PTGER3 (prostaglandin E receptor 3) - Rat Genome Database

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Gene: PTGER3 (prostaglandin E receptor 3) Homo sapiens
Analyze
Symbol: PTGER3
Name: prostaglandin E receptor 3
RGD ID: 731378
HGNC Page HGNC
Description: Predicted to enable prostaglandin E receptor activity. Predicted to be involved in several processes, including G protein-coupled receptor signaling pathway; negative regulation of gastric acid secretion; and positive regulation of fever generation. Predicted to act upstream of or within several processes, including bicarbonate transport; fever generation; and positive regulation of urine volume. Located in plasma membrane. Biomarker of leiomyoma.
Type: protein-coding
RefSeq Status: REVIEWED
Previously known as: EP3; EP3-I; EP3-II; EP3-III; EP3-IV; EP3-VI; EP3e; lnc003875; MGC141828; MGC141829; MGC27302; PGE receptor EP3 subtype; PGE receptor, EP3 subtype; PGE2 receptor EP3 subtype; PGE2-R; prostaglandin E receotor EP3 subtype 3 isoform; prostaglandin E receptor 3 (subtype EP3); prostaglandin E2 receptor EP3 subtype; prostaglandin receptor (PGE-2); prostanoid EP3 receptor
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38170,852,358 - 71,047,816 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl170,852,353 - 71,047,816 (-)EnsemblGRCh38hg38GRCh38
GRCh37171,318,041 - 71,513,499 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36171,090,624 - 71,286,079 (-)NCBINCBI36hg18NCBI36
Build 34171,188,848 - 71,225,512NCBI
Celera169,607,257 - 69,802,711 (-)NCBI
Cytogenetic Map1p31.1NCBI
HuRef169,428,653 - 69,623,748 (-)NCBIHuRef
CHM1_1171,432,956 - 71,628,842 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model


Gene-Chemical Interaction Annotations     Click to see Annotation Detail View
(+)-schisandrin B  (ISO)
1,2-dimethylhydrazine  (ISO)
1-chloro-2,4-dinitrobenzene  (EXP)
17beta-estradiol  (EXP,ISO)
2,2',4,4',5,5'-hexachlorobiphenyl  (ISO)
2,2',5,5'-tetrachlorobiphenyl  (ISO)
2,3,7,8-tetrachlorodibenzodioxine  (ISO)
2,4-D  (EXP)
2-butoxyethanol  (ISO)
2-hydroxypropanoic acid  (EXP)
3',5'-cyclic AMP  (ISO)
4,4'-sulfonyldiphenol  (EXP,ISO)
4-(ethoxymethylene)-2-phenyloxazol-5-one  (EXP)
4-amino-2,6-dinitrotoluene  (ISO)
6-propyl-2-thiouracil  (ISO)
acetamide  (ISO)
acetylsalicylic acid  (EXP)
acrylamide  (EXP)
aflatoxin B1  (ISO)
all-trans-retinoic acid  (ISO)
ammonium chloride  (ISO)
arsenite(3-)  (ISO)
benzo[a]pyrene  (EXP)
benzo[e]pyrene  (EXP)
bexarotene  (ISO)
bis(2-ethylhexyl) phthalate  (ISO)
bisphenol A  (EXP,ISO)
cadmium dichloride  (ISO)
calciol  (ISO)
calcium atom  (ISO)
calcium(0)  (ISO)
carbon nanotube  (ISO)
celecoxib  (ISO)
chlordecone  (ISO)
choline  (ISO)
ciglitazone  (EXP)
cisplatin  (EXP)
copper atom  (ISO)
copper(0)  (ISO)
dexamethasone  (EXP)
dextran sulfate  (ISO)
diuron  (ISO)
dorsomorphin  (EXP)
doxorubicin  (EXP)
endosulfan  (ISO)
eugenol  (EXP)
excitatory amino acid agonist  (ISO)
flutamide  (ISO)
folic acid  (ISO)
formaldehyde  (EXP,ISO)
genistein  (EXP,ISO)
glafenine  (ISO)
GW 4064  (ISO)
heptachlor  (ISO)
ibuprofen  (EXP)
ketoconazole  (EXP)
L-methionine  (ISO)
methapyrilene  (EXP)
mifepristone  (ISO)
misoprostol  (ISO)
monosodium L-glutamate  (ISO)
N-nitrosodiethylamine  (ISO)
nickel sulfate  (EXP)
paracetamol  (ISO)
paraquat  (ISO)
PCB138  (ISO)
phorbol 13-acetate 12-myristate  (ISO)
pirinixic acid  (ISO)
pristane  (ISO)
progesterone  (ISO)
prostaglandin E2  (EXP,ISO)
rac-lactic acid  (EXP)
raloxifene  (EXP)
rofecoxib  (EXP)
rotenone  (ISO)
SB 431542  (EXP)
Soman  (ISO)
staurosporine  (ISO)
sulforaphane  (ISO)
sulprostone  (ISO)
sunitinib  (EXP)
tamoxifen  (EXP)
terbinafine  (EXP)
tetrachloromethane  (ISO)
thioacetamide  (ISO)
titanium dioxide  (ISO)
Tributyltin oxide  (ISO)
trichostatin A  (EXP)
valproic acid  (EXP)
vinyl carbamate  (ISO)

Gene Ontology Annotations     Click to see Annotation Detail View

Biological Process
adenylate cyclase-activating G protein-coupled receptor signaling pathway  (IBA)
adenylate cyclase-modulating G protein-coupled receptor signaling pathway  (ISO)
bicarbonate transport  (ISO)
biological_process  (ND)
cell death  (TAS)
cellular response to forskolin  (ISO)
cellular response to interleukin-1  (ISO)
cellular response to lipopolysaccharide  (ISO)
desensitization of G protein-coupled receptor signaling pathway  (ISO)
female pregnancy  (ISO)
fever generation  (ISO)
G protein-coupled receptor signaling pathway  (IEA,TAS)
inflammatory response  (IBA)
intestine smooth muscle contraction  (IBA,ISO)
maternal process involved in parturition  (ISO)
negative regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway  (ISO)
negative regulation of calcium ion transmembrane transport  (ISO)
negative regulation of circadian sleep/wake cycle, wakefulness  (ISO)
negative regulation of forebrain neuron differentiation  (ISO)
negative regulation of gastric acid secretion  (IBA,ISO)
negative regulation of gastrin-induced gastric acid secretion  (ISO)
negative regulation of insulin secretion  (ISO)
negative regulation of norepinephrine secretion  (ISO)
negative regulation of platelet aggregation  (ISO)
negative regulation of potassium ion transmembrane transport  (ISO)
phospholipase C-activating G protein-coupled receptor signaling pathway  (IBA,ISO)
positive regulation of cAMP-mediated signaling  (ISO)
positive regulation of circadian sleep/wake cycle, non-REM sleep  (ISO)
positive regulation of colon smooth muscle contraction  (ISO)
positive regulation of cytosolic calcium ion concentration  (IBA,ISO)
positive regulation of fever generation  (ISS)
positive regulation of gastric mucosal blood circulation  (ISO)
positive regulation of gene expression  (ISO)
positive regulation of inhibitory G protein-coupled receptor phosphorylation  (ISO)
positive regulation of myofibroblast contraction  (ISO)
positive regulation of neutrophil extravasation  (ISO)
positive regulation of protein phosphorylation  (ISO)
positive regulation of smooth muscle contraction involved in micturition  (ISO)
positive regulation of urine volume  (ISO)
positive regulation of vasoconstriction  (ISO)
prostaglandin receptor internalization  (ISO)
receptor internalization  (ISO)
regulation of circadian sleep/wake cycle, wakefulness  (ISO)
regulation of norepinephrine secretion  (ISO)
response to estradiol  (ISO)
response to lipopolysaccharide  (ISO)
response to progesterone  (ISO)
response to salt  (ISO)
response to xenobiotic stimulus  (ISO)
signal transduction  (IEA)
urinary bladder smooth muscle contraction  (ISO)

Cellular Component

Molecular Function

Phenotype Annotations     Click to see Annotation Detail View

Human Phenotype
References

Additional References at PubMed
PMID:2834384   PMID:7476918   PMID:7759114   PMID:7883006   PMID:7981210   PMID:8075855   PMID:8117308   PMID:8135729   PMID:8307176   PMID:9065782   PMID:9073510   PMID:9154343  
PMID:10336471   PMID:10947062   PMID:11006128   PMID:11235015   PMID:12477932   PMID:12642666   PMID:12699873   PMID:12743126   PMID:12788892   PMID:14562138   PMID:14699136   PMID:15290741  
PMID:15304361   PMID:15489334   PMID:15528329   PMID:16274459   PMID:16707103   PMID:16710414   PMID:17207965   PMID:17496729   PMID:17644362   PMID:17877755   PMID:18005048   PMID:18023986  
PMID:18296611   PMID:18573679   PMID:18577758   PMID:18632791   PMID:18652829   PMID:18818748   PMID:18996083   PMID:19012178   PMID:19019335   PMID:19064572   PMID:19165680   PMID:19527514  
PMID:19799610   PMID:19913121   PMID:20110411   PMID:20140262   PMID:20237496   PMID:20379614   PMID:20452033   PMID:20452482   PMID:20503412   PMID:20516073   PMID:20587336   PMID:20628086  
PMID:20673868   PMID:20947153   PMID:21052031   PMID:21424266   PMID:21813027   PMID:21873635   PMID:21925169   PMID:21966456   PMID:22110249   PMID:22162473   PMID:22276108   PMID:22342278  
PMID:22397921   PMID:22421267   PMID:22870195   PMID:22915243   PMID:23349487   PMID:23364535   PMID:23382691   PMID:23406763   PMID:23493387   PMID:23805813   PMID:23904482   PMID:24180609  
PMID:25333975   PMID:25416956   PMID:26058972   PMID:26186194   PMID:26661165   PMID:27837675   PMID:28065721   PMID:28514442   PMID:28630103   PMID:28710231   PMID:28753926   PMID:29401613  
PMID:29532938   PMID:29661238   PMID:29892012   PMID:30338939   PMID:30402741   PMID:30481825   PMID:30510192   PMID:30510194   PMID:30655206   PMID:30835912   PMID:31097585   PMID:31485769  
PMID:32488496   PMID:32580276   PMID:33961781   PMID:34822808  


Genomics

Comparative Map Data
PTGER3
(Homo sapiens - human)
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38170,852,358 - 71,047,816 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh38.p13 Ensembl170,852,353 - 71,047,816 (-)EnsemblGRCh38hg38GRCh38
GRCh37171,318,041 - 71,513,499 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 36171,090,624 - 71,286,079 (-)NCBINCBI36hg18NCBI36
Build 34171,188,848 - 71,225,512NCBI
Celera169,607,257 - 69,802,711 (-)NCBI
Cytogenetic Map1p31.1NCBI
HuRef169,428,653 - 69,623,748 (-)NCBIHuRef
CHM1_1171,432,956 - 71,628,842 (-)NCBICHM1_1
Ptger3
(Mus musculus - house mouse)
Mouse AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCm393157,272,459 - 157,350,392 (+)NCBIGRCm39mm39
GRCm39 Ensembl3157,272,529 - 157,351,525 (+)Ensembl
GRCm383157,566,821 - 157,644,758 (+)NCBIGRCm38GRCm38mm10GRCm38
GRCm38.p6 Ensembl3157,566,892 - 157,645,888 (+)EnsemblGRCm38mm10GRCm38
MGSCv373157,229,856 - 157,307,722 (+)NCBIGRCm37mm9NCBIm37
MGSCv363157,502,185 - 157,580,051 (+)NCBImm8
Celera3164,034,893 - 164,113,113 (+)NCBICelera
Cytogenetic Map3H4NCBI
cM Map381.32NCBI
Ptger3
(Rattus norvegicus - Norway rat)
Rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
mRatBN7.22246,606,131 - 246,750,970 (+)NCBImRatBN7.2
mRatBN7.2 Ensembl2246,606,183 - 246,684,434 (+)Ensembl
Rnor_6.02263,895,093 - 263,979,682 (+)NCBIRnor6.0Rnor_6.0rn6Rnor6.0
Rnor_6.0 Ensembl2263,895,241 - 263,979,698 (+)EnsemblRnor6.0rn6Rnor6.0
Rnor_5.02282,614,936 - 282,760,641 (-)NCBIRnor5.0Rnor_5.0rn5Rnor5.0
RGSC_v3.42255,680,691 - 255,759,202 (+)NCBIRGSC3.4rn4RGSC3.4
RGSC_v3.12255,695,297 - 255,773,809 (+)NCBI
Celera2238,415,230 - 238,493,209 (+)NCBICelera
Cytogenetic Map2q45NCBI
Ptger3
(Chinchilla lanigera - long-tailed chinchilla)
Chinchilla AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChiLan1.0NW_00495542321,096,926 - 21,164,435 (+)NCBIChiLan1.0ChiLan1.0
PTGER3
(Pan paniscus - bonobo/pygmy chimpanzee)
Bonobo AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
PanPan1.1172,058,998 - 72,254,063 (-)NCBIpanpan1.1PanPan1.1panPan2
PanPan1.1 Ensembl172,059,441 - 72,254,063 (-)Ensemblpanpan1.1panPan2
Mhudiblu_PPA_v0170,076,610 - 70,271,475 (-)NCBIMhudiblu_PPA_v0panPan3
PTGER3
(Canis lupus familiaris - dog)
Dog AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
CanFam3.1674,932,789 - 74,986,573 (+)NCBICanFam3.1CanFam3.1canFam3CanFam3.1
Dog10K_Boxer_Tasha677,575,622 - 77,753,496 (+)NCBI
ROS_Cfam_1.0675,490,852 - 75,668,770 (+)NCBI
ROS_Cfam_1.0 Ensembl675,490,852 - 75,714,812 (+)Ensembl
UMICH_Zoey_3.1675,042,922 - 75,220,964 (+)NCBI
UNSW_CanFamBas_1.0674,940,272 - 75,118,118 (+)NCBI
UU_Cfam_GSD_1.0675,437,418 - 75,616,001 (+)NCBI
Ptger3
(Ictidomys tridecemlineatus - thirteen-lined ground squirrel)
Squirrel AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HiC_Itri_2NW_02440505883,239,312 - 83,315,450 (-)NCBI
SpeTri2.0NW_0049365911,174,364 - 1,250,233 (+)NCBISpeTri2.0SpeTri2.0SpeTri2.0
PTGER3
(Sus scrofa - pig)
Pig AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
Sscrofa11.1 Ensembl6141,958,954 - 142,161,292 (+)EnsemblSscrofa11.1susScr11Sscrofa11.1
Sscrofa11.16141,958,955 - 142,160,437 (+)NCBISscrofa11.1Sscrofa11.1susScr11Sscrofa11.1
Sscrofa10.26131,574,664 - 131,776,520 (+)NCBISscrofa10.2Sscrofa10.2susScr3
PTGER3
(Chlorocebus sabaeus - green monkey)
Green Monkey AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
ChlSab1.12062,093,830 - 62,293,360 (+)NCBIChlSab1.1chlSab2
ChlSab1.1 Ensembl2062,095,458 - 62,174,959 (+)EnsemblChlSab1.1chlSab2
Vero_WHO_p1.0NW_02366603355,495,971 - 55,576,801 (-)NCBIVero_WHO_p1.0
Ptger3
(Heterocephalus glaber - naked mole-rat)
Naked Mole-rat AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
HetGla 1.0NW_00462474225,177,340 - 25,356,911 (+)NCBIHetGla_female_1.0hetGla2

Position Markers
D1S192  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37171,486,324 - 71,486,526UniSTSGRCh37
Build 36171,258,912 - 71,259,114RGDNCBI36
Celera169,775,534 - 69,775,736RGD
Cytogenetic Map1p31.2UniSTS
HuRef169,596,546 - 69,596,752UniSTS
HuRef169,596,635 - 69,596,837UniSTS
Marshfield Genetic Map1102.02RGD
Marshfield Genetic Map1102.02UniSTS
Genethon Genetic Map1104.3UniSTS
TNG Radiation Hybrid Map139759.0UniSTS
Stanford-G3 RH Map13531.0UniSTS
GeneMap99-GB4 RH Map1187.68UniSTS
Whitehead-YAC Contig Map1 UniSTS
GeneMap99-G3 RH Map13487.0UniSTS
D1S1178  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37136,196,136 - 36,196,533UniSTSGRCh37
GRCh37171,446,882 - 71,447,147UniSTSGRCh37
Build 36135,968,723 - 35,969,120RGDNCBI36
Celera169,736,108 - 69,736,357UniSTS
Celera134,470,596 - 34,470,993RGD
Cytogenetic Map11q13.4-q13.5UniSTS
Cytogenetic Map1p31.2UniSTS
HuRef169,557,506 - 69,557,755UniSTS
HuRef1162,983,543 - 62,984,788UniSTS
Marshfield Genetic Map1101.48UniSTS
Marshfield Genetic Map1101.48RGD
D1S3370  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37171,418,220 - 71,418,343UniSTSGRCh37
Build 36171,190,808 - 71,190,931RGDNCBI36
Celera169,707,447 - 69,707,570RGD
Cytogenetic Map1p31.2UniSTS
HuRef169,528,849 - 69,528,972UniSTS
Whitehead-YAC Contig Map1 UniSTS
SHGC-84527  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37171,362,740 - 71,362,941UniSTSGRCh37
Build 36171,135,328 - 71,135,529RGDNCBI36
Celera169,651,961 - 69,652,162RGD
Cytogenetic Map1p31.2UniSTS
HuRef169,473,359 - 69,473,560UniSTS
TNG Radiation Hybrid Map139694.0UniSTS
RH122423  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37171,400,230 - 71,400,517UniSTSGRCh37
Build 36171,172,818 - 71,173,105RGDNCBI36
Celera169,689,458 - 69,689,745RGD
Cytogenetic Map1p31.2UniSTS
HuRef169,510,860 - 69,511,147UniSTS
TNG Radiation Hybrid Map139710.0UniSTS
D1S3321  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37171,318,075 - 71,318,403UniSTSGRCh37
Build 36171,090,663 - 71,090,991RGDNCBI36
Celera169,607,296 - 69,607,624RGD
Cytogenetic Map1p31.2UniSTS
HuRef169,428,692 - 69,429,020UniSTS
Stanford-G3 RH Map13549.0UniSTS
GeneMap99-GB4 RH Map1189.6UniSTS
Whitehead-RH Map1216.7UniSTS
Whitehead-YAC Contig Map1 UniSTS
GeneMap99-G3 RH Map13505.0UniSTS
PMC197251P3  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37171,512,626 - 71,513,020UniSTSGRCh37
Build 36171,285,214 - 71,285,608RGDNCBI36
Celera169,801,846 - 69,802,240RGD
Cytogenetic Map1p31.1UniSTS
Cytogenetic Map1p31.2UniSTS
HuRef169,622,883 - 69,623,277UniSTS
WI-22460  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37171,472,566 - 71,472,826UniSTSGRCh37
Build 36171,245,154 - 71,245,414RGDNCBI36
Celera169,761,777 - 69,762,037RGD
Cytogenetic Map1p31.2UniSTS
HuRef169,582,921 - 69,583,181UniSTS
GeneMap99-GB4 RH Map1189.6UniSTS
Whitehead-RH Map1216.7UniSTS
STS-Z40794  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37171,472,566 - 71,472,643UniSTSGRCh37
Build 36171,245,154 - 71,245,231RGDNCBI36
Celera169,761,777 - 69,761,854RGD
Cytogenetic Map1p31.2UniSTS
HuRef169,582,921 - 69,582,998UniSTS
GeneMap99-GB4 RH Map1187.68UniSTS
AL009426  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37171,483,997 - 71,484,139UniSTSGRCh37
Build 36171,256,585 - 71,256,727RGDNCBI36
Celera169,773,206 - 69,773,348RGD
Cytogenetic Map1p31.2UniSTS
HuRef169,594,307 - 69,594,449UniSTS
D1S2139  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37171,438,733 - 71,439,060UniSTSGRCh37
Build 36171,211,321 - 71,211,648RGDNCBI36
Celera169,727,970 - 69,728,287RGD
Cytogenetic Map1p31.2UniSTS
HuRef169,549,372 - 69,549,685UniSTS
Stanford-G3 RH Map13553.0UniSTS
Whitehead-RH Map1211.2UniSTS
Whitehead-YAC Contig Map1 UniSTS
D1S3367  
Human AssemblyChrPosition (strand)SourceJBrowse
GRCh37171,436,625 - 71,436,748UniSTSGRCh37
Build 36171,209,213 - 71,209,336RGDNCBI36
Celera169,725,851 - 69,725,974RGD
Cytogenetic Map1p31.2UniSTS
HuRef169,547,253 - 69,547,376UniSTS
GeneMap99-GB4 RH Map1189.89UniSTS
Whitehead-YAC Contig Map1 UniSTS
D1S192  
Human AssemblyChrPosition (strand)SourceJBrowse
Cytogenetic Map1p31.2UniSTS
TNG Radiation Hybrid Map139759.0UniSTS
Stanford-G3 RH Map13531.0UniSTS
GeneMap99-G3 RH Map13487.0UniSTS

miRNA Target Status

Predicted Target Of
Summary Value
Count of predictions:3946
Count of miRNA genes:1077
Interacting mature miRNAs:1316
Transcripts:ENST00000306666, ENST00000351052, ENST00000354608, ENST00000356595, ENST00000361210, ENST00000370924, ENST00000370931, ENST00000370932, ENST00000414819, ENST00000460330, ENST00000479353, ENST00000497146
Prediction methods:Microtar, Miranda, Rnahybrid, Targetscan
Result types:miRGate_prediction

The detailed report is available here: Full Report CSV TAB Printer

miRNA Target Status data imported from miRGate (http://mirgate.bioinfo.cnio.es/).
For more information about miRGate, see PMID:25858286 or access the full paper here.


Expression


RNA-SEQ Expression
High: > 1000 TPM value   Medium: Between 11 and 1000 TPM
Low: Between 0.5 and 10 TPM   Below Cutoff: < 0.5 TPM

alimentary part of gastrointestinal system circulatory system endocrine system exocrine system hemolymphoid system hepatobiliary system integumental system musculoskeletal system nervous system renal system reproductive system respiratory system sensory system visual system adipose tissue appendage entire extraembryonic component pharyngeal arch
High
Medium 457 990 3 3 21 2 1466 39 39 227 197 4 1 923 843 2
Low 1747 593 958 209 284 47 1675 957 1357 102 868 1088 166 1 281 988 3
Below cutoff 125 1356 692 348 1101 349 1155 1180 2216 35 320 414 1 956 2

Sequence

Nucleotide Sequences
RefSeq Transcripts NG_029509 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_001126044 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_198714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_198715 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_198716 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_198717 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_198718 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NM_198719 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_028292 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_028293 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  NR_028294 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XM_011541810 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  XR_946714 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
GenBank Nucleotide AB451481 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AI273491 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK290634 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AK315825 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL031429 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL050227 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL158087 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AL700981 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX814544 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX814552 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AX814554 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY387856 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  AY429108 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC024229 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC118578 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  BC118659 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CH471059 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CP068277 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  CS173017 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D38297 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D38298 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D38299 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D38300 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D38301 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D86096 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D86097 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  D86098 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  EF534325 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JA738749 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JA738751 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JA738753 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JA738755 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JA738757 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JA738759 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JA738761 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JA738763 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JA738765 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  JA738767 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  KF454969 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L26976 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L27488 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L27489 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L27490 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L32660 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L32661 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  L32662 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S68874 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S68875 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S69200 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  S69326 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U13214 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U13215 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U13216 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U13217 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  U13218 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X83857 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X83858 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X83859 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X83860 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X83861 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X83862 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles
  X83863 (Get FASTA)   NCBI Sequence Viewer   Search GEO for Microarray Profiles

Reference Sequences
RefSeq Acc Id: ENST00000306666   ⟹   ENSP00000302313
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl170,970,782 - 71,047,816 (-)Ensembl
RefSeq Acc Id: ENST00000351052   ⟹   ENSP00000280208
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl170,974,293 - 71,047,808 (-)Ensembl
RefSeq Acc Id: ENST00000354608   ⟹   ENSP00000346624
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl170,997,159 - 71,047,808 (-)Ensembl
RefSeq Acc Id: ENST00000356595   ⟹   ENSP00000349003
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl170,952,432 - 71,047,788 (-)Ensembl
RefSeq Acc Id: ENST00000361210   ⟹   ENSP00000424340
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl170,852,442 - 71,047,808 (-)Ensembl
RefSeq Acc Id: ENST00000370924   ⟹   ENSP00000359962
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl171,006,631 - 71,047,808 (-)Ensembl
RefSeq Acc Id: ENST00000370931   ⟹   ENSP00000359969
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl170,852,353 - 71,047,788 (-)Ensembl
RefSeq Acc Id: ENST00000370932   ⟹   ENSP00000359970
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl170,852,353 - 71,047,808 (-)Ensembl
RefSeq Acc Id: ENST00000460330   ⟹   ENSP00000418073
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl170,852,573 - 71,047,633 (-)Ensembl
RefSeq Acc Id: ENST00000479353   ⟹   ENSP00000421583
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl170,852,442 - 71,047,808 (-)Ensembl
RefSeq Acc Id: ENST00000497146   ⟹   ENSP00000423561
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl170,852,442 - 71,047,788 (-)Ensembl
RefSeq Acc Id: ENST00000628037   ⟹   ENSP00000486617
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38.p13 Ensembl170,852,353 - 71,047,808 (-)Ensembl
RefSeq Acc Id: NM_001126044   ⟹   NP_001119516
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38170,952,432 - 71,047,816 (-)NCBI
GRCh37171,318,036 - 71,513,497 (-)NCBI
HuRef169,428,653 - 69,623,748 (-)ENTREZGENE
CHM1_1171,533,463 - 71,628,842 (-)NCBI
Sequence:
RefSeq Acc Id: NM_198714   ⟹   NP_942007
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38170,852,358 - 71,047,816 (-)NCBI
GRCh37171,318,036 - 71,513,497 (-)NCBI
Build 36171,090,624 - 71,286,079 (-)NCBI Archive
HuRef169,428,653 - 69,623,748 (-)ENTREZGENE
CHM1_1171,432,956 - 71,628,842 (-)NCBI
Sequence:
RefSeq Acc Id: NM_198715   ⟹   NP_942008
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38171,005,860 - 71,047,816 (-)NCBI
GRCh37171,318,036 - 71,513,497 (-)NCBI
Build 36171,244,125 - 71,286,079 (-)NCBI Archive
HuRef169,428,653 - 69,623,748 (-)ENTREZGENE
CHM1_1171,586,885 - 71,628,842 (-)NCBI
Sequence:
RefSeq Acc Id: NM_198716   ⟹   NP_942009
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38170,852,358 - 71,047,816 (-)NCBI
GRCh37171,318,036 - 71,513,497 (-)NCBI
Build 36171,090,624 - 71,286,079 (-)NCBI Archive
HuRef169,428,653 - 69,623,748 (-)ENTREZGENE
CHM1_1171,432,956 - 71,628,842 (-)NCBI
Sequence:
RefSeq Acc Id: NM_198717   ⟹   NP_942010
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38170,852,358 - 71,047,816 (-)NCBI
GRCh37171,318,036 - 71,513,497 (-)NCBI
Build 36171,090,624 - 71,286,079 (-)NCBI Archive
HuRef169,428,653 - 69,623,748 (-)ENTREZGENE
CHM1_1171,432,956 - 71,628,842 (-)NCBI
Sequence:
RefSeq Acc Id: NM_198718   ⟹   NP_942011
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38170,952,432 - 71,047,816 (-)NCBI
GRCh37171,318,036 - 71,513,497 (-)NCBI
Build 36171,190,703 - 71,286,079 (-)NCBI Archive
HuRef169,428,653 - 69,623,748 (-)ENTREZGENE
CHM1_1171,533,463 - 71,628,842 (-)NCBI
Sequence:
RefSeq Acc Id: NM_198719   ⟹   NP_942012
RefSeq Status: REVIEWED
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38170,970,782 - 71,047,816 (-)NCBI
GRCh37171,318,036 - 71,513,497 (-)NCBI
Build 36171,209,052 - 71,286,079 (-)NCBI Archive
HuRef169,428,653 - 69,623,748 (-)ENTREZGENE
CHM1_1171,551,811 - 71,628,842 (-)NCBI
Sequence:
RefSeq Acc Id: NR_028292
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38170,852,358 - 71,047,816 (-)NCBI
GRCh37171,318,036 - 71,513,497 (-)NCBI
HuRef169,428,653 - 69,623,748 (-)ENTREZGENE
CHM1_1171,432,956 - 71,628,842 (-)NCBI
Sequence:
RefSeq Acc Id: NR_028293
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38170,852,358 - 71,047,816 (-)NCBI
GRCh37171,318,036 - 71,513,497 (-)NCBI
HuRef169,428,653 - 69,623,748 (-)ENTREZGENE
CHM1_1171,432,956 - 71,628,842 (-)NCBI
Sequence:
RefSeq Acc Id: NR_028294
RefSeq Status: REVIEWED
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38170,852,358 - 71,047,816 (-)NCBI
GRCh37171,318,036 - 71,513,497 (-)NCBI
HuRef169,428,653 - 69,623,748 (-)ENTREZGENE
CHM1_1171,432,956 - 71,628,842 (-)NCBI
Sequence:
RefSeq Acc Id: XM_011541810   ⟹   XP_011540112
RefSeq Status:
Type: CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38170,852,358 - 71,047,816 (-)NCBI
Sequence:
RefSeq Acc Id: XR_946714
RefSeq Status:
Type: NON-CODING
Position:
Human AssemblyChrPosition (strand)Source
GRCh38170,852,358 - 71,047,816 (-)NCBI
Sequence:
Protein Sequences
Protein RefSeqs NP_001119516 (Get FASTA)   NCBI Sequence Viewer  
  NP_942007 (Get FASTA)   NCBI Sequence Viewer  
  NP_942008 (Get FASTA)   NCBI Sequence Viewer  
  NP_942009 (Get FASTA)   NCBI Sequence Viewer  
  NP_942010 (Get FASTA)   NCBI Sequence Viewer  
  NP_942011 (Get FASTA)   NCBI Sequence Viewer  
  NP_942012 (Get FASTA)   NCBI Sequence Viewer  
  XP_011540112 (Get FASTA)   NCBI Sequence Viewer  
GenBank Protein AAA21130 (Get FASTA)   NCBI Sequence Viewer  
  AAA21131 (Get FASTA)   NCBI Sequence Viewer  
  AAA21132 (Get FASTA)   NCBI Sequence Viewer  
  AAA21133 (Get FASTA)   NCBI Sequence Viewer  
  AAA21134 (Get FASTA)   NCBI Sequence Viewer  
  AAA60076 (Get FASTA)   NCBI Sequence Viewer  
  AAA68191 (Get FASTA)   NCBI Sequence Viewer  
  AAA68192 (Get FASTA)   NCBI Sequence Viewer  
  AAA68193 (Get FASTA)   NCBI Sequence Viewer  
  AAB29854 (Get FASTA)   NCBI Sequence Viewer  
  AAB29855 (Get FASTA)   NCBI Sequence Viewer  
  AAB30208 (Get FASTA)   NCBI Sequence Viewer  
  AAC13372 (Get FASTA)   NCBI Sequence Viewer  
  AAC13373 (Get FASTA)   NCBI Sequence Viewer  
  AAC13374 (Get FASTA)   NCBI Sequence Viewer  
  AAD14026 (Get FASTA)   NCBI Sequence Viewer  
  AAH24229 (Get FASTA)   NCBI Sequence Viewer  
  AAI18579 (Get FASTA)   NCBI Sequence Viewer  
  AAI18660 (Get FASTA)   NCBI Sequence Viewer  
  AAQ90021 (Get FASTA)   NCBI Sequence Viewer  
  AAR07903 (Get FASTA)   NCBI Sequence Viewer  
  ABS57464 (Get FASTA)   NCBI Sequence Viewer  
  BAA07416 (Get FASTA)   NCBI Sequence Viewer  
  BAA07417 (Get FASTA)   NCBI Sequence Viewer  
  BAA07418 (Get FASTA)   NCBI Sequence Viewer  
  BAA07419 (Get FASTA)   NCBI Sequence Viewer  
  BAA07420 (Get FASTA)   NCBI Sequence Viewer  
  BAA19949 (Get FASTA)   NCBI Sequence Viewer  
  BAA19950 (Get FASTA)   NCBI Sequence Viewer  
  BAA19951 (Get FASTA)   NCBI Sequence Viewer  
  BAA19952 (Get FASTA)   NCBI Sequence Viewer  
  BAA19953 (Get FASTA)   NCBI Sequence Viewer  
  BAA19954 (Get FASTA)   NCBI Sequence Viewer  
  BAA19955 (Get FASTA)   NCBI Sequence Viewer  
  BAA19956 (Get FASTA)   NCBI Sequence Viewer  
  BAA19957 (Get FASTA)   NCBI Sequence Viewer  
  BAA19958 (Get FASTA)   NCBI Sequence Viewer  
  BAA19959 (Get FASTA)   NCBI Sequence Viewer  
  BAF83323 (Get FASTA)   NCBI Sequence Viewer  
  BAF98716 (Get FASTA)   NCBI Sequence Viewer  
  BAG70295 (Get FASTA)   NCBI Sequence Viewer  
  CAA58737 (Get FASTA)   NCBI Sequence Viewer  
  CAA58738 (Get FASTA)   NCBI Sequence Viewer  
  CAA58739 (Get FASTA)   NCBI Sequence Viewer  
  CAA58740 (Get FASTA)   NCBI Sequence Viewer  
  CAA58741 (Get FASTA)   NCBI Sequence Viewer  
  CAA58742 (Get FASTA)   NCBI Sequence Viewer  
  CAA58743 (Get FASTA)   NCBI Sequence Viewer  
  CAE83503 (Get FASTA)   NCBI Sequence Viewer  
  CAE83507 (Get FASTA)   NCBI Sequence Viewer  
  CAE83508 (Get FASTA)   NCBI Sequence Viewer  
  CAJ33690 (Get FASTA)   NCBI Sequence Viewer  
  CCF77027 (Get FASTA)   NCBI Sequence Viewer  
  CCF77028 (Get FASTA)   NCBI Sequence Viewer  
  CCF77029 (Get FASTA)   NCBI Sequence Viewer  
  CCF77030 (Get FASTA)   NCBI Sequence Viewer  
  CCF77031 (Get FASTA)   NCBI Sequence Viewer  
  CCF77032 (Get FASTA)   NCBI Sequence Viewer  
  CCF77033 (Get FASTA)   NCBI Sequence Viewer  
  CCF77034 (Get FASTA)   NCBI Sequence Viewer  
  CCF77035 (Get FASTA)   NCBI Sequence Viewer  
  CCF77036 (Get FASTA)   NCBI Sequence Viewer  
  EAX06436 (Get FASTA)   NCBI Sequence Viewer  
  EAX06437 (Get FASTA)   NCBI Sequence Viewer  
  EAX06438 (Get FASTA)   NCBI Sequence Viewer  
  EAX06439 (Get FASTA)   NCBI Sequence Viewer  
  EAX06440 (Get FASTA)   NCBI Sequence Viewer  
  EAX06441 (Get FASTA)   NCBI Sequence Viewer  
  EAX06442 (Get FASTA)   NCBI Sequence Viewer  
  EAX06443 (Get FASTA)   NCBI Sequence Viewer  
  EAX06444 (Get FASTA)   NCBI Sequence Viewer  
  EAX06445 (Get FASTA)   NCBI Sequence Viewer  
  EAX06446 (Get FASTA)   NCBI Sequence Viewer  
  P43115 (Get FASTA)   NCBI Sequence Viewer  
Reference Sequences
RefSeq Acc Id: NP_942010   ⟸   NM_198717
- Peptide Label: isoform 7
- UniProtKB: P43115 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_942009   ⟸   NM_198716
- Peptide Label: isoform 6
- UniProtKB: P43115 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_942007   ⟸   NM_198714
- Peptide Label: isoform 4
- UniProtKB: P43115 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_942011   ⟸   NM_198718
- Peptide Label: isoform 8
- UniProtKB: P43115 (UniProtKB/Swiss-Prot),   O00325 (UniProtKB/TrEMBL)
- Sequence:
RefSeq Acc Id: NP_001119516   ⟸   NM_001126044
- Peptide Label: isoform 4
- UniProtKB: P43115 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_942012   ⟸   NM_198719
- Peptide Label: isoform 4
- UniProtKB: P43115 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: NP_942008   ⟸   NM_198715
- Peptide Label: isoform 5
- UniProtKB: P43115 (UniProtKB/Swiss-Prot)
- Sequence:
RefSeq Acc Id: XP_011540112   ⟸   XM_011541810
- Peptide Label: isoform X1
- Sequence:
RefSeq Acc Id: ENSP00000302313   ⟸   ENST00000306666
RefSeq Acc Id: ENSP00000359962   ⟸   ENST00000370924
RefSeq Acc Id: ENSP00000359969   ⟸   ENST00000370931
RefSeq Acc Id: ENSP00000359970   ⟸   ENST00000370932
RefSeq Acc Id: ENSP00000421583   ⟸   ENST00000479353
RefSeq Acc Id: ENSP00000424340   ⟸   ENST00000361210
RefSeq Acc Id: ENSP00000486617   ⟸   ENST00000628037
RefSeq Acc Id: ENSP00000423561   ⟸   ENST00000497146
RefSeq Acc Id: ENSP00000280208   ⟸   ENST00000351052
RefSeq Acc Id: ENSP00000346624   ⟸   ENST00000354608
RefSeq Acc Id: ENSP00000349003   ⟸   ENST00000356595
RefSeq Acc Id: ENSP00000418073   ⟸   ENST00000460330
Protein Domains
G_PROTEIN_RECEP_F1_2

Protein Structures
Name Modeler Protein Id AA Range Protein Structure
AF-P43115-F1-model_v2 AlphaFold P43115 1-390 view protein structure

Promoters
RGD ID:6855880
Promoter ID:EPDNEW_H1105
Type:multiple initiation site
Name:PTGER3_1
Description:prostaglandin E receptor 3
SO ACC ID:SO:0000170
Source:EPDNEW (Eukaryotic Promoter Database, http://epd.vital-it.ch/)
Experiment Methods:Single-end sequencing.
Position:
Human AssemblyChrPosition (strand)Source
GRCh38171,047,811 - 71,047,871EPDNEW
RGD ID:6786340
Promoter ID:HG_KWN:3232
Type:CpG-Island
SO ACC ID:SO:0000170
Source:MPROMDB
Tissues & Cell Lines:CD4+TCell,   CD4+TCell_12Hour,   K562
Transcripts:ENST00000351052,   ENST00000354608,   ENST00000370932,   ENST00000370934,   NM_001126044,   NM_198714,   NM_198715,   NM_198716,   NM_198717,   NM_198718,   NM_198719,   NR_028292,   NR_028293,   NR_028294,   UC001DFM.1,   UC001DFN.2,   UC009WBM.1,   UC009WBN.1
Position:
Human AssemblyChrPosition (strand)Source
Build 36171,285,586 - 71,286,102 (-)MPROMDB

Clinical Variants
Name Type Condition(s) Position(s) Clinical significance
GRCh38/hg38 1p32.1-31.1(chr1:60473800-70944955)x1 copy number loss See cases [RCV000050703] Chr1:60473800..70944955 [GRCh38]
Chr1:60939472..71410638 [GRCh37]
Chr1:60712060..71183226 [NCBI36]
Chr1:1p32.1-31.1
pathogenic
GRCh38/hg38 1p32.3-31.1(chr1:52595352-76767765)x3 copy number gain See cases [RCV000051822] Chr1:52595352..76767765 [GRCh38]
Chr1:53061024..77233450 [GRCh37]
Chr1:52833612..77006038 [NCBI36]
Chr1:1p32.3-31.1
pathogenic
GRCh38/hg38 1p32.2-31.1(chr1:57350574-71325924)x1 copy number loss See cases [RCV000053841] Chr1:57350574..71325924 [GRCh38]
Chr1:57816246..71791607 [GRCh37]
Chr1:57588834..71564195 [NCBI36]
Chr1:1p32.2-31.1
pathogenic
GRCh38/hg38 1p32.1-31.1(chr1:59632500-76730877)x1 copy number loss See cases [RCV000053842] Chr1:59632500..76730877 [GRCh38]
Chr1:60098172..77196562 [GRCh37]
Chr1:59870760..76969150 [NCBI36]
Chr1:1p32.1-31.1
pathogenic
GRCh38/hg38 1p31.3-31.1(chr1:67239704-71924806)x1 copy number loss See cases [RCV000053843] Chr1:67239704..71924806 [GRCh38]
Chr1:67705387..72390489 [GRCh37]
Chr1:67477975..72163077 [NCBI36]
Chr1:1p31.3-31.1
pathogenic
NM_198714.1(PTGER3):c.1118C>T (p.Ser373Phe) single nucleotide variant Malignant melanoma [RCV000060240] Chr1:70974348 [GRCh38]
Chr1:71440031 [GRCh37]
Chr1:71212619 [NCBI36]
Chr1:1p31.1
not provided
NM_198714.1(PTGER3):c.918C>T (p.Ile306=) single nucleotide variant Malignant melanoma [RCV000060241] Chr1:71012464 [GRCh38]
Chr1:71478147 [GRCh37]
Chr1:71250735 [NCBI36]
Chr1:1p31.1
not provided
GRCh38/hg38 1p32.1-31.1(chr1:59760856-71578052)x1 copy number loss See cases [RCV000133710] Chr1:59760856..71578052 [GRCh38]
Chr1:60226528..72043735 [GRCh37]
Chr1:59999116..71816323 [NCBI36]
Chr1:1p32.1-31.1
pathogenic
GRCh38/hg38 1p32.1-22.3(chr1:58819605-86098611)x1 copy number loss See cases [RCV000136913] Chr1:58819605..86098611 [GRCh38]
Chr1:59285277..86564294 [GRCh37]
Chr1:59057865..86336882 [NCBI36]
Chr1:1p32.1-22.3
pathogenic
GRCh38/hg38 1p31.1(chr1:70907033-70991687)x1 copy number loss See cases [RCV000141296] Chr1:70907033..70991687 [GRCh38]
Chr1:71372716..71457370 [GRCh37]
Chr1:71145304..71229958 [NCBI36]
Chr1:1p31.1
uncertain significance
GRCh38/hg38 1p31.3-31.1(chr1:64072618-75518432)x3 copy number gain See cases [RCV000142452] Chr1:64072618..75518432 [GRCh38]
Chr1:64538290..75984117 [GRCh37]
Chr1:64310878..75756705 [NCBI36]
Chr1:1p31.3-31.1
pathogenic
GRCh38/hg38 1p31.3-31.1(chr1:66865125-77123381)x1 copy number loss See cases [RCV000143129] Chr1:66865125..77123381 [GRCh38]
Chr1:67330808..77589066 [GRCh37]
Chr1:67103396..77361654 [NCBI36]
Chr1:1p31.3-31.1
pathogenic
GRCh38/hg38 1p31.1(chr1:70716347-71407975)x3 copy number gain See cases [RCV000143773] Chr1:70716347..71407975 [GRCh38]
Chr1:71182030..71873658 [GRCh37]
Chr1:70954618..71646246 [NCBI36]
Chr1:1p31.1
likely benign
GRCh37/hg19 1p36.12-12(chr1:20608823-120546301)x3 copy number loss not provided [RCV000762767] Chr1:20608823..120546301 [GRCh37]
Chr1:1p36.12-12
likely benign
GRCh37/hg19 1p31.1(chr1:71415134-71468268)x1 copy number loss See cases [RCV000447312] Chr1:71415134..71468268 [GRCh37]
Chr1:1p31.1
likely benign
GRCh37/hg19 1p31.3-31.1(chr1:63252828-77402595)x1 copy number loss See cases [RCV000446378] Chr1:63252828..77402595 [GRCh37]
Chr1:1p31.3-31.1
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684)x3 copy number gain See cases [RCV000510383] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p31.3-22.3(chr1:64321264-88153669)x1 copy number loss See cases [RCV000511392] Chr1:64321264..88153669 [GRCh37]
Chr1:1p31.3-22.3
pathogenic|uncertain significance
GRCh37/hg19 1p36.33-q44(chr1:849467-249224684) copy number gain See cases [RCV000510926] Chr1:849467..249224684 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p31.3-31.1(chr1:61351024-79583933)x1 copy number loss See cases [RCV000512152] Chr1:61351024..79583933 [GRCh37]
Chr1:1p31.3-31.1
pathogenic
GRCh37/hg19 1p31.1(chr1:70885420-71331430)x3 copy number gain not provided [RCV000684585] Chr1:70885420..71331430 [GRCh37]
Chr1:1p31.1
uncertain significance
GRCh37/hg19 1p31.3-31.1(chr1:62434799-71656180)x3 copy number gain not provided [RCV000684577] Chr1:62434799..71656180 [GRCh37]
Chr1:1p31.3-31.1
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:47851-249228449)x3 copy number gain not provided [RCV000736295] Chr1:47851..249228449 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p36.33-q44(chr1:82154-249218992)x3 copy number gain not provided [RCV000736305] Chr1:82154..249218992 [GRCh37]
Chr1:1p36.33-q44
pathogenic
GRCh37/hg19 1p31.1(chr1:71414863-71465292)x1 copy number loss not provided [RCV000736532] Chr1:71414863..71465292 [GRCh37]
Chr1:1p31.1
benign
GRCh37/hg19 1p31.1(chr1:71414863-71458162)x1 copy number loss not provided [RCV000736531] Chr1:71414863..71458162 [GRCh37]
Chr1:1p31.1
benign
GRCh37/hg19 1p31.1(chr1:71410579-78131158) copy number gain not provided [RCV000767771] Chr1:71410579..78131158 [GRCh37]
Chr1:1p31.1
pathogenic
NM_198714.2(PTGER3):c.*23+784del deletion not provided [RCV000949648] Chr1:70952979 [GRCh38]
Chr1:71418662 [GRCh37]
Chr1:1p31.1
likely benign
NM_198719.2(PTGER3):c.111C>G (p.Leu37=) single nucleotide variant not provided [RCV000958458] Chr1:71047467 [GRCh38]
Chr1:71513150 [GRCh37]
Chr1:1p31.1
benign
GRCh37/hg19 1p31.1(chr1:71366112-71468493)x1 copy number loss not provided [RCV001005106] Chr1:71366112..71468493 [GRCh37]
Chr1:1p31.1
uncertain significance
GRCh37/hg19 1p36.22-21.1(chr1:103343285-103455144)x3 copy number gain Global developmental delay [RCV000787285] Chr1:103343285..103455144 [GRCh37]
Chr1:1p36.22-21.1
uncertain significance
GRCh37/hg19 1p31.3-22.3(chr1:67851233-86101340)x1 copy number loss not provided [RCV000846441] Chr1:67851233..86101340 [GRCh37]
Chr1:1p31.3-22.3
pathogenic
Single allele deletion Intellectual disability, severe [RCV000824954] Chr1:59922631..72058653 [GRCh37]
Chr1:1p32.1-31.1
pathogenic
Single allele deletion not provided [RCV000844927] Chr1:66085524..88429789 [GRCh37]
Chr1:1p31.3-22.2
not provided
GRCh37/hg19 1p31.3-31.1(chr1:66868168-77106425)x1 copy number loss not provided [RCV000847457] Chr1:66868168..77106425 [GRCh37]
Chr1:1p31.3-31.1
pathogenic
GRCh37/hg19 1p31.1(chr1:71419650-72398325)x1 copy number loss not provided [RCV001005107] Chr1:71419650..72398325 [GRCh37]
Chr1:1p31.1
uncertain significance
GRCh37/hg19 1p31.3-22.1(chr1:68180293-92731957) copy number loss not specified [RCV002053392] Chr1:68180293..92731957 [GRCh37]
Chr1:1p31.3-22.1
pathogenic

Additional Information

Database Acc Id Source(s)
AGR Gene HGNC:9595 AgrOrtholog
COSMIC PTGER3 COSMIC
Ensembl Genes ENSG00000050628 Ensembl, ENTREZGENE, UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Ensembl Protein ENSP00000280208 UniProtKB/Swiss-Prot
  ENSP00000302313 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000346624 UniProtKB/TrEMBL
  ENSP00000349003 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000359962 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000359969 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000359970 UniProtKB/TrEMBL
  ENSP00000418073 ENTREZGENE, UniProtKB/Swiss-Prot
  ENSP00000421583 UniProtKB/Swiss-Prot
  ENSP00000423561 UniProtKB/TrEMBL
  ENSP00000424340 UniProtKB/TrEMBL
  ENSP00000486617 ENTREZGENE, UniProtKB/Swiss-Prot
Ensembl Transcript ENST00000306666 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000351052 UniProtKB/Swiss-Prot
  ENST00000354608 UniProtKB/TrEMBL
  ENST00000356595 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000361210 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000370924 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000370931 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000370932 UniProtKB/TrEMBL
  ENST00000460330 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000479353 ENTREZGENE, UniProtKB/Swiss-Prot
  ENST00000497146 ENTREZGENE, UniProtKB/TrEMBL
  ENST00000628037 ENTREZGENE, UniProtKB/Swiss-Prot
GTEx ENSG00000050628 GTEx
HGNC ID HGNC:9595 ENTREZGENE
Human Proteome Map PTGER3 Human Proteome Map
InterPro EP3_rcpt_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  GPCR_Rhodpsn_7TM UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prostanoid_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prostglndn_DP_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  Prostglndn_EP3_rcpt UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
KEGG Report hsa:5733 UniProtKB/Swiss-Prot
NCBI Gene 5733 ENTREZGENE
OMIM 176806 OMIM
PANTHER PTHR11866 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PTHR11866:SF10 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
Pfam 7tm_1 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PharmGKB PA288 PharmGKB
PRINTS GPCRRHODOPSN UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROSTAGLNDNR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PROSTANOIDR UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRSTNOIDE32R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
  PRSTNOIDEP3R UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
PROSITE G_PROTEIN_RECEP_F1_2 UniProtKB/Swiss-Prot, UniProtKB/TrEMBL
UniProt A0A0A0MRP3_HUMAN UniProtKB/TrEMBL
  A0A0B4J204_HUMAN UniProtKB/TrEMBL
  B2KKV4_HUMAN UniProtKB/TrEMBL
  F8WAJ7_HUMAN UniProtKB/TrEMBL
  O00325 ENTREZGENE, UniProtKB/TrEMBL
  P43115 ENTREZGENE, UniProtKB/Swiss-Prot
  Q147U0_HUMAN UniProtKB/TrEMBL
  Q6TTN3_HUMAN UniProtKB/TrEMBL
UniProt Secondary B0AZN4 UniProtKB/Swiss-Prot
  B1AK19 UniProtKB/Swiss-Prot
  B5BUP5 UniProtKB/Swiss-Prot
  O00326 UniProtKB/Swiss-Prot
  Q12943 UniProtKB/Swiss-Prot
  Q12944 UniProtKB/Swiss-Prot
  Q12945 UniProtKB/Swiss-Prot
  Q147X8 UniProtKB/Swiss-Prot
  Q16546 UniProtKB/Swiss-Prot
  Q5CZ59 UniProtKB/Swiss-Prot
  Q5CZ61 UniProtKB/Swiss-Prot
  Q5CZ62 UniProtKB/Swiss-Prot
  Q5CZ63 UniProtKB/Swiss-Prot
  Q5CZ64 UniProtKB/Swiss-Prot


Nomenclature History
Date Current Symbol Current Name Previous Symbol Previous Name Description Reference Status
2015-11-24 PTGER3  prostaglandin E receptor 3    prostaglandin E receptor 3 (subtype EP3)  Symbol and/or name change 5135510 APPROVED