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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69168
Species: Homo sapiens
RGD Object: Gene
Symbol: PPARG
Name: peroxisome proliferator activated receptor gamma
Acc ID: CHEBI:8434
Term: prochloraz
Definition: A member of the class of ureas that is 1H-imidazole-1-carboxamide substituted by a propyl and a 2-(2,4,6-trichlorophenoxy)ethyl group at the amino nitrogen atom. A fungicide active against a wide range of diseases affecting field crops, fruit, turf and vegetables.
Chemical ID: MESH:C045362
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PPARGdecreases expressionEXP 6480464CTDprochloraz results in decreased expression of PPARG mRNAPMID:30879083
PPARGmultiple interactionsEXP 6480464CTDprochloraz binds to and results in increased activity of PPARG proteinPMID:33049310
PPARGmultiple interactionsISOPparg (Mus musculus)6480464CTDprochloraz binds to and results in increased activity of PPARG proteinPMID:33049310
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