(RS)-amphetamine decreases expression ISO RGD:1562602 6480464 Amphetamine results in decreased expression of PML mRNA CTD PMID:30779732 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO RGD:1557220 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO RGD:1557220 6480464 Tetrachlorodibenzodioxin results in increased expression of PML mRNA CTD PMID:19933214 , PMID:21889950 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO RGD:1557220 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:25975270 , PMID:28433925 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO RGD:1557220 6480464 Tetrachlorodibenzodioxin affects the expression of PML mRNA CTD PMID:21570461 3,3',5,5'-tetrabromobisphenol A increases expression ISO RGD:1562602 6480464 tetrabromobisphenol A results in increased expression of PML mRNA CTD PMID:27914987 3-methyladenine multiple interactions EXP 6480464 3-methyladenine inhibits the reaction [4-amino-2-trifluoromethyl-phenyl retinate results in increased degradation of [PML protein mutant form binds to RARA protein mutant form]] CTD PMID:28130038 4'-epidoxorubicin affects mutagenesis EXP 6480464 Epirubicin affects the mutagenesis of PML gene CTD PMID:19884644 4,4'-diaminodiphenylmethane increases expression ISO RGD:1557220 6480464 4, 4'-diaminodiphenylmethane results in increased expression of PML mRNA CTD PMID:18648102 5-azacytidine increases expression EXP 6480464 Azacitidine results in increased expression of PML mRNA CTD PMID:19194470 6-propyl-2-thiouracil affects expression ISO RGD:1562602 6480464 Propylthiouracil affects the expression of PML mRNA CTD PMID:24780913 7,9-dihydro-1H-purine-2,6,8(3H)-trione multiple interactions ISO RGD:1557220 6480464 PML protein promotes the reaction [[Lipopolysaccharides co-treated with Uric Acid] results in increased expression of IL1B protein] more ... CTD PMID:23430110 aflatoxin B1 increases expression ISO RGD:1557220 6480464 Aflatoxin B1 results in increased expression of PML mRNA CTD PMID:19770486 aflatoxin B1 increases expression EXP 6480464 Aflatoxin B1 results in increased expression of PML mRNA CTD PMID:21641981 all-trans-retinoic acid affects localization EXP 6480464 Tretinoin affects the localization of PML protein CTD PMID:9834237 all-trans-retinoic acid increases degradation EXP 6480464 Tretinoin results in increased degradation of PML protein mutant form CTD PMID:15748426 more ... all-trans-retinoic acid increases phosphorylation EXP 6480464 Tretinoin results in increased phosphorylation of PML protein mutant form CTD PMID:19029980 all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of PML mRNA CTD PMID:16249480 all-trans-retinoic acid increases cleavage EXP 6480464 Tretinoin results in increased cleavage of PML protein mutant form CTD PMID:12130515 all-trans-retinoic acid increases expression EXP 6480464 Tretinoin results in increased expression of PML protein CTD PMID:12015078 all-trans-retinoic acid multiple interactions EXP 6480464 [Tretinoin co-treated with arsenic trioxide] results in decreased expression of PML mRNA alternative form more ... CTD PMID:12130515 more ... aluminium sulfate (anhydrous) multiple interactions ISO RGD:1557220 6480464 [Lipopolysaccharides co-treated with aluminum sulfate] results in increased expression of PML protein CTD PMID:23430110 Antimony trioxide affects localization EXP 6480464 antimony trioxide affects the localization of PML protein CTD PMID:9834237 Antimony trioxide increases degradation EXP 6480464 antimony trioxide results in increased degradation of PML protein mutant form CTD PMID:9834237 Antimony trioxide multiple interactions EXP 6480464 antimony trioxide promotes the reaction [SUMO1 protein binds to PML protein] CTD PMID:9834237 antimony(0) multiple interactions EXP 6480464 Antimony affects the localization of and results in increased sumoylation of PML protein CTD PMID:26049103 antimony(3+) multiple interactions EXP 6480464 Antimony affects the localization of and results in increased sumoylation of PML protein CTD PMID:26049103 Aroclor 1254 decreases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in decreased expression of PML mRNA CTD PMID:16934159 arsane increases degradation EXP 6480464 Arsenic results in increased degradation of PML protein CTD PMID:18408734 arsane multiple interactions EXP 6480464 RNF4 protein promotes the reaction [Arsenic results in increased degradation of PML protein] CTD PMID:18408734 arsenic atom multiple interactions EXP 6480464 RNF4 protein promotes the reaction [Arsenic results in increased degradation of PML protein] CTD PMID:18408734 arsenic atom increases degradation EXP 6480464 Arsenic results in increased degradation of PML protein CTD PMID:18408734 arsenic(3+) increases degradation EXP 6480464 Arsenic results in increased degradation of PML protein CTD PMID:18408734 arsenic(3+) multiple interactions EXP 6480464 RNF4 protein promotes the reaction [Arsenic results in increased degradation of PML protein] CTD PMID:18408734 arsenite(3-) increases response to substance EXP 6480464 PML protein results in increased susceptibility to arsenite CTD PMID:24135626 arsenite(3-) increases sumoylation EXP 6480464 arsenite results in increased sumoylation of PML protein CTD PMID:24135626 ATP multiple interactions ISO RGD:1557220 6480464 [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PML protein] more ... CTD PMID:23430110 benzo[a]pyrene increases mutagenesis EXP 6480464 Benzo(a)pyrene results in increased mutagenesis of PML gene CTD PMID:25435355 benzo[a]pyrene decreases expression ISO RGD:1557220 6480464 Benzo(a)pyrene results in decreased expression of PML mRNA CTD PMID:22228805 benzo[a]pyrene increases expression ISO RGD:1557220 6480464 Benzo(a)pyrene results in increased expression of PML mRNA CTD PMID:19770486 more ... bis(2-ethylhexyl) phthalate multiple interactions ISO RGD:1557220 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 bisphenol A affects expression ISO RGD:1562602 6480464 bisphenol A affects the expression of PML mRNA CTD PMID:25181051 bisphenol A multiple interactions ISO RGD:1557220 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 bleomycin A2 increases expression ISO RGD:1557220 6480464 Bleomycin results in increased expression of PML protein CTD PMID:24762191 bleomycin A2 multiple interactions ISO RGD:1557220 6480464 arsenic trioxide inhibits the reaction [Bleomycin results in increased expression of PML protein] CTD PMID:24762191 buta-1,3-diene decreases expression ISO RGD:1557220 6480464 1, 3-butadiene results in decreased expression of PML mRNA CTD PMID:29038090 cadmium dichloride multiple interactions ISO RGD:1557220 6480464 PML gene mutant form inhibits the reaction [Cadmium Chloride results in increased expression of CCND1 protein], PML protein affects the reaction [Cadmium Chloride affects the localization of CCND1 mRNA] CTD PMID:12167712 cadmium dichloride affects localization ISO RGD:1557220 6480464 Cadmium Chloride affects the localization of PML protein CTD PMID:12167712 calciol multiple interactions EXP 6480464 PML protein mutant form inhibits the reaction [[Cholecalciferol co-treated with TGFB1 protein] results in increased expression of CD14 mRNA] CTD PMID:15988048 carbon nanotube increases expression ISO RGD:1557220 6480464 Nanotubes, Carbon analog results in increased expression of PML mRNA, Nanotubes, Carbon results in increased expression of PML mRNA CTD PMID:25554681 cisplatin increases expression ISO RGD:1557220 6480464 Cisplatin results in increased expression of PML mRNA CTD PMID:21151649 cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of PML mRNA CTD PMID:27392435 cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of PML mRNA CTD PMID:27392435 cobalt dichloride multiple interactions EXP 6480464 cobaltous chloride promotes the reaction [arsenic trioxide results in increased degradation of PML protein mutant form] CTD PMID:16330433 cycloheximide decreases degradation EXP 6480464 Cycloheximide results in decreased degradation of PML protein modified form CTD PMID:26049103 cycloheximide multiple interactions EXP 6480464 Cycloheximide inhibits the reaction [arsenic trioxide results in increased degradation of PML protein] CTD PMID:20943951 DAPT multiple interactions EXP 6480464 N-(N-(3, 5-difluorophenacetyl)alanyl)phenylglycine tert-butyl ester inhibits the reaction [4-amino-2-trifluoromethyl-phenyl retinate results in increased degradation of [PML protein mutant form binds to RARA protein mutant form]] CTD PMID:28130038 deoxynivalenol decreases phosphorylation ISO RGD:1557220 6480464 deoxynivalenol results in decreased phosphorylation of PML protein CTD PMID:23811945 deoxynivalenol affects phosphorylation ISO RGD:1557220 6480464 deoxynivalenol affects the phosphorylation of PML protein CTD PMID:23352502 dicrotophos increases expression EXP 6480464 dicrotophos results in increased expression of PML mRNA CTD PMID:28302478 dimercaprol multiple interactions EXP 6480464 Dimercaprol inhibits the reaction [4-aminophenylarsenoxide binds to PML protein] CTD PMID:26598702 dimethylarsinous acid multiple interactions EXP 6480464 [monomethylarsonous acid co-treated with dimethylarsinous acid co-treated with Arsenic Trioxide] results in increased degradation of PML protein CTD PMID:29774349 dioxygen affects methylation ISO RGD:1557220 6480464 Oxygen deficiency affects the methylation of PML promoter CTD PMID:24205000 dioxygen increases expression ISO RGD:1557220 6480464 Oxygen deficiency results in increased expression of PML mRNA CTD PMID:24205000 dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate increases degradation EXP 6480464 Antimony Potassium Tartrate results in increased degradation of PML protein mutant form CTD PMID:9834237 dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate affects localization EXP 6480464 Antimony Potassium Tartrate affects the localization of PML protein CTD PMID:9834237 dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate multiple interactions EXP 6480464 Antimony Potassium Tartrate promotes the reaction [SUMO1 protein binds to PML protein] CTD PMID:9834237 dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PML mRNA CTD PMID:27188386 doxorubicin decreases expression EXP 6480464 Doxorubicin results in decreased expression of PML mRNA CTD PMID:29803840 elemental selenium multiple interactions EXP 6480464 [Selenium co-treated with Vitamin E] results in increased expression of PML mRNA CTD PMID:19244175 elemental selenium increases expression EXP 6480464 Selenium results in increased expression of PML mRNA CTD PMID:19244175 ellagic acid decreases expression EXP 6480464 Ellagic Acid results in decreased expression of PML mRNA CTD PMID:12002526 endosulfan decreases expression ISO RGD:1562602 6480464 Endosulfan results in decreased expression of PML mRNA CTD PMID:29391264 enzyme inhibitor multiple interactions EXP 6480464 [Enzyme Inhibitors results in decreased activity of OGA protein] which results in increased O-linked glycosylation of PML protein CTD PMID:23301498 erlotinib hydrochloride increases localization EXP 6480464 Erlotinib Hydrochloride results in increased localization of PML protein CTD PMID:23440206 erlotinib hydrochloride decreases response to substance EXP 6480464 PML protein results in decreased susceptibility to Erlotinib Hydrochloride CTD PMID:23440206 erlotinib hydrochloride increases expression EXP 6480464 Erlotinib Hydrochloride results in increased expression of PML protein CTD PMID:23440206 ethyl methanesulfonate increases expression EXP 6480464 Ethyl Methanesulfonate results in increased expression of PML mRNA CTD PMID:23649840 fenamidone increases expression ISO RGD:1557220 6480464 fenamidone results in increased expression of PML mRNA CTD PMID:27029645 fenvalerate affects methylation ISO RGD:1557220 6480464 fenvalerate affects the methylation of PML gene CTD PMID:23548413 fluoranthene multiple interactions ISO RGD:1557220 6480464 [1-methylanthracene co-treated with fluoranthene] results in decreased expression of PML mRNA CTD PMID:28329830 Ginkgoic acid decreases response to substance ISO RGD:1557220 6480464 PML protein results in decreased susceptibility to ginkgolic acid CTD PMID:29524504 Ginkgoic acid multiple interactions ISO RGD:1557220 6480464 ginkgolic acid inhibits the reaction [AGT protein modified form results in increased sumoylation of PML protein] more ... CTD PMID:29524504 hydroxyurea increases expression ISO RGD:1557220 6480464 Hydroxyurea results in increased expression of PML mRNA CTD PMID:27208086 ibuprofen affects expression EXP 6480464 Ibuprofen affects the expression of PML mRNA CTD PMID:17070997 leptomycin B multiple interactions ISO RGD:1557220 6480464 leptomycin B inhibits the reaction [Lipopolysaccharides results in increased localization of PML protein] CTD PMID:23430110 lipopolysaccharide multiple interactions ISO RGD:1557220 6480464 [Lipopolysaccharides co-treated with Adenosine Triphosphate] promotes the reaction [NLRP3 protein binds to PML protein] more ... CTD PMID:23430110 lipopolysaccharide increases expression EXP 6480464 Lipopolysaccharides results in increased expression of PML protein CTD PMID:30501627 lipopolysaccharide increases localization ISO RGD:1557220 6480464 Lipopolysaccharides results in increased localization of PML protein CTD PMID:23430110 lipopolysaccharide increases expression ISO RGD:1557220 6480464 Lipopolysaccharides results in increased expression of PML mRNA, Lipopolysaccharides results in increased expression of PML protein CTD PMID:12057914 , PMID:23430110 methyl methanesulfonate increases expression EXP 6480464 Methyl Methanesulfonate results in increased expression of PML mRNA CTD PMID:23649840 mitoxantrone affects mutagenesis EXP 6480464 Mitoxantrone affects the mutagenesis of PML gene CTD PMID:19884644 N-(6-acetamidohexyl)acetamide multiple interactions EXP 6480464 [Tretinoin co-treated with hexamethylene bisacetamide] results in increased cleavage of PML protein mutant form CTD PMID:12130515 N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal decreases degradation EXP 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in decreased degradation of PML protein modified form CTD PMID:26049103 N-nitrosodiethylamine increases expression ISO RGD:1557220 6480464 Diethylnitrosamine results in increased expression of PML mRNA CTD PMID:17854601 N-nitrosodiethylamine multiple interactions ISO RGD:1557220 6480464 RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of PML mRNA] CTD PMID:17854601 nickel atom increases expression EXP 6480464 Nickel results in increased expression of PML mRNA CTD PMID:24768652 , PMID:25583101 p-menthan-3-ol decreases expression EXP 6480464 Menthol results in decreased expression of PML mRNA CTD PMID:26760959 paraquat multiple interactions ISO RGD:1557220 6480464 Paraquat promotes the reaction [PML protein binds to PML protein], Paraquat results in increased sumoylation of and results in increased localization of and results in increased degradation of [PML protein mutant form binds to PML protein mutant form] CTD PMID:20609355 pentachlorophenol increases expression ISO RGD:1557220 6480464 Pentachlorophenol results in increased expression of PML mRNA CTD PMID:23892564 phenylmercury acetate multiple interactions EXP 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PML mRNA CTD PMID:27188386 pirinixic acid decreases expression ISO RGD:1557220 6480464 pirinixic acid results in decreased expression of PML mRNA CTD PMID:17426115 propiconazole decreases expression ISO RGD:1557220 6480464 propiconazole results in decreased expression of PML mRNA CTD PMID:21278054 puerarin multiple interactions EXP 6480464 arsenic trioxide promotes the reaction [puerarin results in decreased expression of PML mRNA alternative form] CTD PMID:20416161 puerarin decreases expression EXP 6480464 puerarin results in decreased expression of PML mRNA alternative form CTD PMID:20416161 reactive oxygen species multiple interactions ISO RGD:1557220 6480464 PML protein promotes the reaction [[Lipopolysaccharides co-treated with Adenosine Triphosphate] results in increased abundance of Reactive Oxygen Species] CTD PMID:23430110 resiquimod multiple interactions ISO RGD:1557220 6480464 PML protein promotes the reaction [[resiquimod co-treated with Adenosine Triphosphate] results in increased expression of IL1B protein] CTD PMID:23430110 resveratrol multiple interactions EXP 6480464 BCL2 protein inhibits the reaction [resveratrol promotes the reaction [PML protein binds to CREBBP protein]] more ... CTD PMID:19631782 resveratrol increases expression EXP 6480464 resveratrol results in increased expression of PML mRNA CTD PMID:25436977 rofecoxib increases expression EXP 6480464 rofecoxib results in increased expression of PML mRNA CTD PMID:17070997 SB 431542 multiple interactions EXP 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1, 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of PML mRNA CTD PMID:27188386 selenium atom multiple interactions EXP 6480464 [Selenium co-treated with Vitamin E] results in increased expression of PML mRNA CTD PMID:19244175 selenium atom increases expression EXP 6480464 Selenium results in increased expression of PML mRNA CTD PMID:19244175 silicon dioxide decreases expression EXP 6480464 Silicon Dioxide analog results in decreased expression of PML mRNA CTD PMID:25895662 silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of PML mRNA CTD PMID:25351596 silver atom decreases expression ISO RGD:1557220 6480464 Silver results in decreased expression of PML mRNA CTD PMID:27131904 silver(0) decreases expression ISO RGD:1557220 6480464 Silver results in decreased expression of PML mRNA CTD PMID:27131904 silver(1+) decreases expression ISO RGD:1557220 6480464 Silver results in decreased expression of PML mRNA CTD PMID:27131904 sirolimus increases expression EXP 6480464 Sirolimus results in increased expression of PML protein CTD PMID:23440206 sirolimus increases localization EXP 6480464 Sirolimus results in increased localization of PML protein CTD PMID:23440206 sirolimus decreases response to substance EXP 6480464 PML protein results in decreased susceptibility to Sirolimus CTD PMID:23440206 sodium arsenate increases expression ISO RGD:1557220 6480464 sodium arsenate results in increased expression of PML mRNA CTD PMID:21795629 sodium arsenite multiple interactions EXP 6480464 sodium arsenite affects the localization of and results in increased sumoylation of PML protein CTD PMID:26049103 sodium arsenite decreases expression EXP 6480464 sodium arsenite results in decreased expression of PML mRNA CTD PMID:12016162 sulindac increases expression EXP 6480464 Sulindac results in increased expression of PML mRNA CTD PMID:16273229 thimerosal decreases expression EXP 6480464 Thimerosal results in decreased expression of PML mRNA CTD PMID:27188386 troglitazone decreases expression ISO RGD:1557220 6480464 troglitazone results in decreased expression of PML mRNA CTD PMID:28973697 valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of PML mRNA CTD PMID:29154799 valproic acid increases expression EXP 6480464 Valproic Acid results in increased expression of PML mRNA CTD PMID:28001369 valproic acid affects expression ISO RGD:1557220 6480464 Valproic Acid affects the expression of PML mRNA CTD PMID:17963808 vanadyl sulfate decreases expression EXP 6480464 vanadyl sulfate results in decreased expression of PML mRNA CTD PMID:16330358 vitamin E multiple interactions EXP 6480464 [Selenium co-treated with Vitamin E] results in increased expression of PML mRNA CTD PMID:19244175 vitamin E increases expression EXP 6480464 Vitamin E results in increased expression of PML mRNA CTD PMID:19244175 vorinostat multiple interactions EXP 6480464 [vorinostat co-treated with arsenic trioxide] results in decreased expression of PML protein mutant form more ... CTD PMID:19631782 , PMID:27189198 vorinostat decreases expression EXP 6480464 vorinostat results in decreased expression of PML protein mutant form CTD PMID:27189198 zebularine decreases expression EXP 6480464 pyrimidin-2-one beta-ribofuranoside results in decreased expression of PML mRNA CTD PMID:19194470 zinc atom increases expression EXP 6480464 Zinc results in increased expression of PML protein mutant form CTD PMID:16330433 zinc(0) increases expression EXP 6480464 Zinc results in increased expression of PML protein mutant form CTD PMID:16330433
Biological Process activation of cysteine-type endopeptidase activity involved in apoptotic process IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 apoptotic process IDA 2290271 UniProtKB PMID:9583681 branching involved in mammary gland duct morphogenesis IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 cell cycle arrest IDA 2290271 UniProtKB PMID:12773567 , PMID:9583681 cell cycle arrest IBA MGI:MGI:104662 more ... 2290271 GO_Central PMID:21873635 cell fate commitment IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 cellular response to interleukin-4 IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 cellular response to leukemia inhibitory factor IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 cellular senescence IDA 2290271 UniProtKB PMID:22002537 more ... circadian regulation of gene expression ISS UniProtKB:Q60953 2290271 UniProtKB GO_REF:0000024 common-partner SMAD protein phosphorylation IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 defense response to virus IEA UniProtKB-KW:KW-0051 2290271 UniProtKB GO_REF:0000037 DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest ISS UniProtKB:Q60953 2290271 UniProtKB GO_REF:0000024 endoplasmic reticulum calcium ion homeostasis ISS UniProtKB:Q60953 2290271 UniProtKB GO_REF:0000024 entrainment of circadian clock by photoperiod ISS UniProtKB:Q60953 2290271 UniProtKB GO_REF:0000024 extrinsic apoptotic signaling pathway IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 fibroblast migration IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 innate immune response IDA 2290271 UniProtKB PMID:18248090 innate immune response IBA MGI:MGI:104662 more ... 2290271 GO_Central PMID:21873635 interferon-gamma-mediated signaling pathway TAS 2290271 Reactome Reactome:R-HSA-877300 intrinsic apoptotic signaling pathway in response to DNA damage IDA 2290271 UniProtKB PMID:12402044 intrinsic apoptotic signaling pathway in response to DNA damage IBA MGI:MGI:104662 more ... 2290271 GO_Central PMID:21873635 intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator ISS UniProtKB:Q60953 2290271 UniProtKB GO_REF:0000024 intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 intrinsic apoptotic signaling pathway in response to oxidative stress IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 maintenance of protein location in nucleus IDA 2290271 MGI PMID:17332504 myeloid cell differentiation IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 negative regulation of angiogenesis IMP 2290271 UniProtKB PMID:16915281 negative regulation of cell growth IDA 2290271 UniProtKB PMID:7935403 more ... negative regulation of cell population proliferation IMP 2290271 BHF-UCL PMID:12006491 negative regulation of interleukin-1 beta secretion IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 negative regulation of mitotic cell cycle IDA 2290271 UniProtKB PMID:9395203 negative regulation of telomerase activity IMP 2290271 UniProtKB PMID:19567472 negative regulation of telomere maintenance via telomerase IMP 2290271 UniProtKB PMID:19567472 negative regulation of transcription, DNA-templated IDA 2290271 UniProtKB PMID:11259576 more ... negative regulation of translation in response to oxidative stress IDA 2290271 UniProtKB PMID:16915281 negative regulation of ubiquitin-dependent protein catabolic process IMP 2290271 UniProtKB PMID:15195100 negative regulation of viral release from host cell IDA 2290271 UniProtKB PMID:18248090 negative regulation of viral release from host cell IBA MGI:MGI:104662 more ... 2290271 GO_Central PMID:21873635 PML body organization IMP 2290271 UniProtKB PMID:17081985 PML body organization IBA MGI:MGI:104662 more ... 2290271 GO_Central PMID:21873635 PML body organization IDA 2290271 UniProtKB PMID:10779416 , PMID:8643677 positive regulation of apoptotic process involved in mammary gland involution IDA 2290271 UniProtKB PMID:11080164 positive regulation of defense response to virus by host IMP 2290271 UniProtKB PMID:16873256 , PMID:16873257 positive regulation of extrinsic apoptotic signaling pathway IMP 2290271 UniProtKB PMID:21803845 positive regulation of fibroblast proliferation IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 positive regulation of histone deacetylation IDA 2290271 UniProtKB PMID:11259576 positive regulation of nucleic acid-templated transcription IEA GO:0003713 2290271 GOC GO_REF:0000108 positive regulation of protein localization to chromosome, telomeric region IDA 2290271 BHF-UCL PMID:22641345 positive regulation of telomere maintenance IMP 2290271 BHF-UCL PMID:22641345 , PMID:26119943 proteasome-mediated ubiquitin-dependent protein catabolic process IDA 2290271 UniProtKB PMID:22406621 protein import into nucleus IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 protein stabilization IDA 2290271 UniProtKB PMID:12773567 protein targeting IDA 2290271 UniProtKB PMID:11080164 protein targeting IMP 2290271 UniProtKB PMID:15195100 protein-containing complex assembly IDA 2290271 UniProtKB PMID:12915590 regulation of calcium ion transport into cytosol ISS UniProtKB:Q60953 2290271 UniProtKB GO_REF:0000024 regulation of cell adhesion IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 regulation of circadian rhythm ISS UniProtKB:Q60953 2290271 UniProtKB GO_REF:0000024 regulation of double-strand break repair IMP 2290271 UniProtKB PMID:21639834 regulation of protein phosphorylation ISS UniProtKB:Q60953 2290271 UniProtKB GO_REF:0000024 regulation of signal transduction by p53 class mediator TAS 2290271 Reactome Reactome:R-HSA-5633007 regulation of transcription, DNA-templated IMP 2290271 UniProtKB PMID:23007646 regulation of transcription, DNA-templated IBA MGI:MGI:104662 more ... 2290271 GO_Central PMID:21873635 response to cytokine IDA 2290271 BHF-UCL PMID:9412458 response to gamma radiation IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 response to hypoxia IDA 2290271 UniProtKB PMID:16915281 response to UV IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 retinoic acid receptor signaling pathway IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 transforming growth factor beta receptor signaling pathway IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 viral process IEA UniProtKB-KW:KW-0945 2290271 UniProtKB GO_REF:0000037 Cellular Component cytoplasm IDA 2290271 UniProtKB PMID:16778193 more ... cytoplasm IBA PANTHER:PTN002379290 , UniProtKB:P29590 2290271 GO_Central PMID:21873635 cytosol TAS 2290271 Reactome Reactome:R-HSA-1031716 cytosol ISS UniProtKB:Q60953 2290271 UniProtKB GO_REF:0000024 early endosome membrane IEA UniProtKB-SubCell:SL-0093 2290271 UniProtKB GO_REF:0000039 extrinsic component of endoplasmic reticulum membrane ISS UniProtKB:Q60953 2290271 UniProtKB GO_REF:0000024 heterochromatin IEA UniProtKB:Q60953 , ensembl:ENSMUSP000000828162290271 Ensembl GO_REF:0000107 nuclear chromosome, telomeric region IDA 2290271 BHF-UCL PMID:26119943 nuclear matrix IDA 2290271 UniProtKB PMID:11080164 nuclear matrix IBA MGI:MGI:104662 more ... 2290271 GO_Central PMID:21873635 nuclear membrane IDA 2290271 UniProtKB PMID:16778193 nucleolus IDA 2290271 UniProtKB PMID:15195100 , PMID:16778193 nucleoplasm IDA 2290271 UniProtKB PMID:12915590 nucleoplasm TAS 2290271 Reactome Reactome:R-HSA-1031716 more ... nucleus IDA 2290271 UniProtKB PMID:16778193 more ... PML body colocalizes_with IDA 2290271 UniProtKB PMID:10910364 PML body IBA MGI:MGI:104662 more ... 2290271 GO_Central PMID:21873635 PML body IDA 2290271 UniProtKB PMID:11331580 more ... PML body TAS 2290271 HGNC PMID:9230084 Molecular Function cobalt ion binding IDA 2290271 UniProtKB PMID:7729428 DNA binding IEA UniProtKB-KW:KW-0238 2290271 UniProtKB GO_REF:0000037 protein binding IPI UniProtKB:Q06609 2290271 BHF-UCL PMID:22641345 protein binding IPI UniProtKB:Q6N021 2290271 IntAct PMID:29735542 protein binding IPI UniProtKB:G2XKQ0 2290271 UniProt PMID:27211601 protein binding IPI UniProtKB:Q8UN00 2290271 IntAct PMID:22685230 protein binding IPI UniProtKB:Q9ULZ3 2290271 AgBase PMID:24407287 protein binding IPI UniProtKB:P03243-1 2290271 IntAct PMID:20639899 , PMID:25772236 protein binding IPI UniProtKB:P68400 2290271 IntAct PMID:16873060 more ... protein binding IPI UniProtKB:Q9Y2M5 2290271 IntAct PMID:20389280 , PMID:21840486 protein binding IPI UniProtKB:P63165 2290271 IntAct PMID:11948183 more ... protein binding IPI UniProtKB:Q13164 2290271 IntAct PMID:20832753 , PMID:22869143 protein binding IPI UniProtKB:P04637 2290271 IntAct PMID:11080164 more ... protein binding IPI UniProtKB:Q9UER7 2290271 IntAct PMID:10669754 more ... protein binding IPI UniProtKB:O88907 2290271 UniProtKB PMID:22406621 protein binding IPI UniProtKB:Q8WUI4 2290271 UniProtKB PMID:22155184 protein binding IPI UniProtKB:Q64127 2290271 UniProtKB PMID:10610177 protein binding IPI UniProtKB:Q92794 2290271 UniProtKB PMID:23431171 protein binding IPI UniProtKB:P33076 2290271 UniProtKB PMID:23007646 protein binding IPI UniProtKB:O75928 2290271 UniProtKB PMID:22406621 protein binding IPI UniProtKB:O15119 2290271 UniProtKB PMID:22002537 protein binding IPI UniProtKB:P49792 2290271 UniProtKB PMID:22155184 protein binding IPI UniProtKB:Q14191 2290271 UniProtKB PMID:21639834 protein binding IPI UniProtKB:P62913 2290271 UniProtKB PMID:15195100 protein binding IPI UniProtKB:O15379 2290271 UniProtKB PMID:11259576 protein binding IPI UniProtKB:P23769 2290271 UniProtKB PMID:10938104 protein binding IPI UniProtKB:Q9UER7-1 2290271 UniProtKB PMID:10669754 protein binding IPI UniProtKB:P63073 2290271 UniProtKB PMID:11500381 protein binding IPI UniProtKB:Q03014 2290271 UniProtKB PMID:10597310 protein binding IPI UniProtKB:P45481 2290271 UniProtKB PMID:10610177 protein binding IPI UniProtKB:Q92547 2290271 UniProtKB PMID:12773567 protein binding IPI UniProtKB:O96017 2290271 UniProtKB PMID:12402044 protein binding IPI UniProtKB:Q92769 2290271 UniProtKB PMID:11259576 protein binding IPI UniProtKB:Q00987 2290271 IntAct PMID:12915590 , PMID:22869143 protein binding IPI UniProtKB:P63279 2290271 UniProtKB PMID:9885291 protein binding IPI UniProtKB:P14373 2290271 UniProtKB PMID:9570750 protein binding IPI UniProtKB:P06400 2290271 UniProtKB PMID:9448006 protein binding IPI UniProtKB:Q99497 2290271 ParkinsonsUK-UCL PMID:22683601 protein binding IPI UniProtKB:Q13207 2290271 UniProtKB PMID:22002537 protein binding IPI UniProtKB:Q96EB6 2290271 BHF-UCL PMID:12006491 protein binding IPI UniProtKB:P03304:PRO_0000039791 2290271 IntAct PMID:21994459 protein binding IPI UniProtKB:P25788 2290271 IntAct PMID:21988832 protein binding IPI UniProtKB:P25445 2290271 IntAct PMID:21803845 protein binding IPI UniProtKB:P04489 2290271 UniProtKB PMID:16501113 protein binding IPI UniProtKB:P27958:PRO_0000037566 2290271 IntAct PMID:16322229 protein binding IPI UniProtKB:Q05516 2290271 UniProtKB PMID:9294197 protein binding IPI UniProtKB:O14746 2290271 UniProtKB PMID:19567472 protein binding IPI UniProtKB:Q15583 2290271 IntAct PMID:18511908 protein binding IPI UniProtKB:Q8NEV1 2290271 UniProtKB PMID:20625391 protein binding IPI UniProtKB:P14618 2290271 UniProtKB PMID:18298799 protein binding IPI UniProtKB:P42345 2290271 UniProtKB PMID:16915281 protein binding IPI UniProtKB:P05412 2290271 UniProtKB PMID:15626733 protein binding IPI UniProtKB:Q9CXW4 2290271 UniProtKB PMID:15195100 protein binding IPI UniProtKB:Q99607 2290271 UniProtKB PMID:14976184 protein binding IPI UniProtKB:A7UKY0 2290271 UniProtKB PMID:15195100 protein binding IPI UniProtKB:Q13547 2290271 UniProtKB PMID:11259576 protein binding IPI UniProtKB:O35613 2290271 UniProtKB PMID:10684855 protein binding IPI UniProtKB:P54274 2290271 BHF-UCL PMID:22641345 protein binding IPI UniProtKB:Q08999 2290271 UniProtKB PMID:22002537 protein binding IPI UniProtKB:Q96EP1 2290271 UniProtKB PMID:15467728 protein binding IPI UniProtKB:O15055 2290271 UniProtKB PMID:22274616 protein binding IPI UniProtKB:P43356 2290271 UniProtKB PMID:22117195 protein binding IPI UniProtKB:Q96T88 2290271 UniProtKB PMID:22945642 protein binding IPI UniProtKB:Q16254 2290271 UniProtKB PMID:22002537 protein heterodimerization activity IDA 2290271 UniProtKB PMID:7935403 protein homodimerization activity IPI UniProtKB:P29590 2290271 BHF-UCL PMID:9230084 SMAD binding IBA MGI:MGI:104662 , PANTHER:PTN002379290 2290271 GO_Central PMID:21873635 SUMO binding IPI UniProtKB:P61956 2290271 CAFA PMID:17081986 SUMO binding IBA PANTHER:PTN002379290 , UniProtKB:P29590 2290271 GO_Central PMID:21873635 SUMO binding IPI UniProtKB:P63165 2290271 CAFA PMID:17081985 , PMID:17081986 transcription coactivator activity IDA 2290271 UniProtKB PMID:11080164 , PMID:15626733 transcription coactivator activity IBA PANTHER:PTN002379290 , UniProtKB:P29590 2290271 GO_Central PMID:21873635 ubiquitin protein ligase binding IPI UniProtKB:Q00987 2290271 UniProtKB PMID:12915590 zinc ion binding IDA 2290271 UniProtKB PMID:7729428 zinc ion binding IEA InterPro:IPR000315 2290271 InterPro GO_REF:0000002
Gene-Chemical Interaction Annotations
