FGFR2 (fibroblast growth factor receptor 2) - Rat Genome Database

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Gene: FGFR2 (fibroblast growth factor receptor 2) Homo sapiens
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Symbol: FGFR2
Name: fibroblast growth factor receptor 2
RGD ID: 736865
HGNC Page HGNC
Description: Exhibits fibroblast growth factor binding activity; fibroblast growth factor-activated receptor activity; and protein homodimerization activity. Involved in several processes, including embryonic cranial skeleton morphogenesis; negative regulation of keratinocyte proliferation; and protein phosphorylation. Localizes to several cellular components, including cell cortex; cell surface; and integral component of plasma membrane. Colocalizes with collagen-containing extracellular matrix. Implicated in several diseases, including Antley-Bixler syndrome; Beare-Stevenson cutis gyrata syndrome; Jackson-Weiss syndrome; LADD syndrome; and synostosis (multiple). Biomarker of endometriosis; prostate cancer; squamous cell carcinoma; stomach cancer; and transitional cell carcinoma.
Type: protein-coding
RefSeq Status: REVIEWED
Also known as: bacteria-expressed kinase; BBDS; BEK; BEK fibroblast growth factor receptor; BFR-1; CD332; CEK3; CFD1; ECT1; FGF receptor; FGFR-2; FGFR2-AHCYL1 fusion kinase protein; fibroblast growth factor receptor 2 (bacteria-expressed kinase, keratinocyte growth factor receptor, craniofacial dysostosis 1, Crouzon syndrome, Pfeiffer syndrome, Jackson-Weiss syndrome); fibroblast growth factor receptor 2 isoform IgIIIb isoform; fibroblast growth factor receptor 2 isoform IgIIIc isoform; fibroblast growth factor receptor 2 Ksam IV secreted isoform; FLJ98662; hydroxyaryl-protein kinase; JWS; K-SAM; keratinocyte growth factor receptor; KGFR; protein tyrosine kinase, receptor like 14; soluble FGFR4 variant 4; TK14; TK25
RGD Orthologs
Mouse
Rat
Chinchilla
Bonobo
Dog
Squirrel
Pig
Green Monkey
Naked Mole-Rat
Alliance Genes
More Info more info ...
Allele / Splice: See ClinVar data
Latest Assembly: GRCh38 - Human Genome Assembly GRCh38
Position:
Human AssemblyChrPosition (strand)SourceGenome Browsers
JBrowseNCBIUCSCEnsembl
GRCh38.p13 Ensembl10121,478,334 - 121,598,458 (-)EnsemblGRCh38hg38GRCh38
GRCh38.p13 Ensembl10121,478,332 - 121,598,458 (-)EnsemblGRCh38hg38GRCh38
GRCh3810121,478,330 - 121,598,458 (-)NCBIGRCh38GRCh38hg38GRCh38
GRCh3710123,237,844 - 123,357,972 (-)NCBIGRCh37GRCh37hg19GRCh37
Build 3610123,227,845 - 123,347,962 (-)NCBINCBI36hg18NCBI36
Build 3410123,266,837 - 123,347,907NCBI
Celera10116,970,097 - 117,089,799 (-)NCBI
Cytogenetic Map10q26.13NCBI
HuRef10116,868,799 - 116,988,666 (-)NCBIHuRef
CHM1_110123,522,903 - 123,642,701 (-)NCBICHM1_1
JBrowse: View Region in Genome Browser (JBrowse)
Model