Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   
Gene: ITPR3 (inositol 1,4,5-trisphosphate receptor type 3) Homo sapiens
Analyze
Symbol: ITPR3
Name: inositol 1,4,5-trisphosphate receptor type 3
Description: Exhibits inositol 1,4,5 trisphosphate binding activity and inositol 1,4,5-trisphosphate-sensitive calcium-release channel activity. Involved in response to calcium ion. Localizes to the endoplasmic reticulum membrane; integral component of plasma membrane; and receptor complex. Implicated in type 1 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: FLJ36205; inositol 1,4,5-triphosphate receptor, type 3; Inositol 1,4,5-trisphosphate receptor type 3 (Type 3 inositol 1,4,5-trisphosphate receptor) (Type 3 InsP3 receptor) (IP3 receptor isoform 3) (InsP3R3); inositol 1,4,5-trisphosphate receptor, type 3; insP3R3; IP3 receptor; IP3R; IP3R 3; IP3R3; type 3 inositol 1,4,5-trisphosphate receptor; type 3 InsP3 receptor
Orthologs:
Mus musculus (house mouse) : Itpr3 (inositol 1,4,5-triphosphate receptor 3)  MGI  Alliance
Rattus norvegicus (Norway rat) : Itpr3 (inositol 1,4,5-trisphosphate receptor, type 3)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Itpr3 (inositol 1,4,5-trisphosphate receptor type 3)
Pan paniscus (bonobo/pygmy chimpanzee) : ITPR3 (inositol 1,4,5-trisphosphate receptor type 3)
Canis lupus familiaris (dog) : ITPR3 (inositol 1,4,5-trisphosphate receptor type 3)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Itpr3 (inositol 1,4,5-trisphosphate receptor type 3)
Sus scrofa (pig) : ITPR3 (inositol 1,4,5-trisphosphate receptor type 3)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38633,621,322 - 33,696,562 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37633,587,951 - 33,664,351 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36633,697,139 - 33,772,329 (+)NCBINCBI36hg18NCBI36
Build 34633,697,321 - 33,772,317NCBI
Celera635,143,559 - 35,218,741 (+)NCBI
Cytogenetic Map6p21.31NCBI
HuRef633,330,927 - 33,406,007 (+)NCBIHuRef
CHM1_1633,591,516 - 33,666,641 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated

Genomics

Comparative Map Data
Position Markers
miRNA Target Status

Expression


Sequence

Nucleotide Sequences
Protein Sequences
Promoters
Clinical Variants

Additional Information

External Database Links
Nomenclature History
 
More on ITPR3
Alliance Gene
NCBI Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 733997
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-11-05
Status: ACTIVE



NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.