EPHX1 Human (1->4)-beta-D-glucan multiple interactions ISO Ephx1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Cellulose] results in increased expression of EPHX1 mRNA CTD PMID:36331819 EPHX1 Human (2,4,5-trichlorophenoxy)acetic acid increases activity ISO Ephx1 (Mus musculus) 6480464 2 more ... CTD PMID:3032197 EPHX1 Human (9R,10S)-9,10-epoxy-9,10-dihydrophenanthrene increases metabolic processing ISO Ephx1 (Mus musculus) 6480464 EPHX1 protein mutant form results in increased metabolism of 9 more ... CTD PMID:26838043 EPHX1 Human (S)-mandelic acid multiple interactions EXP 6480464 EPHX1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 EPHX1 Human 1,1,1-Trichloro-2-(o-chlorophenyl)-2-(p-chlorophenyl)ethane affects expression ISO Ephx1 (Rattus norvegicus) 6480464 o and p'-DDT affects the expression of EPHX1 mRNA CTD PMID:17984292 EPHX1 Human 1,1-dichloroethene increases expression ISO Ephx1 (Mus musculus) 6480464 vinylidene chloride results in increased expression of EPHX1 mRNA CTD PMID:26682919 EPHX1 Human 1,2-dibromoethane decreases expression ISO Ephx1 (Mus musculus) 6480464 Ethylene Dibromide results in decreased expression of EPHX1 mRNA CTD PMID:17311802 EPHX1 Human 1,2-dihydronaphthalene-1,2-diol multiple interactions ISO Ephx1 (Mus musculus) 6480464 [EPHX1 protein results in increased metabolism of naphthalene] which results in increased chemical synthesis of 1 more ... CTD PMID:18363382 and PMID:26840748 EPHX1 Human 1,2-dimethylhydrazine increases expression ISO Ephx1 (Mus musculus) 6480464 1 and 2-Dimethylhydrazine results in increased expression of EPHX1 mRNA CTD PMID:22206623 EPHX1 Human 1,3,5-trimethylbenzene increases expression EXP 6480464 mesitylene results in increased expression of EPHX1 mRNA CTD PMID:33269480 EPHX1 Human 1,4-dioxane increases expression ISO Ephx1 (Mus musculus) 6480464 1 and 4-dioxane results in increased expression of EPHX1 mRNA CTD PMID:33693819 EPHX1 Human 1-benzofuran increases expression ISO Ephx1 (Mus musculus) 6480464 benzofuran results in increased expression of EPHX1 mRNA CTD PMID:17311802 EPHX1 Human 1-benzofuran affects expression ISO Ephx1 (Mus musculus) 6480464 benzofuran affects the expression of EPHX1 mRNA CTD PMID:17114358 EPHX1 Human 1-naphthyl isothiocyanate increases expression ISO Ephx1 (Rattus norvegicus) 6480464 1-Naphthylisothiocyanate results in increased expression of EPHX1 mRNA CTD PMID:30723492 EPHX1 Human 1-nitropropane decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 1-nitropropane results in decreased expression of EPHX1 mRNA CTD PMID:17070881 EPHX1 Human 17alpha-ethynylestradiol affects expression ISO Ephx1 (Mus musculus) 6480464 Ethinyl Estradiol affects the expression of EPHX1 mRNA CTD PMID:17555576 EPHX1 Human 17alpha-ethynylestradiol increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Ethinyl Estradiol results in increased expression of EPHX1 mRNA CTD PMID:16926038 EPHX1 Human 17alpha-ethynylestradiol decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 Ethinyl Estradiol results in decreased expression of EPHX1 mRNA CTD PMID:16174780 and PMID:29097150 EPHX1 Human 17alpha-ethynylestradiol multiple interactions ISO Ephx1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in decreased expression of EPHX1 mRNA CTD PMID:17942748 EPHX1 Human 17alpha-ethynylestradiol decreases expression ISO Ephx1 (Mus musculus) 6480464 Ethinyl Estradiol results in decreased expression of EPHX1 mRNA CTD PMID:16174780 EPHX1 Human 17alpha-ethynylestradiol increases expression ISO Ephx1 (Mus musculus) 6480464 Ethinyl Estradiol results in increased expression of EPHX1 mRNA CTD PMID:17942748 EPHX1 Human 17beta-estradiol affects expression EXP 6480464 Estradiol affects the expression of EPHX1 mRNA CTD PMID:14699072 EPHX1 Human 17beta-estradiol increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Estradiol results in increased expression of EPHX1 protein CTD PMID:32145629 EPHX1 Human 17beta-estradiol multiple interactions EXP 6480464 [Estradiol co-treated with TGFB1 protein] results in decreased expression of EPHX1 mRNA CTD PMID:30165855 EPHX1 Human 17beta-estradiol multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [bisphenol A co-treated with Estradiol] results in decreased expression of EPHX1 mRNA CTD PMID:26496021 EPHX1 Human 17beta-estradiol 3-benzoate decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 estradiol 3-benzoate results in decreased expression of EPHX1 protein CTD PMID:24752506 EPHX1 Human 1H-pyrazole increases expression ISO Ephx1 (Mus musculus) 6480464 pyrazole results in increased expression of EPHX1 mRNA CTD PMID:17945193 EPHX1 Human 2,2',4,4',5,5'-hexachlorobiphenyl increases activity ISO Ephx1 (Rattus norvegicus) 6480464 2 more ... CTD PMID:1372805 EPHX1 Human 2,2',4,4',5,5'-hexachlorobiphenyl multiple interactions ISO Ephx1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 EPHX1 Human 2,2',4,4'-Tetrabromodiphenyl ether increases expression ISO Ephx1 (Rattus norvegicus) 6480464 2 more ... CTD PMID:31826744 and PMID:32679240 EPHX1 Human 2,2,2-tetramine multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 Trientine inhibits the reaction [Streptozocin results in increased expression of EPHX1 protein] CTD PMID:19634143 EPHX1 Human 2,2-Bis(bromomethyl)propane-1,3-diol increases expression ISO Ephx1 (Mus musculus) 6480464 2 more ... CTD PMID:17311802 EPHX1 Human 2,3,7,8-tetrachlorodibenzodioxine multiple interactions ISO Ephx1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:17942748 more ... EPHX1 Human 2,3,7,8-tetrachlorodibenzodioxine decreases expression ISO Ephx1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in decreased expression of EPHX1 mRNA CTD PMID:33956508 EPHX1 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Ephx1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin results in increased expression of EPHX1 mRNA and Tetrachlorodibenzodioxin results in increased expression of EPHX1 protein CTD PMID:15328365 more ... EPHX1 Human 2,3,7,8-tetrachlorodibenzodioxine affects expression ISO Ephx1 (Mus musculus) 6480464 Tetrachlorodibenzodioxin affects the expression of EPHX1 mRNA CTD PMID:20702594 and PMID:21570461 EPHX1 Human 2,3,7,8-tetrachlorodibenzodioxine increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Tetrachlorodibenzodioxin results in increased expression of EPHX1 mRNA CTD PMID:16960034 more ... EPHX1 Human 2,3,7,8-Tetrachlorodibenzofuran affects expression ISO Ephx1 (Mus musculus) 6480464 2 more ... CTD PMID:20702594 EPHX1 Human 2,3-dimethoxynaphthalene-1,4-dione decreases expression EXP 6480464 2 more ... CTD PMID:17547211 EPHX1 Human 2,4,6-tribromophenol increases expression EXP 6480464 2 more ... CTD PMID:31675489 EPHX1 Human 2,4,6-trinitrotoluene affects expression ISO Ephx1 (Rattus norvegicus) 6480464 Trinitrotoluene affects the expression of EPHX1 mRNA CTD PMID:21346803 EPHX1 Human 2,4-D increases activity ISO Ephx1 (Mus musculus) 6480464 2 and 4-Dichlorophenoxyacetic Acid results in increased activity of EPHX1 protein CTD PMID:3032197 EPHX1 Human 2,4-diaminotoluene increases expression ISO Ephx1 (Rattus norvegicus) 6480464 2 and 4-diaminotoluene results in increased expression of EPHX1 mRNA CTD PMID:17070881 EPHX1 Human 2,4-dibromophenyl 2,4,5-tribromophenyl ether affects expression ISO Ephx1 (Mus musculus) 6480464 2 more ... CTD PMID:38648751 EPHX1 Human 2,4-dinitrotoluene increases activity ISO Ephx1 (Mus musculus) 6480464 2 and 4-dinitrotoluene results in increased activity of EPHX1 protein CTD PMID:3621371 EPHX1 Human 2,4-dinitrotoluene affects expression ISO Ephx1 (Rattus norvegicus) 6480464 2 and 4-dinitrotoluene affects the expression of EPHX1 mRNA CTD PMID:21346803 EPHX1 Human 2,6-diaminotoluene decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 2 and 6-diaminotoluene results in decreased expression of EPHX1 mRNA CTD PMID:17070881 EPHX1 Human 2,6-dinitrotoluene affects expression ISO Ephx1 (Rattus norvegicus) 6480464 2 and 6-dinitrotoluene affects the expression of EPHX1 mRNA CTD PMID:21346803 EPHX1 Human 2,8-bis-Trifluoromethyl-4-quinoline carboxylic acid increases expression EXP 6480464 Ro 21-5104 results in increased expression of EPHX1 mRNA CTD PMID:25313206 EPHX1 Human 2-acetamidofluorene increases expression ISO Ephx1 (Rattus norvegicus) 6480464 2-Acetylaminofluorene results in increased expression of EPHX1 mRNA CTD PMID:17070881 EPHX1 Human 2-acetamidofluorene increases expression ISO Ephx1 (Mus musculus) 6480464 2-Acetylaminofluorene results in increased expression of EPHX1 mRNA CTD PMID:17317680 and PMID:21607683 EPHX1 Human 2-nitro-p-phenylenediamine increases expression ISO Ephx1 (Rattus norvegicus) 6480464 2-nitro-4-phenylenediamine results in increased expression of EPHX1 mRNA CTD PMID:17070881 EPHX1 Human 2-nitrofluorene increases expression ISO Ephx1 (Rattus norvegicus) 6480464 2-nitrofluorene results in increased expression of EPHX1 mRNA CTD PMID:14600272 more ... EPHX1 Human 2-nitropropane increases expression ISO Ephx1 (Rattus norvegicus) 6480464 2-nitropropane results in increased expression of EPHX1 mRNA CTD PMID:17070881 EPHX1 Human 2-Oxohexane increases activity ISO Ephx1 (Rattus norvegicus) 6480464 Methyl n-Butyl Ketone results in increased activity of EPHX1 protein CTD PMID:1372805 EPHX1 Human 2-tert-butylhydroquinone increases expression ISO Ephx1 (Rattus norvegicus) 6480464 2-tert-butylhydroquinone results in increased expression of EPHX1 mRNA CTD PMID:20650352 EPHX1 Human 2-tert-butylhydroquinone multiple interactions EXP 6480464 NFE2L2 mutant form inhibits the reaction [2-tert-butylhydroquinone results in increased expression of EPHX1 exon] CTD PMID:24704207 EPHX1 Human 2-tert-butylhydroquinone increases expression EXP 6480464 2-tert-butylhydroquinone results in increased expression of EPHX1 exon and 2-tert-butylhydroquinone results in increased expression of EPHX1 protein alternative form CTD PMID:24704207 EPHX1 Human 3,3',4,4',5-pentachlorobiphenyl increases expression ISO Ephx1 (Rattus norvegicus) 6480464 3 more ... CTD PMID:20959002 EPHX1 Human 3,3',4,4',5-pentachlorobiphenyl increases expression ISO Ephx1 (Mus musculus) 6480464 3 more ... CTD PMID:23994337 EPHX1 Human 3,4-dihydrocoumarin decreases expression ISO Ephx1 (Mus musculus) 6480464 3 and 4-dihydrocoumarin results in decreased expression of EPHX1 mRNA CTD PMID:22016648 EPHX1 Human 3-chloropropane-1,2-diol increases expression ISO Ephx1 (Rattus norvegicus) 6480464 alpha-Chlorohydrin results in increased expression of EPHX1 mRNA and alpha-Chlorohydrin results in increased expression of EPHX1 protein CTD PMID:28522335 and PMID:34915118 EPHX1 Human 3-isobutyl-1-methyl-7H-xanthine multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of EPHX1 mRNA more ... CTD PMID:28628672 EPHX1 Human 3-methylcholanthrene increases activity ISO Ephx1 (Mus musculus) 6480464 Methylcholanthrene results in increased activity of EPHX1 protein CTD PMID:3621371 EPHX1 Human 3-methylcholanthrene increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Methylcholanthrene results in increased expression of EPHX1 mRNA CTD PMID:23273579 EPHX1 Human 3H-1,2-dithiole-3-thione increases expression ISO Ephx1 (Rattus norvegicus) 6480464 1 and 2-dithiol-3-thione results in increased expression of EPHX1 mRNA CTD PMID:19162173 and PMID:19695238 EPHX1 Human 4,4'-sulfonyldiphenol multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol S] results in increased expression of EPHX1 mRNA CTD PMID:28628672 EPHX1 Human 4,4'-sulfonyldiphenol multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of EPHX1 mRNA CTD PMID:36041667 EPHX1 Human 4,4'-sulfonyldiphenol decreases expression ISO Ephx1 (Mus musculus) 6480464 bisphenol S results in decreased expression of EPHX1 mRNA CTD PMID:30951980 EPHX1 Human 4-(N-nitrosomethylamino)-1-(3-pyridyl)butan-1-one increases expression ISO Ephx1 (Rattus norvegicus) 6480464 4-(N-methyl-N-nitrosamino)-1-(3-pyridyl)-1-butanone results in increased expression of EPHX1 mRNA CTD PMID:14600272 more ... EPHX1 Human 4-acetylaminofluorene increases expression ISO Ephx1 (Rattus norvegicus) 6480464 4-acetylaminofluorene results in increased expression of EPHX1 mRNA CTD PMID:17070881 EPHX1 Human 4-amino-2,6-dinitrotoluene affects expression ISO Ephx1 (Rattus norvegicus) 6480464 4-amino-2 and 6-dinitrotoluene affects the expression of EPHX1 mRNA CTD PMID:21346803 EPHX1 Human 4-hydroxynon-2-enal increases expression ISO Ephx1 (Mus musculus) 6480464 4-hydroxy-2-nonenal results in increased expression of EPHX1 mRNA CTD PMID:19191707 EPHX1 Human 4-hydroxyphenyl retinamide increases expression ISO Ephx1 (Mus musculus) 6480464 Fenretinide results in increased expression of EPHX1 mRNA CTD PMID:28973697 EPHX1 Human 4-nitro-1,2-phenylenediamine increases expression ISO Ephx1 (Rattus norvegicus) 6480464 1 and 2-diamino-4-nitrobenzene results in increased expression of EPHX1 mRNA CTD PMID:17070881 EPHX1 Human 4-vinylcyclohexene dioxide decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 4-vinyl-1-cyclohexene dioxide results in decreased expression of EPHX1 mRNA CTD PMID:8806858 EPHX1 Human 4-vinylcyclohexene dioxide multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [cyclohexene oxide results in decreased activity of EPHX1 protein] which results in increased susceptibility to 4-vinyl-1-cyclohexene dioxide CTD PMID:22061827 EPHX1 Human 4-vinylcyclohexene dioxide increases metabolic processing ISO Ephx1 (Rattus norvegicus) 6480464 EPHX1 protein results in increased metabolism of 4-vinyl-1-cyclohexene dioxide CTD PMID:22061827 EPHX1 Human 4-vinylcyclohexene dioxide increases expression ISO Ephx1 (Mus musculus) 6480464 4-vinyl-1-cyclohexene dioxide results in increased expression of EPHX1 mRNA and 4-vinyl-1-cyclohexene dioxide results in increased expression of EPHX1 protein CTD PMID:22061827 EPHX1 Human 4-vinylcyclohexene dioxide increases expression ISO Ephx1 (Rattus norvegicus) 6480464 4-vinyl-1-cyclohexene dioxide results in increased expression of EPHX1 mRNA and 4-vinyl-1-cyclohexene dioxide results in increased expression of EPHX1 protein CTD PMID:22061827 and PMID:8806858 EPHX1 Human 4-vinylcyclohexene dioxide increases metabolic processing ISO Ephx1 (Mus musculus) 6480464 EPHX1 protein results in increased metabolism of 4-vinyl-1-cyclohexene dioxide CTD PMID:22061827 EPHX1 Human 5,6alpha-epoxy-5alpha-cholestan-3beta-ol increases metabolic processing ISO Ephx1 (Mus musculus) 6480464 EPHX1 protein results in increased metabolism of cholesterol alpha-oxide CTD PMID:2043152 EPHX1 Human 5,6alpha-epoxy-5alpha-cholestan-3beta-ol multiple interactions ISO Ephx1 (Mus musculus) 6480464 disparlure promotes the reaction [EPHX1 protein results in increased metabolism of cholesterol alpha-oxide] and Lanosterol analog inhibits the reaction [EPHX1 protein results in increased metabolism of cholesterol alpha-oxide] CTD PMID:2043152 EPHX1 Human 5-aza-2'-deoxycytidine increases expression EXP 6480464 Decitabine results in increased expression of EPHX1 mRNA CTD PMID:19194470 EPHX1 Human 5-fluorouracil affects response to substance EXP 6480464 EPHX1 protein affects the susceptibility to Fluorouracil CTD PMID:16217747 EPHX1 Human 5-fluorouracil increases expression EXP 6480464 Fluorouracil results in increased expression of EPHX1 mRNA CTD PMID:15205334 EPHX1 Human 7,12-dimethyltetraphene multiple interactions EXP 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of 9 more ... CTD PMID:8961944 EPHX1 Human 7,12-dimethyltetraphene increases expression ISO Ephx1 (Rattus norvegicus) 6480464 9 more ... CTD PMID:19027032 and PMID:24576726 EPHX1 Human 7,12-dimethyltetraphene decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 9 more ... CTD PMID:12376462 EPHX1 Human 7,12-dimethyltetraphene affects response to substance ISO Ephx1 (Mus musculus) 6480464 EPHX1 protein affects the susceptibility to 9 more ... CTD PMID:15331171 and PMID:17442664 EPHX1 Human 7,12-dimethyltetraphene increases expression ISO Ephx1 (Mus musculus) 6480464 9 more ... CTD PMID:17204581 and PMID:19027032 EPHX1 Human 7,12-dimethyltetraphene increases response to substance ISO Ephx1 (Mus musculus) 6480464 EPHX1 protein results in increased susceptibility to 9 more ... CTD PMID:11323178 and PMID:19027032 EPHX1 Human 7,12-dimethyltetraphene multiple interactions ISO Ephx1 (Mus musculus) 6480464 [cyclohexene oxide results in decreased activity of EPHX1 protein] which results in decreased susceptibility to 9 more ... CTD PMID:17204581 more ... EPHX1 Human 8,9-EET affects hydrolysis ISO Ephx1 (Mus musculus) 6480464 EPHX1 protein affects the hydrolysis of 8 and 9-epoxyeicosatrienoic acid CTD PMID:28975360 EPHX1 Human 8-Br-cAMP increases expression EXP 6480464 8-Bromo Cyclic Adenosine Monophosphate results in increased expression of EPHX1 mRNA CTD PMID:22079614 EPHX1 Human 9,10-epoxy-9,10-dihydrophenanthrene increases metabolic processing ISO Ephx1 (Mus musculus) 6480464 EPHX1 protein mutant form results in increased metabolism of 9 more ... CTD PMID:26838043 EPHX1 Human acetamide increases expression ISO Ephx1 (Rattus norvegicus) 6480464 acetamide results in increased expression of EPHX1 mRNA CTD PMID:31881176 EPHX1 Human acrylamide multiple interactions EXP 6480464 [EPHX1 gene polymorphism affects the metabolism of Acrylamide] which affects the chemical synthesis of glycidamide analog CTD PMID:21402133 EPHX1 Human acrylamide increases expression EXP 6480464 Acrylamide results in increased expression of EPHX1 mRNA CTD PMID:32763439 EPHX1 Human acrylamide affects metabolic processing EXP 6480464 EPHX1 gene polymorphism affects the metabolism of Acrylamide CTD PMID:21402133 EPHX1 Human actinomycin D multiple interactions EXP 6480464 [Dactinomycin co-treated with nutlin 3] results in increased secretion of EPHX1 protein CTD PMID:38460933 EPHX1 Human aflatoxin B1 increases response to substance EXP 6480464 EPHX1 gene mutant form results in increased susceptibility to Aflatoxin B1 CTD PMID:7892276 EPHX1 Human aflatoxin B1 increases activity ISO Ephx1 (Rattus norvegicus) 152998935 aflatoxin increases Ephx1 enzyme activity in rat liver microsomes RGD EPHX1 Human aflatoxin B1 decreases methylation EXP 6480464 Aflatoxin B1 results in decreased methylation of EPHX1 gene CTD PMID:27153756 EPHX1 Human aflatoxin B1 decreases expression EXP 6480464 Aflatoxin B1 results in decreased expression of EPHX1 mRNA CTD PMID:27153756 EPHX1 Human aflatoxin B1 increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Aflatoxin B1 results in increased expression of EPHX1 mRNA CTD PMID:14600272 more ... EPHX1 Human aflatoxin B1 affects response to substance ISO Ephx1 (Mus musculus) 6480464 EPHX1 gene SNP affects the susceptibility to Aflatoxin B1 CTD PMID:12907637 EPHX1 Human all-trans-retinoic acid multiple interactions ISO Ephx1 (Mus musculus) 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of EPHX1 mRNA CTD PMID:30951980 EPHX1 Human all-trans-retinoic acid decreases expression EXP 6480464 Tretinoin results in decreased expression of EPHX1 mRNA CTD PMID:33167477 EPHX1 Human alpha-hexachlorocyclohexane increases expression ISO Ephx1 (Rattus norvegicus) 6480464 alpha-hexachlorocyclohexane results in increased expression of EPHX1 mRNA CTD PMID:16940010 EPHX1 Human alpha-hexachlorocyclohexane increases activity ISO Ephx1 (Rattus norvegicus) 6480464 alpha-hexachlorocyclohexane results in increased activity of EPHX1 protein CTD PMID:1372805 EPHX1 Human amiodarone affects expression ISO Ephx1 (Rattus norvegicus) 6480464 Amiodarone affects the expression of EPHX1 mRNA CTD PMID:18355885 EPHX1 Human amitriptyline affects expression ISO Ephx1 (Rattus norvegicus) 6480464 Amitriptyline affects the expression of EPHX1 mRNA CTD PMID:18355885 EPHX1 Human ammonium chloride affects expression ISO Ephx1 (Rattus norvegicus) 6480464 Ammonium Chloride affects the expression of EPHX1 mRNA CTD PMID:16483693 EPHX1 Human aniline increases expression ISO Ephx1 (Mus musculus) 6480464 aniline results in increased expression of EPHX1 mRNA CTD PMID:22016648 EPHX1 Human antimonite multiple interactions EXP 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of EPHX1 mRNA CTD PMID:32076005 EPHX1 Human aristolochic acid A increases expression ISO Ephx1 (Rattus norvegicus) 6480464 aristolochic acid I results in increased expression of EPHX1 mRNA CTD PMID:17483316 EPHX1 Human aristolochic acid A increases expression EXP 6480464 aristolochic acid I results in increased expression of EPHX1 mRNA CTD PMID:33212167 EPHX1 Human aristolochic acid A multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [aristolochic acid I co-treated with aristolochic acid II] results in increased expression of EPHX1 mRNA CTD PMID:23912714 EPHX1 Human Aroclor 1254 increases expression EXP 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of EPHX1 mRNA CTD PMID:17851650 EPHX1 Human Aroclor 1254 increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Chlorodiphenyl (54% Chlorine) results in increased expression of EPHX1 mRNA CTD PMID:18178546 EPHX1 Human arsenite(3-) multiple interactions ISO Ephx1 (Mus musculus) 6480464 TRP53 protein affects the reaction [arsenite results in increased expression of EPHX1 mRNA] CTD PMID:18929588 EPHX1 Human arsenite(3-) multiple interactions EXP 6480464 [sodium arsenite results in increased abundance of arsenite] which results in increased expression of EPHX1 mRNA CTD PMID:32076005 EPHX1 Human arsenite(3-) increases expression ISO Ephx1 (Mus musculus) 6480464 arsenite results in increased expression of EPHX1 mRNA CTD PMID:18929588 EPHX1 Human arsenous acid decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of EPHX1 mRNA CTD PMID:17547211 EPHX1 Human asbestos affects response to substance EXP 6480464 EPHX1 gene polymorphism affects the susceptibility to Asbestos and EPHX1 protein affects the susceptibility to Asbestos CTD PMID:15993904 and PMID:17159790 EPHX1 Human atazanavir sulfate multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA CTD PMID:32152650 EPHX1 Human atazanavir sulfate decreases expression EXP 6480464 Atazanavir Sulfate results in decreased expression of EPHX1 mRNA CTD PMID:32152650 EPHX1 Human atrazine increases expression EXP 6480464 Atrazine results in increased expression of EPHX1 mRNA CTD PMID:22378314 EPHX1 Human azathioprine increases expression EXP 6480464 Azathioprine results in increased expression of EPHX1 mRNA CTD PMID:22623647 EPHX1 Human barbiturates increases activity ISO Ephx1 (Rattus norvegicus) 6480464 Barbiturates results in increased activity of EPHX1 protein CTD PMID:1372805 EPHX1 Human benzene affects response to substance ISO Ephx1 (Mus musculus) 6480464 EPHX1 protein affects the susceptibility to Benzene CTD PMID:12655032 EPHX1 Human benzene increases expression EXP 6480464 Benzene results in increased expression of EPHX1 mRNA CTD PMID:33269480 EPHX1 Human benzene affects response to substance EXP 6480464 EPHX1 polymorphism affects the susceptibility to Benzene CTD PMID:18784359 and PMID:18836923 EPHX1 Human benzene multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of Benzene metabolite] more ... CTD PMID:8211999 EPHX1 Human benzene affects metabolic processing EXP 6480464 EPHX1 protein affects the metabolism of Benzene CTD PMID:10511268 EPHX1 Human benzene multiple interactions EXP 6480464 [EPHX1 protein affects the metabolism of Benzene] which affects the abundance of muconic acid CTD PMID:10511268 EPHX1 Human benzene increases expression ISO Ephx1 (Mus musculus) 6480464 Benzene results in increased expression of EPHX1 mRNA CTD PMID:17311802 EPHX1 Human benzene increases metabolic processing EXP 6480464 EPHX1 protein results in increased metabolism of Benzene CTD PMID:17885617 EPHX1 Human benzene affects expression ISO Ephx1 (Rattus norvegicus) 6480464 Benzene affects the expression of EPHX1 mRNA CTD PMID:15878777 EPHX1 Human benzene multiple interactions ISO Ephx1 (Mus musculus) 6480464 EPHX1 protein affects the reaction [Benzene results in increased expression of CDKN1A mRNA] CTD PMID:12655032 EPHX1 Human benzo[a]pyrene multiple interactions EXP 6480464 3' more ... CTD PMID:15298956 more ... EPHX1 Human benzo[a]pyrene decreases expression EXP 6480464 Benzo(a)pyrene results in decreased expression of EPHX1 mRNA CTD PMID:32234424 EPHX1 Human benzo[a]pyrene decreases methylation EXP 6480464 Benzo(a)pyrene results in decreased methylation of EPHX1 exon and Benzo(a)pyrene results in decreased methylation of EPHX1 promoter CTD PMID:27901495 EPHX1 Human benzo[a]pyrene increases methylation EXP 6480464 Benzo(a)pyrene results in increased methylation of EPHX1 3' UTR and Benzo(a)pyrene results in increased methylation of EPHX1 5' UTR CTD PMID:27901495 EPHX1 Human benzo[a]pyrene increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Benzo(a)pyrene results in increased expression of EPHX1 mRNA CTD PMID:24025706 EPHX1 Human benzo[a]pyrene multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [[CYP1A1 protein co-treated with POR protein co-treated with EPHX1 protein] results in increased oxidation of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene 7 more ... CTD PMID:24025706 and PMID:24530354 EPHX1 Human benzo[a]pyrene increases activity EXP 6480464 Benzo(a)pyrene results in increased activity of EPHX1 protein CTD PMID:16484233 EPHX1 Human benzo[a]pyrene increases expression ISO Ephx1 (Mus musculus) 6480464 Benzo(a)pyrene metabolite results in increased expression of EPHX1 mRNA more ... CTD PMID:19770486 more ... EPHX1 Human benzo[a]pyrene increases expression EXP 6480464 Benzo(a)pyrene results in increased expression of EPHX1 mRNA CTD PMID:15735009 more ... EPHX1 Human benzo[a]pyrene multiple interactions ISO Ephx1 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of EPHX1 mRNA more ... CTD PMID:22759596 more ... EPHX1 Human Benzo[a]pyrene-7,8-diol multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [[CYP1A1 protein co-treated with POR protein co-treated with EPHX1 protein] results in increased oxidation of Benzo(a)pyrene] which results in increased abundance of benzo(a)pyrene 7 and 8-dihydrodiol CTD PMID:24530354 EPHX1 Human Benzo[a]pyrene-7,8-oxide multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 CYP2C11 protein promotes the reaction [EPHX1 protein affects the hydrolysis of benzo(a)pyrene 7 and 8-oxide] CTD PMID:12051674 EPHX1 Human benzo[b]fluoranthene increases expression ISO Ephx1 (Mus musculus) 6480464 benzo(b)fluoranthene results in increased expression of EPHX1 mRNA CTD PMID:26377693 EPHX1 Human benzo[b]fluoranthene multiple interactions ISO Ephx1 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of EPHX1 mRNA CTD PMID:27858113 EPHX1 Human benzo[c]phenanthrene multiple interactions ISO Ephx1 (Mus musculus) 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of benzo(c)phenanthrene] and EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benzo(c)phenanthrene] CTD PMID:8961944 EPHX1 Human benzo[c]phenanthrene multiple interactions EXP 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of benzo(c)phenanthrene] and EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benzo(c)phenanthrene] CTD PMID:8961944 EPHX1 Human benzothiazole increases expression ISO Ephx1 (Rattus norvegicus) 6480464 benzothiazole results in increased expression of EPHX1 mRNA CTD PMID:8951341 EPHX1 Human beta-naphthoflavone increases expression EXP 6480464 beta-Naphthoflavone results in increased expression of EPHX1 mRNA CTD PMID:22258563 EPHX1 Human beta-naphthoflavone increases expression ISO Ephx1 (Mus musculus) 6480464 beta-Naphthoflavone results in increased expression of EPHX1 mRNA CTD PMID:23994337 EPHX1 Human beta-naphthoflavone decreases activity ISO Ephx1 (Mus musculus) 6480464 beta-Naphthoflavone results in decreased activity of EPHX1 protein CTD PMID:3621371 EPHX1 Human bexarotene increases expression ISO Ephx1 (Rattus norvegicus) 6480464 bexarotene results in increased expression of EPHX1 mRNA CTD PMID:23292798 EPHX1 Human bifenthrin increases expression ISO Ephx1 (Mus musculus) 6480464 bifenthrin results in increased expression of EPHX1 mRNA CTD PMID:26071804 EPHX1 Human bis(2-ethylhexyl) phthalate increases expression ISO Ephx1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased expression of EPHX1 mRNA and Diethylhexyl Phthalate results in increased expression of EPHX1 protein CTD PMID:19850644 more ... EPHX1 Human bis(2-ethylhexyl) phthalate increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Diethylhexyl Phthalate results in increased expression of EPHX1 mRNA CTD PMID:35970509 EPHX1 Human bis(2-ethylhexyl) phthalate multiple interactions ISO Ephx1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 EPHX1 Human bis(2-ethylhexyl) phthalate increases activity ISO Ephx1 (Mus musculus) 6480464 Diethylhexyl Phthalate results in increased activity of EPHX1 protein CTD PMID:3621371 EPHX1 Human bis(2-ethylhexyl) phthalate decreases activity ISO Ephx1 (Rattus norvegicus) 6480464 Diethylhexyl Phthalate results in decreased activity of EPHX1 protein CTD PMID:10528994 EPHX1 Human bisphenol A decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 bisphenol A results in decreased expression of EPHX1 mRNA and bisphenol A results in decreased expression of EPHX1 protein CTD PMID:24752506 more ... EPHX1 Human bisphenol A increases methylation EXP 6480464 bisphenol A results in increased methylation of EPHX1 gene CTD PMID:31601247 EPHX1 Human bisphenol A decreases expression EXP 6480464 bisphenol A results in decreased expression of EPHX1 protein CTD PMID:31675489 and PMID:37567409 EPHX1 Human bisphenol A decreases expression ISO Ephx1 (Mus musculus) 6480464 bisphenol A results in decreased expression of EPHX1 mRNA CTD PMID:32156529 and PMID:33221593 EPHX1 Human bisphenol A increases expression EXP 6480464 bisphenol A results in increased expression of EPHX1 mRNA and bisphenol A results in increased expression of EPHX1 protein CTD PMID:29275510 and PMID:33376534 EPHX1 Human bisphenol A affects expression EXP 6480464 bisphenol A affects the expression of EPHX1 mRNA CTD PMID:30903817 EPHX1 Human bisphenol A multiple interactions ISO Ephx1 (Mus musculus) 6480464 [Tetrachlorodibenzodioxin co-treated with 2 more ... CTD PMID:28433925 EPHX1 Human bisphenol A multiple interactions EXP 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of EPHX1 gene and [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of EPHX1 mRNA CTD PMID:28628672 and PMID:31601247 EPHX1 Human bisphenol A increases expression ISO Ephx1 (Rattus norvegicus) 6480464 bisphenol A results in increased expression of EPHX1 mRNA and bisphenol A results in increased expression of EPHX1 protein CTD PMID:27208089 EPHX1 Human bisphenol A affects expression ISO Ephx1 (Rattus norvegicus) 6480464 bisphenol A affects the expression of EPHX1 mRNA and bisphenol A affects the expression of EPHX1 protein CTD PMID:25181051 more ... EPHX1 Human bisphenol A multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of EPHX1 mRNA and [bisphenol A co-treated with Estradiol] results in decreased expression of EPHX1 mRNA CTD PMID:26496021 and PMID:36041667 EPHX1 Human bisphenol A affects response to substance EXP 6480464 EPHX1 polymorphism affects the susceptibility to bisphenol A CTD PMID:26922413 EPHX1 Human Bisphenol B increases expression EXP 6480464 bisphenol B results in increased expression of EPHX1 protein CTD PMID:34186270 EPHX1 Human bisphenol F multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol F] results in increased expression of EPHX1 mRNA CTD PMID:28628672 EPHX1 Human bisphenol F multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [bisphenol A co-treated with bisphenol F co-treated with bisphenol S] results in increased expression of EPHX1 mRNA CTD PMID:36041667 EPHX1 Human bisphenol F increases expression EXP 6480464 bisphenol F results in increased expression of EPHX1 protein CTD PMID:34186270 EPHX1 Human bisphenol F multiple interactions ISO Ephx1 (Mus musculus) 6480464 [bisphenol F co-treated with Tretinoin] results in decreased expression of EPHX1 mRNA CTD PMID:30951980 EPHX1 Human bromobenzene increases expression ISO Ephx1 (Rattus norvegicus) 6480464 bromobenzene results in increased expression of EPHX1 mRNA CTD PMID:12628495 more ... EPHX1 Human buspirone decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 Buspirone results in decreased expression of EPHX1 mRNA CTD PMID:24136188 EPHX1 Human buta-1,3-diene increases response to substance EXP 6480464 EPHX1 5' UTR polymorphism results in increased susceptibility to 1 more ... CTD PMID:11238181 more ... EPHX1 Human buta-1,3-diene increases response to substance ISO Ephx1 (Mus musculus) 6480464 EPHX1 gene mutant form results in increased susceptibility to 1 and 3-butadiene CTD PMID:12929123 and PMID:16730686 EPHX1 Human buta-1,3-diene multiple interactions EXP 6480464 GSTM1 gene polymorphism promotes the reaction [EPHX1 gene polymorphism results in increased susceptibility to 1 more ... CTD PMID:11238181 EPHX1 Human butanal decreases expression EXP 6480464 butyraldehyde results in decreased expression of EPHX1 mRNA CTD PMID:26079696 EPHX1 Human butylated hydroxyanisole increases activity ISO Ephx1 (Mus musculus) 6480464 Butylated Hydroxyanisole results in increased activity of EPHX1 protein CTD PMID:3621371 EPHX1 Human butyric acid multiple interactions EXP 6480464 Benzo(a)pyrene affects the reaction [Butyric Acid results in decreased expression of EPHX1 mRNA] CTD PMID:30439556 EPHX1 Human butyric acid decreases expression EXP 6480464 Butyric Acid results in decreased expression of EPHX1 mRNA CTD PMID:30439556 EPHX1 Human cadmium atom increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Cadmium results in increased expression of EPHX1 mRNA CTD PMID:17327699 EPHX1 Human cadmium dichloride decreases expression ISO Ephx1 (Mus musculus) 6480464 Cadmium Chloride results in decreased expression of EPHX1 mRNA CTD PMID:20061341 EPHX1 Human cadmium dichloride decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 Cadmium Chloride results in decreased expression of EPHX1 mRNA CTD PMID:25993096 EPHX1 Human cadmium dichloride increases expression ISO Ephx1 (Mus musculus) 6480464 Cadmium Chloride results in increased expression of EPHX1 mRNA CTD PMID:24982889 EPHX1 Human cadmium dichloride increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Cadmium Chloride results in increased expression of EPHX1 mRNA CTD PMID:17327699 EPHX1 Human cannabidiol increases expression ISO Ephx1 (Mus musculus) 6480464 Cannabidiol results in increased expression of EPHX1 mRNA CTD PMID:27256343 EPHX1 Human captan increases expression ISO Ephx1 (Mus musculus) 6480464 Captan results in increased expression of EPHX1 mRNA CTD PMID:31558096 EPHX1 Human carbamazepine increases expression EXP 6480464 Carbamazepine results in increased expression of EPHX1 mRNA CTD PMID:17112801 EPHX1 Human carbamazepine affects response to substance EXP 6480464 EPHX1 gene SNP affects the susceptibility to Carbamazepine and EPHX1 protein affects the susceptibility to Carbamazepine CTD PMID:19620853 and PMID:26555147 EPHX1 Human carbamazepine increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Carbamazepine results in increased expression of EPHX1 mRNA CTD PMID:17381134 EPHX1 Human carbamazepine-10,11-epoxide multiple interactions EXP 6480464 [EPHX1 gene SNP affects the metabolism of carbamazepine epoxide] which affects the chemical synthesis of 10 more ... CTD PMID:15692831 EPHX1 Human carbon nanotube decreases expression ISO Ephx1 (Mus musculus) 6480464 Nanotubes more ... CTD PMID:25554681 and PMID:25620056 EPHX1 Human carmustine decreases expression EXP 6480464 Carmustine results in decreased expression of EPHX1 mRNA CTD PMID:15980968 EPHX1 Human catechol multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of catechol] CTD PMID:8211999 EPHX1 Human CGP 52608 multiple interactions EXP 6480464 CGP 52608 promotes the reaction [RORA protein binds to EPHX1 gene] CTD PMID:28238834 EPHX1 Human chenodeoxycholic acid decreases expression EXP 6480464 Chenodeoxycholic Acid results in decreased expression of EPHX1 mRNA CTD PMID:27174168 EPHX1 Human chenodeoxycholic acid multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA more ... CTD PMID:32152650 EPHX1 Human chlorohydrocarbon multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [Hydrocarbons more ... CTD PMID:30744511 EPHX1 Human chloroprene increases expression ISO Ephx1 (Mus musculus) 6480464 Chloroprene results in increased expression of EPHX1 mRNA CTD PMID:23125180 EPHX1 Human chrysene multiple interactions ISO Ephx1 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of EPHX1 mRNA more ... CTD PMID:27858113 and PMID:8961944 EPHX1 Human chrysene multiple interactions EXP 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of chrysene] and EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of chrysene] CTD PMID:8961944 EPHX1 Human ciguatoxin CTX1B affects expression ISO Ephx1 (Mus musculus) 6480464 Ciguatoxins affects the expression of EPHX1 mRNA CTD PMID:18353800 EPHX1 Human cisplatin increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Cisplatin results in increased expression of EPHX1 mRNA CTD PMID:18246545 EPHX1 Human cisplatin increases expression EXP 6480464 Cisplatin results in increased expression of EPHX1 mRNA CTD PMID:27392435 EPHX1 Human cisplatin multiple interactions EXP 6480464 [Cisplatin co-treated with jinfukang] results in increased expression of EPHX1 mRNA CTD PMID:27392435 EPHX1 Human cisplatin increases expression ISO Ephx1 (Mus musculus) 6480464 Cisplatin results in increased expression of EPHX1 mRNA CTD PMID:21151649 and PMID:21382384 EPHX1 Human cisplatin affects expression ISO Ephx1 (Rattus norvegicus) 6480464 Cisplatin affects the expression of EPHX1 mRNA CTD PMID:18246545 EPHX1 Human clofibrate decreases activity ISO Ephx1 (Rattus norvegicus) 6480464 Clofibrate results in decreased activity of EPHX1 protein CTD PMID:10528994 EPHX1 Human clofibrate increases activity ISO Ephx1 (Mus musculus) 6480464 Clofibrate results in increased activity of EPHX1 protein CTD PMID:3621371 EPHX1 Human clofibrate increases expression ISO Ephx1 (Mus musculus) 6480464 Clofibrate results in increased expression of EPHX1 protein CTD PMID:3318844 and PMID:4049385 EPHX1 Human clomipramine affects expression ISO Ephx1 (Rattus norvegicus) 6480464 Clomipramine affects the expression of EPHX1 mRNA CTD PMID:18355885 EPHX1 Human clonazepam increases activity ISO Ephx1 (Rattus norvegicus) 6480464 Clonazepam results in increased activity of EPHX1 protein CTD PMID:1372805 EPHX1 Human clotrimazole increases activity ISO Ephx1 (Rattus norvegicus) 6480464 Clotrimazole results in increased activity of EPHX1 protein CTD PMID:1372805 EPHX1 Human cobalt dichloride increases expression EXP 6480464 cobaltous chloride results in increased expression of EPHX1 mRNA CTD PMID:19320972 EPHX1 Human cobalt dichloride decreases expression EXP 6480464 cobaltous chloride results in decreased expression of EPHX1 mRNA CTD PMID:19376846 EPHX1 Human colforsin daropate hydrochloride affects expression EXP 6480464 Colforsin affects the expression of EPHX1 mRNA CTD PMID:20726872 EPHX1 Human colforsin daropate hydrochloride multiple interactions EXP 6480464 Valproic Acid affects the reaction [Colforsin affects the expression of EPHX1 mRNA] CTD PMID:20726872 EPHX1 Human copper atom multiple interactions EXP 6480464 [Thiosemicarbazones binds to Copper] which results in decreased expression of EPHX1 protein CTD PMID:20931265 EPHX1 Human copper(0) multiple interactions EXP 6480464 [Thiosemicarbazones binds to Copper] which results in decreased expression of EPHX1 protein CTD PMID:20931265 EPHX1 Human copper(II) chloride increases expression EXP 6480464 cupric chloride results in increased expression of EPHX1 mRNA CTD PMID:38568856 EPHX1 Human copper(II) sulfate decreases expression EXP 6480464 Copper Sulfate results in decreased expression of EPHX1 mRNA CTD PMID:19549813 EPHX1 Human coumarin increases expression ISO Ephx1 (Mus musculus) 6480464 coumarin results in increased expression of EPHX1 mRNA CTD PMID:17311802 EPHX1 Human CU-O LINKAGE decreases expression EXP 6480464 cupric oxide results in decreased expression of EPHX1 mRNA CTD PMID:32285662 EPHX1 Human Cuprizon increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Cuprizone results in increased expression of EPHX1 mRNA CTD PMID:27523638 EPHX1 Human cyclophosphamide affects expression ISO Ephx1 (Rattus norvegicus) 6480464 Cyclophosphamide affects the expression of EPHX1 mRNA CTD PMID:18246545 EPHX1 Human cyclophosphamide increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Cyclophosphamide results in increased expression of EPHX1 mRNA CTD PMID:18246545 EPHX1 Human cyclosporin A decreases expression EXP 6480464 Cyclosporine results in decreased expression of EPHX1 mRNA CTD PMID:20106945 and PMID:27989131 EPHX1 Human cyclosporin A multiple interactions EXP 6480464 [Cyclosporine co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA CTD PMID:32152650 EPHX1 Human cypermethrin increases expression ISO Ephx1 (Rattus norvegicus) 6480464 cypermethrin results in increased expression of EPHX1 mRNA CTD PMID:22528246 EPHX1 Human cyproconazole increases expression ISO Ephx1 (Mus musculus) 6480464 cyproconazole results in increased expression of EPHX1 mRNA CTD PMID:22334560 EPHX1 Human cyproconazole increases expression ISO Ephx1 (Rattus norvegicus) 6480464 cyproconazole results in increased expression of EPHX1 mRNA CTD PMID:29038839 EPHX1 Human cyproconazole multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [cyproconazole co-treated with epoxiconazole] results in increased expression of EPHX1 mRNA CTD PMID:29038839 EPHX1 Human DDE decreases expression EXP 6480464 Dichlorodiphenyl Dichloroethylene results in decreased expression of EPHX1 mRNA CTD PMID:38568856 EPHX1 Human DDT increases activity ISO Ephx1 (Rattus norvegicus) 6480464 DDT results in increased activity of EPHX1 protein CTD PMID:1372805 EPHX1 Human decabromodiphenyl ether increases expression ISO Ephx1 (Rattus norvegicus) 6480464 decabromobiphenyl ether results in increased expression of EPHX1 mRNA CTD PMID:32679240 EPHX1 Human decabromodiphenyl ether increases expression EXP 6480464 decabromobiphenyl ether results in increased expression of EPHX1 protein CTD PMID:31675489 EPHX1 Human deoxycholic acid multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA more ... CTD PMID:32152650 EPHX1 Human deoxynivalenol decreases expression ISO Ephx1 (Mus musculus) 6480464 deoxynivalenol results in decreased expression of EPHX1 mRNA CTD PMID:15371230 EPHX1 Human dexamethasone multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of EPHX1 mRNA more ... CTD PMID:28628672 EPHX1 Human dextran sulfate decreases expression ISO Ephx1 (Mus musculus) 6480464 Dextran Sulfate results in decreased expression of EPHX1 mRNA CTD PMID:35093514 EPHX1 Human Diallyl sulfide increases activity ISO Ephx1 (Rattus norvegicus) 6480464 allyl sulfide results in increased activity of EPHX1 protein CTD PMID:1372805 EPHX1 Human Diallyl sulfide increases expression ISO Ephx1 (Rattus norvegicus) 6480464 allyl sulfide results in increased expression of EPHX1 mRNA CTD PMID:19695238 EPHX1 Human diallyl trisulfide increases expression ISO Ephx1 (Rattus norvegicus) 6480464 diallyl trisulfide results in increased expression of EPHX1 mRNA CTD PMID:20650352 EPHX1 Human diarsenic trioxide decreases expression EXP 6480464 Arsenic Trioxide results in decreased expression of EPHX1 mRNA CTD PMID:17547211 EPHX1 Human diazinon decreases expression ISO Ephx1 (Mus musculus) 6480464 Diazinon results in decreased expression of EPHX1 mRNA CTD PMID:17311802 EPHX1 Human dibenz[a,h]anthracene multiple interactions ISO Ephx1 (Mus musculus) 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of 1 more ... CTD PMID:8961944 EPHX1 Human dibenz[a,h]anthracene increases expression ISO Ephx1 (Mus musculus) 6480464 1 more ... CTD PMID:26377693 EPHX1 Human dibenz[a,h]anthracene multiple interactions EXP 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of 1 more ... CTD PMID:8961944 EPHX1 Human dibenzofurans increases expression ISO Ephx1 (Mus musculus) 6480464 Dibenzofurans results in increased expression of EPHX1 mRNA CTD PMID:34254344 EPHX1 Human dibenzoylmethane increases activity ISO Ephx1 (Mus musculus) 6480464 dibenzoylmethane results in increased activity of EPHX1 protein CTD PMID:3621371 EPHX1 Human dibenzoylmethane multiple interactions ISO Ephx1 (Mus musculus) 6480464 [sulforaphane co-treated with dibenzoylmethane] results in increased expression of EPHX1 mRNA CTD PMID:17942926 EPHX1 Human dibenzoylmethane increases expression ISO Ephx1 (Mus musculus) 6480464 dibenzoylmethane results in increased expression of EPHX1 mRNA CTD PMID:17942926 EPHX1 Human Dibutyl phosphate affects expression EXP 6480464 di-n-butylphosphoric acid affects the expression of EPHX1 mRNA CTD PMID:37042841 EPHX1 Human dibutyl phthalate decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 Dibutyl Phthalate results in decreased expression of EPHX1 mRNA CTD PMID:21266533 EPHX1 Human dibutyl phthalate decreases expression ISO Ephx1 (Mus musculus) 6480464 Dibutyl Phthalate results in decreased expression of EPHX1 mRNA CTD PMID:17361019 EPHX1 Human dichloroacetic acid increases expression ISO Ephx1 (Mus musculus) 6480464 Dichloroacetic Acid results in increased expression of EPHX1 mRNA CTD PMID:28962523 EPHX1 Human diclofenac decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 Diclofenac results in decreased expression of EPHX1 mRNA CTD PMID:17202759 EPHX1 Human dieldrin multiple interactions ISO Ephx1 (Mus musculus) 6480464 Dieldrin promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide] CTD PMID:2043152 EPHX1 Human diepoxybutane affects response to substance EXP 6480464 EPHX1 gene polymorphism affects the susceptibility to diepoxybutane CTD PMID:15036125 EPHX1 Human diepoxybutane increases response to substance ISO Ephx1 (Mus musculus) 6480464 EPHX1 gene mutant form results in increased susceptibility to diepoxybutane CTD PMID:12929123 EPHX1 Human diethylstilbestrol increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Diethylstilbestrol results in increased expression of EPHX1 mRNA CTD PMID:15890375 EPHX1 Human Dihydroxycarbazepine multiple interactions EXP 6480464 [EPHX1 gene SNP affects the metabolism of carbamazepine epoxide] which affects the chemical synthesis of 10 more ... CTD PMID:15692831 EPHX1 Human dioxygen multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [dan-shen root extract co-treated with Andrographis paniculata extract] inhibits the reaction [[Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of EPHX1 mRNA] and [Oxygen deficiency co-treated with Blood Glucose deficiency co-treated with Particulate Matter] results in decreased expression of EPHX1 mRNA CTD PMID:33729688 EPHX1 Human dipotassium bis[mu-tartrato(4-)]diantimonate(2-) trihydrate multiple interactions EXP 6480464 [Antimony Potassium Tartrate results in increased abundance of antimonite] which results in increased expression of EPHX1 mRNA CTD PMID:32076005 EPHX1 Human diuron increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Diuron results in increased expression of EPHX1 mRNA CTD PMID:21551480 EPHX1 Human dorsomorphin multiple interactions EXP 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPHX1 mRNA CTD PMID:27188386 EPHX1 Human doxorubicin increases expression EXP 6480464 Doxorubicin results in increased expression of EPHX1 mRNA CTD PMID:15205334 and PMID:29803840 EPHX1 Human doxorubicin increases expression ISO Ephx1 (Mus musculus) 6480464 Doxorubicin results in increased expression of EPHX1 mRNA CTD PMID:21382384 and PMID:22016648 EPHX1 Human doxorubicin increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Doxorubicin results in increased expression of EPHX1 mRNA CTD PMID:19915844 EPHX1 Human endosulfan affects expression ISO Ephx1 (Rattus norvegicus) 6480464 Endosulfan affects the expression of EPHX1 mRNA CTD PMID:29391264 EPHX1 Human epoxiconazole increases expression ISO Ephx1 (Rattus norvegicus) 6480464 epoxiconazole results in increased expression of EPHX1 mRNA CTD PMID:25182419 EPHX1 Human epoxiconazole decreases expression ISO Ephx1 (Mus musculus) 6480464 epoxiconazole results in decreased expression of EPHX1 mRNA CTD PMID:35436446 EPHX1 Human epoxiconazole multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [cyproconazole co-treated with epoxiconazole] results in increased expression of EPHX1 mRNA CTD PMID:29038839 EPHX1 Human epoxiconazole increases expression ISO Ephx1 (Mus musculus) 6480464 epoxiconazole results in increased expression of EPHX1 mRNA CTD PMID:22334560 EPHX1 Human Erucin increases expression ISO Ephx1 (Rattus norvegicus) 6480464 erucin results in increased expression of EPHX1 protein CTD PMID:21132492 EPHX1 Human estradiol increases activity ISO Ephx1 (Rattus norvegicus) 152998935 estradiol increases Ephx1 enzyme activity in rat liver microsomes RGD EPHX1 Human ethanol increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Ethanol results in increased expression of EPHX1 mRNA CTD PMID:23273579 EPHX1 Human ethanol multiple interactions ISO Ephx1 (Mus musculus) 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of EPHX1 mRNA CTD PMID:30517762 EPHX1 Human ethoxyquin increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Ethoxyquin results in increased expression of EPHX1 mRNA CTD PMID:19695238 EPHX1 Human ethylparaben increases expression EXP 6480464 ethyl-p-hydroxybenzoate results in increased expression of EPHX1 mRNA CTD PMID:37690743 EPHX1 Human etoposide increases expression ISO Ephx1 (Mus musculus) 6480464 Etoposide results in increased expression of EPHX1 mRNA CTD PMID:21382384 and PMID:25270620 EPHX1 Human felbamate increases expression ISO Ephx1 (Rattus norvegicus) 6480464 felbamate results in increased expression of EPHX1 mRNA CTD PMID:17381134 EPHX1 Human fenamidone increases expression ISO Ephx1 (Mus musculus) 6480464 fenamidone results in increased expression of EPHX1 mRNA CTD PMID:27029645 EPHX1 Human fenvalerate increases activity ISO Ephx1 (Rattus norvegicus) 6480464 fenvalerate metabolite results in increased activity of EPHX1 protein CTD PMID:10630566 EPHX1 Human finasteride increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Finasteride results in increased expression of EPHX1 mRNA CTD PMID:24136188 EPHX1 Human fipronil increases expression ISO Ephx1 (Rattus norvegicus) 6480464 fipronil results in increased expression of EPHX1 mRNA CTD PMID:23962444 EPHX1 Human flutamide increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Flutamide results in increased expression of EPHX1 mRNA CTD PMID:24136188 EPHX1 Human folpet increases expression ISO Ephx1 (Mus musculus) 6480464 folpet results in increased expression of EPHX1 mRNA CTD PMID:31558096 EPHX1 Human fulvestrant multiple interactions EXP 6480464 [bisphenol A co-treated with Fulvestrant] results in increased methylation of EPHX1 gene CTD PMID:31601247 EPHX1 Human fumonisin B1 increases expression ISO Ephx1 (Mus musculus) 6480464 fumonisin B1 results in increased expression of EPHX1 mRNA CTD PMID:16221962 EPHX1 Human furan increases methylation ISO Ephx1 (Rattus norvegicus) 6480464 furan results in increased methylation of EPHX1 gene CTD PMID:22079235 EPHX1 Human furan increases expression ISO Ephx1 (Rattus norvegicus) 6480464 furan results in increased expression of EPHX1 mRNA CTD PMID:25539665 and PMID:26194646 EPHX1 Human furan increases expression ISO Ephx1 (Mus musculus) 6480464 furan results in increased expression of EPHX1 mRNA CTD PMID:24183702 and PMID:37517673 EPHX1 Human genistein increases expression EXP 6480464 Genistein results in increased expression of EPHX1 mRNA CTD PMID:18847459 EPHX1 Human gentamycin decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 Gentamicins results in decreased expression of EPHX1 mRNA CTD PMID:33387578 EPHX1 Human glafenine decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 Glafenine results in decreased expression of EPHX1 mRNA CTD PMID:24136188 EPHX1 Human glucoerucin increases expression ISO Ephx1 (Rattus norvegicus) 6480464 glucoerucin results in increased expression of EPHX1 protein CTD PMID:21132492 EPHX1 Human glucoerucin(1-) increases expression ISO Ephx1 (Rattus norvegicus) 6480464 glucoerucin results in increased expression of EPHX1 protein CTD PMID:21132492 EPHX1 Human glucoraphanin increases expression ISO Ephx1 (Rattus norvegicus) 6480464 glucoraphanin results in increased expression of EPHX1 protein CTD PMID:21132492 EPHX1 Human glutathione increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Glutathione deficiency results in increased expression of EPHX1 mRNA CTD PMID:15345336 EPHX1 Human glycochenodeoxycholic acid multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA more ... CTD PMID:32152650 EPHX1 Human glycocholic acid multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA more ... CTD PMID:32152650 EPHX1 Human glycodeoxycholic acid multiple interactions EXP 6480464 [Atazanavir Sulfate co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA more ... CTD PMID:32152650 EPHX1 Human gold atom increases expression EXP 6480464 Gold analog results in increased expression of EPHX1 mRNA CTD PMID:36057382 EPHX1 Human gold(0) increases expression EXP 6480464 Gold analog results in increased expression of EPHX1 mRNA CTD PMID:36057382 EPHX1 Human Heliotrine increases expression ISO Ephx1 (Rattus norvegicus) 6480464 heliotrine results in increased expression of EPHX1 mRNA CTD PMID:32419051 EPHX1 Human Heptachlor epoxide multiple interactions ISO Ephx1 (Mus musculus) 6480464 Heptachlor Epoxide promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide] CTD PMID:2043152 EPHX1 Human Hexachloro-1,3-butadiene increases expression ISO Ephx1 (Rattus norvegicus) 6480464 hexachlorobutadiene results in increased expression of EPHX1 mRNA CTD PMID:21905055 EPHX1 Human hexachlorobenzene increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Hexachlorobenzene results in increased expression of EPHX1 mRNA CTD PMID:15159207 EPHX1 Human HT-2 toxin increases expression EXP 6480464 HT-2 toxin results in increased expression of EPHX1 mRNA CTD PMID:22982764 EPHX1 Human hydrogen peroxide increases expression ISO Ephx1 (Mus musculus) 6480464 Hydrogen Peroxide results in increased expression of EPHX1 mRNA CTD PMID:21382384 EPHX1 Human hydroquinone multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of hydroquinone] and EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Phenol] which results in increased chemical synthesis of hydroquinone] CTD PMID:8211999 EPHX1 Human imipramine affects expression ISO Ephx1 (Rattus norvegicus) 6480464 Imipramine affects the expression of EPHX1 mRNA CTD PMID:18355885 EPHX1 Human indole-3-methanol affects expression ISO Ephx1 (Rattus norvegicus) 6480464 indole-3-carbinol affects the expression of EPHX1 mRNA CTD PMID:21396975 EPHX1 Human indometacin multiple interactions EXP 6480464 [INS protein co-treated with Dexamethasone co-treated with 1-Methyl-3-isobutylxanthine co-treated with Indomethacin co-treated with bisphenol A] results in increased expression of EPHX1 mRNA more ... CTD PMID:28628672 EPHX1 Human inulin multiple interactions ISO Ephx1 (Mus musculus) 6480464 [perfluorooctane sulfonic acid co-treated with Inulin] results in increased expression of EPHX1 mRNA CTD PMID:36331819 EPHX1 Human ivermectin decreases expression EXP 6480464 Ivermectin results in decreased expression of EPHX1 protein CTD PMID:32959892 EPHX1 Human ketoconazole affects expression ISO Ephx1 (Rattus norvegicus) 6480464 Ketoconazole affects the expression of EPHX1 mRNA CTD PMID:18355885 EPHX1 Human ketoconazole increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Ketoconazole results in increased expression of EPHX1 mRNA CTD PMID:37077353 EPHX1 Human kojic acid multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of EPHX1 mRNA and [Diethylnitrosamine co-treated with kojic acid] results in increased expression of EPHX1 mRNA CTD PMID:18544905 EPHX1 Human L-ascorbic acid multiple interactions EXP 6480464 [Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX1 mRNA CTD PMID:17639512 EPHX1 Human lanosterol multiple interactions ISO Ephx1 (Mus musculus) 6480464 Lanosterol analog inhibits the reaction [EPHX1 protein results in increased metabolism of cholesterol alpha-oxide] CTD PMID:2043152 EPHX1 Human lead diacetate increases expression EXP 6480464 lead acetate results in increased expression of EPHX1 mRNA CTD PMID:38568856 EPHX1 Human lead(0) affects expression EXP 6480464 Lead affects the expression of EPHX1 mRNA CTD PMID:28903495 EPHX1 Human levofloxacin decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 Levofloxacin results in decreased expression of EPHX1 mRNA CTD PMID:24136188 EPHX1 Human lithocholic acid multiple interactions ISO Ephx1 (Mus musculus) 6480464 [Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in increased expression of EPHX1 mRNA CTD PMID:20359477 EPHX1 Human m-xylene increases expression EXP 6480464 3-xylene results in increased expression of EPHX1 mRNA CTD PMID:33269480 EPHX1 Human malathion decreases expression ISO Ephx1 (Mus musculus) 6480464 Malathion results in decreased expression of EPHX1 mRNA CTD PMID:17311802 EPHX1 Human mandelic acid multiple interactions EXP 6480464 EPHX1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 EPHX1 Human medroxyprogesterone acetate multiple interactions EXP 6480464 ESR1 protein promotes the reaction [Medroxyprogesterone Acetate results in increased expression of EPHX1 protein] CTD PMID:20383792 EPHX1 Human medroxyprogesterone acetate increases expression EXP 6480464 Medroxyprogesterone Acetate results in increased expression of EPHX1 mRNA and Medroxyprogesterone Acetate results in increased expression of EPHX1 protein CTD PMID:20383792 EPHX1 Human menadione increases expression ISO Ephx1 (Mus musculus) 6480464 Vitamin K 3 results in increased expression of EPHX1 mRNA CTD PMID:21382384 EPHX1 Human mercury dichloride increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Mercuric Chloride results in increased expression of EPHX1 mRNA CTD PMID:32599119 EPHX1 Human methamphetamine multiple interactions ISO Ephx1 (Mus musculus) 6480464 EPHX1 protein affects the reaction [Methamphetamine results in decreased expression of BCL2 protein] more ... CTD PMID:31422080 EPHX1 Human methamphetamine increases methylation ISO Ephx1 (Mus musculus) 6480464 Methamphetamine results in increased methylation of EPHX1 promoter CTD PMID:26307267 EPHX1 Human methamphetamine increases expression ISO Ephx1 (Mus musculus) 6480464 Methamphetamine results in increased expression of EPHX1 mRNA and Methamphetamine results in increased expression of EPHX1 protein CTD PMID:26307267 and PMID:31422080 EPHX1 Human methapyrilene increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Methapyrilene results in increased expression of EPHX1 mRNA CTD PMID:15890375 EPHX1 Human methyl methanesulfonate increases expression ISO Ephx1 (Mus musculus) 6480464 Methyl Methanesulfonate results in increased expression of EPHX1 mRNA CTD PMID:21382384 EPHX1 Human methylmercury chloride multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [Hydrocarbons more ... CTD PMID:30744511 EPHX1 Human mitomycin C increases expression ISO Ephx1 (Mus musculus) 6480464 Mitomycin results in increased expression of EPHX1 mRNA CTD PMID:21382384 EPHX1 Human mono(2-ethylhexyl) phthalate increases expression ISO Ephx1 (Rattus norvegicus) 6480464 mono-(2-ethylhexyl)phthalate results in increased expression of EPHX1 mRNA CTD PMID:12706301 EPHX1 Human muconic acid multiple interactions EXP 6480464 [EPHX1 protein affects the metabolism of Benzene] which affects the abundance of muconic acid CTD PMID:10511268 EPHX1 Human N,N'-diphenylthiourea increases expression ISO Ephx1 (Rattus norvegicus) 6480464 diphenylthiourea results in increased expression of EPHX1 mRNA and diphenylthiourea results in increased expression of EPHX1 protein CTD PMID:10190572 EPHX1 Human N,N-diethyl-m-toluamide increases expression EXP 6480464 DEET results in increased expression of EPHX1 mRNA CTD PMID:27091632 EPHX1 Human N-benzyloxycarbonyl-L-leucyl-L-leucyl-L-leucinal increases expression ISO Ephx1 (Mus musculus) 6480464 benzyloxycarbonylleucyl-leucyl-leucine aldehyde results in increased expression of EPHX1 mRNA CTD PMID:20061341 EPHX1 Human N-ethyl-N-nitrosourea increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Ethylnitrosourea results in increased expression of EPHX1 mRNA CTD PMID:15954086 EPHX1 Human N-methyl-N-nitrosourea increases expression ISO Ephx1 (Mus musculus) 6480464 Methylnitrosourea results in increased expression of EPHX1 mRNA CTD PMID:21382384 EPHX1 Human N-Methylolacrylamide decreases expression ISO Ephx1 (Mus musculus) 6480464 N-methylolacrylamide results in decreased expression of EPHX1 mRNA CTD PMID:17311802 EPHX1 Human N-nitrosodiethylamine multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with kojic acid co-treated with Diethylnitrosamine] results in decreased expression of EPHX1 mRNA more ... CTD PMID:18544905 more ... EPHX1 Human N-nitrosodiethylamine increases expression ISO Ephx1 (Mus musculus) 6480464 Diethylnitrosamine results in increased expression of EPHX1 mRNA CTD PMID:17854601 and PMID:21607683 EPHX1 Human N-nitrosodiethylamine increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Diethylnitrosamine results in increased expression of EPHX1 mRNA CTD PMID:17602206 more ... EPHX1 Human N-nitrosodiethylamine multiple interactions ISO Ephx1 (Mus musculus) 6480464 RB1 protein inhibits the reaction [Diethylnitrosamine results in increased expression of EPHX1 mRNA] CTD PMID:17854601 EPHX1 Human N-nitrosodimethylamine increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Dimethylnitrosamine results in increased expression of EPHX1 mRNA CTD PMID:14600272 and PMID:15890375 EPHX1 Human naphthalene increases expression EXP 6480464 naphthalene results in increased expression of EPHX1 mRNA CTD PMID:20500019 EPHX1 Human naphthalene increases response to substance ISO Ephx1 (Mus musculus) 6480464 EPHX1 results in increased susceptibility to naphthalene CTD PMID:26840748 EPHX1 Human naphthalene increases metabolic processing ISO Ephx1 (Mus musculus) 6480464 EPHX1 protein results in increased metabolism of naphthalene CTD PMID:18363382 and PMID:26840748 EPHX1 Human naphthalene multiple interactions ISO Ephx1 (Mus musculus) 6480464 [EPHX1 protein results in increased metabolism of naphthalene] which results in increased chemical synthesis of 1 more ... CTD PMID:18363382 and PMID:26840748 EPHX1 Human naphthalene-1,5-diamine affects expression ISO Ephx1 (Mus musculus) 6480464 1 and 5-naphthalenediamine affects the expression of EPHX1 mRNA CTD PMID:17114358 EPHX1 Human naphthalene-1,5-diamine increases expression ISO Ephx1 (Mus musculus) 6480464 1 and 5-naphthalenediamine results in increased expression of EPHX1 mRNA CTD PMID:17311802 EPHX1 Human nefazodone increases expression ISO Ephx1 (Rattus norvegicus) 6480464 nefazodone results in increased expression of EPHX1 mRNA CTD PMID:24136188 EPHX1 Human nefazodone multiple interactions EXP 6480464 [nefazodone co-treated with Glycochenodeoxycholic Acid co-treated with Deoxycholic Acid co-treated with Chenodeoxycholic Acid co-treated with Glycodeoxycholic Acid co-treated with Glycocholic Acid] results in decreased expression of EPHX1 mRNA CTD PMID:32152650 EPHX1 Human nefazodone decreases expression EXP 6480464 nefazodone results in decreased expression of EPHX1 mRNA CTD PMID:32152650 EPHX1 Human nickel atom decreases expression EXP 6480464 Nickel results in decreased expression of EPHX1 mRNA CTD PMID:25583101 EPHX1 Human nimesulide increases expression ISO Ephx1 (Rattus norvegicus) 6480464 nimesulide results in increased expression of EPHX1 mRNA CTD PMID:24136188 EPHX1 Human nimesulide decreases glutathionylation EXP 6480464 EPHX1 protein results in decreased glutathionylation of nimesulide CTD PMID:26524229 EPHX1 Human nitrofen increases expression ISO Ephx1 (Rattus norvegicus) 6480464 nitrofen results in increased expression of EPHX1 mRNA CTD PMID:33484710 EPHX1 Human Nutlin-3 multiple interactions EXP 6480464 [Dactinomycin co-treated with nutlin 3] results in increased secretion of EPHX1 protein CTD PMID:38460933 EPHX1 Human ochratoxin A increases expression EXP 6480464 ochratoxin A results in increased expression of EPHX1 mRNA CTD PMID:32905824 EPHX1 Human organoselenium compound increases activity ISO Ephx1 (Mus musculus) 6480464 Organoselenium Compounds results in increased activity of EPHX1 protein CTD PMID:17163488 EPHX1 Human oxaliplatin multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of EPHX1 mRNA CTD PMID:25729387 EPHX1 Human oxaliplatin increases expression ISO Ephx1 (Rattus norvegicus) 6480464 oxaliplatin results in increased expression of EPHX1 mRNA CTD PMID:25729387 EPHX1 Human oxirane affects metabolic processing EXP 6480464 EPHX1 protein affects the metabolism of Ethylene Oxide CTD PMID:11437638 EPHX1 Human oxirane affects metabolic processing ISO Ephx1 (Rattus norvegicus) 6480464 EPHX1 protein affects the metabolism of Ethylene Oxide CTD PMID:11437638 EPHX1 Human ozone decreases expression ISO Ephx1 (Mus musculus) 6480464 Ozone results in decreased expression of EPHX1 mRNA CTD PMID:12763052 EPHX1 Human ozone multiple interactions ISO Ephx1 (Mus musculus) 6480464 [Air Pollutants results in increased abundance of [Ozone co-treated with Soot]] which results in decreased expression of EPHX1 mRNA CTD PMID:34911549 EPHX1 Human p-toluidine increases expression ISO Ephx1 (Rattus norvegicus) 6480464 4-toluidine results in increased expression of EPHX1 mRNA CTD PMID:27638505 EPHX1 Human paracetamol affects expression ISO Ephx1 (Mus musculus) 6480464 Acetaminophen affects the expression of EPHX1 mRNA CTD PMID:15606129 and PMID:17562736 EPHX1 Human paracetamol increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Acetaminophen results in increased expression of EPHX1 mRNA CTD PMID:30723492 and PMID:33387578 EPHX1 Human paracetamol increases expression EXP 6480464 Acetaminophen results in increased expression of EPHX1 mRNA CTD PMID:22230336 EPHX1 Human paracetamol multiple interactions ISO Ephx1 (Mus musculus) 6480464 [Acetaminophen results in increased activity of and results in increased localization of NFE2L2 protein] which results in increased expression of EPHX1 mRNA CTD PMID:15122755 EPHX1 Human pentachloronitrobenzene increases expression ISO Ephx1 (Mus musculus) 6480464 quintozene results in increased expression of EPHX1 mRNA CTD PMID:17311802 EPHX1 Human pentachlorophenol increases expression ISO Ephx1 (Mus musculus) 6480464 Pentachlorophenol results in increased expression of EPHX1 mRNA CTD PMID:23892564 EPHX1 Human perfluorooctane-1-sulfonic acid increases expression ISO Ephx1 (Rattus norvegicus) 6480464 perfluorooctane sulfonic acid results in increased expression of EPHX1 mRNA CTD PMID:19162173 EPHX1 Human perfluorooctane-1-sulfonic acid multiple interactions ISO Ephx1 (Mus musculus) 6480464 [Dietary Fats co-treated with perfluorooctane sulfonic acid] results in increased expression of EPHX1 mRNA more ... CTD PMID:32979393 and PMID:36331819 EPHX1 Human perfluorooctane-1-sulfonic acid increases expression EXP 6480464 perfluorooctane sulfonic acid results in increased expression of EPHX1 mRNA CTD PMID:27153767 EPHX1 Human perfluorooctane-1-sulfonic acid increases expression ISO Ephx1 (Mus musculus) 6480464 perfluorooctane sulfonic acid results in increased expression of EPHX1 mRNA and perfluorooctane sulfonic acid results in increased expression of EPHX1 protein CTD PMID:20936131 and PMID:32979393 EPHX1 Human perfluorooctane-1-sulfonic acid affects expression ISO Ephx1 (Mus musculus) 6480464 perfluorooctane sulfonic acid affects the expression of EPHX1 mRNA CTD PMID:19429403 EPHX1 Human perfluorooctanoic acid affects expression ISO Ephx1 (Mus musculus) 6480464 perfluorooctanoic acid affects the expression of EPHX1 mRNA CTD PMID:18281256 and PMID:19429403 EPHX1 Human perfluorooctanoic acid decreases expression ISO Ephx1 (Mus musculus) 6480464 perfluorooctanoic acid results in decreased expression of EPHX1 protein CTD PMID:28126411 EPHX1 Human perfluorooctanoic acid increases expression ISO Ephx1 (Mus musculus) 6480464 perfluorooctanoic acid results in increased expression of EPHX1 mRNA CTD PMID:23626681 and PMID:37422089 EPHX1 Human perfluorooctanoic acid multiple interactions ISO Ephx1 (Mus musculus) 6480464 [perfluorooctanoic acid co-treated with Dietary Fats and Unsaturated] results in increased expression of EPHX1 mRNA CTD PMID:23626681 EPHX1 Human permethrin increases expression ISO Ephx1 (Mus musculus) 6480464 Permethrin results in increased expression of EPHX1 mRNA CTD PMID:30629241 EPHX1 Human phenethyl isothiocyanate increases expression ISO Ephx1 (Rattus norvegicus) 6480464 phenethyl isothiocyanate results in increased expression of EPHX1 protein CTD PMID:21132492 EPHX1 Human phenobarbital multiple interactions ISO Ephx1 (Mus musculus) 6480464 NR1I3 protein affects the reaction [Phenobarbital results in increased expression of EPHX1 mRNA] and NR1I3 protein promotes the reaction [Phenobarbital results in increased expression of EPHX1 mRNA] CTD PMID:19482888 and PMID:19850644 EPHX1 Human phenobarbital decreases expression ISO Ephx1 (Mus musculus) 6480464 Phenobarbital results in decreased expression of EPHX1 protein CTD PMID:35881160 EPHX1 Human phenobarbital increases expression EXP 6480464 Phenobarbital results in increased expression of EPHX1 mRNA and Phenobarbital results in increased expression of EPHX1 protein CTD PMID:22258563 more ... EPHX1 Human phenobarbital affects expression ISO Ephx1 (Mus musculus) 6480464 Phenobarbital affects the expression of EPHX1 mRNA CTD PMID:23091169 EPHX1 Human phenobarbital increases expression ISO Ephx1 (Mus musculus) 6480464 Phenobarbital results in increased expression of EPHX1 mRNA CTD PMID:19482888 more ... EPHX1 Human phenobarbital increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Phenobarbital results in increased expression of EPHX1 mRNA and Phenobarbital results in increased expression of EPHX1 protein CTD PMID:11328961 more ... EPHX1 Human phenobarbital affects expression EXP 6480464 Phenobarbital affects the expression of EPHX1 mRNA CTD PMID:19159669 EPHX1 Human phenobarbital increases activity ISO Ephx1 (Mus musculus) 6480464 Phenobarbital results in increased activity of EPHX1 protein CTD PMID:3621371 EPHX1 Human phenobarbital multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [Phenobarbital co-treated with Diethylnitrosamine] results in increased expression of EPHX1 protein CTD PMID:20935162 EPHX1 Human phenol multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 EPHX1 protein promotes the reaction [[CYP2E1 protein results in increased metabolism of Benzene] which results in increased chemical synthesis of Phenol] more ... CTD PMID:8211999 EPHX1 Human phenols increases expression EXP 6480464 Phenols results in increased expression of EPHX1 mRNA CTD PMID:23561572 EPHX1 Human phenylglyoxylic acid multiple interactions EXP 6480464 EPHX1 polymorphism affects the metabolism of [mandelic acid co-treated with phenylglyoxylic acid] CTD PMID:25562543 EPHX1 Human phenylmercury acetate increases expression EXP 6480464 Phenylmercuric Acetate results in increased expression of EPHX1 mRNA CTD PMID:26272509 EPHX1 Human phenylmercury acetate multiple interactions EXP 6480464 [NOG protein co-treated with Phenylmercuric Acetate co-treated with dorsomorphin co-treated with 4-(5-benzo(1 and 3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of EPHX1 mRNA CTD PMID:27188386 EPHX1 Human phenytoin affects response to substance EXP 6480464 EPHX1 gene polymorphism affects the susceptibility to Phenytoin CTD PMID:19952982 EPHX1 Human phenytoin increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Phenytoin results in increased expression of EPHX1 mRNA CTD PMID:17381134 EPHX1 Human PhIP decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 2-amino-1-methyl-6-phenylimidazo(4 and 5-b)pyridine results in decreased expression of EPHX1 mRNA CTD PMID:12376462 EPHX1 Human phlorizin decreases expression ISO Ephx1 (Mus musculus) 6480464 Phlorhizin results in decreased expression of EPHX1 mRNA CTD PMID:22538082 EPHX1 Human phorbol 13-acetate 12-myristate decreases expression EXP 6480464 Tetradecanoylphorbol Acetate results in decreased expression of EPHX1 protein CTD PMID:24704207 EPHX1 Human phosphoramide mustard increases expression ISO Ephx1 (Rattus norvegicus) 6480464 phosphoramide mustard results in increased expression of EPHX1 mRNA and phosphoramide mustard results in increased expression of EPHX1 protein CTD PMID:25070981 EPHX1 Human pimecrolimus multiple interactions EXP 6480464 pimecrolimus inhibits the reaction [Rifampin results in increased expression of EPHX1 mRNA] CTD PMID:29356861 EPHX1 Human piperonyl butoxide increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Piperonyl Butoxide results in increased expression of EPHX1 mRNA CTD PMID:15890375 and PMID:22484513 EPHX1 Human pirinixic acid decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 pirinixic acid results in decreased expression of EPHX1 mRNA CTD PMID:19162173 EPHX1 Human pirinixic acid increases expression ISO Ephx1 (Mus musculus) 6480464 pirinixic acid results in increased expression of EPHX1 mRNA CTD PMID:15375163 more ... EPHX1 Human pirinixic acid increases expression ISO Ephx1 (Rattus norvegicus) 6480464 pirinixic acid results in increased expression of EPHX1 mRNA CTD PMID:15890375 EPHX1 Human pirinixic acid multiple interactions ISO Ephx1 (Mus musculus) 6480464 PPARA protein affects the reaction [pirinixic acid results in increased expression of EPHX1 mRNA] CTD PMID:16221962 EPHX1 Human pregnenolone 16alpha-carbonitrile increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Pregnenolone Carbonitrile results in increased expression of EPHX1 mRNA CTD PMID:19162173 EPHX1 Human pregnenolone 16alpha-carbonitrile increases expression ISO Ephx1 (Mus musculus) 6480464 Pregnenolone Carbonitrile results in increased expression of EPHX1 mRNA CTD PMID:20359477 and PMID:27413110 EPHX1 Human pregnenolone 16alpha-carbonitrile multiple interactions ISO Ephx1 (Mus musculus) 6480464 [Lithocholic Acid co-treated with Pregnenolone Carbonitrile] results in increased expression of EPHX1 mRNA CTD PMID:20359477 EPHX1 Human propiconazole affects expression ISO Ephx1 (Rattus norvegicus) 6480464 propiconazole affects the expression of EPHX1 mRNA CTD PMID:17383973 EPHX1 Human propiconazole increases expression ISO Ephx1 (Mus musculus) 6480464 propiconazole results in increased expression of EPHX1 mRNA CTD PMID:21278054 and PMID:22334560 EPHX1 Human propionamide decreases activity ISO Ephx1 (Rattus norvegicus) 6480464 propionamide analog results in decreased activity of EPHX1 protein CTD PMID:18363382 EPHX1 Human propionamide decreases activity ISO Ephx1 (Mus musculus) 6480464 propionamide analog results in decreased activity of EPHX1 protein CTD PMID:18363382 EPHX1 Human propionamide multiple interactions ISO Ephx1 (Mus musculus) 6480464 [propionamide analog results in decreased activity of EPHX1 protein] which results in increased glutathionylation of naphthalene CTD PMID:18363382 EPHX1 Human pyrazinecarboxamide increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Pyrazinamide results in increased expression of EPHX1 mRNA CTD PMID:22431067 EPHX1 Human quartz decreases expression EXP 6480464 Quartz results in decreased expression of EPHX1 mRNA CTD PMID:27917503 EPHX1 Human quercetin multiple interactions EXP 6480464 [Quercetin co-treated with Ascorbic Acid] results in decreased expression of EPHX1 mRNA CTD PMID:17639512 EPHX1 Human quercetin increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Quercetin results in increased expression of EPHX1 mRNA CTD PMID:18095365 and PMID:21565894 EPHX1 Human resveratrol multiple interactions EXP 6480464 resveratrol promotes the reaction [Benzo(a)pyrene results in increased activity of EPHX1 protein] CTD PMID:16484233 EPHX1 Human resveratrol affects expression ISO Ephx1 (Mus musculus) 6480464 resveratrol affects the expression of EPHX1 mRNA CTD PMID:23525482 EPHX1 Human resveratrol increases expression EXP 6480464 resveratrol results in increased expression of EPHX1 mRNA and resveratrol results in increased expression of EPHX1 protein CTD PMID:11279601 and PMID:18089832 EPHX1 Human rifampicin increases expression EXP 6480464 Rifampin results in increased expression of EPHX1 mRNA CTD PMID:22258563 more ... EPHX1 Human rifampicin multiple interactions EXP 6480464 pimecrolimus inhibits the reaction [Rifampin results in increased expression of EPHX1 mRNA] CTD PMID:29356861 EPHX1 Human rotenone increases expression ISO Ephx1 (Mus musculus) 6480464 Rotenone results in increased expression of EPHX1 mRNA CTD PMID:22016648 EPHX1 Human rotenone increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Rotenone results in increased expression of EPHX1 mRNA CTD PMID:28374803 EPHX1 Human SB 431542 multiple interactions EXP 6480464 [LDN 193189 co-treated with 4-(5-benzo(1 more ... CTD PMID:27188386 and PMID:37664457 EPHX1 Human sevoflurane affects expression ISO Ephx1 (Rattus norvegicus) 6480464 sevoflurane affects the expression of EPHX1 mRNA CTD PMID:15967596 EPHX1 Human silicon dioxide decreases expression EXP 6480464 Silicon Dioxide analog results in decreased expression of EPHX1 mRNA CTD PMID:25895662 EPHX1 Human silicon dioxide increases expression EXP 6480464 Silicon Dioxide results in increased expression of EPHX1 mRNA CTD PMID:27917503 EPHX1 Human silver atom multiple interactions EXP 6480464 NFE2L2 protein promotes the reaction [Silver results in increased expression of EPHX1 mRNA] CTD PMID:22036727 EPHX1 Human silver atom increases expression ISO Ephx1 (Mus musculus) 6480464 Silver results in increased expression of EPHX1 mRNA CTD PMID:27131904 EPHX1 Human silver atom increases expression EXP 6480464 Silver results in increased expression of EPHX1 mRNA CTD PMID:22036727 EPHX1 Human silver(0) multiple interactions EXP 6480464 NFE2L2 protein promotes the reaction [Silver results in increased expression of EPHX1 mRNA] CTD PMID:22036727 EPHX1 Human silver(0) increases expression ISO Ephx1 (Mus musculus) 6480464 Silver results in increased expression of EPHX1 mRNA CTD PMID:27131904 EPHX1 Human silver(0) increases expression EXP 6480464 Silver results in increased expression of EPHX1 mRNA CTD PMID:22036727 EPHX1 Human sodium arsenite increases expression EXP 6480464 sodium arsenite results in increased expression of EPHX1 mRNA CTD PMID:25493608 and PMID:38568856 EPHX1 Human sodium arsenite multiple interactions EXP 6480464 [sodium arsenite results in increased abundance of arsenite] which results in increased expression of EPHX1 mRNA CTD PMID:32076005 EPHX1 Human sodium dichromate decreases expression ISO Ephx1 (Mus musculus) 6480464 sodium bichromate results in decreased expression of EPHX1 mRNA CTD PMID:22155349 EPHX1 Human stilbene oxide multiple interactions ISO Ephx1 (Mus musculus) 6480464 araldite promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide analog] more ... CTD PMID:2043152 EPHX1 Human stilbene oxide increases metabolic processing ISO Ephx1 (Mus musculus) 6480464 EPHX1 protein results in increased metabolism of stilbene oxide and EPHX1 protein results in increased metabolism of stilbene oxide analog CTD PMID:2043152 EPHX1 Human stilbenoid increases activity ISO Ephx1 (Mus musculus) 6480464 Stilbenes results in increased activity of EPHX1 protein CTD PMID:3621371 EPHX1 Human streptozocin increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Streptozocin results in increased expression of EPHX1 protein CTD PMID:19634143 EPHX1 Human streptozocin multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 Trientine inhibits the reaction [Streptozocin results in increased expression of EPHX1 protein] CTD PMID:19634143 EPHX1 Human styrene increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Styrene results in increased expression of EPHX1 mRNA CTD PMID:16418063 EPHX1 Human styrene decreases response to substance ISO Ephx1 (Mus musculus) 6480464 EPHX1 protein results in decreased susceptibility to Styrene CTD PMID:22386858 EPHX1 Human styrene affects response to substance EXP 6480464 EPHX1 gene polymorphism affects the susceptibility to Styrene CTD PMID:14751678 EPHX1 Human styrene oxide multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 CYP1A1 protein promotes the reaction [EPHX1 protein affects the hydrolysis of styrene oxide] more ... CTD PMID:12051674 EPHX1 Human styrene oxide multiple interactions EXP 6480464 EPHX1 protein affects the metabolism of and results in decreased activity of styrene oxide CTD PMID:12694745 EPHX1 Human styrene oxide affects hydrolysis EXP 6480464 EPHX1 protein affects the hydrolysis of styrene oxide CTD PMID:11076696 EPHX1 Human sulfasalazine increases expression ISO Ephx1 (Mus musculus) 6480464 Sulfasalazine results in increased expression of EPHX1 mRNA CTD PMID:22016648 and PMID:31830553 EPHX1 Human sulforaphane increases expression ISO Ephx1 (Mus musculus) 6480464 sulforaphane results in increased expression of EPHX1 mRNA CTD PMID:17942926 EPHX1 Human sulforaphane increases expression EXP 6480464 sulforaphane results in increased expression of EPHX1 exon more ... CTD PMID:24704207 and PMID:31838189 EPHX1 Human sulforaphane multiple interactions EXP 6480464 sulforaphane promotes the reaction [NFE2L2 protein binds to EPHX1 enhancer] CTD PMID:24704207 EPHX1 Human sulforaphane multiple interactions ISO Ephx1 (Mus musculus) 6480464 [sulforaphane co-treated with dibenzoylmethane] results in increased expression of EPHX1 mRNA CTD PMID:17942926 EPHX1 Human sunitinib decreases expression EXP 6480464 Sunitinib results in decreased expression of EPHX1 mRNA CTD PMID:31533062 EPHX1 Human tamoxifen affects expression EXP 6480464 Tamoxifen affects the expression of EPHX1 mRNA CTD PMID:14699072 EPHX1 Human tamoxifen affects expression ISO Ephx1 (Mus musculus) 6480464 Tamoxifen affects the expression of EPHX1 mRNA CTD PMID:17555576 EPHX1 Human tert-butyl ethyl ether increases expression ISO Ephx1 (Rattus norvegicus) 6480464 ethyl tert-butyl ether results in increased expression of EPHX1 protein CTD PMID:24090815 EPHX1 Human tert-butyl hydroperoxide increases expression ISO Ephx1 (Mus musculus) 6480464 tert-Butylhydroperoxide results in increased expression of EPHX1 mRNA CTD PMID:21382384 EPHX1 Human testosterone increases expression ISO Ephx1 (Mus musculus) 6480464 Testosterone deficiency results in increased expression of EPHX1 mRNA CTD PMID:33848595 EPHX1 Human tetrachloromethane decreases expression ISO Ephx1 (Mus musculus) 6480464 Carbon Tetrachloride results in decreased expression of EPHX1 mRNA CTD PMID:17484886 EPHX1 Human tetrachloromethane multiple interactions ISO Ephx1 (Mus musculus) 6480464 [Carbon Tetrachloride co-treated with Ethanol] results in increased expression of EPHX1 mRNA CTD PMID:30517762 EPHX1 Human tetrachloromethane multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 Plant Extracts inhibits the reaction [Carbon Tetrachloride results in decreased expression of EPHX1 mRNA] and thymoquinone inhibits the reaction [Carbon Tetrachloride results in decreased expression of EPHX1 mRNA] CTD PMID:21994235 EPHX1 Human tetrachloromethane decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 Carbon Tetrachloride results in decreased expression of EPHX1 mRNA CTD PMID:21994235 EPHX1 Human tetracycline decreases expression ISO Ephx1 (Mus musculus) 6480464 Tetracycline results in decreased expression of EPHX1 mRNA CTD PMID:24489787 EPHX1 Human Tetramethylthiourea increases expression ISO Ephx1 (Rattus norvegicus) 6480464 tetramethylthiourea results in increased expression of EPHX1 mRNA and tetramethylthiourea results in increased expression of EPHX1 protein CTD PMID:10190572 EPHX1 Human tetraphene multiple interactions ISO Ephx1 (Mus musculus) 6480464 [Benzo(a)pyrene co-treated with benz(a)anthracene co-treated with benzo(b)fluoranthene co-treated with chrysene] results in increased expression of EPHX1 mRNA more ... CTD PMID:27858113 and PMID:8961944 EPHX1 Human tetraphene increases expression ISO Ephx1 (Mus musculus) 6480464 benz(a)anthracene results in increased expression of EPHX1 protein CTD PMID:2208584 EPHX1 Human tetraphene multiple interactions EXP 6480464 EPHX1 protein promotes the reaction [CYP1A1 protein results in increased metabolism of benz(a)anthracene] and EPHX1 protein promotes the reaction [CYP1A2 protein results in increased metabolism of benz(a)anthracene] CTD PMID:8961944 EPHX1 Human thiazoles increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Thiazoles results in increased expression of EPHX1 mRNA CTD PMID:8951341 EPHX1 Human thioacetamide multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [Diethylnitrosamine co-treated with Thioacetamide] results in increased expression of EPHX1 mRNA CTD PMID:28943392 EPHX1 Human thioacetamide increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Thioacetamide results in increased expression of EPHX1 mRNA CTD PMID:34492290 EPHX1 Human thymoquinone multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 thymoquinone inhibits the reaction [Carbon Tetrachloride results in decreased expression of EPHX1 mRNA] CTD PMID:21994235 EPHX1 Human titanium dioxide decreases expression ISO Ephx1 (Mus musculus) 6480464 titanium dioxide results in decreased expression of EPHX1 mRNA CTD PMID:23557971 more ... EPHX1 Human topotecan multiple interactions ISO Ephx1 (Rattus norvegicus) 6480464 [oxaliplatin co-treated with Topotecan] results in increased expression of EPHX1 mRNA CTD PMID:25729387 EPHX1 Human trichloroethene increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Trichloroethylene results in increased expression of EPHX1 mRNA CTD PMID:33387578 EPHX1 Human Tridiphane multiple interactions ISO Ephx1 (Mus musculus) 6480464 tridiphane promotes the reaction [EPHX1 protein results in increased metabolism of stilbene oxide] CTD PMID:2043152 EPHX1 Human triphenyl phosphate increases expression ISO Ephx1 (Rattus norvegicus) 6480464 triphenyl phosphate results in increased expression of EPHX1 mRNA CTD PMID:30589522 EPHX1 Human tris(2-butoxyethyl) phosphate affects expression EXP 6480464 tris(2-butoxyethyl) phosphate affects the expression of EPHX1 mRNA CTD PMID:29024780 EPHX1 Human trovafloxacin decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 trovafloxacin results in decreased expression of EPHX1 mRNA CTD PMID:24136188 EPHX1 Human valdecoxib increases expression ISO Ephx1 (Rattus norvegicus) 6480464 valdecoxib results in increased expression of EPHX1 mRNA CTD PMID:24136188 EPHX1 Human valproic acid increases expression ISO Ephx1 (Mus musculus) 6480464 Valproic Acid results in increased expression of EPHX1 mRNA CTD PMID:21427059 EPHX1 Human valproic acid decreases expression EXP 6480464 Valproic Acid results in decreased expression of EPHX1 mRNA CTD PMID:29501571 EPHX1 Human valproic acid decreases methylation EXP 6480464 Valproic Acid results in decreased methylation of EPHX1 gene CTD PMID:29154799 and PMID:29501571 EPHX1 Human valproic acid multiple interactions EXP 6480464 Valproic Acid affects the reaction [Colforsin affects the expression of EPHX1 mRNA] CTD PMID:20726872 EPHX1 Human valproic acid increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Valproic Acid results in increased expression of EPHX1 mRNA CTD PMID:17381134 EPHX1 Human vinclozolin affects expression ISO Ephx1 (Rattus norvegicus) 6480464 vinclozolin affects the expression of EPHX1 mRNA CTD PMID:19015723 EPHX1 Human vinclozolin decreases expression ISO Ephx1 (Rattus norvegicus) 6480464 vinclozolin results in decreased expression of EPHX1 mRNA CTD PMID:23034163 EPHX1 Human vincristine decreases expression ISO Ephx1 (Mus musculus) 6480464 Vincristine results in decreased expression of EPHX1 mRNA CTD PMID:21382384 EPHX1 Human warfarin affects response to substance EXP 6480464 EPHX1 gene polymorphism affects the susceptibility to Warfarin more ... CTD PMID:15900282 more ... EPHX1 Human warfarin increases response to substance EXP 6480464 EPHX1 protein results in increased susceptibility to Warfarin CTD PMID:17496169 EPHX1 Human zinc atom increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Zinc results in increased expression of EPHX1 mRNA CTD PMID:17074742 EPHX1 Human zinc sulfate increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Zinc Sulfate results in increased expression of EPHX1 mRNA CTD PMID:17074742 EPHX1 Human zinc(0) increases expression ISO Ephx1 (Rattus norvegicus) 6480464 Zinc results in increased expression of EPHX1 mRNA CTD PMID:17074742