Gene: KCNMB1 (potassium calcium-activated channel subfamily M regulatory beta subunit 1) Homo sapiens
Symbol: KCNMB1
Name: potassium calcium-activated channel subfamily M regulatory beta subunit 1
Description: MaxiK channels are large conductance, voltage and calcium-sensitive potassium channels which are fundamental to the control of smooth muscle tone and neuronal excitability. MaxiK channels can be formed by 2 subunits: the pore-forming alpha subunit and the product of this gene, the modulatory beta subunit. Intracellular calcium regulates the physical association between the alpha and beta subunits. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: big potassium channel beta subunit 1; BK channel beta subunit; BK channel beta subunit 1; BK channel subunit beta-1; BKbeta; BKbeta1; calcium-activated potassium channel subunit beta; calcium-activated potassium channel subunit beta-1; calcium-activated potassium channel, subfamily M subunit beta-1; charybdotoxin receptor subunit beta-1; hbeta1; hslo-beta; K(VCA)beta; k(VCA)beta-1; large conductance Ca2+-activated K+ channel beta 1 subunit; Maxi K channel beta subunit; maxi K channel subunit beta-1; MaxiK channel beta-subunit 1; OTTHUMP00000160996; potassium channel subfamily M regulatory beta subunit 1; potassium large conductance calcium-activated channel, subfamily M, beta member 1; SLO-BETA; slo-beta-1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh385170,378,161 - 170,389,677 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh375169,805,165 - 169,816,681 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 365169,737,745 - 169,749,216 (-)NCBINCBI36hg18NCBI36
Build 345169,737,744 - 169,749,216NCBI
Celera5165,837,099 - 165,848,570 (-)NCBI
Cytogenetic Map5q35.1NCBI
HuRef5164,904,047 - 164,915,563 (-)NCBIHuRef
CHM1_15169,238,046 - 169,249,557 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
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References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KCNMB1
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733456
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2018-02-06
Status: ACTIVE