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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69168
Species: Homo sapiens
RGD Object: Gene
Symbol: PPARG
Name: peroxisome proliferator activated receptor gamma
Acc ID: CHEBI:6775
Term: mesalamine
Definition: A monohydroxybenzoic acid that is salicylic acid substituted by an amino group at the 5-position.
Chemical ID: MESH:D019804
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PPARGmultiple interactionsEXP 6480464CTD[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with Mesalamine] results in increased expression of PPARG protein; Mesalamine inhibits the reaction [[IL1A protein co-treated with TNF protein co-treated with IFNG protein co-treated with cyanidin-3-O-beta-glucopyranoside] results in increased expression of PPARG protein]PMID:27818126
PPARGmultiple interactionsISOPparg (Mus musculus)6480464CTDMesalamine inhibits the reaction [Dextran Sulfate affects the localization of PPARG protein]PMID:33130971
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