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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69168
Species: Homo sapiens
RGD Object: Gene
Symbol: PPARG
Name: peroxisome proliferator activated receptor gamma
Acc ID: CHEBI:3374
Term: capsaicin
Definition: A capsaicinoid that has formula C18H27NO3.
Chemical ID: MESH:D002211
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PPARGdecreases expressionEXP 6480464CTDCapsaicin results in decreased expression of PPARG mRNAPMID:18769453
PPARGincreases activityEXP 6480464CTDCapsaicin results in increased activity of PPARG proteinPMID:15383218
PPARGmultiple interactionsEXP 6480464CTD2,2-bis(4-glycidyloxyphenyl)propane inhibits the reaction [Capsaicin results in increased activity of PPARG protein]PMID:15383218
PPARGdecreases expressionISOPparg (Mus musculus)6480464CTDCapsaicin results in decreased expression of PPARG proteinPMID:17295509
PPARGmultiple interactionsISOPparg (Rattus norvegicus)6480464CTDCapsaicin inhibits the reaction [Dietary Fats results in decreased expression of PPARG mRNA]PMID:20359164
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