OLR1 (oxidized low density lipoprotein receptor 1) - Rat Genome Database

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Gene: OLR1 (oxidized low density lipoprotein receptor 1) Homo sapiens
Analyze
Symbol: OLR1
Name: oxidized low density lipoprotein receptor 1
RGD ID: 731042
HGNC Page HGNC:8133
Description: Enables identical protein binding activity. Predicted to be involved in several processes, including leukocyte cell-cell adhesion; lipoprotein metabolic process; and positive regulation of superoxide anion generation. Predicted to act upstream of or within vasoconstriction and vesicle-mediated transport. Located in nucleoplasm and plasma membrane. Part of receptor complex. Implicated in cerebral amyloid angiopathy; coronary artery disease; and myocardial infarction.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: C-type lectin domain family 8 member A; CLEC8A; hLOX-1; lectin-type oxidized LDL receptor 1; LOX1; LOXIN; ox LDL receptor 1; oxidised low density lipoprotein (lectin-like) receptor 1; oxidized low density lipoprotein (lectin-like) receptor 1; oxidized low-density lipoprotein receptor 1; oxidized low-density lipoprotein receptor 1, soluble form; SCARE1; scavenger receptor class E, member 1; SLOX1
RGD Orthologs
Mouse
Rat
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381210,158,301 - 10,176,266 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1210,158,301 - 10,172,138 (-)EnsemblGRCh38hg38GRCh38
GRCh371210,310,900 - 10,324,731 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361210,202,166 - 10,216,057 (-)NCBINCBI36Build 36hg18NCBI36
Build 341210,202,168 - 10,216,004NCBI
Celera1215,471,560 - 15,485,454 (-)NCBICelera
Cytogenetic Map12p13.2NCBI
HuRef1210,054,056 - 10,067,944 (-)NCBIHuRef
CHM1_11210,280,199 - 10,294,080 (-)NCBICHM1_1
T2T-CHM13v2.01210,045,018 - 10,062,993 (-)NCBIT2T-CHM13v2.0
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
(-)-epigallocatechin 3-gallate  (EXP)
1-naphthyl isothiocyanate  (ISO)
1-O-palmitoyl-2-O-(5-oxovaleryl)-sn-glycero-3-phosphocholine  (EXP)
17beta-estradiol  (EXP,ISO)
17beta-estradiol 3-benzoate  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2-acetyl-1-alkyl-sn-glycero-3-phosphocholine  (EXP)
2-palmitoylglycerol  (EXP)
2-tert-butylhydroquinone  (EXP)
4,4'-sulfonyldiphenol  (EXP)
4-\{[(5,5,8,8-tetramethyl-5,6,7,8-tetrahydronaphthalen-2-yl)carbonyl]amino\}benzoic acid  (EXP)
5-aza-2'-deoxycytidine  (EXP)
6-propyl-2-thiouracil  (ISO)
8'-apo-beta,psi-caroten-8'-al  (EXP)
9-cis-retinoic acid  (EXP)
acetamide  (ISO)
aflatoxin B1  (ISO)
aldehydo-D-glucose  (EXP)
aldosterone  (EXP)
all-trans-4-oxoretinoic acid  (EXP)
all-trans-4-oxoretinol  (EXP)
all-trans-retinoic acid  (EXP)
all-trans-retinol  (EXP)
amitrole  (ISO)
amlodipine  (EXP)
ammonium chloride  (ISO)
andrographolide  (EXP)
apocynin  (EXP)
aristolochic acids  (ISO)
arsenous acid  (EXP)
atrazine  (ISO)
Bardoxolone methyl  (EXP)
benzalkonium chloride  (ISO)
benzo[a]pyrene  (EXP)
beta-carotene  (EXP)
bisphenol A  (EXP,ISO)
butanal  (EXP)
C.I. Natural Red 20  (ISO)
C60 fullerene  (ISO)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
calcitriol  (EXP)
carbon nanotube  (ISO)
carvedilol  (ISO)
cholesterol  (ISO)
chromium atom  (EXP,ISO)
chromium(6+)  (EXP)
clofibrate  (ISO)
cobalt dichloride  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
crocidolite asbestos  (EXP,ISO)
Cuprizon  (ISO)
curcumin  (EXP)
cytarabine  (EXP)
D-glucose  (EXP)
dehydroepiandrosterone  (ISO)
demethoxycurcumin  (EXP)
desferrioxamine B  (EXP)
diarsenic trioxide  (EXP)
dichloroacetic acid  (ISO)
dioxygen  (ISO)
donepezil hydrochloride  (EXP)
doxorubicin  (EXP,ISO)
ergosterol  (ISO)
fluoranthene  (ISO)
furan  (ISO)
glucose  (EXP)
hydrogen peroxide  (ISO)
indometacin  (ISO)
isorhamnetin  (EXP)
L-ascorbic acid  (EXP)
lidocaine  (ISO)
lipopolysaccharide  (EXP)
metformin  (ISO)
methimazole  (ISO)
methyllycaconitine  (ISO)
mono(2-ethylhexyl) phthalate  (EXP)
N-acetyl-L-cysteine  (ISO)
nickel subsulfide  (ISO)
nicotinic acid  (ISO)
nifedipine  (EXP)
nitrofen  (ISO)
ozone  (ISO)
paracetamol  (ISO)
pentanal  (EXP)
phenethyl caffeate  (ISO)
phorbol 13-acetate 12-myristate  (EXP)
potassium chromate  (EXP)
pravastatin  (ISO)
progesterone  (ISO)
propanal  (EXP)
quercetin  (EXP,ISO)
razoxane  (ISO)
resveratrol  (EXP,ISO)
S-(1,2-dichlorovinyl)-L-cysteine  (EXP)
sarin  (EXP)
SB 203580  (ISO)
serpentine asbestos  (EXP)
Shikonin  (ISO)
silicon dioxide  (EXP,ISO)
silver atom  (EXP)
silver(0)  (EXP)
simvastatin  (ISO)
sirolimus  (EXP)
sodium arsenite  (EXP,ISO)
sodium fluoride  (ISO)
Soman  (ISO)
spironolactone  (EXP)
sulfadimethoxine  (ISO)
sulforaphane  (EXP,ISO)
Tanshinone I  (ISO)
telmisartan  (EXP)
testosterone  (ISO)
tetrachloromethane  (ISO)
titanium dioxide  (EXP,ISO)
triclosan  (EXP)
varenicline  (ISO)
zaragozic acid A  (ISO)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
# Reference Title Reference Citation
1. Genetic variation in lectin-like oxidized low-density lipoprotein receptor 1 (LOX1) gene and the risk of coronary artery disease. Chen Q, etal., Circulation. 2003 Jul 1;107(25):3146-51. Epub 2003 Jun 16.
2. GOAs Human GO annotations GOA_HUMAN data from the GO Consortium
3. LOX-1 inhibition in myocardial ischemia-reperfusion injury: modulation of MMP-1 and inflammation. Li D, etal., Am J Physiol Heart Circ Physiol 2002 Nov;283(5):H1795-801.
4. Oxidized low-density lipoprotein receptor LOX-1 and apoptosis in human atherosclerotic lesions. Li DY, etal., J Cardiovasc Pharmacol Ther. 2002 Jul;7(3):147-53.
5. Unique repetitive sequence and unexpected regulation of expression of rat endothelial receptor for oxidized low-density lipoprotein (LOX-1). Nagase M, etal., Biochem J 1998 Mar 15;330 ( Pt 3):1417-22.
6. An oxidized low-density lipoprotein receptor gene variant is inversely associated with the severity of coronary artery disease. Ohmori R, etal., Clin Cardiol. 2004 Nov;27(11):641-4.
7. OMIM Disease Annotation Pipeline OMIM Disease Annotation Pipeline
8. ClinVar Automated Import and Annotation Pipeline RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
9. Data Import for Chemical-Gene Interactions RGD automated import pipeline for gene-chemical interactions
10. A 3'-UTR polymorphism in the oxidized LDL receptor 1 gene increases Abeta40 load as cerebral amyloid angiopathy in Alzheimer's disease. Shi J, etal., Acta Neuropathol (Berl). 2006 Jan;111(1):15-20. Epub 2005 Nov 22.
11. Oxidized LDL receptor gene (OLR1) is associated with the risk of myocardial infarction. Tatsuguchi M, etal., Biochem Biophys Res Commun. 2003 Mar 28;303(1):247-50.
12. LOX-1, an oxidized low-density lipoprotein receptor, was upregulated in the kidneys of chronic renal failure rats. Ueno T, etal., Hypertens Res. 2003 Jan;26(1):117-22.
Additional References at PubMed
PMID:9052782   PMID:9693095   PMID:9703956   PMID:9763655   PMID:9828121   PMID:9837956   PMID:9933026   PMID:10085242   PMID:10325241   PMID:10377073   PMID:11034947   PMID:11196705  
PMID:11256994   PMID:11284714   PMID:11728449   PMID:11745369   PMID:11821063   PMID:11915516   PMID:11985903   PMID:12073608   PMID:12354387   PMID:12384789   PMID:12419941   PMID:12477932  
PMID:12504834   PMID:12566375   PMID:12637341   PMID:12646204   PMID:12807963   PMID:12829655   PMID:12857870   PMID:12878212   PMID:14684693   PMID:15000751   PMID:15001526   PMID:15060104  
PMID:15276231   PMID:15342556   PMID:15472120   PMID:15480893   PMID:15489334   PMID:15529384   PMID:15695803   PMID:15727724   PMID:15780115   PMID:15792802   PMID:15797645   PMID:15838273  
PMID:15855339   PMID:15860461   PMID:15935375   PMID:15939022   PMID:15976314   PMID:16013913   PMID:16061745   PMID:16146427   PMID:16173915   PMID:16188066   PMID:16251892   PMID:16285995  
PMID:16434026   PMID:16511086   PMID:16690797   PMID:16829343   PMID:17022953   PMID:17050011   PMID:17306253   PMID:17416594   PMID:17538005   PMID:17717293   PMID:17854420   PMID:17909223  
PMID:17923264   PMID:17963022   PMID:17992634   PMID:18053692   PMID:18054331   PMID:18173546   PMID:18191876   PMID:18191942   PMID:18220661   PMID:18367271   PMID:18384690   PMID:18388896  
PMID:18390905   PMID:18408244   PMID:18469066   PMID:18474940   PMID:18514661   PMID:18544637   PMID:18636435   PMID:18755461   PMID:18781352   PMID:18801483   PMID:18845619   PMID:18996102  
PMID:19035131   PMID:19080712   PMID:19104003   PMID:19150883   PMID:19203752   PMID:19218767   PMID:19247493   PMID:19252093   PMID:19272636   PMID:19279231   PMID:19322201   PMID:19342029  
PMID:19358829   PMID:19452449   PMID:19487339   PMID:19570417   PMID:19574336   PMID:19578796   PMID:19664054   PMID:19667111   PMID:19687346   PMID:19730000   PMID:19801851   PMID:19913121  
PMID:19929426   PMID:19930880   PMID:19948975   PMID:19961348   PMID:20009034   PMID:20023241   PMID:20136518   PMID:20146162   PMID:20181930   PMID:20203069   PMID:20379614   PMID:20485444  
PMID:20602615   PMID:20615707   PMID:20628086   PMID:20691427   PMID:20692795   PMID:21035571   PMID:21037509   PMID:21040737   PMID:21130456   PMID:21130457   PMID:21134342   PMID:21177197  
PMID:21257822   PMID:21383245   PMID:21467660   PMID:21624357   PMID:21637860   PMID:21679701   PMID:21698300   PMID:21723858   PMID:21775114   PMID:21817106   PMID:21865331   PMID:21873635  
PMID:21901421   PMID:21937834   PMID:22116101   PMID:22135361   PMID:22271373   PMID:22347434   PMID:22369967   PMID:22549450   PMID:22570368   PMID:22619487   PMID:22641216   PMID:22791762  
PMID:22797935   PMID:22863784   PMID:22891927   PMID:22905453   PMID:22956623   PMID:23021597   PMID:23054405   PMID:23073138   PMID:23134583   PMID:23230281   PMID:23233095   PMID:23237633  
PMID:23376485   PMID:23382219   PMID:23391848   PMID:23433938   PMID:23535804   PMID:23583401   PMID:23632121   PMID:23665840   PMID:23683938   PMID:23806684   PMID:23807658   PMID:23811604  
PMID:23821487   PMID:23950953   PMID:23979132   PMID:24064019   PMID:24101392   PMID:24113299   PMID:24480971   PMID:24518001   PMID:24615033   PMID:24661313   PMID:24743687   PMID:24776598  
PMID:24786389   PMID:24846140   PMID:24895597   PMID:24929820   PMID:25007999   PMID:25080882   PMID:25170920   PMID:25200690   PMID:25216847   PMID:25247304   PMID:25308333   PMID:25416967  
PMID:25463747   PMID:25501227   PMID:25566960   PMID:25697875   PMID:25746549   PMID:25904137   PMID:25982096   PMID:26185381   PMID:26296941   PMID:26305474   PMID:26495844   PMID:26510581  
PMID:26542080   PMID:26607724   PMID:26666837   PMID:26752047   PMID:26892134   PMID:26895376   PMID:26906623   PMID:26932825   PMID:27025681   PMID:27519944   PMID:27525284   PMID:27546362  
PMID:27840386   PMID:27967338   PMID:28084571   PMID:28345638   PMID:28407763   PMID:28442661   PMID:28511903   PMID:28514442   PMID:28535009   PMID:28657156   PMID:28785062   PMID:28844714  
PMID:28860004   PMID:28883612   PMID:28898769   PMID:28941610   PMID:28983628   PMID:29078142   PMID:29094051   PMID:29103984   PMID:29107109   PMID:29168159   PMID:29211299   PMID:29330254  
PMID:29393358   PMID:29407891   PMID:29448251   PMID:29462603   PMID:30442557   PMID:30483757   PMID:30553539   PMID:30639239   PMID:30639242   PMID:30664710   PMID:30718451   PMID:30799974  
PMID:30829585   PMID:30961517   PMID:31142080   PMID:31397763   PMID:31428922   PMID:31560077   PMID:31562393   PMID:31626762   PMID:31655342   PMID:31718700   PMID:31737129   PMID:31746382  
PMID:31746956   PMID:31772687   PMID:31782085   PMID:31871319   PMID:31928155   PMID:31954703   PMID:32003295   PMID:32019809   PMID:32072428   PMID:32101051   PMID:32182251   PMID:32253563  
PMID:32277394   PMID:32308114   PMID:32394286   PMID:32410835   PMID:32468600   PMID:32734736   PMID:33159784   PMID:33397691   PMID:33524863   PMID:33961781   PMID:33964218   PMID:34052311  
PMID:34497641   PMID:34611296   PMID:34616409   PMID:34688153   PMID:34936535   PMID:35053320   PMID:35449557   PMID:35914814   PMID:36264049   PMID:36517590   PMID:36536941   PMID:36647317  
PMID:36910399   PMID:37089448   PMID:37271250   PMID:37421287   PMID:37668684  


Genomics

Comparative Map Data
OLR1
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh381210,158,301 - 10,176,266 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p14 Ensembl1210,158,301 - 10,172,138 (-)EnsemblGRCh38hg38GRCh38
GRCh371210,310,900 - 10,324,731 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361210,202,166 - 10,216,057 (-)NCBINCBI36Build 36hg18NCBI36
Build 341210,202,168 - 10,216,004NCBI
Celera1215,471,560 - 15,485,454 (-)NCBICelera
Cytogenetic Map12p13.2NCBI
HuRef1210,054,056 - 10,067,944 (-)NCBIHuRef
CHM1_11210,280,199 - 10,294,080 (-)NCBICHM1_1
T2T-CHM13v2.01210,045,018 - 10,062,993 (-)NCBIT2T-CHM13v2.0
Olr1
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396129,456,113 - 129,484,312 (-)NCBIGRCm39GRCm39mm39
GRCm39 Ensembl6129,462,207 - 129,484,128 (-)EnsemblGRCm39 Ensembl
GRCm386129,479,150 - 129,507,350 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6129,485,244 - 129,507,165 (-)EnsemblGRCm38mm10GRCm38
MGSCv376129,435,265 - 129,457,183 (-)NCBIGRCm37MGSCv37mm9NCBIm37
MGSCv366129,450,945 - 129,472,847 (-)NCBIMGSCv36mm8
Celera6131,207,291 - 131,231,036 (-)NCBICelera
Cytogenetic Map6F3NCBI
cM Map663.35NCBI
Olr1
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCr84164,612,460 - 164,635,082 (-)NCBIGRCr8
mRatBN7.24162,926,436 - 162,949,057 (-)NCBImRatBN7.2mRatBN7.2
mRatBN7.2 Ensembl4162,926,439 - 162,948,523 (-)EnsemblmRatBN7.2 Ensembl
UTH_Rnor_SHR_Utx4169,161,255 - 169,183,343 (-)NCBIRnor_SHRUTH_Rnor_SHR_Utx
UTH_Rnor_SHRSP_BbbUtx_1.04164,944,216 - 164,966,299 (-)NCBIRnor_SHRSPUTH_Rnor_SHRSP_BbbUtx_1.0
UTH_Rnor_WKY_Bbb_1.04163,578,251 - 163,600,337 (-)NCBIRnor_WKYUTH_Rnor_WKY_Bbb_1.0
Rnor_6.04163,239,853 - 163,261,937 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4163,239,849 - 163,261,958 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04211,883,405 - 211,905,489 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44166,747,228 - 166,769,340 (-)NCBIRGSC3.4RGSC_v3.4rn4RGSC3.4
RGSC_v3.14166,992,163 - 167,014,276 (-)NCBI
Celera4151,610,779 - 151,632,854 (-)NCBICelera
Cytogenetic Map4q42NCBI
OLR1
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
NHGRI_mPanPan1-v21015,639,357 - 15,653,035 (-)NCBINHGRI_mPanPan1-v2
NHGRI_mPanPan11215,636,115 - 15,649,789 (-)NCBINHGRI_mPanPan1
Mhudiblu_PPA_v01210,196,712 - 10,210,432 (-)NCBIMhudiblu_PPA_v0Mhudiblu_PPA_v0panPan3
PanPan1.11210,447,353 - 10,461,071 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1210,445,202 - 10,461,071 (-)Ensemblpanpan1.1panPan2
OLR1
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.12735,828,852 - 35,838,748 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
CanFam3.1 Ensembl2735,828,029 - 35,838,754 (+)EnsemblCanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha2710,782,915 - 10,794,739 (-)NCBIDog10K_Boxer_Tasha
ROS_Cfam_1.02736,174,950 - 36,186,764 (+)NCBIROS_Cfam_1.0
ROS_Cfam_1.0 Ensembl2736,174,912 - 36,184,980 (+)EnsemblROS_Cfam_1.0 Ensembl
UMICH_Zoey_3.12736,063,115 - 36,073,432 (+)NCBIUMICH_Zoey_3.1
UNSW_CanFamBas_1.02736,085,141 - 36,097,142 (+)NCBIUNSW_CanFamBas_1.0
UU_Cfam_GSD_1.02710,304,638 - 10,316,443 (-)NCBIUU_Cfam_GSD_1.0
Olr1
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440494597,273,899 - 97,284,746 (+)NCBIHiC_Itri_2
SpeTri2.0 EnsemblNW_004936902409,704 - 416,401 (+)EnsemblSpeTri2.0SpeTri2.0 Ensembl
SpeTri2.0NW_004936902405,536 - 416,393 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
OLR1
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl561,799,286 - 61,810,624 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.1561,799,356 - 61,809,691 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.2564,580,096 - 64,590,442 (-)NCBISscrofa10.2Sscrofa10.2susScr3
OLR1
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.11110,033,708 - 10,048,332 (-)NCBIChlSab1.1ChlSab1.1chlSab2
ChlSab1.1 Ensembl1110,033,635 - 10,048,256 (-)EnsemblChlSab1.1ChlSab1.1 EnsemblchlSab2
Vero_WHO_p1.0NW_0236660892,109,569 - 2,124,272 (-)NCBIVero_WHO_p1.0Vero_WHO_p1.0
Olr1
(Heterocephalus glaber - naked mole-rat)
Naked Mole-Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla_female_1.0 EnsemblNW_00462475226,920,453 - 26,933,089 (-)EnsemblHetGla_female_1.0HetGla_female_1.0 EnsemblhetGla2
HetGla 1.0NW_00462475226,920,354 - 26,948,108 (-)NCBIHetGla_female_1.0HetGla 1.0hetGla2

Variants

.
Variants in OLR1
14 total Variants

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_002543.4(OLR1):c.501G>C (p.Lys167Asn) single nucleotide variant Myocardial infarction, susceptibility to [RCV001799590]|OLR1-related condition [RCV003974804] Chr12:10160849 [GRCh38]
Chr12:10313448 [GRCh37]
Chr12:12p13.2
risk factor|benign
NM_002543.4(OLR1):c.*188= single nucleotide variant Myocardial infarction, susceptibility to [RCV001799591] Chr12:10159692 [GRCh38]
Chr12:10312291 [GRCh37]
Chr12:12p13.2
risk factor
GRCh38/hg38 12p13.33-11.22(chr12:121055-28415184)x1 copy number loss See cases [RCV000052776] Chr12:121055..28415184 [GRCh38]
Chr12:282465..28568117 [GRCh37]
Chr12:100482..28459384 [NCBI36]
Chr12:12p13.33-11.22
pathogenic
GRCh38/hg38 12p13.33-12.1(chr12:80412-25470329)x3 copy number gain See cases [RCV000053662] Chr12:80412..25470329 [GRCh38]
Chr12:282465..25623263 [GRCh37]
Chr12:59839..25514530 [NCBI36]
Chr12:12p13.33-12.1
pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:212976-33926913)x4 copy number gain See cases [RCV000053666] Chr12:212976..33926913 [GRCh38]
Chr12:322142..34079848 [GRCh37]
Chr12:192403..33971115 [NCBI36]
Chr12:12p13.33-11.1
pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:77187-34380176)x3 copy number gain See cases [RCV000053660] Chr12:77187..34380176 [GRCh38]
Chr12:282465..34533111 [GRCh37]
Chr12:56614..34424378 [NCBI36]
Chr12:12p13.33-11.1
pathogenic
NM_002543.3(OLR1):c.587C>T (p.Ser196Phe) single nucleotide variant Malignant melanoma [RCV000069778] Chr12:10160440 [GRCh38]
Chr12:10313039 [GRCh37]
Chr12:10204306 [NCBI36]
Chr12:12p13.2
not provided
GRCh38/hg38 12p13.33-11.1(chr12:121255-34603274)x3 copy number gain See cases [RCV000136611] Chr12:121255..34603274 [GRCh38]
Chr12:282465..34756209 [GRCh37]
Chr12:100682..34647476 [NCBI36]
Chr12:12p13.33-11.1
pathogenic
GRCh38/hg38 12p13.33-12.3(chr12:2871741-14987348)x3 copy number gain See cases [RCV000137694] Chr12:2871741..14987348 [GRCh38]
Chr12:2980907..15140282 [GRCh37]
Chr12:2851168..15031549 [NCBI36]
Chr12:12p13.33-12.3
pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:121271-34603261)x3 copy number gain See cases [RCV000139052] Chr12:121271..34603261 [GRCh38]
Chr12:282465..34756196 [GRCh37]
Chr12:100698..34647463 [NCBI36]
Chr12:12p13.33-11.1
pathogenic
GRCh38/hg38 12p13.33-q24.33(chr12:121271-133196807)x3 copy number gain See cases [RCV000139555] Chr12:121271..133196807 [GRCh38]
Chr12:282465..133773393 [GRCh37]
Chr12:100698..132283466 [NCBI36]
Chr12:12p13.33-q24.33
pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:54427-34608071)x4 copy number gain See cases [RCV000139787] Chr12:54427..34608071 [GRCh38]
Chr12:282465..34761006 [GRCh37]
Chr12:33854..34652273 [NCBI36]
Chr12:12p13.33-11.1
pathogenic
GRCh38/hg38 12p13.33-12.2(chr12:1258274-20657577)x3 copy number gain See cases [RCV000141905] Chr12:1258274..20657577 [GRCh38]
Chr12:1367440..20810511 [GRCh37]
Chr12:1237701..20701778 [NCBI36]
Chr12:12p13.33-12.2
pathogenic
GRCh38/hg38 12p13.33-11.1(chr12:64620-34682902)x4 copy number gain See cases [RCV000142149] Chr12:64620..34682902 [GRCh38]
Chr12:173786..34835837 [GRCh37]
Chr12:44047..34727104 [NCBI36]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:148034-34178799)x4 copy number gain See cases [RCV000240164] Chr12:148034..34178799 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:1-133851895)x3 copy number gain See cases [RCV000258805] Chr12:1..133851895 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic|likely pathogenic
chr12:10074776-18800953 complex variant complex Breast ductal adenocarcinoma [RCV000207105] Chr12:10074776..18800953 [GRCh37]
Chr12:12p13.31-12.3
uncertain significance
GRCh37/hg19 12p13.33-11.1(chr12:89061-34178799)x3 copy number gain See cases [RCV000240487] Chr12:89061..34178799 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.33-q11(chr12:173786-37869301)x3 copy number gain See cases [RCV000449191] Chr12:173786..37869301 [GRCh37]
Chr12:12p13.33-q11
pathogenic
GRCh37/hg19 12p13.2(chr12:10183511-10373521)x3 copy number gain See cases [RCV000449122] Chr12:10183511..10373521 [GRCh37]
Chr12:12p13.2
uncertain significance
GRCh37/hg19 12p13.33-12.1(chr12:173786-25286865)x3 copy number gain See cases [RCV000449287] Chr12:173786..25286865 [GRCh37]
Chr12:12p13.33-12.1
pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:173786-34835837)x3 copy number gain See cases [RCV000447551] Chr12:173786..34835837 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.33-12.2(chr12:173786-20026080)x3 copy number gain See cases [RCV000446050] Chr12:173786..20026080 [GRCh37]
Chr12:12p13.33-12.2
pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:189578-34756150) copy number gain See cases [RCV000446017] Chr12:189578..34756150 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902)x3 copy number gain See cases [RCV000510482] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:173787-133777902) copy number gain See cases [RCV000511643] Chr12:173787..133777902 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:565369-34835837)x3 copy number gain See cases [RCV000511580] Chr12:565369..34835837 [GRCh37]
Chr12:12p13.33-11.1
likely pathogenic
GRCh37/hg19 12p13.33-13.2(chr12:173786-11677456)x3 copy number gain See cases [RCV000510853] Chr12:173786..11677456 [GRCh37]
Chr12:12p13.33-13.2
pathogenic
GRCh37/hg19 12p13.33-11.22(chr12:173786-28219229)x3 copy number gain See cases [RCV000510961] Chr12:173786..28219229 [GRCh37]
Chr12:12p13.33-11.22
pathogenic
NM_002543.4(OLR1):c.428C>T (p.Pro143Leu) single nucleotide variant Inborn genetic diseases [RCV003263038] Chr12:10160922 [GRCh38]
Chr12:10313521 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_002543.4(OLR1):c.317T>C (p.Ile106Thr) single nucleotide variant Inborn genetic diseases [RCV003253420] Chr12:10166819 [GRCh38]
Chr12:10319418 [GRCh37]
Chr12:12p13.2
uncertain significance
GRCh37/hg19 12p13.33-q11(chr12:173786-37869107)x3 copy number gain not provided [RCV000683480] Chr12:173786..37869107 [GRCh37]
Chr12:12p13.33-q11
pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:173786-34835837)x2,3 copy number gain not provided [RCV000683478] Chr12:173786..34835837 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:173786-34835837)x3 copy number gain not provided [RCV000683479] Chr12:173786..34835837 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:191619-133777645)x3 copy number gain not provided [RCV000750246] Chr12:191619..133777645 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-q24.33(chr12:621220-133779118)x3 copy number gain not provided [RCV000750253] Chr12:621220..133779118 [GRCh37]
Chr12:12p13.33-q24.33
pathogenic
GRCh37/hg19 12p13.33-11.21(chr12:191619-31733044)x3 copy number gain not provided [RCV000750245] Chr12:191619..31733044 [GRCh37]
Chr12:12p13.33-11.21
pathogenic
NM_002543.4(OLR1):c.565-73C>T single nucleotide variant not provided [RCV001611447] Chr12:10160535 [GRCh38]
Chr12:10313134 [GRCh37]
Chr12:12p13.2
benign
GRCh37/hg19 12p13.33-12.3(chr12:189216-15001420) copy number gain not provided [RCV000767817] Chr12:189216..15001420 [GRCh37]
Chr12:12p13.33-12.3
pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:173786-34496628)x3 copy number gain not provided [RCV000847209] Chr12:173786..34496628 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
NM_002543.4(OLR1):c.310G>A (p.Glu104Lys) single nucleotide variant Inborn genetic diseases [RCV003251281] Chr12:10166826 [GRCh38]
Chr12:10319425 [GRCh37]
Chr12:12p13.2
uncertain significance
GRCh37/hg19 12p13.33-q11(chr12:274676-37869301)x4 copy number gain not provided [RCV001006470] Chr12:274676..37869301 [GRCh37]
Chr12:12p13.33-q11
pathogenic
GRCh37/hg19 12p13.31-13.2(chr12:10049346-10322120)x3 copy number gain not provided [RCV002473879] Chr12:10049346..10322120 [GRCh37]
Chr12:12p13.31-13.2
uncertain significance
GRCh37/hg19 12p13.33-12.1(chr12:173786-25286865) copy number gain not specified [RCV002052955] Chr12:173786..25286865 [GRCh37]
Chr12:12p13.33-12.1
pathogenic
GRCh37/hg19 12p13.33-11.1(chr12:173786-34835837) copy number gain not specified [RCV002052957] Chr12:173786..34835837 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.33-q11(chr12:173786-37869301) copy number gain not specified [RCV002052958] Chr12:173786..37869301 [GRCh37]
Chr12:12p13.33-q11
pathogenic
NM_002543.4(OLR1):c.490A>G (p.Asn164Asp) single nucleotide variant Inborn genetic diseases [RCV002728155] Chr12:10160860 [GRCh38]
Chr12:10313459 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_002543.4(OLR1):c.341A>G (p.Asn114Ser) single nucleotide variant Inborn genetic diseases [RCV002952267] Chr12:10166795 [GRCh38]
Chr12:10319394 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_002543.4(OLR1):c.677A>G (p.His226Arg) single nucleotide variant Inborn genetic diseases [RCV002888272] Chr12:10160350 [GRCh38]
Chr12:10312949 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_002543.4(OLR1):c.44C>T (p.Pro15Leu) single nucleotide variant Inborn genetic diseases [RCV002798268] Chr12:10172034 [GRCh38]
Chr12:10324633 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_002543.4(OLR1):c.260C>T (p.Ala87Val) single nucleotide variant Inborn genetic diseases [RCV002723080] Chr12:10166876 [GRCh38]
Chr12:10319475 [GRCh37]
Chr12:12p13.2
uncertain significance
GRCh37/hg19 12p13.33-11.1(chr12:176047-34179852)x4 copy number gain Pallister-Killian syndrome [RCV003154827] Chr12:176047..34179852 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
NM_002543.4(OLR1):c.83A>G (p.Gln28Arg) single nucleotide variant Inborn genetic diseases [RCV003208652] Chr12:10169169 [GRCh38]
Chr12:10321768 [GRCh37]
Chr12:12p13.2
likely benign
Single allele duplication not provided [RCV003448692] Chr12:188053..34856694 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
NM_002543.4(OLR1):c.714C>T (p.Tyr238=) single nucleotide variant OLR1-related condition [RCV003938917]|not provided [RCV003396210] Chr12:10159988 [GRCh38]
Chr12:10312587 [GRCh37]
Chr12:12p13.2
likely benign
GRCh37/hg19 12p13.33-11.1(chr12:173786-34835641)x3 copy number gain not specified [RCV003986979] Chr12:173786..34835641 [GRCh37]
Chr12:12p13.33-11.1
pathogenic
GRCh37/hg19 12p13.2(chr12:10183315-10370767)x3 copy number gain not specified [RCV003986987] Chr12:10183315..10370767 [GRCh37]
Chr12:12p13.2
uncertain significance
NM_002543.4(OLR1):c.424+9A>G single nucleotide variant OLR1-related condition [RCV003909310] Chr12:10166703 [GRCh38]
Chr12:10319302 [GRCh37]
Chr12:12p13.2
likely benign
NM_002543.4(OLR1):c.582A>T (p.Ala194=) single nucleotide variant OLR1-related condition [RCV003946830] Chr12:10160445 [GRCh38]
Chr12:10313044 [GRCh37]
Chr12:12p13.2
likely benign
miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:2333
Count of miRNA genes:853
Interacting mature miRNAs:974
Transcripts:ENST00000309539, ENST00000339968, ENST00000432556, ENST00000536989, ENST00000538745, ENST00000538873, ENST00000539518, ENST00000543414, ENST00000543993, ENST00000544577, ENST00000545927
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.

Markers in Region
D12S1696  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371210,311,863 - 10,311,955UniSTSGRCh37
Build 361210,203,130 - 10,203,222RGDNCBI36
Celera1215,472,524 - 15,472,620RGD
Cytogenetic Map12p13.2-p12.3UniSTS
HuRef1210,055,021 - 10,055,117UniSTS
Marshfield Genetic Map1220.27UniSTS
Marshfield Genetic Map1220.27RGD
Genethon Genetic Map1221.8UniSTS
deCODE Assembly Map1224.83UniSTS
RH68316  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371210,312,234 - 10,312,427UniSTSGRCh37
Build 361210,203,501 - 10,203,694RGDNCBI36
Celera1215,472,899 - 15,473,092RGD
Cytogenetic Map12p13.2-p12.3UniSTS
HuRef1210,055,396 - 10,055,589UniSTS
GeneMap99-GB4 RH Map1258.21UniSTS
STS-N51624  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371210,311,038 - 10,311,181UniSTSGRCh37
Build 361210,202,305 - 10,202,448RGDNCBI36
Celera1215,471,699 - 15,471,842RGD
Cytogenetic Map12p13.2-p12.3UniSTS
HuRef1210,054,195 - 10,054,338UniSTS
GeneMap99-GB4 RH Map1258.21UniSTS


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 2
Medium 37 369 91 41 240 27 180 5 654 110 112 686 21 62 143 3
Low 594 1320 945 266 562 143 1207 163 2620 248 811 600 127 604 893 2 1
Below cutoff 1600 1250 642 279 809 258 2312 1694 427 46 471 253 24 493 1382

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_016743 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001172632 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001172633 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_002543 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047428907 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047428908 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_047428909 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054372134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054372135 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_054372136 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB010710 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AB102861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC024224 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC115676 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AF035776 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AH007081 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ131757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK292124 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK295409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK298040 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK308009 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK316353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL551100 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX429248 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX429256 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC022295 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC055085 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BP219342 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BQ028409 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA309323 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CB955704 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471094 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068266 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS443020 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ314885 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JA885104 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

RefSeq Acc Id: ENST00000309539   ⟹   ENSP00000309124
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1210,158,301 - 10,172,132 (-)Ensembl
RefSeq Acc Id: ENST00000339968   ⟹   ENSP00000340572
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1210,160,402 - 10,167,599 (-)Ensembl
RefSeq Acc Id: ENST00000432556   ⟹   ENSP00000405116
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1210,159,667 - 10,172,132 (-)Ensembl
RefSeq Acc Id: ENST00000536989
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1210,159,668 - 10,160,561 (-)Ensembl
RefSeq Acc Id: ENST00000538745   ⟹   ENSP00000438925
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1210,160,347 - 10,167,663 (-)Ensembl
RefSeq Acc Id: ENST00000538873   ⟹   ENSP00000438744
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1210,160,867 - 10,167,168 (-)Ensembl
RefSeq Acc Id: ENST00000539518   ⟹   ENSP00000442389
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1210,159,901 - 10,169,182 (-)Ensembl
RefSeq Acc Id: ENST00000543414   ⟹   ENSP00000444068
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1210,160,878 - 10,170,387 (-)Ensembl
RefSeq Acc Id: ENST00000543993   ⟹   ENSP00000445085
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1210,159,584 - 10,167,599 (-)Ensembl
RefSeq Acc Id: ENST00000544577   ⟹   ENSP00000444457
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1210,159,515 - 10,172,138 (-)Ensembl
RefSeq Acc Id: ENST00000545927   ⟹   ENSP00000439251
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p14 Ensembl1210,159,618 - 10,172,117 (-)Ensembl
RefSeq Acc Id: NM_001172632   ⟹   NP_001166103
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381210,158,301 - 10,172,132 (-)NCBI
GRCh371210,310,899 - 10,324,790 (-)ENTREZGENE
HuRef1210,054,056 - 10,067,944 (-)ENTREZGENE
CHM1_11210,280,199 - 10,294,080 (-)NCBI
T2T-CHM13v2.01210,045,018 - 10,058,858 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001172633   ⟹   NP_001166104
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381210,158,301 - 10,172,132 (-)NCBI
GRCh371210,310,899 - 10,324,790 (-)ENTREZGENE
HuRef1210,054,056 - 10,067,944 (-)ENTREZGENE
CHM1_11210,280,199 - 10,294,080 (-)NCBI
T2T-CHM13v2.01210,045,018 - 10,058,858 (-)NCBI
Sequence:
RefSeq Acc Id: NM_002543   ⟹   NP_002534
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381210,158,301 - 10,172,132 (-)NCBI
GRCh371210,310,899 - 10,324,790 (-)ENTREZGENE
Build 361210,202,166 - 10,216,057 (-)NCBI Archive
HuRef1210,054,056 - 10,067,944 (-)ENTREZGENE
CHM1_11210,280,199 - 10,294,080 (-)NCBI
T2T-CHM13v2.01210,045,018 - 10,058,858 (-)NCBI
Sequence:
RefSeq Acc Id: XM_047428907   ⟹   XP_047284863
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381210,158,301 - 10,176,266 (-)NCBI
RefSeq Acc Id: XM_047428908   ⟹   XP_047284864
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381210,160,353 - 10,172,132 (-)NCBI
RefSeq Acc Id: XM_047428909   ⟹   XP_047284865
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381210,158,301 - 10,172,132 (-)NCBI
RefSeq Acc Id: XM_054372134   ⟹   XP_054228109
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01210,045,018 - 10,062,993 (-)NCBI
RefSeq Acc Id: XM_054372135   ⟹   XP_054228110
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01210,047,074 - 10,058,858 (-)NCBI
RefSeq Acc Id: XM_054372136   ⟹   XP_054228111
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
T2T-CHM13v2.01210,045,018 - 10,058,858 (-)NCBI
Protein Sequences
Protein RefSeqs NP_001166103 (Get FASTA)   NCBI Sequence Viewer  
  NP_001166104 (Get FASTA)   NCBI Sequence Viewer  
  NP_002534 (Get FASTA)   NCBI Sequence Viewer  
  XP_047284863 (Get FASTA)   NCBI Sequence Viewer  
  XP_047284864 (Get FASTA)   NCBI Sequence Viewer  
  XP_047284865 (Get FASTA)   NCBI Sequence Viewer  
  XP_054228109 (Get FASTA)   NCBI Sequence Viewer  
  XP_054228110 (Get FASTA)   NCBI Sequence Viewer  
  XP_054228111 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAC82329 (Get FASTA)   NCBI Sequence Viewer  
  AAC97927 (Get FASTA)   NCBI Sequence Viewer  
  AAH22295 (Get FASTA)   NCBI Sequence Viewer  
  ABC40744 (Get FASTA)   NCBI Sequence Viewer  
  BAA24580 (Get FASTA)   NCBI Sequence Viewer  
  BAC81565 (Get FASTA)   NCBI Sequence Viewer  
  BAF84813 (Get FASTA)   NCBI Sequence Viewer  
  BAG58360 (Get FASTA)   NCBI Sequence Viewer  
  BAG60339 (Get FASTA)   NCBI Sequence Viewer  
  BAH14724 (Get FASTA)   NCBI Sequence Viewer  
  CAB38175 (Get FASTA)   NCBI Sequence Viewer  
  CAD36113 (Get FASTA)   NCBI Sequence Viewer  
  CAD36117 (Get FASTA)   NCBI Sequence Viewer  
  CAL68889 (Get FASTA)   NCBI Sequence Viewer  
  CCQ77677 (Get FASTA)   NCBI Sequence Viewer  
  EAW96156 (Get FASTA)   NCBI Sequence Viewer  
  EAW96157 (Get FASTA)   NCBI Sequence Viewer  
  EAW96158 (Get FASTA)   NCBI Sequence Viewer  
  EAW96159 (Get FASTA)   NCBI Sequence Viewer  
Ensembl Protein ENSP00000309124
  ENSP00000309124.3
  ENSP00000340572
  ENSP00000405116
  ENSP00000405116.2
  ENSP00000438744.1
  ENSP00000438925.2
  ENSP00000439251
  ENSP00000439251.1
  ENSP00000442389
  ENSP00000442389.1
  ENSP00000444068.1
  ENSP00000444457.1
  ENSP00000445085.1
GenBank Protein P78380 (Get FASTA)   NCBI Sequence Viewer  
RefSeq Acc Id: NP_001166103   ⟸   NM_001172632
- Peptide Label: isoform 2
- UniProtKB: F5GZH1 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001166104   ⟸   NM_001172633
- Peptide Label: isoform 3
- UniProtKB: P78380 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_002534   ⟸   NM_002543
- Peptide Label: isoform 1
- UniProtKB: Q2PP00 (UniProtKB/Swiss-Prot),   G3V1I4 (UniProtKB/Swiss-Prot),   B4DI48 (UniProtKB/Swiss-Prot),   A8K7V9 (UniProtKB/Swiss-Prot),   Q7Z484 (UniProtKB/Swiss-Prot),   P78380 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000445085   ⟸   ENST00000543993
RefSeq Acc Id: ENSP00000444068   ⟸   ENST00000543414
RefSeq Acc Id: ENSP00000444457   ⟸   ENST00000544577
RefSeq Acc Id: ENSP00000309124   ⟸   ENST00000309539
RefSeq Acc Id: ENSP00000439251   ⟸   ENST00000545927
RefSeq Acc Id: ENSP00000340572   ⟸   ENST00000339968
RefSeq Acc Id: ENSP00000438744   ⟸   ENST00000538873
RefSeq Acc Id: ENSP00000438925   ⟸   ENST00000538745
RefSeq Acc Id: ENSP00000405116   ⟸   ENST00000432556
RefSeq Acc Id: ENSP00000442389   ⟸   ENST00000539518
RefSeq Acc Id: XP_047284863   ⟸   XM_047428907
- Peptide Label: isoform X1
- UniProtKB: Q2PP00 (UniProtKB/Swiss-Prot),   P78380 (UniProtKB/Swiss-Prot),   G3V1I4 (UniProtKB/Swiss-Prot),   B4DI48 (UniProtKB/Swiss-Prot),   A8K7V9 (UniProtKB/Swiss-Prot),   Q7Z484 (UniProtKB/Swiss-Prot)
RefSeq Acc Id: XP_047284865   ⟸   XM_047428909
- Peptide Label: isoform X3
RefSeq Acc Id: XP_047284864   ⟸   XM_047428908
- Peptide Label: isoform X2
RefSeq Acc Id: XP_054228109   ⟸   XM_054372134
- Peptide Label: isoform X1
RefSeq Acc Id: XP_054228111   ⟸   XM_054372136
- Peptide Label: isoform X3
RefSeq Acc Id: XP_054228110   ⟸   XM_054372135
- Peptide Label: isoform X2
Protein Domains
C-type lectin

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P78380-F1-model_v2 AlphaFold P78380 1-273 view protein structure

Promoters
RGD ID:7223155
Promoter ID:EPDNEW_H17324
Type:initiation region
Name:OLR1_1
Description:oxidized low density lipoprotein receptor 1
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381210,172,132 - 10,172,192EPDNEW

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:8133 AgrOrtholog
COSMIC OLR1 COSMIC
Ensembl Genes ENSG00000173391 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Transcript ENST00000309539 ENTREZGENE
  ENST00000309539.8 UniProtKB/Swiss-Prot
  ENST00000339968 UniProtKB/TrEMBL
  ENST00000432556 ENTREZGENE
  ENST00000432556.6 UniProtKB/Swiss-Prot
  ENST00000538745.5 UniProtKB/TrEMBL
  ENST00000538873.1 UniProtKB/TrEMBL
  ENST00000539518 ENTREZGENE
  ENST00000539518.5 UniProtKB/TrEMBL
  ENST00000543414.1 UniProtKB/TrEMBL
  ENST00000543993.5 UniProtKB/TrEMBL
  ENST00000544577.5 UniProtKB/TrEMBL
  ENST00000545927 ENTREZGENE
  ENST00000545927.5 UniProtKB/Swiss-Prot
Gene3D-CATH 3.10.100.10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
GTEx ENSG00000173391 GTEx
HGNC ID HGNC:8133 ENTREZGENE
Human Proteome Map OLR1 Human Proteome Map
InterPro C-type_lectin-like UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  C-type_lectin-like/link_sf UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  CTDL_fold UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ly49_N UniProtKB/Swiss-Prot
  NKR-like_CTLD UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:4973 UniProtKB/Swiss-Prot
NCBI Gene 4973 ENTREZGENE
OMIM 602601 OMIM
PANTHER OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 UniProtKB/Swiss-Prot
  OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 UniProtKB/Swiss-Prot
  OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 UniProtKB/TrEMBL
  OXIDIZED LOW-DENSITY LIPOPROTEIN RECEPTOR 1 UniProtKB/TrEMBL
Pfam Lectin_C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Ly49 UniProtKB/Swiss-Prot
PharmGKB PA31920 PharmGKB
PROSITE C_TYPE_LECTIN_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
SMART CLECT UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Superfamily-SCOP SSF56436 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A8K7V9 ENTREZGENE
  B4DI48 ENTREZGENE
  B7ZAN8_HUMAN UniProtKB/TrEMBL
  F5GZH1 ENTREZGENE, UniProtKB/TrEMBL
  F5H001_HUMAN UniProtKB/TrEMBL
  F5H0N6_HUMAN UniProtKB/TrEMBL
  F5H3G7_HUMAN UniProtKB/TrEMBL
  F5H7N8_HUMAN UniProtKB/TrEMBL
  G3V1I4 ENTREZGENE
  J3QTI8_HUMAN UniProtKB/TrEMBL
  OLR1_HUMAN UniProtKB/Swiss-Prot, ENTREZGENE
  Q2PP00 ENTREZGENE
  Q7Z484 ENTREZGENE
UniProt Secondary A8K7V9 UniProtKB/Swiss-Prot
  B4DI48 UniProtKB/Swiss-Prot
  G3V1I4 UniProtKB/Swiss-Prot
  Q2PP00 UniProtKB/Swiss-Prot
  Q7Z484 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-14 OLR1  oxidized low density lipoprotein receptor 1    oxidized low density lipoprotein (lectin-like) receptor 1  Symbol and/or name change 5135510 APPROVED