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Gene: IL17A (interleukin 17A) Homo sapiens
Symbol: IL17A
Name: interleukin 17A
Description: Predicted to have cytokine activity. Involved in several processes, including interleukin-17-mediated signaling pathway; positive regulation of cytokine production; and positive regulation of osteoclast differentiation. Predicted to localize to extracellular region. Implicated in several diseases, including Graves' disease; Mycobacterium avium complex disease; bone inflammation disease (multiple); bronchial disease (multiple); and rhinitis (multiple). Biomarker of several diseases, including autoimmune hypersensitivity disease (multiple); eye disease (multiple); lung disease (multiple); rhinitis (multiple); and vasculitis (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CTLA-8; CTLA8; cytotoxic T-lymphocyte-associated antigen 8; cytotoxic T-lymphocyte-associated protein 8; cytotoxic T-lymphocyte-associated serine esterase 8; IL-17; IL-17A; IL17; interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8); interleukin-17A
Mus musculus (house mouse) : Il17a (interleukin 17A)  MGI  Alliance
Rattus norvegicus (Norway rat) : Il17a (interleukin 17A)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Il17a (interleukin 17A)
Pan paniscus (bonobo/pygmy chimpanzee) : IL17A (interleukin 17A)
Canis lupus familiaris (dog) : IL17A (interleukin 17A)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Il17a (interleukin 17A)
Sus scrofa (pig) : IL17A (interleukin 17A)
Chlorocebus sabaeus (African green monkey) : IL17A (interleukin 17A)
Heterocephalus glaber (naked mole-rat) : Il17a (interleukin 17A)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Human AssemblyChrPosition (strand)SourceGenome Browsers
GRCh38 Ensembl652,186,375 - 52,190,638 (+)EnsemblGRCh38hg38GRCh38
GRCh38652,186,375 - 52,190,638 (+)NCBIGRCh38GRCh38hg38GRCh38
GRCh37652,051,185 - 52,055,436 (+)NCBIGRCh37GRCh37hg19GRCh37
Build 36652,159,144 - 52,163,395 (+)NCBINCBI36hg18NCBI36
Build 34652,159,143 - 52,163,395NCBI
Celera653,712,308 - 53,716,559 (+)NCBI
Cytogenetic Map6p12.2NCBI
HuRef651,882,254 - 51,886,505 (+)NCBIHuRef
CHM1_1652,053,438 - 52,057,689 (+)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)

Disease Annotations
Gene-Chemical Interaction Annotations
Gene Ontology Annotations
Molecular Pathway Annotations
Phenotype Annotations
References - curated
References - uncurated


Comparative Map Data
Position Markers
miRNA Target Status


RNA-SEQ Expression


Nucleotide Sequences
Protein Sequences
Clinical Variants

Additional Information

External Database Links
More on IL17A
Alliance Gene
Ensembl Gene
JBrowse: hg19 hg38
HGNC Report
NCBI Genome Data Viewer

RGD Object Information
RGD ID: 735883
Created: 2004-02-06
Species: Homo sapiens
Last Modified: 2020-06-30
Status: ACTIVE


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.