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Gene: PRKCE (protein kinase C epsilon) Homo sapiens
Symbol: PRKCE
Name: protein kinase C epsilon
Description: Exhibits enzyme activator activity; enzyme binding activity; and protein kinase C activity. Involved in several processes, including peptidyl-serine phosphorylation; positive regulation of cellular glucuronidation; and positive regulation of epithelial cell migration. Localizes to cytosol; endoplasmic reticulum; and plasma membrane. Predicted to colocalize with Golgi apparatus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC125656; MGC125657; nPKC-epsilon; PKCE; protein kinase C epsilon type
Mus musculus (house mouse) : Prkce (protein kinase C, epsilon)  MGI  Alliance
Rattus norvegicus (Norway rat) : Prkce (protein kinase C, epsilon)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Prkce (protein kinase C epsilon)
Pan paniscus (bonobo/pygmy chimpanzee) : PRKCE (protein kinase C epsilon)
Canis lupus familiaris (dog) : PRKCE (protein kinase C epsilon)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Prkce (protein kinase C epsilon)
Sus scrofa (pig) : PRKCE (protein kinase C epsilon)
Chlorocebus sabaeus (African green monkey) : PRKCE (protein kinase C epsilon)
Heterocephalus glaber (naked mole-rat) : Prkce (protein kinase C epsilon)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl245,651,345 - 46,187,990 (+)EnsemblGRCh38hg38GRCh38
GRCh38245,651,315 - 46,187,990 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37245,878,454 - 46,415,129 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36245,732,547 - 46,268,633 (+)NCBINCBI36hg18NCBI36
Build 34245,790,693 - 46,326,779NCBI
Celera245,717,245 - 46,253,470 (+)NCBI
Cytogenetic Map2p21NCBI
HuRef245,617,217 - 46,153,158 (+)NCBIHuRef
CHM1_1245,810,047 - 46,345,904 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on PRKCE
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 736442
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-03-31
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.