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Gene: RELA (RELA proto-oncogene, NF-kB subunit) Homo sapiens
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Symbol: RELA
Name: RELA proto-oncogene, NF-kB subunit
Description: Exhibits several functions, including DNA binding activity; enzyme binding activity; and transcription factor binding activity. Involved in several processes, including cellular response to molecule of bacterial origin; regulation of RNA metabolic process; and regulation of signal transduction. Localizes to several cellular components, including NF-kappaB p50/p65 complex; cytosol; and nuclear chromatin. Implicated in ductal carcinoma in situ; lung non-small cell carcinoma; lymphoma; and renal cell carcinoma. Biomarker of several diseases, including cervix uteri carcinoma in situ; middle ear disease (multiple); obstructive sleep apnea; prostate disease (multiple); and urinary system cancer (multiple).
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: CMCU; MGC131774; NF-kappa-B p65delta3; NF-kappa-B transcription factor p65; NFKB3; nuclear factor NF-kappa-B p65 subunit; nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; p65; transcription factor p65; v-rel avian reticuloendotheliosis viral oncogene homolog A; v-rel avian reticuloendotheliosis viral oncogene homolog A (nuclear factor of kappa light polypeptide gene enhancer in B-cells 3 (p65)); v-rel reticuloendotheliosis viral oncogene homolog A; v-rel reticuloendotheliosis viral oncogene homolog A, nuclear factor of kappa light polypeptide gene enhancer in B-cells 3, p65
Orthologs:
Mus musculus (house mouse) : Rela (v-rel reticuloendotheliosis viral oncogene homolog A (avian))  MGI  Alliance
Rattus norvegicus (Norway rat) : Rela (RELA proto-oncogene, NF-kB subunit)  Alliance
Chinchilla lanigera (long-tailed chinchilla) : Rela (RELA proto-oncogene, NF-kB subunit)
Pan paniscus (bonobo/pygmy chimpanzee) : RELA (RELA proto-oncogene, NF-kB subunit)
Canis lupus familiaris (dog) : RELA (RELA proto-oncogene, NF-kB subunit)
Ictidomys tridecemlineatus (thirteen-lined ground squirrel) : Rela (RELA proto-oncogene, NF-kB subunit)
Sus scrofa (pig) : RELA (RELA proto-oncogene, NF-kB subunit)
Chlorocebus sabaeus (African green monkey) : RELA (RELA proto-oncogene, NF-kB subunit)
Heterocephalus glaber (naked mole-rat) : Rela (RELA proto-oncogene, NF-kB subunit)
more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl1165,653,597 - 65,663,090 (-)EnsemblGRCh38hg38GRCh38
GRCh381165,653,596 - 65,662,972 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh371165,421,067 - 65,430,443 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 361165,178,393 - 65,186,951 (-)NCBINCBI36hg18NCBI36
Build 341165,178,392 - 65,186,951NCBI
Celera1162,747,772 - 62,757,128 (-)NCBI
Cytogenetic Map11q13.1NCBI
HuRef1161,748,056 - 61,757,436 (-)NCBIHuRef
CHM1_11165,305,002 - 65,314,374 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model