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Gene: AR (androgen receptor) Homo sapiens
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Symbol: AR
Name: androgen receptor
Description: Exhibits several functions, including ATPase binding activity; DNA-binding transcription factor activity, RNA polymerase II-specific; and transcription factor binding activity. Involved in several processes, including androgen receptor signaling pathway; negative regulation of extrinsic apoptotic signaling pathway; and regulation of macromolecule biosynthetic process. Localizes to the cytoplasm; nuclear lumen; and protein-containing complex. Implicated in several diseases, including androgen insensitivity syndrome; attention deficit hyperactivity disorder; conduct disorder; reproductive organ cancer (multiple); and spinal muscular atrophy (multiple). Biomarker of ductal carcinoma in situ; hypospadias; invasive ductal carcinoma; and prostate cancer.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AIS; androgen nuclear receptor variant 2; androgen receptor splice variant 4b; AR8; DHTR; dihydrotestosterone receptor; HUMARA; HYSP1; KD; Kennedy disease; NR3C4; nuclear receptor subfamily 3 group C member 4; SBMA; SMAX1; spinal and bulbar muscular atrophy; testicular feminization; TFM
Orthologs:
Mus musculus (house mouse) : Ar (androgen receptor)  MGI  Alliance
Rattus norvegicus (Norway rat) : Ar (androgen receptor)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Ar (androgen receptor)
Pan paniscus (bonobo/pygmy chimpanzee) : AR (androgen receptor)
Canis lupus familiaris (dog) : AR (androgen receptor)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Ar (androgen receptor)
Sus scrofa (pig) : AR (androgen receptor)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38X67,544,021 - 67,730,619 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37X66,763,874 - 66,950,461 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36X66,680,599 - 66,860,844 (+)NCBINCBI36hg18NCBI36
Build 34X66,571,703 - 66,727,140NCBI
CeleraX67,112,960 - 67,293,967 (+)NCBI
Cytogenetic MapXq12NCBI
HuRefX60,592,006 - 60,778,929 (+)NCBIHuRef
CHM1_1X66,656,369 - 66,842,989 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations