Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: KCNJ8 (potassium inwardly rectifying channel subfamily J member 8) Homo sapiens
Symbol: KCNJ8
Name: potassium inwardly rectifying channel subfamily J member 8
Description: Potassium channels are present in most mammalian cells, where they participate in a wide range of physiologic responses. The protein encoded by this gene is an integral membrane protein and inward-rectifier type potassium channel. The encoded protein, which has a greater tendency to allow potassium to flow into a cell rather than out of a cell, is controlled by G-proteins. Defects in this gene may be a cause of J-wave syndromes and sudden infant death syndrome (SIDS). [provided by RefSeq, May 2012]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: ATP-sensitive inward rectifier potassium channel 8; inward rectifier K(+) channel Kir6.1; inwardly rectifying potassium channel KIR6.1; KIR6.1; potassium channel, inwardly rectifying subfamily J member 8; potassium channel, inwardly rectifying subfamily J, member 8; potassium inwardly-rectifying channel, subfamily J, member 8; potassium voltage-gated channel subfamily J member 8; uKATP-1
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381221,764,955 - 21,775,593 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371221,917,889 - 21,928,436 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361221,809,156 - 21,819,014 (-)NCBINCBI36hg18NCBI36
Build 341221,809,155 - 21,819,014NCBI
Celera1227,072,901 - 27,082,758 (-)NCBI
Cytogenetic Map12p12.1NCBI
HuRef1221,691,442 - 21,701,306 (-)NCBIHuRef
CHM1_11221,883,171 - 21,893,034 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on KCNJ8
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731904
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-09-12
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.