GWAS763978_H QTL Report (Homo sapiens) - Rat Genome Database

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QTL Registration

QTL: GWAS763978_H (body fat percentage QTL GWAS763978 (human)) Homo sapiens

Symbol: GWAS763978_H
Name: body fat percentage QTL GWAS763978 (human)
RGD ID: 407115002
Trait: body fat percentage
Measurement Type: body fat percentage   (CMO:0000302)    
LOD Score: Not Available
P Value: 4.0E-17
Variance: Not Available
Position
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh38312,303,231 - 12,303,232RGD_MAPPER_PIPELINEGRCh38
GRCh37312,344,730 - 12,344,731RGD_MAPPER_PIPELINEGRCh37
Population Stats: Not Available
JBrowse: View Region in Genome Browser (JBrowse)
Model



Experimental Data Annotations    Click to see Annotation Detail View

Clinical Measurement
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS763978_HHumanbody fat percentage  IAGPrs11712037405850206Based on the EFO term IDGWAS_CATALOGPMID:30593698

Experimental Factor Annotations    Click to see Annotation Detail View
Object SymbolSpeciesTermQualifierEvidenceWithReferenceNotesSourceOriginal Reference(s)
GWAS763978_HHumanbody fat percentage  IAGPrs11712037405850206 GWAS_CATALOGPMID:30593698
Experimental Data Annotations     Click to see Annotation Detail View

Clinical Measurement

References

References - curated
# Reference Title Reference Citation
1. RGD GWAS Catalog Import Pipeline RGD pipeline to import data from GWAS Catalog and create human variant and QTL records

Region

Genes in Region
The following Genes overlap with this region.    Full Report CSV TAB Printer Analysis Tools
RGD IDSymbolNameChrStartStopSpecies
69168PPARGperoxisome proliferator activated receptor gamma31228736812434344Human

Position Markers

Peak: (rs11712037)
Human AssemblyChrPosition (strand)Source
GRCh38312,303,231 - 12,303,232RGD_MAPPER_PIPELINE


QTLs in Region (GRCh38)
The following QTLs overlap with this region.    Full Report CSV TAB Printer Gviewer
RGD IDSymbolNameLODP ValueTraitSub TraitChrStartStopSpecies
407207265GWAS856241_Hinsulin measurement QTL GWAS856241 (human)2e-21insulin measurementpancreatic islet insulin release measurement (CMO:0001216)31230323112303232Human
407095163GWAS744139_Hbody fat percentage QTL GWAS744139 (human)3e-10body fat percentagebody fat percentage (CMO:0000302)31230323112303232Human
407094874GWAS743850_Hbody fat percentage QTL GWAS743850 (human)1e-08body fat percentagebody fat percentage (CMO:0000302)31230323112303232Human
2316345GLUCO224_HGlucose level QTL 224 (human)1.270.008Glucose level3121543441Human
407167342GWAS816318_Haspartate aminotransferase measurement QTL GWAS816318 (human)2e-16aspartate aminotransferase measurementblood aspartate aminotransferase activity level (CMO:0000580)31230323112303232Human
406922045GWAS571021_HDrugs used in diabetes use measurement QTL GWAS571021 (human)3e-20Drugs used in diabetes use measurement31230323112303232Human
407115002GWAS763978_Hbody fat percentage QTL GWAS763978 (human)4e-17body fat percentagebody fat percentage (CMO:0000302)31230323112303232Human
407169819GWAS818795_Hserum alanine aminotransferase measurement QTL GWAS818795 (human)2e-41serum alanine aminotransferase measurementserum alanine aminotransferase activity level (CMO:0000575)31230323112303232Human


Additional Information

GWAS QTLs Related by Peak Marker
Data has come from the GWAS Catalog   
The highlighted row represents the current QTL
QTL GWAS Catalog Study Disease Trait Study Size Risk Allele Risk Allele Frequency P Value P Value MLOG Peak Marker Reported Odds Ratio or Beta-coefficient Ontology Accession PubMed
GWAS571021_H GCST90250911 Medication use for T2D (number of purchases) 567,671 European ancestry individuals ? NR 3E-20 19.523 rs11712037 0.012258 Drugs used in diabetes use measurement (EFO:0009924)
 PMID:36653479
GWAS743850_H GCST007064 Body fat percentage 70,700 European ancestry female individuals, 85,261 European ancestry male individuals ? NR 1E-8 8 rs11712037 0.30271 body fat percentage (EFO:0007800)
 PMID:30593698
GWAS744139_H GCST007064 Body fat percentage 70,700 European ancestry female individuals, 85,261 European ancestry male individuals ? NR 3E-10 9.523 rs11712037 0.25189 body fat percentage (EFO:0007800)
 PMID:30593698
GWAS763978_H GCST007064 Body fat percentage 70,700 European ancestry female individuals, 85,261 European ancestry male individuals ? NR 4E-17 16.398 rs11712037 0.27358 body fat percentage (EFO:0007800)
 PMID:30593698
GWAS816318_H GCST90013664 Aspartate aminotransferase levels 386,570 British ancestry individuals, 10,617 Asian or Asian British individuals, 7,426 Black or Black British individuals, 2,321 Chinese ancestry individuals ? NR 2E-16 15.699 rs11712037 0.0034 aspartate aminotransferase measurement (EFO:0004736)
 PMID:34315874
GWAS818795_H GCST90013663 Alanine aminotransferase levels 387,859 British ancestry individuals, 10,635 Asian or Asian British individuals, 7,468 Black or Black British individuals, 2,338 Chinese ancestry individuals ? NR 2E-41 40.699 rs11712037 0.0086 serum alanine aminotransferase measurement (EFO:0004735)
 PMID:34315874
GWAS856241_H GCST90002238 Fasting insulin 151,013 European ancestry individuals C 0.8653 2E-21 20.699 rs11712037 0.0278 insulin measurement (EFO:0004467)
 PMID:34059833
Database Acc Id Source(s)
GWAS Catalog GCST007064 GWAS Catalog

RGD Curation Notes
Note Type Note Reference