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Gene: DYNLL1 (dynein light chain LC8-type 1) Homo sapiens
Symbol: DYNLL1
Name: dynein light chain LC8-type 1
RGD ID: 731010
Description: Predicted to have several functions, including dynein intermediate chain binding activity; dynein light intermediate chain binding activity; and protein C-terminus binding activity. Involved in negative regulation of phosphorylation. Localizes to several cellular components, including kinetochore; microtubule cytoskeleton; and nucleus. Colocalizes with COP9 signalosome.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: 8 kDa dynein light chain; cytoplasmic dynein light polypeptide; DLC1; DLC8; DNCL1; DNCLC1; dynein light chain 1, cytoplasmic; dynein, cytoplasmic, light polypeptide 1; dynein, light chain, LC8-type 1; hdlc1; LC8; LC8a; MGC126137; MGC126138; PIN; protein inhibitor of neuronal nitric oxide synthase
Mus musculus (house mouse) : Dynll1 (dynein light chain LC8-type 1)  MGI  Alliance
Rattus norvegicus (Norway rat) : Dynll1 (dynein light chain LC8-type 1)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Dynll1 (dynein light chain LC8-type 1)
Pan paniscus (bonobo/pygmy chimpanzee) : DYNLL1 (dynein light chain LC8-type 1)
Canis lupus familiaris (dog) : DYNLL1 (dynein light chain LC8-type 1)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Dynll1 (dynein light chain LC8-type 1)
Sus scrofa (pig) : DYNLL1 (dynein light chain LC8-type 1)
Chlorocebus sabaeus (African green monkey) : DYNLL1 (dynein light chain LC8-type 1)
Heterocephalus glaber (naked mole-rat) : Dynll1 (dynein light chain LC8-type 1)
more info ...
Related Pseudogenes: DYNLL1P1   DYNLL1P2   DYNLL1P3   DYNLL1P4   DYNLL1P5   DYNLL1P6   DYNLL1P7  
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
NCBI Annotation Information: Note: DLC1 (Gene ID: 10395) and DYNLL1 (Gene ID: 8655) share the DLC1 symbol/alias in common. DLC1 is sometimes used as an alternative name for dynein light chain LC8-type 1 (DYNLL1), which can be confused with the official symbol for DLC1 Rho GTPase activating protein (DLC1). [05 Jul 2018]
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl12120,469,850 - 120,498,493 (+)EnsemblGRCh38hg38GRCh38
GRCh3812120,469,842 - 120,498,493 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh3712120,907,660 - 120,936,298 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 3612119,392,043 - 119,420,681 (+)NCBINCBI36hg18NCBI36
Build 3412119,396,652 - 119,399,010NCBI
Celera12120,542,375 - 120,570,391 (+)NCBI
Cytogenetic Map12q24.31NCBI
HuRef12117,917,550 - 117,946,088 (+)NCBIHuRef
CHM1_112120,876,465 - 120,905,100 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on DYNLL1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731010
Created: 2003-12-10
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.