PPARG (peroxisome proliferator activated receptor gamma) - Rat Genome Database

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Gene: PPARG (peroxisome proliferator activated receptor gamma) Homo sapiens
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Symbol: PPARG
Name: peroxisome proliferator activated receptor gamma
RGD ID: 69168
HGNC Page HGNC
Description: Enables several functions, including R-SMAD binding activity; RNA polymerase II-specific DNA-binding transcription factor binding activity; and protein domain specific binding activity. Involved in several processes, including negative regulation of lipid storage; regulation of gene expression; and regulation of transmembrane receptor protein serine/threonine kinase signaling pathway. Acts upstream of or within negative regulation of signal transduction and regulation of gene expression. Located in RNA polymerase II transcription regulator complex and nucleoplasm. Part of receptor complex. Is active in nucleus. Implicated in several diseases, including cardiovascular system disease (multiple); end stage renal disease; lipodystrophy (multiple); obesity; and type 2 diabetes mellitus. Biomarker of coronary artery disease; hepatocellular carcinoma; and pancreatic ductal carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: CIMT1; GLM1; NR1C3; nuclear receptor subfamily 1 group C member 3; peroxisome proliferator activated receptor, gamma; peroxisome proliferator-activated nuclear receptor gamma variant 1; peroxisome proliferator-activated receptor gamma; peroxisome proliferator-activated receptor gamma 1; peroxisome proliferator-activated receptor-gamma 5; peroxisome proliferator-activated receptor-gamma splicing; PPAR gamma; PPAR-gamma; PPARG1; PPARG2; PPARG5; PPARgamma
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38312,287,368 - 12,434,344 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl312,287,368 - 12,434,356 (+)EnsemblGRCh38hg38GRCh38
GRCh37312,328,867 - 12,475,843 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36312,304,349 - 12,450,855 (+)NCBINCBI36hg18NCBI36
Build 34312,304,423 - 12,450,840NCBI
Celera312,266,744 - 12,413,226 (+)NCBI
Cytogenetic Map3p25.2NCBI
HuRef312,263,090 - 12,409,169 (+)NCBIHuRef
CHM1_1312,279,448 - 12,425,942 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model