CXCL12 (C-X-C motif chemokine ligand 12) - Rat Genome Database
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Gene: CXCL12 (C-X-C motif chemokine ligand 12) Homo sapiens
Analyze
Symbol: CXCL12
Name: C-X-C motif chemokine ligand 12
RGD ID: 737223
HGNC Page HGNC
Description: Exhibits CXCR chemokine receptor binding activity; chemokine activity; and integrin binding activity. Involved in several processes, including integrin activation; negative regulation of apoptotic process; and regulation of leukocyte migration. Localizes to collagen-containing extracellular matrix and extracellular exosome. Implicated in breast carcinoma; diabetic angiopathy; human immunodeficiency virus infectious disease; and type 1 diabetes mellitus. Biomarker of diabetic retinopathy; insulinoma; periodontitis; and type 2 diabetes mellitus.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: chemokine (C-X-C motif) ligand 12; intercrine reduced in hepatomas; IRH; PBSF; pre-B cell growth-stimulating factor; SCYB12; SDF-1a; SDF-1b; SDF1; SDF1A; SDF1B; stromal cell-derived factor 1; TLSF; TLSF-a; TLSF-b; TPAR1
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1044,370,165 - 44,386,493 (-)EnsemblGRCh38hg38GRCh38
GRCh381044,292,088 - 44,385,097 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371044,865,601 - 44,880,545 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361044,185,611 - 44,200,548 (-)NCBINCBI36hg18NCBI36
Build 341044,192,516 - 44,200,551NCBI
Celera1040,869,153 - 40,884,099 (-)NCBI
Cytogenetic Map10q11.21NCBI
HuRef1041,391,945 - 41,406,899 (-)NCBIHuRef
CHM1_11044,904,782 - 44,919,728 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-catechin  (EXP)
(+)-schisandrin B  (ISO)
(25R)-cholest-5-ene-3beta,26-diol  (EXP)
(RS)-coclaurine  (ISO)
(RS)-norcoclaurine  (ISO)
(S)-coclaurine  (ISO)
1,1,1-trichloro-2,2-bis(4-hydroxyphenyl)ethane  (EXP)
1,2-dimethylhydrazine  (ISO)
1,4-benzoquinone  (EXP)
1-bromopropane  (EXP)
1-naphthyl isothiocyanate  (ISO)
1-octadec-9-enoylglycero-3-phosphate  (ISO)
14-Deoxy-11,12-didehydroandrographolide  (EXP)
17alpha-ethynylestradiol  (EXP,ISO)
17beta-estradiol  (EXP,ISO)
17beta-hydroxy-5alpha-androstan-3-one  (EXP)
2,2',4,4',5,5'-hexachlorobiphenyl  (EXP,ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (EXP,ISO)
2,4,6-trinitrobenzenesulfonic acid  (ISO)
2,4-dinitrotoluene  (ISO)
2,6-dinitrotoluene  (ISO)
2-acetamidofluorene  (ISO)
2-amino-2-deoxy-D-glucopyranose  (ISO)
2-hydroxyethyl methacrylate  (EXP)
26-hydroxycholesterol  (EXP)
3,3',4,4',5-pentachlorobiphenyl  (ISO)
3,3',5,5'-tetrabromobisphenol A  (ISO)
3-\{1-[3-(dimethylamino)propyl]-1H-indol-3-yl\}-4-(1H-indol-3-yl)-1H-pyrrole-2,5-dione  (EXP)
3-isobutyl-1-methyl-7H-xanthine  (EXP,ISO)
3-methylcholanthrene  (ISO)
4,4'-diaminodiphenylmethane  (ISO)
4,4'-sulfonyldiphenol  (ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (ISO)
4-hydroxyphenyl retinamide  (ISO)
5-aza-2'-deoxycytidine  (EXP)
5-azacytidine  (EXP)
5-fluorouracil  (ISO)
6-propyl-2-thiouracil  (ISO)
8'-apo-beta,psi-caroten-8'-al  (EXP)
8-Br-cAMP  (EXP,ISO)
afimoxifene  (EXP)
aflatoxin B1  (EXP,ISO)
aldehydo-D-glucosamine  (ISO)
all-trans-retinoic acid  (EXP,ISO)
ammonium chloride  (ISO)
apigenin  (EXP)
arsenous acid  (EXP)
asbestos  (EXP)
asperentin  (ISO)
BAY 60-6583  (ISO)
belinostat  (EXP)
benzene  (ISO)
benzo[a]pyrene  (EXP,ISO)
benzo[a]pyrene diol epoxide I  (EXP)
benzo[e]pyrene  (EXP)
beta-carotene  (EXP)
beta-D-glucosamine  (ISO)
beta-naphthoflavone  (ISO)
bisphenol A  (EXP,ISO)
bisphenol F  (ISO)
bleomycin A2  (ISO)
bucladesine  (ISO)
buta-1,3-diene  (ISO)
butanal  (EXP)
cadmium atom  (EXP)
cadmium dichloride  (EXP)
caffeine  (ISO)
calcium atom  (EXP)
calcium phosphate  (EXP)
calcium(0)  (EXP)
carbon nanotube  (ISO)
ceric oxide  (ISO)
cetrorelix  (EXP)
chloroprene  (ISO)
chloroquine  (ISO)
choline  (ISO)
ciguatoxin CTX1B  (ISO)
ciprofibrate  (ISO)
cisplatin  (ISO)
clobetasol  (ISO)
clofibric acid  (EXP,ISO)
clomiphene  (EXP)
cobalt atom  (ISO)
cobalt dichloride  (EXP,ISO)
copper atom  (ISO)
copper(0)  (ISO)
coumarin  (ISO)
coumestrol  (EXP)
crocidolite asbestos  (ISO)
curcumin  (EXP)
cyclophosphamide  (ISO)
cyclosporin A  (EXP,ISO)
cyproconazole  (ISO)
daidzein  (EXP)
DDT  (EXP)
dexamethasone  (EXP,ISO)
diarsenic trioxide  (EXP)
dibenz[a,h]anthracene  (ISO)
dibutyl phthalate  (ISO)
diethyl malate  (ISO)
diethyl maleate  (ISO)
diethylstilbestrol  (EXP)
dioxygen  (EXP,ISO)
dipyridamole  (ISO)
disodium selenite  (ISO)
diuron  (ISO)
dorsomorphin  (EXP)
edaravone  (ISO)
endosulfan  (ISO)
entinostat  (EXP)
estrone  (EXP)
ethanol  (ISO)
etoposide  (EXP)
fipronil  (ISO)
flutamide  (ISO)
folic acid  (ISO)
fulvestrant  (EXP)
fumonisin B1  (ISO)
furan  (ISO)
gadodiamide hydrate  (EXP)
genistein  (EXP)
glafenine  (ISO)
glyceollin  (EXP)
glycidol  (ISO)
glyphosate  (EXP)
GW 1929  (EXP)
heparin  (EXP)
hexestrol  (EXP)
hydrogen peroxide  (ISO)
hydroquinone  (EXP)
Indeno[1,2,3-cd]pyrene  (EXP)
indometacin  (EXP,ISO)
irinotecan  (EXP)
isotretinoin  (EXP)
leflunomide  (ISO)
lipopolysaccharide  (ISO)
liquiritigenin  (EXP)
luteolin  (ISO)
manganese atom  (ISO)
manganese(0)  (ISO)
manganese(II) chloride  (ISO)
melphalan  (EXP)
mestranol  (EXP)
methamphetamine  (ISO)
methapyrilene  (EXP,ISO)
methotrexate  (EXP)
methoxychlor  (EXP)
methylmercury chloride  (ISO)
mifepristone  (EXP)
ML-7  (EXP)
monodansylcadaverine  (ISO)
mycophenolic acid  (ISO)
mycotoxin  (ISO)
N-acetyl-L-cysteine  (EXP)
N-Acetyl-S-(1,2-dichlorovinyl)-cysteine  (EXP)
N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal  (ISO)
N-methyl-4-phenylpyridinium  (ISO)
N-methyl-N'-nitro-N-nitrosoguanidine  (ISO)
N-nitrosodiethylamine  (ISO)
N-nitrosodimethylamine  (ISO)
naringin  (ISO)
nefazodone  (ISO)
nickel atom  (ISO)
nickel dichloride  (EXP)
nimesulide  (ISO)
nitric oxide  (ISO)
okadaic acid  (ISO)
oxaliplatin  (EXP,ISO)
p-chloromercuribenzoic acid  (EXP)
p-toluidine  (ISO)
panobinostat  (EXP)
paracetamol  (ISO)
PCB138  (ISO)
perfluorooctanoic acid  (ISO)
permethrin  (ISO)
phenobarbital  (ISO)
phorbol 13-acetate 12-myristate  (EXP,ISO)
picene  (EXP)
pioglitazone  (EXP,ISO)
pirinixic acid  (ISO)
potassium dichromate  (ISO)
progesterone  (EXP,ISO)
propanal  (EXP)
propiconazole  (ISO)
raloxifene  (EXP)
resveratrol  (EXP)
ritonavir  (EXP)
rutin  (ISO)
S-butyl-DL-homocysteine (S,R)-sulfoximine  (ISO)
SB 431542  (EXP)
serpentine asbestos  (EXP,ISO)
silicon dioxide  (EXP)
simvastatin  (ISO)
sodium arsenite  (EXP,ISO)
sodium dichromate  (ISO)
Soman  (ISO)
sterigmatocystin  (ISO)
streptozocin  (ISO)
tamoxifen  (EXP,ISO)
telmisartan  (EXP)
Tesaglitazar  (ISO)
tetrachloromethane  (ISO)
tetracycline  (ISO)
tetraphene  (EXP)
thioacetamide  (ISO)
titanium dioxide  (EXP,ISO)
toluene  (ISO)
toluene 2,4-diisocyanate  (ISO)
topotecan  (ISO)
trichostatin A  (EXP)
triclosan  (EXP)
trimellitic anhydride  (ISO)
troglitazone  (ISO)
valproic acid  (EXP,ISO)
vancomycin  (ISO)
vinclozolin  (ISO)
vorinostat  (EXP)
XL147  (ISO)
Y-27632  (EXP)
yohimbine  (ISO)
zalcitabine  (ISO)
zearalenone  (EXP)
zinc atom  (ISO)
zinc(0)  (ISO)
zoledronic acid  (EXP)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adult locomotory behavior  (IEA)
ameboidal-type cell migration  (ISO)
animal organ regeneration  (IEA)
antimicrobial humoral immune response mediated by antimicrobial peptide  (IDA)
axon guidance  (IBA,TAS)
blood circulation  (TAS)
brain development  (ISO)
branching involved in blood vessel morphogenesis  (ISO)
cell adhesion  (TAS)
cell chemotaxis  (IBA,IDA)
cell-cell adhesion  (ISO)
cellular calcium ion homeostasis  (TAS)
cellular response to chemokine  (IMP)
chemokine (C-X-C motif) ligand 12 signaling pathway  (IMP)
chemokine-mediated signaling pathway  (IBA,IDA)
chemotaxis  (TAS)
defense response  (IEA)
detection of mechanical stimulus involved in sensory perception of pain  (IEA)
detection of temperature stimulus involved in sensory perception of pain  (IEA)
dopaminergic neuron differentiation  (ISO)
G protein-coupled receptor signaling pathway  (TAS)
germ cell development  (ISO)
germ cell migration  (ISO)
immune response  (IEA)
induction of positive chemotaxis  (IBA)
integrin activation  (IDA)
killing of cells of other organism  (IDA)
motor neuron axon guidance  (ISO)
negative regulation of cell population proliferation  (ISO)
negative regulation of dendritic cell apoptotic process  (IDA)
negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage  (IDA)
negative regulation of leukocyte tethering or rolling  (IDA)
neuron migration  (IEA)
positive regulation of axon extension involved in axon guidance  (IEA)
positive regulation of calcium ion import  (TAS)
positive regulation of cell adhesion  (IDA)
positive regulation of cell migration  (IBA)
positive regulation of cell population proliferation  (ISO)
positive regulation of chemotaxis  (ISO)
positive regulation of dopamine secretion  (IEA)
positive regulation of endothelial cell proliferation  (IEA)
positive regulation of ERK1 and ERK2 cascade  (ISO)
positive regulation of monocyte chemotaxis  (IDA)
positive regulation of myoblast fusion  (ISO)
positive regulation of neuron differentiation  (IEA)
positive regulation of protein kinase B signaling  (ISO)
positive regulation of T cell migration  (IDA)
regulation of actin polymerization or depolymerization  (TAS)
regulation of calcium ion transport  (ISO)
regulation of cell migration  (ISO)
response to heat  (IEA)
response to hypoxia  (IEA)
response to mechanical stimulus  (ISO)
response to peptide hormone  (IEA)
response to radiation  (IEA)
response to ultrasound  (IEA)
response to virus  (TAS)
signal transduction  (TAS)
T cell chemotaxis  (IDA)
T cell proliferation  (ISO)
telencephalon cell migration  (IEA)
viral process  (IEA)

Cellular Component

Molecular Function

Molecular Pathway Annotations     Click to see Annotation Detail View
References

References - curated
1. Abe D, etal., J Periodontal Res. 2011 Jun;46(3):345-53. doi: 10.1111/j.1600-0765.2011.01349.x. Epub 2011 Mar 7.
2. Badillo AT, etal., J Surg Res. 2007 Nov;143(1):35-42.
3. Butler JM, etal., J Clin Invest. 2005 Jan;115(1):86-93.
4. Dubois-Laforgue D, etal., Diabetes. 2001 May;50(5):1211-3.
5. Fujinaka H, etal., J Nephrol. 2007 May-Jun;20(3):357-63.
6. Havens AM, etal., J Periodontol. 2008 May;79(5):845-53.
7. Hu XM, etal., Sci Rep. 2017 Jun 21;7(1):4005. doi: 10.1038/s41598-017-04198-3.
8. Humpert PM, etal., Clin Chem. 2006 Jun;52(6):1206-8.
9. Ide A, etal., Hum Immunol. 2003 Oct;64(10):973-8.
10. Ilhan A, etal., Mol Cell Endocrinol. 2009 Jan 27;298(1-2):1-10. Epub 2008 Oct 22.
11. Jung KH, etal., Epilepsia. 2009 Mar;50(3):537-49. Epub 2008 Nov 20.
12. Lai P, etal., Graefes Arch Clin Exp Ophthalmol. 2008 Dec;246(12):1707-13. Epub 2008 Aug 16.
13. Leng Q, etal., BMC Immunol. 2008 Sep 15;9:51.
14. Li XQ, etal., PLoS One. 2016 Oct 19;11(10):e0163807. doi: 10.1371/journal.pone.0163807. eCollection 2016.
15. Lin Y, etal., Fertil Steril. 2008 Apr 1.
16. Loader B, etal., Otol Neurotol. 2008 Sep;29(6):739-44.
17. Matin K, etal., Immunology. 2002 Oct;107(2):222-32.
18. Oh SB, etal., J Neurosci. 2001 Jul 15;21(14):5027-35.
19. OMIM Disease Annotation Pipeline
20. Pillarisetti K and Gupta SK, Inflammation 2001 Oct;25(5):293-300.
21. Pipeline to import KEGG annotations from KEGG into RGD
22. Pipeline to import Pathway Interaction Database annotations from NCI into RGD
23. Razmkhah M, etal., Cancer Lett. 2005 Jul 28;225(2):261-6. Epub 2004 Dec 13.
24. RGD automated import pipeline for ClinVar variants, variant-to-disease annotations and gene-to-disease annotations
25. RGD automated import pipeline for gene-chemical interactions
26. Roy I, etal., Cancer Res. 2015 Sep 1;75(17):3529-42. doi: 10.1158/0008-5472.CAN-14-2645.
27. Shigihara T, etal., Ann N Y Acad Sci. 2003 Nov;1005:328-31.
28. Shimode K, etal., Tissue Eng Part A. 2009 Feb 27.
29. Sun YX, etal., J Cell Biochem. 2003 Jun 1;89(3):462-73.
30. Wang Y, etal., Brain Res. 2008 Feb 21;1195:104-12. Epub 2007 Dec 14.
31. Wang Y, etal., Brain Res. 2014 Aug 5;1575:78-86. doi: 10.1016/j.brainres.2014.05.035. Epub 2014 Jun 9.
32. Wei FY, etal., PLoS One. 2014 Sep 2;9(9):e106722. doi: 10.1371/journal.pone.0106722. eCollection 2014.
33. Yano T, etal., Diabetes. 2007 Dec;56(12):2946-57. Epub 2007 Sep 18.
34. Yuan YZ, etal., Zhonghua Yan Ke Za Zhi. 2007 Oct;43(10):912-6.
35. Zhuang Y, etal., Chin Med J (Engl). 2009 Jan 20;122(2):183-7.
Additional References at PubMed
PMID:7490086   PMID:8752280   PMID:8752281   PMID:8976200   PMID:9384579   PMID:9558100   PMID:9601645   PMID:9618518   PMID:9653130   PMID:9710254   PMID:9743377   PMID:9744279  
PMID:9826729   PMID:9828130   PMID:10196252   PMID:10198043   PMID:10233851   PMID:10358157   PMID:10430052   PMID:10438529   PMID:10486323   PMID:10491003   PMID:10550315   PMID:10570282  
PMID:10582593   PMID:10583963   PMID:10600606   PMID:10620615   PMID:10644702   PMID:10772939   PMID:10802710   PMID:10820198   PMID:10872839   PMID:10925302   PMID:10954912   PMID:11023492  
PMID:11023498   PMID:11027346   PMID:11083865   PMID:11162626   PMID:11241273   PMID:11242036   PMID:11287575   PMID:11328308   PMID:11389173   PMID:11390394   PMID:11504955   PMID:11571304  
PMID:11591806   PMID:11693435   PMID:11694103   PMID:11709782   PMID:11729511   PMID:11830456   PMID:11860793   PMID:11860823   PMID:11865429   PMID:11867624   PMID:11870628   PMID:11877260  
PMID:11884424   PMID:11898620   PMID:11912162   PMID:11929756   PMID:11950063   PMID:11953881   PMID:11964548   PMID:11988632   PMID:11994484   PMID:12001056   PMID:12004084   PMID:12032878  
PMID:12034737   PMID:12036856   PMID:12036857   PMID:12044982   PMID:12068293   PMID:12088413   PMID:12135674   PMID:12149427   PMID:12176869   PMID:12201365   PMID:12215924   PMID:12239139  
PMID:12239174   PMID:12354773   PMID:12370187   PMID:12393569   PMID:12393663   PMID:12436194   PMID:12444109   PMID:12477932   PMID:12482395   PMID:12485835   PMID:12511407   PMID:12557141  
PMID:12571520   PMID:12591904   PMID:12605695   PMID:12692604   PMID:12702590   PMID:12705474   PMID:12730110   PMID:12750733   PMID:12766157   PMID:12769333   PMID:12775566   PMID:12782716  
PMID:12783211   PMID:12783869   PMID:12787886   PMID:12817019   PMID:12834106   PMID:12860456   PMID:12865405   PMID:12882655   PMID:12907449   PMID:12907452   PMID:12949249   PMID:12953097  
PMID:12960279   PMID:13130466   PMID:14525775   PMID:14555820   PMID:14600836   PMID:14623290   PMID:14624371   PMID:14630801   PMID:14684377   PMID:14688392   PMID:14757413   PMID:14764445  
PMID:14871974   PMID:14973260   PMID:14995074   PMID:15021309   PMID:15026312   PMID:15033938   PMID:15048928   PMID:15059845   PMID:15076247   PMID:15113900   PMID:15140377   PMID:15146553  
PMID:15164054   PMID:15166527   PMID:15183061   PMID:15192272   PMID:15223017   PMID:15235108   PMID:15236615   PMID:15240098   PMID:15286810   PMID:15292258   PMID:15302103   PMID:15319853  
PMID:15328206   PMID:15345598   PMID:15358596   PMID:15381727   PMID:15454484   PMID:15467730   PMID:15475370   PMID:15489334   PMID:15504551   PMID:15533859   PMID:15536181   PMID:15548717  
PMID:15575507   PMID:15585097   PMID:15588513   PMID:15608062   PMID:15611059   PMID:15630457   PMID:15639953   PMID:15641073   PMID:15677562   PMID:15681827   PMID:15699497   PMID:15701832  
PMID:15707999   PMID:15710459   PMID:15718415   PMID:15718416   PMID:15728464   PMID:15748209   PMID:15753365   PMID:15754978   PMID:15793201   PMID:15805285   PMID:15808852   PMID:15809737  
PMID:15819887   PMID:15831676   PMID:15840658   PMID:15843590   PMID:15844659   PMID:15857508   PMID:15872091   PMID:15882617   PMID:15888687   PMID:15917309   PMID:15921680   PMID:15955592  
PMID:15965952   PMID:15972632   PMID:15972662   PMID:15980693   PMID:15987445   PMID:15998835   PMID:16033774   PMID:16107333   PMID:16112086   PMID:16114056   PMID:16123688   PMID:16148115  
PMID:16159864   PMID:16177829   PMID:16188969   PMID:16206074   PMID:16227796   PMID:16249700   PMID:16261210   PMID:16284526   PMID:16286054   PMID:16286055   PMID:16306115   PMID:16343773  
PMID:16344560   PMID:16385451   PMID:16480760   PMID:16485782   PMID:16489019   PMID:16494621   PMID:16503409   PMID:16507142   PMID:16529059   PMID:16611258   PMID:16626895   PMID:16648972  
PMID:16703398   PMID:16756955   PMID:16779827   PMID:16782208   PMID:16818471   PMID:16823836   PMID:16823956   PMID:16857992   PMID:16865553   PMID:16875673   PMID:16905744   PMID:16923552  
PMID:16929176   PMID:16943240   PMID:16948134   PMID:16948905   PMID:16960937   PMID:16964435   PMID:16977794   PMID:16990599   PMID:17015707   PMID:17034033   PMID:17038526   PMID:17038674  
PMID:17046575   PMID:17056591   PMID:17075134   PMID:17082613   PMID:17099730   PMID:17119115   PMID:17143542   PMID:17148615   PMID:17174272   PMID:17197116   PMID:17237407   PMID:17240189  
PMID:17245764   PMID:17264079   PMID:17340464   PMID:17355795   PMID:17357154   PMID:17379424   PMID:17393416   PMID:17409218   PMID:17413295   PMID:17456315   PMID:17461449   PMID:17507482  
PMID:17510563   PMID:17530707   PMID:17530998   PMID:17532557   PMID:17550983   PMID:17559806   PMID:17560067   PMID:17572689   PMID:17604544   PMID:17631494   PMID:17634424   PMID:17634449  
PMID:17650669   PMID:17653321   PMID:17653799   PMID:17681365   PMID:17687643   PMID:17706641   PMID:17724466   PMID:17768666   PMID:17784832   PMID:17785557   PMID:17805324   PMID:17846797  
PMID:17878755   PMID:17894415   PMID:17898317   PMID:17914737   PMID:17916907   PMID:17923814   PMID:17949547   PMID:17950696   PMID:17964973   PMID:17982648   PMID:18040858   PMID:18060801  
PMID:18086932   PMID:18097955   PMID:18191726   PMID:18205260   PMID:18206727   PMID:18223219   PMID:18227351   PMID:18240029   PMID:18267010   PMID:18275857   PMID:18276777   PMID:18281050  
PMID:18292211   PMID:18292502   PMID:18292939   PMID:18308860   PMID:18310089   PMID:18316470   PMID:18317966   PMID:18323525   PMID:18337451   PMID:18339898   PMID:18351386   PMID:18354239  
PMID:18357387   PMID:18365549   PMID:18383856   PMID:18386165   PMID:18391751   PMID:18443596   PMID:18448428   PMID:18448868   PMID:18469140   PMID:18487224   PMID:18502034   PMID:18512766  
PMID:18521742   PMID:18549608   PMID:18556651   PMID:18558091   PMID:18563594   PMID:18575756   PMID:18577527   PMID:18577758   PMID:18599607   PMID:18632989   PMID:18633131   PMID:18634924  
PMID:18648536   PMID:18653785   PMID:18670789   PMID:18687671   PMID:18692524   PMID:18698020   PMID:18707241   PMID:18709948   PMID:18757300   PMID:18760838   PMID:18760839   PMID:18763111  
PMID:18774388   PMID:18774952   PMID:18775666   PMID:18781098   PMID:18788547   PMID:18799424   PMID:18802065   PMID:18814143   PMID:18829537   PMID:18836306   PMID:18845960   PMID:18851783  
PMID:18855658   PMID:18924211   PMID:18928397   PMID:18928845   PMID:18930992   PMID:18936436   PMID:18949410   PMID:18954402   PMID:18954561   PMID:18974840   PMID:19017978   PMID:19019853  
PMID:19028820   PMID:19032065   PMID:19035451   PMID:19059114   PMID:19064579   PMID:19074885   PMID:19082444   PMID:19115008   PMID:19124913   PMID:19131662   PMID:19139298   PMID:19196101  
PMID:19198609   PMID:19199057   PMID:19215683   PMID:19247692   PMID:19252530   PMID:19260802   PMID:19263529   PMID:19280118   PMID:19282275   PMID:19285061   PMID:19287206   PMID:19289100  
PMID:19295169   PMID:19302975   PMID:19307591   PMID:19327121   PMID:19335218   PMID:19336886   PMID:19339694   PMID:19342158   PMID:19372622   PMID:19373784   PMID:19379578   PMID:19381432  
PMID:19394082   PMID:19409379   PMID:19438749   PMID:19443661   PMID:19460858   PMID:19472013   PMID:19476565   PMID:19496172   PMID:19497995   PMID:19500134   PMID:19501493   PMID:19508998  
PMID:19513623   PMID:19520808   PMID:19521120   PMID:19523923   PMID:19526283   PMID:19550128   PMID:19551455   PMID:19559392   PMID:19563077   PMID:19568410   PMID:19601773   PMID:19605814  
PMID:19615218   PMID:19615279   PMID:19639049   PMID:19641037   PMID:19646633   PMID:19654580   PMID:19660434   PMID:19661268   PMID:19669591   PMID:19672298   PMID:19692460   PMID:19695308  
PMID:19700239   PMID:19717493   PMID:19718053   PMID:19745163   PMID:19765831   PMID:19773382   PMID:19774645   PMID:19788587   PMID:19794961   PMID:19808652   PMID:19816012   PMID:19821058  
PMID:19825996   PMID:19826039   PMID:19826912   PMID:19834823   PMID:19837984   PMID:19851296   PMID:19878731   PMID:19885584   PMID:19913121   PMID:19917679   PMID:19921580   PMID:19923906  
PMID:19927352   PMID:19942750   PMID:19958843   PMID:20015878   PMID:20015995   PMID:20018929   PMID:20020198   PMID:20025867   PMID:20028644   PMID:20036838   PMID:20038229   PMID:20067991  
PMID:20072657   PMID:20077567   PMID:20084476   PMID:20088916   PMID:20102637   PMID:20104779   PMID:20109227   PMID:20109310   PMID:20118565   PMID:20133349   PMID:20134207   PMID:20141446  
PMID:20145264   PMID:20163833   PMID:20177148   PMID:20177796   PMID:20181695   PMID:20182908   PMID:20196627   PMID:20198315   PMID:20206813   PMID:20237496   PMID:20299965   PMID:20305788  
PMID:20331475   PMID:20348095   PMID:20362069   PMID:20383584   PMID:20388788   PMID:20388803   PMID:20392929   PMID:20406099   PMID:20411675   PMID:20414828   PMID:20442634   PMID:20462600  
PMID:20484957   PMID:20494937   PMID:20497701   PMID:20501749   PMID:20518834   PMID:20530467   PMID:20531015   PMID:20536507   PMID:20540706   PMID:20558135   PMID:20563451   PMID:20563655  
PMID:20585037   PMID:20585996   PMID:20603037   PMID:20609598   PMID:20622011   PMID:20622326   PMID:20628086   PMID:20629629   PMID:20631377   PMID:20634887   PMID:20637871   PMID:20646340  
PMID:20661426   PMID:20694560   PMID:20695076   PMID:20725607   PMID:20728717   PMID:20738937   PMID:20802378   PMID:20817073   PMID:20835359   PMID:20851290   PMID:20854168   PMID:20865359  
PMID:20869048   PMID:20877573   PMID:20887389   PMID:20889568   PMID:20923761   PMID:20929726   PMID:20967243   PMID:20970672   PMID:20971364   PMID:21041659   PMID:21059341   PMID:21071025  
PMID:21080209   PMID:21082982   PMID:21087507   PMID:21091093   PMID:21132258   PMID:21147466   PMID:21148034   PMID:21158728   PMID:21179442   PMID:21182836   PMID:21186999   PMID:21257825  
PMID:21292343   PMID:21296802   PMID:21298365   PMID:21304904   PMID:21312072   PMID:21349176   PMID:21349998   PMID:21357602   PMID:21361865   PMID:21367627   PMID:21372218   PMID:21378990  
PMID:21396623   PMID:21410972   PMID:21435112   PMID:21440782   PMID:21442287   PMID:21444670   PMID:21459858   PMID:21463876   PMID:21465475   PMID:21470957   PMID:21484857   PMID:21487523  
PMID:21506920   PMID:21518481   PMID:21521526   PMID:21527066   PMID:21567400   PMID:21584490   PMID:21592819   PMID:21602126   PMID:21607621   PMID:21607655   PMID:21618080   PMID:21623830  
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PMID:21802105   PMID:21802140   PMID:21818756   PMID:21840752   PMID:21853036   PMID:21853930   PMID:21856785   PMID:21856938   PMID:21868522   PMID:21873635   PMID:21878545   PMID:21878648  
PMID:21906588   PMID:21906874   PMID:21909361   PMID:21910857   PMID:21921288   PMID:21948620   PMID:21951424   PMID:21953583   PMID:21960286   PMID:21964561   PMID:21968974   PMID:21988832  
PMID:21994039   PMID:22008312   PMID:22015231   PMID:22025313   PMID:22025564   PMID:22044645   PMID:22066471   PMID:22071114   PMID:22074556   PMID:22075627   PMID:22077991   PMID:22088972  
PMID:22092872   PMID:22095608   PMID:22101518   PMID:22114110   PMID:22125123   PMID:22127289   PMID:22128293   PMID:22142194   PMID:22166550   PMID:22169298   PMID:22169299   PMID:22173290  
PMID:22200847   PMID:22220212   PMID:22220905   PMID:22228277   PMID:22232208   PMID:22245379   PMID:22253872   PMID:22270883   PMID:22301555   PMID:22311941   PMID:22333149   PMID:22336440  
PMID:22362916   PMID:22370717   PMID:22386691   PMID:22415233   PMID:22427929   PMID:22430135   PMID:22450749   PMID:22457824   PMID:22469823   PMID:22473778   PMID:22490648   PMID:22492017  
PMID:22495096   PMID:22496601   PMID:22513751   PMID:22526457   PMID:22529914   PMID:22535492   PMID:22549778   PMID:22549810   PMID:22553346   PMID:22554649   PMID:22568557   PMID:22581230  
PMID:22613469   PMID:22664794   PMID:22670173   PMID:22675496   PMID:22683307   PMID:22688512   PMID:22690919   PMID:22699677   PMID:22704519   PMID:22710983   PMID:22727731   PMID:22736769  
PMID:22738089   PMID:22751460   PMID:22753620   PMID:22762525   PMID:22767589   PMID:22779681   PMID:22784557   PMID:22842611   PMID:22844345   PMID:22846168   PMID:22848341   PMID:22885527  
PMID:22905867   PMID:22916293   PMID:22932666   PMID:22939870   PMID:22952422   PMID:22954308   PMID:22954782   PMID:22962615   PMID:22975476   PMID:22978759   PMID:22987307   PMID:22995914  
PMID:23023114   PMID:23039915   PMID:23042661   PMID:23053994   PMID:23070788   PMID:23071112   PMID:23078136   PMID:23098564   PMID:23129313   PMID:23133664   PMID:23143873   PMID:23148226  
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PMID:23325742   PMID:23335032   PMID:23344887   PMID:23376485   PMID:23381805   PMID:23395387   PMID:23434321   PMID:23454481   PMID:23468253   PMID:23473997   PMID:23495012   PMID:23499762  
PMID:23502337   PMID:23526079   PMID:23531450   PMID:23533145   PMID:23538388   PMID:23543442   PMID:23544621   PMID:23563306   PMID:23571274   PMID:23586735   PMID:23588307   PMID:23591873  
PMID:23599431   PMID:23602049   PMID:23615182   PMID:23619587   PMID:23620790   PMID:23623275   PMID:23637121   PMID:23645563   PMID:23653000   PMID:23666823   PMID:23669361   PMID:23701640  
PMID:23702796   PMID:23710557   PMID:23711392   PMID:23712777   PMID:23734232   PMID:23802178   PMID:23812037   PMID:23869217   PMID:23880174   PMID:23895705   PMID:23901140   PMID:23924922  
PMID:23932459   PMID:23935395   PMID:23985752   PMID:24009233   PMID:24014104   PMID:24015267   PMID:24021782   PMID:24022841   PMID:24024210   PMID:24024928   PMID:24025971   PMID:24032722  
PMID:24033610   PMID:24038789   PMID:24079738   PMID:24085800   PMID:24086760   PMID:24091662   PMID:24094005   PMID:24097873   PMID:24102302   PMID:24116850   PMID:24157575   PMID:24174685  
PMID:24175834   PMID:24184476   PMID:24218400   PMID:24238971   PMID:24262325   PMID:24277075   PMID:24282276   PMID:24291546   PMID:24354491   PMID:24361877   PMID:24372262   PMID:24381939  
PMID:24407584   PMID:24416254   PMID:24430363   PMID:24450273   PMID:24465621   PMID:24480462   PMID:24486245   PMID:24492963   PMID:24498095   PMID:24516346   PMID:24534089   PMID:24554482  
PMID:24561124   PMID:24574213   PMID:24584347   PMID:24586072   PMID:24594697   PMID:24600982   PMID:24614402   PMID:24637920   PMID:24658853   PMID:24667918   PMID:24687413   PMID:24704323  
PMID:24708339   PMID:24718687   PMID:24722947   PMID:24751515   PMID:24761914   PMID:24762228   PMID:24799056   PMID:24806942   PMID:24810923   PMID:24819308   PMID:24825098   PMID:24834915  
PMID:24839815   PMID:24853339   PMID:24870556   PMID:24877105   PMID:24887021   PMID:24906407   PMID:24909174   PMID:24913264   PMID:24929539   PMID:24934367   PMID:24940843   PMID:24950016  
PMID:24950177   PMID:24970800   PMID:24982366   PMID:25025568   PMID:25029540   PMID:25037231   PMID:25041836   PMID:25042571   PMID:25084358   PMID:25085362   PMID:25118993   PMID:25121739  
PMID:25150002   PMID:25150783   PMID:25199050   PMID:25220301   PMID:25237195   PMID:25241658   PMID:25268356   PMID:25283599   PMID:25297929   PMID:25305322   PMID:25310198   PMID:25312253  
PMID:25313609   PMID:25344664   PMID:25359136   PMID:25359780   PMID:25388055   PMID:25393253   PMID:25400739   PMID:25400746   PMID:25407240   PMID:25433721   PMID:25446160   PMID:25450979  
PMID:25460081   PMID:25461253   PMID:25461737   PMID:25471741   PMID:25474514   PMID:25482641   PMID:25495026   PMID:25504108   PMID:25504440   PMID:25509878   PMID:25526031   PMID:25557636  
PMID:25560580   PMID:25586789   PMID:25601176   PMID:25605248   PMID:25609203   PMID:25619477   PMID:25620615   PMID:25660395   PMID:25672413   PMID:25689618   PMID:25744829   PMID:25748833  
PMID:25753525   PMID:25785610   PMID:25797207   PMID:25800732   PMID:25803672   PMID:25809793   PMID:25810367   PMID:25815440   PMID:25820929   PMID:25839711   PMID:25839939   PMID:25843954  
PMID:25853481   PMID:25860928   PMID:25872129   PMID:25884570   PMID:25896762   PMID:25897806   PMID:25920609   PMID:25955316   PMID:25957946   PMID:25966814   PMID:25976655   PMID:25982843  
PMID:25995033   PMID:25997540   PMID:26008895   PMID:26026718   PMID:26044561   PMID:26049754   PMID:26058075   PMID:26072067   PMID:26082290   PMID:26096543   PMID:26100110   PMID:26100385  
PMID:26103953   PMID:26130416   PMID:26133117   PMID:26166636   PMID:26168882   PMID:26188201   PMID:26191295   PMID:26205534   PMID:26212341   PMID:26231656   PMID:26232325   PMID:26235278  
PMID:26276357   PMID:26277915   PMID:26296527   PMID:26324845   PMID:26338423   PMID:26349988   PMID:26374452   PMID:26398122   PMID:26406413   PMID:26408542   PMID:26413812   PMID:26414794  
PMID:26435001   PMID:26441035   PMID:26453693   PMID:26463123   PMID:26490988   PMID:26538086   PMID:26552750   PMID:26560447   PMID:26567118   PMID:26587874   PMID:26602164   PMID:26607439  
PMID:26608373   PMID:26631033   PMID:26678887   PMID:26710799   PMID:26715277   PMID:26718114   PMID:26721717   PMID:26722422   PMID:26722521   PMID:26727165   PMID:26780459   PMID:26782381  
PMID:26782415   PMID:26782945   PMID:26806456   PMID:26806619   PMID:26818832   PMID:26847706   PMID:26851944   PMID:26859597   PMID:26878134   PMID:26896000   PMID:26936919   PMID:26936935  
PMID:26952837   PMID:26970955   PMID:26976451   PMID:27018596   PMID:27041792   PMID:27055858   PMID:27058821   PMID:27067482   PMID:27082011   PMID:27147244   PMID:27154815   PMID:27163878  
PMID:27173875   PMID:27175473   PMID:27188867   PMID:27196738   PMID:27220474   PMID:27226569   PMID:27238143   PMID:27265091   PMID:27269177   PMID:27282562   PMID:27300512   PMID:27309347  
PMID:27370398   PMID:27392463   PMID:27400149   PMID:27434301   PMID:27439769   PMID:27462860   PMID:27463607   PMID:27471912   PMID:27484185   PMID:27489286   PMID:27503909   PMID:27542220  
PMID:27542769   PMID:27556030   PMID:27556182   PMID:27566567   PMID:27593937   PMID:27597234   PMID:27607427   PMID:27650618   PMID:27669436   PMID:27693460   PMID:27697997   PMID:27697999  
PMID:27713493   PMID:27716367   PMID:27729562   PMID:27775742   PMID:27803285   PMID:27832196   PMID:27894110   PMID:27913861   PMID:27943613   PMID:27959395   PMID:27996037   PMID:28001450  
PMID:28010141   PMID:28032520   PMID:28040478   PMID:28051881   PMID:28055968   PMID:28067275   PMID:28072855   PMID:28074045   PMID:28074071   PMID:28099683   PMID:28102846   PMID:28115158  
PMID:28131784   PMID:28159982   PMID:28176874   PMID:28186979   PMID:28193907   PMID:28202459   PMID:28236026   PMID:28239742   PMID:28246930   PMID:28272462   PMID:28277316   PMID:28281844  
PMID:28295006   PMID:28325822   PMID:28336327   PMID:28360196   PMID:28381538   PMID:28402926   PMID:28418886   PMID:28475003   PMID:28478797   PMID:28487111   PMID:28526531   PMID:28533662  
PMID:28536953   PMID:28559386   PMID:28562124   PMID:28614256   PMID:28619846   PMID:28621237   PMID:28623786   PMID:28639900   PMID:28650670   PMID:28716707   PMID:28774348   PMID:28811579  
PMID:28811711   PMID:28842468   PMID:28852723   PMID:28855206   PMID:28860570   PMID:28961998   PMID:29022185   PMID:29032612   PMID:29050986   PMID:29061496   PMID:29105376   PMID:29207021  
PMID:29288743   PMID:29301984   PMID:29304539   PMID:29305742   PMID:29316404   PMID:29369549   PMID:29381400   PMID:29414663   PMID:29420545   PMID:29431639   PMID:29433559   PMID:29436696  
PMID:29472636   PMID:29508174   PMID:29516917   PMID:29557746   PMID:29568895   PMID:29581126   PMID:29620151   PMID:29693336   PMID:29735547   PMID:29739049   PMID:29741398   PMID:29758548  
PMID:29800557   PMID:29893194   PMID:29926386   PMID:30012324   PMID:30015971   PMID:30021884   PMID:30037369   PMID:30053458   PMID:30180964   PMID:30182340   PMID:30182568   PMID:30197351  
PMID:30227860   PMID:30253706   PMID:30259564   PMID:30266500   PMID:30320394   PMID:30337520   PMID:30340825   PMID:30428473   PMID:30447648   PMID:30483878   PMID:30489503   PMID:30642980  
PMID:30664157   PMID:30685602   PMID:30692148   PMID:30693694   PMID:30760134   PMID:30787324   PMID:30816272   PMID:30826602   PMID:30830550   PMID:30832753   PMID:30853598   PMID:30857971  
PMID:30864829   PMID:30865486   PMID:30953364   PMID:31071315   PMID:31173219   PMID:31177127   PMID:31186083   PMID:31273931   PMID:31294628   PMID:31324252   PMID:31336263   PMID:31361379  
PMID:31362469   PMID:31397035   PMID:31412792   PMID:31421626   PMID:31445707   PMID:31494797   PMID:31500630   PMID:31506383   PMID:31520606   PMID:31534540   PMID:31540474   PMID:31559838  
PMID:31650642   PMID:31650891   PMID:31658727   PMID:31662443   PMID:31700087   PMID:31752959   PMID:31804579   PMID:31862910   PMID:31874343   PMID:31914631   PMID:31931030   PMID:31933163  
PMID:32020550   PMID:32035133   PMID:32046406   PMID:32156548   PMID:32165289   PMID:32271748   PMID:32303038   PMID:32346064   PMID:32374043   PMID:32401536   PMID:32404985   PMID:32691567  
PMID:32918875   PMID:33067959   PMID:33228346   PMID:33283727  


Genomics

Comparative Map Data
CXCL12
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1044,370,165 - 44,386,493 (-)EnsemblGRCh38hg38GRCh38
GRCh381044,292,088 - 44,385,097 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371044,865,601 - 44,880,545 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361044,185,611 - 44,200,548 (-)NCBINCBI36hg18NCBI36
Build 341044,192,516 - 44,200,551NCBI
Celera1040,869,153 - 40,884,099 (-)NCBI
Cytogenetic Map10q11.21NCBI
HuRef1041,391,945 - 41,406,899 (-)NCBIHuRef
CHM1_11044,904,782 - 44,919,728 (-)NCBICHM1_1
Cxcl12
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm396117,145,496 - 117,158,329 (+)NCBIGRCm39mm39
GRCm386117,168,535 - 117,181,368 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl6117,168,535 - 117,181,367 (+)EnsemblGRCm38mm10GRCm38
MGSCv376117,118,553 - 117,131,386 (+)NCBIGRCm37mm9NCBIm37
MGSCv366117,134,182 - 117,146,986 (+)NCBImm8
Celera6118,991,272 - 119,004,105 (+)NCBICelera
Cytogenetic Map6F1NCBI
cM Map654.81NCBI
Cxcl12
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Rnor_6.04149,261,044 - 149,273,891 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl4149,261,044 - 149,273,891 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.04215,195,689 - 215,208,536 (+)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.44153,503,576 - 153,516,423 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.14153,748,473 - 153,755,186 (+)NCBI
Celera4139,267,343 - 139,280,188 (+)NCBICelera
Cytogenetic Map4q42NCBI
Cxcl12
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0 EnsemblNW_0049555461,929,269 - 1,941,690 (-)EnsemblChiLan1.0
ChiLan1.0NW_0049555461,929,269 - 1,941,690 (-)NCBIChiLan1.0ChiLan1.0
CXCL12
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.11044,476,962 - 44,564,231 (-)NCBIpanpan1.1PanPan1.1panPan2
Mhudiblu_PPA_v01041,296,975 - 41,384,864 (-)NCBIMhudiblu_PPA_v0panPan3
CXCL12
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1282,895,916 - 2,903,543 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Cxcl12
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
SpeTri2.0NW_0049366174,224,131 - 4,239,080 (-)NCBISpeTri2.0SpeTri2.0SpeTri2.0
CXCL12
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl1491,516,429 - 91,552,766 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.11491,516,383 - 91,543,857 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.21499,990,204 - 100,017,171 (+)NCBISscrofa10.2Sscrofa10.2susScr3
CXCL12
(Chlorocebus sabaeus - African green monkey)
Vervet AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.1 Ensembl940,011,439 - 40,020,494 (-)Ensembl
ChlSab1.1940,005,580 - 40,020,513 (-)NCBI
Cxcl12
(Heterocephalus glaber - naked mole-rat)
Molerat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_0046249221,261,228 - 1,273,755 (-)NCBI

Position Markers
G17474  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371044,876,810 - 44,877,003UniSTSGRCh37
Build 361044,196,816 - 44,197,009RGDNCBI36
Celera1040,880,363 - 40,880,556RGD
Cytogenetic Map10q11.1UniSTS
HuRef1041,403,159 - 41,403,352UniSTS
G30000  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371044,865,596 - 44,865,717UniSTSGRCh37
Build 361044,185,602 - 44,185,723RGDNCBI36
Celera1040,869,144 - 40,869,265RGD
Cytogenetic Map10q11.1UniSTS
HuRef1041,391,940 - 41,392,061UniSTS
SGC33589  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371044,867,248 - 44,867,397UniSTSGRCh37
Build 361044,187,254 - 44,187,403RGDNCBI36
Celera1040,870,796 - 40,870,945RGD
Cytogenetic Map10q11.1UniSTS
HuRef1041,393,592 - 41,393,741UniSTS
GeneMap99-GB4 RH Map10267.27UniSTS
Whitehead-RH Map10316.3UniSTS
NCBI RH Map10591.5UniSTS
D10S1350E  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371044,865,728 - 44,865,860UniSTSGRCh37
Build 361044,185,734 - 44,185,866RGDNCBI36
Celera1040,869,276 - 40,869,408RGD
Cytogenetic Map10q11.1UniSTS
HuRef1041,392,072 - 41,392,204UniSTS
RH44690  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371044,867,351 - 44,867,480UniSTSGRCh37
Build 361044,187,357 - 44,187,486RGDNCBI36
Celera1040,870,899 - 40,871,028RGD
Cytogenetic Map10q11.1UniSTS
HuRef1041,393,695 - 41,393,824UniSTS
GeneMap99-GB4 RH Map10261.73UniSTS
NCBI RH Map10591.5UniSTS
D10S2188  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371044,868,238 - 44,868,350UniSTSGRCh37
Build 361044,188,244 - 44,188,356RGDNCBI36
Celera1040,871,786 - 40,871,898RGD
Cytogenetic Map10q11.1UniSTS
HuRef1041,394,582 - 41,394,694UniSTS
GeneMap99-GB4 RH Map10261.82UniSTS
Whitehead-RH Map10337.9UniSTS
Whitehead-YAC Contig Map10 UniSTS
NCBI RH Map10591.5UniSTS
SGC33789  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371044,872,998 - 44,873,127UniSTSGRCh37
Build 361044,193,004 - 44,193,133RGDNCBI36
Celera1040,876,551 - 40,876,680RGD
Cytogenetic Map10q11.1UniSTS
HuRef1041,399,347 - 41,399,476UniSTS
GeneMap99-GB4 RH Map10252.53UniSTS
Whitehead-RH Map10339.5UniSTS
NCBI RH Map10591.5UniSTS
RH44662  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371044,873,068 - 44,873,205UniSTSGRCh37
Build 361044,193,074 - 44,193,211RGDNCBI36
Celera1040,876,621 - 40,876,758RGD
Cytogenetic Map10q11.1UniSTS
HuRef1041,399,417 - 41,399,554UniSTS
GeneMap99-GB4 RH Map10256.28UniSTS
NCBI RH Map10591.5UniSTS
CXCL12__1181  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh371044,865,523 - 44,866,248UniSTSGRCh37
Build 361044,185,529 - 44,186,254RGDNCBI36
Celera1040,869,071 - 40,869,796RGD
HuRef1041,391,867 - 41,392,592UniSTS

miRNA Target Status

Confirmed Target Of
miRNA GeneMature miRNAMethod NameResult TypeData TypeSupport TypePMID
MIR126hsa-miR-126-3pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23396050
MIR126hsa-miR-126-3pOncomiRDBexternal_infoNANA23396050
MIR126hsa-miR-126-5pMirtarbaseexternal_infoLuciferase reporter assayFunctional MTI23396050
MIR126hsa-miR-126-5pOncomiRDBexternal_infoNANA23396050
MIR127hsa-miR-127-3pOncomiRDBexternal_infoNANA21343399
MIR222hsa-miR-222-3pOncomiRDBexternal_infoNANA21343399
MIR23Ahsa-miR-23a-3pMirtarbaseexternal_infoLuciferase reporter assay//Reporter assay;OtherFunctional MTI14697198
MIR23Ahsa-miR-23a-3pTarbaseexternal_infoReporter GenePOSITIVE
MIR23Ahsa-miR-23a-3pMirecordsexternal_infoNANA14697198
MIR223hsa-miR-223-3pOncomiRDBexternal_infoNANA21343399
MIR197hsa-miR-197-3pOncomiRDBexternal_infoNANA21343399

Predicted Target Of
Summary Value
Count of predictions:3547
Count of miRNA genes:1252
Interacting mature miRNAs:1606
Transcripts:ENST00000343575, ENST00000374426, ENST00000374429, ENST00000395793, ENST00000395794, ENST00000395795, ENST00000488591, ENST00000496375
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High 1 1 1
Medium 2005 2188 1432 536 534 375 3865 1835 950 275 894 1303 164 1 1204 2426 1 2
Low 316 306 275 79 539 78 430 331 2750 110 481 128 4 362 2
Below cutoff 16 482 2 1 634 1 12 9 23 9 23 43 3 1

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_016861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_000609 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001033886 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001178134 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001277990 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_199168 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001747171 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001747172 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001747173 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_001747174 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AI092156 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AJ227905 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK090482 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK124641 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK292628 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK311814 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL137026 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL713778 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AU120056 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AW014388 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY644456 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY802782 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY874118 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC031072 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC039893 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BX647204 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CD172464 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471160 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CR450283 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS131913 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS131917 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DA266752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ345517 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ345518 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ345519 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  DQ345520 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU037784 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EU037785 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L36033 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L36034 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U16752 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000343575   ⟹   ENSP00000339913
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1044,377,133 - 44,385,092 (-)Ensembl
RefSeq Acc Id: ENST00000374426   ⟹   ENSP00000363548
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1044,375,867 - 44,385,043 (-)Ensembl
RefSeq Acc Id: ENST00000374429   ⟹   ENSP00000363551
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1044,370,165 - 44,385,092 (-)Ensembl
RefSeq Acc Id: ENST00000395793   ⟹   ENSP00000379139
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1044,372,622 - 44,385,092 (-)Ensembl
RefSeq Acc Id: ENST00000395794   ⟹   ENSP00000379140
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1044,377,164 - 44,385,049 (-)Ensembl
RefSeq Acc Id: ENST00000395795   ⟹   ENSP00000379141
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1044,372,888 - 44,385,097 (-)Ensembl
RefSeq Acc Id: ENST00000488591
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1044,380,411 - 44,385,070 (-)Ensembl
RefSeq Acc Id: ENST00000496375
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl1044,378,557 - 44,386,493 (-)Ensembl
RefSeq Acc Id: NM_000609   ⟹   NP_000600
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381044,370,165 - 44,385,097 (-)NCBI
Build 361044,185,611 - 44,200,548 (-)NCBI Archive
HuRef1041,391,945 - 41,406,899 (-)NCBI
CHM1_11044,904,782 - 44,919,728 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001033886   ⟹   NP_001029058
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381044,375,867 - 44,385,097 (-)NCBI
GRCh371044,865,601 - 44,880,545 (-)NCBI
Build 361044,191,371 - 44,200,548 (-)NCBI Archive
HuRef1041,391,945 - 41,406,899 (-)NCBI
CHM1_11044,910,501 - 44,919,728 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001178134   ⟹   NP_001171605
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381044,377,067 - 44,385,097 (-)NCBI
GRCh371044,865,601 - 44,880,545 (-)NCBI
HuRef1041,391,945 - 41,406,899 (-)NCBI
CHM1_11044,911,696 - 44,919,728 (-)NCBI
Sequence:
RefSeq Acc Id: NM_001277990   ⟹   NP_001264919
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381044,370,165 - 44,385,097 (-)NCBI
HuRef1041,391,945 - 41,406,899 (-)NCBI
CHM1_11044,904,782 - 44,919,728 (-)NCBI
Sequence:
RefSeq Acc Id: NM_199168   ⟹   NP_954637
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381044,377,067 - 44,385,097 (-)NCBI
GRCh371044,865,601 - 44,880,545 (-)NCBI
Build 361044,192,516 - 44,200,548 (-)NCBI Archive
HuRef1041,391,945 - 41,406,899 (-)NCBI
CHM1_11044,911,696 - 44,919,728 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001747171
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381044,292,088 - 44,385,070 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001747172
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381044,292,088 - 44,385,070 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001747173
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381044,292,088 - 44,385,070 (-)NCBI
Sequence:
RefSeq Acc Id: XR_001747174
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh381044,292,088 - 44,385,070 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_000600 (Get FASTA)   NCBI Sequence Viewer  
  NP_001029058 (Get FASTA)   NCBI Sequence Viewer  
  NP_001171605 (Get FASTA)   NCBI Sequence Viewer  
  NP_001264919 (Get FASTA)   NCBI Sequence Viewer  
  NP_954637 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA97434 (Get FASTA)   NCBI Sequence Viewer  
  AAB39332 (Get FASTA)   NCBI Sequence Viewer  
  AAB39333 (Get FASTA)   NCBI Sequence Viewer  
  AAH39893 (Get FASTA)   NCBI Sequence Viewer  
  AAT76437 (Get FASTA)   NCBI Sequence Viewer  
  AAV49999 (Get FASTA)   NCBI Sequence Viewer  
  AAW82036 (Get FASTA)   NCBI Sequence Viewer  
  ABC69270 (Get FASTA)   NCBI Sequence Viewer  
  ABC69271 (Get FASTA)   NCBI Sequence Viewer  
  ABC69272 (Get FASTA)   NCBI Sequence Viewer  
  ABC69273 (Get FASTA)   NCBI Sequence Viewer  
  BAC03463 (Get FASTA)   NCBI Sequence Viewer  
  BAF85317 (Get FASTA)   NCBI Sequence Viewer  
  BAG34757 (Get FASTA)   NCBI Sequence Viewer  
  CAD28539 (Get FASTA)   NCBI Sequence Viewer  
  CAG29279 (Get FASTA)   NCBI Sequence Viewer  
  CAJ21099 (Get FASTA)   NCBI Sequence Viewer  
  CAJ21100 (Get FASTA)   NCBI Sequence Viewer  
  EAW86618 (Get FASTA)   NCBI Sequence Viewer  
  EAW86619 (Get FASTA)   NCBI Sequence Viewer  
  EAW86620 (Get FASTA)   NCBI Sequence Viewer  
  EAW86621 (Get FASTA)   NCBI Sequence Viewer  
  P48061 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_000600   ⟸   NM_000609
- Peptide Label: isoform beta precursor
- UniProtKB: P48061 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001029058   ⟸   NM_001033886
- Peptide Label: isoform gamma precursor
- UniProtKB: P48061 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001171605   ⟸   NM_001178134
- Peptide Label: isoform delta precursor
- UniProtKB: P48061 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_954637   ⟸   NM_199168
- Peptide Label: isoform alpha precursor
- UniProtKB: P48061 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_001264919   ⟸   NM_001277990
- Peptide Label: isoform 5 precursor
- UniProtKB: P48061 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: ENSP00000363548   ⟸   ENST00000374426
RefSeq Acc Id: ENSP00000363551   ⟸   ENST00000374429
RefSeq Acc Id: ENSP00000379141   ⟸   ENST00000395795
RefSeq Acc Id: ENSP00000379139   ⟸   ENST00000395793
RefSeq Acc Id: ENSP00000379140   ⟸   ENST00000395794
RefSeq Acc Id: ENSP00000339913   ⟸   ENST00000343575

Promoters
RGD ID:7217413
Promoter ID:EPDNEW_H14451
Type:initiation region
Name:CXCL12_1
Description:C-X-C motif chemokine ligand 12
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh381044,385,097 - 44,385,157EPDNEW

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
NM_199168.4(CXCL12):c.*531G>A single nucleotide variant Human immunodeficiency virus type 1, susceptibility to [RCV000009307] Chr10:44378102 [GRCh38]
Chr10:44873550 [GRCh37]
Chr10:10q11.21
pathogenic|protective
GRCh38/hg38 10q11.21-21.2(chr10:42335305-60284876)x1 copy number loss Developmental Delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052506]|Developmental delay and additional significant developmental and morphological phenotypes referred for genetic testing [RCV000052506]|See cases [RCV000052506] Chr10:42335305..60284876 [GRCh38]
Chr10:42830753..62044634 [GRCh37]
Chr10:42150759..61714640 [NCBI36]
Chr10:10q11.21-21.2
pathogenic
NM_001033886.2(CXCL12):c.291G>A (p.Gly97=) single nucleotide variant Malignant melanoma [RCV000068941] Chr10:44376008 [GRCh38]
Chr10:44871456 [GRCh37]
Chr10:44191462 [NCBI36]
Chr10:10q11.21
not provided
NM_000609.6(CXCL12):c.*2101A>G single nucleotide variant Lung cancer [RCV000109020] Chr10:44371227 [GRCh38]
Chr10:44866675 [GRCh37]
Chr10:10q11.21
uncertain significance
GRCh38/hg38 10q11.21-21.1(chr10:42884294-52265317)x3 copy number gain See cases [RCV000134381] Chr10:42884294..52265317 [GRCh38]
Chr10:43379742..54025077 [GRCh37]
Chr10:42699748..53695083 [NCBI36]
Chr10:10q11.21-21.1
pathogenic
GRCh38/hg38 10q11.21-11.23(chr10:42395201-50877059)x3 copy number gain See cases [RCV000134846] Chr10:42395201..50877059 [GRCh38]
Chr10:42890649..52636819 [GRCh37]
Chr10:42210655..52306825 [NCBI36]
Chr10:10q11.21-11.23
pathogenic
GRCh38/hg38 10q11.21-22.2(chr10:42685306-73715908)x3 copy number gain See cases [RCV000134848] Chr10:42685306..73715908 [GRCh38]
Chr10:43180754..75475666 [GRCh37]
Chr10:42500760..75145672 [NCBI36]
Chr10:10q11.21-22.2
pathogenic
GRCh38/hg38 10p15.1-q11.22(chr10:4604734-48074662)x3 copy number gain See cases [RCV000141497] Chr10:4604734..48074662 [GRCh38]
Chr10:4646926..47531169 [GRCh37]
Chr10:4636926..47125152 [NCBI36]
Chr10:10p15.1-q11.22
benign
GRCh38/hg38 10q11.21-21.3(chr10:42112187-67400675)x3 copy number gain See cases [RCV000142967] Chr10:42112187..67400675 [GRCh38]
Chr10:42607635..69160433 [GRCh37]
Chr10:41927641..68830439 [NCBI36]
Chr10:10q11.21-21.3
pathogenic
NC_000010.10:g.43611191_61663279inv inversion Pediatric metastatic thyroid tumour [RCV000585841] Chr10:43611191..61663279 [GRCh37]
Chr10:10q11.21-21.2
likely pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:93297-135378918)x3 copy number gain See cases [RCV000448750] Chr10:93297..135378918 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143) copy number gain See cases [RCV000511389] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic|uncertain significance
GRCh37/hg19 10p15.3-q26.3(chr10:100027-135427143)x3 copy number gain See cases [RCV000510861] Chr10:100027..135427143 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10p15.3-q11.23(chr10:100026-50961640)x3 copy number gain See cases [RCV000510893] Chr10:100026..50961640 [GRCh37]
Chr10:10p15.3-q11.23
pathogenic
GRCh37/hg19 10q11.21-26.3(chr10:42347406-135534747)x1 copy number loss PARP Inhibitor response [RCV000626438] Chr10:42347406..135534747 [GRCh37]
Chr10:10q11.21-26.3
drug response
NM_000609.7(CXCL12):c.266+6C>T single nucleotide variant not provided [RCV000767947] Chr10:44378631 [GRCh38]
Chr10:44874079 [GRCh37]
Chr10:10q11.21
uncertain significance
GRCh37/hg19 10q11.21(chr10:44175698-45465655)x1 copy number loss not provided [RCV000683259] Chr10:44175698..45465655 [GRCh37]
Chr10:10q11.21
uncertain significance
GRCh37/hg19 10p15.3-q26.3(chr10:73232-135524321)x3 copy number gain not provided [RCV000749464] Chr10:73232..135524321 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10p15.3-q26.3(chr10:98087-135477883)x3 copy number gain not provided [RCV000749465] Chr10:98087..135477883 [GRCh37]
Chr10:10p15.3-q26.3
pathogenic
GRCh37/hg19 10p11.21-q11.22(chr10:37149872-46169876)x3 copy number gain not provided [RCV000762700] Chr10:37149872..46169876 [GRCh37]
Chr10:10p11.21-q11.22
likely pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:10672 AgrOrtholog
COSMIC CXCL12 COSMIC
Ensembl Genes ENSG00000107562 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Protein ENSP00000339913 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000363548 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000363551 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000379139 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000379140 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000379141 UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000343575 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000374426 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000374429 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000395793 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000395794 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000395795 UniProtKB/Swiss-Prot
GTEx ENSG00000107562 GTEx
HGNC ID HGNC:10672 ENTREZGENE
Human Proteome Map CXCL12 Human Proteome Map
InterPro Chemokine_IL8-like_dom UniProtKB/Swiss-Prot
  CXC_Chemokine_domain UniProtKB/Swiss-Prot
  CXCL12 UniProtKB/Swiss-Prot
  Interleukin_8-like_sf UniProtKB/Swiss-Prot
KEGG Report hsa:6387 UniProtKB/Swiss-Prot
NCBI Gene 6387 ENTREZGENE
OMIM 600835 OMIM
  609423 OMIM
PANTHER PTHR18837 UniProtKB/Swiss-Prot
Pfam IL8 UniProtKB/Swiss-Prot
PharmGKB PA35602 PharmGKB
SMART SCY UniProtKB/Swiss-Prot
Superfamily-SCOP SSF54117 UniProtKB/Swiss-Prot
UniGene Hs.522891 ENTREZGENE
UniProt A0A024R7W4_HUMAN UniProtKB/TrEMBL
  P48061 ENTREZGENE, UniProtKB/Swiss-Prot
UniProt Secondary B2R4G0 UniProtKB/Swiss-Prot
  E7EVL0 UniProtKB/Swiss-Prot
  H7BYN8 UniProtKB/Swiss-Prot
  Q2L985 UniProtKB/Swiss-Prot
  Q2L986 UniProtKB/Swiss-Prot
  Q2L988 UniProtKB/Swiss-Prot
  Q5IT36 UniProtKB/Swiss-Prot
  Q6ICW0 UniProtKB/Swiss-Prot
  Q9H554 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2016-03-07 CXCL12  C-X-C motif chemokine ligand 12  CXCL12  chemokine (C-X-C motif) ligand 12  Symbol and/or name change 5135510 APPROVED
2011-07-27 CXCL12  chemokine (C-X-C motif) ligand 12  CXCL12  chemokine (C-X-C motif) ligand 12 (stromal cell-derived factor 1)  Symbol and/or name change 5135510 APPROVED