (IEP)
hypertension  (IAGP)
interstitial lung disease  (IAGP)
inverted papilloma  (IEP)
keratoconus  (IAGP)
Lentigo  (IEP)
Limb Ischemia  (IDA)
liver cirrhosis  (EXP)
Liver Injury  (IDA)
Liver Neoplasms  (EXP)
localized scleroderma  (IDA)
malignant astrocytoma  (EXP)
malignant mesothelioma  (EXP)
meningioma  (IEP)
Metabolic Syndrome  (IDA)
myocardial infarction  (IDA,IEP)
Myocardial Ischemia  (EXP)
myopia  (IAGP)
myositis  (IEP)
Nasal Polyps  (IEP)
Neoplasm Invasiveness  (EXP)
Neoplasm Metastasis  (EXP,IDA,IEP,ISO)
neovascular inflammatory vitreoretinopathy  (IEP)
Nerve Sheath Neoplasms  (IEP)
neuroblastoma  (EXP)
obesity  (IEP)
Optic Nerve Injuries  (IDA)
Pain  (EXP)
pancreatic cancer  (IEP)
pancreatitis  (EXP)
Parkinson's disease  (EXP)
pleomorphic xanthoastrocytoma  (IAGP)
polymyositis  (IEP)
Polyomavirus Infections  (EXP)
pulmonary fibrosis  (EXP,IEP)
Reperfusion Injury  (EXP)
Retina Reperfusion Injury  (IDA,ISO)
retinal degeneration  (IDA)
Retinal Neovascularization  (ISO)
retinitis pigmentosa  (IEP)
retinopathy of prematurity  (IEP)
rheumatoid arthritis  (IEP)
Rhinosinusitis  (IAGP)
schizophrenia  (IAGP)
sciatic neuropathy  (IDA)
Skin Neoplasms  (ISO)
Spinal Cord Injuries  (IDA,ISO)
squamous cell carcinoma  (EXP)
Stroke  (ISO)
systemic scleroderma  (IDA,IEP)
thrombosis  (EXP)
tongue squamous cell carcinoma  (IEP)
vascular disease  (EXP)
visual epilepsy  (IAGP)
vitiligo  (IMP)
Wounds and Injuries  (IDA)
Wounds, Penetrating  (EXP)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-citrinin  (ISO)
(-)-epigallocatechin 3-gallate  (EXP)
(5Z,8Z,11Z,13E)-15-HETE  (EXP)
(S)-nicotine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 17-glucosiduronic acid  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-amino-2-deoxy-D-galactopyranose  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5-triiodo-L-thyronine  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (ISO)
4-phenylbutyric acid  (ISO)
5-azacytidine  (EXP)
5-fluorouracil  (EXP)
6-propyl-2-thiouracil  (ISO)
9-cis-retinoic acid  (EXP)
ABT-737  (EXP)
acetamide  (ISO)
acetic acid  (ISO)
acetylsalicylic acid  (EXP)
actinomycin D  (EXP)
all-trans-retinoic acid  (EXP)
alpha-hexachlorocyclohexane  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (EXP)
arotinoid acid  (EXP)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (EXP)
asbestos  (EXP)
aspartame  (ISO)
benazepril  (ISO)
benzalkonium chloride  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (EXP)
beraprost  (ISO)
berberine  (EXP,ISO)
bisphenol A  (ISO)
bleomycin A2  (ISO)
bromosulfophthalein  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
cannabidiol  (ISO)
captan  (ISO)
chenodeoxycholic acid  (EXP)
choline  (ISO)
ciprofibrate  (ISO)
cisplatin  (EXP)
clothianidin  (EXP)
cortisol  (EXP)
crizotinib  (EXP)
curcumin  (EXP)
cyclosporin A  (EXP)
DDT  (EXP)
deoxycholic acid  (EXP)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (EXP)
Dibromoacetonitrile  (ISO)
diethyl malate  (ISO)
dioxygen  (EXP,ISO)
disodium selenite  (EXP,ISO)
divanadium pentaoxide  (EXP)
dorsomorphin  (EXP)
doxorubicin  (EXP,ISO)
efavirenz  (EXP)
entinostat  (EXP)
ethanol  (ISO)
etodolac  (EXP)
folic acid  (ISO)
genistein  (EXP,ISO)
glutathione  (ISO)
glycochenodeoxycholic acid  (EXP)
glyphosate  (EXP)
heparin  (EXP)
hydrogen peroxide  (EXP)
indometacin  (ISO)
isoniazide  (ISO)
isotretinoin  (EXP)
kaempferol  (EXP)
L-methionine  (ISO)
lipopolysaccharide  (ISO)
melphalan  (EXP)
mercury dichloride  (ISO)
methapyrilene  (EXP)
monosodium L-glutamate  (ISO)
myricetin  (EXP)
N-acetyl-L-cysteine  (EXP)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nevirapine  (EXP)
nicotine  (ISO)
nifedipine  (EXP)
nitrofen  (ISO)
NS-398  (EXP)
ochratoxin A  (ISO)
orphenadrine  (ISO)
ouabain  (ISO)
oxilofrine  (EXP)
paracetamol  (ISO)
paraquat  (ISO)
PD173074  (EXP)
perfluorooctane-1-sulfonic acid  (ISO)
perfluorooctanoic acid  (ISO)
PHA-665752  (EXP)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP,ISO)
prostaglandin E2  (ISO)
Ptaquiloside  (ISO)
pyrithione  (ISO)
quercetin  (EXP,ISO)
quercitrin  (EXP)
raloxifene  (EXP)
reactive oxygen species  (ISO)
reserpine  (ISO)
resveratrol  (EXP,ISO)
riddelliine  (ISO)
rifampicin  (ISO)
rofecoxib  (EXP)
roxarsone  (EXP)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
salubrinal  (ISO)
SB 431542  (EXP)
Securinine  (EXP)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sorafenib  (EXP)
sphingosine 1-phosphate  (EXP)
sulfasalazine  (EXP)
sulindac sulfide  (EXP)
tacrine  (ISO)
tamoxifen  (ISO)
taurochenodeoxycholic acid  (EXP)
taurocholic acid  (ISO)
telmisartan  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thalidomide  (EXP)
thapsigargin  (ISO)
thioacetamide  (EXP,ISO)
titanium dioxide  (ISO)
trichostatin A  (EXP)
triptonide  (ISO)
tunicamycin  (ISO)
ursodeoxycholic acid  (EXP,ISO)
valproic acid  (EXP)
valsartan  (ISO)
vanadium atom  (EXP)
vanadium(0)  (EXP)
vemurafenib  (EXP)
vorinostat  (EXP)
zinc atom  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ regeneration  (IEA,ISO)
cell chemotaxis  (IDA)
cell morphogenesis  (IEA,ISO)
cellular response to hepatocyte growth factor stimulus  (IBA,IDA)
epithelial cell proliferation  (IEA,ISO)
epithelial to mesenchymal transition  (TAS)
hepatocyte growth factor receptor signaling pathway  (IBA,IDA,ISO)
hyaluronan metabolic process  (IEA)
liver development  (IEA,ISO)
mitotic cell cycle  (NAS)
myoblast proliferation  (IEA,ISO)
negative regulation of apoptotic process  (IBA,ISO)
negative regulation of autophagy  (NAS)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  (IDA)
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  (IEA,ISO)
negative regulation of hydrogen peroxide-mediated programmed cell death  (IDA)
negative regulation of inflammatory response  (IEA,ISO)
negative regulation of interleukin-6 production  (IEA,ISO)
negative regulation of peptidyl-serine phosphorylation  (IEA,ISO)
negative regulation of release of cytochrome c from mitochondria  (IDA)
positive chemotaxis  (IEA)
positive regulation of angiogenesis  (IEA,ISO)
positive regulation of cell migration  (IBA,IDA)
positive regulation of DNA biosynthetic process  (IDA)
positive regulation of interleukin-10 production  (IEA,ISO)
positive regulation of MAPK cascade  (IEA,ISO)
positive regulation of myelination  (IEA,ISO)
positive regulation of neuron projection regeneration  (IEA,ISO)
positive regulation of osteoblast differentiation  (NAS)
positive regulation of peptidyl-tyrosine phosphorylation  (IDA)
positive regulation of phosphatidylinositol 3-kinase signaling  (IDA)
positive regulation of protein phosphorylation  (IBA)
positive regulation of transcription by RNA polymerase II  (NAS)
proteolysis  (NAS)
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling  (IDA)
regulation of p38MAPK cascade  (IEA,ISO)
regulation of tau-protein kinase activity  (IEA,ISO)

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
1. Arrieta O, etal., Cancer. 2002 Jun 15;94(12):3210-8.
2. Balaban YH, etal., Indian J Gastroenterol. 2006 Jul-Aug;25(4):223-4.
3. Birchmeier C, etal., Nat Rev Mol Cell Biol. 2003 Dec;4(12):915-25.
4. Briggs MC, etal., Invest Ophthalmol Vis Sci. 2000 Sep;41(10):3085-94.
5. Castano R, etal., Otolaryngol Head Neck Surg. 2010 May;142(5):665-71.e1-2. doi: 10.1016/j.otohns.2010.01.004.
6. Colombo ES, etal., Invest Ophthalmol Vis Sci. 2007 Apr;48(4):1793-800.
7. Esaki S, etal., Gene Ther. 2011 Nov;18(11):1063-9. doi: 10.1038/gt.2011.57. Epub 2011 May 12.
8. Frost J, etal., Rheumatology (Oxford). 2012 Jun;51(6):1049-52. doi: 10.1093/rheumatology/ker367. Epub 2012 Jan 27.
9. Gentile A, etal., Cancer Metastasis Rev. 2008 Mar;27(1):85-94.
10. GOA_HUMAN data from the GO Consortium
11. Han W, etal., Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2291-9.
12. Hansel DE, etal., Am J Pathol. 2003 Jul;163(1):217-29.
13. Hashimoto N, etal., Mod Rheumatol. 2003 Jun;13(2):129-34. doi: 10.3109/s10165-002-0211-8.
14. Hasuike S, etal., J Gastroenterol Hepatol. 2005 Nov;20(11):1753-61.
15. Hernandez C, etal., Diabetes Metab. 2004 Sep;30(4):341-6.
16. Hiratsuka A, etal., J Clin Endocrinol Metab. 2005 May;90(5):2927-31. Epub 2005 Feb 15.
17. Hoshino K, etal., Arthritis Rheum. 2011 Aug;63(8):2465-72. doi: 10.1002/art.30415.
18. Hu W, etal., Exp Eye Res. 2009 Jan;88(1):79-91. doi: 10.1016/j.exer.2008.10.014. Epub 2008 Nov 1.
19. Iwasaki T, etal., Arthritis Res Ther. 2006;8(6):R161.
20. Jiang Z, etal., PLoS One. 2013 Apr 9;8(4):e60950. doi: 10.1371/journal.pone.0060950. Print 2013.
21. Kadoya A, etal., Nihon Rinsho Meneki Gakkai Kaishi. 1996 Oct;19(5):488-97.
22. Kagawa T, etal., Nephron Physiol. 2006;102(3-4):p92-102. Epub 2005 Dec 6.
23. Kato N, etal., Diabetes. 2005 Mar;54(3):846-54.
24. Katoh H, etal., Clin Exp Pharmacol Physiol. 2004 Mar;31(3):145-51.
25. Kemik O, etal., Bratisl Lek Listy. 2009;110(10):627-9.
26. Kim CH, etal., Head Neck. 2010 Dec;32(12):1655-64. doi: 10.1002/hed.21383.
27. Kitamura K, etal., J Neurosci Res. 2007 Aug 15;85(11):2332-42.
28. Kitamura K, etal., PLoS One. 2011;6(11):e27706. doi: 10.1371/journal.pone.0027706. Epub 2011 Nov 29.
29. Kovacs D, etal., Br J Dermatol. 2010 Nov;163(5):1020-7. doi: 10.1111/j.1365-2133.2010.09946.x.
30. Kunugiza Y, etal., Gene Ther. 2006 Aug;13(15):1143-52. Epub 2006 Mar 30.
31. Kurita K, etal., J Invest Dermatol. 2005 Sep;125(3):538-44.
32. Kuroiwa T, etal., J Clin Invest. 2001 Jun;107(11):1365-73.
33. Lai GH, etal., Hepatology. 2000 Jun;31(6):1257-65.
34. Lashkari K, etal., Am J Pathol. 2000 Apr;156(4):1337-44.
35. Liu QJ, etal., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2005 Nov;17(11):675-8.
36. Machida S, etal., Invest Ophthalmol Vis Sci. 2004 Nov;45(11):4174-82.
37. Miyagawa S, etal., Transplantation. 2006 Mar 27;81(6):902-7.
38. Morishita R, etal., Hypertension. 2004 Aug;44(2):203-9. Epub 2004 Jul 6.
39. Motone M, etal., Hypertens Res. 2004 Apr;27(4):247-51.
40. Naim R, etal., Acta Otolaryngol. 2004 Jun;124(5):563-8.
41. Nielsen AR, etal., J Clin Endocrinol Metab. 2008 Nov;93(11):4486-93. Epub 2008 Aug 12.
42. Nishimori H, etal., Pancreas. 2002 Apr;24(3):242-50.
43. Nishimura M, etal., J Hypertens. 1997 Oct;15(10):1137-42.
44. Noonan FP, etal., Cancer Res. 2000 Jul 15;60(14):3738-43.
45. Nowak M, etal., Endokrynol Pol. 2008 Jan-Feb;59(1):2-5.
46. OMIM Disease Annotation Pipeline
47. Online Mendelian Inheritance in Man, OMIM (TM).
48. Ono K, etal., Bone. 2006 Jul;39(1):27-34. Epub 2006 Feb 3.
49. Oshima K, etal., FASEB J. 2004 Jan;18(1):212-4. Epub 2003 Nov 20.
50. Otsuka T, etal., Cancer Res. 1998 Nov 15;58(22):5157-67.
51. Otsuka T, etal., Mol Cell Biol. 2000 Mar;20(6):2055-65.
52. Pipeline to import KEGG annotations from KEGG into RGD
53. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
54. Rao UN, etal., Hum Pathol. 1997 Sep;28(9):1066-70.
55. Rehman J, etal., J Am Coll Cardiol. 2003 Apr 16;41(8):1408-13.
56. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
57. RGD automated import pipeline for gene-chemical interactions
58. RGD automated import pipeline for human HPO-to-gene-to-disease annotations
59. Rho HS, etal., Arch Otolaryngol Head Neck Surg. 2006 Sep;132(9):985-9.
60. Saghizadeh M, etal., Invest Ophthalmol Vis Sci. 2005 Oct;46(10):3604-15.
61. Sahebjada S, etal., PLoS One. 2014 Jan 8;9(1):e84067. doi: 10.1371/journal.pone.0084067. eCollection 2014.
62. Salom D, etal., Invest Ophthalmol Vis Sci. 2010 Jun;51(6):3157-61. doi: 10.1167/iovs.09-4390. Epub 2010 Jan 6.
63. Satani K, etal., Diabet Med. 2006 Jun;23(6):617-22.
64. Schultz JM, etal., Am J Hum Genet. 2009 Jul;85(1):25-39. doi: 10.1016/j.ajhg.2009.06.003. Epub 2009 Jul 2.
65. Shibuki H, etal., Invest Ophthalmol Vis Sci. 2002 Feb;43(2):528-36.
66. Soeki T, etal., Circ J. 2002 Nov;66(11):1003-7.
67. Tanaka T, etal., Cancer Gene Ther. 2004 Jun;11(6):431-40.
68. Tonges L, etal., J Neurochem. 2011 Jun;117(5):892-903. doi: 10.1111/j.1471-4159.2011.07257.x. Epub 2011 Apr 26.
69. Tsuboi Y, etal., Acta Neurol Scand. 2002 Aug;106(2):99-103.
70. Tsuchihara T, etal., Mol Ther. 2009 Jan;17(1):42-50. doi: 10.1038/mt.2008.214. Epub 2008 Oct 21.
71. Wang P, etal., Invest Ophthalmol Vis Sci. 2009 Apr;50(4):1546-51. doi: 10.1167/iovs.08-2537. Epub 2008 Dec 5.
72. Watanabe K, etal., Cardiovasc Drugs Ther. 2001 Mar;15(2):147-53.
73. Wu MH, etal., Gene Ther. 2004 Jan;11(2):170-80.
74. Xiong Y, etal., Emerg Microbes Infect. 2020 Dec;9(1):761-770. doi: 10.1080/22221751.2020.1747363.
75. Yamaguchi Y, etal., Dig Dis Sci. 1997 Mar;42(3):522-8.
76. Yang Y, etal., J Allergy Clin Immunol. 2020 Apr 29. pii: S0091-6749(20)30576-5. doi: 10.1016/j.jaci.2020.04.027.
77. Yanovitch T, etal., Mol Vis. 2009 May 20;15:1028-35.
78. Yuan L, etal., Lin Chung Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2012 Apr;26(8):339-42.
79. Zhao MZ, etal., J Cereb Blood Flow Metab. 2006 Sep;26(9):1176-88. Epub 2006 Jan 18.
Additional References at PubMed
PMID:1280830   PMID:1321034   PMID:1328193   PMID:1334458   PMID:1386343   PMID:1482348   PMID:1531136   PMID:1535333   PMID:1655405   PMID:1720571   PMID:1824873   PMID:1826653  
PMID:1826837   PMID:1831266   PMID:1831432   PMID:1832556   PMID:1835383   PMID:1837206   PMID:1837534   PMID:1838014   PMID:1846706   PMID:2145836   PMID:2524251   PMID:2528952  
PMID:2531289   PMID:3276728   PMID:7487981   PMID:7489981   PMID:7593211   PMID:7608139   PMID:7822318   PMID:8041760   PMID:8157651   PMID:8175137   PMID:8288571   PMID:8380735  
PMID:8603858   PMID:8631970   PMID:8662798   PMID:8889548   PMID:8898205   PMID:8994391   PMID:9314600   PMID:9352114   PMID:9493272   PMID:9817840   PMID:9886295   PMID:10421795  
PMID:10725250   PMID:10848592   PMID:10871856   PMID:10962009   PMID:11342433   PMID:11597998   PMID:11781826   PMID:11799124   PMID:11821397   PMID:11830493   PMID:11836782   PMID:11839685  
PMID:11867177   PMID:11909963   PMID:11928807   PMID:11929792   PMID:11943656   PMID:11994287   PMID:11999653   PMID:12051906   PMID:12124772   PMID:12151078   PMID:12151314   PMID:12163032  
PMID:12168776   PMID:12201209   PMID:12209727   PMID:12233882   PMID:12244174   PMID:12368906   PMID:12372819   PMID:12374695   PMID:12379223   PMID:12393863   PMID:12413766   PMID:12456016  
PMID:12477932   PMID:12482615   PMID:12493396   PMID:12524084   PMID:12619035   PMID:12645668   PMID:12682635   PMID:12690205   PMID:12694198   PMID:12695295   PMID:12707786   PMID:12713878  
PMID:12732844   PMID:12757411   PMID:12792760   PMID:12812389   PMID:12817761   PMID:12821940   PMID:12837287   PMID:12837293   PMID:12847110   PMID:12853948   PMID:12865405   PMID:12875981  
PMID:12879228   PMID:12883672   PMID:12918110   PMID:12932865   PMID:14500721   PMID:14512973   PMID:14517989   PMID:14519655   PMID:14524531   PMID:14555767   PMID:14626426   PMID:14647442  
PMID:14672920   PMID:14679171   PMID:14688531   PMID:14694016   PMID:14697967   PMID:14699503   PMID:14704632   PMID:14764801   PMID:14983012   PMID:14989981   PMID:15019814   PMID:15059978  
PMID:15064106   PMID:15087580   PMID:15112327   PMID:15120936   PMID:15153617   PMID:15156160   PMID:15160305   PMID:15161915   PMID:15167892   PMID:15172968   PMID:15191880   PMID:15192042  
PMID:15203188   PMID:15226629   PMID:15229174   PMID:15239259   PMID:15240510   PMID:15241561   PMID:15250830   PMID:15287857   PMID:15292253   PMID:15334679   PMID:15359093   PMID:15474099  
PMID:15489334   PMID:15492846   PMID:15502712   PMID:15504551   PMID:15504940   PMID:15505094   PMID:15528455   PMID:15537870   PMID:15550554   PMID:15590419   PMID:15602080   PMID:15608673  
PMID:15613483   PMID:15637066   PMID:15659325   PMID:15678502   PMID:15695515   PMID:15717924   PMID:15760460   PMID:15770726   PMID:15777839   PMID:15781227   PMID:15792801   PMID:15824471  
PMID:15875782   PMID:15880501   PMID:15913806   PMID:16000876   PMID:16006475   PMID:16014626   PMID:16019534   PMID:16039997   PMID:16052207   PMID:16083876   PMID:16102116   PMID:16136515  
PMID:16144920   PMID:16216128   PMID:16278380   PMID:16279944   PMID:16303761   PMID:16338307   PMID:16403414   PMID:16469801   PMID:16498238   PMID:16505200   PMID:16537482   PMID:16554660  
PMID:16621453   PMID:16627020   PMID:16648972   PMID:16651617   PMID:16677802   PMID:16684952   PMID:16709175   PMID:16709855   PMID:16728464   PMID:16740060   PMID:16790083   PMID:16807517  
PMID:16849525   PMID:16859527   PMID:16861928   PMID:16885407   PMID:16902162   PMID:16951184   PMID:17062664   PMID:17099727   PMID:17143015   PMID:17154373   PMID:17178341   PMID:17203235  
PMID:17215249   PMID:17244893   PMID:17262819   PMID:17307814   PMID:17322284   PMID:17372204   PMID:17384084   PMID:17435158   PMID:17452892   PMID:17464544   PMID:17518673   PMID:17520376  
PMID:17593080   PMID:17597814   PMID:17599773   PMID:17625116   PMID:17625596   PMID:17626784   PMID:17702746   PMID:17804794   PMID:17872495   PMID:17876341   PMID:17901400   PMID:17907155  
PMID:17911637   PMID:17921114   PMID:17942284   PMID:17967179   PMID:17971014   PMID:17973092   PMID:17981115   PMID:17981731   PMID:17992475   PMID:18003605   PMID:18004740   PMID:18021988  
PMID:18024311   PMID:18053801   PMID:18059365   PMID:18063891   PMID:18065658   PMID:18091351   PMID:18096875   PMID:18164961   PMID:18234969   PMID:18251163   PMID:18264938   PMID:18274928  
PMID:18291418   PMID:18319552   PMID:18326526   PMID:18422749   PMID:18424072   PMID:18491380   PMID:18495663   PMID:18501120   PMID:18504429   PMID:18539758   PMID:18564920   PMID:18569024  
PMID:18585357   PMID:18593464   PMID:18628208   PMID:18691255   PMID:18774952   PMID:18787186   PMID:18789327   PMID:18812567   PMID:18813782   PMID:18844210   PMID:18956268   PMID:18973760  
PMID:18979225   PMID:18992144   PMID:19010854   PMID:19020551   PMID:19020737   PMID:19021063   PMID:19021204   PMID:19023030   PMID:19047046   PMID:19050584   PMID:19114710   PMID:19118941  
PMID:19127344   PMID:19154948   PMID:19184985   PMID:19188684   PMID:19223201   PMID:19223316   PMID:19230022   PMID:19249525   PMID:19281086   PMID:19281453   PMID:19318497   PMID:19321255  
PMID:19386985   PMID:19389925   PMID:19416273   PMID:19423096   PMID:19423540   PMID:19426716   PMID:19433454   PMID:19452723   PMID:19468262   PMID:19470725   PMID:19478261   PMID:19508152  
PMID:19515220   PMID:19521120   PMID:19525225   PMID:19526316   PMID:19533745   PMID:19542190   PMID:19553700   PMID:19563076   PMID:19615360   PMID:19625133   PMID:19628037   PMID:19661216  
PMID:19661350   PMID:19692652   PMID:19713535   PMID:19720831   PMID:19749787   PMID:19797611   PMID:19817696   PMID:19858036   PMID:19888551   PMID:19913121   PMID:19939200   PMID:19946888  
PMID:19956874   PMID:19959938   PMID:19961885   PMID:20005573   PMID:20007454   PMID:20015050   PMID:20019837   PMID:20021260   PMID:20061986   PMID:20066125   PMID:20122738   PMID:20129249  
PMID:20131016   PMID:20150826   PMID:20177149   PMID:20178463   PMID:20185166   PMID:20200025   PMID:20200161   PMID:20203323   PMID:20301607   PMID:20372801   PMID:20406964   PMID:20424473  
PMID:20438785   PMID:20483455   PMID:20519660   PMID:20533298   PMID:20534479   PMID:20558345   PMID:20568106   PMID:20580899   PMID:20584902   PMID:20624990   PMID:20628086   PMID:20655899  
PMID:20661229   PMID:20670691   PMID:20699604   PMID:20728428   PMID:20819464   PMID:20819770   PMID:20852387   PMID:20930612   PMID:20937841   PMID:20977675   PMID:20980460   PMID:21042281  
PMID:21082280   PMID:21131364   PMID:21131996   PMID:21168200   PMID:21183732   PMID:21187969   PMID:21199531   PMID:21226996   PMID:21234230   PMID:21245381   PMID:21249190   PMID:21342325  
PMID:21360495   PMID:21362320   PMID:21376809   PMID:21395178   PMID:21396819   PMID:21411099   PMID:21423210   PMID:21427651   PMID:21440951   PMID:21447729   PMID:21459729   PMID:21486864  
PMID:21561997   PMID:21572126   PMID:21643812   PMID:21658389   PMID:21703533   PMID:21723061   PMID:21750433   PMID:21777671   PMID:21779929   PMID:21782801   PMID:21784852   PMID:21796631  
PMID:21872356   PMID:21873635   PMID:21897747   PMID:21899661   PMID:21920521   PMID:21922134   PMID:21932108   PMID:22003120   PMID:22040972   PMID:22127603   PMID:22136730   PMID:22172411  
PMID:22178588   PMID:22203985   PMID:22242160   PMID:22252121   PMID:22276607   PMID:22282252   PMID:22318499   PMID:22354962   PMID:22392903   PMID:22413835   PMID:22426494   PMID:22435662  
PMID:22436613   PMID:22441736   PMID:22447520   PMID:22495710   PMID:22509107   PMID:22521434   PMID:22629140   PMID:22641068   PMID:22675553   PMID:22689693   PMID:22722904   PMID:22741575  
PMID:22744972   PMID:22749438   PMID:22763439   PMID:22771249   PMID:22788978   PMID:22802291   PMID:22843899   PMID:22848710   PMID:22850551   PMID:22854048   PMID:22859706   PMID:22876972  
PMID:22892737   PMID:22897854   PMID:22915589   PMID:22936342   PMID:22953646   PMID:22989111   PMID:22996389   PMID:23045285   PMID:23047829   PMID:23049908   PMID:23053181   PMID:23081981  
PMID:23094709   PMID:23123275   PMID:23134111   PMID:23148778   PMID:23154434   PMID:23212923   PMID:23273597   PMID:23288153   PMID:23296269   PMID:23314853   PMID:23320110   PMID:23327866  
PMID:23333382   PMID:23359207   PMID:23386689   PMID:23402812   PMID:23431957   PMID:23484149   PMID:23498810   PMID:23499762   PMID:23532910   PMID:23536720   PMID:23549785   PMID:23657814  
PMID:23667593   PMID:23701640   PMID:23737134   PMID:23749170   PMID:23773083   PMID:23882082   PMID:23898085   PMID:23911532   PMID:23924923   PMID:24018067   PMID:24023859   PMID:24025166  
PMID:24052949   PMID:24055447   PMID:24099107   PMID:24118504   PMID:24126105   PMID:24142532   PMID:24160245   PMID:24218051   PMID:24258345   PMID:24259426   PMID:24327573   PMID:24366484  
PMID:24426773   PMID:24434899   PMID:24518591   PMID:24562934   PMID:24595237   PMID:24609899   PMID:24634221   PMID:24673557   PMID:24692544   PMID:24714552   PMID:24743740   PMID:24766640  
PMID:24780821   PMID:24797571   PMID:24800946   PMID:24810547   PMID:24865428   PMID:24914205   PMID:24939420   PMID:24952592   PMID:24959005   PMID:24969882   PMID:24970050   PMID:25022754  
PMID:25029565   PMID:25057941   PMID:25064731   PMID:25101856   PMID:25162020   PMID:25184681   PMID:25198505   PMID:25212607   PMID:25241761   PMID:25244939   PMID:25338331   PMID:25351134  
PMID:25380300   PMID:25383712   PMID:25416956   PMID:25502629   PMID:25504327   PMID:25510828   PMID:25539852   PMID:25550581   PMID:25552591   PMID:25592281   PMID:25620704   PMID:25643632  
PMID:25660117   PMID:25690371   PMID:25714612   PMID:25735481   PMID:25775951   PMID:25793303   PMID:25816892   PMID:25835956   PMID:25844809   PMID:25873747   PMID:25885021   PMID:25940417  
PMID:25973105   PMID:25998175   PMID:26025956   PMID:26071245   PMID:26081218   PMID:26090463   PMID:26097553   PMID:26099202   PMID:26122834   PMID:26135603   PMID:26141862   PMID:26165838  
PMID:26181364   PMID:26186194   PMID:26254225   PMID:26282167   PMID:26310485   PMID:26327776   PMID:26332121   PMID:26335595   PMID:26381405   PMID:26400297   PMID:26518250   PMID:26527860  
PMID:26577828   PMID:26676563   PMID:26716644   PMID:26722560   PMID:26790028   PMID:26798059   PMID:26822708   PMID:26857230   PMID:26876216   PMID:26892517   PMID:26934743   PMID:26987019  
PMID:27094128   PMID:27143995   PMID:27175600   PMID:27224506   PMID:27245142   PMID:27316827   PMID:27342109   PMID:27374174   PMID:27423724   PMID:27488639   PMID:27552115   PMID:27573644  
PMID:27599544   PMID:27683052   PMID:27706656   PMID:27718226   PMID:27779808   PMID:27809600   PMID:27893712   PMID:27918718   PMID:27922668   PMID:27930387   PMID:27936146   PMID:28013036  
PMID:28076931   PMID:28077582   PMID:28151481   PMID:28205554   PMID:28314274   PMID:28341789   PMID:28358369   PMID:28364348   PMID:28423584   PMID:28447719   PMID:28475003   PMID:28476806  
PMID:28514442   PMID:28559461   PMID:28573382   PMID:28595915   PMID:28621236   PMID:28652056   PMID:28653669   PMID:28700943   PMID:28738343   PMID:28739717   PMID:28766361   PMID:28819999  
PMID:28826691   PMID:28831645   PMID:28837064   PMID:28864680   PMID:28888686   PMID:28895412   PMID:28978320   PMID:29133945   PMID:29134462   PMID:29203124   PMID:29227979   PMID:29238047  
PMID:29382231   PMID:29433373   PMID:29609131   PMID:29781036   PMID:29855336   PMID:29886319   PMID:29913557   PMID:29917165   PMID:29987050   PMID:29993037   PMID:30056064   PMID:30089804  
PMID:30108016   PMID:30108175   PMID:30136190   PMID:30158543   PMID:30186533   PMID:30191983   PMID:30309648   PMID:30400772   PMID:30404949   PMID:30514177   PMID:30569179   PMID:30592626  
PMID:30642077   PMID:30646583   PMID:30650495   PMID:30786811   PMID:30886866   PMID:30898885   PMID:30929159   PMID:30964610   PMID:31097475   PMID:31100425   PMID:31104010   PMID:31148267  
PMID:31161784   PMID:31202974   PMID:31221203   PMID:31254927   PMID:31339210   PMID:31414268   PMID:31506927   PMID:31519421   PMID:31533461   PMID:31740519   PMID:31810304   PMID:31906916  
PMID:32063608   PMID:32188473   PMID:32202143   PMID:32203220   PMID:32320127   PMID:32416690   PMID:32770199   PMID:32788873   PMID:32976979   PMID:32996054   PMID:33114380   PMID:33155201  
PMID:33212946   PMID:33218127   PMID:33233528   PMID:33451139   PMID:33648801   PMID:33670243   PMID:33760164  


Genomics

Comparative Map Data
HGF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl781,699,010 - 81,770,438 (-)EnsemblGRCh38hg38GRCh38
GRCh38781,699,006 - 81,770,438 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh37781,328,326 - 81,399,363 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36781,169,380 - 81,237,388 (-)NCBINCBI36hg18NCBI36
Build 34781,024,867 - 81,044,103NCBI
Celera776,032,788 - 76,100,524 (-)NCBI
Cytogenetic Map7q21.11NCBI
HuRef775,935,402 - 76,003,191 (-)NCBIHuRef
CHM1_1781,261,794 - 81,329,511 (-)NCBICHM1_1
CRA_TCAGchr7v2780,663,506 - 80,731,238 (-)NCBI
Hgf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39516,758,493 - 16,827,448 (+)NCBIGRCm39mm39
GRCm39 Ensembl516,758,493 - 16,825,150 (+)Ensembl
GRCm38516,553,495 - 16,619,439 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl516,553,495 - 16,620,152 (+)EnsemblGRCm38mm10GRCm38
MGSCv37516,059,368 - 16,125,257 (+)NCBIGRCm37mm9NCBIm37
MGSCv36516,065,374 - 16,131,263 (+)NCBImm8
Celera513,552,002 - 13,617,800 (+)NCBICelera
Cytogenetic Map5A3NCBI
cM Map57.07NCBI
Hgf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2418,673,736 - 18,745,582 (-)NCBImRatBN7.2
mRatBN7.2 Ensembl418,677,101 - 18,745,409 (-)Ensembl
Rnor_6.0415,435,460 - 15,505,377 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl415,433,295 - 15,505,362 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0415,408,857 - 15,478,988 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4414,864,357 - 14,932,513 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.1414,864,356 - 14,932,513 (-)NCBI
Celera414,212,976 - 14,281,167 (-)NCBICelera
Cytogenetic Map4q12NCBI
Hgf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554104,114,778 - 4,182,058 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554104,114,280 - 4,181,953 (+)NCBIChiLan1.0ChiLan1.0
HGF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1787,325,741 - 87,396,850 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl787,327,798 - 87,397,811 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0773,667,618 - 73,738,960 (-)NCBIMhudiblu_PPA_v0panPan3
HGF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11821,329,688 - 21,410,257 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1821,332,817 - 21,410,263 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1821,005,145 - 21,082,437 (-)NCBI
ROS_Cfam_1.01821,778,181 - 21,858,827 (-)NCBI
UMICH_Zoey_3.11821,417,964 - 21,495,307 (-)NCBI
UNSW_CanFamBas_1.01820,953,619 - 21,030,809 (-)NCBI
UU_Cfam_GSD_1.01821,607,548 - 21,684,870 (-)NCBI
Hgf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511863,151,279 - 63,227,083 (-)NCBI
SpeTri2.0NW_004936734354,798 - 428,356 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HGF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl998,437,087 - 98,513,156 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1998,437,771 - 98,513,573 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29108,765,929 - 108,841,386 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HGF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12167,118,785 - 67,193,506 (+)NCBI
ChlSab1.1 Ensembl2167,120,722 - 67,193,504 (+)Ensembl
Vero_WHO_p1.0NW_02366604236,762,736 - 36,834,784 (-)NCBI
Hgf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462473930,233,589 - 30,307,508 (-)NCBI

Position Markers
D7S644  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37786,285,031 - 86,285,230UniSTSGRCh37
GRCh37786,285,002 - 86,285,128UniSTSGRCh37
Build 36786,122,967 - 86,123,166RGDNCBI36
Celera780,988,976 - 80,989,102UniSTS
Celera780,989,005 - 80,989,203RGD
Cytogenetic Map7q21.1-q21.2UniSTS
Cytogenetic Map7q21.1UniSTS
HuRef780,896,264 - 80,896,461UniSTS
HuRef780,896,235 - 80,896,361UniSTS
CRA_TCAGchr7v2785,616,734 - 85,616,860UniSTS
CRA_TCAGchr7v2785,616,763 - 85,616,960UniSTS
Marshfield Genetic Map797.89RGD
Genethon Genetic Map798.3UniSTS
deCODE Assembly Map799.02UniSTS
GeneMap99-GB4 RH Map7475.84UniSTS
Whitehead-RH Map7448.8UniSTS
Whitehead-YAC Contig Map7 UniSTS
D7S3046  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37768,552,322 - 68,552,658UniSTSGRCh37
Build 36768,190,258 - 68,190,594RGDNCBI36
Celera761,933,512 - 61,933,848RGD
Cytogenetic Map7q21.1UniSTS
HuRef764,732,533 - 64,732,857UniSTS
CRA_TCAGchr7v2767,891,243 - 67,891,571UniSTS
Marshfield Genetic Map778.65UniSTS
Marshfield Genetic Map778.65RGD
RH47062  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37781,328,427 - 81,328,572UniSTSGRCh37
Build 36781,166,363 - 81,166,508RGDNCBI36
Celera776,029,771 - 76,029,916RGD
Cytogenetic Map7q21.1UniSTS
HuRef775,932,385 - 75,932,530UniSTS
CRA_TCAGchr7v2780,660,489 - 80,660,634UniSTS
GeneMap99-GB4 RH Map7458.7UniSTS
D7S804  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37781,064,729 - 81,064,830UniSTSGRCh37
GRCh37781,366,149 - 81,366,270UniSTSGRCh37
GRCh37781,343,274 - 81,343,356UniSTSGRCh37
GRCh37781,389,974 - 81,390,062UniSTSGRCh37
Build 36781,204,085 - 81,204,206RGDNCBI36
Celera776,091,046 - 76,091,134UniSTS
Celera776,044,622 - 76,044,704UniSTS
Celera776,067,221 - 76,067,342RGD
Celera775,766,127 - 75,766,228UniSTS
HuRef775,668,736 - 75,668,837UniSTS
HuRef775,969,896 - 75,970,017UniSTS
HuRef775,993,717 - 75,993,801UniSTS
HuRef775,947,236 - 75,947,318UniSTS
CRA_TCAGchr7v2780,697,935 - 80,698,056UniSTS
CRA_TCAGchr7v2780,721,760 - 80,721,848UniSTS
CRA_TCAGchr7v2780,396,832 - 80,396,933UniSTS
CRA_TCAGchr7v2780,675,336 - 80,675,418UniSTS
Marshfield Genetic Map794.87UniSTS
Marshfield Genetic Map793.63UniSTS
Marshfield Genetic Map794.4UniSTS
deCODE Assembly Map793.99UniSTS
SHGC-84463  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37781,400,699 - 81,400,901UniSTSGRCh37
Build 36781,238,635 - 81,238,837RGDNCBI36
Celera776,101,769 - 76,101,971RGD
Cytogenetic Map7q21.1UniSTS
HuRef776,004,437 - 76,004,639UniSTS
CRA_TCAGchr7v2780,732,484 - 80,732,686UniSTS
TNG Radiation Hybrid Map735188.0UniSTS
G66820  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37781,391,413 - 81,391,740UniSTSGRCh37
Build 36781,229,349 - 81,229,676RGDNCBI36
Celera776,092,485 - 76,092,812RGD
Cytogenetic Map7q21.1UniSTS
HuRef775,995,152 - 75,995,479UniSTS
CRA_TCAGchr7v2780,723,199 - 80,723,526UniSTS
SHGC-31157  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37781,384,089 - 81,384,213UniSTSGRCh37
Build 36781,222,025 - 81,222,149RGDNCBI36
Celera776,085,161 - 76,085,285RGD
Cytogenetic Map7q21.1UniSTS
HuRef775,987,832 - 75,987,956UniSTS
CRA_TCAGchr7v2780,715,875 - 80,715,999UniSTS
GeneMap99-GB4 RH Map7455.6UniSTS
Whitehead-RH Map7433.3UniSTS
NCBI RH Map7968.3UniSTS
D7S2748  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37781,331,554 - 81,331,880UniSTSGRCh37
Build 36781,169,490 - 81,169,816RGDNCBI36
Celera776,032,898 - 76,033,224RGD
Cytogenetic Map7q21.1UniSTS
HuRef775,935,512 - 75,935,838UniSTS
CRA_TCAGchr7v2780,663,616 - 80,663,942UniSTS
TNG Radiation Hybrid Map735218.0UniSTS
Stanford-G3 RH Map73825.0UniSTS
NCBI RH Map7967.8UniSTS
GeneMap99-G3 RH Map73825.0UniSTS
STS-AA015815  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7q21.1UniSTS
GeneMap99-GB4 RH Map7458.7UniSTS
D7S804  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7q21.1UniSTS
Marshfield Genetic Map794.87UniSTS
deCODE Assembly Map793.99UniSTS
D7S804  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7q21.1UniSTS
Marshfield Genetic Map794.4UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2994
Count of miRNA genes:1144
Interacting mature miRNAs:1412
Transcripts:ENST00000222390, ENST00000354224, ENST00000412881, ENST00000421558, ENST00000423064, ENST00000444829, ENST00000453018, ENST00000453411, ENST00000457544, ENST00000465234
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High 1 1
Medium 66 356 264 72 48 73 262 35 84 35 108 531 139 213 2
Low 2088 2279 1392 507 1183 352 2498 1262 1985 295 1126 870 156 1062 1588 2
Below cutoff 177 347 51 34 442 27 1526 870 1634 52 135 59 12 1 3 987

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_016274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_000601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001010931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001010932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001010933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001010934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006715956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011516115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017012097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017012098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB208900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC004960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH005424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK291674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK313694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV701693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX451992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY246560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC022308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC063485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC105797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC130284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC130286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM153501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM971901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU533235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX495370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH236949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D90334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ830861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ830862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L02931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M29145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M55379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M60718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M73239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M73240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M77227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U46010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X16323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X57574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000222390   ⟹   ENSP00000222390
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,699,010 - 81,770,047 (-)Ensembl
RefSeq Acc Id: ENST00000354224   ⟹   ENSP00000346164
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,755,121 - 81,769,971 (-)Ensembl
RefSeq Acc Id: ENST00000412881   ⟹   ENSP00000396307
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,757,246 - 81,770,398 (-)Ensembl
RefSeq Acc Id: ENST00000421558   ⟹   ENSP00000388592
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,758,704 - 81,770,438 (-)Ensembl
RefSeq Acc Id: ENST00000423064   ⟹   ENSP00000413829
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,750,889 - 81,770,136 (-)Ensembl
RefSeq Acc Id: ENST00000444829   ⟹   ENSP00000389854
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,742,691 - 81,770,048 (-)Ensembl
RefSeq Acc Id: ENST00000453018
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,756,986 - 81,762,996 (-)Ensembl
RefSeq Acc Id: ENST00000453411   ⟹   ENSP00000408270
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,742,732 - 81,770,047 (-)Ensembl
RefSeq Acc Id: ENST00000457544   ⟹   ENSP00000391238
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,702,127 - 81,770,048 (-)Ensembl
RefSeq Acc Id: ENST00000465234   ⟹   ENSP00000494355
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,751,916 - 81,770,024 (-)Ensembl
RefSeq Acc Id: ENST00000643024   ⟹   ENSP00000496217
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,755,121 - 81,769,971 (-)Ensembl
RefSeq Acc Id: NM_000601   ⟹   NP_000592
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,699,010 - 81,770,047 (-)NCBI
GRCh37781,331,444 - 81,399,452 (-)ENTREZGENE
Build 36781,169,380 - 81,237,388 (-)NCBI Archive
HuRef775,935,402 - 76,003,191 (-)ENTREZGENE
CHM1_1781,258,674 - 81,329,573 (-)NCBI
CRA_TCAGchr7v2780,663,506 - 80,731,238 (-)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001010931   ⟹   NP_001010931
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,742,691 - 81,770,047 (-)NCBI
GRCh37781,331,444 - 81,399,452 (-)ENTREZGENE
Build 36781,209,943 - 81,237,388 (-)NCBI Archive
HuRef775,935,402 - 76,003,191 (-)ENTREZGENE
CHM1_1781,302,069 - 81,329,573 (-)NCBI
CRA_TCAGchr7v2780,663,506 - 80,731,238 (-)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001010932   ⟹   NP_001010932
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,699,010 - 81,770,047 (-)NCBI
GRCh37781,331,444 - 81,399,452 (-)ENTREZGENE
Build 36781,169,380 - 81,237,388 (-)NCBI Archive
HuRef775,935,402 - 76,003,191 (-)ENTREZGENE
CHM1_1781,258,674 - 81,329,573 (-)NCBI
CRA_TCAGchr7v2780,663,506 - 80,731,238 (-)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001010933   ⟹   NP_001010933
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,742,691 - 81,770,047 (-)NCBI
GRCh37781,331,444 - 81,399,452 (-)ENTREZGENE
Build 36781,209,943 - 81,237,388 (-)NCBI Archive
HuRef775,935,402 - 76,003,191 (-)ENTREZGENE
CHM1_1781,302,069 - 81,329,573 (-)NCBI
CRA_TCAGchr7v2780,663,506 - 80,731,238 (-)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001010934   ⟹   NP_001010934
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,750,900 - 81,770,047 (-)NCBI
GRCh37781,331,444 - 81,399,452 (-)ENTREZGENE
Build 36781,218,152 - 81,237,388 (-)NCBI Archive
HuRef775,935,402 - 76,003,191 (-)ENTREZGENE
CHM1_1781,310,281 - 81,329,573 (-)NCBI
CRA_TCAGchr7v2780,663,506 - 80,731,238 (-)ENTREZGENE
Sequence:
RefSeq Acc Id: XM_006715956   ⟹   XP_006716019
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,699,006 - 81,770,438 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011516115   ⟹   XP_011514417
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,699,466 - 81,770,438 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017012097   ⟹   XP_016867586
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,742,690 - 81,770,438 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017012098   ⟹   XP_016867587
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,742,690 - 81,770,438 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_000592 (Get FASTA)   NCBI Sequence Viewer  
  NP_001010931 (Get FASTA)   NCBI Sequence Viewer  
  NP_001010932 (Get FASTA)   NCBI Sequence Viewer  
  NP_001010933 (Get FASTA)   NCBI Sequence Viewer  
  NP_001010934 (Get FASTA)   NCBI Sequence Viewer  
  XP_006716019 (Get FASTA)   NCBI Sequence Viewer  
  XP_011514417 (Get FASTA)   NCBI Sequence Viewer  
  XP_016867586 (Get FASTA)   NCBI Sequence Viewer  
  XP_016867587 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA35980 (Get FASTA)   NCBI Sequence Viewer  
  AAA52648 (Get FASTA)   NCBI Sequence Viewer  
  AAA52649 (Get FASTA)   NCBI Sequence Viewer  
  AAA52650 (Get FASTA)   NCBI Sequence Viewer  
  AAA64239 (Get FASTA)   NCBI Sequence Viewer  
  AAA64297 (Get FASTA)   NCBI Sequence Viewer  
  AAC50539 (Get FASTA)   NCBI Sequence Viewer  
  AAC71655 (Get FASTA)   NCBI Sequence Viewer  
  AAG53459 (Get FASTA)   NCBI Sequence Viewer  
  AAH22308 (Get FASTA)   NCBI Sequence Viewer  
  AAH63485 (Get FASTA)   NCBI Sequence Viewer  
  AAI05798 (Get FASTA)   NCBI Sequence Viewer  
  AAI30285 (Get FASTA)   NCBI Sequence Viewer  
  AAI30287 (Get FASTA)   NCBI Sequence Viewer  
  AAO61091 (Get FASTA)   NCBI Sequence Viewer  
  ACX45437 (Get FASTA)   NCBI Sequence Viewer  
  ACX45438 (Get FASTA)   NCBI Sequence Viewer  
  BAA14348 (Get FASTA)   NCBI Sequence Viewer  
  BAD92137 (Get FASTA)   NCBI Sequence Viewer  
  BAF84363 (Get FASTA)   NCBI Sequence Viewer  
  CAA34387 (Get FASTA)   NCBI Sequence Viewer  
  CAA40802 (Get FASTA)   NCBI Sequence Viewer  
  CAD38058 (Get FASTA)   NCBI Sequence Viewer  
  EAL24189 (Get FASTA)   NCBI Sequence Viewer  
  EAW76992 (Get FASTA)   NCBI Sequence Viewer  
  EAW76993 (Get FASTA)   NCBI Sequence Viewer  
  P14210 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001010932   ⟸   NM_001010932
- Peptide Label: isoform 3 preproprotein
- UniProtKB: P14210 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_000592   ⟸   NM_000601
- Peptide Label: isoform 1 preproprotein
- UniProtKB: P14210 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001010933   ⟸   NM_001010933
- Peptide Label: isoform 4 precursor
- UniProtKB: P14210 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001010931   ⟸   NM_001010931
- Peptide Label: isoform 2 precursor
- UniProtKB: P14210 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001010934   ⟸   NM_001010934
- Peptide Label: isoform 5 precursor
- UniProtKB: P14210 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006716019   ⟸   XM_006715956
- Peptide Label: isoform X1
- UniProtKB: P14210 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011514417   ⟸   XM_011516115
- Peptide Label: isoform X2
- UniProtKB: P14210 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016867587   ⟸   XM_017012098
- Peptide Label: isoform X4
- UniProtKB: P14210 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_016867586   ⟸   XM_017012097
- Peptide Label: isoform X3
- UniProtKB: P14210 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000413829   ⟸   ENST00000423064
RefSeq Acc Id: ENSP00000494355   ⟸   ENST00000465234
RefSeq Acc Id: ENSP00000396307   ⟸   ENST00000412881
RefSeq Acc Id: ENSP00000408270   ⟸   ENST00000453411
RefSeq Acc Id: ENSP00000391238   ⟸   ENST00000457544
RefSeq Acc Id: ENSP00000389854   ⟸   ENST00000444829
RefSeq Acc Id: ENSP00000346164   ⟸   ENST00000354224
RefSeq Acc Id: ENSP00000496217   ⟸   ENST00000643024
RefSeq Acc Id: ENSP00000222390   ⟸   ENST00000222390
RefSeq Acc Id: ENSP00000388592   ⟸   ENST00000421558
Protein Domains
Apple   Kringle   PAN   Peptidase S1

Promoters
RGD ID:6805762
Promoter ID:HG_KWN:58346
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3
Transcripts:ENST00000354224,   ENST00000394769,   NM_001010931,   NM_001010932,   NM_001010933,   OTTHUMT00000253315,   OTTHUMT00000337135,   OTTHUMT00000337170,   OTTHUMT00000337171,   OTTHUMT00000337172
Position:
Human AssemblyChrPosition (strand)Source
Build 36781,236,911 - 81,237,411 (-)MPROMDB
RGD ID:7210933
Promoter ID:EPDNEW_H11213
Type:initiation region
Name:HGF_1
Description:hepatocyte growth factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H11214  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,770,047 - 81,770,107EPDNEW
RGD ID:7210937
Promoter ID:EPDNEW_H11214
Type:initiation region
Name:HGF_2
Description:hepatocyte growth factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H11213  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,770,435 - 81,770,495EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
HGF, 3-BP DEL, 1986TGA deletion Deafness, autosomal recessive 39 [RCV000016090] Chr7:7q21.1 pathogenic
HGF, 10-BP DEL, NT482+1991 deletion Deafness, autosomal recessive 39 [RCV000016091] Chr7:7q21.1 pathogenic
NM_000601.6(HGF):c.2011-50C>A single nucleotide variant not provided [RCV001545012] Chr7:81702807 [GRCh38]
Chr7:81332123 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.495G>A (p.Ser165=) single nucleotide variant Deafness, autosomal recessive 39 [RCV000016089] Chr7:81752250 [GRCh38]
Chr7:81381566 [GRCh37]
Chr7:7q21.11
pathogenic
NM_000601.6(HGF):c.1008G>A (p.Glu336=) single nucleotide variant Deafness, autosomal recessive 39 [RCV000625228]|not provided [RCV000727188]|not specified [RCV000036550] Chr7:81729637 [GRCh38]
Chr7:81358953 [GRCh37]
Chr7:7q21.11
benign|likely benign|conflicting interpretations of pathogenicity|uncertain significance
NM_000601.6(HGF):c.1272-4A>G single nucleotide variant Deafness, autosomal recessive 39 [RCV000624946]|Nonsyndromic Hearing Loss, Mixed [RCV000391680]|not specified [RCV000036551] Chr7:81717369 [GRCh38]
Chr7:81346685 [GRCh37]
Chr7:7q21.11
benign|likely benign
NM_000601.6(HGF):c.1454T>C (p.Ile485Thr) single nucleotide variant not specified [RCV000036552] Chr7:81710234 [GRCh38]
Chr7:81339550 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.333A>G (p.Glu111=) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000327792]|not provided [RCV000711896]|not specified [RCV000036553] Chr7:81758726 [GRCh38]
Chr7:81388042 [GRCh37]
Chr7:7q21.11
benign|likely benign
NM_000601.6(HGF):c.711T>C (p.His237=) single nucleotide variant not provided [RCV000965042]|not specified [RCV000036554] Chr7:81745035 [GRCh38]
Chr7:81374351 [GRCh37]
Chr7:7q21.11
benign
NM_000601.6(HGF):c.910G>A (p.Glu304Lys) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000276154]|not specified [RCV000036555] Chr7:81729735 [GRCh38]
Chr7:81359051 [GRCh37]
Chr7:7q21.11
benign|likely benign
GRCh38/hg38 7q11.22-21.11(chr7:71225344-81735657)x1 copy number loss See cases [RCV000050709] Chr7:71225344..81735657 [GRCh38]
Chr7:70690330..81364973 [GRCh37]
Chr7:70328266..81202909 [NCBI36]
Chr7:7q11.22-21.11
pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:53985-159282531)x1 copy number loss See cases [RCV000052250] Chr7:53985..159282531 [GRCh38]
Chr7:53985..159075220 [GRCh37]
Chr7:149068..158767981 [NCBI36]
Chr7:7p22.3-q36.3
pathogenic
GRCh38/hg38 7q21.11(chr7:81674792-84509195)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052130]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052130]|See cases [RCV000052130] Chr7:81674792..84509195 [GRCh38]
Chr7:81304108..84138511 [GRCh37]
Chr7:81142044..83976447 [NCBI36]
Chr7:7q21.11
uncertain significance
GRCh38/hg38 7q11.23-21.11(chr7:73873420-83988860)x1 copy number loss See cases [RCV000054118] Chr7:73873420..83988860 [GRCh38]
Chr7:73992744..83618176 [GRCh37]
Chr7:72925686..83456112 [NCBI36]
Chr7:7q11.23-21.11
pathogenic
NM_000601.4(HGF):c.2130A>C (p.Ala710=) single nucleotide variant Malignant melanoma [RCV000067949] Chr7:81702638 [GRCh38]
Chr7:81331954 [GRCh37]
Chr7:81169890 [NCBI36]
Chr7:7q21.11
not provided
NM_000601.4(HGF):c.255-299G>C single nucleotide variant Lung cancer [RCV000106512] Chr7:81759103 [GRCh38]
Chr7:81388419 [GRCh37]
Chr7:7q21.11
uncertain significance
GRCh38/hg38 7p22.3-q36.3(chr7:54185-159282390)x1 copy number loss See cases [RCV000135401] Chr7:54185..159282390 [GRCh38]
Chr7:54185..159075079 [GRCh37]
Chr7:149268..158767840 [NCBI36]
Chr7:7p22.3-q36.3
pathogenic
NM_000601.6(HGF):c.1832G>C (p.Ser611Thr) single nucleotide variant not provided [RCV000724490]|not specified [RCV000221502] Chr7:81705679 [GRCh38]
Chr7:81334995 [GRCh37]
Chr7:7q21.11
likely benign|conflicting interpretations of pathogenicity|uncertain significance
NM_000601.6(HGF):c.1814C>T (p.Thr605Ile) single nucleotide variant not provided [RCV000724493]|not specified [RCV000218246] Chr7:81705697 [GRCh38]
Chr7:81335013 [GRCh37]
Chr7:7q21.11
likely benign|conflicting interpretations of pathogenicity|uncertain significance
GRCh38/hg38 7q11.23-21.11(chr7:74377395-82031742)x1 copy number loss See cases [RCV000142381] Chr7:74377395..82031742 [GRCh38]
Chr7:73992744..81661058 [GRCh37]
Chr7:73429661..81498994 [NCBI36]
Chr7:7q11.23-21.11
pathogenic
NM_000601.6(HGF):c.983G>T (p.Arg328Leu) single nucleotide variant Deafness, autosomal recessive 39 [RCV000477953]|not specified [RCV000150806] Chr7:81729662 [GRCh38]
Chr7:81358978 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.865+410dup duplication not specified [RCV000150807] Chr7:81742941..81742942 [GRCh38]
Chr7:81372257..81372258 [GRCh37]
Chr7:7q21.11
pathogenic|not provided
NM_000601.6(HGF):c.1041-12T>C single nucleotide variant not specified [RCV000156675] Chr7:81726029 [GRCh38]
Chr7:81355345 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.682T>G (p.Ser228Ala) single nucleotide variant not specified [RCV000150808] Chr7:81745064 [GRCh38]
Chr7:81374380 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.659G>A (p.Arg220Gln) single nucleotide variant not specified [RCV000150809] Chr7:81745087 [GRCh38]
Chr7:81374403 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.1891G>A (p.Val631Met) single nucleotide variant Deafness, autosomal recessive 39 [RCV000987900]|not specified [RCV000155127] Chr7:81705509 [GRCh38]
Chr7:81334825 [GRCh37]
Chr7:7q21.11
benign|likely benign|conflicting interpretations of pathogenicity
NM_000601.6(HGF):c.270T>C (p.Asp90=) single nucleotide variant not provided [RCV000724491]|not specified [RCV000215168] Chr7:81758789 [GRCh38]
Chr7:81388105 [GRCh37]
Chr7:7q21.11
likely benign|conflicting interpretations of pathogenicity|uncertain significance
Single allele deletion Seizures [RCV000240885] Chr7:81587754..84304468 [GRCh38]
Chr7:81217070..83933784 [GRCh37]
Chr7:7q21.11
likely pathogenic
Single allele deletion Seizures [RCV000240951] Chr7:79708363..87161076 [GRCh38]
Chr7:79337679..86790392 [GRCh37]
Chr7:7q21.11-21.12
pathogenic|likely pathogenic
NM_000601.6(HGF):c.471A>G (p.Pro157=) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000362654]|not provided [RCV001560919]|not specified [RCV000219529] Chr7:81757200 [GRCh38]
Chr7:81386516 [GRCh37]
Chr7:7q21.11
likely benign|uncertain significance
NM_000601.6(HGF):c.1540A>G (p.Arg514Gly) single nucleotide variant not specified [RCV000220633] Chr7:81710148 [GRCh38]
Chr7:81339464 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.483-20G>A single nucleotide variant not specified [RCV000242069] Chr7:81752282 [GRCh38]
Chr7:81381598 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.88+9C>T single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000321516] Chr7:81769875 [GRCh38]
Chr7:81399191 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.*396A>T single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000285931] Chr7:81702185 [GRCh38]
Chr7:81331501 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.-40A>T single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000286375] Chr7:81770011 [GRCh38]
Chr7:81399327 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.1715A>G (p.Tyr572Cys) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000355882] Chr7:81706329 [GRCh38]
Chr7:81335645 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.5(HGF):c.-94G>T single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000399680] Chr7:81770065 [GRCh38]
Chr7:81399381 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.4T>C (p.Trp2Arg) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000378490] Chr7:81769968 [GRCh38]
Chr7:81399284 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.1041-6C>T single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000311558] Chr7:81726023 [GRCh38]
Chr7:81355339 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.800C>T (p.Pro267Leu) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000333616] Chr7:81743418 [GRCh38]
Chr7:81372734 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.-44A>G single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000334350] Chr7:81770015 [GRCh38]
Chr7:81399331 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.921A>C (p.Gln307His) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000368393] Chr7:81729724 [GRCh38]
Chr7:81359040 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.1765G>A (p.Val589Ile) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000298690]|not provided [RCV000883919]|not specified [RCV000615950] Chr7:81705746 [GRCh38]
Chr7:81335062 [GRCh37]
Chr7:7q21.11
benign|likely benign|uncertain significance
NM_000601.6(HGF):c.1904A>G (p.Tyr635Cys) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000391658] Chr7:81705496 [GRCh38]
Chr7:81334812 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.137C>T (p.Ala46Val) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000283216]|not provided [RCV000973134]|not specified [RCV000608266] Chr7:81762824 [GRCh38]
Chr7:81392140 [GRCh37]
Chr7:7q21.11
likely benign|uncertain significance
NM_000601.6(HGF):c.2019T>C (p.Tyr673=) single nucleotide variant not provided [RCV000303305] Chr7:81702749 [GRCh38]
Chr7:81332065 [GRCh37]
Chr7:7q21.11
conflicting interpretations of pathogenicity|uncertain significance
NM_000601.6(HGF):c.438C>A (p.Gly146=) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000270369] Chr7:81757233 [GRCh38]
Chr7:81386549 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.1445-152G>A single nucleotide variant not provided [RCV001567077] Chr7:81710395 [GRCh38]
Chr7:81339711 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.147C>G (p.Thr49=) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000384633] Chr7:81762814 [GRCh38]
Chr7:81392130 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.*467A>G single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000374709] Chr7:81702114 [GRCh38]
Chr7:81331430 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.*101A>G single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000343182] Chr7:81702480 [GRCh38]
Chr7:81331796 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.717A>G (p.Thr239=) single nucleotide variant not provided [RCV000733016] Chr7:81745029 [GRCh38]
Chr7:81374345 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.1675G>A (p.Glu559Lys) single nucleotide variant not provided [RCV000728416] Chr7:81706369 [GRCh38]
Chr7:81335685 [GRCh37]
Chr7:7q21.11
uncertain significance
TMEM106B-BRAF fusion deletion Pleomorphic xanthoastrocytoma [RCV000454357] Chr7:12258147..140494267 [GRCh37]
Chr7:7p21.3-q34
pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43360-159119707)x1 copy number loss See cases [RCV000446044] Chr7:43360..159119707 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
GRCh37/hg19 7q21.11(chr7:81355319-81663832)x3 copy number gain See cases [RCV000447818] Chr7:81355319..81663832 [GRCh37]
Chr7:7q21.11
likely benign
NC_000007.14:g.(?_81485635)_(84094822_?)del deletion Schizophrenia [RCV000416754] Chr7:81485635..84094822 [GRCh38]
Chr7:81114951..83724138 [GRCh37]
Chr7:80952887..83562074 [NCBI36]
Chr7:7q21.11
likely pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707) copy number gain See cases [RCV000510686] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
GRCh37/hg19 7q21.11(chr7:80348675-83666606)x1 copy number loss See cases [RCV000511923] Chr7:80348675..83666606 [GRCh37]
Chr7:7q21.11
likely pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707)x3 copy number gain See cases [RCV000511549] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
NM_000601.6(HGF):c.258T>C (p.Ala86=) single nucleotide variant not provided [RCV000892097]|not specified [RCV000609442] Chr7:81758801 [GRCh38]
Chr7:81388117 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1934A>G (p.His645Arg) single nucleotide variant not specified [RCV000609946] Chr7:81705466 [GRCh38]
Chr7:81334782 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.1406-3C>T single nucleotide variant not specified [RCV000615891] Chr7:81711522 [GRCh38]
Chr7:81340838 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.865+11G>A single nucleotide variant not specified [RCV000616912] Chr7:81743342 [GRCh38]
Chr7:81372658 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.146C>A (p.Thr49Asn) single nucleotide variant not specified [RCV000608473] Chr7:81762815 [GRCh38]
Chr7:81392131 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.1818T>C (p.Ile606=) single nucleotide variant not specified [RCV000614331] Chr7:81705693 [GRCh38]
Chr7:81335009 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.2179C>T (p.Gln727Ter) single nucleotide variant not specified [RCV000601187] Chr7:81702589 [GRCh38]
Chr7:81331905 [GRCh37]
Chr7:7q21.11
likely benign|uncertain significance
Single allele deletion not provided [RCV000677988] Chr7:73591993..93683437 [GRCh37]
Chr7:7q11.23-21.3
uncertain significance
NM_000601.6(HGF):c.482+286_482+287insCCCTTT insertion not provided [RCV001566402] Chr7:81756902..81756903 [GRCh38]
Chr7:81386218..81386219 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.865+555C>A single nucleotide variant not provided [RCV001565564] Chr7:81742798 [GRCh38]
Chr7:81372114 [GRCh37]
Chr7:7q21.11
likely benign
NC_000007.13:g.(20954043_21001537)_(114528369_114556605)inv inversion Speech-language disorder 1 [RCV000234948] Chr7:21001537..114528369 [GRCh37]
Chr7:7p15.3-q31.1
pathogenic
NM_000601.6(HGF):c.483-153A>G single nucleotide variant not provided [RCV001539452] Chr7:81752415 [GRCh38]
Chr7:81381731 [GRCh37]
Chr7:7q21.11
benign
GRCh37/hg19 7p22.3-q36.3(chr7:44935-159126310)x3 copy number gain not provided [RCV000746280] Chr7:44935..159126310 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
NC_000007.14:g.(?_81478831)_(84097791_?)del deletion Schizophrenia [RCV000754335] Chr7:81478831..84097791 [GRCh38]
Chr7:7q21.11
likely pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:10704-159122532)x3 copy number gain not provided [RCV000746278] Chr7:10704..159122532 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
GRCh37/hg19 7q21.11(chr7:81026186-81466742)x3 copy number gain not provided [RCV000746846] Chr7:81026186..81466742 [GRCh37]
Chr7:7q21.11
likely benign
GRCh37/hg19 7q21.11(chr7:81206169-81418596)x3 copy number gain not provided [RCV000746847] Chr7:81206169..81418596 [GRCh37]
Chr7:7q21.11
benign
NM_000601.6(HGF):c.2011-160A>G single nucleotide variant not provided [RCV001571670] Chr7:81702917 [GRCh38]
Chr7:81332233 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.368-46A>G single nucleotide variant not provided [RCV001565568] Chr7:81757349 [GRCh38]
Chr7:81386665 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.482+22G>A single nucleotide variant not provided [RCV001551686] Chr7:81757167 [GRCh38]
Chr7:81386483 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1168+231C>A single nucleotide variant not provided [RCV001566673] Chr7:81725659 [GRCh38]
Chr7:81354975 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1662C>T (p.His554=) single nucleotide variant not provided [RCV000925507] Chr7:81706382 [GRCh38]
Chr7:81335698 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.762C>T (p.Gly254=) single nucleotide variant not provided [RCV000981529] Chr7:81743456 [GRCh38]
Chr7:81372772 [GRCh37]
Chr7:7q21.11
benign
NM_000601.6(HGF):c.1865-4C>T single nucleotide variant not provided [RCV000949312] Chr7:81705539 [GRCh38]
Chr7:81334855 [GRCh37]
Chr7:7q21.11
likely benign
GRCh37/hg19 7p22.3-q36.3(chr7:10365-159119707)x3 copy number gain not provided [RCV000848126] Chr7:10365..159119707 [GRCh37]
Chr7:7p22.3-q36.3
pathogenic
NM_000601.6(HGF):c.594C>T (p.Tyr198=) single nucleotide variant not provided [RCV000922288] Chr7:81752151 [GRCh38]
Chr7:81381467 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.2016T>C (p.Asp672=) single nucleotide variant not provided [RCV000926596] Chr7:81702752 [GRCh38]
Chr7:81332068 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1627G>T (p.Asp543Tyr) single nucleotide variant not provided [RCV000841416] Chr7:81706417 [GRCh38]
Chr7:81335733 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1942G>A (p.Gly648Arg) single nucleotide variant not specified [RCV000825934] Chr7:81705458 [GRCh38]
Chr7:81334774 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.2011-3dup duplication not specified [RCV000825936] Chr7:81702759..81702760 [GRCh38]
Chr7:81332075..81332076 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.1616+71G>T single nucleotide variant not provided [RCV000842921] Chr7:81707219 [GRCh38]
Chr7:81336535 [GRCh37]
Chr7:7q21.11
benign
NM_000601.6(HGF):c.885C>T (p.Asp295=) single nucleotide variant not provided [RCV000960894]|not specified [RCV001195193] Chr7:81729760 [GRCh38]
Chr7:81359076 [GRCh37]
Chr7:7q21.11
likely benign
GRCh37/hg19 7q21.11(chr7:81075835-81387108)x3 copy number gain not provided [RCV000846300] Chr7:81075835..81387108 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.89-233A>G single nucleotide variant not provided [RCV001544909] Chr7:81763105 [GRCh38]
Chr7:81392421 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1617-175T>G single nucleotide variant not provided [RCV001571511] Chr7:81706602 [GRCh38]
Chr7:81335918 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.626-318C>T single nucleotide variant not provided [RCV001560537] Chr7:81745438 [GRCh38]
Chr7:81374754 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1541+221T>C single nucleotide variant not provided [RCV001555461] Chr7:81709926 [GRCh38]
Chr7:81339242 [GRCh37]
Chr7:7q21.11
likely benign
Single allele single nucleotide variant not provided [RCV001555801] Chr7:81770271 [GRCh38]
Chr7:81399587 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1041-339A>G single nucleotide variant not provided [RCV001561330] Chr7:81726356 [GRCh38]
Chr7:81355672 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1271+209T>C single nucleotide variant not provided [RCV001562043] Chr7:81720536 [GRCh38]
Chr7:81349852 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1271+190A>T single nucleotide variant not provided [RCV001564622] Chr7:81720555 [GRCh38]
Chr7:81349871 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1616+22T>C single nucleotide variant not provided [RCV001571581] Chr7:81707268 [GRCh38]
Chr7:81336584 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1041-319T>C single nucleotide variant not provided [RCV001557956] Chr7:81726336 [GRCh38]
Chr7:81355652 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1758-119_1758-118del deletion not provided [RCV001568012] Chr7:81705871..81705872 [GRCh38]
Chr7:81335187..81335188 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1272-120A>G single nucleotide variant not provided [RCV001558458] Chr7:81717485 [GRCh38]
Chr7:81346801 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.746+27A>G single nucleotide variant not provided [RCV001558883] Chr7:81744973 [GRCh38]
Chr7:81374289 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.254+27A>G single nucleotide variant not provided [RCV001547223] Chr7:81762680 [GRCh38]
Chr7:81391996 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1865-12_1865-6del deletion not provided [RCV000949313] Chr7:81705541..81705547 [GRCh38]
Chr7:81334857..81334863 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1704C>T (p.Ser568=) single nucleotide variant not provided [RCV000925652] Chr7:81706340 [GRCh38]
Chr7:81335656 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1542-214T>G single nucleotide variant not provided [RCV001556913] Chr7:81707578 [GRCh38]
Chr7:81336894 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.865+73A>G single nucleotide variant not provided [RCV001558069] Chr7:81743280 [GRCh38]
Chr7:81372596 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.747-214T>C single nucleotide variant not provided [RCV001558073] Chr7:81743685 [GRCh38]
Chr7:81373001 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1617-154G>C single nucleotide variant not provided [RCV001553340] Chr7:81706581 [GRCh38]
Chr7:81335897 [GRCh37]
Chr7:7q21.11
likely benign
Single allele single nucleotide variant not provided [RCV001553506] Chr7:81770189 [GRCh38]
Chr7:81399505 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1617-34T>C single nucleotide variant not provided [RCV001576043] Chr7:81706461 [GRCh38]
Chr7:81335777 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.1617-289A>C single nucleotide variant not provided [RCV001547838] Chr7:81706716 [GRCh38]
Chr7:81336032 [GRCh37]
Chr7:7q21.11
likely benign
NM_000601.6(HGF):c.754G>C (p.Asp252His) single nucleotide variant not specified [RCV001195382] Chr7:81743464 [GRCh38]
Chr7:81372780 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.1295C>T (p.Ala432Val) single nucleotide variant not provided [RCV001289448] Chr7:81717342 [GRCh38]
Chr7:81346658 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.229A>G (p.Asn77Asp) single nucleotide variant not provided [RCV001355257] Chr7:81762732 [GRCh38]
Chr7:81392048 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.2183C>A (p.Ser728Ter) single nucleotide variant Hearing impairment [RCV001375429] Chr7:81702585 [GRCh38]
Chr7:81331901 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.1343A>G (p.His448Arg) single nucleotide variant not specified [RCV001449763] Chr7:81717294 [GRCh38]
Chr7:81346610 [GRCh37]
Chr7:7q21.11
uncertain significance
NM_000601.6(HGF):c.1541+256G>A single nucleotide variant not provided [RCV001534080] Chr7:81709891 [GRCh38]
Chr7:81339207 [GRCh37]
Chr7:7q21.11
benign

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:4893 AgrOrtholog
COSMIC HGF COSMIC
Ensembl Genes ENSG00000019991 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000222390 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000346164 UniProtKB/TrEMBL
  ENSP00000388592 UniProtKB/TrEMBL
  ENSP00000389854 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000391238 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000396307 UniProtKB/TrEMBL
  ENSP00000408270 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000413829 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000494355 UniProtKB/TrEMBL
  ENSP00000496217 UniProtKB/TrEMBL
Ensembl Transcript ENST00000222390 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000354224 UniProtKB/TrEMBL
  ENST00000412881 UniProtKB/TrEMBL
  ENST00000421558 UniProtKB/TrEMBL
  ENST00000423064 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000444829 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000453411 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000457544 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000465234 UniProtKB/TrEMBL
  ENST00000643024 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/Swiss-Prot
  2.40.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000019991 GTEx
HGNC ID HGNC:4893 ENTREZGENE
Human Proteome Map HGF Human Proteome Map
InterPro Hepatocyte_GF UniProtKB/Swiss-Prot
  HGF-like UniProtKB/Swiss-Prot
  Kringle UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kringle-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kringle_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kringle_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pan_app UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S1_PA UniProtKB/Swiss-Prot
  Peptidase_S1_PA_chymotrypsin UniProtKB/Swiss-Prot
  Peptidase_S1A UniProtKB/Swiss-Prot
  Trypsin_dom UniProtKB/Swiss-Prot
KEGG Report hsa:3082 UniProtKB/Swiss-Prot
NCBI Gene 3082 ENTREZGENE
OMIM 142409 OMIM
  608265 OMIM
Pfam Kringle UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Trypsin UniProtKB/Swiss-Prot
PharmGKB PA29269 PharmGKB
PIRSF Hepatocyte_GF UniProtKB/Swiss-Prot
  HGF_MST1 UniProtKB/Swiss-Prot
PRINTS CHYMOTRYPSIN UniProtKB/Swiss-Prot
PROSITE KRINGLE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KRINGLE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRYPSIN_DOM UniProtKB/Swiss-Prot
SMART PAN_AP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00130 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tryp_SPc UniProtKB/Swiss-Prot
Superfamily-SCOP SSF50494 UniProtKB/Swiss-Prot
  SSF57440 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2R8YEI1_HUMAN UniProtKB/TrEMBL
  C9JDP4_HUMAN UniProtKB/TrEMBL
  C9JS80_HUMAN UniProtKB/TrEMBL
  C9WSJ3_HUMAN UniProtKB/TrEMBL
  C9WSJ4_HUMAN UniProtKB/TrEMBL
  HGF_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
UniProt Secondary A1L3U6 UniProtKB/Swiss-Prot
  Q02935 UniProtKB/Swiss-Prot
  Q13494 UniProtKB/Swiss-Prot
  Q14519 UniProtKB/Swiss-Prot
  Q3KRB2 UniProtKB/Swiss-Prot
  Q8TCE2 UniProtKB/Swiss-Prot
  Q9BYL9 UniProtKB/Swiss-Prot
  Q9BYM0 UniProtKB/Swiss-Prot
  Q9UDU6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-05 HGF  hepatocyte growth factor  DFNB39  deafness, autosomal recessive 39  Data Merged 737654 PROVISIONAL
2016-02-10 HGF  hepatocyte growth factor    hepatocyte growth factor (hepapoietin A; scatter factor)  Symbol and/or name change 5135510 APPROVED