IL18 Human (+)-taxifolin multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Fluvastatin promotes the reaction [taxifolin inhibits the reaction [bisphenol A results in increased expression of IL18 protein]] more ... CTD PMID:35465754 IL18 Human (1->4)-beta-D-glucan multiple interactions ISO Il18 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of IL18 mRNA CTD PMID:36331819 IL18 Human (4-oxo-3-\{[5-(trifluoromethyl)-1,3-benzothiazol-2-yl]methyl\}-3,4-dihydrophthalazin-1-yl)acetic acid multiple interactions ISO Il18 (Mus musculus) 6480464 zopolrestat inhibits the reaction [Antigens and Plant results in increased expression of IL18 mRNA] CTD PMID:21334316 IL18 Human (E)-cinnamyl alcohol increases expression EXP 6480464 cinnamyl alcohol results in increased expression of IL18 protein CTD PMID:23063874 IL18 Human (R)-carnitine increases expression ISO Il18 (Rattus norvegicus) 6480464 Carnitine results in increased expression of IL18 protein CTD PMID:25669660 IL18 Human (S)-nicotine multiple interactions EXP 6480464 CHRNA5 protein affects the reaction [Nicotine results in increased secretion of IL18 protein] CTD PMID:35131329 IL18 Human (S)-nicotine increases secretion EXP 6480464 Nicotine results in increased secretion of IL18 protein CTD PMID:35131329 IL18 Human (S)-ropivacaine increases expression EXP 6480464 Ropivacaine results in increased expression of IL18 protein CTD PMID:36858639 IL18 Human (S)-ropivacaine multiple interactions EXP 6480464 Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of IL18 protein] more ... CTD PMID:36858639 IL18 Human 1,2-dichloroethane decreases expression ISO Il18 (Mus musculus) 6480464 ethylene dichloride results in decreased expression of IL18 mRNA CTD PMID:28189721 and PMID:28960355 IL18 Human 1,2-dichloroethane multiple interactions ISO Il18 (Mus musculus) 6480464 [ethylene dichloride co-treated with Ethanol] results in increased expression of IL18 protein and allyl sulfide inhibits the reaction [[ethylene dichloride co-treated with Ethanol] results in increased expression of IL18 protein] CTD PMID:37150348 IL18 Human 1,2-dimethylhydrazine decreases expression ISO Il18 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in decreased expression of IL18 mRNA CTD PMID:22206623 IL18 Human 1,2-dimethylhydrazine multiple interactions ISO Il18 (Mus musculus) 6480464 [1 and 2-Dimethylhydrazine co-treated with Folic Acid] results in decreased expression of IL18 mRNA CTD PMID:22206623 IL18 Human 1,3-benzothiazole-2-thiol increases expression EXP 6480464 captax results in increased expression of IL18 protein CTD PMID:23063874 IL18 Human 1,4-phenylenediamine increases expression EXP 6480464 4-phenylenediamine results in increased expression of IL18 protein CTD PMID:23063874 and PMID:27585668 IL18 Human 1,4-phenylenediamine multiple interactions EXP 6480464 PRDM1 protein promotes the reaction [4-phenylenediamine results in increased expression of IL18 protein] CTD PMID:27585668 IL18 Human 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine multiple interactions ISO Il18 (Mus musculus) 6480464 Trimetazidine inhibits the reaction [Folic Acid results in increased expression of IL18 protein] CTD PMID:35191561 IL18 Human 1-chloro-2,4,6-trinitrobenzene multiple interactions EXP 6480464 CASP1 protein promotes the reaction [Picryl Chloride results in increased cleavage of IL18 protein] CTD PMID:17429439 IL18 Human 1-chloro-2,4,6-trinitrobenzene increases secretion ISO Il18 (Mus musculus) 6480464 Picryl Chloride results in increased secretion of IL18 protein CTD PMID:20381601 IL18 Human 1-chloro-2,4,6-trinitrobenzene increases expression ISO Il18 (Mus musculus) 6480464 Picryl Chloride results in increased expression of IL18 mRNA and Picryl Chloride results in increased expression of IL18 protein CTD PMID:15734285 more ... IL18 Human 1-chloro-2,4,6-trinitrobenzene multiple interactions ISO Il18 (Mus musculus) 6480464 Cyclosporine inhibits the reaction [Picryl Chloride results in increased expression of IL18 protein] more ... CTD PMID:16442096 and PMID:20381601 IL18 Human 1-chloro-2,4,6-trinitrobenzene increases cleavage EXP 6480464 Picryl Chloride results in increased cleavage of IL18 protein CTD PMID:17429439 IL18 Human 1-chloro-2,4-dinitrobenzene increases activity ISO Il18 (Mus musculus) 6480464 Dinitrochlorobenzene results in increased activity of IL18 protein CTD PMID:15840424 IL18 Human 1-chloro-2,4-dinitrobenzene multiple interactions EXP 6480464 PRDM1 protein promotes the reaction [Dinitrochlorobenzene results in increased expression of IL18 protein] CTD PMID:27585668 IL18 Human 1-chloro-2,4-dinitrobenzene increases expression EXP 6480464 Dinitrochlorobenzene results in increased expression of IL18 protein CTD PMID:23063874 more ... IL18 Human 1-chloro-2,4-dinitrobenzene increases expression ISO Il18 (Mus musculus) 6480464 Dinitrochlorobenzene results in increased expression of IL18 mRNA CTD PMID:11708898 IL18 Human 17alpha-ethynylestradiol decreases expression ISO Il18 (Rattus norvegicus) 6480464 Ethinyl Estradiol results in decreased expression of IL18 mRNA CTD PMID:12075121 IL18 Human 17alpha-ethynylestradiol increases expression ISO Il18 (Rattus norvegicus) 6480464 Ethinyl Estradiol results in increased expression of IL18 mRNA CTD PMID:15576828 and PMID:17351261 IL18 Human 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of IL18 mRNA CTD PMID:22574217 IL18 Human 17beta-estradiol decreases expression ISO Il18 (Rattus norvegicus) 6480464 Estradiol results in decreased expression of IL18 mRNA CTD PMID:35192832 IL18 Human 17beta-estradiol affects expression ISO Il18 (Rattus norvegicus) 6480464 Estradiol affects the expression of IL18 mRNA CTD PMID:32145629 IL18 Human 17beta-estradiol increases expression EXP 6480464 Estradiol results in increased expression of IL18 mRNA CTD PMID:23373633 and PMID:25878060 IL18 Human 17beta-estradiol decreases expression EXP 6480464 Estradiol results in decreased expression of IL18 mRNA CTD PMID:25878060 IL18 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression EXP 6480464 Tetrachlorodibenzodioxin results in decreased expression of IL18 mRNA CTD PMID:16039398 IL18 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Il18 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of IL18 mRNA CTD PMID:33387578 IL18 Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Il18 (Mus musculus) 6480464 KL protein inhibits the reaction [Tetrachlorodibenzodioxin promotes the reaction [lipopolysaccharide more ... CTD PMID:29885354 IL18 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Il18 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of IL18 mRNA CTD PMID:20959002 more ... IL18 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Il18 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of IL18 mRNA CTD PMID:12167310 and PMID:21570461 IL18 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Il18 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin affects the expression of IL18 mRNA CTD PMID:22298810 IL18 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression EXP 6480464 Tetrachlorodibenzodioxin affects the expression of IL18 mRNA CTD PMID:22298810 IL18 Human 2,4,6-trinitrobenzenesulfonic acid increases expression ISO Il18 (Mus musculus) 6480464 Trinitrobenzenesulfonic Acid results in increased expression of IL18 mRNA CTD PMID:15973123 IL18 Human 2,4,6-trinitrobenzenesulfonic acid multiple interactions ISO Il18 (Rattus norvegicus) 6480464 bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL18 protein] CTD PMID:30365937 IL18 Human 2,4,6-trinitrobenzenesulfonic acid increases expression ISO Il18 (Rattus norvegicus) 6480464 Trinitrobenzenesulfonic Acid results in increased expression of IL18 protein CTD PMID:30365937 IL18 Human 2,4-D multiple interactions ISO Il18 (Rattus norvegicus) 6480464 lycium barbarum polysaccharide inhibits the reaction [2 more ... CTD PMID:34464015 IL18 Human 2,4-D multiple interactions ISO Il18 (Mus musculus) 6480464 lycium barbarum polysaccharide inhibits the reaction [2 more ... CTD PMID:35099110 IL18 Human 2,4-D increases expression ISO Il18 (Mus musculus) 6480464 2 more ... CTD PMID:35099110 IL18 Human 2,4-D increases expression ISO Il18 (Rattus norvegicus) 6480464 2 more ... CTD PMID:34464015 IL18 Human 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Il18 (Mus musculus) 6480464 2 more ... CTD PMID:38648751 IL18 Human 2-amino-2-deoxy-D-galactopyranose increases expression ISO Il18 (Mus musculus) 6480464 Galactosamine results in increased expression of IL18 mRNA and Galactosamine results in increased expression of IL18 protein CTD PMID:20102673 IL18 Human 2-amino-2-deoxy-D-galactopyranose increases expression ISO Il18 (Rattus norvegicus) 6480464 Galactosamine results in increased expression of IL18 mRNA CTD PMID:22310181 IL18 Human 2-amino-2-deoxy-D-galactopyranose multiple interactions ISO Il18 (Rattus norvegicus) 6480464 mangiferin inhibits the reaction [Galactosamine results in increased expression of IL18 mRNA] CTD PMID:22310181 IL18 Human 2-amino-2-deoxy-D-galactopyranose multiple interactions ISO Il18 (Mus musculus) 6480464 [LEP gene mutant form results in increased susceptibility to Galactosamine] which results in increased expression of IL18 mRNA more ... CTD PMID:19913045 and PMID:20102673 IL18 Human 2-bromo-2-(bromomethyl)pentanedinitrile increases expression EXP 6480464 1 more ... CTD PMID:23063874 IL18 Human 2-hydroxypropanoic acid decreases expression EXP 6480464 Lactic Acid results in decreased expression of IL18 mRNA CTD PMID:30851411 IL18 Human 2-palmitoylglycerol increases expression EXP 6480464 2-palmitoylglycerol results in increased expression of IL18 mRNA CTD PMID:37199045 IL18 Human 3,3',4,4',5-pentachlorobiphenyl affects expression EXP 6480464 3 more ... CTD PMID:21703328 IL18 Human 3,3',5,5'-tetrabromobisphenol A decreases expression ISO Il18 (Rattus norvegicus) 6480464 tetrabromobisphenol A results in decreased expression of IL18 mRNA CTD PMID:28300664 IL18 Human 3-chloropropane-1,2-diol decreases expression ISO Il18 (Rattus norvegicus) 6480464 alpha-Chlorohydrin results in decreased expression of IL18 mRNA CTD PMID:28522335 IL18 Human 3-chloropropane-1,2-diol multiple interactions ISO Il18 (Mus musculus) 6480464 alpha-Chlorohydrin results in increased expression of and results in increased secretion of IL18 protein and ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased secretion of IL18 protein] CTD PMID:38373586 IL18 Human 3-chloropropane-1,2-diol multiple interactions ISO Il18 (Rattus norvegicus) 6480464 ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in increased secretion of IL18 protein] CTD PMID:38373586 IL18 Human 3-chloropropane-1,2-diol increases secretion ISO Il18 (Rattus norvegicus) 6480464 alpha-Chlorohydrin results in increased secretion of IL18 protein CTD PMID:38373586 IL18 Human 3-chloropropane-1,2-diol increases expression ISO Il18 (Mus musculus) 6480464 alpha-Chlorohydrin results in increased expression of IL-18 mRNA CTD PMID:33913518 IL18 Human 3-methyladenine multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [Patulin results in increased expression of IL18 protein] and 3-methyladenine promotes the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein] CTD PMID:30205151 and PMID:33217525 IL18 Human 3-methyladenine multiple interactions ISO Il18 (Rattus norvegicus) 6480464 3-methyladenine inhibits the reaction [sphingosine 1-phosphate results in increased expression of IL18 protein] CTD PMID:37169277 IL18 Human 3-methylcholanthrene increases expression EXP 6480464 Methylcholanthrene results in increased expression of IL18 mRNA CTD PMID:14993811 IL18 Human 3-Nitrobenzanthrone decreases expression EXP 6480464 3-nitrobenzanthrone results in decreased expression of IL18 mRNA CTD PMID:34036453 IL18 Human 3-phenylprop-2-enal increases expression EXP 6480464 cinnamaldehyde results in increased expression of IL18 mRNA and cinnamaldehyde results in increased expression of IL18 protein CTD PMID:23063874 and PMID:30806763 IL18 Human 3H-1,2-dithiole-3-thione decreases expression ISO Il18 (Rattus norvegicus) 6480464 1 and 2-dithiol-3-thione results in decreased expression of IL18 mRNA CTD PMID:19162173 IL18 Human 4,4'-diaminodiphenylmethane decreases expression ISO Il18 (Mus musculus) 6480464 4 and 4'-diaminodiphenylmethane results in decreased expression of IL18 mRNA CTD PMID:18648102 IL18 Human 4,4'-sulfonyldiphenol decreases methylation EXP 6480464 bisphenol S results in decreased methylation of IL18 gene CTD PMID:31601247 IL18 Human 4-(ethoxymethylene)-2-phenyloxazol-5-one increases expression EXP 6480464 Oxazolone results in increased expression of IL18 protein CTD PMID:23063874 IL18 Human 4-hydroxynon-2-enal decreases expression ISO Il18 (Mus musculus) 6480464 4-hydroxy-2-nonenal results in decreased expression of IL18 mRNA CTD PMID:19191707 IL18 Human 4-hydroxynon-2-enal decreases expression EXP 6480464 4-hydroxy-2-nonenal results in decreased expression of IL18 mRNA CTD PMID:12419474 IL18 Human 4-hydroxyphenyl retinamide decreases expression ISO Il18 (Mus musculus) 6480464 Fenretinide results in decreased expression of IL18 mRNA CTD PMID:28973697 IL18 Human 4-methylhistamine multiple interactions EXP 6480464 4-methylhistamine inhibits the reaction [IL18 protein results in decreased expression of IL10 protein] more ... CTD PMID:11752121 and PMID:12364868 IL18 Human 4-nitrobenzyl bromide increases expression EXP 6480464 4-nitrobenzyl bromide results in increased expression of IL18 protein CTD PMID:23063874 IL18 Human 4-phenylbutyric acid multiple interactions ISO Il18 (Rattus norvegicus) 6480464 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL18 protein] CTD PMID:37654027 IL18 Human 4-phenylbutyric acid multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [7 more ... CTD PMID:35297523 and PMID:36646296 IL18 Human 4-phenylbutyric acid multiple interactions ISO Il18 (Mus musculus) 6480464 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of IL18 mRNA] CTD PMID:30796460 IL18 Human 5-fluorouracil multiple interactions EXP 6480464 [Fluorouracil co-treated with Irinotecan] results in decreased expression of IL18 mRNA more ... CTD PMID:15162350 and PMID:16391804 IL18 Human 5-fluorouracil affects expression ISO Il18 (Mus musculus) 6480464 Fluorouracil affects the expression of IL18 mRNA CTD PMID:20421339 IL18 Human 6-propyl-2-thiouracil increases expression ISO Il18 (Rattus norvegicus) 6480464 Propylthiouracil results in increased expression of IL18 mRNA CTD PMID:37047793 IL18 Human 7,12-dimethyltetraphene multiple interactions ISO Il18 (Mus musculus) 6480464 dieckol inhibits the reaction [9 more ... CTD PMID:33347706 IL18 Human 7,12-dimethyltetraphene increases expression ISO Il18 (Mus musculus) 6480464 9 more ... CTD PMID:33347706 IL18 Human 8-Br-cAMP increases expression EXP 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of IL18 mRNA CTD PMID:22079614 IL18 Human 8-chloro-2'-deoxyguanosine increases expression ISO Il18 (Mus musculus) 6480464 8-chloro-2'-deoxyguanosine results in increased expression of IL18 mRNA CTD PMID:31066272 IL18 Human acetamide increases expression ISO Il18 (Rattus norvegicus) 6480464 acetamide results in increased expression of IL18 mRNA CTD PMID:31881176 IL18 Human acetic acid increases expression ISO Il18 (Rattus norvegicus) 6480464 Acetic Acid results in increased expression of IL18 protein CTD PMID:35595039 IL18 Human acetic acid multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Plant Extracts inhibits the reaction [Acetic Acid results in increased expression of IL18 protein] and Sulfasalazine inhibits the reaction [Acetic Acid results in increased expression of IL18 protein] CTD PMID:35595039 IL18 Human acetylsalicylic acid multiple interactions ISO Il18 (Mus musculus) 6480464 Aspirin inhibits the reaction [Acetaminophen results in increased expression of IL18 mRNA] CTD PMID:19164858 IL18 Human acetylsalicylic acid affects response to substance EXP 6480464 IL18 polymorphism affects the susceptibility to Aspirin CTD PMID:21692767 IL18 Human aconitine increases expression ISO Il18 (Rattus norvegicus) 6480464 Aconitine results in increased expression of IL18 protein CTD PMID:33236894 IL18 Human aconitine increases expression ISO Il18 (Mus musculus) 6480464 Aconitine results in increased expression of IL18 protein CTD PMID:33236894 IL18 Human aconitine multiple interactions ISO Il18 (Rattus norvegicus) 6480464 NLRP3 protein affects the reaction [Aconitine results in increased expression of IL18 protein] more ... CTD PMID:33236894 IL18 Human acrolein multiple interactions EXP 6480464 3-methyladenine promotes the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein] more ... CTD PMID:30205151 and PMID:36055550 IL18 Human acrolein increases expression EXP 6480464 Acrolein results in increased expression of IL18 protein CTD PMID:36055550 IL18 Human acrylamide increases expression ISO Il18 (Rattus norvegicus) 6480464 Acrylamide results in increased expression of IL18 mRNA and Acrylamide results in increased expression of IL18 protein CTD PMID:31073625 IL18 Human acrylamide increases expression ISO Il18 (Mus musculus) 6480464 Acrylamide results in increased expression of IL18 mRNA and Acrylamide results in increased expression of IL18 protein CTD PMID:31073625 and PMID:32014472 IL18 Human acrylamide multiple interactions ISO Il18 (Mus musculus) 6480464 N-(1 more ... CTD PMID:31073625 and PMID:32014472 IL18 Human aflatoxin B1 affects expression EXP 6480464 Aflatoxin B1 affects the expression of IL18 protein CTD PMID:20106945 IL18 Human aflatoxin B1 multiple interactions ISO Il18 (Mus musculus) 6480464 Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of IL18 mRNA] and Curcumin inhibits the reaction [Aflatoxin B1 results in increased secretion of IL18 protein] CTD PMID:35063475 IL18 Human aflatoxin B1 increases secretion ISO Il18 (Mus musculus) 6480464 Aflatoxin B1 results in increased secretion of IL18 protein CTD PMID:35063475 IL18 Human aflatoxin B1 increases expression ISO Il18 (Mus musculus) 6480464 Aflatoxin B1 results in increased expression of IL18 mRNA CTD PMID:35063475 IL18 Human aflatoxin B1 decreases expression ISO Il18 (Mus musculus) 6480464 Aflatoxin B1 results in decreased expression of IL18 mRNA CTD PMID:36603704 IL18 Human aflatoxin B1 decreases methylation EXP 6480464 Aflatoxin B1 results in decreased methylation of IL18 gene CTD PMID:27153756 IL18 Human aldehydo-D-glucose increases expression EXP 6480464 Glucose results in increased expression of IL18 mRNA and Glucose results in increased expression of IL18 protein CTD PMID:36066211 more ... IL18 Human aldehydo-D-glucose multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL18 protein and diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL18 protein] CTD PMID:35191607 IL18 Human aldehydo-D-glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased secretion of IL18 protein more ... CTD PMID:35607288 more ... IL18 Human aldehydo-D-glucose increases secretion EXP 6480464 Glucose results in increased secretion of IL18 protein CTD PMID:35607288 IL18 Human aldehydo-D-glucose increases expression ISO Il18 (Mus musculus) 6480464 Glucose results in increased expression of IL18 mRNA CTD PMID:34212273 IL18 Human aldehydo-D-glucose increases secretion ISO Il18 (Mus musculus) 6480464 Glucose results in increased secretion of IL18 protein CTD PMID:34212273 IL18 Human aldehydo-D-glucose multiple interactions ISO Il18 (Mus musculus) 6480464 GSDMD protein affects the reaction [Glucose results in increased secretion of IL18 protein] and Hirudins inhibits the reaction [Glucose results in increased secretion of IL18 protein] CTD PMID:34212273 IL18 Human aldosterone increases expression ISO Il18 (Rattus norvegicus) 6480464 Aldosterone results in increased expression of IL18 mRNA and Aldosterone results in increased expression of IL18 protein CTD PMID:18660453 IL18 Human aldosterone multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [cyclo(Trp-Asp-Pro-Val-Leu) binds to and results in decreased activity of EDNRA protein] inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] more ... CTD PMID:18660453 IL18 Human alendronic acid multiple interactions ISO Il18 (Mus musculus) 6480464 [Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide more ... CTD PMID:21430599 IL18 Human all-trans-retinoic acid affects expression ISO Il18 (Mus musculus) 6480464 Tretinoin affects the expression of IL18 mRNA CTD PMID:20421339 IL18 Human allopurinol multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Allopurinol inhibits the reaction [Fructose results in increased expression of IL18 protein] and Allopurinol inhibits the reaction [Streptozocin results in increased expression of IL18 protein] CTD PMID:22426011 and PMID:23647015 IL18 Human alpha-Zearalanol multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of IL18 mRNA CTD PMID:35163327 IL18 Human aluminium sulfate (anhydrous) increases expression EXP 6480464 aluminum sulfate results in increased expression of IL18 protein CTD PMID:16100009 IL18 Human amiodarone multiple interactions ISO Il18 (Mus musculus) 6480464 Amiodarone promotes the reaction [Dexamethasone results in decreased expression of IL18 mRNA] CTD PMID:25900201 IL18 Human ammonium chloride affects expression ISO Il18 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of IL18 mRNA CTD PMID:16483693 IL18 Human amphibole asbestos increases expression EXP 6480464 Asbestos and Amphibole results in increased expression of IL18 protein CTD PMID:20855422 IL18 Human amphibole asbestos increases expression ISO Il18 (Rattus norvegicus) 6480464 Asbestos and Amphibole results in increased expression of IL18 mRNA CTD PMID:27083413 IL18 Human ampicillin multiple interactions ISO Il18 (Mus musculus) 6480464 [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased secretion of IL18 protein] CTD PMID:35390362 IL18 Human anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions EXP 6480464 pyrazolanthrone inhibits the reaction [[Lipopolysaccharides co-treated with irinotecan] results in increased expression of and results in increased secretion of IL18 protein] CTD PMID:26431797 IL18 Human anthra[1,9-cd]pyrazol-6(2H)-one multiple interactions ISO Il18 (Mus musculus) 6480464 pyrazolanthrone inhibits the reaction [Benzo(a)pyrene results in increased secretion of IL18 protein] more ... CTD PMID:20381601 more ... IL18 Human anthranilic acid multiple interactions EXP 6480464 anthranilic acid analog inhibits the reaction [IL18 protein results in increased secretion of IFNG protein] CTD PMID:15799959 IL18 Human antirheumatic drug decreases expression EXP 6480464 Antirheumatic Agents results in decreased expression of IL18 mRNA CTD PMID:24449571 IL18 Human apocynin multiple interactions ISO Il18 (Mus musculus) 6480464 acetovanillone analog inhibits the reaction [manganese chloride results in increased expression of IL18 mRNA] CTD PMID:28539244 IL18 Human Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of IL18 mRNA CTD PMID:17851650 IL18 Human arsenite(3-) decreases expression EXP 6480464 arsenite results in decreased expression of IL18 mRNA CTD PMID:16085347 IL18 Human arsenite(3-) multiple interactions EXP 6480464 arsenite promotes the reaction [G3BP1 protein binds to IL18 mRNA] more ... CTD PMID:16085347 more ... IL18 Human arsenous acid increases expression EXP 6480464 Arsenic Trioxide results in increased expression of IL18 mRNA CTD PMID:36801614 IL18 Human arsenous acid increases secretion EXP 6480464 Arsenic Trioxide results in increased secretion of IL18 protein CTD PMID:35226250 IL18 Human arsenous acid increases secretion ISO Il18 (Mus musculus) 6480464 Arsenic Trioxide results in increased secretion of IL18 protein CTD PMID:35226250 IL18 Human arsenous acid multiple interactions EXP 6480464 IGF2BP2 protein promotes the reaction [Arsenic Trioxide results in increased secretion of IL18 protein] and METTL14 protein promotes the reaction [Arsenic Trioxide results in increased secretion of IL18 protein] CTD PMID:35226250 IL18 Human arsenous acid decreases expression ISO Il18 (Mus musculus) 6480464 Arsenic Trioxide results in decreased expression of IL18 CTD PMID:20693187 IL18 Human asperentin increases expression ISO Il18 (Mus musculus) 6480464 cladosporin results in increased expression of IL18 mRNA CTD PMID:19818335 IL18 Human atorvastatin calcium multiple interactions ISO Il18 (Mus musculus) 6480464 Atorvastatin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL18 protein] CTD PMID:37023836 IL18 Human ATP multiple interactions EXP 6480464 [Adenosine Triphosphate co-treated with K-12 lipopolysaccharide] results in increased secretion of IL18 protein more ... CTD PMID:17404311 more ... IL18 Human ATP multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein more ... CTD PMID:35962723 IL18 Human ATP increases secretion ISO Il18 (Mus musculus) 6480464 Adenosine Triphosphate results in increased secretion of IL18 protein CTD PMID:27311643 IL18 Human ATP multiple interactions ISO Il18 (Mus musculus) 6480464 3-(5-(2 more ... CTD PMID:26431797 more ... IL18 Human atrazine decreases expression EXP 6480464 Atrazine results in decreased expression of IL18 mRNA CTD PMID:22378314 IL18 Human aucubin multiple interactions ISO Il18 (Mus musculus) 6480464 aucubin inhibits the reaction [[Streptozocin co-treated with Dietary Fats] results in increased expression of IL18 protein] CTD PMID:35961541 IL18 Human aurantio-obtusin increases expression ISO Il18 (Mus musculus) 6480464 aurantio-obtusin results in increased expression of IL18 mRNA and aurantio-obtusin results in increased expression of IL18 protein CTD PMID:34718095 IL18 Human bellidifolin multiple interactions EXP 6480464 bellidifolin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased secretion of IL18 protein] CTD PMID:37127800 IL18 Human Belnacasan multiple interactions ISO Il18 (Mus musculus) 6480464 belnacasan inhibits the reaction [Toluene 2 and 4-Diisocyanate results in increased expression of IL18 protein] CTD PMID:31070765 IL18 Human Belnacasan multiple interactions EXP 6480464 belnacasan inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein] CTD PMID:30205151 IL18 Human benzalkonium chloride increases expression ISO Il18 (Mus musculus) 6480464 Benzalkonium Compounds results in increased expression of IL18 protein CTD PMID:30517752 IL18 Human benzalkonium chloride increases expression EXP 6480464 Benzalkonium Compounds results in increased expression of IL18 mRNA CTD PMID:30806763 IL18 Human benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of IL18 mRNA and Benzo(a)pyrene results in increased expression of IL18 protein CTD PMID:21632981 more ... IL18 Human benzo[a]pyrene increases secretion ISO Il18 (Mus musculus) 6480464 Benzo(a)pyrene results in increased secretion of IL18 protein CTD PMID:35777681 IL18 Human benzo[a]pyrene increases expression ISO Il18 (Rattus norvegicus) 6480464 Benzo(a)pyrene results in increased expression of IL18 mRNA CTD PMID:34999049 IL18 Human benzo[a]pyrene multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Benzo(a)pyrene co-treated with Dibutyl Phthalate] results in increased expression of IL18 mRNA more ... CTD PMID:34999049 and PMID:36592837 IL18 Human benzo[a]pyrene affects methylation EXP 6480464 Benzo(a)pyrene affects the methylation of IL18 promoter CTD PMID:27901495 IL18 Human benzo[a]pyrene decreases methylation EXP 6480464 Benzo(a)pyrene results in decreased methylation of IL18 5' UTR CTD PMID:27901495 IL18 Human benzo[a]pyrene multiple interactions EXP 6480464 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Benzo(a)pyrene] results in increased expression of IL18 protein and IGF1 protein inhibits the reaction [Benzo(a)pyrene results in increased expression of IL18 protein] CTD PMID:30726812 IL18 Human benzo[a]pyrene multiple interactions ISO Il18 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Benzo(a)pyrene results in increased secretion of IL18 protein] more ... CTD PMID:22228805 and PMID:35777681 IL18 Human benzo[a]pyrene diol epoxide I multiple interactions EXP 6480464 4-phenylbutyric acid inhibits the reaction [7 more ... CTD PMID:35297523 IL18 Human benzocaine increases activity ISO Il18 (Mus musculus) 6480464 Benzocaine results in increased activity of IL18 protein CTD PMID:15840424 IL18 Human benzylpenicillin increases expression EXP 6480464 Penicillin G results in increased expression of IL18 protein CTD PMID:23063874 IL18 Human Bergenin multiple interactions ISO Il18 (Rattus norvegicus) 6480464 bergenin inhibits the reaction [Trinitrobenzenesulfonic Acid results in increased expression of IL18 protein] CTD PMID:30365937 IL18 Human beryllium sulfate increases expression EXP 6480464 beryllium sulfate results in increased expression of IL18 mRNA and beryllium sulfate results in increased expression of IL18 protein CTD PMID:16100009 IL18 Human beta-cyclodextrin multiple interactions ISO Il18 (Mus musculus) 6480464 [myelin oligodendrocyte glycoprotein (35-55) co-treated with Freund's Adjuvant co-treated with Pertussis Toxin co-treated with betadex] results in increased expression of IL18 protein and lonidamine inhibits the reaction [[myelin oligodendrocyte glycoprotein (35-55) co-treated with Freund's Adjuvant co-treated with Pertussis Toxin co-treated with betadex] results in increased expression of IL18 protein] CTD PMID:36577999 IL18 Human bexarotene decreases expression ISO Il18 (Rattus norvegicus) 6480464 bexarotene results in decreased expression of IL18 mRNA CTD PMID:16648578 IL18 Human bezafibrate multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Bezafibrate inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 IL18 Human bilirubin IXalpha multiple interactions EXP 6480464 Bilirubin inhibits the reaction [IL18 protein results in decreased phosphorylation of AKT1 protein] and Bilirubin inhibits the reaction [IL18 protein results in increased expression of PTEN protein] CTD PMID:18215737 IL18 Human bilirubin IXalpha decreases response to substance EXP 6480464 Bilirubin results in decreased susceptibility to IL18 protein CTD PMID:18215737 IL18 Human biliverdin multiple interactions EXP 6480464 Biliverdine inhibits the reaction [IL18 protein results in decreased phosphorylation of AKT1 protein] and Biliverdine inhibits the reaction [IL18 protein results in increased expression of PTEN protein] CTD PMID:18215737 IL18 Human biliverdin decreases response to substance EXP 6480464 Biliverdine results in decreased susceptibility to IL18 protein CTD PMID:18215737 IL18 Human bis(2-chloroethyl) sulfide decreases expression ISO Il18 (Mus musculus) 6480464 Mustard Gas results in decreased expression of IL18 mRNA CTD PMID:18955075 IL18 Human bis(2-ethylhexyl) phthalate multiple interactions ISO Il18 (Mus musculus) 6480464 Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL18 protein] CTD PMID:36610486 IL18 Human bis(2-ethylhexyl) phthalate increases expression ISO Il18 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of IL18 protein CTD PMID:36610486 IL18 Human bisphenol A decreases expression ISO Il18 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of IL18 mRNA CTD PMID:12075121 IL18 Human bisphenol A multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [bisphenol A affects the expression of IL18 mRNA] CTD PMID:35439536 IL18 Human bisphenol A decreases methylation EXP 6480464 bisphenol A results in decreased methylation of IL18 gene CTD PMID:31601247 IL18 Human bisphenol A increases expression ISO Il18 (Mus musculus) 6480464 bisphenol A results in increased expression of IL18 mRNA and bisphenol A results in increased expression of IL18 protein CTD PMID:32540565 IL18 Human bisphenol A multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Fluvastatin inhibits the reaction [bisphenol A results in increased expression of IL18 protein] more ... CTD PMID:28285737 and PMID:35465754 IL18 Human bisphenol A increases expression ISO Il18 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of IL18 mRNA and bisphenol A results in increased expression of IL18 protein CTD PMID:28285737 more ... IL18 Human bisphenol A decreases expression ISO Il18 (Mus musculus) 6480464 bisphenol A results in decreased expression of IL18 mRNA CTD PMID:26063408 IL18 Human bisphenol A increases secretion EXP 6480464 bisphenol A results in increased secretion of IL18 protein CTD PMID:25878060 IL18 Human bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of IL18 mRNA CTD PMID:25878060 and PMID:35439536 IL18 Human bisphenol F decreases expression ISO Il18 (Mus musculus) 6480464 bisphenol F results in decreased expression of IL18 mRNA CTD PMID:30951980 IL18 Human boric acid multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [boric acid results in increased abundance of Boron] inhibits the reaction [Acetaminophen results in increased expression of IL18 protein] CTD PMID:35020164 IL18 Human boron atom multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [boric acid results in increased abundance of Boron] inhibits the reaction [Acetaminophen results in increased expression of IL18 protein] CTD PMID:35020164 IL18 Human BQ 123 multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [cyclo(Trp-Asp-Pro-Val-Leu) binds to and results in decreased activity of EDNRA protein] inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 IL18 Human Brevianamide A increases expression ISO Il18 (Mus musculus) 6480464 brevianamide A results in increased expression of IL18 mRNA CTD PMID:19818335 IL18 Human butyric acid increases expression EXP 6480464 Butyric Acid results in increased expression of IL18 mRNA CTD PMID:17928716 IL18 Human cadmium atom increases expression EXP 6480464 Cadmium results in increased expression of IL18 mRNA CTD PMID:33559965 IL18 Human cadmium atom multiple interactions ISO Il18 (Mus musculus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL18 mRNA CTD PMID:33359024 IL18 Human cadmium atom multiple interactions EXP 6480464 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2 more ... CTD PMID:34510229 and PMID:37300869 IL18 Human cadmium atom multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL18 mRNA CTD PMID:34510229 IL18 Human cadmium dichloride increases expression ISO Il18 (Rattus norvegicus) 6480464 Cadmium Chloride results in increased expression of IL18 protein CTD PMID:28759707 IL18 Human cadmium dichloride multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL18 mRNA CTD PMID:34510229 IL18 Human cadmium dichloride multiple interactions EXP 6480464 7-methyl-5-(1-((3-(trifluoromethyl)phenyl)acetyl)-2 more ... CTD PMID:30796460 more ... IL18 Human cadmium dichloride increases secretion EXP 6480464 Cadmium Chloride results in increased secretion of IL18 protein CTD PMID:30796460 IL18 Human cadmium dichloride multiple interactions ISO Il18 (Mus musculus) 6480464 4-phenylbutyric acid inhibits the reaction [Cadmium Chloride results in increased expression of IL18 mRNA] and [Cadmium Chloride results in increased abundance of Cadmium] which results in increased expression of IL18 mRNA CTD PMID:30796460 and PMID:33359024 IL18 Human cadmium dichloride increases expression EXP 6480464 Cadmium Chloride results in increased expression of IL18 mRNA CTD PMID:30796460 IL18 Human cannabidiol multiple interactions EXP 6480464 iodopravadoline inhibits the reaction [Cannabidiol results in decreased expression of IL18 protein] and Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of IL18 protein] CTD PMID:27932991 IL18 Human cannabidiol decreases expression ISO Il18 (Mus musculus) 6480464 Cannabidiol results in decreased expression of IL18 protein CTD PMID:34269108 IL18 Human cannabidiol decreases expression EXP 6480464 Cannabidiol results in decreased expression of IL18 mRNA and Cannabidiol results in decreased expression of IL18 protein CTD PMID:27932991 and PMID:34269108 IL18 Human carbon monoxide decreases response to substance EXP 6480464 Carbon Monoxide results in decreased susceptibility to IL18 protein CTD PMID:18215737 IL18 Human carbon monoxide multiple interactions EXP 6480464 Carbon Monoxide inhibits the reaction [IL18 protein results in decreased phosphorylation of AKT1 protein] and Carbon Monoxide inhibits the reaction [IL18 protein results in increased expression of PTEN protein] CTD PMID:18215737 IL18 Human carbon nanotube decreases expression ISO Il18 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:25620056 IL18 Human carbon nanotube increases secretion ISO Il18 (Mus musculus) 6480464 Nanotubes and Carbon results in increased secretion of IL18 protein CTD PMID:19371758 IL18 Human carbonyl cyanide p-trifluoromethoxyphenylhydrazone decreases expression EXP 6480464 Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone results in decreased expression of IL18 mRNA CTD PMID:16039398 IL18 Human cefaloridine increases expression ISO Il18 (Rattus norvegicus) 6480464 Cephaloridine results in increased expression of IL18 mRNA CTD PMID:18500788 IL18 Human celastrol multiple interactions ISO Il18 (Rattus norvegicus) 6480464 celastrol inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein] more ... CTD PMID:32470352 IL18 Human cerium trichloride increases expression ISO Il18 (Mus musculus) 6480464 cerous chloride results in increased expression of IL18 CTD PMID:23712967 IL18 Human chloroethene decreases expression ISO Il18 (Mus musculus) 6480464 Vinyl Chloride results in decreased expression of IL18 mRNA CTD PMID:34717031 IL18 Human chloropicrin increases expression EXP 6480464 chloropicrin results in increased expression of IL18 mRNA CTD PMID:26352163 IL18 Human chloroquine multiple interactions EXP 6480464 Chloroquine promotes the reaction [[lipopolysaccharide and Escherichia coli O111 B4 co-treated with sodium arsenite] results in increased expression of IL18 protein] CTD PMID:34920032 IL18 Human chlorpyrifos multiple interactions EXP 6480464 NFE2L2 protein inhibits the reaction [Chlorpyrifos results in increased expression of IL18 mRNA] and NFE2L2 protein inhibits the reaction [Chlorpyrifos results in increased expression of IL18 protein] CTD PMID:30835941 IL18 Human chlorpyrifos increases expression EXP 6480464 Chlorpyrifos results in increased expression of IL18 mRNA and Chlorpyrifos results in increased expression of IL18 protein CTD PMID:30835941 IL18 Human choline increases methylation EXP 6480464 Choline results in increased methylation of IL18 gene CTD PMID:30116142 IL18 Human choline multiple interactions ISO Il18 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL18 mRNA more ... CTD PMID:37023836 IL18 Human cimetidine multiple interactions EXP 6480464 CASP1 protein affects the reaction [Cimetidine results in increased expression of IL18 protein] more ... CTD PMID:16723495 IL18 Human cimetidine multiple interactions ISO Il18 (Mus musculus) 6480464 HRH2 protein affects the reaction [Cimetidine results in increased expression of IL18 protein] CTD PMID:16723495 IL18 Human cimetidine increases expression ISO Il18 (Mus musculus) 6480464 Cimetidine results in increased expression of IL18 protein CTD PMID:16723495 IL18 Human cimetidine increases expression EXP 6480464 Cimetidine results in increased expression of IL18 protein CTD PMID:16723495 IL18 Human cinnamyl alcohol increases expression EXP 6480464 cinnamyl alcohol results in increased expression of IL18 protein CTD PMID:23063874 IL18 Human cisplatin decreases expression EXP 6480464 Cisplatin results in decreased expression of IL18 CTD PMID:17021654 IL18 Human cisplatin multiple interactions ISO Il18 (Rattus norvegicus) 6480464 vanillin inhibits the reaction [Cisplatin results in increased expression of IL18 protein] CTD PMID:29216766 IL18 Human cisplatin increases expression ISO Il18 (Rattus norvegicus) 6480464 Cisplatin results in increased expression of IL18 protein CTD PMID:29216766 IL18 Human cisplatin decreases expression ISO Il18 (Rattus norvegicus) 6480464 Cisplatin results in decreased expression of IL18 mRNA CTD PMID:35842499 IL18 Human cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of IL18 mRNA CTD PMID:27594783 IL18 Human cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with Paclitaxel] results in increased expression of IL18 mRNA CTD PMID:20705681 IL18 Human cisplatin increases expression ISO Il18 (Mus musculus) 6480464 Cisplatin results in increased expression of IL18 mRNA and Cisplatin results in increased expression of IL18 protein CTD PMID:21151649 more ... IL18 Human citral increases expression EXP 6480464 citral results in increased expression of IL18 protein CTD PMID:23063874 IL18 Human clenbuterol increases expression ISO Il18 (Mus musculus) 6480464 Clenbuterol results in increased expression of IL18 mRNA and Clenbuterol results in increased expression of IL18 protein CTD PMID:15178407 IL18 Human clofibrate decreases expression ISO Il18 (Mus musculus) 6480464 Clofibrate results in decreased expression of IL18 mRNA CTD PMID:17585979 IL18 Human cobalt atom multiple interactions ISO Il18 (Mus musculus) 6480464 [Cobalt co-treated with Organometallic Compounds] results in increased expression of IL18 mRNA CTD PMID:22147119 IL18 Human cobalt atom multiple interactions EXP 6480464 NLRP3 protein promotes the reaction [Cobalt results in increased secretion of IL18 protein] CTD PMID:32805375 IL18 Human cobalt atom increases secretion EXP 6480464 Cobalt results in increased secretion of IL18 protein CTD PMID:32805375 IL18 Human cobalt atom increases expression ISO Il18 (Mus musculus) 6480464 Cobalt results in increased expression of IL18 mRNA CTD PMID:22147119 IL18 Human cobalt atom multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Nickel co-treated with Cobalt co-treated with Tungsten] results in decreased expression of IL18 mRNA CTD PMID:22198552 IL18 Human cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of IL18 mRNA CTD PMID:19376846 IL18 Human cobalt dichloride decreases expression ISO Il18 (Rattus norvegicus) 6480464 cobaltous chloride results in decreased expression of IL18 mRNA CTD PMID:24386269 IL18 Human copper(II) sulfate increases expression EXP 6480464 Copper Sulfate results in increased expression of IL18 mRNA CTD PMID:19549813 IL18 Human copper(II) sulfate increases secretion ISO Il18 (Mus musculus) 6480464 Copper Sulfate results in increased secretion of IL18 protein CTD PMID:37353053 IL18 Human copper(II) sulfate multiple interactions ISO Il18 (Mus musculus) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in increased secretion of IL18 protein] CTD PMID:37353053 IL18 Human cordycepin multiple interactions ISO Il18 (Mus musculus) 6480464 cordycepin inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA] CTD PMID:28962083 IL18 Human cordycepin multiple interactions EXP 6480464 cordycepin inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA] CTD PMID:28962083 IL18 Human corn oil increases expression ISO Il18 (Mus musculus) 6480464 Corn Oil results in increased expression of IL18 mRNA CTD PMID:33263755 IL18 Human crocidolite asbestos increases secretion EXP 6480464 Asbestos and Crocidolite results in increased secretion of IL18 protein CTD PMID:23937860 and PMID:28056339 IL18 Human crocidolite asbestos multiple interactions EXP 6480464 IL1RN protein inhibits the reaction [Asbestos and Crocidolite results in increased secretion of IL18 protein] CTD PMID:28056339 IL18 Human crocidolite asbestos multiple interactions ISO Il18 (Mus musculus) 6480464 CASP1 protein affects the reaction [Asbestos and Crocidolite results in increased expression of IL18 protein] CTD PMID:28056339 IL18 Human crocidolite asbestos increases expression ISO Il18 (Mus musculus) 6480464 Asbestos and Crocidolite results in increased expression of IL18 protein CTD PMID:28056339 IL18 Human crocidolite asbestos decreases expression EXP 6480464 Asbestos and Crocidolite results in decreased expression of IL18 mRNA CTD PMID:24160326 and PMID:29523930 IL18 Human curcumin multiple interactions EXP 6480464 Curcumin inhibits the reaction [IL18 protein results in increased expression of VEGFA mRNA] more ... CTD PMID:16368150 and PMID:17399992 IL18 Human curcumin multiple interactions ISO Il18 (Mus musculus) 6480464 Curcumin inhibits the reaction [Aflatoxin B1 results in increased expression of IL18 mRNA] and Curcumin inhibits the reaction [Aflatoxin B1 results in increased secretion of IL18 protein] CTD PMID:35063475 IL18 Human curcumin decreases expression ISO Il18 (Mus musculus) 6480464 Curcumin results in decreased expression of IL18 mRNA CTD PMID:16751071 IL18 Human curcumin decreases expression EXP 6480464 Curcumin results in decreased expression of IL18 mRNA and Curcumin results in decreased expression of IL18 protein CTD PMID:17399992 IL18 Human Curcumol decreases expression EXP 6480464 curcumol results in decreased expression of IL18 protein CTD PMID:32344006 IL18 Human cycloheximide multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Cycloheximide inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 IL18 Human cyclophosphamide increases expression ISO Il18 (Rattus norvegicus) 6480464 Cyclophosphamide results in increased expression of IL18 protein CTD PMID:18848347 IL18 Human cyclosporin A increases expression EXP 6480464 Cyclosporine results in increased expression of IL18 mRNA CTD PMID:20106945 IL18 Human cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of IL18 mRNA CTD PMID:27989131 IL18 Human cyclosporin A multiple interactions ISO Il18 (Mus musculus) 6480464 Cyclosporine inhibits the reaction [Picryl Chloride results in increased expression of IL18 protein] CTD PMID:16442096 IL18 Human cypermethrin multiple interactions ISO Il18 (Rattus norvegicus) 6480464 CXCL16 protein promotes the reaction [cypermethrin results in increased expression of IL18 mRNA] CTD PMID:35512476 IL18 Human cypermethrin increases expression ISO Il18 (Rattus norvegicus) 6480464 cypermethrin results in increased expression of IL18 mRNA CTD PMID:35512476 IL18 Human D-glucose increases secretion ISO Il18 (Mus musculus) 6480464 Glucose results in increased secretion of IL18 protein CTD PMID:34212273 IL18 Human D-glucose increases secretion EXP 6480464 Glucose results in increased secretion of IL18 protein CTD PMID:35607288 IL18 Human D-glucose multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL18 protein and diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL18 protein] CTD PMID:35191607 IL18 Human D-glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased secretion of IL18 protein more ... CTD PMID:35607288 more ... IL18 Human D-glucose multiple interactions ISO Il18 (Mus musculus) 6480464 GSDMD protein affects the reaction [Glucose results in increased secretion of IL18 protein] and Hirudins inhibits the reaction [Glucose results in increased secretion of IL18 protein] CTD PMID:34212273 IL18 Human D-glucose increases expression ISO Il18 (Mus musculus) 6480464 Glucose results in increased expression of IL18 mRNA CTD PMID:34212273 IL18 Human D-glucose increases expression EXP 6480464 Glucose results in increased expression of IL18 mRNA and Glucose results in increased expression of IL18 protein CTD PMID:36066211 more ... IL18 Human deoxynivalenol decreases expression ISO Il18 (Mus musculus) 6480464 deoxynivalenol results in decreased expression of IL18 mRNA CTD PMID:22968694 IL18 Human deoxynivalenol increases secretion ISO Il18 (Mus musculus) 6480464 deoxynivalenol results in increased secretion of IL18 protein CTD PMID:35925383 and PMID:36309173 IL18 Human deoxynivalenol multiple interactions ISO Il18 (Mus musculus) 6480464 acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [deoxynivalenol results in increased expression of IL18 mRNA] more ... CTD PMID:35925383 and PMID:36309173 IL18 Human deoxynivalenol increases expression ISO Il18 (Mus musculus) 6480464 deoxynivalenol results in increased expression of IL18 mRNA and deoxynivalenol results in increased expression of IL18 protein CTD PMID:35925383 and PMID:36309173 IL18 Human dexamethasone multiple interactions EXP 6480464 Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein] more ... CTD PMID:18951874 IL18 Human dexamethasone decreases expression ISO Il18 (Mus musculus) 6480464 Dexamethasone results in decreased expression of IL18 mRNA CTD PMID:25900201 IL18 Human dexamethasone multiple interactions ISO Il18 (Mus musculus) 6480464 Amiodarone promotes the reaction [Dexamethasone results in decreased expression of IL18 mRNA] and Dexamethasone inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein] CTD PMID:25448682 and PMID:25900201 IL18 Human dexamethasone increases expression ISO Il18 (Mus musculus) 6480464 Dexamethasone results in increased expression of IL18 mRNA CTD PMID:21041162 IL18 Human dexmedetomidine multiple interactions EXP 6480464 Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of IL18 protein] more ... CTD PMID:36858639 IL18 Human dextran sulfate affects response to substance ISO Il18 (Mus musculus) 6480464 IL18 protein affects the susceptibility to Dextran Sulfate CTD PMID:12940437 IL18 Human dextran sulfate increases secretion ISO Il18 (Mus musculus) 6480464 Dextran Sulfate results in increased secretion of IL18 protein CTD PMID:30270565 and PMID:37001609 IL18 Human dextran sulfate increases expression ISO Il18 (Rattus norvegicus) 6480464 Dextran Sulfate results in increased expression of IL18 protein CTD PMID:32470352 IL18 Human dextran sulfate multiple interactions ISO Il18 (Rattus norvegicus) 6480464 celastrol inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein] more ... CTD PMID:32470352 IL18 Human dextran sulfate multiple interactions ISO Il18 (Mus musculus) 6480464 [Dextran Sulfate co-treated with Zearalenone] results in increased expression of IL18 mRNA more ... CTD PMID:25448682 more ... IL18 Human dextran sulfate increases expression ISO Il18 (Mus musculus) 6480464 Dextran Sulfate results in increased expression of IL18 mRNA and Dextran Sulfate results in increased expression of IL18 protein CTD PMID:25448682 and PMID:30270565 IL18 Human Diallyl sulfide multiple interactions ISO Il18 (Mus musculus) 6480464 allyl sulfide inhibits the reaction [[ethylene dichloride co-treated with Ethanol] results in increased expression of IL18 protein] CTD PMID:37150348 IL18 Human diarsenic trioxide increases expression EXP 6480464 Arsenic Trioxide results in increased expression of IL18 mRNA CTD PMID:36801614 IL18 Human diarsenic trioxide increases secretion EXP 6480464 Arsenic Trioxide results in increased secretion of IL18 protein CTD PMID:35226250 IL18 Human diarsenic trioxide multiple interactions EXP 6480464 IGF2BP2 protein promotes the reaction [Arsenic Trioxide results in increased secretion of IL18 protein] and METTL14 protein promotes the reaction [Arsenic Trioxide results in increased secretion of IL18 protein] CTD PMID:35226250 IL18 Human diarsenic trioxide increases secretion ISO Il18 (Mus musculus) 6480464 Arsenic Trioxide results in increased secretion of IL18 protein CTD PMID:35226250 IL18 Human diarsenic trioxide decreases expression ISO Il18 (Mus musculus) 6480464 Arsenic Trioxide results in decreased expression of IL18 CTD PMID:20693187 IL18 Human dibenziodolium multiple interactions EXP 6480464 diphenyleneiodonium inhibits the reaction [IL18 protein results in increased abundance of Reactive Oxygen Species] and diphenyleneiodonium inhibits the reaction [IL18 protein results in increased expression of BSG mRNA] CTD PMID:19561311 IL18 Human dibenziodolium multiple interactions ISO Il18 (Mus musculus) 6480464 diphenyleneiodonium inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL18 protein] and diphenyleneiodonium inhibits the reaction [Silicon Dioxide analog results in increased secretion of IL18 protein] CTD PMID:27311643 IL18 Human dibutyl phthalate multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Benzo(a)pyrene co-treated with Dibutyl Phthalate] results in increased expression of IL18 mRNA and [Benzo(a)pyrene co-treated with Dibutyl Phthalate] results in increased expression of IL18 protein CTD PMID:36592837 IL18 Human dichlorine multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Ozone co-treated with Chlorine] results in decreased expression of IL18 mRNA CTD PMID:18636392 IL18 Human diclofenac multiple interactions ISO Il18 (Rattus norvegicus) 6480464 diacerein inhibits the reaction [Diclofenac results in increased expression of IL18 protein] CTD PMID:38582345 IL18 Human diclofenac increases expression ISO Il18 (Rattus norvegicus) 6480464 Diclofenac results in increased expression of IL18 protein CTD PMID:38582345 IL18 Human dicrotophos decreases expression EXP 6480464 dicrotophos results in decreased expression of IL18 mRNA CTD PMID:28302478 IL18 Human dieckol multiple interactions ISO Il18 (Mus musculus) 6480464 dieckol inhibits the reaction [9 more ... CTD PMID:33347706 IL18 Human dieldrin affects expression ISO Il18 (Rattus norvegicus) 6480464 Dieldrin affects the expression of IL18 mRNA CTD PMID:22546817 IL18 Human diethyl malate affects expression ISO Il18 (Mus musculus) 6480464 diethyl malate affects the expression of IL18 mRNA CTD PMID:24814887 IL18 Human diethyl maleate increases expression EXP 6480464 diethyl maleate results in increased expression of IL18 protein CTD PMID:23063874 IL18 Human diethyl phthalate increases expression ISO Il18 (Mus musculus) 6480464 diethyl phthalate results in increased expression of IL18 protein CTD PMID:37942807 IL18 Human diethylamine increases activity ISO Il18 (Mus musculus) 6480464 diethylamine results in increased activity of IL18 protein CTD PMID:15840424 IL18 Human diethylstilbestrol increases expression ISO Il18 (Rattus norvegicus) 6480464 Diethylstilbestrol results in increased expression of IL18 mRNA CTD PMID:36653537 IL18 Human dihydroartemisinin increases secretion EXP 6480464 artenimol results in increased secretion of IL18 protein CTD PMID:33689708 and PMID:34655567 IL18 Human dihydroartemisinin increases expression EXP 6480464 artenimol results in increased expression of IL18 mRNA and artenimol results in increased expression of IL18 protein CTD PMID:33689708 IL18 Human dihydroartemisinin multiple interactions EXP 6480464 acetyl-aspartyl-glutamyl-valyl-aspartal inhibits the reaction [artenimol results in increased secretion of IL18 protein] more ... CTD PMID:33689708 and PMID:34655567 IL18 Human Dimaprit multiple interactions EXP 6480464 Dimaprit inhibits the reaction [IL18 protein results in decreased expression of IL10 protein] more ... CTD PMID:11752121 and PMID:12364868 IL18 Human diosmetin multiple interactions ISO Il18 (Rattus norvegicus) 6480464 diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL18 protein] and diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL18 protein] CTD PMID:35191607 IL18 Human dioxygen multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [dan-shen root extract co-treated with Andrographis paniculata extract] inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in increased expression of and results in increased secretion of IL18 protein] more ... CTD PMID:26464617 more ... IL18 Human dioxygen multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased secretion of IL18 protein and bellidifolin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased secretion of IL18 protein] CTD PMID:37127800 IL18 Human disodium selenite multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Sodium Selenite inhibits the reaction [bisphenol A results in increased expression of IL18 mRNA] CTD PMID:28285737 IL18 Human disulfiram multiple interactions EXP 6480464 [Disulfiram co-treated with Adenosine Triphosphate] inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein] and Disulfiram inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased secretion of IL18 protein] CTD PMID:33579316 and PMID:33851234 IL18 Human doxorubicin multiple interactions ISO Il18 (Rattus norvegicus) 6480464 geraniol inhibits the reaction [Doxorubicin results in increased expression of IL18 protein] more ... CTD PMID:34343525 and PMID:35764897 IL18 Human doxorubicin increases expression ISO Il18 (Rattus norvegicus) 6480464 Doxorubicin results in increased expression of IL18 mRNA and Doxorubicin results in increased expression of IL18 protein CTD PMID:34343525 and PMID:35764897 IL18 Human elemental boron multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [boric acid results in increased abundance of Boron] inhibits the reaction [Acetaminophen results in increased expression of IL18 protein] CTD PMID:35020164 IL18 Human emodin multiple interactions ISO Il18 (Mus musculus) 6480464 Emodin inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL18 protein] CTD PMID:37023836 IL18 Human eplerenone multiple interactions ISO Il18 (Rattus norvegicus) 6480464 eplerenone inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 IL18 Human epoxiconazole increases expression ISO Il18 (Mus musculus) 6480464 epoxiconazole results in increased expression of IL18 mRNA CTD PMID:35436446 IL18 Human ethanol affects response to substance EXP 6480464 IL18 gene SNP affects the susceptibility to Ethanol CTD PMID:24349532 IL18 Human ethanol increases expression ISO Il18 (Rattus norvegicus) 6480464 Ethanol results in increased expression of IL18 mRNA CTD PMID:34547370 IL18 Human ethanol affects expression ISO Il18 (Mus musculus) 6480464 Ethanol affects the expression of IL18 mRNA CTD PMID:30319688 IL18 Human ethanol multiple interactions EXP 6480464 [Ethanol co-treated with Folic Acid] results in increased expression of IL18 mRNA more ... CTD PMID:23378141 more ... IL18 Human ethanol increases expression ISO Il18 (Mus musculus) 6480464 Ethanol results in increased expression of IL18 mRNA CTD PMID:28964808 IL18 Human ethanol multiple interactions ISO Il18 (Mus musculus) 6480464 [ethylene dichloride co-treated with Ethanol] results in increased expression of IL18 protein more ... CTD PMID:28964808 and PMID:37150348 IL18 Human ethanol increases expression EXP 6480464 Ethanol results in increased expression of IL18 mRNA and Ethanol results in increased expression of IL18 protein CTD PMID:28964808 and PMID:34474091 IL18 Human eugenol increases expression EXP 6480464 Eugenol results in increased expression of IL18 protein CTD PMID:23063874 IL18 Human famotidine multiple interactions EXP 6480464 Famotidine inhibits the reaction [Cimetidine results in increased expression of IL18 protein] more ... CTD PMID:11752121 more ... IL18 Human fasudil multiple interactions ISO Il18 (Rattus norvegicus) 6480464 fasudil inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 IL18 Human felodipine multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Felodipine inhibits the reaction [Fructose results in increased expression of IL18 mRNA] and Felodipine inhibits the reaction [Fructose results in increased expression of IL18 protein] CTD PMID:18504504 IL18 Human ferulic acid multiple interactions ISO Il18 (Mus musculus) 6480464 ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL18 mRNA] CTD PMID:31054998 IL18 Human fluvastatin multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Fluvastatin inhibits the reaction [bisphenol A results in increased expression of IL18 protein] more ... CTD PMID:35465754 IL18 Human folic acid multiple interactions EXP 6480464 [Ethanol co-treated with Folic Acid] results in increased expression of IL18 mRNA CTD PMID:23378141 IL18 Human folic acid increases methylation EXP 6480464 Folic Acid results in increased methylation of IL18 gene CTD PMID:30116142 IL18 Human folic acid increases expression EXP 6480464 Folic Acid results in increased expression of IL18 mRNA CTD PMID:28752528 IL18 Human folic acid increases expression ISO Il18 (Mus musculus) 6480464 Folic Acid results in increased expression of IL18 protein CTD PMID:31593741 and PMID:35191561 IL18 Human folic acid multiple interactions ISO Il18 (Mus musculus) 6480464 [1 more ... CTD PMID:22206623 more ... IL18 Human folpet decreases expression ISO Il18 (Mus musculus) 6480464 folpet results in decreased expression of IL18 mRNA CTD PMID:31558096 IL18 Human formaldehyde increases expression ISO Il18 (Mus musculus) 6480464 Formaldehyde results in increased expression of IL18 mRNA CTD PMID:12161283 IL18 Human Fraxinellone multiple interactions ISO Il18 (Mus musculus) 6480464 fraxinellone inhibits the reaction [Dextran Sulfate results in increased expression of IL18 protein] and fraxinellone inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 protein] CTD PMID:25448682 IL18 Human Fraxinellone multiple interactions EXP 6480464 fraxinellone inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 protein] CTD PMID:25448682 IL18 Human fructose multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Allopurinol inhibits the reaction [Fructose results in increased expression of IL18 protein] more ... CTD PMID:18504504 and PMID:22426011 IL18 Human fructose increases expression ISO Il18 (Rattus norvegicus) 6480464 Fructose results in increased expression of IL18 mRNA and Fructose results in increased expression of IL18 protein CTD PMID:18504504 and PMID:22426011 IL18 Human fulvestrant multiple interactions ISO Il18 (Mus musculus) 6480464 [fulvestrant co-treated with Mifepristone] inhibits the reaction [[Progesterone co-treated with Estrogens] inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA]] CTD PMID:17850464 IL18 Human fulvestrant multiple interactions EXP 6480464 Fulvestrant inhibits the reaction [bisphenol A affects the expression of IL18 mRNA] CTD PMID:35439536 IL18 Human fumonisin B1 multiple interactions ISO Il18 (Mus musculus) 6480464 deoxynivalenol promotes the reaction [fumonisin B1 results in increased expression of IL18 mRNA] more ... CTD PMID:36309173 IL18 Human fumonisin B1 increases secretion ISO Il18 (Mus musculus) 6480464 fumonisin B1 results in increased secretion of IL18 protein CTD PMID:36309173 IL18 Human fumonisin B1 increases expression ISO Il18 (Mus musculus) 6480464 fumonisin B1 results in increased expression of IL18 mRNA and fumonisin B1 results in increased expression of IL18 protein CTD PMID:36309173 IL18 Human furan decreases expression ISO Il18 (Mus musculus) 6480464 furan results in decreased expression of IL18 mRNA CTD PMID:20194422 IL18 Human furan multiple interactions ISO Il18 (Mus musculus) 6480464 rhodioloside inhibits the reaction [furan results in increased expression of IL18 mRNA] and rhodioloside inhibits the reaction [furan results in increased expression of IL18 protein] CTD PMID:34450210 IL18 Human furan increases expression ISO Il18 (Mus musculus) 6480464 furan results in increased expression of IL18 mRNA and furan results in increased expression of IL18 protein CTD PMID:34450210 IL18 Human genistein decreases expression ISO Il18 (Rattus norvegicus) 6480464 Genistein results in decreased expression of IL18 mRNA CTD PMID:12075121 IL18 Human gentamycin decreases expression EXP 6480464 Gentamicins results in decreased expression of IL18 mRNA CTD PMID:29992668 IL18 Human gentamycin decreases expression ISO Il18 (Rattus norvegicus) 6480464 Gentamicins results in decreased expression of IL18 mRNA CTD PMID:33387578 IL18 Human geranial increases expression EXP 6480464 citral results in increased expression of IL18 protein CTD PMID:23063874 IL18 Human geraniol multiple interactions ISO Il18 (Mus musculus) 6480464 geraniol inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide more ... CTD PMID:21430599 IL18 Human geraniol multiple interactions ISO Il18 (Rattus norvegicus) 6480464 geraniol inhibits the reaction [Doxorubicin results in increased expression of IL18 protein] CTD PMID:34343525 IL18 Human ginsenoside Rb1 multiple interactions ISO Il18 (Mus musculus) 6480464 ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in increased expression of and results in increased secretion of IL18 protein] CTD PMID:38373586 IL18 Human ginsenoside Rb1 multiple interactions ISO Il18 (Rattus norvegicus) 6480464 ginsenoside Rb1 inhibits the reaction [alpha-Chlorohydrin results in increased secretion of IL18 protein] CTD PMID:38373586 IL18 Human glucose increases expression EXP 6480464 Glucose results in increased expression of IL18 mRNA and Glucose results in increased expression of IL18 protein CTD PMID:36066211 more ... IL18 Human glucose multiple interactions EXP 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased secretion of IL18 protein more ... CTD PMID:35607288 more ... IL18 Human glucose multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL18 protein and diosmetin inhibits the reaction [[Oxygen deficiency co-treated with Glucose deficiency] results in increased expression of IL18 protein] CTD PMID:35191607 IL18 Human glucose increases secretion EXP 6480464 Glucose results in increased secretion of IL18 protein CTD PMID:35607288 IL18 Human glucose increases expression ISO Il18 (Mus musculus) 6480464 Glucose results in increased expression of IL18 mRNA CTD PMID:34212273 IL18 Human glucose multiple interactions ISO Il18 (Mus musculus) 6480464 GSDMD protein affects the reaction [Glucose results in increased secretion of IL18 protein] and Hirudins inhibits the reaction [Glucose results in increased secretion of IL18 protein] CTD PMID:34212273 IL18 Human glucose increases secretion ISO Il18 (Mus musculus) 6480464 Glucose results in increased secretion of IL18 protein CTD PMID:34212273 IL18 Human glyburide multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Glyburide inhibits the reaction [Paraquat results in increased expression of IL18 protein] CTD PMID:25338942 IL18 Human glyburide multiple interactions ISO Il18 (Mus musculus) 6480464 Glyburide inhibits the reaction [Ozone results in increased expression of IL18 protein] and Glyburide inhibits the reaction [Paraquat results in increased secretion of IL18 protein] CTD PMID:25338942 and PMID:32167222 IL18 Human glyoxal increases expression EXP 6480464 Glyoxal results in increased expression of IL18 protein CTD PMID:23063874 IL18 Human gossypin multiple interactions ISO Il18 (Rattus norvegicus) 6480464 gossypin inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 protein] CTD PMID:37148149 IL18 Human graphene oxide increases expression ISO Il18 (Mus musculus) 6480464 graphene oxide analog results in increased expression of IL18 mRNA and graphene oxide results in increased expression of IL18 mRNA CTD PMID:33227293 IL18 Human graphite increases expression ISO Il18 (Rattus norvegicus) 6480464 Graphite results in increased expression of IL18 protein CTD PMID:29933104 IL18 Human hemin multiple interactions EXP 6480464 Hemin inhibits the reaction [IL18 protein results in decreased expression of MAPK11 protein] more ... CTD PMID:18215737 IL18 Human hemin decreases response to substance EXP 6480464 Hemin results in decreased susceptibility to IL18 protein CTD PMID:18215737 IL18 Human hexachlorobenzene increases expression ISO Il18 (Rattus norvegicus) 6480464 Hexachlorobenzene results in increased expression of IL18 mRNA CTD PMID:15159207 IL18 Human hexadecanoic acid increases expression ISO Il18 (Rattus norvegicus) 6480464 Palmitic Acid results in increased expression of IL18 mRNA and Palmitic Acid results in increased expression of IL18 protein CTD PMID:35235096 and PMID:37244597 IL18 Human hexadecanoic acid increases cleavage ISO Il18 (Rattus norvegicus) 6480464 Palmitic Acid results in increased cleavage of IL18 protein CTD PMID:37244597 IL18 Human hexadecanoic acid multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Lead promotes the reaction [Palmitic Acid results in increased cleavage of IL18 protein] more ... CTD PMID:35235096 and PMID:37244597 IL18 Human histamine multiple interactions EXP 6480464 [IL12A protein binds to IL12B protein] inhibits the reaction [Histamine inhibits the reaction [IL18 protein results in decreased expression of IL10 protein]] more ... CTD PMID:11752121 more ... IL18 Human histamine increases expression ISO Il18 (Mus musculus) 6480464 Histamine results in increased expression of IL18 protein CTD PMID:16723495 IL18 Human histamine multiple interactions ISO Il18 (Mus musculus) 6480464 HRH2 protein affects the reaction [Histamine results in increased expression of IL18 protein] CTD PMID:16723495 IL18 Human histamine increases expression EXP 6480464 Histamine results in increased expression of IL18 protein CTD PMID:16723495 IL18 Human Honokiol multiple interactions EXP 6480464 honokiol inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 protein] CTD PMID:21147091 IL18 Human hydrocortisone succinate decreases secretion EXP 6480464 hydrocortisone hemisuccinate results in decreased secretion of IL18 protein CTD PMID:20421217 IL18 Human hydrogen peroxide multiple interactions EXP 6480464 Hydrogen Peroxide inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein]] and Theophylline inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein]]] CTD PMID:18951874 IL18 Human hydrogen peroxide decreases expression EXP 6480464 Hydrogen Peroxide results in decreased expression of IL18 mRNA CTD PMID:12419474 and PMID:26339600 IL18 Human hydrogen peroxide affects expression EXP 6480464 Hydrogen Peroxide affects the expression of IL18 mRNA CTD PMID:21179406 IL18 Human hydroquinone multiple interactions EXP 6480464 2-methyl-2H-pyrazole-3-carboxylic acid (2-methyl-4-o-tolylazophenyl)amide inhibits the reaction [hydroquinone results in increased secretion of IL18 protein] more ... CTD PMID:36646296 IL18 Human hydroquinone increases secretion EXP 6480464 hydroquinone results in increased secretion of IL18 protein CTD PMID:36646296 IL18 Human hydroxysafflor yellow A multiple interactions ISO Il18 (Mus musculus) 6480464 hydroxysafflor yellow A inhibits the reaction [Dextran Sulfate results in increased secretion of IL18 protein] CTD PMID:37001609 IL18 Human ibuprofen multiple interactions ISO Il18 (Mus musculus) 6480464 Ibuprofen inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL18 protein] and Ibuprofen results in decreased expression of and results in decreased secretion of IL18 protein CTD PMID:36088791 IL18 Human IC-87114 multiple interactions ISO Il18 (Mus musculus) 6480464 IC 87114 inhibits the reaction [Toluene 2 and 4-Diisocyanate results in increased secretion of IL18 protein] CTD PMID:33711354 IL18 Human ICI 118551 multiple interactions ISO Il18 (Mus musculus) 6480464 ICI 118551 inhibits the reaction [Isoproterenol results in increased expression of IL18 mRNA] and ICI 118551 inhibits the reaction [Isoproterenol results in increased expression of IL18 protein] CTD PMID:15178407 IL18 Human imiquimod increases expression ISO Il18 (Mus musculus) 6480464 Imiquimod results in increased expression of IL18 mRNA CTD PMID:31054998 IL18 Human imiquimod multiple interactions ISO Il18 (Mus musculus) 6480464 ferulic acid inhibits the reaction [Imiquimod results in increased expression of IL18 mRNA] CTD PMID:31054998 IL18 Human immunological adjuvant multiple interactions EXP 6480464 [Adjuvants more ... CTD PMID:17404311 IL18 Human indometacin increases expression ISO Il18 (Rattus norvegicus) 6480464 Indomethacin results in increased expression of IL18 mRNA and Indomethacin results in increased expression of IL18 protein CTD PMID:18996434 IL18 Human irinotecan multiple interactions EXP 6480464 [Fluorouracil co-treated with Irinotecan] results in decreased expression of IL18 mRNA more ... CTD PMID:16391804 and PMID:26431797 IL18 Human irinotecan multiple interactions ISO Il18 (Mus musculus) 6480464 [Irinotecan co-treated with Lipopolysaccharides] results in increased expression of and results in increased secretion of IL18 protein more ... CTD PMID:26431797 IL18 Human irinotecan increases expression ISO Il18 (Mus musculus) 6480464 Irinotecan results in increased expression of IL18 mRNA and Irinotecan results in increased expression of IL18 protein CTD PMID:26431797 IL18 Human iron atom multiple interactions EXP 6480464 Iron affects the reaction [IL18 protein results in increased secretion of IFNG protein] CTD PMID:15799959 IL18 Human iron(0) multiple interactions EXP 6480464 Iron affects the reaction [IL18 protein results in increased secretion of IFNG protein] CTD PMID:15799959 IL18 Human isoeugenol increases expression EXP 6480464 isoeugenol results in increased expression of IL18 protein CTD PMID:23063874 IL18 Human isoflurane multiple interactions ISO Il18 (Mus musculus) 6480464 N-(1 more ... CTD PMID:35187972 IL18 Human isoflurane increases expression ISO Il18 (Mus musculus) 6480464 Isoflurane results in increased expression of IL18 protein CTD PMID:35187972 IL18 Human isoprenaline multiple interactions ISO Il18 (Mus musculus) 6480464 ADRB2 protein affects the reaction [Isoproterenol results in increased expression of IL18 mRNA] more ... CTD PMID:15178407 IL18 Human isoprenaline increases expression ISO Il18 (Rattus norvegicus) 6480464 Isoproterenol results in increased expression of IL18 protein CTD PMID:24286936 IL18 Human isoprenaline decreases expression ISO Il18 (Mus musculus) 6480464 Isoproterenol results in decreased expression of IL18 mRNA CTD PMID:21335049 IL18 Human ivermectin decreases expression EXP 6480464 Ivermectin results in decreased expression of IL18 protein CTD PMID:32959892 IL18 Human JTE-013 multiple interactions ISO Il18 (Rattus norvegicus) 6480464 JTE 013 inhibits the reaction [sphingosine 1-phosphate results in increased expression of IL18 protein] CTD PMID:37169277 IL18 Human L-methionine multiple interactions ISO Il18 (Mus musculus) 6480464 [Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL18 mRNA more ... CTD PMID:37023836 IL18 Human lead diacetate affects expression ISO Il18 (Mus musculus) 6480464 lead acetate affects the expression of IL18 protein CTD PMID:21322097 IL18 Human lead diacetate increases expression ISO Il18 (Rattus norvegicus) 6480464 lead acetate results in increased expression of IL18 mRNA CTD PMID:33862172 IL18 Human lead(0) multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Lead co-treated with Dietary Fats] results in increased cleavage of IL18 protein more ... CTD PMID:37244597 IL18 Human lead(0) increases expression ISO Il18 (Rattus norvegicus) 6480464 Lead results in increased expression of IL18 protein CTD PMID:37244597 IL18 Human lead(0) increases cleavage ISO Il18 (Rattus norvegicus) 6480464 Lead results in increased cleavage of IL18 protein CTD PMID:37244597 IL18 Human lipid As increases expression EXP 6480464 Lipid A results in increased expression of IL18 mRNA CTD PMID:16299289 IL18 Human lipopolysaccharide multiple interactions EXP 6480464 3-methyladenine promotes the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein] more ... CTD PMID:17399992 more ... IL18 Human lipopolysaccharide multiple interactions ISO Il18 (Rattus norvegicus) 6480464 4-phenylbutyric acid inhibits the reaction [Lipopolysaccharides results in increased secretion of IL18 protein] more ... CTD PMID:35285579 more ... IL18 Human lipopolysaccharide increases secretion ISO Il18 (Rattus norvegicus) 6480464 Lipopolysaccharides results in increased secretion of IL18 protein CTD PMID:37654027 IL18 Human lipopolysaccharide increases secretion EXP 6480464 Lipopolysaccharides results in increased secretion of IL18 protein CTD PMID:15289356 more ... IL18 Human lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of IL18 mRNA and Lipopolysaccharides results in increased expression of IL18 protein CTD PMID:16100009 more ... IL18 Human lipopolysaccharide increases expression ISO Il18 (Rattus norvegicus) 6480464 Lipopolysaccharides results in increased expression of IL18 mRNA and Lipopolysaccharides results in increased expression of IL18 protein CTD PMID:21882482 more ... IL18 Human lipopolysaccharide increases expression ISO Il18 (Mus musculus) 6480464 Lipopolysaccharides results in increased expression of IL18 mRNA and Lipopolysaccharides results in increased expression of IL18 protein CTD PMID:17321000 more ... IL18 Human lipopolysaccharide affects expression ISO Il18 (Mus musculus) 6480464 Lipopolysaccharides affects the expression of IL18 protein CTD PMID:21055422 IL18 Human lipopolysaccharide multiple interactions ISO Il18 (Mus musculus) 6480464 (+)-JQ1 compound inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA] more ... CTD PMID:15933225 more ... IL18 Human lixisenatide multiple interactions EXP 6480464 lixisenatide inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA] and lixisenatide inhibits the reaction [Lipopolysaccharides results in increased secretion of IL18 protein] CTD PMID:38229325 IL18 Human loganin multiple interactions ISO Il18 (Mus musculus) 6480464 loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL18 protein] and loganin inhibits the reaction [[Dietary Fats co-treated with Streptozocin] results in increased expression of IL18 mRNA] CTD PMID:37473909 IL18 Human loganin multiple interactions EXP 6480464 loganin inhibits the reaction [Glucose results in increased expression of IL18 mRNA] and loganin inhibits the reaction [Glucose results in increased expression of IL18 protein] CTD PMID:37473909 IL18 Human lonafarnib multiple interactions ISO Il18 (Mus musculus) 6480464 geraniol promotes the reaction [lonafarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide more ... CTD PMID:21430599 IL18 Human lonidamine multiple interactions ISO Il18 (Mus musculus) 6480464 lonidamine inhibits the reaction [[lipopolysaccharide more ... CTD PMID:36577999 IL18 Human lovastatin multiple interactions ISO Il18 (Mus musculus) 6480464 [Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide more ... CTD PMID:21430599 IL18 Human lucanthone decreases expression EXP 6480464 Lucanthone results in decreased expression of IL18 mRNA CTD PMID:21148553 IL18 Human LY294002 multiple interactions EXP 6480464 [2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one co-treated with Benzo(a)pyrene] results in increased expression of IL18 protein CTD PMID:30726812 IL18 Human LY294002 multiple interactions ISO Il18 (Rattus norvegicus) 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one inhibits the reaction [sodium bisulfide inhibits the reaction [uranyl acetate results in increased secretion of IL18 protein]] CTD PMID:36094782 IL18 Human LY294002 increases expression EXP 6480464 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one results in increased expression of IL18 protein CTD PMID:30726812 IL18 Human lycopene multiple interactions ISO Il18 (Mus musculus) 6480464 Lycopene inhibits the reaction [Diethylhexyl Phthalate results in increased expression of IL18 protein] CTD PMID:36610486 IL18 Human lysophosphatidylcholine multiple interactions EXP 6480464 GPR4 protein promotes the reaction [Lysophosphatidylcholines results in increased expression of IL18 protein] CTD PMID:34293432 IL18 Human lysophosphatidylcholine increases expression EXP 6480464 Lysophosphatidylcholines results in increased expression of IL18 protein CTD PMID:34293432 IL18 Human m-xylene decreases expression ISO Il18 (Rattus norvegicus) 6480464 3-xylene results in decreased expression of IL18 mRNA CTD PMID:12815608 IL18 Human manganese(II) chloride multiple interactions ISO Il18 (Mus musculus) 6480464 acetovanillone analog inhibits the reaction [manganese chloride results in increased expression of IL18 mRNA] CTD PMID:28539244 IL18 Human manganese(II) chloride increases expression ISO Il18 (Mus musculus) 6480464 manganese chloride results in increased expression of IL18 mRNA CTD PMID:28539244 IL18 Human mangiferin multiple interactions ISO Il18 (Rattus norvegicus) 6480464 mangiferin inhibits the reaction [Galactosamine results in increased expression of IL18 mRNA] CTD PMID:22310181 IL18 Human manumycin A multiple interactions ISO Il18 (Mus musculus) 6480464 geraniol promotes the reaction [manumycin inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide more ... CTD PMID:21430599 IL18 Human melatonin multiple interactions EXP 6480464 Melatonin inhibits the reaction [arsenite results in increased expression of and results in increased secretion of IL18 protein] CTD PMID:36343453 IL18 Human melatonin multiple interactions ISO Il18 (Mus musculus) 6480464 Melatonin affects the reaction [[SELENOM protein affects the susceptibility to Nickel] which affects the expression of IL18 mRNA] and Melatonin inhibits the reaction [Nickel results in increased expression of IL18 mRNA] CTD PMID:36504304 IL18 Human melittin increases expression EXP 6480464 Melitten results in increased expression of IL18 protein CTD PMID:22973906 IL18 Human melittin multiple interactions EXP 6480464 AIM2 protein promotes the reaction [Melitten results in increased expression of IL18 protein] CTD PMID:22973906 IL18 Human mesalamine multiple interactions ISO Il18 (Mus musculus) 6480464 Mesalamine inhibits the reaction [Dextran Sulfate results in increased secretion of IL18 protein] CTD PMID:37001609 IL18 Human metam multiple interactions ISO Il18 (Mus musculus) 6480464 methyldithiocarbamate inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA] CTD PMID:15933225 IL18 Human methamphetamine increases expression ISO Il18 (Mus musculus) 6480464 Methamphetamine results in increased expression of IL18 mRNA and Methamphetamine results in increased expression of IL18 protein CTD PMID:33359793 and PMID:35688268 IL18 Human methamphetamine increases secretion ISO Il18 (Mus musculus) 6480464 Methamphetamine results in increased secretion of IL18 protein CTD PMID:35390362 IL18 Human methamphetamine multiple interactions ISO Il18 (Mus musculus) 6480464 [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased secretion of IL18 protein] and obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of IL18 mRNA] CTD PMID:35390362 and PMID:35688268 IL18 Human methotrexate increases expression EXP 6480464 Methotrexate results in increased expression of IL18 mRNA CTD PMID:17400583 IL18 Human methotrexate multiple interactions ISO Il18 (Rattus norvegicus) 6480464 vanillin inhibits the reaction [Methotrexate results in increased expression of IL18 protein] CTD PMID:29216766 IL18 Human methotrexate multiple interactions EXP 6480464 [Methotrexate co-treated with Glucocorticoids] results in decreased expression of IL18 mRNA CTD PMID:22133036 IL18 Human methoxyacetic acid affects expression ISO Il18 (Mus musculus) 6480464 methoxyacetic acid affects the expression of IL18 mRNA CTD PMID:20421339 IL18 Human metronidazole multiple interactions ISO Il18 (Mus musculus) 6480464 [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased secretion of IL18 protein] CTD PMID:35390362 IL18 Human mevalonic acid multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA]] CTD PMID:18660453 IL18 Human microcystin-LR increases expression ISO Il18 (Rattus norvegicus) 6480464 cyanoginosin LR results in increased expression of IL18 protein CTD PMID:34740672 IL18 Human microcystin-LR multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Dietary Fats co-treated with Cholesterol and Dietary co-treated with cyanoginosin LR] results in increased expression of IL18 protein CTD PMID:34740672 IL18 Human mifepristone multiple interactions ISO Il18 (Mus musculus) 6480464 [fulvestrant co-treated with Mifepristone] inhibits the reaction [[Progesterone co-treated with Estrogens] inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA]] CTD PMID:17850464 IL18 Human mitomycin C decreases expression EXP 6480464 Mitomycin results in decreased expression of IL18 and Mitomycin results in decreased expression of IL18 protein CTD PMID:16019139 and PMID:17021654 IL18 Human Monobutylphthalate affects expression ISO Il18 (Mus musculus) 6480464 monobutyl phthalate affects the expression of IL18 mRNA CTD PMID:20421339 IL18 Human monocrotaline multiple interactions ISO Il18 (Mus musculus) 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL18 mRNA CTD PMID:21224054 IL18 Human muramyl dipeptide multiple interactions ISO Il18 (Mus musculus) 6480464 [Pamidronate results in increased susceptibility to Acetylmuramyl-Alanyl-Isoglutamine] which results in increased secretion of IL18 protein CTD PMID:21282739 IL18 Human mycophenolic acid decreases expression ISO Il18 (Mus musculus) 6480464 Mycophenolic Acid results in decreased expression of IL18 mRNA CTD PMID:19818335 IL18 Human mycotoxin increases expression ISO Il18 (Mus musculus) 6480464 Mycotoxins results in increased expression of IL18 mRNA CTD PMID:19818335 IL18 Human N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions EXP 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Cimetidine results in increased expression of IL18 protein] and N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide inhibits the reaction [Histamine results in increased expression of IL18 protein] CTD PMID:16723495 IL18 Human N-[2-(4-bromocinnamylamino)ethyl]isoquinoline-5-sulfonamide multiple interactions ISO Il18 (Mus musculus) 6480464 N-(2-(4-bromocinnamylamino)ethyl)-5-isoquinolinesulfonamide promotes the reaction [Copper Sulfate results in increased secretion of IL18 protein] CTD PMID:37353053 IL18 Human N-acetyl-L-cysteine multiple interactions ISO Il18 (Mus musculus) 6480464 Acetylcysteine inhibits the reaction [Adenosine Triphosphate results in increased secretion of IL18 protein] more ... CTD PMID:27311643 and PMID:35777681 IL18 Human N-acetyl-L-cysteine multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of IL18 protein] and Acetylcysteine inhibits the reaction [Particulate Matter results in increased expression of IL18 protein] CTD PMID:35020164 and PMID:35285579 IL18 Human N-acetyl-L-cysteine multiple interactions EXP 6480464 Acetylcysteine inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein] more ... CTD PMID:30205151 more ... IL18 Human N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions ISO Il18 (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein] CTD PMID:15178407 IL18 Human N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal multiple interactions EXP 6480464 [lipopolysaccharide more ... CTD PMID:34920032 IL18 Human N-nitrosodimethylamine multiple interactions ISO Il18 (Mus musculus) 6480464 CSF3 protein affects the reaction [Dimethylnitrosamine affects the expression of IL18 mRNA] CTD PMID:17869372 IL18 Human N-nitrosodimethylamine multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Dietary Fats co-treated with Dimethylnitrosamine] results in increased expression of IL18 mRNA CTD PMID:32833043 IL18 Human N-nitrosodimethylamine affects expression ISO Il18 (Mus musculus) 6480464 Dimethylnitrosamine affects the expression of IL18 mRNA CTD PMID:17869372 IL18 Human N1'-[2-[[5-[(dimethylamino)methyl]-2-furanyl]methylthio]ethyl]-N1-methyl-2-nitroethene-1,1-diamine multiple interactions EXP 6480464 Ranitidine inhibits the reaction [Cimetidine results in increased expression of IL18 protein] more ... CTD PMID:11752121 and PMID:16723495 IL18 Human neomycin multiple interactions ISO Il18 (Mus musculus) 6480464 [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased secretion of IL18 protein] CTD PMID:35390362 IL18 Human nickel atom multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Nickel co-treated with Cobalt co-treated with Tungsten] results in decreased expression of IL18 mRNA CTD PMID:22198552 IL18 Human nickel atom increases expression ISO Il18 (Mus musculus) 6480464 Nickel results in increased expression of IL18 mRNA CTD PMID:36504304 IL18 Human nickel atom multiple interactions ISO Il18 (Mus musculus) 6480464 [SELENOM protein affects the susceptibility to Nickel] which affects the expression of IL18 mRNA more ... CTD PMID:36504304 IL18 Human nickel atom decreases expression EXP 6480464 Nickel results in decreased expression of IL18 mRNA CTD PMID:24768652 IL18 Human nickel dichloride affects expression ISO Il18 (Rattus norvegicus) 6480464 nickel chloride affects the expression of IL18 mRNA CTD PMID:22546817 IL18 Human nickel dichloride affects expression ISO Il18 (Mus musculus) 6480464 nickel chloride affects the expression of IL18 mRNA CTD PMID:24670797 IL18 Human nickel sulfate decreases expression EXP 6480464 nickel sulfate results in decreased expression of IL18 mRNA CTD PMID:18651567 IL18 Human nickel sulfate increases expression EXP 6480464 nickel sulfate results in increased expression of IL18 protein CTD PMID:23063874 IL18 Human nicotinamide multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Streptozocin co-treated with Niacinamide co-treated with ENV-2 compound] results in decreased expression of IL18 mRNA CTD PMID:28322830 IL18 Human nicotine increases secretion EXP 6480464 Nicotine results in increased secretion of IL18 protein CTD PMID:35131329 IL18 Human nicotine multiple interactions EXP 6480464 CHRNA5 protein affects the reaction [Nicotine results in increased secretion of IL18 protein] CTD PMID:35131329 IL18 Human nifuroxazide multiple interactions ISO Il18 (Rattus norvegicus) 6480464 nifuroxazide inhibits the reaction [Streptozocin results in increased expression of IL18 mRNA] CTD PMID:29291386 IL18 Human nigericin multiple interactions EXP 6480464 [lipopolysaccharide more ... CTD PMID:29378952 IL18 Human nilotinib multiple interactions ISO Il18 (Mus musculus) 6480464 nilotinib inhibits the reaction [Folic Acid results in increased expression of IL18 protein] CTD PMID:31593741 IL18 Human nitrofen increases expression ISO Il18 (Rattus norvegicus) 6480464 nitrofen results in increased expression of IL18 mRNA CTD PMID:33484710 IL18 Human NMN zwitterion multiple interactions ISO Il18 (Mus musculus) 6480464 Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of IL18 protein] and Nicotinamide Mononucleotide inhibits the reaction [Zearalenone results in increased expression of IL18 mRNA] CTD PMID:30292833 and PMID:38159578 IL18 Human NMN zwitterion multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Nicotinamide Mononucleotide inhibits the reaction [Aluminum Chloride results in increased expression of IL18 protein] CTD PMID:30292833 IL18 Human Nonylphenol increases expression ISO Il18 (Rattus norvegicus) 6480464 nonylphenol results in increased expression of IL18 protein CTD PMID:35998786 IL18 Human Nonylphenol increases expression EXP 6480464 nonylphenol results in increased expression of IL18 protein CTD PMID:35998786 IL18 Human obeticholic acid multiple interactions ISO Il18 (Mus musculus) 6480464 obeticholic acid inhibits the reaction [Methamphetamine results in increased expression of IL18 mRNA] CTD PMID:35688268 IL18 Human ochratoxin A increases expression ISO Il18 (Mus musculus) 6480464 ochratoxin A results in increased expression of IL18 mRNA CTD PMID:33543323 IL18 Human ochratoxin A increases secretion EXP 6480464 ochratoxin A results in increased secretion of IL18 protein CTD PMID:38301823 IL18 Human oleic acid multiple interactions EXP 6480464 [perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of IL18 mRNA and [perfluorodecanoic acid co-treated with Oleic Acid] results in increased secretion of IL18 protein CTD PMID:36423729 IL18 Human olmesartan multiple interactions ISO Il18 (Rattus norvegicus) 6480464 olmesartan inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 IL18 Human oxaliplatin multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of IL18 mRNA CTD PMID:25729387 IL18 Human oxaliplatin increases expression ISO Il18 (Rattus norvegicus) 6480464 oxaliplatin results in increased expression of IL18 mRNA CTD PMID:25729387 IL18 Human ozone multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Ozone co-treated with Chlorine] results in decreased expression of IL18 mRNA CTD PMID:18636392 IL18 Human ozone increases expression ISO Il18 (Mus musculus) 6480464 Ozone results in increased expression of IL18 mRNA and Ozone results in increased expression of IL18 protein CTD PMID:32167222 and PMID:35928613 IL18 Human ozone increases expression ISO Il18 (Rattus norvegicus) 6480464 Ozone results in increased expression of IL18 protein CTD PMID:33383130 IL18 Human ozone multiple interactions EXP 6480464 [Air Pollutants results in increased abundance of Ozone] which results in increased expression of IL18 mRNA CTD PMID:22196529 IL18 Human ozone multiple interactions ISO Il18 (Mus musculus) 6480464 3-(4-t-butylphenyl)-N-(2 more ... CTD PMID:26731380 more ... IL18 Human ozone decreases expression ISO Il18 (Mus musculus) 6480464 Ozone results in decreased expression of IL18 mRNA CTD PMID:26342085 IL18 Human paclitaxel increases expression EXP 6480464 Paclitaxel results in increased expression of IL18 mRNA CTD PMID:31993881 IL18 Human paclitaxel multiple interactions EXP 6480464 [Cisplatin co-treated with Paclitaxel] results in increased expression of IL18 mRNA more ... CTD PMID:20705681 and PMID:31993881 IL18 Human paclitaxel increases secretion EXP 6480464 Paclitaxel results in increased secretion of IL18 protein CTD PMID:31993881 IL18 Human paeoniflorin multiple interactions ISO Il18 (Mus musculus) 6480464 peoniflorin inhibits the reaction [Particulate Matter results in increased expression of IL18 protein] CTD PMID:38705442 IL18 Human paeoniflorin multiple interactions EXP 6480464 2-(1 more ... CTD PMID:38705442 IL18 Human Palbinone multiple interactions ISO Il18 (Rattus norvegicus) 6480464 palbinone inhibits the reaction [Streptozocin results in increased expression of IL18 protein] CTD PMID:32202043 IL18 Human pamidronate multiple interactions ISO Il18 (Mus musculus) 6480464 [Pamidronate results in increased susceptibility to Acetylmuramyl-Alanyl-Isoglutamine] which results in increased secretion of IL18 protein CTD PMID:21282739 IL18 Human paracetamol affects expression ISO Il18 (Mus musculus) 6480464 Acetaminophen affects the expression of IL18 mRNA CTD PMID:17562736 IL18 Human paracetamol multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [boric acid results in increased abundance of Boron] inhibits the reaction [Acetaminophen results in increased expression of IL18 protein] and Acetylcysteine inhibits the reaction [Acetaminophen results in increased expression of IL18 protein] CTD PMID:35020164 IL18 Human paracetamol increases expression ISO Il18 (Rattus norvegicus) 6480464 Acetaminophen results in increased expression of IL18 protein CTD PMID:35020164 IL18 Human paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of IL18 mRNA CTD PMID:29067470 IL18 Human paracetamol decreases expression EXP 6480464 Acetaminophen results in decreased expression of IL18 mRNA CTD PMID:31059760 IL18 Human paracetamol multiple interactions EXP 6480464 [Acetaminophen co-treated with Lipopolysaccharides] affects the expression of IL18 mRNA CTD PMID:31059760 IL18 Human paracetamol increases expression ISO Il18 (Mus musculus) 6480464 Acetaminophen results in increased expression of IL18 mRNA and Acetaminophen results in increased expression of IL18 protein CTD PMID:17585979 more ... IL18 Human paracetamol multiple interactions ISO Il18 (Mus musculus) 6480464 Aspirin inhibits the reaction [Acetaminophen results in increased expression of IL18 mRNA] more ... CTD PMID:19164858 and PMID:20102673 IL18 Human paraquat increases expression EXP 6480464 Paraquat results in increased expression of IL18 mRNA CTD PMID:20883675 IL18 Human paraquat multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Glyburide inhibits the reaction [Paraquat results in increased expression of IL18 protein] more ... CTD PMID:25338942 and PMID:30025709 IL18 Human paraquat increases expression ISO Il18 (Rattus norvegicus) 6480464 Paraquat results in increased expression of IL18 mRNA and Paraquat results in increased expression of IL18 protein CTD PMID:25338942 and PMID:30025709 IL18 Human paraquat multiple interactions ISO Il18 (Mus musculus) 6480464 Glyburide inhibits the reaction [Paraquat results in increased secretion of IL18 protein] and Silymarin inhibits the reaction [Paraquat results in increased secretion of IL18 protein] CTD PMID:25338942 and PMID:29054699 IL18 Human paraquat increases secretion ISO Il18 (Mus musculus) 6480464 Paraquat results in increased secretion of IL18 protein CTD PMID:25338942 and PMID:29054699 IL18 Human patulin multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [Patulin results in increased expression of IL18 protein] CTD PMID:33217525 IL18 Human PD 0325901 multiple interactions EXP 6480464 mirdametinib inhibits the reaction [[IL15 protein co-treated with IL18 protein] results in increased secretion of IFNG protein] CTD PMID:27563819 IL18 Human pentachlorophenol increases expression EXP 6480464 Pentachlorophenol results in increased expression of IL18 mRNA CTD PMID:35550411 IL18 Human pentane-2,3-dione increases expression ISO Il18 (Rattus norvegicus) 6480464 2 and 3-pentanedione results in increased expression of IL18 mRNA CTD PMID:25710175 IL18 Human perfluorodecanoic acid increases secretion EXP 6480464 perfluorodecanoic acid results in increased secretion of IL18 protein CTD PMID:36423729 IL18 Human perfluorodecanoic acid multiple interactions EXP 6480464 [perfluorodecanoic acid co-treated with Oleic Acid] results in increased expression of IL18 mRNA and [perfluorodecanoic acid co-treated with Oleic Acid] results in increased secretion of IL18 protein CTD PMID:36423729 IL18 Human perfluorodecanoic acid increases expression EXP 6480464 perfluorodecanoic acid results in increased expression of IL18 mRNA CTD PMID:36423729 IL18 Human perfluorohexanesulfonic acid increases expression ISO Il18 (Mus musculus) 6480464 perfluorohexanesulfonic acid results in increased expression of IL18 mRNA CTD PMID:37995155 IL18 Human perfluorononanoic acid decreases expression EXP 6480464 perfluoro-n-nonanoic acid results in decreased expression of IL18 mRNA CTD PMID:38568856 IL18 Human perfluorooctane-1-sulfonic acid multiple interactions ISO Il18 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in decreased expression of IL18 mRNA and [perfluorooctane sulfonic acid co-treated with Pectins] results in decreased expression of IL18 mRNA CTD PMID:36331819 IL18 Human perfluorooctanoic acid multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Zeranol co-treated with perfluorooctanoic acid] results in decreased expression of IL18 mRNA CTD PMID:35163327 IL18 Human perfluoroundecanoic acid decreases expression EXP 6480464 perfluoroundecanoic acid results in decreased expression of IL18 protein CTD PMID:32916415 IL18 Human permethrin multiple interactions ISO Il18 (Mus musculus) 6480464 [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL18 protein and NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL18 protein] CTD PMID:32832901 IL18 Human phenethyl caffeate multiple interactions EXP 6480464 caffeic acid phenethyl ester inhibits the reaction [arsenite results in decreased expression of IL18 mRNA] CTD PMID:16085347 IL18 Human phenobarbital multiple interactions ISO Il18 (Mus musculus) 6480464 [AGT protein co-treated with Phenobarbital] affects the expression of IL18 protein and DAPK1 protein affects the reaction [[AGT protein co-treated with Phenobarbital] affects the expression of IL18 protein] CTD PMID:34796763 IL18 Human phenytoin multiple interactions ISO Il18 (Mus musculus) 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL18 mRNA CTD PMID:21224054 IL18 Human phosgene increases expression ISO Il18 (Rattus norvegicus) 6480464 Phosgene results in increased expression of IL18 protein CTD PMID:33012731 IL18 Human phosgene multiple interactions ISO Il18 (Rattus norvegicus) 6480464 NLRP3 protein promotes the reaction [Phosgene results in increased expression of IL18 protein] CTD PMID:33012731 IL18 Human phthalic anhydride increases activity ISO Il18 (Mus musculus) 6480464 phthalic anhydride results in increased activity of IL18 protein CTD PMID:15840424 IL18 Human Phytolaccoside E increases secretion EXP 6480464 esculentoside A results in increased secretion of IL18 protein CTD PMID:36460195 IL18 Human Phytolaccoside E increases expression ISO Il18 (Mus musculus) 6480464 esculentoside A results in increased expression of IL18 protein CTD PMID:36460195 IL18 Human pioglitazone multiple interactions ISO Il18 (Rattus norvegicus) 6480464 pioglitazone inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 IL18 Human pirinixic acid multiple interactions ISO Il18 (Mus musculus) 6480464 [pirinixic acid co-treated with PPARA] results in decreased expression of IL18 mRNA and PPARA protein affects the reaction [pirinixic acid results in decreased expression of IL18 mRNA] CTD PMID:17321000 and PMID:20813756 IL18 Human pirinixic acid decreases expression ISO Il18 (Mus musculus) 6480464 pirinixic acid results in decreased expression of IL18 mRNA CTD PMID:17321000 more ... IL18 Human prednisolone multiple interactions ISO Il18 (Mus musculus) 6480464 Prednisolone inhibits the reaction [Picryl Chloride results in increased expression of IL18 protein] CTD PMID:16442096 IL18 Human PRIM-O-GLUCOSYLCIMIFUGIN multiple interactions ISO Il18 (Mus musculus) 6480464 prim-O-glucosylcimifugin inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of and results in increased secretion of IL18 protein] and prim-O-glucosylcimifugin results in decreased expression of and results in decreased secretion of IL18 protein CTD PMID:36088791 IL18 Human procyanidin B2 multiple interactions ISO Il18 (Rattus norvegicus) 6480464 procyanidin B2 inhibits the reaction [Paraquat results in increased expression of IL18 mRNA] and procyanidin B2 inhibits the reaction [Paraquat results in increased expression of IL18 protein] CTD PMID:30025709 IL18 Human progesterone multiple interactions ISO Il18 (Mus musculus) 6480464 [fulvestrant co-treated with Mifepristone] inhibits the reaction [[Progesterone co-treated with Estrogens] inhibits the reaction [Lipopolysaccharides results in increased expression of IL18 mRNA]] more ... CTD PMID:17850464 IL18 Human propofol increases expression EXP 6480464 Propofol results in increased expression of IL18 mRNA CTD PMID:35953652 IL18 Human propofol multiple interactions EXP 6480464 Lipopolysaccharides promotes the reaction [Propofol results in increased expression of IL18 mRNA] CTD PMID:35953652 IL18 Human protein kinase inhibitor multiple interactions EXP 6480464 Protein Kinase Inhibitors inhibits the reaction [IL18 protein results in increased expression of IFNG protein] CTD PMID:28003376 IL18 Human pterostilbene multiple interactions EXP 6480464 pterostilbene inhibits the reaction [Ethanol results in increased expression of IL18 protein] and RIPK3 protein inhibits the reaction [pterostilbene inhibits the reaction [Ethanol results in increased expression of IL18 protein]] CTD PMID:34474091 IL18 Human puerarin multiple interactions EXP 6480464 PRKAA1 protein promotes the reaction [puerarin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL18 protein]] more ... CTD PMID:35331853 IL18 Human Pyridostigmine bromide multiple interactions ISO Il18 (Mus musculus) 6480464 [Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL18 protein and NLRP3 protein affects the reaction [[Pyridostigmine Bromide co-treated with Permethrin] results in increased expression of IL18 protein] CTD PMID:32832901 IL18 Human pyrrolidine dithiocarbamate multiple interactions ISO Il18 (Mus musculus) 6480464 pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of and results in increased secretion of IL18 protein] and pyrrolidine dithiocarbamic acid inhibits the reaction [Isoproterenol results in increased expression of IL18 mRNA] CTD PMID:15178407 IL18 Human quartz increases secretion ISO Il18 (Rattus norvegicus) 6480464 Quartz results in increased secretion of IL18 protein CTD PMID:32976597 IL18 Human quartz multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Tobacco Smoke Pollution promotes the reaction [Quartz results in increased secretion of IL18 protein] CTD PMID:32976597 IL18 Human quercetin multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Quercetin inhibits the reaction [Fructose results in increased expression of IL18 protein] and Quercetin inhibits the reaction [Streptozocin results in increased expression of IL18 protein] CTD PMID:22426011 and PMID:23647015 IL18 Human quercetin multiple interactions EXP 6480464 Quercetin inhibits the reaction [Lipopolysaccharides results in increased secretion of IL18 protein] more ... CTD PMID:34791735 IL18 Human rac-lactic acid decreases expression EXP 6480464 Lactic Acid results in decreased expression of IL18 mRNA CTD PMID:30851411 IL18 Human ranitidine multiple interactions EXP 6480464 Ranitidine inhibits the reaction [Cimetidine results in increased expression of IL18 protein] more ... CTD PMID:11752121 and PMID:16723495 IL18 Human reactive oxygen species increases abundance EXP 6480464 IL18 protein results in increased abundance of Reactive Oxygen Species CTD PMID:19561311 IL18 Human reactive oxygen species multiple interactions EXP 6480464 diphenyleneiodonium inhibits the reaction [IL18 protein results in increased abundance of Reactive Oxygen Species] and resveratrol inhibits the reaction [IL18 protein results in increased abundance of Reactive Oxygen Species] CTD PMID:19561311 IL18 Human Rebamipide increases expression ISO Il18 (Rattus norvegicus) 6480464 rebamipide results in increased expression of IL18 mRNA CTD PMID:18299717 IL18 Human reserpine increases expression ISO Il18 (Rattus norvegicus) 6480464 Reserpine results in increased expression of IL18 mRNA CTD PMID:8999896 IL18 Human resorcinol increases expression EXP 6480464 resorcinol results in increased expression of IL18 mRNA and resorcinol results in increased expression of IL18 protein CTD PMID:23063874 and PMID:30806763 IL18 Human resveratrol multiple interactions EXP 6480464 Resveratrol inhibits the reaction [BSG protein results in increased expression of and results in increased secretion of IL18 protein] more ... CTD PMID:19561311 and PMID:24149798 IL18 Human resveratrol multiple interactions ISO Il18 (Mus musculus) 6480464 Resveratrol inhibits the reaction [Aluminum Chloride results in increased expression of IL18 protein] CTD PMID:34614429 and PMID:35156769 IL18 Human resveratrol multiple interactions ISO Il18 (Rattus norvegicus) 6480464 resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL18 mRNA] and resveratrol inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency] results in increased expression of IL18 protein] CTD PMID:26464617 IL18 Human Rhein multiple interactions ISO Il18 (Mus musculus) 6480464 rhein inhibits the reaction [[Methionine deficiency co-treated with Choline deficiency] results in increased expression of IL18 protein] CTD PMID:37023836 IL18 Human rifampicin multiple interactions ISO Il18 (Mus musculus) 6480464 [Monocrotaline co-treated with Rifampin co-treated with Phenytoin co-treated with PRKDC] results in decreased expression of IL18 mRNA CTD PMID:21224054 IL18 Human rimonabant multiple interactions EXP 6480464 Rimonabant inhibits the reaction [Cannabidiol results in decreased expression of IL18 protein] CTD PMID:27932991 IL18 Human rolipram multiple interactions ISO Il18 (Mus musculus) 6480464 Rolipram inhibits the reaction [Picryl Chloride results in increased expression of IL18 protein] CTD PMID:16442096 IL18 Human rotenone decreases expression ISO Il18 (Rattus norvegicus) 6480464 Rotenone results in decreased expression of IL18 mRNA CTD PMID:28374803 IL18 Human rotenone multiple interactions EXP 6480464 Rotenone promotes the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased cleavage of IL18 protein] and Rotenone promotes the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein] CTD PMID:30205151 IL18 Human Ruscogenin multiple interactions EXP 6480464 ruscogenin inhibits the reaction [arsenite results in increased expression of and results in increased secretion of IL18 protein] CTD PMID:36343453 IL18 Human rutin multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Rutin inhibits the reaction [Fructose results in increased expression of IL18 protein] CTD PMID:22426011 IL18 Human rutin decreases expression ISO Il18 (Rattus norvegicus) 6480464 Rutin results in decreased expression of IL18 mRNA CTD PMID:28693884 IL18 Human Salidroside multiple interactions ISO Il18 (Mus musculus) 6480464 rhodioloside inhibits the reaction [furan results in increased expression of IL18 mRNA] and rhodioloside inhibits the reaction [furan results in increased expression of IL18 protein] CTD PMID:34450210 IL18 Human sarpogrelate decreases expression EXP 6480464 sarpogrelate results in decreased expression of IL18 protein CTD PMID:15080020 IL18 Human SB 203580 multiple interactions EXP 6480464 SB 203580 inhibits the reaction [IL18 protein results in increased expression of PTEN mRNA] more ... CTD PMID:18215737 IL18 Human scutellarin multiple interactions ISO Il18 (Rattus norvegicus) 6480464 scutellarin inhibits the reaction [Streptozocin results in increased expression of IL18 protein] CTD PMID:37081038 IL18 Human serpentine asbestos decreases expression EXP 6480464 Asbestos and Serpentine results in decreased expression of IL18 mRNA CTD PMID:24160326 IL18 Human sevoflurane multiple interactions ISO Il18 (Rattus norvegicus) 6480464 PHLDA1 protein promotes the reaction [Sevoflurane results in increased expression of IL18 protein] more ... CTD PMID:36047109 and PMID:36155068 IL18 Human sevoflurane increases expression EXP 6480464 Sevoflurane results in increased expression of IL18 mRNA CTD PMID:35953652 IL18 Human sevoflurane increases expression ISO Il18 (Rattus norvegicus) 6480464 Sevoflurane results in increased expression of IL18 mRNA and Sevoflurane results in increased expression of IL18 protein CTD PMID:36047109 and PMID:36155068 IL18 Human silicon dioxide increases expression EXP 6480464 Silicon Dioxide analog results in increased expression of IL18 mRNA and Silicon Dioxide results in increased expression of IL18 protein CTD PMID:23806026 and PMID:34766707 IL18 Human silicon dioxide increases secretion ISO Il18 (Mus musculus) 6480464 Silicon Dioxide analog results in increased secretion of IL18 protein CTD PMID:27311643 IL18 Human silicon dioxide multiple interactions ISO Il18 (Mus musculus) 6480464 3-(5-(2 more ... CTD PMID:27311643 IL18 Human silicon dioxide increases expression ISO Il18 (Rattus norvegicus) 6480464 Silicon Dioxide results in increased expression of IL18 mRNA CTD PMID:32721576 IL18 Human silver atom decreases expression ISO Il18 (Mus musculus) 6480464 Silver results in decreased expression of IL18 mRNA CTD PMID:27131904 IL18 Human silver(0) decreases expression ISO Il18 (Mus musculus) 6480464 Silver results in decreased expression of IL18 mRNA CTD PMID:27131904 IL18 Human simvastatin multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Mevalonic Acid inhibits the reaction [Simvastatin inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA]] and Simvastatin inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 IL18 Human simvastatin multiple interactions EXP 6480464 Simvastatin promotes the reaction [Lipopolysaccharides results in increased secretion of IL18 protein] CTD PMID:27377765 IL18 Human sirolimus multiple interactions EXP 6480464 Sirolimus inhibits the reaction [[Acrolein co-treated with Lipopolysaccharides] results in increased expression of IL18 protein] CTD PMID:30205151 IL18 Human sirolimus multiple interactions ISO Il18 (Mus musculus) 6480464 Sirolimus inhibits the reaction [Particulate Matter results in increased expression of IL18 protein] CTD PMID:38237716 IL18 Human sodium arsenite decreases expression ISO Il18 (Mus musculus) 6480464 sodium arsenite results in decreased expression of IL18 mRNA CTD PMID:21911445 IL18 Human sodium arsenite increases expression ISO Il18 (Mus musculus) 6480464 sodium arsenite results in increased expression of IL18 mRNA CTD PMID:37682722 IL18 Human sodium arsenite multiple interactions EXP 6480464 [lipopolysaccharide more ... CTD PMID:34920032 IL18 Human sodium arsenite increases expression ISO Il18 (Rattus norvegicus) 6480464 sodium arsenite results in increased expression of IL18 protein CTD PMID:32593899 more ... IL18 Human sodium dichromate increases expression ISO Il18 (Rattus norvegicus) 6480464 sodium bichromate results in increased expression of IL18 mRNA CTD PMID:22561333 IL18 Human Soman increases expression ISO Il18 (Rattus norvegicus) 6480464 Soman results in increased expression of IL18 mRNA CTD PMID:19281266 IL18 Human sphingosine 1-phosphate multiple interactions ISO Il18 (Rattus norvegicus) 6480464 3-methyladenine inhibits the reaction [sphingosine 1-phosphate results in increased expression of IL18 protein] more ... CTD PMID:37169277 IL18 Human spironolactone multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Spironolactone inhibits the reaction [Aldosterone results in increased expression of IL18 mRNA] CTD PMID:18660453 IL18 Human sterigmatocystin increases expression ISO Il18 (Mus musculus) 6480464 Sterigmatocystin results in increased expression of IL18 mRNA CTD PMID:19818335 IL18 Human streptozocin increases expression ISO Il18 (Rattus norvegicus) 6480464 Streptozocin results in increased expression of IL18 mRNA and Streptozocin results in increased expression of IL18 protein CTD PMID:23647015 more ... IL18 Human streptozocin multiple interactions ISO Il18 (Mus musculus) 6480464 [Dietary Fats co-treated with Streptozocin] results in increased expression of and results in increased secretion of IL18 protein more ... CTD PMID:34212273 more ... IL18 Human streptozocin increases expression ISO Il18 (Mus musculus) 6480464 Streptozocin results in increased expression of IL18 mRNA and Streptozocin results in increased expression of IL18 protein CTD PMID:34212273 IL18 Human streptozocin multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Streptozocin co-treated with Niacinamide co-treated with ENV-2 compound] results in decreased expression of IL18 mRNA more ... CTD PMID:23647015 more ... IL18 Human sulfamic acid increases expression EXP 6480464 sulfamic acid results in increased expression of IL18 protein CTD PMID:23063874 IL18 Human sulfasalazine multiple interactions ISO Il18 (Rattus norvegicus) 6480464 Sulfasalazine inhibits the reaction [Acetic Acid results in increased expression of IL18 protein] CTD PMID:35595039 IL18 Human sulfur dioxide increases expression ISO Il18 (Rattus norvegicus) 6480464 Sulfur Dioxide results in increased expression of IL18 protein CTD PMID:27565714 IL18 Human tetrachloromethane decreases expression ISO Il18 (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of IL18 mRNA CTD PMID:27339419 and PMID:31919559 IL18 Human thalidomide increases expression ISO Il18 (Mus musculus) 6480464 Thalidomide results in increased expression of IL18 CTD PMID:17089043 IL18 Human thapsigargin increases expression EXP 6480464 Thapsigargin results in increased expression of IL18 mRNA CTD PMID:30796460 IL18 Human theophylline multiple interactions EXP 6480464 Theophylline inhibits the reaction [Hydrogen Peroxide inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein]]] and Theophylline inhibits the reaction [Tobacco Smoke Pollution inhibits the reaction [Dexamethasone inhibits the reaction [TNF protein results in increased secretion of IL18 protein]]] CTD PMID:18951874 IL18 Human thioacetamide increases expression ISO Il18 (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of IL18 mRNA CTD PMID:34492290 IL18 Human thiram increases expression EXP 6480464 Thiram results in increased expression of IL18 protein CTD PMID:23063874 IL18 Human tipifarnib multiple interactions ISO Il18 (Mus musculus) 6480464 geraniol promotes the reaction [tipifarnib inhibits the reaction [[Alendronate co-treated with Lovastatin co-treated with lipopolysaccharide more ... CTD PMID:21430599 IL18 Human titanium dioxide multiple interactions ISO Il18 (Mus musculus) 6480464 [titanium dioxide co-treated with Azoxymethane co-treated with Dextran Sulfate] results in increased expression of IL18 mRNA CTD PMID:29950665 IL18 Human TMC-120A increases expression ISO Il18 (Mus musculus) 6480464 TMC 120A results in increased expression of IL18 mRNA CTD PMID:19818335 IL18 Human toluene 2,4-diisocyanate increases expression ISO Il18 (Mus musculus) 6480464 Toluene 2 and 4-Diisocyanate results in increased expression of IL18 protein CTD PMID:31070765 IL18 Human toluene 2,4-diisocyanate increases secretion ISO Il18 (Mus musculus) 6480464 Toluene 2 and 4-Diisocyanate results in increased secretion of IL18 protein CTD PMID:30517707 and PMID:33711354 IL18 Human toluene 2,4-diisocyanate multiple interactions ISO Il18 (Mus musculus) 6480464 2-(1 more ... CTD PMID:30517707 more ... IL18 Human topotecan multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of IL18 mRNA CTD PMID:25729387 IL18 Human topotecan increases expression ISO Il18 (Rattus norvegicus) 6480464 Topotecan results in increased expression of IL18 mRNA CTD PMID:25729387 IL18 Human trans-isoeugenol increases expression EXP 6480464 isoeugenol results in increased expression of IL18 protein CTD PMID:23063874 IL18 Human tributylstannane multiple interactions EXP 6480464 [tributyltin co-treated with LHB protein] results in increased secretion of IL18 protein CTD PMID:38630605 IL18 Human trichostatin A increases expression EXP 6480464 trichostatin A results in increased expression of IL18 mRNA CTD PMID:24935251 IL18 Human triphenyl phosphate affects expression EXP 6480464 triphenyl phosphate affects the expression of IL18 mRNA CTD PMID:37042841 IL18 Human Triptolide decreases expression ISO Il18 (Mus musculus) 6480464 triptolide results in decreased expression of IL18 mRNA CTD PMID:32835833 IL18 Human Triptolide multiple interactions ISO Il18 (Mus musculus) 6480464 [triptolide co-treated with Lipopolysaccharides] results in increased expression of IL18 mRNA and [triptolide co-treated with Lipopolysaccharides] results in increased secretion of IL18 protein CTD PMID:36328986 IL18 Human trovafloxacin multiple interactions ISO Il18 (Mus musculus) 6480464 IL18 protein results in increased susceptibility to [trovafloxacin co-treated with lipopolysaccharide more ... CTD PMID:18930950 and PMID:19638433 IL18 Human tungsten multiple interactions ISO Il18 (Rattus norvegicus) 6480464 [Nickel co-treated with Cobalt co-treated with Tungsten] results in decreased expression of IL18 mRNA CTD PMID:22198552 IL18 Human tunicamycin increases secretion ISO Il18 (Rattus norvegicus) 6480464 Tunicamycin results in increased secretion of IL18 protein CTD PMID:37654027 IL18 Human ubiquinone-0 multiple interactions EXP 6480464 ubiquinone-O inhibits the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased expression of IL18 protein] CTD PMID:36847822 IL18 Human ubiquinone-0 decreases expression EXP 6480464 ubiquinone-O results in decreased expression of IL18 protein CTD PMID:36847822 IL18 Human undecan-2-one multiple interactions ISO Il18 (Mus musculus) 6480464 undecan-2-one inhibits the reaction [Particulate Matter results in increased expression of IL18 protein] CTD PMID:35285579 IL18 Human uranium atom decreases secretion ISO Il18 (Mus musculus) 6480464 Uranium results in decreased secretion of IL18 protein CTD PMID:23659960 IL18 Human usnic acid multiple interactions EXP 6480464 [usnic acid co-treated with Lipopolysaccharides] results in increased expression of IL18 mRNA CTD PMID:22777745 IL18 Human valproic acid affects expression ISO Il18 (Mus musculus) 6480464 Valproic Acid affects the expression of IL18 mRNA CTD PMID:20421339 IL18 Human valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of IL18 mRNA CTD PMID:23179753 IL18 Human vancomycin multiple interactions ISO Il18 (Mus musculus) 6480464 [Neomycin co-treated with Metronidazole co-treated with Ampicillin co-treated with Vancomycin] inhibits the reaction [Methamphetamine results in increased secretion of IL18 protein] CTD PMID:35390362 IL18 Human vanillin multiple interactions ISO Il18 (Rattus norvegicus) 6480464 vanillin inhibits the reaction [Cisplatin results in increased expression of IL18 protein] and vanillin inhibits the reaction [Methotrexate results in increased expression of IL18 protein] CTD PMID:29216766 IL18 Human vinclozolin decreases expression ISO Il18 (Rattus norvegicus) 6480464 vinclozolin results in decreased expression of IL18 mRNA CTD PMID:18629315 IL18 Human vinclozolin affects expression ISO Il18 (Rattus norvegicus) 6480464 vinclozolin affects the expression of IL18 mRNA CTD PMID:19015723 IL18 Human vorinostat decreases expression EXP 6480464 vorinostat results in decreased expression of IL18 protein CTD PMID:17593366 IL18 Human wortmannin multiple interactions ISO Il18 (Mus musculus) 6480464 wortmannin inhibits the reaction [Isoproterenol results in increased secretion of IL18 protein] CTD PMID:15178407 IL18 Human zearalenone increases secretion ISO Il18 (Mus musculus) 6480464 Zearalenone results in increased secretion of IL18 protein CTD PMID:30270565 IL18 Human zearalenone multiple interactions ISO Il18 (Mus musculus) 6480464 [Dextran Sulfate co-treated with Zearalenone] results in increased expression of IL18 mRNA more ... CTD PMID:30270565 and PMID:38159578 IL18 Human zearalenone increases expression ISO Il18 (Mus musculus) 6480464 Zearalenone results in increased expression of IL18 mRNA CTD PMID:30270565 and PMID:38159578 IL18 Human zinc protoporphyrin multiple interactions EXP 6480464 zinc protoporphyrin inhibits the reaction [Dexmedetomidine inhibits the reaction [Ropivacaine results in increased expression of IL18 protein]] and zinc protoporphyrin inhibits the reaction [Hemin results in decreased susceptibility to IL18 protein] CTD PMID:18215737 and PMID:36858639 IL18 Human zirconium atom increases expression EXP 6480464 Zirconium results in increased expression of IL18 protein CTD PMID:16100009
