BAD (BCL2 associated agonist of cell death) - Rat Genome Database
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Gene: BAD (BCL2 associated agonist of cell death) Homo sapiens
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Symbol: BAD
Name: BCL2 associated agonist of cell death
RGD ID: 735541
HGNC Page HGNC
Description: Exhibits cysteine-type endopeptidase activator activity involved in apoptotic process; phospholipid binding activity; and protein kinase binding activity. Involved in several processes, including apoptotic signaling pathway; cellular response to mechanical stimulus; and positive regulation of cysteine-type endopeptidase activity. Localizes to cytosol and mitochondrial outer membrane. Implicated in endometrial cancer; lung non-small cell carcinoma; and pancreatic cancer. Biomarker of several diseases, including Alzheimer's disease; bone disease (multiple); carcinoma (multiple); macular degeneration; and prostate disease (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: BBC2; bcl-2 associated death agonist; bcl-2-binding component 6; bcl-2-like protein 8; BCL-X/BCL-2 binding protein; bcl-XL/Bcl-2-associated death promoter; bcl2 antagonist of cell death; BCL2-antagonist of cell death; BCL2-associated agonist of cell death; BCL2-binding component 6; BCL2-binding protein; bcl2-L-8; BCL2L8
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1164,269,830 - 64,284,704 (-)EnsemblGRCh38hg38GRCh38
GRCh381164,269,828 - 64,284,704 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371164,037,300 - 64,052,176 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361163,793,878 - 63,808,740 (-)NCBINCBI36hg18NCBI36
Build 341163,793,877 - 63,808,740NCBI
Celera1161,364,184 - 61,379,075 (-)NCBI
Cytogenetic Map11q13.1NCBI
HuRef1160,365,093 - 60,379,900 (-)NCBIHuRef
CHM1_11163,920,295 - 63,935,173 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-alpha-tocopherol  (ISO)
(+)-epicatechin-3-O-gallate  (EXP)
(-)-Arctigenin  (EXP)
(S)-nicotine  (EXP,ISO)
1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane  (ISO)
1,3-Dinitropyrene  (ISO)
1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine  (ISO)
1-nitropyrene  (ISO)
17alpha-ethynylestradiol  (ISO)
17beta-estradiol  (EXP,ISO)
1H-pyrazole  (ISO)
2,2',4,4'-Tetrabromodiphenyl ether  (EXP)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2-methoxy-17beta-estradiol  (EXP)
2-naphthylamine  (EXP)
3,3',5-triiodo-L-thyronine  (EXP,ISO)
3,3'-diindolylmethane  (EXP)
3,4-methylenedioxymethamphetamine  (EXP,ISO)
3-methylcholanthrene  (ISO)
3-nitropropanoic acid  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one  (EXP)
4-hydroxynon-2-enal  (EXP)
4-nonylphenol  (ISO)
5-azacytidine  (ISO)
5-fluorouracil  (ISO)
9,10-anthraquinone  (EXP)
acetochlor  (EXP)
acetylsalicylic acid  (EXP)
acrolein  (EXP,ISO)
AH23848  (EXP)
aldehydo-D-glucose  (ISO)
all-trans-retinoic acid  (EXP)
alloxan  (ISO)
alvocidib  (EXP)
ammonium chloride  (ISO)
amphetamine  (ISO)
anthocyanin  (ISO)
anthra[1,9-cd]pyrazol-6(2H)-one  (EXP)
aprepitant  (EXP)
arachidonic acid  (EXP)
arjunolic acid  (ISO)
arsenite(3-)  (ISO)
arsenous acid  (EXP,ISO)
azadirachtin A  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP)
Benzo[a]pyrene-7,8-diol  (EXP)
benzo[b]fluoranthene  (ISO)
bis(2-chloroethyl) sulfide  (EXP)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
butanal  (EXP)
cadmium dichloride  (EXP,ISO)
cadmium sulfide  (EXP)
calciol  (EXP)
calcium atom  (ISO)
calcium(0)  (ISO)
capsaicin  (EXP)
carbon monoxide  (ISO)
carbon nanotube  (EXP,ISO)
carnosic acid  (EXP)
chlorpyrifos  (EXP)
chromium(6+)  (ISO)
ciglitazone  (ISO)
cisplatin  (EXP)
clonidine  (EXP)
clonidine (amino form)  (EXP)
clonidine (imino form)  (EXP)
cocaine  (ISO)
coenzyme Q10  (ISO)
copper atom  (EXP,ISO)
copper(0)  (EXP,ISO)
cordycepin  (EXP)
coumarin  (EXP)
curcumin  (EXP,ISO)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
D-glucose  (ISO)
D-mannitol  (ISO)
dehydroepiandrosterone  (ISO)
deoxynivalenol  (ISO)
dexamethasone  (ISO)
diallyl trisulfide  (EXP)
diarsenic trioxide  (EXP,ISO)
dibenzoylmethane  (EXP)
dibutyl phthalate  (ISO)
dicrotophos  (EXP)
diethanolamine  (ISO)
diethylstilbestrol  (ISO)
dimethylarsinic acid  (ISO)
diosmin  (ISO)
dioxygen  (EXP,ISO)
doxorubicin  (EXP,ISO)
doxycycline  (ISO)
ellagic acid  (EXP)
endosulfan  (ISO)
entinostat  (ISO)
erlotinib hydrochloride  (EXP)
ethanol  (ISO)
ethyl methanesulfonate  (EXP)
eugenol  (ISO)
flufenamic acid  (EXP)
fluoxetine  (ISO)
flutamide  (ISO)
folic acid  (ISO)
folpet  (ISO)
fulvestrant  (ISO)
furosemide  (ISO)
Fusarenone X  (ISO)
gamma-aminobutyric acid  (ISO)
genistein  (ISO)
ginsenoside Rg1  (ISO)
glucose  (ISO)
gold atom  (EXP)
gold(0)  (EXP)
graphite  (EXP)
hexadecanoic acid  (EXP)
hydralazine  (EXP)
hydrogen peroxide  (EXP,ISO)
hydroquinone  (EXP)
indometacin  (EXP)
iron atom  (EXP)
iron(0)  (EXP)
isoflurane  (ISO)
juglone  (EXP)
ketoconazole  (ISO)
L-ascorbic acid  (EXP,ISO)
lead diacetate  (ISO)
lipopolysaccharide  (ISO)
LY294002  (EXP,ISO)
maneb  (EXP)
melamine  (EXP)
melatonin  (EXP,ISO)
mercury atom  (EXP)
mercury dichloride  (ISO)
mercury(0)  (EXP)
metformin  (EXP)
methoxychlor  (ISO)
methyl methanesulfonate  (EXP)
methylglyoxal  (EXP)
methylmercury chloride  (EXP,ISO)
microcystin-LR  (EXP)
mifepristone  (ISO)
mitomycin C  (EXP)
MK-2206  (ISO)
monodansylcadaverine  (EXP)
N-(4-aminobutyl)-5-chloronaphthalene-2-sulfonamide  (EXP)
N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide  (ISO)
N-acetyl-L-cysteine  (EXP,ISO)
N-acetylsphingosine  (EXP)
N-ethyl-N-nitrosourea  (ISO)
N-methyl-4-phenylpyridinium  (EXP,ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (EXP,ISO)
N-methyl-N-nitrosourea  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
naringin  (ISO)
nickel dichloride  (ISO)
niclosamide  (EXP)
nicotine  (EXP,ISO)
norfloxacin  (EXP)
Obacunone  (EXP)
obeticholic acid  (EXP)
ochratoxin A  (EXP,ISO)
okadaic acid  (EXP)
omacetaxine mepesuccinate  (EXP)
oxaliplatin  (ISO)
oxybenzone  (ISO)
p-menthan-3-ol  (EXP)
paclitaxel  (EXP)
paracetamol  (EXP)
paraquat  (EXP,ISO)
PD 168393  (EXP)
pentachlorophenol  (ISO)
peroxynitrous acid  (EXP)
phenobarbital  (ISO)
phenylephrine  (EXP)
phorbol 13-acetate 12-myristate  (EXP)
pirinixic acid  (EXP,ISO)
PK-11195  (ISO)
plumbagin  (ISO)
potassium dichromate  (ISO)
Pranoprofen  (EXP)
pregnenolone 16alpha-carbonitrile  (ISO)
progesterone  (ISO)
propylparaben  (EXP)
pterostilbene  (ISO)
PX-866  (EXP)
quercetin  (EXP,ISO)
raloxifene  (EXP)
reactive oxygen species  (EXP)
resveratrol  (EXP,ISO)
rotenone  (EXP,ISO)
rottlerin  (ISO)
ruthenium atom  (EXP)
S-nitroso-N-acetyl-D-penicillamine  (ISO)
Salvianolic acid A  (ISO)
sildenafil citrate  (EXP)
simvastatin  (EXP,ISO)
sirolimus  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
sodium fluoride  (EXP)
sorafenib  (EXP,ISO)
spironolactone  (ISO)
stilbenoid  (EXP)
streptozocin  (ISO)
sulforaphane  (EXP)
sulindac  (EXP)
sulindac sulfide  (EXP)
tacrolimus hydrate  (EXP,ISO)
tamoxifen  (EXP)
taurine  (ISO)
tauroursodeoxycholic acid  (EXP,ISO)
tert-butyl hydroperoxide  (EXP,ISO)
testosterone  (ISO)
tetrachloromethane  (ISO)
tetrahydropalmatine  (EXP)
thapsigargin  (EXP)
thioacetamide  (ISO)
Thiotepa  (EXP)
thyroxine  (EXP)
tigecycline  (ISO)
Tiron  (EXP)
titanium dioxide  (EXP)
tomelukast  (ISO)
triamcinolone acetonide  (ISO)
tributylstannane  (ISO)
trichloroethene  (EXP,ISO)
trimethyltin  (ISO)
tunicamycin  (EXP)
valproic acid  (EXP)
vemurafenib  (EXP)
vitamin E  (ISO)
vorinostat  (EXP)
withaferin A  (EXP)
wortmannin  (EXP,ISO)
Y-27632  (EXP)
zoledronic acid  (EXP)
zolmitriptan  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
activation of cysteine-type endopeptidase activity  (IBA,IDA)
activation of cysteine-type endopeptidase activity involved in apoptotic process  (ISO,ISS)
ADP metabolic process  (ISO,ISS)
apoptotic process  (IDA,IEA,TAS)
apoptotic signaling pathway  (ISO)
ATP metabolic process  (ISO,ISS)
cell population proliferation  (ISO)
cellular response to chromate  (IEA,ISO)
cellular response to hypoxia  (IBA,IEP)
cellular response to lipid  (IEA,ISO)
cellular response to mechanical stimulus  (IEP)
cellular response to nicotine  (IDA)
cerebral cortex development  (IEA,ISO)
cytokine-mediated signaling pathway  (IEA,ISO)
extrinsic apoptotic signaling pathway  (IBA,IMP)
extrinsic apoptotic signaling pathway in absence of ligand  (IEA,ISO)
extrinsic apoptotic signaling pathway via death domain receptors  (IEA,ISO)
glucose catabolic process  (IEA,ISO)
glucose homeostasis  (ISO,ISS)
intrinsic apoptotic signaling pathway  (IBA,IMP)
intrinsic apoptotic signaling pathway in response to DNA damage  (IEA,ISO)
pore complex assembly  (IDA)
positive regulation of apoptotic process  (IDA,IMP,ISO)
positive regulation of apoptotic process by virus  (IEA,ISO)
positive regulation of autophagy  (TAS)
positive regulation of B cell differentiation  (IEA,ISO)
positive regulation of cysteine-type endopeptidase activity involved in apoptotic process  (IDA)
positive regulation of epithelial cell proliferation  (IMP)
positive regulation of glucokinase activity  (ISO,ISS)
positive regulation of granulosa cell apoptotic process  (IEA,ISO)
positive regulation of insulin secretion  (ISO,ISS)
positive regulation of insulin secretion involved in cellular response to glucose stimulus  (IEA,ISO)
positive regulation of intrinsic apoptotic signaling pathway  (TAS)
positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress  (IEA,ISO)
positive regulation of mitochondrial membrane potential  (ISO,ISS)
positive regulation of neuron death  (IEA,ISO)
positive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway  (TAS)
positive regulation of proteolysis  (IDA)
positive regulation of release of cytochrome c from mitochondria  (IMP)
positive regulation of T cell differentiation  (IEA,ISO)
positive regulation of type B pancreatic cell development  (ISO,ISS)
protein insertion into mitochondrial membrane involved in apoptotic signaling pathway  (TAS)
regulation of apoptotic process  (ISO)
regulation of cysteine-type endopeptidase activity involved in apoptotic process  (ISO)
regulation of mitochondrial membrane permeability  (IBA,IMP)
release of cytochrome c from mitochondria  (IBA,ISO)
response to amino acid  (IEA,ISO)
response to benzene  (IEA,ISO)
response to calcium ion  (IEA,ISO)
response to drug  (IEA,ISO)
response to estradiol  (IEA,ISO)
response to ethanol  (IEA,ISO)
response to glucocorticoid  (IEA,ISO)
response to glucose  (IEA,ISO)
response to hormone  (ISO)
response to hydrogen peroxide  (IEA,ISO)
response to hypoxia  (ISO)
response to oleic acid  (IEA,ISO)
response to organic cyclic compound  (ISO)
response to organic substance  (ISO)
response to progesterone  (IEA,ISO)
response to testosterone  (IEA,ISO)
spermatogenesis  (IEA,ISO)
suppression by virus of host apoptotic process  (IEA,ISO)
type B pancreatic cell proliferation  (ISO,ISS)

Cellular Component
cytoplasm  (ISO)
cytosol  (IBA,IDA,ISO,TAS)
mitochondrial outer membrane  (IDA,TAS)
mitochondrion  (IBA,IDA,ISO)

References

References - curated
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Additional References at PubMed
PMID:7834748   PMID:8929531   PMID:8929532   PMID:9130713   PMID:9305851   PMID:9369453   PMID:9381178   PMID:9388232   PMID:9389483   PMID:9463381   PMID:9651683   PMID:9824152  
PMID:9878060   PMID:9973195   PMID:10195903   PMID:10358075   PMID:10381646   PMID:10407019   PMID:10521512   PMID:10558990   PMID:10579309   PMID:10611223   PMID:10620799   PMID:10811615  
PMID:10837486   PMID:10837489   PMID:10880354   PMID:10949025   PMID:10949026   PMID:11077446   PMID:11206074   PMID:11278245   PMID:11410287   PMID:11483855   PMID:11494146   PMID:11500364  
PMID:11526496   PMID:11544290   PMID:11583631   PMID:11689886   PMID:11697890   PMID:11717309   PMID:11739707   PMID:11839683   PMID:11878929   PMID:11908866   PMID:11994280   PMID:12084714  
PMID:12087097   PMID:12115603   PMID:12137781   PMID:12239175   PMID:12376548   PMID:12477932   PMID:12657644   PMID:12754297   PMID:12787561   PMID:12842996   PMID:12897128   PMID:12931191  
PMID:12954615   PMID:12965220   PMID:14702039   PMID:14767529   PMID:14967141   PMID:15033904   PMID:15078178   PMID:15131699   PMID:15183529   PMID:15226424   PMID:15231831   PMID:15280438  
PMID:15489334   PMID:15574335   PMID:15694340   PMID:15705582   PMID:15721256   PMID:15722337   PMID:15731037   PMID:15751984   PMID:15767261   PMID:15849194   PMID:15901741   PMID:15978696  
PMID:15990872   PMID:15998799   PMID:16148027   PMID:16189514   PMID:16297499   PMID:16403219   PMID:16413544   PMID:16445909   PMID:16484005   PMID:16509771   PMID:16603546   PMID:16697956  
PMID:16710454   PMID:16728406   PMID:16767165   PMID:16785131   PMID:16843435   PMID:16847055   PMID:16908594   PMID:16932738   PMID:16949642   PMID:16978419   PMID:17011751   PMID:17110373  
PMID:17270021   PMID:17274640   PMID:17287851   PMID:17289999   PMID:17389761   PMID:17393317   PMID:17404594   PMID:17420275   PMID:17438366   PMID:17446862   PMID:17457084   PMID:17474147  
PMID:17485524   PMID:17499381   PMID:17541305   PMID:17544220   PMID:17557568   PMID:17670745   PMID:17696955   PMID:17696989   PMID:17900801   PMID:17927446   PMID:17979178   PMID:18006502  
PMID:18029348   PMID:18165867   PMID:18246127   PMID:18276761   PMID:18309324   PMID:18387192   PMID:18391004   PMID:18402774   PMID:18402937   PMID:18420586   PMID:18449891   PMID:18508762  
PMID:18508827   PMID:18568448   PMID:18593990   PMID:18628207   PMID:18636124   PMID:18651163   PMID:18651222   PMID:18676776   PMID:18775810   PMID:18798227   PMID:18832722   PMID:18852119  
PMID:18973553   PMID:19168699   PMID:19171933   PMID:19427857   PMID:19427863   PMID:19508210   PMID:19587239   PMID:19593445   PMID:19624871   PMID:19641507   PMID:19667065   PMID:19679565  
PMID:19730683   PMID:19773546   PMID:19882362   PMID:19895838   PMID:19913121   PMID:20005908   PMID:20012528   PMID:20043968   PMID:20179209   PMID:20339252   PMID:20596645   PMID:20603619  
PMID:20618440   PMID:20628086   PMID:20647330   PMID:20691103   PMID:20700721   PMID:20810912   PMID:20837658   PMID:20855536   PMID:20877624   PMID:20936779   PMID:21076048   PMID:21081150  
PMID:21187157   PMID:21302807   PMID:21317286   PMID:21419810   PMID:21444773   PMID:21674599   PMID:21849418   PMID:21873635   PMID:21900206   PMID:21988832   PMID:22000515   PMID:22006182  
PMID:22011203   PMID:22057915   PMID:22096607   PMID:22172950   PMID:22214866   PMID:22423221   PMID:22464442   PMID:22805310   PMID:22837380   PMID:23085457   PMID:23135712   PMID:23383273  
PMID:23397142   PMID:23547889   PMID:23794242   PMID:23811558   PMID:24008843   PMID:24038028   PMID:24040284   PMID:24247158   PMID:24255178   PMID:24344204   PMID:24421315   PMID:24614958  
PMID:24865460   PMID:24901052   PMID:24947039   PMID:25215949   PMID:25241761   PMID:25266655   PMID:25416956   PMID:25499972   PMID:25524600   PMID:25538080   PMID:25653146   PMID:25770209  
PMID:25872771   PMID:25907960   PMID:26063499   PMID:26186194   PMID:26234675   PMID:26264872   PMID:26467384   PMID:26496610   PMID:26506422   PMID:26581978   PMID:26590798   PMID:26668309  
PMID:26712345   PMID:26721202   PMID:26722503   PMID:26871637   PMID:26892230   PMID:26976600   PMID:27112371   PMID:27173435   PMID:27235542   PMID:27684187   PMID:27935851   PMID:28009301  
PMID:28081730   PMID:28423695   PMID:28486788   PMID:28514442   PMID:28518135   PMID:28569785   PMID:28611106   PMID:28611215   PMID:28620180   PMID:28641032   PMID:28645514   PMID:28753606  
PMID:28937296   PMID:29175327   PMID:29175460   PMID:29286138   PMID:29658076   PMID:29695560   PMID:29956797   PMID:29997244   PMID:30250224   PMID:30425242   PMID:30482844   PMID:30635657  
PMID:31003766   PMID:31467278   PMID:31509041   PMID:31515488   PMID:31906916   PMID:31980649   PMID:32296183   PMID:32473226   PMID:32814053  


Genomics

Comparative Map Data
BAD
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1164,269,830 - 64,284,704 (-)EnsemblGRCh38hg38GRCh38
GRCh381164,269,828 - 64,284,704 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371164,037,300 - 64,052,176 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361163,793,878 - 63,808,740 (-)NCBINCBI36hg18NCBI36
Build 341163,793,877 - 63,808,740NCBI
Celera1161,364,184 - 61,379,075 (-)NCBI
Cytogenetic Map11q13.1NCBI
HuRef1160,365,093 - 60,379,900 (-)NCBIHuRef
CHM1_11163,920,295 - 63,935,173 (-)NCBICHM1_1
Bad
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm39196,919,229 - 6,929,273 (+)NCBIGRCm39mm39
GRCm38196,941,861 - 6,951,905 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl196,941,861 - 6,951,899 (+)EnsemblGRCm38mm10GRCm38
MGSCv37197,016,345 - 7,026,383 (+)NCBIGRCm37mm9NCBIm37
MGSCv36197,008,899 - 7,018,937 (+)NCBImm8
Celera196,718,946 - 6,728,897 (+)NCBICelera
Cytogenetic Map19ANCBI
Bad
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.21204,133,502 - 204,142,829 (+)NCBI
Rnor_6.0 Ensembl1222,198,534 - 222,207,453 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_6.01222,198,516 - 222,207,459 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_5.01229,189,271 - 229,198,306 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41209,617,373 - 209,626,292 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11209,775,802 - 209,784,722NCBI
Celera1201,667,864 - 201,676,765 (+)NCBICelera
Cytogenetic Map1q43NCBI
Bad
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495542220,795,676 - 20,809,245 (+)EnsemblChiLan1.0
ChiLan1.0NW_00495542220,795,585 - 20,809,039 (+)NCBIChiLan1.0ChiLan1.0
BAD
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11162,971,808 - 62,986,304 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1162,971,808 - 62,986,257 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01159,626,981 - 59,641,824 (-)NCBIMhudiblu_PPA_v0panPan3
BAD
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl1852,781,921 - 52,791,405 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.11852,781,335 - 52,791,789 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Bad
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049365994,924,349 - 4,933,683 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
BAD
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl27,830,920 - 7,842,863 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.127,831,192 - 7,842,864 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.226,897,866 - 6,909,685 (+)NCBISscrofa10.2Sscrofa10.2susScr3
BAD
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.119,949,717 - 9,964,433 (+)NCBI
ChlSab1.1 Ensembl19,949,762 - 9,964,432 (+)Ensembl
Bad
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462476722,025,721 - 22,037,283 (+)NCBI

Position Markers
SHGC-64070  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371164,037,390 - 64,037,576UniSTSGRCh37
Build 361163,793,966 - 63,794,152RGDNCBI36
Celera1161,364,274 - 61,364,460RGD
Cytogenetic Map11q13.1UniSTS
HuRef1160,365,183 - 60,365,369UniSTS
TNG Radiation Hybrid Map1127949.0UniSTS
RH80521  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371164,037,326 - 64,037,573UniSTSGRCh37
Build 361163,793,902 - 63,794,149RGDNCBI36
Celera1161,364,210 - 61,364,457RGD
Cytogenetic Map11q13.1UniSTS
HuRef1160,365,119 - 60,365,366UniSTS
GeneMap99-GB4 RH Map11249.86UniSTS
RH80230  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371164,037,484 - 64,037,674UniSTSGRCh37
Build 361163,794,060 - 63,794,250RGDNCBI36
Celera1161,364,368 - 61,364,558RGD
Cytogenetic Map11q13.1UniSTS
HuRef1160,365,277 - 60,365,467UniSTS
RH27709  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371164,043,674 - 64,043,839UniSTSGRCh37
Build 361163,800,250 - 63,800,415RGDNCBI36
Celera1161,370,564 - 61,370,738RGD
Cytogenetic Map11q13.1UniSTS
HuRef1160,371,461 - 60,371,642UniSTS
PMC230316P4  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371164,037,549 - 64,037,809UniSTSGRCh37
Build 361163,794,125 - 63,794,385RGDNCBI36
Celera1161,364,433 - 61,364,693RGD
Cytogenetic Map11cen-q22.3UniSTS
Cytogenetic Map11q13.1UniSTS
HuRef1160,365,342 - 60,365,602UniSTS
D11S4747  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371164,043,651 - 64,043,835UniSTSGRCh37
Build 361163,800,227 - 63,800,411RGDNCBI36
Celera1161,370,541 - 61,370,734RGD
HuRef1160,371,438 - 60,371,638UniSTS
RH78541  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371164,037,556 - 64,037,689UniSTSGRCh37
Build 361163,794,132 - 63,794,265RGDNCBI36
Celera1161,364,440 - 61,364,573RGD
Cytogenetic Map11cen-q22.3UniSTS
Cytogenetic Map11q13.1UniSTS
HuRef1160,365,349 - 60,365,482UniSTS
GeneMap99-GB4 RH Map11238.55UniSTS
BAD_2670  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371164,037,205 - 64,037,842UniSTSGRCh37
Build 361163,793,781 - 63,794,418RGDNCBI36
Celera1161,364,089 - 61,364,726RGD
HuRef1160,364,998 - 60,365,635UniSTS
D8S2279  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map21q22.12UniSTS
Cytogenetic Map15q13UniSTS
Cytogenetic Map9q32UniSTS
Cytogenetic Map15q22.3UniSTS
Cytogenetic Map17p12UniSTS
Cytogenetic Map21q21.3UniSTS
Cytogenetic Map3p22-p21.3UniSTS
Cytogenetic Map1q21.1UniSTS
Cytogenetic Map2q24.2UniSTS
Cytogenetic Map17q24.2UniSTS
Cytogenetic Map1q32UniSTS
Cytogenetic Map3p25.3UniSTS
Cytogenetic Map20q13.3UniSTS
Cytogenetic Map2q31.1UniSTS
Cytogenetic Map1q21UniSTS
Cytogenetic Map3p14.1UniSTS
Cytogenetic Map2q37.3UniSTS
Cytogenetic Map7p14.1UniSTS
Cytogenetic Map2q22.3UniSTS
Cytogenetic Map15q13.2UniSTS
Cytogenetic Map12q24.1UniSTS
Cytogenetic Map7p15.2UniSTS
Cytogenetic Map5q31.2UniSTS
Cytogenetic Map2p25.2UniSTS
Cytogenetic Map3p24.3UniSTS
Cytogenetic Map17q25.3UniSTS
Cytogenetic Map15q22.31UniSTS
Cytogenetic Map5q14UniSTS
Cytogenetic Map5q31UniSTS
Cytogenetic Map1p36.32UniSTS
Cytogenetic Map1q42.12UniSTS
Cytogenetic Map7q21.11UniSTS
Cytogenetic Map9q34.2UniSTS
Cytogenetic Map19q13.3UniSTS
Cytogenetic Map22q13.33UniSTS
Cytogenetic Map8q22.3UniSTS
Cytogenetic Map6p21.1-p12UniSTS
Cytogenetic Map1p36.13UniSTS
Cytogenetic Map7q36.3UniSTS
Cytogenetic Map2p25.1UniSTS
Cytogenetic Map7p21.3UniSTS
Cytogenetic Map4q12UniSTS
Cytogenetic Map22q11.22UniSTS
Cytogenetic Map11p13UniSTS
Cytogenetic Map1q12UniSTS
Cytogenetic Map8p23UniSTS
Cytogenetic Map11q13.2-q13.3UniSTS
Cytogenetic Map13q14.1-q14.3UniSTS
Cytogenetic Map3q22-q24UniSTS
Cytogenetic Map3q13.1-q13.2UniSTS
Cytogenetic Map16q24UniSTS
Cytogenetic Map5q23.3-q31.1UniSTS
Cytogenetic Map8p21.3UniSTS
Cytogenetic Map14q32.3UniSTS
Cytogenetic Map7q11.23UniSTS
Cytogenetic Map7q32UniSTS
Cytogenetic Map14q32.33UniSTS
Cytogenetic Map19p13.2UniSTS
Cytogenetic Map9q34.3UniSTS
Cytogenetic Map1p32.3UniSTS
Cytogenetic Map17q11UniSTS
Cytogenetic Map17p13.1-p12UniSTS
Cytogenetic Map18q21.33UniSTS
Cytogenetic Map19p13.12UniSTS
Cytogenetic Map5q14.1UniSTS
Cytogenetic Map14q24.3UniSTS
Cytogenetic Map1q21-q23UniSTS
Cytogenetic MapXp11.23UniSTS
Cytogenetic Map4q21.1UniSTS
Cytogenetic Map12q13.13UniSTS
Cytogenetic Map14q23.3UniSTS
Cytogenetic Map17p12-p11.2UniSTS
Cytogenetic Map6p21.1UniSTS
Cytogenetic Map1q24UniSTS
Cytogenetic Map1q43UniSTS
Cytogenetic Map9q34.13UniSTS
Cytogenetic Map19q13.4UniSTS
Cytogenetic Map2q32UniSTS
Cytogenetic MapXp22.2UniSTS
Cytogenetic Map19p13.11UniSTS
Cytogenetic Map2q33UniSTS
Cytogenetic Map10p13UniSTS
Cytogenetic Map2q11.2UniSTS
Cytogenetic Map3q27UniSTS
Cytogenetic Map17q25.1UniSTS
Cytogenetic Map4p16.1UniSTS
Cytogenetic Map14q22.3UniSTS
Cytogenetic Map10q23-q24UniSTS
Cytogenetic Map2q37.1UniSTS
Cytogenetic Map17q12UniSTS
Cytogenetic Map14q31-q32UniSTS
Cytogenetic Map5p15.33UniSTS
Cytogenetic Map1q23.2UniSTS
Cytogenetic Map16q24.3UniSTS
Cytogenetic Map4p14UniSTS
Cytogenetic Map2q32.3UniSTS
Cytogenetic Map15q21.1UniSTS
Cytogenetic Map4q32.2UniSTS
Cytogenetic Map10q23UniSTS
Cytogenetic Map5q14.2UniSTS
Cytogenetic Map4q32.1UniSTS
Cytogenetic Map1q25.1UniSTS
Cytogenetic Map11q14.1UniSTS
Cytogenetic Map4p16.3UniSTS
Cytogenetic Map1p34.2UniSTS
Cytogenetic Map11q23.1UniSTS
Cytogenetic Map3p21.1UniSTS
Cytogenetic Map16q22.2UniSTS
Cytogenetic Map14q32.31UniSTS
Cytogenetic Map16q11.2UniSTS
Cytogenetic Map6q22UniSTS
Cytogenetic Map10p15.3UniSTS
Cytogenetic Map11q23UniSTS
Cytogenetic Map22q13.2UniSTS
Cytogenetic Map12q12UniSTS
Cytogenetic Map19q13.42UniSTS
Cytogenetic Map19q13.11UniSTS
Cytogenetic Map12q24.31UniSTS
Cytogenetic Map15q15UniSTS
Cytogenetic Map2q33.1UniSTS
Cytogenetic Map22q12.3UniSTS
Cytogenetic Map20q11UniSTS
Cytogenetic Map22q11.23UniSTS
Cytogenetic Map17q25UniSTS
Cytogenetic Map1p13.3UniSTS
Cytogenetic Map3p22.1UniSTS
Cytogenetic Map8q22.1UniSTS
Cytogenetic Map16q22.1UniSTS
Cytogenetic Map18p11.31UniSTS
Cytogenetic Map19p12UniSTS
Cytogenetic Map11q13.1UniSTS
Cytogenetic Map19p13.3UniSTS
Cytogenetic Map2p22.1UniSTS
Cytogenetic Map16p13.3UniSTS
Cytogenetic Map1p35.2UniSTS
Cytogenetic MapYp11.2UniSTS
Cytogenetic Map13q13.1UniSTS
Cytogenetic Map20q11.22UniSTS
Cytogenetic Map19q13.2UniSTS
Cytogenetic Map18q12UniSTS
Cytogenetic Map17q21.33UniSTS
Cytogenetic Map15q15.1UniSTS
Cytogenetic Map3q27.2UniSTS
Cytogenetic Map3q21.3UniSTS
Cytogenetic Map5p15.2UniSTS
Cytogenetic Map20q13.12UniSTS
Cytogenetic Map17q21UniSTS
Cytogenetic Map1q42UniSTS
Cytogenetic Map14q32.11UniSTS
Cytogenetic Map17q21.2-q21.3UniSTS
Cytogenetic Map5q32-q34UniSTS
Cytogenetic Map15q14UniSTS
Cytogenetic Map16q13UniSTS
Cytogenetic Map3q21.2UniSTS
Cytogenetic Map3p21.3UniSTS
Cytogenetic Map14q24.2UniSTS
Cytogenetic Map12q24.13UniSTS
Cytogenetic Map13q14.11UniSTS
Cytogenetic Map3q27.3UniSTS
Cytogenetic Map1q32.3UniSTS
Cytogenetic Map6p22.1UniSTS
Cytogenetic Map9q34.11UniSTS
Cytogenetic Map6q21UniSTS
Cytogenetic Map6q25.3UniSTS
Cytogenetic Map2p11.2UniSTS
Cytogenetic Map13q14.3UniSTS
Cytogenetic Map17q11.2UniSTS
Cytogenetic Map10p12UniSTS
Cytogenetic Map2q33.3UniSTS
Cytogenetic Map14q21.3UniSTS
Cytogenetic Map8p22-p21UniSTS
Cytogenetic Map18q11.2UniSTS
Cytogenetic Map2p15UniSTS
Cytogenetic Map17q22UniSTS
Cytogenetic Map12q21.33UniSTS
Cytogenetic Map20q13.32UniSTS
Cytogenetic Map1p34.1UniSTS
Cytogenetic Map10q26UniSTS
Cytogenetic Map8p23.1UniSTS
Cytogenetic Map19p13UniSTS
Cytogenetic Map7q21.13UniSTS
Cytogenetic Map7q31.1UniSTS
Cytogenetic Map1p33UniSTS
Cytogenetic Map21q22.3UniSTS
Cytogenetic Map1p35.1UniSTS
Cytogenetic Map22q12.2UniSTS
Cytogenetic Map9q22.3UniSTS
Cytogenetic Map8q13.1UniSTS
Cytogenetic Map3q25UniSTS
Cytogenetic Map1p36.33UniSTS
Cytogenetic Map20q13.33UniSTS
Cytogenetic Map1p31.3UniSTS
Cytogenetic Map14q31.1UniSTS
Cytogenetic Map22q13.1UniSTS
Cytogenetic Map12q13.2UniSTS
Cytogenetic Map22q13.31-q13.33UniSTS
Cytogenetic Map20q13.31UniSTS
Cytogenetic Map11p11.2UniSTS
Cytogenetic Map1q41UniSTS
Cytogenetic Map1p36.11UniSTS
Cytogenetic Map15q25.2UniSTS
Cytogenetic Map14q11.2UniSTS
Cytogenetic Map17q23.2UniSTS
Cytogenetic Map7q32.2UniSTS
Cytogenetic Map19q13.12UniSTS
Cytogenetic Map1q32.1UniSTS
Cytogenetic Map6q25.1UniSTS
Cytogenetic Map19q13.43UniSTS
Cytogenetic Map9p13.3UniSTS
Cytogenetic Map16p11.2UniSTS
Cytogenetic Map2p13.1UniSTS
Cytogenetic Map22q11.21UniSTS
Cytogenetic Map3q29UniSTS
Cytogenetic Map7p13UniSTS
Cytogenetic Map11q23.3UniSTS
Cytogenetic Map14q31-q32.1UniSTS
Cytogenetic Map1q42.11UniSTS
Cytogenetic Map4q35.1UniSTS
Cytogenetic Map2p23.3UniSTS
Cytogenetic Map2p13.3UniSTS
Cytogenetic MapXp11.3UniSTS
Cytogenetic Map2q11.2-q12.1UniSTS
Cytogenetic Map20q13.13UniSTS
Cytogenetic Map1p22UniSTS
Cytogenetic Map6q16.2UniSTS
Cytogenetic Map18q23UniSTS
Cytogenetic Map2q14UniSTS
Cytogenetic Map20p11.23-p11.21UniSTS
Cytogenetic Map16p12.2UniSTS
Cytogenetic Map8p11.23UniSTS
Cytogenetic Map19q13.1UniSTS
Cytogenetic Map19q13UniSTS
Cytogenetic Map8p11.21UniSTS
Cytogenetic Map12q14.3UniSTS
Cytogenetic MapXq26.3UniSTS
Cytogenetic Map8q24.11UniSTS
Cytogenetic Map10q23.1UniSTS
Cytogenetic Map1q44UniSTS
Cytogenetic Map9q22.33UniSTS
Cytogenetic Map3p21.31UniSTS
Cytogenetic Map17p13.2UniSTS
Cytogenetic Map9q21.32UniSTS
Cytogenetic Map7q34UniSTS
Cytogenetic Map9q33.3UniSTS
Cytogenetic Map1p36.1UniSTS
Cytogenetic Map20q12UniSTS
Cytogenetic Map4q21.23UniSTS
Cytogenetic Map5q13.2UniSTS
Cytogenetic Map22q12.1UniSTS
Cytogenetic Map5q31.1UniSTS
Cytogenetic Map2q21.3UniSTS
Cytogenetic Map7q21.2UniSTS
Cytogenetic Map17q22.2UniSTS
Cytogenetic Map17p13UniSTS
Cytogenetic Map12q24.11UniSTS
Cytogenetic Map18q21UniSTS
Cytogenetic Map10q11.1UniSTS
Cytogenetic Map22q11.2UniSTS
Cytogenetic Map19q12UniSTS
Cytogenetic Map7q34-q35UniSTS
Cytogenetic Map15q24.1UniSTS
Cytogenetic Map18p11.21UniSTS
Cytogenetic Map1q23.1UniSTS
Cytogenetic Map19q13.41UniSTS
Cytogenetic Map6p25.1-p23UniSTS
Cytogenetic Map11p15.4UniSTS
Cytogenetic Map10q22UniSTS
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Cytogenetic Map13q12.12UniSTS
Cytogenetic Map13q14.2UniSTS
Cytogenetic Map12qUniSTS
Cytogenetic Map1pUniSTS
Cytogenetic Map16pUniSTS
Cytogenetic Map15qUniSTS
Cytogenetic Map7qUniSTS
Cytogenetic Map2qUniSTS
Cytogenetic Map5q13.1UniSTS
Cytogenetic Map11p14.1UniSTS
Cytogenetic Map4q32UniSTS
Cytogenetic Map2p22UniSTS
Cytogenetic Map5q14.3UniSTS
Cytogenetic Map10p12.1UniSTS
Cytogenetic Map5q23.2UniSTS
Cytogenetic Map2p24.1UniSTS
Cytogenetic Map8q24.13UniSTS
Cytogenetic Map12p13.32UniSTS
Cytogenetic Map9p21.1UniSTS
Cytogenetic Map9q34.2-q34.3UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2228
Count of miRNA genes:751
Interacting mature miRNAs:873
Transcripts:ENST00000309032, ENST00000394531, ENST00000394532, ENST00000492141, ENST00000493798, ENST00000544271, ENST00000544785
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component
High
Medium 2429 2780 1701 600 1651 442 4212 1985 3703 410 1442 1606 171 1204 2647 4
Low 5 207 23 22 298 22 143 208 12 8 7 2 2 1 141 1
Below cutoff 1 2 1 1 14 1 7 2 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_004322 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_032989 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB451254 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB451378 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF021792 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF031523 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK023420 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK291863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK303051 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK309150 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AP001453 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW014069 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC001901 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC095431 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BE255791 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG435829 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BG748336 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BT006678 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471076 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR541935 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR541959 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U66879 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000309032   ⟹   ENSP00000309103
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1164,269,834 - 64,284,669 (-)Ensembl
RefSeq Acc Id: ENST00000394531   ⟹   ENSP00000378039
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1164,270,256 - 64,284,653 (-)Ensembl
RefSeq Acc Id: ENST00000394532   ⟹   ENSP00000378040
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1164,269,830 - 64,284,639 (-)Ensembl
RefSeq Acc Id: ENST00000492141   ⟹   ENSP00000439202
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1164,270,308 - 64,272,856 (-)Ensembl
RefSeq Acc Id: ENST00000493798   ⟹   ENSP00000438975
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1164,270,269 - 64,271,868 (-)Ensembl
RefSeq Acc Id: ENST00000544271
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1164,276,761 - 64,284,704 (-)Ensembl
RefSeq Acc Id: ENST00000544785   ⟹   ENSP00000440575
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1164,270,001 - 64,284,369 (-)Ensembl
RefSeq Acc Id: NM_004322   ⟹   NP_004313
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381164,269,828 - 64,284,704 (-)NCBI
GRCh371164,037,300 - 64,052,176 (-)ENTREZGENE
Build 361163,793,878 - 63,808,657 (-)NCBI Archive
HuRef1160,365,093 - 60,379,900 (-)ENTREZGENE
CHM1_11163,920,295 - 63,935,173 (-)NCBI
Sequence:
RefSeq Acc Id: NM_032989   ⟹   NP_116784
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381164,269,830 - 64,284,665 (-)NCBI
GRCh371164,037,300 - 64,052,176 (-)ENTREZGENE
Build 361163,793,878 - 63,808,740 (-)NCBI Archive
HuRef1160,365,093 - 60,379,900 (-)ENTREZGENE
CHM1_11163,920,295 - 63,935,173 (-)NCBI
Sequence:
Reference Sequences
RefSeq Acc Id: NP_116784   ⟸   NM_032989
- UniProtKB: Q92934 (UniProtKB/Swiss-Prot),   A0A024R562 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_004313   ⟸   NM_004322
- UniProtKB: Q92934 (UniProtKB/Swiss-Prot),   A0A024R562 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: ENSP00000309103   ⟸   ENST00000309032
RefSeq Acc Id: ENSP00000440575   ⟸   ENST00000544785
RefSeq Acc Id: ENSP00000439202   ⟸   ENST00000492141
RefSeq Acc Id: ENSP00000438975   ⟸   ENST00000493798
RefSeq Acc Id: ENSP00000378040   ⟸   ENST00000394532
RefSeq Acc Id: ENSP00000378039   ⟸   ENST00000394531

Promoters
RGD ID:6788509
Promoter ID:HG_KWN:13203
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   HeLa_S3,   K562,   Lymphoblastoid,   NB4
Transcripts:OTTHUMT00000259182
Position:
Human AssemblyChrPosition (strand)Source
Build 361163,795,621 - 63,796,722 (-)MPROMDB
RGD ID:6788507
Promoter ID:HG_KWN:13205
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:K562
Transcripts:ENST00000394531,   NM_004322,   NM_032989,   UC009YPK.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361163,808,481 - 63,808,981 (-)MPROMDB
RGD ID:6853324
Promoter ID:EP74487
Type:multiple initiation site
Name:HS_BAD
Description:BCL2-antagonist of cell death.
SO ACC ID:SO:0000170
Source:EPD (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Mammalian gene collection (MGC) full-length cDNA cloning
Position:
Human AssemblyChrPosition (strand)Source
Build 361163,808,739 - 63,808,799EPD
RGD ID:7220853
Promoter ID:EPDNEW_H16172
Type:initiation region
Name:BAD_1
Description:BCL2 associated agonist of cell death
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381164,284,654 - 64,284,714EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_001170726.1(GPR137):c.1143C>T (p.Asp381=) single nucleotide variant Malignant melanoma [RCV000069589] Chr11:64288659 [GRCh38]
Chr11:64056131 [GRCh37]
Chr11:63812707 [NCBI36]
Chr11:11q13.1
not provided
GRCh38/hg38 11q12.3-13.1(chr11:62893226-64335043)x1 copy number loss See cases [RCV000140879] Chr11:62893226..64335043 [GRCh38]
Chr11:62660698..64102515 [GRCh37]
Chr11:62417274..63859091 [NCBI36]
Chr11:11q12.3-13.1
likely pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470) copy number gain See cases [RCV000511729] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:230616-134938470)x3 copy number gain See cases [RCV000510881] Chr11:230616..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:198510-134934063)x3 copy number gain not provided [RCV000737348] Chr11:198510..134934063 [GRCh37]
Chr11:11p15.5-q25
pathogenic
GRCh37/hg19 11p15.5-q25(chr11:70864-134938470)x3 copy number gain not provided [RCV000749874] Chr11:70864..134938470 [GRCh37]
Chr11:11p15.5-q25
pathogenic
dup(11)(q13.1q13.1) duplication Ependymoma [RCV000785872] Chr11:63533279..65429676 [GRCh37]
Chr11:11q13.1
likely pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:936 AgrOrtholog
COSMIC BAD COSMIC
Ensembl Genes ENSG00000002330 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000309103 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000378039 UniProtKB/TrEMBL
  ENSP00000378040 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000438975 UniProtKB/TrEMBL
  ENSP00000439202 UniProtKB/TrEMBL
  ENSP00000440575 UniProtKB/TrEMBL
Ensembl Transcript ENST00000309032 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000394531 UniProtKB/TrEMBL
  ENST00000394532 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000492141 UniProtKB/TrEMBL
  ENST00000493798 UniProtKB/TrEMBL
  ENST00000544785 UniProtKB/TrEMBL
GTEx ENSG00000002330 GTEx
HGNC ID HGNC:936 ENTREZGENE
Human Proteome Map BAD Human Proteome Map
InterPro BAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:572 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
NCBI Gene 572 ENTREZGENE
OMIM 603167 OMIM
PANTHER PTHR28540 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam Bcl-2_BAD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA25236 PharmGKB
UniProt A0A024R562 ENTREZGENE, UniProtKB/TrEMBL
  A8MXU7_HUMAN UniProtKB/TrEMBL
  BAD_HUMAN UniProtKB/Swiss-Prot
  F5GYS3_HUMAN UniProtKB/TrEMBL
  F5H1R6_HUMAN UniProtKB/TrEMBL
  F5H3B1_HUMAN UniProtKB/TrEMBL
  Q92934 ENTREZGENE
UniProt Secondary O14803 UniProtKB/Swiss-Prot
  Q6FH21 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-12-01 BAD  BCL2 associated agonist of cell death    BCL2-associated agonist of cell death  Symbol and/or name change 5135510 APPROVED
2011-08-16 BAD  BCL2-associated agonist of cell death  BAD  BCL2-associated agonist of cell death  Symbol and/or name change 5135510 APPROVED