HGF (hepatocyte growth factor) - Rat Genome Database

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Gene: HGF (hepatocyte growth factor) Homo sapiens
Analyze
Symbol: HGF
Name: hepatocyte growth factor
RGD ID: 70837
HGNC Page HGNC:4893
Description: Enables chemoattractant activity and identical protein binding activity. Involved in several processes, including cellular response to hepatocyte growth factor stimulus; negative regulation of programmed cell death; and positive regulation of nitrogen compound metabolic process. Acts upstream of or within regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling. Located in membrane. Implicated in several diseases, including artery disease (multiple); autosomal recessive nonsyndromic deafness 39; eye disease (multiple); neuropathy (multiple); and scleroderma (multiple). Biomarker of several diseases, including artery disease (multiple); biliary tract disease (multiple); myositis (multiple); retinal disease (multiple); and rheumatoid arthritis (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: deafness, autosomal recessive 39; DFNB39; F-TCF; fibroblast-derived tumor cytotoxic factor; hepatocyte growth factor (hepapoietin A, scatter factor); hepatopoeitin-A; hepatopoietin-A; HGFB; HPTA; lung fibroblast-derived mitogen; SF
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38781,699,010 - 81,770,047 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl781,699,010 - 81,770,438 (-)EnsemblGRCh38hg38GRCh38
GRCh37781,328,326 - 81,399,363 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36781,169,380 - 81,237,388 (-)NCBINCBI36Build 36hg18NCBI36
Build 34781,024,867 - 81,044,103NCBI
Celera776,032,788 - 76,100,524 (-)NCBICelera
Cytogenetic Map7q21.11NCBI
HuRef775,935,402 - 76,003,191 (-)NCBIHuRef
CHM1_1781,261,794 - 81,329,511 (-)NCBICHM1_1
T2T-CHM13v2.0782,951,060 - 83,022,099 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2780,663,506 - 80,731,238 (-)NCBI
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View
Acute Liver Failure  (EXP)
acute myeloid leukemia  (EXP)
adult-onset Still's disease  (IEP)
angle-closure glaucoma  (IAGP)
arteriosclerosis  (IEP)
atrial fibrillation  (IEP)
autism spectrum disorder  (EXP)
autosomal recessive nonsyndromic deafness 39  (IAGP)
Barrett's esophagus  (EXP)
biliary tract benign neoplasm  (IEP)
bilirubin metabolic disorder  (IDA)
brain infarction  (ISO)
breast cancer  (ISS)
cardiomyopathy  (EXP)
carotid artery disease  (IEP)
central nervous system disease  (IEP)
CHARGE syndrome  (IAGP)
cholangiocarcinoma  (IEP,ISO)
cholesteatoma  (IEP)
Choroidal Neovascularization  (ISO)
Chronic Hepatitis  (EXP)
Copper-Overload Cirrhosis  (EXP)
coronary artery disease  (IEP)
COVID-19  (HEP,IEP)
dermatomyositis  (IEP)
diabetes mellitus  (IEP)
Diabetic Nephropathies  (IMP)
diabetic neuropathy  (EXP,IMP)
diabetic retinopathy  (IEP)
epilepsy  (IAGP)
Experimental Diabetes Mellitus  (ISO)
Experimental Liver Cirrhosis  (EXP)
Experimental Liver Neoplasms  (EXP)
Experimental Melanoma  (ISO)
Experimental Neoplasms  (EXP)
Facial Nerve Injuries  (ISO)
Gallbladder Neoplasms  (IMP)
genetic disease  (IAGP)
graft-versus-host disease  (IDA)
Hearing Loss  (IAGP,IDA)
hepatocellular carcinoma  (EXP)
high grade glioma  (IEP)
hypertension  (IAGP)
interstitial lung disease  (IAGP)
inverted papilloma  (IEP)
keratoconus  (IAGP)
Lentigo  (IEP)
limb ischemia  (IDA)
liver cirrhosis  (EXP)
Liver Injury  (IDA)
Liver Neoplasms  (EXP)
localized scleroderma  (IDA)
malignant astrocytoma  (EXP)
malignant mesothelioma  (EXP)
meningioma  (IEP)
Metabolic Syndrome  (IDA)
myocardial infarction  (IDA,IEP)
Myocardial Ischemia  (EXP)
myopia  (IAGP)
myositis  (IEP)
Nasal Polyps  (IEP)
Neoplasm Invasiveness  (EXP)
Neoplasm Metastasis  (EXP,IDA,IEP,ISO)
neovascular inflammatory vitreoretinopathy  (IEP)
Nerve Sheath Neoplasms  (IEP)
neuroblastoma  (EXP)
obesity  (IEP)
Optic Nerve Injuries  (IDA)
Pain  (EXP)
pancreatic cancer  (IEP)
pancreatitis  (EXP)
Parkinson's disease  (EXP)
Penetrating Wounds  (EXP)
pleomorphic xanthoastrocytoma  (IAGP)
polymyositis  (IEP)
Polyomavirus Infections  (EXP)
pulmonary fibrosis  (EXP,IEP)
Reperfusion Injury  (EXP)
Retina Reperfusion Injury  (IDA,ISO)
retinal degeneration  (IDA)
Retinal Neovascularization  (ISO)
retinitis pigmentosa  (IEP)
retinopathy of prematurity  (IEP)
rheumatoid arthritis  (IEP)
Rhinosinusitis  (IAGP)
schizophrenia  (IAGP)
sciatic neuropathy  (IDA)
Skin Neoplasms  (ISO)
Spinal Cord Injuries  (IDA,ISO)
squamous cell carcinoma  (EXP)
Stroke  (ISO)
systemic scleroderma  (IDA,IEP)
thrombosis  (EXP)
tongue squamous cell carcinoma  (IEP)
vascular disease  (EXP)
vitiligo  (IMP)
Wounds and Injuries  (IDA)

Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(-)-citrinin  (ISO)
(-)-epigallocatechin 3-gallate  (EXP)
(5Z,8Z,11Z,13E)-15-HETE  (EXP)
(S)-nicotine  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 17-glucosiduronic acid  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-tribromophenol  (EXP)
2-amino-2-deoxy-D-galactopyranose  (ISO)
3,3',4,4',5-pentachlorobiphenyl  (EXP)
3,3',5-triiodo-L-thyronine  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (ISO)
3-methylcholanthrene  (ISO)
3H-1,2-dithiole-3-thione  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-hydroxynon-2-enal  (EXP)
4-hydroxyphenyl retinamide  (ISO)
4-phenylbutyric acid  (ISO)
5-azacytidine  (EXP)
5-fluorouracil  (EXP)
6-propyl-2-thiouracil  (ISO)
9-cis-retinoic acid  (EXP)
ABT-737  (EXP)
acetamide  (ISO)
acetic acid  (ISO)
acetylsalicylic acid  (EXP)
actinomycin D  (EXP)
all-trans-retinoic acid  (EXP)
alpha-hexachlorocyclohexane  (ISO)
ammonium chloride  (ISO)
antirheumatic drug  (EXP)
arotinoid acid  (EXP)
arsane  (EXP)
arsenic atom  (EXP)
arsenous acid  (EXP)
asbestos  (EXP)
aspartame  (ISO)
atazanavir sulfate  (EXP)
benazepril  (ISO)
benzalkonium chloride  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[e]pyrene  (EXP)
beraprost  (ISO)
berberine  (EXP,ISO)
bisphenol A  (EXP,ISO)
bleomycin A2  (ISO)
bromosulfophthalein  (ISO)
cadmium atom  (ISO)
cadmium dichloride  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
cannabidiol  (ISO)
captan  (ISO)
chenodeoxycholic acid  (EXP)
CHIR 99021  (EXP)
choline  (ISO)
ciprofibrate  (ISO)
cisplatin  (EXP)
clothianidin  (EXP)
cortisol  (EXP)
crizotinib  (EXP)
curcumin  (EXP)
cyclosporin A  (EXP)
DDT  (EXP)
deoxycholic acid  (EXP)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (EXP)
Dibromoacetonitrile  (ISO)
diethyl malate  (ISO)
dioxygen  (EXP,ISO)
disodium selenite  (EXP,ISO)
divanadium pentaoxide  (EXP)
dorsomorphin  (EXP)
doxorubicin  (EXP,ISO)
efavirenz  (EXP)
entinostat  (EXP)
ethanol  (ISO)
etodolac  (EXP)
folic acid  (ISO)
genistein  (EXP,ISO)
glutathione  (ISO)
glycochenodeoxycholic acid  (EXP)
glycocholic acid  (EXP)
glycodeoxycholic acid  (EXP)
glyphosate  (EXP)
heparin  (EXP)
hydrogen peroxide  (EXP)
indometacin  (ISO)
isoniazide  (ISO)
isotretinoin  (EXP)
kaempferol  (EXP)
L-ascorbic acid  (EXP)
L-methionine  (ISO)
lipopolysaccharide  (EXP,ISO)
melphalan  (EXP)
mercury dichloride  (ISO)
methapyrilene  (EXP)
monosodium L-glutamate  (ISO)
myricetin  (EXP)
N-acetyl-L-cysteine  (EXP)
N-butyl-N-(4-hydroxybutyl)nitrosamine  (ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
nefazodone  (EXP)
nevirapine  (EXP)
nicotine  (ISO)
nifedipine  (EXP)
nitrofen  (ISO)
NS-398  (EXP)
NSC 23766  (EXP)
ochratoxin A  (ISO)
orphenadrine  (ISO)
ouabain  (ISO)
oxilofrine  (EXP)
paracetamol  (EXP,ISO)
paraquat  (ISO)
PD173074  (EXP)
perfluorodecanoic acid  (EXP)
perfluorohexanesulfonic acid  (EXP)
perfluorononanoic acid  (EXP)
perfluorooctane-1-sulfonic acid  (EXP,ISO)
perfluorooctanoic acid  (EXP,ISO)
perfluoroundecanoic acid  (EXP)
PHA-665752  (EXP)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
pirinixic acid  (ISO)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (EXP,ISO)
prostaglandin E2  (ISO)
Ptaquiloside  (ISO)
pyrithione  (ISO)
quercetin  (EXP,ISO)
quercitrin  (EXP)
raloxifene  (EXP)
reactive oxygen species  (ISO)
reserpine  (ISO)
resveratrol  (EXP,ISO)
riddelliine  (ISO)
rifampicin  (ISO)
rofecoxib  (EXP)
roxarsone  (EXP)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
salubrinal  (ISO)
SB 431542  (EXP)
Securinine  (EXP)
silver atom  (EXP)
silver(0)  (EXP)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sorafenib  (EXP)
sphingosine 1-phosphate  (EXP)
sulfasalazine  (EXP)
sulindac sulfide  (EXP)
Sunset Yellow FCF  (EXP)
tacrine  (ISO)
tamoxifen  (ISO)
taurochenodeoxycholic acid  (EXP)
taurocholic acid  (ISO)
telmisartan  (ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
thalidomide  (EXP)
thapsigargin  (ISO)
thioacetamide  (EXP,ISO)
titanium dioxide  (ISO)
trichloroethene  (ISO)
trichostatin A  (EXP)
triptonide  (ISO)
tunicamycin  (ISO)
ursodeoxycholic acid  (EXP,ISO)
valproic acid  (EXP)
valsartan  (ISO)
vanadium atom  (EXP)
vanadium(0)  (EXP)
vemurafenib  (EXP)
vorinostat  (EXP)
XAV939  (EXP)
zinc atom  (ISO)
zinc sulfate  (ISO)
zinc(0)  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
animal organ regeneration  (IEA,ISO)
cell chemotaxis  (IDA)
cell morphogenesis  (IEA,ISO)
cellular response to hepatocyte growth factor stimulus  (IDA)
epithelial cell proliferation  (IEA,ISO)
epithelial to mesenchymal transition  (TAS)
hepatocyte growth factor receptor signaling pathway  (IBA,IDA,IEA,ISO)
liver development  (IEA,ISO)
mitotic cell cycle  (NAS)
mitotic cell cycle  (NAS)
myoblast proliferation  (IEA,ISO)
negative regulation of apoptotic process  (IBA,IEA,ISO)
negative regulation of autophagy  (NAS)
negative regulation of cysteine-type endopeptidase activity involved in apoptotic process  (IDA)
negative regulation of extrinsic apoptotic signaling pathway via death domain receptors  (IEA,ISO)
negative regulation of hydrogen peroxide-mediated programmed cell death  (IDA)
negative regulation of inflammatory response  (IEA)
negative regulation of inflammatory response  (IEA)
negative regulation of inflammatory response  (ISO)
negative regulation of interleukin-6 production  (IEA,ISO)
negative regulation of peptidyl-serine phosphorylation  (IEA,ISO)
negative regulation of release of cytochrome c from mitochondria  (IDA)
positive chemotaxis  (IEA)
positive regulation of angiogenesis  (IEA,ISO)
positive regulation of cell migration  (IDA)
positive regulation of DNA biosynthetic process  (IDA)
positive regulation of interleukin-10 production  (IEA,ISO)
positive regulation of MAPK cascade  (IEA,ISO)
positive regulation of myelination  (IEA,ISO)
positive regulation of neuron projection regeneration  (IEA,ISO)
positive regulation of osteoblast differentiation  (NAS)
positive regulation of peptidyl-tyrosine phosphorylation  (IDA)
positive regulation of phosphatidylinositol 3-kinase signaling  (IDA)
positive regulation of protein phosphorylation  (IBA)
positive regulation of transcription by RNA polymerase II  (NAS)
proteolysis  (NAS)
regulation of branching involved in salivary gland morphogenesis by mesenchymal-epithelial signaling  (IDA,IEA)
regulation of p38MAPK cascade  (IEA,ISO)
regulation of tau-protein kinase activity  (IEA,ISO)
skeletal muscle cell proliferation  (IEA,ISO)

Cellular Component

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

References - curated
# Reference Title Reference Citation
1. Hepatocyte growth factor is associated with poor prognosis of malignant gliomas and is a predictor for recurrence of meningioma. Arrieta O, etal., Cancer. 2002 Jun 15;94(12):3210-8.
2. Hepatocellular carcinoma and cholangiocarcinoma are associated with high serum levels of hepatocyte growth factor. Balaban YH, etal., Indian J Gastroenterol. 2006 Jul-Aug;25(4):223-4.
3. Met, metastasis, motility and more. Birchmeier C, etal., Nat Rev Mol Cell Biol. 2003 Dec;4(12):915-25.
4. Active scatter factor (HGF/SF) in proliferative vitreoretinal disease. Briggs MC, etal., Invest Ophthalmol Vis Sci. 2000 Sep;41(10):3085-94.
5. c-MET pathway involvement in chronic rhinosinusitis: a genetic association analysis. Castano R, etal., Otolaryngol Head Neck Surg. 2010 May;142(5):665-71.e1-2. doi: 10.1016/j.otohns.2010.01.004.
6. Hepatocyte growth factor/scatter factor promotes retinal angiogenesis through increased urokinase expression. Colombo ES, etal., Invest Ophthalmol Vis Sci. 2007 Apr;48(4):1793-800.
7. Hepatocyte growth factor incorporated into herpes simplex virus vector accelerates facial nerve regeneration after crush injury. Esaki S, etal., Gene Ther. 2011 Nov;18(11):1063-9. doi: 10.1038/gt.2011.57. Epub 2011 May 12.
8. Differential gene expression of MMP-1, TIMP-1 and HGF in clinically involved and uninvolved skin in South Africans with SSc. Frost J, etal., Rheumatology (Oxford). 2012 Jun;51(6):1049-52. doi: 10.1093/rheumatology/ker367. Epub 2012 Jan 27.
9. The Met tyrosine kinase receptor in development and cancer. Gentile A, etal., Cancer Metastasis Rev. 2008 Mar;27(1):85-94.
10. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
11. Family-based association analysis of hepatocyte growth factor (HGF) gene polymorphisms in high myopia. Han W, etal., Invest Ophthalmol Vis Sci. 2006 Jun;47(6):2291-9.
12. Identification of novel cellular targets in biliary tract cancers using global gene expression technology. Hansel DE, etal., Am J Pathol. 2003 Jul;163(1):217-29.
13. Levels of vascular endothelial growth factor and hepatocyte growth factor in sera of patients with rheumatic diseases. Hashimoto N, etal., Mod Rheumatol. 2003 Jun;13(2):129-34. doi: 10.3109/s10165-002-0211-8.
14. Hepatocyte growth factor accelerates the proliferation of hepatic oval cells and possibly promotes the differentiation in a 2-acetylaminofluorene/partial hepatectomy model in rats. Hasuike S, etal., J Gastroenterol Hepatol. 2005 Nov;20(11):1753-61.
15. Intravitreous levels of hepatocyte growth factor/scatter factor and vascular cell adhesion molecule-1 in the vitreous fluid of diabetic patients with proliferative retinopathy. Hernandez C, etal., Diabetes Metab. 2004 Sep;30(4):341-6.
16. Strong association between serum hepatocyte growth factor and metabolic syndrome. Hiratsuka A, etal., J Clin Endocrinol Metab. 2005 May;90(5):2927-31. Epub 2005 Feb 15.
17. Association of hepatocyte growth factor promoter polymorphism with severity of interstitial lung disease in Japanese patients with systemic sclerosis. Hoshino K, etal., Arthritis Rheum. 2011 Aug;63(8):2465-72. doi: 10.1002/art.30415.
18. Differences in the temporal expression of regulatory growth factors during choroidal neovascular development. Hu W, etal., Exp Eye Res. 2009 Jan;88(1):79-91. doi: 10.1016/j.exer.2008.10.014. Epub 2008 Nov 1.
19. Hepatocyte growth factor ameliorates dermal sclerosis in the tight-skin mouse model of scleroderma. Iwasaki T, etal., Arthritis Res Ther. 2006;8(6):R161.
20. Hepatocyte growth factor genetic variations and primary angle-closure glaucoma in the Han Chinese population. Jiang Z, etal., PLoS One. 2013 Apr 9;8(4):e60950. doi: 10.1371/journal.pone.0060950. Print 2013.
21. [Serum hepatocyte growth factor (HGF) in patients with inflammatory myopathies]. Kadoya A, etal., Nihon Rinsho Meneki Gakkai Kaishi. 1996 Oct;19(5):488-97.
22. Hepatocyte growth factor gene therapy slows down the progression of diabetic nephropathy in db/db mice. Kagawa T, etal., Nephron Physiol. 2006;102(3-4):p92-102. Epub 2005 Dec 6.
23. Nonviral gene transfer of human hepatocyte growth factor improves streptozotocin-induced diabetic neuropathy in rats. Kato N, etal., Diabetes. 2005 Mar;54(3):846-54.
24. Reduced high serum hepatocyte growth factor levels after successful cardioversion in patients with atrial fibrillation. Katoh H, etal., Clin Exp Pharmacol Physiol. 2004 Mar;31(3):145-51.
25. Increase in the circulating level of hepatocyte growth factor in pancreatic cancer patients. Kemik O, etal., Bratisl Lek Listy. 2009;110(10):627-9.
26. c-Met expression as an indicator of survival outcome in patients with oral tongue carcinoma. Kim CH, etal., Head Neck. 2010 Dec;32(12):1655-64. doi: 10.1002/hed.21383.
27. Hepatocyte growth factor promotes endogenous repair and functional recovery after spinal cord injury. Kitamura K, etal., J Neurosci Res. 2007 Aug 15;85(11):2332-42.
28. Human hepatocyte growth factor promotes functional recovery in primates after spinal cord injury. Kitamura K, etal., PLoS One. 2011;6(11):e27706. doi: 10.1371/journal.pone.0027706. Epub 2011 Nov 29.
29. Role of fibroblast-derived growth factors in regulating hyperpigmentation of solar lentigo. Kovacs D, etal., Br J Dermatol. 2010 Nov;163(5):1020-7. doi: 10.1111/j.1365-2133.2010.09946.x.
30. Acceleration of wound healing by combined gene transfer of hepatocyte growth factor and prostacyclin synthase with Shima Jet. Kunugiza Y, etal., Gene Ther. 2006 Aug;13(15):1143-52. Epub 2006 Mar 30.
31. Suppression of progressive loss of coat color in microphthalmia-vitiligo mutant mice. Kurita K, etal., J Invest Dermatol. 2005 Sep;125(3):538-44.
32. Hepatocyte growth factor ameliorates acute graft-versus-host disease and promotes hematopoietic function. Kuroiwa T, etal., J Clin Invest. 2001 Jun;107(11):1365-73.
33. Unique epithelial cell production of hepatocyte growth factor/scatter factor by putative precancerous intestinal metaplasias and associated "intestinal-type" biliary cancer chemically induced in rat liver. Lai GH, etal., Hepatology. 2000 Jun;31(6):1257-65.
34. Vascular endothelial growth factor and hepatocyte growth factor levels are differentially elevated in patients with advanced retinopathy of prematurity. Lashkari K, etal., Am J Pathol. 2000 Apr;156(4):1337-44.
35. [Tubular epithelial-myofibroblast transdifferentiation and expressions of hepatocyte growth factor and Smad7 in renal tissues of rat with experimental diabetes] Liu QJ, etal., Zhongguo Wei Zhong Bing Ji Jiu Yi Xue. 2005 Nov;17(11):675-8.
36. Neuroprotective effect of hepatocyte growth factor against photoreceptor degeneration in rats. Machida S, etal., Invest Ophthalmol Vis Sci. 2004 Nov;45(11):4174-82.
37. Angiogenic gene cell therapy using suicide gene system regulates the effect of angiogenesis in infarcted rat heart. Miyagawa S, etal., Transplantation. 2006 Mar 27;81(6):902-7.
38. Safety evaluation of clinical gene therapy using hepatocyte growth factor to treat peripheral arterial disease. Morishita R, etal., Hypertension. 2004 Aug;44(2):203-9. Epub 2004 Jul 6.
39. Association between hepatocyte growth factor gene polymorphism and essential hypertension. Motone M, etal., Hypertens Res. 2004 Apr;27(4):247-51.
40. Co-expression of different angiogenic factors in external auditory canal cholesteatoma. Naim R, etal., Acta Otolaryngol. 2004 Jun;124(5):563-8.
41. Association between interleukin-15 and obesity: interleukin-15 as a potential regulator of fat mass. Nielsen AR, etal., J Clin Endocrinol Metab. 2008 Nov;93(11):4486-93. Epub 2008 Aug 12.
42. A novel nude mouse model of liver metastasis and peritoneal dissemination from the same human pancreatic cancer line. Nishimori H, etal., Pancreas. 2002 Apr;24(3):242-50.
43. Serum hepatocyte growth factor as a possible indicator of arteriosclerosis. Nishimura M, etal., J Hypertens. 1997 Oct;15(10):1137-42.
44. Accelerated ultraviolet radiation-induced carcinogenesis in hepatocyte growth factor/scatter factor transgenic mice. Noonan FP, etal., Cancer Res. 2000 Jul 15;60(14):3738-43.
45. A comparison of the levels of hepatocyte growth factor in serum in patients with type 1 diabetes mellitus with different stages of diabetic retinopathy. Nowak M, etal., Endokrynol Pol. 2008 Jan-Feb;59(1):2-5.
46. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
47. Online Mendelian Inheritance in Man, OMIM (TM). Online Mendelian Inheritance in Man, OMIM (TM).
48. Involvement of hepatocyte growth factor in the development of bone metastasis of a mouse mammary cancer cell line, BALB/c-MC. Ono K, etal., Bone. 2006 Jul;39(1):27-34. Epub 2006 Feb 3.
49. Intrathecal injection of HVJ-E containing HGF gene to cerebrospinal fluid can prevent and ameliorate hearing impairment in rats. Oshima K, etal., FASEB J. 2004 Jan;18(1):212-4. Epub 2003 Nov 20.
50. c-Met autocrine activation induces development of malignant melanoma and acquisition of the metastatic phenotype. Otsuka T, etal., Cancer Res. 1998 Nov 15;58(22):5157-67.
51. Disassociation of met-mediated biological responses in vivo: the natural hepatocyte growth factor/scatter factor splice variant NK2 antagonizes growth but facilitates metastasis. Otsuka T, etal., Mol Cell Biol. 2000 Mar;20(6):2055-65.
52. KEGG Annotation Import Pipeline Pipeline to import KEGG annotations from KEGG into RGD
53. PID Annotation Import Pipeline Pipeline to import Pathway Interaction Database annotations from NCI into RGD
54. Hepatocyte growth factor and c-MET in benign and malignant peripheral nerve sheath tumors. Rao UN, etal., Hum Pathol. 1997 Sep;28(9):1066-70.
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Additional References at PubMed
PMID:1280830   PMID:1321034   PMID:1328193   PMID:1334458   PMID:1386343   PMID:1482348   PMID:1531136   PMID:1535333   PMID:1655405   PMID:1720571   PMID:1824873   PMID:1826653  
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Genomics

Comparative Map Data
HGF
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38781,699,010 - 81,770,047 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl781,699,010 - 81,770,438 (-)EnsemblGRCh38hg38GRCh38
GRCh37781,328,326 - 81,399,363 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36781,169,380 - 81,237,388 (-)NCBINCBI36Build 36hg18NCBI36
Build 34781,024,867 - 81,044,103NCBI
Celera776,032,788 - 76,100,524 (-)NCBICelera
Cytogenetic Map7q21.11NCBI
HuRef775,935,402 - 76,003,191 (-)NCBIHuRef
CHM1_1781,261,794 - 81,329,511 (-)NCBICHM1_1
T2T-CHM13v2.0782,951,060 - 83,022,099 (-)NCBIT2T-CHM13v2.0
CRA_TCAGchr7v2780,663,506 - 80,731,238 (-)NCBI
Hgf
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39516,758,493 - 16,827,448 (+)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl516,758,493 - 16,825,150 (+)EnsemblGRCm39 Ensembl
GRCm38516,553,495 - 16,619,439 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl516,553,495 - 16,620,152 (+)EnsemblGRCm38mm10GRCm38
MGSCv37516,059,368 - 16,125,257 (+)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv36516,065,374 - 16,131,263 (+)NCBIMGSCv36mm8
Celera513,552,002 - 13,617,800 (+)NCBICelera
Cytogenetic Map5A3NCBI
cM Map57.07NCBI
Hgf
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.2418,673,736 - 18,745,582 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl418,677,101 - 18,745,409 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx423,828,584 - 23,896,754 (-)NCBIRnor_SHR
UTH_Rnor_SHRSP_BbbUtx_1.0419,645,467 - 19,713,646 (-)NCBIRnor_SHRSP
UTH_Rnor_WKY_Bbb_1.0418,026,554 - 18,094,730 (-)NCBIRnor_WKY
Rnor_6.0415,435,460 - 15,505,377 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl415,433,295 - 15,505,362 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.0415,408,857 - 15,478,988 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.4414,864,357 - 14,932,513 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.1414,864,356 - 14,932,513 (-)NCBI
Celera414,212,976 - 14,281,167 (-)NCBICelera
Cytogenetic Map4q12NCBI
Hgf
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049554104,114,778 - 4,182,058 (+)EnsemblChiLan1.0
ChiLan1.0NW_0049554104,114,280 - 4,181,953 (+)NCBIChiLan1.0ChiLan1.0
HGF
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1787,325,741 - 87,396,850 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl787,327,798 - 87,397,811 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0773,667,618 - 73,738,960 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
HGF
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.11821,329,688 - 21,410,257 (-)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl1821,332,817 - 21,410,263 (-)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha1821,005,145 - 21,082,437 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.01821,778,181 - 21,858,827 (-)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl1821,778,229 - 21,858,761 (-)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.11821,417,964 - 21,495,307 (-)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.01820,953,619 - 21,030,809 (-)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.01821,607,548 - 21,684,870 (-)NCBIUU_Cfam_GSD_1.0
Hgf
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440511863,151,279 - 63,227,083 (-)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936734356,115 - 428,779 (-)EnsemblSpeTri2.0
SpeTri2.0NW_004936734354,798 - 428,356 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
HGF
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl998,438,143 - 98,513,564 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1998,437,771 - 98,513,573 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.29108,765,929 - 108,841,386 (+)NCBISscrofa10.2Sscrofa10.2susScr3
HGF
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12167,118,785 - 67,193,506 (+)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl2167,120,722 - 67,193,504 (+)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_02366604236,762,736 - 36,834,784 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Hgf
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462473930,236,146 - 30,307,356 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462473930,233,589 - 30,307,508 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in HGF
152 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_000601.6(HGF):c.482+1986_482+1988del microsatellite Autosomal recessive nonsyndromic hearing loss 39 [RCV000016090] Chr7:81755201..81755203 [GRCh38]
Chr7:81384517..81384519 [GRCh37]
Chr7:7q21.11		 pathogenic
NM_000601.6(HGF):c.482+1991_482+2000del microsatellite Autosomal recessive nonsyndromic hearing loss 39 [RCV000016091] Chr7:81755189..81755198 [GRCh38]
Chr7:81384505..81384514 [GRCh37]
Chr7:7q21.11		 pathogenic
NM_000601.6(HGF):c.2011-50C>A single nucleotide variant not provided [RCV001545012] Chr7:81702807 [GRCh38]
Chr7:81332123 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.495G>A (p.Ser165=) single nucleotide variant Autosomal recessive nonsyndromic hearing loss 39 [RCV000016089] Chr7:81752250 [GRCh38]
Chr7:81381566 [GRCh37]
Chr7:7q21.11		 pathogenic
NM_000601.6(HGF):c.1008G>A (p.Glu336=) single nucleotide variant Autosomal recessive nonsyndromic hearing loss 39 [RCV000625228]|not provided [RCV000727188]|not specified [RCV000036550] Chr7:81729637 [GRCh38]
Chr7:81358953 [GRCh37]
Chr7:7q21.11		 benign|likely benign|conflicting interpretations of pathogenicity|uncertain significance
NM_000601.6(HGF):c.1272-4A>G single nucleotide variant Autosomal recessive nonsyndromic hearing loss 39 [RCV000624946]|Nonsyndromic Hearing Loss, Mixed [RCV000391680]|not provided [RCV002054590]|not specified [RCV000036551] Chr7:81717369 [GRCh38]
Chr7:81346685 [GRCh37]
Chr7:7q21.11		 benign|likely benign
NM_000601.6(HGF):c.1454T>C (p.Ile485Thr) single nucleotide variant not specified [RCV000036552] Chr7:81710234 [GRCh38]
Chr7:81339550 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.333A>G (p.Glu111=) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000327792]|not provided [RCV000711896]|not specified [RCV000036553] Chr7:81758726 [GRCh38]
Chr7:81388042 [GRCh37]
Chr7:7q21.11		 benign|likely benign
NM_000601.6(HGF):c.711T>C (p.His237=) single nucleotide variant not provided [RCV000965042]|not specified [RCV000036554] Chr7:81745035 [GRCh38]
Chr7:81374351 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.910G>A (p.Glu304Lys) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000276154]|not provided [RCV002054591]|not specified [RCV000036555] Chr7:81729735 [GRCh38]
Chr7:81359051 [GRCh37]
Chr7:7q21.11		 benign|likely benign
GRCh38/hg38 7q11.22-21.11(chr7:71225344-81735657)x1 copy number loss See cases [RCV000050709] Chr7:71225344..81735657 [GRCh38]
Chr7:70690330..81364973 [GRCh37]
Chr7:70328266..81202909 [NCBI36]
Chr7:7q11.22-21.11		 pathogenic
GRCh38/hg38 7p22.3-q36.3(chr7:53985-159282531)x1 copy number loss See cases [RCV000052250] Chr7:53985..159282531 [GRCh38]
Chr7:53985..159075220 [GRCh37]
Chr7:149068..158767981 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
GRCh38/hg38 7q21.11(chr7:81674792-84509195)x3 copy number gain Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052130]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052130]|See cases [RCV000052130] Chr7:81674792..84509195 [GRCh38]
Chr7:81304108..84138511 [GRCh37]
Chr7:81142044..83976447 [NCBI36]
Chr7:7q21.11		 uncertain significance
GRCh38/hg38 7q11.23-21.11(chr7:73873420-83988860)x1 copy number loss See cases [RCV000054118] Chr7:73873420..83988860 [GRCh38]
Chr7:73992744..83618176 [GRCh37]
Chr7:72925686..83456112 [NCBI36]
Chr7:7q11.23-21.11		 pathogenic
NM_000601.4(HGF):c.2130A>C (p.Ala710=) single nucleotide variant Malignant melanoma [RCV000067949] Chr7:81702638 [GRCh38]
Chr7:81331954 [GRCh37]
Chr7:81169890 [NCBI36]
Chr7:7q21.11		 not provided
NM_000601.4(HGF):c.255-299G>C single nucleotide variant Lung cancer [RCV000106512] Chr7:81759103 [GRCh38]
Chr7:81388419 [GRCh37]
Chr7:7q21.11		 uncertain significance
GRCh38/hg38 7p22.3-q36.3(chr7:54185-159282390)x1 copy number loss See cases [RCV000135401] Chr7:54185..159282390 [GRCh38]
Chr7:54185..159075079 [GRCh37]
Chr7:149268..158767840 [NCBI36]
Chr7:7p22.3-q36.3		 pathogenic
NM_000601.6(HGF):c.1832G>C (p.Ser611Thr) single nucleotide variant not provided [RCV000724490]|not specified [RCV000221502] Chr7:81705679 [GRCh38]
Chr7:81334995 [GRCh37]
Chr7:7q21.11		 likely benign|conflicting interpretations of pathogenicity|uncertain significance
NM_000601.6(HGF):c.1814C>T (p.Thr605Ile) single nucleotide variant not provided [RCV000724493]|not specified [RCV000218246] Chr7:81705697 [GRCh38]
Chr7:81335013 [GRCh37]
Chr7:7q21.11		 likely benign|conflicting interpretations of pathogenicity|uncertain significance
GRCh38/hg38 7q11.23-21.11(chr7:74377395-82031742)x1 copy number loss See cases [RCV000142381] Chr7:74377395..82031742 [GRCh38]
Chr7:73992744..81661058 [GRCh37]
Chr7:73429661..81498994 [NCBI36]
Chr7:7q11.23-21.11		 pathogenic
NM_000601.6(HGF):c.983G>T (p.Arg328Leu) single nucleotide variant Autosomal recessive nonsyndromic hearing loss 39 [RCV000477953]|not specified [RCV000150806] Chr7:81729662 [GRCh38]
Chr7:81358978 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.865+410dup duplication not specified [RCV000150807] Chr7:81742941..81742942 [GRCh38]
Chr7:81372257..81372258 [GRCh37]
Chr7:7q21.11		 pathogenic|not provided
NM_000601.6(HGF):c.1041-12T>C single nucleotide variant not specified [RCV000156675] Chr7:81726029 [GRCh38]
Chr7:81355345 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.682T>G (p.Ser228Ala) single nucleotide variant not provided [RCV001836738]|not specified [RCV000150808] Chr7:81745064 [GRCh38]
Chr7:81374380 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.659G>A (p.Arg220Gln) single nucleotide variant Inborn genetic diseases [RCV002514902]|not provided [RCV001762330]|not specified [RCV000150809] Chr7:81745087 [GRCh38]
Chr7:81374403 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1891G>A (p.Val631Met) single nucleotide variant Autosomal recessive nonsyndromic hearing loss 39 [RCV000987900]|not provided [RCV001719971]|not specified [RCV000155127] Chr7:81705509 [GRCh38]
Chr7:81334825 [GRCh37]
Chr7:7q21.11		 benign|likely benign|conflicting interpretations of pathogenicity|uncertain significance
NM_000601.6(HGF):c.270T>C (p.Asp90=) single nucleotide variant not provided [RCV000724491]|not specified [RCV000215168] Chr7:81758789 [GRCh38]
Chr7:81388105 [GRCh37]
Chr7:7q21.11		 likely benign|conflicting interpretations of pathogenicity|uncertain significance
Single allele deletion Seizure [RCV000240885] Chr7:81587754..84304468 [GRCh38]
Chr7:81217070..83933784 [GRCh37]
Chr7:7q21.11		 likely pathogenic
Single allele deletion Seizure [RCV000240951] Chr7:79708363..87161076 [GRCh38]
Chr7:79337679..86790392 [GRCh37]
Chr7:7q21.11-21.12		 pathogenic|likely pathogenic
NM_000601.6(HGF):c.471A>G (p.Pro157=) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000362654]|not provided [RCV001560919]|not specified [RCV000219529] Chr7:81757200 [GRCh38]
Chr7:81386516 [GRCh37]
Chr7:7q21.11		 likely benign|uncertain significance
NM_000601.6(HGF):c.1540A>G (p.Arg514Gly) single nucleotide variant not specified [RCV000220633] Chr7:81710148 [GRCh38]
Chr7:81339464 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.483-20G>A single nucleotide variant not specified [RCV000242069] Chr7:81752282 [GRCh38]
Chr7:81381598 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.88+9C>T single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000321516] Chr7:81769875 [GRCh38]
Chr7:81399191 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.*396A>T single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000285931] Chr7:81702185 [GRCh38]
Chr7:81331501 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.-40A>T single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000286375] Chr7:81770011 [GRCh38]
Chr7:81399327 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1715A>G (p.Tyr572Cys) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000355882] Chr7:81706329 [GRCh38]
Chr7:81335645 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.5(HGF):c.-94G>T single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000399680] Chr7:81770065 [GRCh38]
Chr7:81399381 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.4T>C (p.Trp2Arg) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000378490] Chr7:81769968 [GRCh38]
Chr7:81399284 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1041-6C>T single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000311558] Chr7:81726023 [GRCh38]
Chr7:81355339 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.800C>T (p.Pro267Leu) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000333616] Chr7:81743418 [GRCh38]
Chr7:81372734 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.-44A>G single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000334350] Chr7:81770015 [GRCh38]
Chr7:81399331 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.921A>C (p.Gln307His) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000368393] Chr7:81729724 [GRCh38]
Chr7:81359040 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1765G>A (p.Val589Ile) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000298690]|not provided [RCV000883919] Chr7:81705746 [GRCh38]
Chr7:81335062 [GRCh37]
Chr7:7q21.11		 benign|likely benign|uncertain significance
NM_000601.6(HGF):c.1904A>G (p.Tyr635Cys) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000391658] Chr7:81705496 [GRCh38]
Chr7:81334812 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.137C>T (p.Ala46Val) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000283216]|not provided [RCV000973134]|not specified [RCV000608266] Chr7:81762824 [GRCh38]
Chr7:81392140 [GRCh37]
Chr7:7q21.11		 benign|likely benign|uncertain significance
NM_000601.6(HGF):c.2019T>C (p.Tyr673=) single nucleotide variant not provided [RCV000303305] Chr7:81702749 [GRCh38]
Chr7:81332065 [GRCh37]
Chr7:7q21.11		 conflicting interpretations of pathogenicity|uncertain significance
NM_000601.6(HGF):c.438C>A (p.Gly146=) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000270369] Chr7:81757233 [GRCh38]
Chr7:81386549 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.754G>A (p.Asp252Asn) single nucleotide variant not provided [RCV002281324] Chr7:81743464 [GRCh38]
Chr7:81372780 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1445-152G>A single nucleotide variant not provided [RCV001567077] Chr7:81710395 [GRCh38]
Chr7:81339711 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.147C>G (p.Thr49=) single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000384633] Chr7:81762814 [GRCh38]
Chr7:81392130 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.*467A>G single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000374709] Chr7:81702114 [GRCh38]
Chr7:81331430 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.*101A>G single nucleotide variant Nonsyndromic Hearing Loss, Mixed [RCV000343182] Chr7:81702480 [GRCh38]
Chr7:81331796 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.717A>G (p.Thr239=) single nucleotide variant not provided [RCV000733016] Chr7:81745029 [GRCh38]
Chr7:81374345 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1675G>A (p.Glu559Lys) single nucleotide variant not provided [RCV000728416] Chr7:81706369 [GRCh38]
Chr7:81335685 [GRCh37]
Chr7:7q21.11		 uncertain significance
TMEM106B-BRAF fusion deletion Pleomorphic xanthoastrocytoma [RCV000454357] Chr7:12258147..140494267 [GRCh37]
Chr7:7p21.3-q34		 pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43360-159119707)x1 copy number loss See cases [RCV000446044] Chr7:43360..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7q21.11(chr7:81355319-81663832)x3 copy number gain See cases [RCV000447818] Chr7:81355319..81663832 [GRCh37]
Chr7:7q21.11		 likely benign
NC_000007.14:g.(?_81485635)_(84094822_?)del deletion Schizophrenia [RCV000416754] Chr7:81485635..84094822 [GRCh38]
Chr7:81114951..83724138 [GRCh37]
Chr7:80952887..83562074 [NCBI36]
Chr7:7q21.11		 likely pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707) copy number gain See cases [RCV000510686] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7q21.11(chr7:80348675-83666606)x1 copy number loss See cases [RCV000511923] Chr7:80348675..83666606 [GRCh37]
Chr7:7q21.11		 likely pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:43361-159119707)x3 copy number gain See cases [RCV000511549] Chr7:43361..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
NM_000601.6(HGF):c.258T>C (p.Ala86=) single nucleotide variant not provided [RCV000892097]|not specified [RCV000609442] Chr7:81758801 [GRCh38]
Chr7:81388117 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1934A>G (p.His645Arg) single nucleotide variant not specified [RCV000609946] Chr7:81705466 [GRCh38]
Chr7:81334782 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1406-3C>T single nucleotide variant not specified [RCV000615891] Chr7:81711522 [GRCh38]
Chr7:81340838 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.865+11G>A single nucleotide variant not provided [RCV002066826]|not specified [RCV000616912] Chr7:81743342 [GRCh38]
Chr7:81372658 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.146C>A (p.Thr49Asn) single nucleotide variant not specified [RCV000608473] Chr7:81762815 [GRCh38]
Chr7:81392131 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1818T>C (p.Ile606=) single nucleotide variant not specified [RCV000614331] Chr7:81705693 [GRCh38]
Chr7:81335009 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.2179C>T (p.Gln727Ter) single nucleotide variant not provided [RCV002532720]|not specified [RCV000601187] Chr7:81702589 [GRCh38]
Chr7:81331905 [GRCh37]
Chr7:7q21.11		 likely benign|uncertain significance
Single allele deletion not provided [RCV000677988] Chr7:73591993..93683437 [GRCh37]
Chr7:7q11.23-21.3		 uncertain significance
NM_000601.6(HGF):c.482+286_482+287insCCCTTT insertion not provided [RCV001566402] Chr7:81756902..81756903 [GRCh38]
Chr7:81386218..81386219 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.865+555C>A single nucleotide variant not provided [RCV001565564] Chr7:81742798 [GRCh38]
Chr7:81372114 [GRCh37]
Chr7:7q21.11		 likely benign
NC_000007.13:g.(20954043_21001537)_(114528369_114556605)inv inversion Childhood apraxia of speech [RCV000234948] Chr7:21001537..114528369 [GRCh37]
Chr7:7p15.3-q31.1		 pathogenic
NM_000601.6(HGF):c.483-153A>G single nucleotide variant not provided [RCV001539452] Chr7:81752415 [GRCh38]
Chr7:81381731 [GRCh37]
Chr7:7q21.11		 benign
GRCh37/hg19 7p22.3-q36.3(chr7:44935-159126310)x3 copy number gain not provided [RCV000746280] Chr7:44935..159126310 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
NC_000007.14:g.(?_81478831)_(84097791_?)del deletion Schizophrenia [RCV000754335] Chr7:81478831..84097791 [GRCh38]
Chr7:7q21.11		 likely pathogenic
GRCh37/hg19 7p22.3-q36.3(chr7:10704-159122532)x3 copy number gain not provided [RCV000746278] Chr7:10704..159122532 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
GRCh37/hg19 7q21.11(chr7:81026186-81466742)x3 copy number gain not provided [RCV000746846] Chr7:81026186..81466742 [GRCh37]
Chr7:7q21.11		 likely benign
GRCh37/hg19 7q21.11(chr7:81206169-81418596)x3 copy number gain not provided [RCV000746847] Chr7:81206169..81418596 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.1758-118del deletion not provided [RCV001681975] Chr7:81705871 [GRCh38]
Chr7:81335187 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.866-22del deletion Autosomal recessive nonsyndromic hearing loss 39 [RCV001703029]|not provided [RCV001651508] Chr7:81729801 [GRCh38]
Chr7:81359117 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.2011-160A>G single nucleotide variant not provided [RCV001571670] Chr7:81702917 [GRCh38]
Chr7:81332233 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1272-244C>T single nucleotide variant not provided [RCV001708505] Chr7:81717609 [GRCh38]
Chr7:81346925 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.368-46A>G single nucleotide variant not provided [RCV001565568] Chr7:81757349 [GRCh38]
Chr7:81386665 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1275T>C (p.His425=) single nucleotide variant not provided [RCV001584877] Chr7:81717362 [GRCh38]
Chr7:81346678 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.482+22G>A single nucleotide variant not provided [RCV001551686] Chr7:81757167 [GRCh38]
Chr7:81386483 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1168+231C>A single nucleotide variant not provided [RCV001566673] Chr7:81725659 [GRCh38]
Chr7:81354975 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.482+287_482+288insCTCTTT insertion not provided [RCV001648061] Chr7:81756901..81756902 [GRCh38]
Chr7:81386217..81386218 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.1662C>T (p.His554=) single nucleotide variant not provided [RCV000925507] Chr7:81706382 [GRCh38]
Chr7:81335698 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.762C>T (p.Gly254=) single nucleotide variant not provided [RCV000981529] Chr7:81743456 [GRCh38]
Chr7:81372772 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.1865-4C>T single nucleotide variant not provided [RCV000949312] Chr7:81705539 [GRCh38]
Chr7:81334855 [GRCh37]
Chr7:7q21.11		 likely benign
GRCh37/hg19 7p22.3-q36.3(chr7:10365-159119707)x3 copy number gain not provided [RCV000848126] Chr7:10365..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
NM_000601.6(HGF):c.594C>T (p.Tyr198=) single nucleotide variant not provided [RCV000922288] Chr7:81752151 [GRCh38]
Chr7:81381467 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.2016T>C (p.Asp672=) single nucleotide variant not provided [RCV000926596] Chr7:81702752 [GRCh38]
Chr7:81332068 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1627G>T (p.Asp543Tyr) single nucleotide variant not provided [RCV000841416] Chr7:81706417 [GRCh38]
Chr7:81335733 [GRCh37]
Chr7:7q21.11		 likely benign|conflicting interpretations of pathogenicity
NM_000601.6(HGF):c.1942G>A (p.Gly648Arg) single nucleotide variant not specified [RCV000825934] Chr7:81705458 [GRCh38]
Chr7:81334774 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.2011-3dup duplication not specified [RCV000825936] Chr7:81702759..81702760 [GRCh38]
Chr7:81332075..81332076 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1616+71G>T single nucleotide variant not provided [RCV000842921] Chr7:81707219 [GRCh38]
Chr7:81336535 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.885C>T (p.Asp295=) single nucleotide variant not provided [RCV000960894]|not specified [RCV001195193] Chr7:81729760 [GRCh38]
Chr7:81359076 [GRCh37]
Chr7:7q21.11		 likely benign
GRCh37/hg19 7q21.11(chr7:81075835-81387108)x3 copy number gain not provided [RCV000846300] Chr7:81075835..81387108 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.89-233A>G single nucleotide variant not provided [RCV001544909] Chr7:81763105 [GRCh38]
Chr7:81392421 [GRCh37]
Chr7:7q21.11		 likely benign
NC_000007.13:g.(?_81331897)_(81603888_?)dup duplication not provided [RCV003105266] Chr7:81331897..81603888 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1169-317C>T single nucleotide variant not provided [RCV001581067] Chr7:81721164 [GRCh38]
Chr7:81350480 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1617-175T>G single nucleotide variant not provided [RCV001571511] Chr7:81706602 [GRCh38]
Chr7:81335918 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1788G>A (p.Thr596_Ile597=) single nucleotide variant not provided [RCV003107082] Chr7:81705723 [GRCh38]
Chr7:81335039 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.2011-32T>G single nucleotide variant not provided [RCV001588570] Chr7:81702789 [GRCh38]
Chr7:81332105 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1040+209C>T single nucleotide variant not provided [RCV001638590] Chr7:81729396 [GRCh38]
Chr7:81358712 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.626-318C>T single nucleotide variant not provided [RCV001560537] Chr7:81745438 [GRCh38]
Chr7:81374754 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1168+140C>T single nucleotide variant not provided [RCV001680958] Chr7:81725750 [GRCh38]
Chr7:81355066 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.1541+221T>C single nucleotide variant not provided [RCV001555461] Chr7:81709926 [GRCh38]
Chr7:81339242 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.625+241C>T single nucleotide variant not provided [RCV001591509] Chr7:81751879 [GRCh38]
Chr7:81381195 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.2011-78C>A single nucleotide variant not provided [RCV001648333] Chr7:81702835 [GRCh38]
Chr7:81332151 [GRCh37]
Chr7:7q21.11		 benign
Single allele single nucleotide variant not provided [RCV001555801] Chr7:81770271 [GRCh38]
Chr7:81399587 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1041-339A>G single nucleotide variant not provided [RCV001561330] Chr7:81726356 [GRCh38]
Chr7:81355672 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.483-35C>T single nucleotide variant not provided [RCV001598534] Chr7:81752297 [GRCh38]
Chr7:81381613 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1169-303T>C single nucleotide variant not provided [RCV001621368] Chr7:81721150 [GRCh38]
Chr7:81350466 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.1271+209T>C single nucleotide variant not provided [RCV001562043] Chr7:81720536 [GRCh38]
Chr7:81349852 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1405+256T>C single nucleotide variant not provided [RCV001656093] Chr7:81716976 [GRCh38]
Chr7:81346292 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.1169-282G>A single nucleotide variant not provided [RCV001682395] Chr7:81721129 [GRCh38]
Chr7:81350445 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.1271+190A>T single nucleotide variant not provided [RCV001564622] Chr7:81720555 [GRCh38]
Chr7:81349871 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1616+22T>C single nucleotide variant not provided [RCV001571581] Chr7:81707268 [GRCh38]
Chr7:81336584 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1041-319T>C single nucleotide variant not provided [RCV001557956] Chr7:81726336 [GRCh38]
Chr7:81355652 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1757+143G>A single nucleotide variant not provided [RCV001640052] Chr7:81706144 [GRCh38]
Chr7:81335460 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.1758-119_1758-118del deletion not provided [RCV001568012] Chr7:81705871..81705872 [GRCh38]
Chr7:81335187..81335188 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1272-120A>G single nucleotide variant not provided [RCV001558458] Chr7:81717485 [GRCh38]
Chr7:81346801 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1616+167A>G single nucleotide variant not provided [RCV001678600] Chr7:81707123 [GRCh38]
Chr7:81336439 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.746+27A>G single nucleotide variant not provided [RCV001558883] Chr7:81744973 [GRCh38]
Chr7:81374289 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.625+110G>A single nucleotide variant not provided [RCV001620997] Chr7:81752010 [GRCh38]
Chr7:81381326 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.254+27A>G single nucleotide variant not provided [RCV001547223] Chr7:81762680 [GRCh38]
Chr7:81391996 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1865-12_1865-6del deletion not provided [RCV000949313] Chr7:81705541..81705547 [GRCh38]
Chr7:81334857..81334863 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1704C>T (p.Ser568=) single nucleotide variant not provided [RCV000925652] Chr7:81706340 [GRCh38]
Chr7:81335656 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1542-214T>G single nucleotide variant not provided [RCV001556913] Chr7:81707578 [GRCh38]
Chr7:81336894 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1169-332C>T single nucleotide variant not provided [RCV001620963] Chr7:81721179 [GRCh38]
Chr7:81350495 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.865+217T>C single nucleotide variant not provided [RCV001637145] Chr7:81743136 [GRCh38]
Chr7:81372452 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.865+73A>G single nucleotide variant not provided [RCV001558069] Chr7:81743280 [GRCh38]
Chr7:81372596 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.747-214T>C single nucleotide variant not provided [RCV001558073] Chr7:81743685 [GRCh38]
Chr7:81373001 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.2011-140A>G single nucleotide variant not provided [RCV001593917] Chr7:81702897 [GRCh38]
Chr7:81332213 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1617-154G>C single nucleotide variant not provided [RCV001553340] Chr7:81706581 [GRCh38]
Chr7:81335897 [GRCh37]
Chr7:7q21.11		 likely benign
Single allele single nucleotide variant not provided [RCV001553506] Chr7:81770189 [GRCh38]
Chr7:81399505 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1617-34T>C single nucleotide variant not provided [RCV001576043] Chr7:81706461 [GRCh38]
Chr7:81335777 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1041-169A>T single nucleotide variant not provided [RCV001638989] Chr7:81726186 [GRCh38]
Chr7:81355502 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.1405+128C>T single nucleotide variant not provided [RCV001714022] Chr7:81717104 [GRCh38]
Chr7:81346420 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.865+513T>C single nucleotide variant not provided [RCV001620605] Chr7:81742840 [GRCh38]
Chr7:81372156 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.1444+290C>T single nucleotide variant not provided [RCV001587141] Chr7:81711191 [GRCh38]
Chr7:81340507 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.89-22T>A single nucleotide variant not provided [RCV001590160] Chr7:81762894 [GRCh38]
Chr7:81392210 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.482+61A>T single nucleotide variant not provided [RCV001587513] Chr7:81757128 [GRCh38]
Chr7:81386444 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.88+153dup duplication not provided [RCV001614272] Chr7:81769724..81769725 [GRCh38]
Chr7:81399040..81399041 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.1541+159T>G single nucleotide variant not provided [RCV001710686] Chr7:81709988 [GRCh38]
Chr7:81339304 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.254+188G>A single nucleotide variant not provided [RCV001682603] Chr7:81762519 [GRCh38]
Chr7:81391835 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.865+590T>C single nucleotide variant not provided [RCV001670384] Chr7:81742763 [GRCh38]
Chr7:81372079 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.1444+282G>A single nucleotide variant not provided [RCV001589437] Chr7:81711199 [GRCh38]
Chr7:81340515 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1169-60C>T single nucleotide variant not provided [RCV001645309] Chr7:81720907 [GRCh38]
Chr7:81350223 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.483-81C>T single nucleotide variant not provided [RCV001586995] Chr7:81752343 [GRCh38]
Chr7:81381659 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1617-289A>C single nucleotide variant not provided [RCV001547838] Chr7:81706716 [GRCh38]
Chr7:81336032 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.754G>C (p.Asp252His) single nucleotide variant not specified [RCV001195382] Chr7:81743464 [GRCh38]
Chr7:81372780 [GRCh37]
Chr7:7q21.11		 uncertain significance
Single allele complex Ring chromosome 7 [RCV002280646] Chr7:43360..159119707 [GRCh37]
Chr7:7p22.3-q36.3		 pathogenic
NM_000601.6(HGF):c.1295C>T (p.Ala432Val) single nucleotide variant not provided [RCV001289448] Chr7:81717342 [GRCh38]
Chr7:81346658 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1169-45T>C single nucleotide variant not provided [RCV001642145] Chr7:81720892 [GRCh38]
Chr7:81350208 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.229A>G (p.Asn77Asp) single nucleotide variant not provided [RCV001355257] Chr7:81762732 [GRCh38]
Chr7:81392048 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.2183C>A (p.Ser728Ter) single nucleotide variant Hearing impairment [RCV001375429] Chr7:81702585 [GRCh38]
Chr7:81331901 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1343A>G (p.His448Arg) single nucleotide variant not specified [RCV001449763] Chr7:81717294 [GRCh38]
Chr7:81346610 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1541+256G>A single nucleotide variant not provided [RCV001534080] Chr7:81709891 [GRCh38]
Chr7:81339207 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.626-64C>G single nucleotide variant not provided [RCV001612591] Chr7:81745184 [GRCh38]
Chr7:81374500 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.1758-261C>A single nucleotide variant not provided [RCV001586963] Chr7:81706014 [GRCh38]
Chr7:81335330 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1041-116A>T single nucleotide variant not provided [RCV001674122] Chr7:81726133 [GRCh38]
Chr7:81355449 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.865+622T>C single nucleotide variant not provided [RCV001665986] Chr7:81742731 [GRCh38]
Chr7:81372047 [GRCh37]
Chr7:7q21.11		 benign
NM_000601.6(HGF):c.2010+6A>G single nucleotide variant not provided [RCV001590593] Chr7:81705384 [GRCh38]
Chr7:81334700 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.6G>T (p.Trp2Cys) single nucleotide variant not provided [RCV001752217] Chr7:81769966 [GRCh38]
Chr7:81399282 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.725G>A (p.Arg242Gln) single nucleotide variant not provided [RCV001779734] Chr7:81745021 [GRCh38]
Chr7:81374337 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.2123G>A (p.Arg708Gln) single nucleotide variant not provided [RCV001863965] Chr7:81702645 [GRCh38]
Chr7:81331961 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1403G>A (p.Arg468His) single nucleotide variant not provided [RCV002024208] Chr7:81717234 [GRCh38]
Chr7:81346550 [GRCh37]
Chr7:7q21.11		 uncertain significance
GRCh37/hg19 7q11.23-21.11(chr7:77310644-84461089) copy number loss not specified [RCV002053699] Chr7:77310644..84461089 [GRCh37]
Chr7:7q11.23-21.11		 pathogenic
GRCh37/hg19 7q21.11(chr7:78430626-82605557) copy number loss not specified [RCV002053703] Chr7:78430626..82605557 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1602G>C (p.Gln534His) single nucleotide variant not provided [RCV001969363] Chr7:81707304 [GRCh38]
Chr7:81336620 [GRCh37]
Chr7:7q21.11		 uncertain significance
GRCh37/hg19 7q21.11-21.3(chr7:77821356-93340137) copy number gain not specified [RCV002053701] Chr7:77821356..93340137 [GRCh37]
Chr7:7q21.11-21.3		 pathogenic
NM_000601.6(HGF):c.2146A>C (p.Ile716Leu) single nucleotide variant not provided [RCV001968648] Chr7:81702622 [GRCh38]
Chr7:81331938 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1816A>G (p.Ile606Val) single nucleotide variant not provided [RCV001990486] Chr7:81705695 [GRCh38]
Chr7:81335011 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1403G>C (p.Arg468Pro) single nucleotide variant not provided [RCV002049093] Chr7:81717234 [GRCh38]
Chr7:81346550 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1595C>T (p.Ala532Val) single nucleotide variant not provided [RCV001915839] Chr7:81707311 [GRCh38]
Chr7:81336627 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.751C>G (p.Pro251Ala) single nucleotide variant not provided [RCV002028923] Chr7:81743467 [GRCh38]
Chr7:81372783 [GRCh37]
Chr7:7q21.11		 uncertain significance
NC_000007.13:g.(?_80276057)_(83739925_?)del deletion not provided [RCV001960659] Chr7:80276057..83739925 [GRCh37]
Chr7:7q21.11		 pathogenic
NM_000601.6(HGF):c.389T>C (p.Ile130Thr) single nucleotide variant not provided [RCV001996264] Chr7:81757282 [GRCh38]
Chr7:81386598 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.724C>T (p.Arg242Trp) single nucleotide variant Inborn genetic diseases [RCV002553617]|not provided [RCV001882075] Chr7:81745022 [GRCh38]
Chr7:81374338 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1666A>G (p.Arg556Gly) single nucleotide variant not provided [RCV001975488] Chr7:81706378 [GRCh38]
Chr7:81335694 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.2095A>G (p.Ile699Val) single nucleotide variant not provided [RCV001936047] Chr7:81702673 [GRCh38]
Chr7:81331989 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1981G>A (p.Ala661Thr) single nucleotide variant not provided [RCV001974798] Chr7:81705419 [GRCh38]
Chr7:81334735 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1768C>G (p.Leu590Val) single nucleotide variant not provided [RCV001977919] Chr7:81705743 [GRCh38]
Chr7:81335059 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1421C>A (p.Thr474Lys) single nucleotide variant not provided [RCV002032105] Chr7:81711504 [GRCh38]
Chr7:81340820 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1405+11T>C single nucleotide variant not provided [RCV002148921] Chr7:81717221 [GRCh38]
Chr7:81346537 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.21G>T (p.Leu7=) single nucleotide variant not provided [RCV002149683] Chr7:81769951 [GRCh38]
Chr7:81399267 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1865-12G>A single nucleotide variant not provided [RCV002135274] Chr7:81705547 [GRCh38]
Chr7:81334863 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.625+20A>G single nucleotide variant not provided [RCV002213216] Chr7:81752100 [GRCh38]
Chr7:81381416 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.747-17C>G single nucleotide variant not provided [RCV002136525] Chr7:81743488 [GRCh38]
Chr7:81372804 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1272-17G>C single nucleotide variant not provided [RCV002142506] Chr7:81717382 [GRCh38]
Chr7:81346698 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.626-17_626-16dup duplication not provided [RCV002217069] Chr7:81745135..81745136 [GRCh38]
Chr7:81374451..81374452 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1444+7A>T single nucleotide variant not provided [RCV002157884] Chr7:81711474 [GRCh38]
Chr7:81340790 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1272-17G>T single nucleotide variant not provided [RCV002098907] Chr7:81717382 [GRCh38]
Chr7:81346698 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1272-5_1272-4inv inversion not provided [RCV003114707] Chr7:81717369..81717370 [GRCh38]
Chr7:81346685..81346686 [GRCh37]
Chr7:7q21.11		 uncertain significance
NC_000007.13:g.(?_81331897)_(84751207_?)dup duplication CHARGE association [RCV003116599] Chr7:81331897..84751207 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.104GAA[1] (p.Arg36del) microsatellite not provided [RCV002274746] Chr7:81762852..81762854 [GRCh38]
Chr7:81392168..81392170 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.2084G>A (p.Arg695His) single nucleotide variant not provided [RCV002286288] Chr7:81702684 [GRCh38]
Chr7:81332000 [GRCh37]
Chr7:7q21.11		 uncertain significance
GRCh37/hg19 7p22.3-q36.3(chr7:56604613-96692931)x1 copy number loss See cases [RCV002287832] Chr7:56604613..96692931 [GRCh37]
Chr7:7p22.3-q36.3		 uncertain significance
NM_000601.6(HGF):c.2105G>A (p.Arg702His) single nucleotide variant not provided [RCV002469768] Chr7:81702663 [GRCh38]
Chr7:81331979 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1810T>C (p.Cys604Arg) single nucleotide variant Autosomal recessive nonsyndromic hearing loss 39 [RCV002465061] Chr7:81705701 [GRCh38]
Chr7:81335017 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1470G>A (p.Thr490_Lys491=) single nucleotide variant not provided [RCV002616631] Chr7:81710218 [GRCh38]
Chr7:81339534 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1685A>G (p.Lys562Arg) single nucleotide variant not provided [RCV002636141] Chr7:81706359 [GRCh38]
Chr7:81335675 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.367+17T>C single nucleotide variant not provided [RCV002881540] Chr7:81758675 [GRCh38]
Chr7:81387991 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1953_1954insGAATGAGT (p.Leu652delinsGluTer) insertion not provided [RCV002903561] Chr7:81705446..81705447 [GRCh38]
Chr7:81334762..81334763 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1951A>T (p.Thr651Ser) single nucleotide variant not provided [RCV002903562] Chr7:81705449 [GRCh38]
Chr7:81334765 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.104G>T (p.Arg35Ile) single nucleotide variant not provided [RCV002726444] Chr7:81762857 [GRCh38]
Chr7:81392173 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1272T>C (p.Arg424_His425=) single nucleotide variant not provided [RCV002847621] Chr7:81717365 [GRCh38]
Chr7:81346681 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.483-17T>A single nucleotide variant not provided [RCV002591224] Chr7:81752279 [GRCh38]
Chr7:81381595 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.758A>G (p.Lys253Arg) single nucleotide variant Inborn genetic diseases [RCV002660408] Chr7:81743460 [GRCh38]
Chr7:81372776 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1372C>T (p.Leu458Phe) single nucleotide variant not provided [RCV002871013] Chr7:81717265 [GRCh38]
Chr7:81346581 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1469C>T (p.Thr490Met) single nucleotide variant not provided [RCV002637444] Chr7:81710219 [GRCh38]
Chr7:81339535 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1406-10A>G single nucleotide variant not provided [RCV002570058] Chr7:81711529 [GRCh38]
Chr7:81340845 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1677G>C (p.Glu559Asp) single nucleotide variant Inborn genetic diseases [RCV002742577] Chr7:81706367 [GRCh38]
Chr7:81335683 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1884A>G (p.Leu628_Leu629=) single nucleotide variant not provided [RCV003022402] Chr7:81705516 [GRCh38]
Chr7:81334832 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1605T>C (p.Cys535_Phe536=) single nucleotide variant not provided [RCV002982552] Chr7:81707301 [GRCh38]
Chr7:81336617 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.579T>C (p.Asn193_Pro194=) single nucleotide variant not provided [RCV002667456] Chr7:81752166 [GRCh38]
Chr7:81381482 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.899T>G (p.Leu300Trp) single nucleotide variant not provided [RCV002958382] Chr7:81729746 [GRCh38]
Chr7:81359062 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.182C>A (p.Thr61Asn) single nucleotide variant Inborn genetic diseases [RCV002789496] Chr7:81762779 [GRCh38]
Chr7:81392095 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1049G>A (p.Arg350Gln) single nucleotide variant Inborn genetic diseases [RCV002666008] Chr7:81726009 [GRCh38]
Chr7:81355325 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.2011G>C (p.Gly671Arg) single nucleotide variant not provided [RCV002938311] Chr7:81702757 [GRCh38]
Chr7:81332073 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1274A>T (p.His425Leu) single nucleotide variant not provided [RCV002646621] Chr7:81717363 [GRCh38]
Chr7:81346679 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.626-7T>G single nucleotide variant not provided [RCV002646779] Chr7:81745127 [GRCh38]
Chr7:81374443 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.1405+20G>C single nucleotide variant not provided [RCV002597863] Chr7:81717212 [GRCh38]
Chr7:81346528 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.983G>A (p.Arg328His) single nucleotide variant not provided [RCV002959239] Chr7:81729662 [GRCh38]
Chr7:81358978 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.482+5G>C single nucleotide variant not provided [RCV002966110] Chr7:81757184 [GRCh38]
Chr7:81386500 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.508A>G (p.Lys170Glu) single nucleotide variant not provided [RCV002582374] Chr7:81752237 [GRCh38]
Chr7:81381553 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.7G>C (p.Val3Leu) single nucleotide variant not provided [RCV002634352] Chr7:81769965 [GRCh38]
Chr7:81399281 [GRCh37]
Chr7:7q21.11		 uncertain significance
NM_000601.6(HGF):c.1005C>T (p.His335_Glu336=) single nucleotide variant not provided [RCV002583757] Chr7:81729640 [GRCh38]
Chr7:81358956 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.474C>T (p.His158_Glu159=) single nucleotide variant not provided [RCV002585616] Chr7:81757197 [GRCh38]
Chr7:81386513 [GRCh37]
Chr7:7q21.11		 likely benign
NM_000601.6(HGF):c.753C>T (p.Pro251_Asp252=) single nucleotide variant not provided [RCV002611947] Chr7:81743465 [GRCh38]
Chr7:81372781 [GRCh37]
Chr7:7q21.11		 likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2994
Count of miRNA genes:1144
Interacting mature miRNAs:1412
Transcripts:ENST00000222390, ENST00000354224, ENST00000412881, ENST00000421558, ENST00000423064, ENST00000444829, ENST00000453018, ENST00000453411, ENST00000457544, ENST00000465234
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D7S644  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37786,285,031 - 86,285,230UniSTSGRCh37
GRCh37786,285,002 - 86,285,128UniSTSGRCh37
Build 36786,122,967 - 86,123,166RGDNCBI36
Celera780,988,976 - 80,989,102UniSTS
Celera780,989,005 - 80,989,203RGD
Cytogenetic Map7q21.1-q21.2UniSTS
Cytogenetic Map7q21.1UniSTS
HuRef780,896,264 - 80,896,461UniSTS
HuRef780,896,235 - 80,896,361UniSTS
CRA_TCAGchr7v2785,616,734 - 85,616,860UniSTS
CRA_TCAGchr7v2785,616,763 - 85,616,960UniSTS
Marshfield Genetic Map797.89RGD
Genethon Genetic Map798.3UniSTS
deCODE Assembly Map799.02UniSTS
GeneMap99-GB4 RH Map7475.84UniSTS
Whitehead-RH Map7448.8UniSTS
Whitehead-YAC Contig Map7 UniSTS
D7S3046  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37768,552,322 - 68,552,658UniSTSGRCh37
Build 36768,190,258 - 68,190,594RGDNCBI36
Celera761,933,512 - 61,933,848RGD
Cytogenetic Map7q21.1UniSTS
HuRef764,732,533 - 64,732,857UniSTS
CRA_TCAGchr7v2767,891,243 - 67,891,571UniSTS
Marshfield Genetic Map778.65UniSTS
Marshfield Genetic Map778.65RGD
RH47062  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37781,328,427 - 81,328,572UniSTSGRCh37
Build 36781,166,363 - 81,166,508RGDNCBI36
Celera776,029,771 - 76,029,916RGD
Cytogenetic Map7q21.1UniSTS
HuRef775,932,385 - 75,932,530UniSTS
CRA_TCAGchr7v2780,660,489 - 80,660,634UniSTS
GeneMap99-GB4 RH Map7458.7UniSTS
D7S804  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37781,064,729 - 81,064,830UniSTSGRCh37
GRCh37781,366,149 - 81,366,270UniSTSGRCh37
GRCh37781,343,274 - 81,343,356UniSTSGRCh37
GRCh37781,389,974 - 81,390,062UniSTSGRCh37
Build 36781,204,085 - 81,204,206RGDNCBI36
Celera776,091,046 - 76,091,134UniSTS
Celera776,044,622 - 76,044,704UniSTS
Celera776,067,221 - 76,067,342RGD
Celera775,766,127 - 75,766,228UniSTS
HuRef775,668,736 - 75,668,837UniSTS
HuRef775,969,896 - 75,970,017UniSTS
HuRef775,993,717 - 75,993,801UniSTS
HuRef775,947,236 - 75,947,318UniSTS
CRA_TCAGchr7v2780,697,935 - 80,698,056UniSTS
CRA_TCAGchr7v2780,721,760 - 80,721,848UniSTS
CRA_TCAGchr7v2780,396,832 - 80,396,933UniSTS
CRA_TCAGchr7v2780,675,336 - 80,675,418UniSTS
Marshfield Genetic Map794.87UniSTS
Marshfield Genetic Map793.63UniSTS
Marshfield Genetic Map794.4UniSTS
deCODE Assembly Map793.99UniSTS
SHGC-84463  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37781,400,699 - 81,400,901UniSTSGRCh37
Build 36781,238,635 - 81,238,837RGDNCBI36
Celera776,101,769 - 76,101,971RGD
Cytogenetic Map7q21.1UniSTS
HuRef776,004,437 - 76,004,639UniSTS
CRA_TCAGchr7v2780,732,484 - 80,732,686UniSTS
TNG Radiation Hybrid Map735188.0UniSTS
G66820  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37781,391,413 - 81,391,740UniSTSGRCh37
Build 36781,229,349 - 81,229,676RGDNCBI36
Celera776,092,485 - 76,092,812RGD
Cytogenetic Map7q21.1UniSTS
HuRef775,995,152 - 75,995,479UniSTS
CRA_TCAGchr7v2780,723,199 - 80,723,526UniSTS
SHGC-31157  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37781,384,089 - 81,384,213UniSTSGRCh37
Build 36781,222,025 - 81,222,149RGDNCBI36
Celera776,085,161 - 76,085,285RGD
Cytogenetic Map7q21.1UniSTS
HuRef775,987,832 - 75,987,956UniSTS
CRA_TCAGchr7v2780,715,875 - 80,715,999UniSTS
GeneMap99-GB4 RH Map7455.6UniSTS
Whitehead-RH Map7433.3UniSTS
NCBI RH Map7968.3UniSTS
D7S2748  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37781,331,554 - 81,331,880UniSTSGRCh37
Build 36781,169,490 - 81,169,816RGDNCBI36
Celera776,032,898 - 76,033,224RGD
Cytogenetic Map7q21.1UniSTS
HuRef775,935,512 - 75,935,838UniSTS
CRA_TCAGchr7v2780,663,616 - 80,663,942UniSTS
TNG Radiation Hybrid Map735218.0UniSTS
Stanford-G3 RH Map73825.0UniSTS
NCBI RH Map7967.8UniSTS
GeneMap99-G3 RH Map73825.0UniSTS
STS-AA015815  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7q21.1UniSTS
GeneMap99-GB4 RH Map7458.7UniSTS
D7S804  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7q21.1UniSTS
Marshfield Genetic Map794.87UniSTS
deCODE Assembly Map793.99UniSTS
D7S804  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map7q21.1UniSTS
Marshfield Genetic Map794.4UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High 1 1
Medium 66 356 264 72 48 73 262 35 84 35 108 531 139 213 2
Low 2088 2279 1392 507 1183 352 2498 1262 1985 295 1126 870 156 1062 1588 2
Below cutoff 177 347 51 34 442 27 1526 870 1634 52 135 59 12 1 3 987

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_016274 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_000601 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001010931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001010932 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001010933 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001010934 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006715956 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011516115 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017012097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017012098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047420293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB208900 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC004960 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH005424 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK291674 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK313694 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AV701693 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX451992 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY246560 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC022308 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC063485 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC105797 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC130284 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC130286 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM153501 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BM971901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BU533235 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX495370 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH236949 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471091 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068271 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D90334 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ830861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  FJ830862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L02931 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M29145 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M55379 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M60718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M73239 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M73240 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  M77227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U46010 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X16323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X57574 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000222390   ⟹   ENSP00000222390
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,699,010 - 81,770,047 (-)Ensembl
RefSeq Acc Id: ENST00000354224   ⟹   ENSP00000346164
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,755,121 - 81,769,971 (-)Ensembl
RefSeq Acc Id: ENST00000412881   ⟹   ENSP00000396307
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,757,246 - 81,770,398 (-)Ensembl
RefSeq Acc Id: ENST00000421558   ⟹   ENSP00000388592
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,758,704 - 81,770,438 (-)Ensembl
RefSeq Acc Id: ENST00000423064   ⟹   ENSP00000413829
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,750,889 - 81,770,136 (-)Ensembl
RefSeq Acc Id: ENST00000444829   ⟹   ENSP00000389854
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,742,691 - 81,770,048 (-)Ensembl
RefSeq Acc Id: ENST00000453018
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,756,986 - 81,762,996 (-)Ensembl
RefSeq Acc Id: ENST00000453411   ⟹   ENSP00000408270
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,742,732 - 81,770,047 (-)Ensembl
RefSeq Acc Id: ENST00000457544   ⟹   ENSP00000391238
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,702,127 - 81,770,048 (-)Ensembl
RefSeq Acc Id: ENST00000465234   ⟹   ENSP00000494355
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,751,916 - 81,770,024 (-)Ensembl
RefSeq Acc Id: ENST00000643024   ⟹   ENSP00000496217
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl781,755,121 - 81,769,971 (-)Ensembl
RefSeq Acc Id: NM_000601   ⟹   NP_000592
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,699,010 - 81,770,047 (-)NCBI
GRCh37781,331,444 - 81,399,452 (-)ENTREZGENE
Build 36781,169,380 - 81,237,388 (-)NCBI Archive
HuRef775,935,402 - 76,003,191 (-)ENTREZGENE
CHM1_1781,258,674 - 81,329,573 (-)NCBI
T2T-CHM13v2.0782,951,060 - 83,022,099 (-)NCBI
CRA_TCAGchr7v2780,663,506 - 80,731,238 (-)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001010931   ⟹   NP_001010931
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,742,691 - 81,770,047 (-)NCBI
GRCh37781,331,444 - 81,399,452 (-)ENTREZGENE
Build 36781,209,943 - 81,237,388 (-)NCBI Archive
HuRef775,935,402 - 76,003,191 (-)ENTREZGENE
CHM1_1781,302,069 - 81,329,573 (-)NCBI
T2T-CHM13v2.0782,994,743 - 83,022,099 (-)NCBI
CRA_TCAGchr7v2780,663,506 - 80,731,238 (-)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001010932   ⟹   NP_001010932
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,699,010 - 81,770,047 (-)NCBI
GRCh37781,331,444 - 81,399,452 (-)ENTREZGENE
Build 36781,169,380 - 81,237,388 (-)NCBI Archive
HuRef775,935,402 - 76,003,191 (-)ENTREZGENE
CHM1_1781,258,674 - 81,329,573 (-)NCBI
T2T-CHM13v2.0782,951,060 - 83,022,099 (-)NCBI
CRA_TCAGchr7v2780,663,506 - 80,731,238 (-)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001010933   ⟹   NP_001010933
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,742,691 - 81,770,047 (-)NCBI
GRCh37781,331,444 - 81,399,452 (-)ENTREZGENE
Build 36781,209,943 - 81,237,388 (-)NCBI Archive
HuRef775,935,402 - 76,003,191 (-)ENTREZGENE
CHM1_1781,302,069 - 81,329,573 (-)NCBI
T2T-CHM13v2.0782,994,743 - 83,022,099 (-)NCBI
CRA_TCAGchr7v2780,663,506 - 80,731,238 (-)ENTREZGENE
Sequence:
RefSeq Acc Id: NM_001010934   ⟹   NP_001010934
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,750,900 - 81,770,047 (-)NCBI
GRCh37781,331,444 - 81,399,452 (-)ENTREZGENE
Build 36781,218,152 - 81,237,388 (-)NCBI Archive
HuRef775,935,402 - 76,003,191 (-)ENTREZGENE
CHM1_1781,310,281 - 81,329,573 (-)NCBI
T2T-CHM13v2.0783,002,952 - 83,022,099 (-)NCBI
CRA_TCAGchr7v2780,663,506 - 80,731,238 (-)ENTREZGENE
Sequence:
RefSeq Acc Id: XM_047420293   ⟹   XP_047276249
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,741,999 - 81,770,047 (-)NCBI
Protein Sequences
Protein RefSeqs NP_000592 (Get FASTA)   NCBI Sequence Viewer  
  NP_001010931 (Get FASTA)   NCBI Sequence Viewer  
  NP_001010932 (Get FASTA)   NCBI Sequence Viewer  
  NP_001010933 (Get FASTA)   NCBI Sequence Viewer  
  NP_001010934 (Get FASTA)   NCBI Sequence Viewer  
  XP_047276249 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA35980 (Get FASTA)   NCBI Sequence Viewer  
  AAA52648 (Get FASTA)   NCBI Sequence Viewer  
  AAA52649 (Get FASTA)   NCBI Sequence Viewer  
  AAA52650 (Get FASTA)   NCBI Sequence Viewer  
  AAA64239 (Get FASTA)   NCBI Sequence Viewer  
  AAA64297 (Get FASTA)   NCBI Sequence Viewer  
  AAC50539 (Get FASTA)   NCBI Sequence Viewer  
  AAC71655 (Get FASTA)   NCBI Sequence Viewer  
  AAG53459 (Get FASTA)   NCBI Sequence Viewer  
  AAH22308 (Get FASTA)   NCBI Sequence Viewer  
  AAH63485 (Get FASTA)   NCBI Sequence Viewer  
  AAI05798 (Get FASTA)   NCBI Sequence Viewer  
  AAI30285 (Get FASTA)   NCBI Sequence Viewer  
  AAI30287 (Get FASTA)   NCBI Sequence Viewer  
  AAO61091 (Get FASTA)   NCBI Sequence Viewer  
  ACX45437 (Get FASTA)   NCBI Sequence Viewer  
  ACX45438 (Get FASTA)   NCBI Sequence Viewer  
  BAA14348 (Get FASTA)   NCBI Sequence Viewer  
  BAD92137 (Get FASTA)   NCBI Sequence Viewer  
  BAF84363 (Get FASTA)   NCBI Sequence Viewer  
  CAA34387 (Get FASTA)   NCBI Sequence Viewer  
  CAA40802 (Get FASTA)   NCBI Sequence Viewer  
  CAD38058 (Get FASTA)   NCBI Sequence Viewer  
  EAL24189 (Get FASTA)   NCBI Sequence Viewer  
  EAW76992 (Get FASTA)   NCBI Sequence Viewer  
  EAW76993 (Get FASTA)   NCBI Sequence Viewer  
  P14210 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_001010932   ⟸   NM_001010932
- Peptide Label: isoform 3 preproprotein
- UniProtKB: P14210 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_000592   ⟸   NM_000601
- Peptide Label: isoform 1 preproprotein
- UniProtKB: Q9UDU6 (UniProtKB/Swiss-Prot),   P14210 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001010933   ⟸   NM_001010933
- Peptide Label: isoform 4 precursor
- UniProtKB: P14210 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001010931   ⟸   NM_001010931
- Peptide Label: isoform 2 precursor
- UniProtKB: P14210 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001010934   ⟸   NM_001010934
- Peptide Label: isoform 5 precursor
- UniProtKB: P14210 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000413829   ⟸   ENST00000423064
RefSeq Acc Id: ENSP00000494355   ⟸   ENST00000465234
RefSeq Acc Id: ENSP00000396307   ⟸   ENST00000412881
RefSeq Acc Id: ENSP00000408270   ⟸   ENST00000453411
RefSeq Acc Id: ENSP00000391238   ⟸   ENST00000457544
RefSeq Acc Id: ENSP00000389854   ⟸   ENST00000444829
RefSeq Acc Id: ENSP00000346164   ⟸   ENST00000354224
RefSeq Acc Id: ENSP00000496217   ⟸   ENST00000643024
RefSeq Acc Id: ENSP00000222390   ⟸   ENST00000222390
RefSeq Acc Id: ENSP00000388592   ⟸   ENST00000421558
RefSeq Acc Id: XP_047276249   ⟸   XM_047420293
- Peptide Label: isoform X1
Protein Domains
Apple   Kringle   PAN   Peptidase S1

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P14210-F1-model_v2 AlphaFold P14210 1-728 view protein structure

Promoters
RGD ID:6805762
Promoter ID:HG_KWN:58346
Type:Non-CpG
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:HeLa_S3
Transcripts:ENST00000354224,   ENST00000394769,   NM_001010931,   NM_001010932,   NM_001010933,   OTTHUMT00000253315,   OTTHUMT00000337135,   OTTHUMT00000337170,   OTTHUMT00000337171,   OTTHUMT00000337172
Position:
Human AssemblyChrPosition (strand)Source
Build 36781,236,911 - 81,237,411 (-)MPROMDB
RGD ID:7210933
Promoter ID:EPDNEW_H11213
Type:initiation region
Name:HGF_1
Description:hepatocyte growth factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H11214  
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,770,047 - 81,770,107EPDNEW
RGD ID:7210937
Promoter ID:EPDNEW_H11214
Type:initiation region
Name:HGF_2
Description:hepatocyte growth factor
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Alternative Promoters:null; see alsoEPDNEW_H11213  
Experiment Methods:Single-end sequencing.; Paired-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38781,770,435 - 81,770,495EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:4893 AgrOrtholog
COSMIC HGF COSMIC
Ensembl Genes ENSG00000019991 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000222390 ENTREZGENE
  ENSP00000222390.5 UniProtKB/Swiss-Prot
  ENSP00000346164.6 UniProtKB/TrEMBL
  ENSP00000388592.1 UniProtKB/TrEMBL
  ENSP00000389854 ENTREZGENE
  ENSP00000389854.2 UniProtKB/Swiss-Prot
  ENSP00000391238 ENTREZGENE
  ENSP00000391238.2 UniProtKB/Swiss-Prot
  ENSP00000396307.1 UniProtKB/TrEMBL
  ENSP00000408270 ENTREZGENE
  ENSP00000408270.1 UniProtKB/Swiss-Prot
  ENSP00000413829 ENTREZGENE
  ENSP00000413829.2 UniProtKB/Swiss-Prot
  ENSP00000494355.1 UniProtKB/TrEMBL
  ENSP00000496217.1 UniProtKB/TrEMBL
Ensembl Transcript ENST00000222390 ENTREZGENE
  ENST00000222390.11 UniProtKB/Swiss-Prot
  ENST00000354224.10 UniProtKB/TrEMBL
  ENST00000412881.5 UniProtKB/TrEMBL
  ENST00000421558.1 UniProtKB/TrEMBL
  ENST00000423064 ENTREZGENE
  ENST00000423064.7 UniProtKB/Swiss-Prot
  ENST00000444829 ENTREZGENE
  ENST00000444829.7 UniProtKB/Swiss-Prot
  ENST00000453411 ENTREZGENE
  ENST00000453411.6 UniProtKB/Swiss-Prot
  ENST00000457544 ENTREZGENE
  ENST00000457544.7 UniProtKB/Swiss-Prot
  ENST00000465234.2 UniProtKB/TrEMBL
  ENST00000643024.1 UniProtKB/TrEMBL
Gene3D-CATH 2.40.10.10 UniProtKB/Swiss-Prot
  2.40.20.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Hepatocyte Growth Factor UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000019991 GTEx
HGNC ID HGNC:4893 ENTREZGENE
Human Proteome Map HGF Human Proteome Map
InterPro Hepatocyte_GF UniProtKB/Swiss-Prot
  HGF-like UniProtKB/Swiss-Prot
  Kringle UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kringle-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kringle_CS UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Kringle_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Pan_app UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Peptidase_S1_PA UniProtKB/Swiss-Prot
  Peptidase_S1_PA_chymotrypsin UniProtKB/Swiss-Prot
  Peptidase_S1A UniProtKB/Swiss-Prot
  Trypsin_dom UniProtKB/Swiss-Prot
KEGG Report hsa:3082 UniProtKB/Swiss-Prot
NCBI Gene 3082 ENTREZGENE
OMIM 142409 OMIM
  608265 OMIM
PANTHER KRINGLE DOMAIN-CONTAINING PROTEIN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PLASMINOGEN-RELATED UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Kringle UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAN_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Trypsin UniProtKB/Swiss-Prot
PharmGKB PA29269 PharmGKB
PIRSF Hepatocyte_GF UniProtKB/Swiss-Prot
  HGF_MST1 UniProtKB/Swiss-Prot
PRINTS CHYMOTRYPSIN UniProtKB/Swiss-Prot
  KRINGLE UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE KRINGLE_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  KRINGLE_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PAN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  TRYPSIN_DOM UniProtKB/Swiss-Prot
SMART PAN_AP UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SM00130 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Tryp_SPc UniProtKB/Swiss-Prot
Superfamily-SCOP Hairpin loop containing domain-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  SSF50494 UniProtKB/Swiss-Prot
  SSF57440 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A2R8YEI1_HUMAN UniProtKB/TrEMBL
  C9JDP4_HUMAN UniProtKB/TrEMBL
  C9JS80_HUMAN UniProtKB/TrEMBL
  C9WSJ3_HUMAN UniProtKB/TrEMBL
  C9WSJ4_HUMAN UniProtKB/TrEMBL
  HGF_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q9UDU6 ENTREZGENE
UniProt Secondary A1L3U6 UniProtKB/Swiss-Prot
  Q02935 UniProtKB/Swiss-Prot
  Q13494 UniProtKB/Swiss-Prot
  Q14519 UniProtKB/Swiss-Prot
  Q3KRB2 UniProtKB/Swiss-Prot
  Q8TCE2 UniProtKB/Swiss-Prot
  Q9BYL9 UniProtKB/Swiss-Prot
  Q9BYM0 UniProtKB/Swiss-Prot
  Q9UDU6 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-04-05 HGF  hepatocyte growth factor  DFNB39  deafness, autosomal recessive 39  Data Merged 737654 PROVISIONAL
2016-02-10 HGF  hepatocyte growth factor    hepatocyte growth factor (hepapoietin A; scatter factor)  Symbol and/or name change 5135510 APPROVED