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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69168
Species: Homo sapiens
RGD Object: Gene
Symbol: PPARG
Name: peroxisome proliferator activated receptor gamma
Acc ID: CHEBI:27363
Term: zinc atom
Definition: A zinc group element atom that has formula Zn.
Chemical ID: MESH:D015032
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PPARGmultiple interactionsEXP 6480464CTD[PCI 5002 co-treated with Zinc] results in increased expression of PPARG mRNAPMID:18593933
PPARGdecreases expressionISOPparg (Rattus norvegicus)6480464CTDZinc deficiency results in decreased expression of PPARG mRNAPMID:20128680
PPARGmultiple interactionsISOPparg (Mus musculus)6480464CTD[LDLR gene mutant form results in increased susceptibility to Zinc deficiency] which results in increased expression of PPARG mRNAPMID:16140885
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