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Gene: GATM (glycine amidinotransferase) Homo sapiens
Symbol: GATM
Name: glycine amidinotransferase
Description: This gene encodes a mitochondrial enzyme that belongs to the amidinotransferase family. This enzyme is involved in creatine biosynthesis, whereby it catalyzes the transfer of a guanido group from L-arginine to glycine, resulting in guanidinoacetic acid, the immediate precursor of creatine. Mutations in this gene cause arginine:glycine amidinotransferase deficiency, an inborn error of creatine synthesis characterized by cognitive disability, language impairment, and behavioral disorders. [provided by RefSeq, Jul 2008]
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: AGAT; AT; CCDS3; glycine amidinotransferase (L-arginine:glycine amidinotransferase); glycine amidinotransferase, mitochondrial; L-arginine:glycine amidinotransferase; testicular secretory protein Li 19; transamidinase
Mus musculus (house mouse) : Gatm (glycine amidinotransferase (L-arginine:glycine amidinotransferase))  MGI  Alliance
Rattus norvegicus (Norway rat) : Gatm (glycine amidinotransferase)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Gatm (glycine amidinotransferase)
Pan paniscus (bonobo/pygmy chimpanzee) : GATM (glycine amidinotransferase)
Canis lupus familiaris (dog) : GATM (glycine amidinotransferase)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Gatm (glycine amidinotransferase)
Sus scrofa (pig) : GATM (glycine amidinotransferase)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh381545,361,124 - 45,402,317 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371545,653,322 - 45,670,980 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361543,440,614 - 43,458,272 (-)NCBINCBI36hg18NCBI36
Build 341543,440,613 - 43,457,998NCBI
Celera1522,544,733 - 22,562,401 (-)NCBI
Cytogenetic Map15q21.1NCBI
HuRef1522,477,507 - 22,495,086 (-)NCBIHuRef
CHM1_11545,771,808 - 45,813,500 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated
RGD Disease Portals


Comparative Map Data
Position Markers
miRNA Target Status


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
Nomenclature History
More on GATM
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 731936
Created: 2004-01-12
Species: Homo sapiens
Last Modified: 2019-06-18
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.