TAF1C (TATA-box binding protein associated factor, RNA polymerase I subunit C) - Rat Genome Database
Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: TAF1C (TATA-box binding protein associated factor, RNA polymerase I subunit C) Homo sapiens
Analyze
Symbol: TAF1C
Name: TATA-box binding protein associated factor, RNA polymerase I subunit C
RGD ID: 1313816
Description: Exhibits RNA polymerase I core promoter sequence-specific DNA binding activity and RNA polymerase I general transcription initiation factor activity. Predicted to be involved in positive regulation of gene expression, epigenetic and transcription, DNA-templated. Localizes to fibrillar center and nucleoplasm.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: MGC:39976; RNA polymerase I-specific TBP-associated factor 110 kDa; SL1; SL1, 110kD subunit; TAFI110; TAFI95; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kD; TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa; TATA box binding protein associated factor 1C; TATA box-binding protein-associated factor 1C; TATA box-binding protein-associated factor RNA polymerase I subunit C; TATA-box binding protein associated factor, RNA polymerase I, C; TBP-associated factor 1C; transcription factor SL1; transcription initiation factor SL1/TIF-IB subunit C
Orthologs:
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1684,177,847 - 84,187,070 (-)EnsemblGRCh38hg38GRCh38
GRCh381684,177,852 - 84,187,065 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371684,211,453 - 84,220,676 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361682,768,962 - 82,778,163 (-)NCBINCBI36hg18NCBI36
Build 341682,768,962 - 82,778,163NCBI
Celera1668,513,270 - 68,522,472 (-)NCBI
Cytogenetic Map16q24.1NCBI
HuRef1669,965,230 - 69,974,453 (-)NCBIHuRef
CHM1_11685,622,840 - 85,632,064 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations     Click to see Annotation Detail View

Molecular Pathway Annotations     Click to see Annotation Detail View
References

Additional References at PubMed
PMID:7801123   PMID:9050847   PMID:9582279   PMID:10894955   PMID:10913176   PMID:11250901   PMID:11250903   PMID:11698641   PMID:12107410   PMID:12393749   PMID:12477932   PMID:12498690  
PMID:12646563   PMID:14702039   PMID:15226435   PMID:15489334   PMID:15723054   PMID:15970593   PMID:16055704   PMID:16344560   PMID:17268553   PMID:17318177   PMID:19615732   PMID:20663923  
PMID:20800603   PMID:21873635   PMID:21900206   PMID:22368283   PMID:22589738   PMID:22843504   PMID:25551296   PMID:26023773   PMID:26186194   PMID:26496610   PMID:28514442   PMID:29467282  
PMID:29509190   PMID:30804502   PMID:30862715   PMID:31039436   PMID:31527615   PMID:31753913  


Genomics

Comparative Map Data
TAF1C
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1684,177,847 - 84,187,070 (-)EnsemblGRCh38hg38GRCh38
GRCh381684,177,852 - 84,187,065 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371684,211,453 - 84,220,676 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361682,768,962 - 82,778,163 (-)NCBINCBI36hg18NCBI36
Build 341682,768,962 - 82,778,163NCBI
Celera1668,513,270 - 68,522,472 (-)NCBI
Cytogenetic Map16q24.1NCBI
HuRef1669,965,230 - 69,974,453 (-)NCBIHuRef
CHM1_11685,622,840 - 85,632,064 (-)NCBICHM1_1
Taf1c
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm398120,324,713 - 120,331,945 (-)NCBI
GRCm388119,597,974 - 119,605,206 (-)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl8119,597,871 - 119,605,222 (-)EnsemblGRCm38mm10GRCm38
MGSCv378122,121,874 - 122,129,140 (-)NCBIGRCm37mm9NCBIm37
MGSCv368122,483,951 - 122,491,160 (-)NCBImm8
Celera8123,815,454 - 123,822,720 (-)NCBICelera
Cytogenetic Map8E1NCBI
Taf1c
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.01952,246,061 - 52,252,642 (-)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl1952,246,068 - 52,252,587 (-)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.01962,994,275 - 63,000,801 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.41949,842,371 - 49,848,891 (-)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.11949,851,555 - 49,853,756 (-)NCBI
Celera1946,911,512 - 46,918,032 (-)NCBICelera
Cytogenetic Map19q12NCBI
Taf1c
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_00495556487,452 - 134,650 (+)EnsemblChiLan1.0
ChiLan1.0NW_004955564121,988 - 132,347 (+)NCBIChiLan1.0ChiLan1.0
TAF1C
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11684,184,928 - 84,194,147 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl1684,184,928 - 84,194,147 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v01664,843,197 - 64,852,408 (-)NCBIMhudiblu_PPA_v0panPan3
TAF1C
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1 Ensembl568,175,014 - 68,184,277 (+)EnsemblCanFam3.1canFam3CanFam3.1
CanFam3.1568,175,196 - 68,184,267 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Taf1c
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366413,649,177 - 3,653,798 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
TAF1C
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl64,448,780 - 4,457,499 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.164,448,672 - 4,457,109 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.265,030,498 - 5,038,769 (+)NCBISscrofa10.2Sscrofa10.2susScr3
TAF1C
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl569,587,769 - 69,593,814 (-)Ensembl
ChlSab1.1569,587,592 - 69,596,312 (-)NCBI
Taf1c
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046247463,403,122 - 3,412,709 (+)NCBI

Position Markers
RH69603  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371684,211,365 - 84,211,512UniSTSGRCh37
Build 361682,768,866 - 82,769,013RGDNCBI36
Celera1668,513,174 - 68,513,321RGD
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map16q24UniSTS
HuRef1669,965,142 - 69,965,289UniSTS
GeneMap99-GB4 RH Map16464.87UniSTS
NCBI RH Map16655.8UniSTS
RH65170  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371684,219,307 - 84,219,547UniSTSGRCh37
Build 361682,776,808 - 82,777,048RGDNCBI36
Celera1668,521,117 - 68,521,357RGD
Cytogenetic Map16q24UniSTS
HuRef1669,973,084 - 69,973,324UniSTS
RH17650  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371684,211,646 - 84,211,867UniSTSGRCh37
Build 361682,769,147 - 82,769,368RGDNCBI36
Celera1668,513,455 - 68,513,676RGD
Cytogenetic Map16q24.1UniSTS
Cytogenetic Map16q24UniSTS
HuRef1669,965,423 - 69,965,644UniSTS
GeneMap99-GB4 RH Map16464.87UniSTS
NCBI RH Map16655.8UniSTS
SHGC-60617  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371684,212,265 - 84,212,466UniSTSGRCh37
Build 361682,769,766 - 82,769,967RGDNCBI36
Celera1668,514,074 - 68,514,275RGD
Cytogenetic Map16q24UniSTS
HuRef1669,966,042 - 69,966,243UniSTS
GeneMap99-GB4 RH Map16464.81UniSTS
Whitehead-RH Map16329.9UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:9895
Count of miRNA genes:1226
Interacting mature miRNAs:1606
Transcripts:ENST00000341690, ENST00000378541, ENST00000537450, ENST00000541676, ENST00000544090, ENST00000561955, ENST00000562330, ENST00000562445, ENST00000563428, ENST00000564208, ENST00000564345, ENST00000564454, ENST00000564774, ENST00000565279, ENST00000565544, ENST00000566183, ENST00000566732, ENST00000566903, ENST00000567759, ENST00000568265, ENST00000569505, ENST00000569609, ENST00000570117, ENST00000570270
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 2420 2596 1615 521 1586 363 4167 1938 3341 349 1437 1579 172 1204 2608 5 1
Low 19 395 111 103 363 102 190 259 393 70 23 34 2 1 180 1 1
Below cutoff 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NM_001243156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001243157 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001243158 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001243159 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001243160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_005679 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_139353 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005256226 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_005256227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006721325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_006721326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017023845 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017023846 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_017023847 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB209594 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AC009123 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK097031 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK299060 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK299347 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK304261 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK304739 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315982 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AU130229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY158985 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC028131 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CA397963 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471114 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC376588 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DC377529 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HI574118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  HI574120 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L39059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000341690   ⟹   ENSP00000345305
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,177,852 - 84,187,049 (-)Ensembl
RefSeq Acc Id: ENST00000537450
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,181,496 - 84,186,989 (-)Ensembl
RefSeq Acc Id: ENST00000541676   ⟹   ENSP00000437900
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,177,847 - 84,187,070 (-)Ensembl
RefSeq Acc Id: ENST00000544090
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,178,749 - 84,187,039 (-)Ensembl
RefSeq Acc Id: ENST00000561955   ⟹   ENSP00000456011
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,182,267 - 84,187,039 (-)Ensembl
RefSeq Acc Id: ENST00000562330
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,182,032 - 84,185,052 (-)Ensembl
RefSeq Acc Id: ENST00000562445
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,181,290 - 84,181,758 (-)Ensembl
RefSeq Acc Id: ENST00000563428   ⟹   ENSP00000455787
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,178,781 - 84,187,033 (-)Ensembl
RefSeq Acc Id: ENST00000564208
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,177,854 - 84,187,052 (-)Ensembl
RefSeq Acc Id: ENST00000564345   ⟹   ENSP00000454854
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,183,120 - 84,187,063 (-)Ensembl
RefSeq Acc Id: ENST00000564454   ⟹   ENSP00000457883
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,183,267 - 84,187,045 (-)Ensembl
RefSeq Acc Id: ENST00000564774
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,177,854 - 84,187,020 (-)Ensembl
RefSeq Acc Id: ENST00000565279
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,182,147 - 84,187,038 (-)Ensembl
RefSeq Acc Id: ENST00000565544
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,185,158 - 84,187,052 (-)Ensembl
RefSeq Acc Id: ENST00000566183
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,183,273 - 84,183,751 (-)Ensembl
RefSeq Acc Id: ENST00000566732   ⟹   ENSP00000455933
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,178,712 - 84,187,039 (-)Ensembl
RefSeq Acc Id: ENST00000566903   ⟹   ENSP00000456133
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,177,877 - 84,186,981 (-)Ensembl
RefSeq Acc Id: ENST00000567759   ⟹   ENSP00000455265
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,177,855 - 84,187,011 (-)Ensembl
RefSeq Acc Id: ENST00000568265   ⟹   ENSP00000456101
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,179,122 - 84,181,418 (-)Ensembl
RefSeq Acc Id: ENST00000569505   ⟹   ENSP00000457281
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,182,336 - 84,187,020 (-)Ensembl
RefSeq Acc Id: ENST00000569609   ⟹   ENSP00000454494
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,183,138 - 84,187,045 (-)Ensembl
RefSeq Acc Id: ENST00000570117   ⟹   ENSP00000455247
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,178,848 - 84,187,057 (-)Ensembl
RefSeq Acc Id: ENST00000570270
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1684,181,370 - 84,182,176 (-)Ensembl
RefSeq Acc Id: NM_001243156   ⟹   NP_001230085
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381684,177,855 - 84,187,057 (-)NCBI
GRCh371684,211,453 - 84,220,676 (-)NCBI
HuRef1669,965,230 - 69,974,453 (-)NCBI
CHM1_11685,622,840 - 85,632,064 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001243157   ⟹   NP_001230086
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381684,177,855 - 84,187,057 (-)NCBI
GRCh371684,211,453 - 84,220,676 (-)NCBI
HuRef1669,965,230 - 69,974,453 (-)NCBI
CHM1_11685,622,840 - 85,632,064 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001243158   ⟹   NP_001230087
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381684,177,855 - 84,187,057 (-)NCBI
GRCh371684,211,453 - 84,220,676 (-)NCBI
HuRef1669,965,230 - 69,974,453 (-)NCBI
CHM1_11685,622,840 - 85,632,064 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001243159   ⟹   NP_001230088
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381684,177,855 - 84,187,057 (-)NCBI
GRCh371684,211,453 - 84,220,676 (-)NCBI
HuRef1669,965,230 - 69,974,453 (-)NCBI
CHM1_11685,622,840 - 85,632,064 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001243160   ⟹   NP_001230089
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381684,177,855 - 84,187,057 (-)NCBI
GRCh371684,211,453 - 84,220,676 (-)NCBI
HuRef1669,965,230 - 69,974,453 (-)NCBI
CHM1_11685,622,840 - 85,632,064 (-)NCBI
Sequence:
RefSeq Acc Id: NM_005679   ⟹   NP_005670
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381684,177,855 - 84,187,057 (-)NCBI
GRCh371684,211,453 - 84,220,676 (-)NCBI
Build 361682,768,962 - 82,778,163 (-)NCBI Archive
HuRef1669,965,230 - 69,974,453 (-)NCBI
CHM1_11685,622,840 - 85,632,064 (-)NCBI
Sequence:
RefSeq Acc Id: NM_139353   ⟹   NP_647610
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381684,177,855 - 84,187,057 (-)NCBI
GRCh371684,211,453 - 84,220,676 (-)NCBI
Build 361682,768,962 - 82,778,163 (-)NCBI Archive
HuRef1669,965,230 - 69,974,453 (-)NCBI
CHM1_11685,622,840 - 85,632,064 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005256226   ⟹   XP_005256283
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381684,177,852 - 84,187,064 (-)NCBI
Sequence:
RefSeq Acc Id: XM_005256227   ⟹   XP_005256284
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381684,177,852 - 84,187,065 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006721325   ⟹   XP_006721388
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381684,177,852 - 84,187,052 (-)NCBI
Sequence:
RefSeq Acc Id: XM_006721326   ⟹   XP_006721389
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381684,177,852 - 84,187,052 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017023845   ⟹   XP_016879334
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381684,177,852 - 84,187,064 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017023846   ⟹   XP_016879335
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381684,177,852 - 84,187,064 (-)NCBI
Sequence:
RefSeq Acc Id: XM_017023847   ⟹   XP_016879336
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381684,177,852 - 84,187,065 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001230085 (Get FASTA)   NCBI Sequence Viewer  
  NP_001230086 (Get FASTA)   NCBI Sequence Viewer  
  NP_001230087 (Get FASTA)   NCBI Sequence Viewer  
  NP_001230088 (Get FASTA)   NCBI Sequence Viewer  
  NP_001230089 (Get FASTA)   NCBI Sequence Viewer  
  NP_005670 (Get FASTA)   NCBI Sequence Viewer  
  NP_647610 (Get FASTA)   NCBI Sequence Viewer  
  XP_005256283 (Get FASTA)   NCBI Sequence Viewer  
  XP_005256284 (Get FASTA)   NCBI Sequence Viewer  
  XP_006721388 (Get FASTA)   NCBI Sequence Viewer  
  XP_006721389 (Get FASTA)   NCBI Sequence Viewer  
  XP_016879334 (Get FASTA)   NCBI Sequence Viewer  
  XP_016879335 (Get FASTA)   NCBI Sequence Viewer  
  XP_016879336 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA62861 (Get FASTA)   NCBI Sequence Viewer  
  AAH28131 (Get FASTA)   NCBI Sequence Viewer  
  AAN38818 (Get FASTA)   NCBI Sequence Viewer  
  BAD92831 (Get FASTA)   NCBI Sequence Viewer  
  BAG53410 (Get FASTA)   NCBI Sequence Viewer  
  BAH12941 (Get FASTA)   NCBI Sequence Viewer  
  BAH13010 (Get FASTA)   NCBI Sequence Viewer  
  BAH14144 (Get FASTA)   NCBI Sequence Viewer  
  BAH14248 (Get FASTA)   NCBI Sequence Viewer  
  BAH14353 (Get FASTA)   NCBI Sequence Viewer  
  CBX47548 (Get FASTA)   NCBI Sequence Viewer  
  CBX47549 (Get FASTA)   NCBI Sequence Viewer  
  EAW95495 (Get FASTA)   NCBI Sequence Viewer  
  EAW95496 (Get FASTA)   NCBI Sequence Viewer  
  EAW95497 (Get FASTA)   NCBI Sequence Viewer  
  EAW95498 (Get FASTA)   NCBI Sequence Viewer  
  EAW95499 (Get FASTA)   NCBI Sequence Viewer  
  Q15572 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_647610   ⟸   NM_139353
- Peptide Label: isoform 2
- Sequence:
RefSeq Acc Id: NP_005670   ⟸   NM_005679
- Peptide Label: isoform 1
- Sequence:
RefSeq Acc Id: NP_001230089   ⟸   NM_001243160
- Peptide Label: isoform 6
- UniProtKB: B3KUE8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001230086   ⟸   NM_001243157
- Peptide Label: isoform 4
- UniProtKB: Q15572 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001230087   ⟸   NM_001243158
- Peptide Label: isoform 4
- UniProtKB: Q15572 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001230088   ⟸   NM_001243159
- Peptide Label: isoform 5
- UniProtKB: Q15572 (UniProtKB/Swiss-Prot),   B3KUE8 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001230085   ⟸   NM_001243156
- Peptide Label: isoform 3
- Sequence:
RefSeq Acc Id: XP_005256284   ⟸   XM_005256227
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_005256283   ⟸   XM_005256226
- Peptide Label: isoform X2
- UniProtKB: Q15572 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_006721389   ⟸   XM_006721326
- Peptide Label: isoform X3
- Sequence:
RefSeq Acc Id: XP_006721388   ⟸   XM_006721325
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: XP_016879336   ⟸   XM_017023847
- Peptide Label: isoform X6
- Sequence:
RefSeq Acc Id: XP_016879335   ⟸   XM_017023846
- Peptide Label: isoform X5
- Sequence:
RefSeq Acc Id: XP_016879334   ⟸   XM_017023845
- Peptide Label: isoform X4
- UniProtKB: Q15572 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000437900   ⟸   ENST00000541676
RefSeq Acc Id: ENSP00000454494   ⟸   ENST00000569609
RefSeq Acc Id: ENSP00000457281   ⟸   ENST00000569505
RefSeq Acc Id: ENSP00000455247   ⟸   ENST00000570117
RefSeq Acc Id: ENSP00000456011   ⟸   ENST00000561955
RefSeq Acc Id: ENSP00000455787   ⟸   ENST00000563428
RefSeq Acc Id: ENSP00000457883   ⟸   ENST00000564454
RefSeq Acc Id: ENSP00000454854   ⟸   ENST00000564345
RefSeq Acc Id: ENSP00000456133   ⟸   ENST00000566903
RefSeq Acc Id: ENSP00000455933   ⟸   ENST00000566732
RefSeq Acc Id: ENSP00000345305   ⟸   ENST00000341690
RefSeq Acc Id: ENSP00000455265   ⟸   ENST00000567759
RefSeq Acc Id: ENSP00000456101   ⟸   ENST00000568265

Promoters
RGD ID:6793491
Promoter ID:HG_KWN:24369
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   HeLa_S3,   Jurkat,   K562,   Lymphoblastoid,   NB4
Transcripts:ENST00000341690,   NM_005679,   NM_139353,   UC002FHO.1,   UC002FHP.1
Position:
Human AssemblyChrPosition (strand)Source
Build 361682,777,876 - 82,778,376 (-)MPROMDB
RGD ID:7233007
Promoter ID:EPDNEW_H22249
Type:initiation region
Name:TAF1C_1
Description:TATA-box binding protein associated factor, RNA polymerase Isubunit C
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381684,187,037 - 84,187,097EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 16q23.1-24.3(chr16:78816291-90081985)x3 copy number gain See cases [RCV000050840] Chr16:78816291..90081985 [GRCh38]
Chr16:78850188..90148393 [GRCh37]
Chr16:77407689..88675894 [NCBI36]
Chr16:16q23.1-24.3
pathogenic
GRCh38/hg38 16q23.3-24.2(chr16:83878992-87223838)x1 copy number loss See cases [RCV000051122] Chr16:83878992..87223838 [GRCh38]
Chr16:83912597..87257444 [GRCh37]
Chr16:82470098..85814945 [NCBI36]
Chr16:16q23.3-24.2
pathogenic
GRCh38/hg38 16q22.1-24.3(chr16:70514631-90081985)x3 copy number gain See cases [RCV000052422] Chr16:70514631..90081985 [GRCh38]
Chr16:70548534..90148393 [GRCh37]
Chr16:69106035..88675894 [NCBI36]
Chr16:16q22.1-24.3
pathogenic
GRCh38/hg38 16q21-24.3(chr16:65313395-90081985)x3 copy number gain See cases [RCV000052421] Chr16:65313395..90081985 [GRCh38]
Chr16:65347298..90148393 [GRCh37]
Chr16:63904799..88675894 [NCBI36]
Chr16:16q21-24.3
pathogenic
GRCh38/hg38 16q23.3-24.1(chr16:84081930-85474903)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052019]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052019]|See cases [RCV000052019] Chr16:84081930..85474903 [GRCh38]
Chr16:84115535..85508509 [GRCh37]
Chr16:82673036..84066010 [NCBI36]
Chr16:16q23.3-24.1
uncertain significance
GRCh38/hg38 16q23.1-24.3(chr16:76873569-90081985)x3 copy number gain See cases [RCV000052423] Chr16:76873569..90081985 [GRCh38]
Chr16:76907466..90148393 [GRCh37]
Chr16:75464967..88675894 [NCBI36]
Chr16:16q23.1-24.3
pathogenic
GRCh38/hg38 16q23.3-24.3(chr16:82173150-90081985)x3 copy number gain See cases [RCV000052424] Chr16:82173150..90081985 [GRCh38]
Chr16:82206755..90148393 [GRCh37]
Chr16:80764256..88675894 [NCBI36]
Chr16:16q23.3-24.3
pathogenic
GRCh38/hg38 16q23.1-24.2(chr16:78704275-87819342)x1 copy number loss See cases [RCV000053359] Chr16:78704275..87819342 [GRCh38]
Chr16:78738172..87852948 [GRCh37]
Chr16:77295673..86410449 [NCBI36]
Chr16:16q23.1-24.2
pathogenic
GRCh38/hg38 16q23.3-24.1(chr16:81753762-85714791)x1 copy number loss See cases [RCV000053360] Chr16:81753762..85714791 [GRCh38]
Chr16:81787367..85748397 [GRCh37]
Chr16:80344868..84305898 [NCBI36]
Chr16:16q23.3-24.1
pathogenic
GRCh38/hg38 16q23.3-24.1(chr16:83016872-85087809)x1 copy number loss See cases [RCV000053361] Chr16:83016872..85087809 [GRCh38]
Chr16:83050477..85121415 [GRCh37]
Chr16:81607978..83678916 [NCBI36]
Chr16:16q23.3-24.1
pathogenic
GRCh38/hg38 16q22.1-24.1(chr16:70414573-84908120)x1 copy number loss See cases [RCV000133814] Chr16:70414573..84908120 [GRCh38]
Chr16:70448476..84941726 [GRCh37]
Chr16:69005977..83499227 [NCBI36]
Chr16:16q22.1-24.1
pathogenic
GRCh38/hg38 16q23.3-24.1(chr16:83399060-84908120)x1 copy number loss See cases [RCV000133929] Chr16:83399060..84908120 [GRCh38]
Chr16:83432665..84941726 [GRCh37]
Chr16:81990166..83499227 [NCBI36]
Chr16:16q23.3-24.1
pathogenic
GRCh38/hg38 16q23.3-24.3(chr16:83988570-90081985)x3 copy number gain See cases [RCV000135659] Chr16:83988570..90081985 [GRCh38]
Chr16:84022175..90148393 [GRCh37]
Chr16:82579676..88675894 [NCBI36]
Chr16:16q23.3-24.3
likely pathogenic
GRCh38/hg38 16q21-24.1(chr16:62925929-84585795)x3 copy number gain See cases [RCV000135863] Chr16:62925929..84585795 [GRCh38]
Chr16:62959833..84619401 [GRCh37]
Chr16:61517334..83176902 [NCBI36]
Chr16:16q21-24.1
pathogenic
GRCh38/hg38 16q23.3-24.1(chr16:83878992-84908120)x3 copy number gain See cases [RCV000135758] Chr16:83878992..84908120 [GRCh38]
Chr16:83912597..84941726 [GRCh37]
Chr16:82470098..83499227 [NCBI36]
Chr16:16q23.3-24.1
pathogenic|uncertain significance
GRCh38/hg38 16q23.3-24.1(chr16:84063406-84404889)x3 copy number gain See cases [RCV000136480] Chr16:84063406..84404889 [GRCh38]
Chr16:84097011..84438495 [GRCh37]
Chr16:82654512..82995996 [NCBI36]
Chr16:16q23.3-24.1
benign
GRCh38/hg38 16q23.3-24.1(chr16:83687650-86073240)x1 copy number loss See cases [RCV000136504] Chr16:83687650..86073240 [GRCh38]
Chr16:83721255..86106846 [GRCh37]
Chr16:82278756..84664347 [NCBI36]
Chr16:16q23.3-24.1
pathogenic
GRCh38/hg38 16q23.2-24.3(chr16:80946659-90081985)x3 copy number gain See cases [RCV000136898] Chr16:80946659..90081985 [GRCh38]
Chr16:80980556..90148393 [GRCh37]
Chr16:79538057..88675894 [NCBI36]
Chr16:16q23.2-24.3
pathogenic|likely pathogenic
GRCh38/hg38 16q22.1-24.3(chr16:70749398-90096995)x3 copy number gain See cases [RCV000137495] Chr16:70749398..90096995 [GRCh38]
Chr16:70783301..90163403 [GRCh37]
Chr16:69340802..88690904 [NCBI36]
Chr16:16q22.1-24.3
pathogenic
GRCh38/hg38 16q23.3-24.3(chr16:83478453-89932910)x3 copy number gain See cases [RCV000137980] Chr16:83478453..89932910 [GRCh38]
Chr16:83512058..89999318 [GRCh37]
Chr16:82069559..88526819 [NCBI36]
Chr16:16q23.3-24.3
likely pathogenic
GRCh38/hg38 16q21-24.3(chr16:65511483-90096995)x3 copy number gain See cases [RCV000139426] Chr16:65511483..90096995 [GRCh38]
Chr16:65545386..90163403 [GRCh37]
Chr16:64102887..88690904 [NCBI36]
Chr16:16q21-24.3
pathogenic
GRCh38/hg38 16q23.3-24.1(chr16:83763804-84558035)x1 copy number loss See cases [RCV000139413] Chr16:83763804..84558035 [GRCh38]
Chr16:83797409..84591641 [GRCh37]
Chr16:82354910..83149142 [NCBI36]
Chr16:16q23.3-24.1
likely pathogenic|uncertain significance
GRCh38/hg38 16q23.1-24.3(chr16:75377981-90081992)x3 copy number gain See cases [RCV000139302] Chr16:75377981..90081992 [GRCh38]
Chr16:75411879..90148400 [GRCh37]
Chr16:73969380..88675901 [NCBI36]
Chr16:16q23.1-24.3
pathogenic
GRCh38/hg38 16q23.2-24.3(chr16:80717291-90096662)x3 copy number gain See cases [RCV000141128] Chr16:80717291..90096662 [GRCh38]
Chr16:80751188..90163070 [GRCh37]
Chr16:79308689..88690571 [NCBI36]
Chr16:16q23.2-24.3
pathogenic
GRCh38/hg38 16q23.3-24.1(chr16:83763804-84276472)x3 copy number gain See cases [RCV000140831] Chr16:83763804..84276472 [GRCh38]
Chr16:83797409..84310078 [GRCh37]
Chr16:82354910..82867579 [NCBI36]
Chr16:16q23.3-24.1
uncertain significance
GRCh38/hg38 16q23.1-24.3(chr16:76336203-90088654)x3 copy number gain See cases [RCV000141700] Chr16:76336203..90088654 [GRCh38]
Chr16:76370100..90155062 [GRCh37]
Chr16:74927601..88682563 [NCBI36]
Chr16:16q23.1-24.3
pathogenic
GRCh38/hg38 16q21-24.3(chr16:64389378-90081985)x3 copy number gain See cases [RCV000142578] Chr16:64389378..90081985 [GRCh38]
Chr16:64423281..90148393 [GRCh37]
Chr16:62980782..88675894 [NCBI36]
Chr16:16q21-24.3
pathogenic|likely pathogenic
GRCh38/hg38 16q23.2-24.3(chr16:80067315-90057871)x3 copy number gain See cases [RCV000142698] Chr16:80067315..90057871 [GRCh38]
Chr16:80101212..90124279 [GRCh37]
Chr16:78658713..88651780 [NCBI36]
Chr16:16q23.2-24.3
pathogenic
GRCh38/hg38 16q12.2-24.3(chr16:52899183-90088654)x3 copy number gain See cases [RCV000143425] Chr16:52899183..90088654 [GRCh38]
Chr16:52933095..90155062 [GRCh37]
Chr16:51490596..88682563 [NCBI36]
Chr16:16q12.2-24.3
pathogenic
NM_178452.4(DNAAF1):c.(?_-181)_(*77_?)del deletion Primary ciliary dyskinesia [RCV000150412] Chr16:84178865..84211524 [GRCh37]
Chr16:16q23.3-24.1
pathogenic
GRCh37/hg19 16q23.1-24.3(chr16:74872514-90274440)x3 copy number gain See cases [RCV000240108] Chr16:74872514..90274440 [GRCh37]
Chr16:16q23.1-24.3
pathogenic
t(5;16)(p15.31;q23.1) translocation not provided [RCV000203391] Chr5:1..8180513 [GRCh37]
Chr16:76935310..90354753 [GRCh37]
Chr5:5p15.33-15.31
Chr16:16q23.1-24.3
likely pathogenic
GRCh37/hg19 16q23.3-24.1(chr16:83553094-86098013)x1 copy number loss See cases [RCV000203439] Chr16:83553094..86098013 [GRCh37]
Chr16:16q23.3-24.1
likely pathogenic
GRCh37/hg19 16q11.2-24.3(chr16:46615804-90142285)x1 copy number loss Ductal breast carcinoma [RCV000207138] Chr16:46615804..90142285 [GRCh37]
Chr16:16q11.2-24.3
uncertain significance
GRCh37/hg19 16q22.2-24.3(chr16:72107834-90142285)x1 copy number loss Ductal breast carcinoma [RCV000207182] Chr16:72107834..90142285 [GRCh37]
Chr16:16q22.2-24.3
uncertain significance
Single allele complex Ductal breast carcinoma [RCV000207314] Chr16:56368689..90141355 [GRCh37]
Chr16:16q12.2-24.3
uncertain significance
GRCh37/hg19 16q23.3-24.1(chr16:83496909-84695933)x1 copy number loss See cases [RCV000240561] Chr16:83496909..84695933 [GRCh37]
Chr16:16q23.3-24.1
uncertain significance
NM_178452.6(DNAAF1):c.*36C>T single nucleotide variant Ciliary dyskinesia, primary, 13 [RCV000392225]|not specified [RCV000244644] Chr16:84177877 [GRCh38]
Chr16:84211483 [GRCh37]
Chr16:16q24.1
benign
NM_178452.6(DNAAF1):c.*18T>C single nucleotide variant Ciliary dyskinesia, primary, 13 [RCV000343172]|not specified [RCV000252615] Chr16:84177859 [GRCh38]
Chr16:84211465 [GRCh37]
Chr16:16q24.1
benign|uncertain significance
NM_178452.6(DNAAF1):c.*16T>C single nucleotide variant Ciliary dyskinesia, primary, 13 [RCV000278690] Chr16:84177857 [GRCh38]
Chr16:84211463 [GRCh37]
Chr16:16q24.1
uncertain significance
NM_178452.6(DNAAF1):c.*67T>C single nucleotide variant Ciliary dyskinesia, primary, 13 [RCV000339757] Chr16:84177908 [GRCh38]
Chr16:84211514 [GRCh37]
Chr16:16q24.1
likely benign|uncertain significance
NM_178452.6(DNAAF1):c.*43_*46del deletion Primary ciliary dyskinesia [RCV000284723] Chr16:84177883..84177886 [GRCh38]
Chr16:84211489..84211492 [GRCh37]
Chr16:16q24.1
uncertain significance
GRCh37/hg19 16q11.2-24.3(chr16:46464488-90155062)x3 copy number gain See cases [RCV000446110] Chr16:46464488..90155062 [GRCh37]
Chr16:16q11.2-24.3
pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:69193-90274381)x3 copy number gain See cases [RCV000446684] Chr16:69193..90274381 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
GRCh37/hg19 16q23.3-24.1(chr16:84115509-84214129)x1 copy number loss See cases [RCV000448516] Chr16:84115509..84214129 [GRCh37]
Chr16:16q23.3-24.1
uncertain significance
GRCh37/hg19 16q23.3-24.1(chr16:84098379-84402295)x3 copy number gain See cases [RCV000448558] Chr16:84098379..84402295 [GRCh37]
Chr16:16q23.3-24.1
uncertain significance
NM_001243156.2(TAF1C):c.1645T>A (p.Leu549Met) single nucleotide variant not specified [RCV000455673] Chr16:84179828 [GRCh38]
Chr16:84213434 [GRCh37]
Chr16:16q24.1
benign
GRCh37/hg19 16q23.3-24.1(chr16:83926471-84215425)x1 copy number loss See cases [RCV000510184] Chr16:83926471..84215425 [GRCh37]
Chr16:16q23.3-24.1
uncertain significance
GRCh37/hg19 16p13.2-q24.3(chr16:9273328-89548493)x3 copy number gain See cases [RCV000511622] Chr16:9273328..89548493 [GRCh37]
Chr16:16p13.2-q24.3
uncertain significance
GRCh37/hg19 16q11.2-24.3(chr16:46455960-90354753)x1 copy number loss PARP Inhibitor response [RCV000626435] Chr16:46455960..90354753 [GRCh37]
Chr16:16q11.2-24.3
drug response
GRCh37/hg19 16p13.3-q24.3(chr16:85881-90155062) copy number gain See cases [RCV000511296] Chr16:85881..90155062 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:85881-90155062)x3 copy number gain See cases [RCV000512138] Chr16:85881..90155062 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
GRCh37/hg19 16q13-24.3(chr16:57051473-89797669)x3 copy number gain See cases [RCV000512511] Chr16:57051473..89797669 [GRCh37]
Chr16:16q13-24.3
pathogenic
GRCh37/hg19 16q23.3-24.3(chr16:83001540-90155062)x3 copy number gain See cases [RCV000512468] Chr16:83001540..90155062 [GRCh37]
Chr16:16q23.3-24.3
likely pathogenic
GRCh37/hg19 16q11.2-24.3(chr16:46497599-90354753)x1 copy number loss PARP Inhibitor response [RCV000626429] Chr16:46497599..90354753 [GRCh37]
Chr16:16q11.2-24.3
drug response
GRCh37/hg19 16q23.3-24.1(chr16:84111320-84485022)x3 copy number gain not provided [RCV000683852] Chr16:84111320..84485022 [GRCh37]
Chr16:16q23.3-24.1
uncertain significance
GRCh37/hg19 16q23.2-24.3(chr16:79400436-90155062)x3 copy number gain not provided [RCV000683845] Chr16:79400436..90155062 [GRCh37]
Chr16:16q23.2-24.3
pathogenic
GRCh37/hg19 16q22.2-24.3(chr16:72515938-90155062)x3 copy number gain not provided [RCV000683831] Chr16:72515938..90155062 [GRCh37]
Chr16:16q22.2-24.3
pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:88165-90274695)x3 copy number gain not provided [RCV000738918] Chr16:88165..90274695 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:61451-90294632)x3 copy number gain not provided [RCV000738915] Chr16:61451..90294632 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
GRCh37/hg19 16p13.3-q24.3(chr16:88165-90163275)x3 copy number gain not provided [RCV000738917] Chr16:88165..90163275 [GRCh37]
Chr16:16p13.3-q24.3
pathogenic
GRCh37/hg19 16q23.3-24.1(chr16:83813294-84984350)x3 copy number gain not provided [RCV000739258] Chr16:83813294..84984350 [GRCh37]
Chr16:16q23.3-24.1
likely benign
GRCh37/hg19 16q23.3-24.1(chr16:84145386-84724295)x3 copy number gain not provided [RCV000751788] Chr16:84145386..84724295 [GRCh37]
Chr16:16q23.3-24.1
uncertain significance
GRCh37/hg19 16q23.3-24.3(chr16:82761333-90055381) copy number gain not provided [RCV000767619] Chr16:82761333..90055381 [GRCh37]
Chr16:16q23.3-24.3
pathogenic
GRCh37/hg19 16q23.3-24.1(chr16:83330709-84866927)x1 copy number loss not provided [RCV001006830] Chr16:83330709..84866927 [GRCh37]
Chr16:16q23.3-24.1
uncertain significance
NM_001243156.2(TAF1C):c.534G>A (p.Gly178=) single nucleotide variant not provided [RCV000891588] Chr16:84182389 [GRCh38]
Chr16:84215995 [GRCh37]
Chr16:16q24.1
benign
GRCh37/hg19 16q23.2-24.1(chr16:79254648-84827672)x1 copy number loss not provided [RCV000849998] Chr16:79254648..84827672 [GRCh37]
Chr16:16q23.2-24.1
uncertain significance
GRCh37/hg19 16q21-24.3(chr16:61524229-90155062)x3 copy number gain not provided [RCV001249359] Chr16:61524229..90155062 [GRCh37]
Chr16:16q21-24.3
not provided
NM_001243156.2(TAF1C):c.1704C>G (p.Val568=) single nucleotide variant not provided [RCV000971416] Chr16:84179769 [GRCh38]
Chr16:84213375 [GRCh37]
Chr16:16q24.1
benign
Single allele deletion Persistent fetal circulation syndrome [RCV001251455] Chr16:83931797..86285776 [GRCh37]
Chr16:16q23.3-24.1
likely pathogenic
GRCh37/hg19 16q23.3-24.1(chr16:83866931-85276940)x3 copy number gain not provided [RCV001258657] Chr16:83866931..85276940 [GRCh37]
Chr16:16q23.3-24.1
uncertain significance

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:11534 AgrOrtholog
COSMIC TAF1C COSMIC
Ensembl Genes ENSG00000103168 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000345305 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000437900 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000454494 UniProtKB/TrEMBL
  ENSP00000454854 UniProtKB/TrEMBL
  ENSP00000455247 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000455265 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000455787 UniProtKB/TrEMBL
  ENSP00000455933 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000456011 UniProtKB/TrEMBL
  ENSP00000456101 UniProtKB/TrEMBL
  ENSP00000456133 UniProtKB/TrEMBL
  ENSP00000457281 UniProtKB/TrEMBL
  ENSP00000457883 UniProtKB/TrEMBL
Ensembl Transcript ENST00000341690 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000541676 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000561955 UniProtKB/TrEMBL
  ENST00000563428 UniProtKB/TrEMBL
  ENST00000564208 ENTREZGENE
  ENST00000564345 UniProtKB/TrEMBL
  ENST00000564454 UniProtKB/TrEMBL
  ENST00000566732 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000566903 UniProtKB/TrEMBL
  ENST00000567759 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000568265 UniProtKB/TrEMBL
  ENST00000569505 UniProtKB/TrEMBL
  ENST00000569609 UniProtKB/TrEMBL
  ENST00000570117 ENTREZGENE, UniProtKB/Swiss-Prot
Gene3D-CATH 2.130.10.10 UniProtKB/Swiss-Prot
GTEx ENSG00000103168 GTEx
HGNC ID HGNC:11534 ENTREZGENE
Human Proteome Map TAF1C Human Proteome Map
InterPro TAF1C UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  WD40/YVTN_repeat-like_dom_sf UniProtKB/Swiss-Prot
  WD40_repeat_dom_sf UniProtKB/Swiss-Prot
KEGG Report hsa:9013 UniProtKB/Swiss-Prot
NCBI Gene 9013 ENTREZGENE
OMIM 604905 OMIM
PANTHER PTHR15319 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA36309 PharmGKB
Superfamily-SCOP SSF50978 UniProtKB/Swiss-Prot
UniGene Hs.153022 ENTREZGENE
UniProt B3KUE8 ENTREZGENE, UniProtKB/TrEMBL
  H3BMQ4_HUMAN UniProtKB/TrEMBL
  H3BNH3_HUMAN UniProtKB/TrEMBL
  H3BQH8_HUMAN UniProtKB/TrEMBL
  H3BQZ8_HUMAN UniProtKB/TrEMBL
  H3BR71_HUMAN UniProtKB/TrEMBL
  H3BR91_HUMAN UniProtKB/TrEMBL
  H3BTQ6_HUMAN UniProtKB/TrEMBL
  H3BUZ7_HUMAN UniProtKB/TrEMBL
  Q15572 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B7Z5K5 UniProtKB/Swiss-Prot
  B7Z5S4 UniProtKB/Swiss-Prot
  B7Z908 UniProtKB/Swiss-Prot
  B7Z9L7 UniProtKB/Swiss-Prot
  Q59F67 UniProtKB/Swiss-Prot
  Q8N6V3 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-07 TAF1C  TATA-box binding protein associated factor, RNA polymerase I subunit C    TATA-box binding protein associated factor, RNA polymerase I, C  Symbol and/or name change 5135510 APPROVED
2015-11-24 TAF1C  TATA-box binding protein associated factor, RNA polymerase I, C    TATA box binding protein (TBP)-associated factor, RNA polymerase I, C, 110kDa  Symbol and/or name change 5135510 APPROVED