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Gene: CLCNKB (chloride voltage-gated channel Kb) Homo sapiens
Symbol: CLCNKB
Name: chloride voltage-gated channel Kb
RGD ID: 736095
Description: Predicted to have voltage-gated chloride channel activity. Predicted to be involved in chloride transport. Predicted to localize to integral component of plasma membrane. Implicated in Bartter disease type 3; Bartter disease type 4b; Gitelman syndrome; and hypertension.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: chloride channel Kb; chloride channel protein ClC-Kb; chloride channel, kidney, B; chloride channel, voltage-sensitive Kb; ClC-K2; ClC-Kb; CLCKB; hClC-Kb; MGC24087
Mus musculus (house mouse) : Clcnkb (chloride channel, voltage-sensitive Kb)  MGI  Alliance
Rattus norvegicus (Norway rat) : Clcnkb (chloride voltage-gated channel Kb)  Alliance
Pan paniscus (bonobo/pygmy chimpanzee) : CLCNKB (chloride voltage-gated channel Kb)
Canis lupus familiaris (dog) : CLCNKA (chloride voltage-gated channel Ka)
Chlorocebus sabaeus (African green monkey) : CLCNKB (chloride voltage-gated channel Kb)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38.p13 Ensembl116,043,736 - 16,057,308 (+)EnsemblGRCh38hg38GRCh38
GRCh38116,043,782 - 16,057,326 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37116,370,231 - 16,383,821 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36116,242,834 - 16,256,390 (+)NCBINCBI36hg18NCBI36
Build 34116,115,657 - 16,128,782NCBI
Celera114,850,148 - 14,863,702 (+)NCBI
Cytogenetic Map1p36.13NCBI
HuRef114,890,406 - 14,902,282 (+)NCBIHuRef
CHM1_1116,168,758 - 16,182,434 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on CLCNKB
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736095
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-09-16
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.