GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PPARG | multiple interactions | EXP | | 6480464 | CTD | Clofibrate results in increased activity of [PPARG protein alternative form binds to RXRA protein] | PMID:11779144 | PPARG | affects response to substance | ISO | Pparg (Rattus norvegicus) | 6480464 | CTD | PPARG protein affects the susceptibility to Clofibrate | PMID:12604186 | PPARG | increases expression | ISO | Pparg (Rattus norvegicus) | 6480464 | CTD | Clofibrate results in increased expression of PPARG mRNA; Clofibrate results in increased expression of PPARG protein | PMID:12604186 PMID:12699904 | PPARG | increases response to substance | ISO | Pparg (Rattus norvegicus) | 6480464 | CTD | PPARG results in increased susceptibility to Clofibrate | PMID:12699904 | PPARG | multiple interactions | ISO | Pparg (Rattus norvegicus) | 6480464 | CTD | PPARG protein promotes the reaction [Clofibrate results in decreased expression of ALDH3A1 mRNA] | PMID:12604186 | PPARG | multiple interactions | ISO | Pparg (Mus musculus) | 6480464 | CTD | [Clofibrate co-treated with PPARG] results in increased expression of FABP4 mRNA; [Clofibrate co-treated with PPARG] results in increased expression of RORA mRNA; [Clofibrate co-treated with PPARG] results in increased expression of RORC mRNA | PMID:9543393 | | ||||||||||||||||||||||
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