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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69168
Species: Homo sapiens
RGD Object: Gene
Symbol: PPARG
Name: peroxisome proliferator activated receptor gamma
Acc ID: CHEBI:41977
Term: daunorubicin
Definition: A natural product found in Actinomadura roseola.
Chemical ID: MESH:D003630
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PPARGdecreases activityEXP 6480464CTDDaunorubicin results in decreased activity of PPARG proteinPMID:25257666
PPARGincreases expressionISOPparg (Rattus norvegicus)6480464CTDDaunorubicin results in increased expression of PPARG proteinPMID:20888384
PPARGmultiple interactionsISOPparg (Rattus norvegicus)6480464CTDtelmisartan promotes the reaction [Daunorubicin results in increased expression of PPARG protein]PMID:20888384
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