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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69168
Species: Homo sapiens
RGD Object: Gene
Symbol: PPARG
Name: peroxisome proliferator activated receptor gamma
Acc ID: CHEBI:35696
Term: cobalt dichloride
Definition: A cobalt salt in which the cobalt metal is in the +2 oxidation state and the counter-anion is chloride. It is used as an indicator for water in desiccants.
Chemical ID: MESH:C018021
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PPARGdecreases expressionEXP 6480464CTDcobaltous chloride results in decreased expression of PPARG mRNAPMID:15708366
PPARGdecreases expressionISOPparg (Mus musculus)6480464CTDcobaltous chloride results in decreased expression of PPARG mRNAPMID:20594416
PPARGmultiple interactionsISOPparg (Mus musculus)6480464CTD2,2-bis(4-glycidyloxyphenyl)propane affects the reaction [[cobaltous chloride co-treated with Phloretin] affects the expression of PPARG mRNA]; [cobaltous chloride co-treated with lipopolysaccharide, E coli O55-B5 co-treated with Phloretin] results in increased expression of PPARG mRNA; [cobaltous chloride co-treated with Phloretin] affects the expression of PPARG mRNAPMID:32408695
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